ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MDOLOOFK_00001 8.29e-75 yloU - - S - - - Asp23 family, cell envelope-related function
MDOLOOFK_00002 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
MDOLOOFK_00003 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MDOLOOFK_00004 9e-315 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
MDOLOOFK_00005 3.07e-149 - - - L - - - Resolvase, N-terminal
MDOLOOFK_00006 9.21e-78 - - - - - - - -
MDOLOOFK_00007 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
MDOLOOFK_00008 0.0 - - - P - - - P-loop Domain of unknown function (DUF2791)
MDOLOOFK_00009 3.9e-173 - - - S - - - TerB-C domain
MDOLOOFK_00010 2.27e-218 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MDOLOOFK_00011 3.3e-158 casE - - S ko:K19126 - ko00000,ko02048 CRISPR_assoc
MDOLOOFK_00012 8.67e-170 casD - - S ko:K19125 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas5)
MDOLOOFK_00013 2.91e-255 casC - - L ko:K19124 - ko00000,ko02048 CT1975-like protein
MDOLOOFK_00014 1.85e-142 - - - S ko:K19046 - ko00000,ko02048 CRISPR-associated protein Cse2 (CRISPR_cse2)
MDOLOOFK_00015 1.43e-139 casA - - L ko:K19123 - ko00000,ko02048 the current gene model (or a revised gene model) may contain a frame shift
MDOLOOFK_00016 4.43e-224 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MDOLOOFK_00017 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MDOLOOFK_00018 9.31e-72 ftsL - - D - - - Cell division protein FtsL
MDOLOOFK_00019 4.45e-225 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MDOLOOFK_00020 5.63e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MDOLOOFK_00021 4.43e-47 - - - KQ - - - helix_turn_helix, mercury resistance
MDOLOOFK_00022 8.56e-105 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MDOLOOFK_00024 2.57e-138 - - - K ko:K06977 - ko00000 acetyltransferase
MDOLOOFK_00025 2.7e-121 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MDOLOOFK_00026 6.59e-227 ybcH - - D ko:K06889 - ko00000 Alpha beta
MDOLOOFK_00027 7.74e-61 - - - - - - - -
MDOLOOFK_00028 1.76e-277 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
MDOLOOFK_00029 1.69e-262 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
MDOLOOFK_00030 1.28e-274 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MDOLOOFK_00031 3.22e-135 - - - S ko:K06872 - ko00000 TPM domain
MDOLOOFK_00032 4.29e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
MDOLOOFK_00033 1.07e-211 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MDOLOOFK_00034 3.07e-142 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MDOLOOFK_00035 5.68e-110 - - - S - - - Protein of unknown function (DUF1694)
MDOLOOFK_00036 2.4e-276 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MDOLOOFK_00037 1.11e-55 - - - - - - - -
MDOLOOFK_00038 1.83e-101 uspA - - T - - - universal stress protein
MDOLOOFK_00039 9.93e-170 - - - S - - - zinc-ribbon domain
MDOLOOFK_00040 1.23e-166 - - - S - - - (CBS) domain
MDOLOOFK_00041 1.33e-275 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDOLOOFK_00042 1.23e-75 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MDOLOOFK_00043 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MDOLOOFK_00044 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MDOLOOFK_00045 1.07e-52 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MDOLOOFK_00046 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
MDOLOOFK_00047 1.64e-200 yhaX - - S - - - Sucrose-6F-phosphate phosphohydrolase
MDOLOOFK_00048 0.0 - - - E - - - amino acid
MDOLOOFK_00049 5.66e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MDOLOOFK_00050 1.05e-47 - - - - - - - -
MDOLOOFK_00051 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
MDOLOOFK_00052 1.35e-180 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MDOLOOFK_00053 3.41e-132 yitW - - S - - - Iron-sulfur cluster assembly protein
MDOLOOFK_00054 2.19e-292 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
MDOLOOFK_00055 9.18e-187 - - - S - - - Protein of unknown function (DUF1002)
MDOLOOFK_00056 2.41e-188 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDOLOOFK_00057 1.51e-233 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MDOLOOFK_00058 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDOLOOFK_00059 4.62e-58 - - - - - - - -
MDOLOOFK_00060 2.11e-248 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MDOLOOFK_00061 2.28e-221 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MDOLOOFK_00062 1.34e-58 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MDOLOOFK_00063 5.11e-81 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MDOLOOFK_00064 6.13e-261 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MDOLOOFK_00065 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MDOLOOFK_00066 1.82e-86 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
MDOLOOFK_00067 2.49e-227 lipA - - I - - - Carboxylesterase family
MDOLOOFK_00069 2.72e-236 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MDOLOOFK_00070 9.65e-181 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
MDOLOOFK_00071 3.51e-222 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
MDOLOOFK_00072 3.92e-83 - - - S - - - Domain of unknown function (DUF956)
MDOLOOFK_00073 1.77e-204 - - - K - - - Transcriptional regulator
MDOLOOFK_00074 3.36e-100 copY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
MDOLOOFK_00075 1.79e-77 - - - S - - - Cupredoxin-like domain
MDOLOOFK_00076 4.44e-65 - - - S - - - Cupredoxin-like domain
MDOLOOFK_00077 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MDOLOOFK_00078 6.63e-147 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
MDOLOOFK_00079 3.14e-137 - - - - - - - -
MDOLOOFK_00080 1.25e-182 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
MDOLOOFK_00082 2.84e-80 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
MDOLOOFK_00083 5.34e-146 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MDOLOOFK_00084 1.09e-91 - - - S - - - Iron-sulphur cluster biosynthesis
MDOLOOFK_00086 1.04e-41 - - - - - - - -
MDOLOOFK_00087 1.18e-221 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
MDOLOOFK_00088 1.25e-17 - - - - - - - -
MDOLOOFK_00089 2.05e-286 ynbB - - P - - - aluminum resistance
MDOLOOFK_00090 8.08e-218 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MDOLOOFK_00091 6.77e-87 yqhL - - P - - - Rhodanese-like protein
MDOLOOFK_00092 1e-47 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
MDOLOOFK_00093 6.56e-154 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
MDOLOOFK_00094 1.94e-126 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MDOLOOFK_00095 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MDOLOOFK_00096 2.43e-25 - - - K - - - Putative ATP-dependent DNA helicase recG C-terminal
MDOLOOFK_00097 5.1e-291 - - - S - - - SLAP domain
MDOLOOFK_00098 2.38e-51 - - - S - - - Protein of unknown function (DUF2922)
MDOLOOFK_00099 1.21e-40 - - - - - - - -
MDOLOOFK_00100 2.77e-25 - - - - - - - -
MDOLOOFK_00101 7.16e-147 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
MDOLOOFK_00102 3.03e-159 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
MDOLOOFK_00103 8.54e-81 - - - - - - - -
MDOLOOFK_00104 8.98e-164 - - - S - - - haloacid dehalogenase-like hydrolase
MDOLOOFK_00105 6.82e-292 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MDOLOOFK_00106 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MDOLOOFK_00107 1.34e-183 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MDOLOOFK_00108 1.24e-172 - - - S - - - Protein of unknown function (DUF975)
MDOLOOFK_00109 1.97e-227 pbpX2 - - V - - - Beta-lactamase
MDOLOOFK_00110 2.72e-315 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MDOLOOFK_00111 4.98e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDOLOOFK_00112 3.08e-306 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
MDOLOOFK_00113 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDOLOOFK_00114 9.18e-27 - - - S - - - D-Ala-teichoic acid biosynthesis protein
MDOLOOFK_00115 6.47e-64 - - - - - - - -
MDOLOOFK_00116 8.03e-278 - - - S - - - Membrane
MDOLOOFK_00117 7.51e-196 - - - I - - - alpha/beta hydrolase fold
MDOLOOFK_00118 3.2e-143 - - - S - - - SNARE associated Golgi protein
MDOLOOFK_00119 1.23e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MDOLOOFK_00120 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MDOLOOFK_00121 6.21e-277 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MDOLOOFK_00122 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
MDOLOOFK_00123 5.51e-73 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MDOLOOFK_00124 2.81e-174 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MDOLOOFK_00125 2.95e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MDOLOOFK_00126 6.78e-60 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MDOLOOFK_00127 1.63e-290 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MDOLOOFK_00128 5.56e-72 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MDOLOOFK_00129 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MDOLOOFK_00130 3.44e-201 - - - S - - - Phospholipase, patatin family
MDOLOOFK_00131 3.84e-191 - - - S - - - hydrolase
MDOLOOFK_00132 8.32e-157 vanR - - K - - - response regulator
MDOLOOFK_00133 5.37e-270 - - - T - - - His Kinase A (phosphoacceptor) domain
MDOLOOFK_00134 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MDOLOOFK_00135 7.79e-186 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MDOLOOFK_00136 1.03e-130 - - - GM - - - NmrA-like family
MDOLOOFK_00137 5.5e-154 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MDOLOOFK_00138 1.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MDOLOOFK_00139 3.74e-213 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MDOLOOFK_00140 7.13e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDOLOOFK_00141 8.51e-10 - - - M - - - oxidoreductase activity
MDOLOOFK_00143 5.87e-256 flp - - V - - - Beta-lactamase
MDOLOOFK_00144 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDOLOOFK_00145 1.42e-122 - - - K - - - Acetyltransferase (GNAT) domain
MDOLOOFK_00150 5.15e-135 - - - M - - - LPXTG-motif cell wall anchor domain protein
MDOLOOFK_00151 2.37e-53 - - - M - - - LPXTG-motif cell wall anchor domain protein
MDOLOOFK_00152 1.84e-61 - - - M - - - LPXTG-motif cell wall anchor domain protein
MDOLOOFK_00153 3.51e-32 - - - M - - - LPXTG-motif cell wall anchor domain protein
MDOLOOFK_00154 1.78e-218 - - - M - - - LPXTG-motif cell wall anchor domain protein
MDOLOOFK_00155 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MDOLOOFK_00156 5.48e-189 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
MDOLOOFK_00157 5.17e-129 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MDOLOOFK_00158 5.48e-204 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MDOLOOFK_00159 5.56e-246 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDOLOOFK_00160 1.44e-07 - - - S - - - YSIRK type signal peptide
MDOLOOFK_00162 3.45e-202 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MDOLOOFK_00163 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
MDOLOOFK_00164 0.0 - - - L - - - Helicase C-terminal domain protein
MDOLOOFK_00165 1.36e-260 pbpX - - V - - - Beta-lactamase
MDOLOOFK_00166 4.47e-291 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MDOLOOFK_00167 1.77e-93 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
MDOLOOFK_00169 2.16e-163 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MDOLOOFK_00170 4.02e-282 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MDOLOOFK_00171 9.02e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDOLOOFK_00172 7.99e-102 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
MDOLOOFK_00173 1.2e-41 - - - - - - - -
MDOLOOFK_00174 2.06e-112 - - - M - - - ErfK YbiS YcfS YnhG
MDOLOOFK_00175 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MDOLOOFK_00176 7.33e-218 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
MDOLOOFK_00177 2.6e-124 - - - L - - - NUDIX domain
MDOLOOFK_00178 3.74e-125 - - - - - - - -
MDOLOOFK_00179 4.56e-125 ogt 2.1.1.63 - L ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MDOLOOFK_00180 4.81e-253 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MDOLOOFK_00181 1.6e-79 ydeP - - K - - - Transcriptional regulator, HxlR family
MDOLOOFK_00182 2.68e-127 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MDOLOOFK_00184 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDOLOOFK_00185 1.08e-117 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MDOLOOFK_00186 6.15e-36 - - - - - - - -
MDOLOOFK_00187 5.31e-149 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MDOLOOFK_00188 2.39e-125 - 2.1.1.172 - J ko:K00564,ko:K10716 - ko00000,ko01000,ko02000,ko03009 Ion channel
MDOLOOFK_00189 7.2e-200 yvgN - - C - - - Aldo keto reductase
MDOLOOFK_00190 0.0 fusA1 - - J - - - elongation factor G
MDOLOOFK_00191 9.32e-185 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 haloacid dehalogenase-like hydrolase
MDOLOOFK_00192 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 AAA domain (Cdc48 subfamily)
MDOLOOFK_00193 1.36e-212 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MDOLOOFK_00194 6.27e-57 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDOLOOFK_00195 4.48e-297 - - - L - - - COG3547 Transposase and inactivated derivatives
MDOLOOFK_00196 9.22e-23 - - - S - - - Cob(I)alamin adenosyltransferase
MDOLOOFK_00197 1.57e-189 - - - S - - - Putative ABC-transporter type IV
MDOLOOFK_00199 2.33e-204 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDOLOOFK_00200 7.16e-147 - - - - - - - -
MDOLOOFK_00201 3.19e-204 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MDOLOOFK_00202 2.42e-282 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MDOLOOFK_00203 7.79e-70 - - - - - - - -
MDOLOOFK_00204 5.22e-131 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
MDOLOOFK_00205 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MDOLOOFK_00206 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MDOLOOFK_00207 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
MDOLOOFK_00208 5.93e-60 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
MDOLOOFK_00209 4.78e-42 - - - - - - - -
MDOLOOFK_00210 1.97e-66 - - - L - - - Transposase
MDOLOOFK_00211 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MDOLOOFK_00212 7.13e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MDOLOOFK_00213 3.92e-39 - - - S - - - Protein conserved in bacteria
MDOLOOFK_00214 1.09e-74 - - - - - - - -
MDOLOOFK_00215 2.99e-114 - - - - - - - -
MDOLOOFK_00216 0.0 yheS_2 - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
MDOLOOFK_00217 3.32e-121 - - - S - - - DUF218 domain
MDOLOOFK_00218 5.34e-87 - - - S - - - DUF218 domain
MDOLOOFK_00219 9.07e-143 - - - - - - - -
MDOLOOFK_00220 4.61e-138 - - - - - - - -
MDOLOOFK_00221 1.28e-106 yicL - - EG - - - EamA-like transporter family
MDOLOOFK_00222 4.04e-212 - - - EG - - - EamA-like transporter family
MDOLOOFK_00223 8.29e-202 - - - EG - - - EamA-like transporter family
MDOLOOFK_00224 4.94e-245 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDOLOOFK_00225 3.27e-229 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDOLOOFK_00226 1.6e-220 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MDOLOOFK_00227 8.77e-181 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDOLOOFK_00228 2.51e-143 - - - - - - - -
MDOLOOFK_00229 0.0 - - - S - - - O-antigen ligase like membrane protein
MDOLOOFK_00230 7.8e-57 - - - - - - - -
MDOLOOFK_00231 2.39e-121 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase homologues.
MDOLOOFK_00232 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
MDOLOOFK_00233 4.4e-215 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
MDOLOOFK_00234 1.6e-59 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
MDOLOOFK_00235 4.43e-250 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MDOLOOFK_00236 1.94e-268 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
MDOLOOFK_00237 4.15e-153 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
MDOLOOFK_00238 6.64e-315 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
MDOLOOFK_00239 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MDOLOOFK_00240 1.15e-163 - - - - - - - -
MDOLOOFK_00241 1.72e-268 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDOLOOFK_00242 1.76e-196 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDOLOOFK_00243 3.99e-200 msmF - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDOLOOFK_00244 5.73e-123 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MDOLOOFK_00245 1.13e-130 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDOLOOFK_00246 3.35e-168 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MDOLOOFK_00247 1.66e-124 - - - S - - - Domain of unknown function (DUF4811)
MDOLOOFK_00248 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
MDOLOOFK_00249 6.36e-94 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MDOLOOFK_00250 2.58e-126 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MDOLOOFK_00251 9.48e-194 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MDOLOOFK_00252 1.75e-228 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MDOLOOFK_00253 2.99e-75 cvpA - - S - - - Colicin V production protein
MDOLOOFK_00254 3.92e-123 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDOLOOFK_00255 2.02e-249 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MDOLOOFK_00256 8.67e-293 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MDOLOOFK_00257 1.13e-301 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MDOLOOFK_00258 2.53e-210 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MDOLOOFK_00259 2.61e-154 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MDOLOOFK_00260 3.84e-160 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MDOLOOFK_00261 2.37e-46 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MDOLOOFK_00262 5.97e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MDOLOOFK_00263 2.19e-100 - - - S - - - ASCH
MDOLOOFK_00264 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MDOLOOFK_00265 1.83e-190 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
MDOLOOFK_00266 1.82e-195 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MDOLOOFK_00267 4.4e-47 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDOLOOFK_00268 8.84e-238 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDOLOOFK_00269 1.2e-181 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MDOLOOFK_00270 1.95e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MDOLOOFK_00271 4.62e-92 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
MDOLOOFK_00272 2.11e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDOLOOFK_00274 1.41e-285 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
MDOLOOFK_00275 9.03e-257 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MDOLOOFK_00276 8.57e-227 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MDOLOOFK_00277 1.16e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MDOLOOFK_00278 2.46e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MDOLOOFK_00279 2.78e-251 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MDOLOOFK_00280 1.72e-153 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MDOLOOFK_00281 1.48e-30 dltr - - K - - - response regulator
MDOLOOFK_00282 3.72e-300 sptS - - T - - - Histidine kinase
MDOLOOFK_00283 8.2e-268 - - - EGP - - - Major Facilitator Superfamily
MDOLOOFK_00284 1.59e-90 - - - O - - - OsmC-like protein
MDOLOOFK_00285 1.48e-14 - - - - - - - -
MDOLOOFK_00286 6.39e-32 - - - S - - - transposase or invertase
MDOLOOFK_00287 1.66e-309 slpX - - S - - - SLAP domain
MDOLOOFK_00288 3e-186 - - - K - - - SIS domain
MDOLOOFK_00289 9.15e-122 - 2.7.11.1, 3.2.1.8 - M ko:K01181,ko:K03832,ko:K08884 - ko00000,ko01000,ko01001,ko02000 energy transducer activity
MDOLOOFK_00290 1.35e-30 - - - - - - - -
MDOLOOFK_00291 1.91e-82 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
MDOLOOFK_00292 1.2e-279 - - - L ko:K07484 - ko00000 Transposase IS66 family
MDOLOOFK_00293 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MDOLOOFK_00294 5.9e-191 glvR - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
MDOLOOFK_00295 1.52e-103 - - - - - - - -
MDOLOOFK_00296 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
MDOLOOFK_00297 5.51e-46 - - - C - - - Heavy-metal-associated domain
MDOLOOFK_00298 8.01e-125 dpsB - - P - - - Belongs to the Dps family
MDOLOOFK_00299 3.28e-179 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MDOLOOFK_00300 7.82e-311 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MDOLOOFK_00301 4.41e-220 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MDOLOOFK_00302 6.28e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MDOLOOFK_00303 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MDOLOOFK_00304 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDOLOOFK_00305 5.66e-112 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
MDOLOOFK_00306 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MDOLOOFK_00307 5.23e-172 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MDOLOOFK_00308 1.77e-262 - - - M - - - Glycosyl transferases group 1
MDOLOOFK_00309 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MDOLOOFK_00310 6.65e-196 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MDOLOOFK_00311 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MDOLOOFK_00312 5.3e-286 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MDOLOOFK_00313 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MDOLOOFK_00314 2.33e-174 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
MDOLOOFK_00315 1.14e-152 - - - S - - - Putative esterase
MDOLOOFK_00316 1.81e-270 - 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDOLOOFK_00317 2.36e-180 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
MDOLOOFK_00318 1.46e-31 - - - - - - - -
MDOLOOFK_00319 4.27e-188 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
MDOLOOFK_00320 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MDOLOOFK_00321 4.42e-124 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
MDOLOOFK_00322 2.43e-100 yybA - - K - - - Transcriptional regulator
MDOLOOFK_00323 4.7e-125 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MDOLOOFK_00324 7.16e-132 - - - S - - - Peptidase propeptide and YPEB domain
MDOLOOFK_00325 7.04e-115 ykoJ - - S - - - Peptidase propeptide and YPEB domain
MDOLOOFK_00326 1.86e-203 - - - T - - - GHKL domain
MDOLOOFK_00327 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
MDOLOOFK_00328 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MDOLOOFK_00329 1.14e-159 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDOLOOFK_00330 1.82e-192 - - - - - - - -
MDOLOOFK_00332 4.84e-124 - - - M - - - Glycosyl transferase
MDOLOOFK_00333 2.26e-177 - - - M - - - Glycosyl transferase
MDOLOOFK_00334 6.98e-241 - - - G - - - Glycosyl hydrolases family 8
MDOLOOFK_00335 3.01e-178 - 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
MDOLOOFK_00336 1.33e-202 isdF - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDOLOOFK_00337 2.94e-203 isdE - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MDOLOOFK_00338 1.24e-112 - - - M ko:K14193 ko05150,map05150 ko00000,ko00001 Iron Transport-associated domain
MDOLOOFK_00339 1.11e-253 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
MDOLOOFK_00340 4.39e-268 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
MDOLOOFK_00342 4.64e-53 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
MDOLOOFK_00343 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
MDOLOOFK_00344 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MDOLOOFK_00345 7.76e-40 - - - S - - - ABC-2 family transporter protein
MDOLOOFK_00346 3.25e-165 - - - K - - - helix_turn_helix, mercury resistance
MDOLOOFK_00347 5.67e-296 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MDOLOOFK_00348 3.69e-54 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
MDOLOOFK_00349 5.74e-96 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
MDOLOOFK_00350 0.0 - - - - - - - -
MDOLOOFK_00351 1.35e-240 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
MDOLOOFK_00352 0.0 yhaN - - L - - - AAA domain
MDOLOOFK_00353 4.13e-296 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
MDOLOOFK_00354 8.43e-73 yheA - - S - - - Belongs to the UPF0342 family
MDOLOOFK_00355 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MDOLOOFK_00356 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDOLOOFK_00357 1.12e-85 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MDOLOOFK_00358 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDOLOOFK_00359 3.09e-159 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MDOLOOFK_00360 2.22e-78 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
MDOLOOFK_00361 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
MDOLOOFK_00362 1.37e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MDOLOOFK_00363 4.18e-128 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MDOLOOFK_00364 1.74e-224 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
MDOLOOFK_00365 3.75e-93 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
MDOLOOFK_00366 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
MDOLOOFK_00367 4.53e-29 - - - C - - - Flavodoxin
MDOLOOFK_00368 4.83e-62 - - - C - - - Flavodoxin
MDOLOOFK_00369 3.49e-269 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MDOLOOFK_00370 1.29e-231 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MDOLOOFK_00371 3.14e-147 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MDOLOOFK_00372 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MDOLOOFK_00373 1.88e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MDOLOOFK_00374 5.26e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
MDOLOOFK_00375 3.55e-116 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
MDOLOOFK_00376 5.93e-167 terC - - P - - - Integral membrane protein TerC family
MDOLOOFK_00377 1.54e-84 yeaO - - S - - - Protein of unknown function, DUF488
MDOLOOFK_00378 1.56e-148 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MDOLOOFK_00379 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MDOLOOFK_00380 1.43e-162 csrR - - K - - - response regulator
MDOLOOFK_00381 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MDOLOOFK_00382 8.55e-99 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MDOLOOFK_00383 1.56e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDOLOOFK_00384 1.39e-197 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MDOLOOFK_00385 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDOLOOFK_00386 2.5e-278 - - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MDOLOOFK_00387 7.31e-269 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDOLOOFK_00388 1.55e-148 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
MDOLOOFK_00389 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MDOLOOFK_00390 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MDOLOOFK_00391 3.34e-134 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
MDOLOOFK_00392 0.0 - - - S - - - membrane
MDOLOOFK_00393 8.86e-89 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
MDOLOOFK_00394 2.78e-68 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
MDOLOOFK_00395 1.23e-190 yycI - - S - - - YycH protein
MDOLOOFK_00396 9.31e-264 yycH - - S - - - YycH protein
MDOLOOFK_00398 3.65e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MDOLOOFK_00399 7.42e-123 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MDOLOOFK_00400 5.24e-191 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MDOLOOFK_00401 1.19e-174 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MDOLOOFK_00402 4.08e-270 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MDOLOOFK_00403 4.36e-142 XK27_00160 - - S - - - Domain of unknown function (DUF5052)
MDOLOOFK_00404 1.23e-89 - - - - - - - -
MDOLOOFK_00405 3.09e-125 - - - S - - - Protein of unknown function (DUF2974)
MDOLOOFK_00406 5.32e-148 - - - L - - - Resolvase, N-terminal
MDOLOOFK_00407 0.0 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
MDOLOOFK_00408 1.53e-213 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MDOLOOFK_00409 1.4e-208 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MDOLOOFK_00410 2.45e-211 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
MDOLOOFK_00411 1.11e-95 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MDOLOOFK_00412 1.76e-52 - - - - - - - -
MDOLOOFK_00413 7.48e-155 - - - C - - - nitroreductase
MDOLOOFK_00414 7.9e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MDOLOOFK_00415 0.0 mdr - - EGP - - - Major Facilitator
MDOLOOFK_00416 7.97e-70 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MDOLOOFK_00417 5.09e-120 bbsF_1 2.8.3.19 - C ko:K18702 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MDOLOOFK_00418 4.41e-208 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MDOLOOFK_00419 1.77e-222 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MDOLOOFK_00420 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
MDOLOOFK_00421 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MDOLOOFK_00422 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MDOLOOFK_00423 3.91e-136 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
MDOLOOFK_00424 6.48e-104 - - - K - - - Acetyltransferase (GNAT) domain
MDOLOOFK_00425 2.29e-204 - - - M - - - Belongs to the glycosyl hydrolase 28 family
MDOLOOFK_00426 5.61e-70 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
MDOLOOFK_00427 2.7e-199 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MDOLOOFK_00428 1.6e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
MDOLOOFK_00429 3.38e-139 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MDOLOOFK_00430 6.39e-17 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MDOLOOFK_00431 3.14e-29 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MDOLOOFK_00432 1.17e-199 cinI - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
MDOLOOFK_00433 0.0 - - - S - - - Predicted membrane protein (DUF2207)
MDOLOOFK_00434 3.77e-175 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MDOLOOFK_00435 1.39e-178 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MDOLOOFK_00436 1.49e-291 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MDOLOOFK_00437 4.51e-189 - - - S - - - haloacid dehalogenase-like hydrolase
MDOLOOFK_00438 5.62e-50 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
MDOLOOFK_00439 3.58e-111 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
MDOLOOFK_00440 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
MDOLOOFK_00441 2.57e-159 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MDOLOOFK_00442 5.75e-72 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
MDOLOOFK_00443 1.98e-120 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
MDOLOOFK_00444 1.26e-223 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
MDOLOOFK_00445 1.71e-182 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
MDOLOOFK_00446 1e-207 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Beta-lactamase
MDOLOOFK_00447 7.17e-146 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
MDOLOOFK_00448 3.02e-209 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MDOLOOFK_00449 9.33e-163 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MDOLOOFK_00450 6.34e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MDOLOOFK_00451 6.64e-146 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MDOLOOFK_00452 4.68e-138 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MDOLOOFK_00453 1.14e-63 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MDOLOOFK_00454 4.01e-198 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MDOLOOFK_00455 1.14e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MDOLOOFK_00456 9.07e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MDOLOOFK_00457 8.7e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MDOLOOFK_00458 1.66e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MDOLOOFK_00459 1.45e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MDOLOOFK_00460 1.56e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MDOLOOFK_00461 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MDOLOOFK_00462 3.03e-44 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MDOLOOFK_00463 1.23e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MDOLOOFK_00464 1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDOLOOFK_00465 7.94e-90 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MDOLOOFK_00466 7.18e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MDOLOOFK_00467 4.84e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MDOLOOFK_00468 1.07e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MDOLOOFK_00469 2.22e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MDOLOOFK_00470 4.95e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MDOLOOFK_00471 3.35e-270 - - - - - - - -
MDOLOOFK_00472 2.3e-175 - - - S - - - SLAP domain
MDOLOOFK_00473 0.0 eriC - - P ko:K03281 - ko00000 chloride
MDOLOOFK_00474 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MDOLOOFK_00475 1.03e-120 - - - - - - - -
MDOLOOFK_00476 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MDOLOOFK_00477 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MDOLOOFK_00478 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MDOLOOFK_00479 3.37e-192 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDOLOOFK_00480 1.87e-81 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MDOLOOFK_00481 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
MDOLOOFK_00482 1.83e-316 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MDOLOOFK_00483 3.3e-244 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MDOLOOFK_00484 1.13e-48 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
MDOLOOFK_00485 1.79e-268 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MDOLOOFK_00486 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDOLOOFK_00487 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDOLOOFK_00488 1.93e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MDOLOOFK_00489 7.46e-108 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MDOLOOFK_00490 1.89e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MDOLOOFK_00491 1.98e-115 - - - E - - - Zn peptidase
MDOLOOFK_00492 8.87e-54 - - - K - - - Helix-turn-helix XRE-family like proteins
MDOLOOFK_00493 9.21e-56 - - - - - - - -
MDOLOOFK_00494 9.45e-219 - - - S - - - Bacteriocin helveticin-J
MDOLOOFK_00495 1.84e-197 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MDOLOOFK_00496 3.02e-170 gntR - - K - - - UbiC transcription regulator-associated domain protein
MDOLOOFK_00497 7.39e-225 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
MDOLOOFK_00498 1.14e-98 - - - M - - - LPXTG-motif cell wall anchor domain protein
MDOLOOFK_00499 9.42e-267 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MDOLOOFK_00500 1.18e-229 - - - L ko:K07478 - ko00000 AAA C-terminal domain
MDOLOOFK_00501 1.69e-279 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MDOLOOFK_00502 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MDOLOOFK_00503 6.51e-194 - - - S - - - COG0433 Predicted ATPase
MDOLOOFK_00505 7.32e-48 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MDOLOOFK_00506 1.46e-56 - - - - - - - -
MDOLOOFK_00507 6.6e-14 - - - - - - - -
MDOLOOFK_00508 1.35e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
MDOLOOFK_00509 1.43e-176 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
MDOLOOFK_00510 4.91e-79 - - - M - - - LPXTG-motif cell wall anchor domain protein
MDOLOOFK_00511 1.1e-06 - - - Q - - - Signal peptide protein, YSIRK family
MDOLOOFK_00512 9.17e-50 - - - P - - - NhaP-type Na H and K H
MDOLOOFK_00513 9.85e-49 yozE - - S - - - Belongs to the UPF0346 family
MDOLOOFK_00514 8.83e-187 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
MDOLOOFK_00515 1.03e-210 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MDOLOOFK_00516 1.63e-152 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MDOLOOFK_00517 1.59e-172 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MDOLOOFK_00518 3.54e-95 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MDOLOOFK_00519 2.32e-99 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDOLOOFK_00520 1.43e-144 - - - - - - - -
MDOLOOFK_00522 2.02e-144 - - - E - - - Belongs to the SOS response-associated peptidase family
MDOLOOFK_00523 2.89e-193 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MDOLOOFK_00524 8.39e-151 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
MDOLOOFK_00525 2.15e-137 - - - S - - - Protein of unknown function (DUF1461)
MDOLOOFK_00526 3.16e-184 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MDOLOOFK_00527 6.48e-136 yutD - - S - - - Protein of unknown function (DUF1027)
MDOLOOFK_00528 0.0 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MDOLOOFK_00529 9.89e-74 - - - - - - - -
MDOLOOFK_00530 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MDOLOOFK_00531 8.69e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MDOLOOFK_00532 1.13e-272 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MDOLOOFK_00533 3.09e-71 - - - - - - - -
MDOLOOFK_00534 2.96e-23 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MDOLOOFK_00535 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MDOLOOFK_00536 2.48e-78 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MDOLOOFK_00537 1.82e-05 - - - - - - - -
MDOLOOFK_00538 2.01e-230 - - - M - - - Rib/alpha-like repeat
MDOLOOFK_00539 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
MDOLOOFK_00540 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MDOLOOFK_00541 7.24e-58 - - - - - - - -
MDOLOOFK_00542 9.26e-218 - - - GK - - - ROK family
MDOLOOFK_00543 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
MDOLOOFK_00544 1.15e-104 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MDOLOOFK_00545 1.04e-39 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MDOLOOFK_00546 2.18e-13 - - - L - - - Psort location Cytoplasmic, score
MDOLOOFK_00547 5.66e-16 - - - L - - - Transposase and inactivated derivatives, IS30 family
MDOLOOFK_00548 9.25e-81 - - - L - - - Transposase and inactivated derivatives, IS30 family
MDOLOOFK_00549 2.86e-287 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MDOLOOFK_00550 9.02e-275 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MDOLOOFK_00551 6.51e-301 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MDOLOOFK_00552 6.26e-291 - - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MDOLOOFK_00553 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MDOLOOFK_00554 2.59e-253 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MDOLOOFK_00555 2.88e-183 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MDOLOOFK_00556 2.6e-177 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MDOLOOFK_00557 1.22e-121 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MDOLOOFK_00558 5.86e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MDOLOOFK_00559 1.02e-234 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MDOLOOFK_00560 2.21e-180 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MDOLOOFK_00561 1.87e-247 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
MDOLOOFK_00562 3.06e-163 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MDOLOOFK_00563 2.77e-114 - - - K - - - GNAT family
MDOLOOFK_00564 5.48e-260 XK27_00915 - - C - - - Luciferase-like monooxygenase
MDOLOOFK_00565 1.56e-157 - - - L - - - This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MDOLOOFK_00566 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MDOLOOFK_00567 3.58e-61 - - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
MDOLOOFK_00568 8.36e-54 - - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
MDOLOOFK_00569 6.03e-123 yneE - - K - - - Transcriptional regulator
MDOLOOFK_00570 9.51e-81 yneE - - K - - - Transcriptional regulator
MDOLOOFK_00571 8.69e-192 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MDOLOOFK_00572 7.35e-307 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MDOLOOFK_00573 4.2e-249 pbpX1 - - V - - - Beta-lactamase
MDOLOOFK_00574 0.0 - - - I - - - Protein of unknown function (DUF2974)
MDOLOOFK_00575 9.69e-25 - - - - - - - -
MDOLOOFK_00576 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
MDOLOOFK_00577 6.75e-92 - - - S - - - Iron-sulphur cluster biosynthesis
MDOLOOFK_00579 1.06e-294 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MDOLOOFK_00580 9.07e-197 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MDOLOOFK_00581 9.1e-315 yifK - - E ko:K03293 - ko00000 Amino acid permease
MDOLOOFK_00582 4.48e-173 - - - S - - - PFAM Archaeal ATPase
MDOLOOFK_00583 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
MDOLOOFK_00584 4.52e-202 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MDOLOOFK_00585 8.21e-215 ldh3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
MDOLOOFK_00586 2.55e-94 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDOLOOFK_00587 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDOLOOFK_00588 3.39e-253 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MDOLOOFK_00589 9.94e-209 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MDOLOOFK_00590 1.83e-146 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MDOLOOFK_00591 5.01e-151 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
MDOLOOFK_00592 1.88e-144 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
MDOLOOFK_00593 0.0 snf - - KL - - - domain protein
MDOLOOFK_00594 3.61e-38 snf - - KL - - - domain protein
MDOLOOFK_00595 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MDOLOOFK_00596 6.18e-181 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
MDOLOOFK_00598 2.71e-235 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MDOLOOFK_00599 0.0 - - - L - - - Nuclease-related domain
MDOLOOFK_00600 2.58e-98 - - - S - - - Protein of unknown function (DUF3021)
MDOLOOFK_00601 5.83e-100 - - - K - - - LytTr DNA-binding domain
MDOLOOFK_00602 6.41e-118 - - - - - - - -
MDOLOOFK_00603 7.77e-141 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
MDOLOOFK_00604 0.0 mutS1 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MDOLOOFK_00605 8.25e-58 - - - L - - - PLD-like domain
MDOLOOFK_00606 0.0 - - - L - - - PLD-like domain
MDOLOOFK_00607 1.51e-117 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDOLOOFK_00608 1.66e-303 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
MDOLOOFK_00609 4.8e-38 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDOLOOFK_00611 1.88e-166 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MDOLOOFK_00612 1.05e-165 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
MDOLOOFK_00613 2.91e-191 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MDOLOOFK_00614 4.99e-178 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
MDOLOOFK_00615 1.05e-197 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MDOLOOFK_00616 9.07e-59 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
MDOLOOFK_00617 6.88e-257 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MDOLOOFK_00618 1.08e-173 - - - S - - - Protein of unknown function (DUF1129)
MDOLOOFK_00619 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
MDOLOOFK_00620 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
MDOLOOFK_00622 0.0 - - - - - - - -
MDOLOOFK_00623 5.06e-111 - - - - - - - -
MDOLOOFK_00624 6.33e-27 potE - - E - - - Amino Acid
MDOLOOFK_00625 1.79e-113 potE - - E - - - Amino acid permease
MDOLOOFK_00626 6.25e-246 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MDOLOOFK_00627 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MDOLOOFK_00628 2.29e-74 - - - E - - - amino acid
MDOLOOFK_00629 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
MDOLOOFK_00630 4.7e-163 pgm - - G - - - Phosphoglycerate mutase family
MDOLOOFK_00631 2.31e-148 - - - S - - - repeat protein
MDOLOOFK_00632 3.36e-225 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
MDOLOOFK_00633 1.07e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
MDOLOOFK_00634 7.47e-152 - - - S - - - Haloacid dehalogenase-like hydrolase
MDOLOOFK_00635 2.35e-310 ycaM - - E - - - amino acid
MDOLOOFK_00636 3.01e-180 - - - S - - - Cysteine-rich secretory protein family
MDOLOOFK_00637 9.43e-313 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MDOLOOFK_00638 2.68e-67 - - - L - - - Plasmid pRiA4b ORF-3-like protein
MDOLOOFK_00639 4.67e-58 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
MDOLOOFK_00640 1.09e-259 lacG 3.2.1.21, 3.2.1.85 - G ko:K01220,ko:K05350 ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MDOLOOFK_00641 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
MDOLOOFK_00642 1.47e-201 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MDOLOOFK_00643 2.88e-80 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MDOLOOFK_00644 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MDOLOOFK_00645 1.61e-64 ylxQ - - J - - - ribosomal protein
MDOLOOFK_00646 3.75e-63 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
MDOLOOFK_00647 8.73e-262 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MDOLOOFK_00648 1.97e-107 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MDOLOOFK_00649 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDOLOOFK_00650 7.25e-117 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
MDOLOOFK_00651 1.13e-149 - - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MDOLOOFK_00652 1.21e-43 - - - K - - - MerR HTH family regulatory protein
MDOLOOFK_00653 5.57e-59 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
MDOLOOFK_00654 4.45e-83 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MDOLOOFK_00655 5.19e-138 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
MDOLOOFK_00656 5.46e-126 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MDOLOOFK_00657 9.86e-146 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MDOLOOFK_00658 3.05e-188 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MDOLOOFK_00659 6.91e-156 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
MDOLOOFK_00660 2.86e-244 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MDOLOOFK_00661 1.65e-241 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
MDOLOOFK_00664 2.85e-149 blpT - - - - - - -
MDOLOOFK_00665 2.24e-146 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
MDOLOOFK_00666 5.46e-163 - - - M - - - LPXTG-motif cell wall anchor domain protein
MDOLOOFK_00667 5.23e-47 yebC - - M - - - Membrane
MDOLOOFK_00668 1.95e-126 - - - S - - - response to antibiotic
MDOLOOFK_00669 1.72e-20 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
MDOLOOFK_00670 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MDOLOOFK_00671 1.81e-128 - - - G - - - Aldose 1-epimerase
MDOLOOFK_00672 1.29e-170 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDOLOOFK_00673 5.76e-148 - - - - - - - -
MDOLOOFK_00674 8.4e-170 - - - - - - - -
MDOLOOFK_00675 1.38e-206 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MDOLOOFK_00676 3.5e-138 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MDOLOOFK_00677 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
MDOLOOFK_00678 1.04e-231 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
MDOLOOFK_00679 5.14e-287 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MDOLOOFK_00680 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MDOLOOFK_00681 5.26e-171 - - - H - - - Aldolase/RraA
MDOLOOFK_00682 2.66e-187 gyaR 1.1.1.26, 1.1.1.399, 1.1.1.95 - CH ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDOLOOFK_00683 3.84e-95 yhdG - - E ko:K03294 - ko00000 Amino Acid
MDOLOOFK_00684 1.1e-201 yhdG - - E ko:K03294 - ko00000 Amino Acid
MDOLOOFK_00685 1.33e-56 - - - E - - - Pfam:DUF955
MDOLOOFK_00687 5.88e-91 yslB - - S - - - Protein of unknown function (DUF2507)
MDOLOOFK_00688 5.02e-187 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MDOLOOFK_00689 5.72e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MDOLOOFK_00690 3.03e-92 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MDOLOOFK_00691 6.16e-179 - - - EGP - - - Major Facilitator Superfamily
MDOLOOFK_00692 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MDOLOOFK_00694 3.65e-109 - - - M - - - NlpC/P60 family
MDOLOOFK_00695 1.84e-169 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
MDOLOOFK_00697 7.25e-88 - - - L - - - RelB antitoxin
MDOLOOFK_00698 2.86e-118 - - - F - - - Nucleoside 2-deoxyribosyltransferase
MDOLOOFK_00699 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MDOLOOFK_00700 9.69e-184 - - - P - - - Voltage gated chloride channel
MDOLOOFK_00701 1.64e-236 - - - C - - - FMN-dependent dehydrogenase
MDOLOOFK_00702 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MDOLOOFK_00703 6.87e-172 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MDOLOOFK_00704 9.49e-302 ymfH - - S - - - Peptidase M16
MDOLOOFK_00705 2.43e-283 ymfF - - S - - - Peptidase M16 inactive domain protein
MDOLOOFK_00706 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MDOLOOFK_00707 3.12e-91 - - - S - - - Protein of unknown function (DUF1149)
MDOLOOFK_00708 2.12e-136 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MDOLOOFK_00709 2.19e-270 XK27_05220 - - S - - - AI-2E family transporter
MDOLOOFK_00710 1.99e-87 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MDOLOOFK_00711 5.18e-222 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
MDOLOOFK_00712 2.45e-146 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MDOLOOFK_00713 8.36e-75 - - - K - - - Helix-turn-helix domain
MDOLOOFK_00714 5.14e-105 ykuP - - C ko:K03839 - ko00000 Flavodoxin
MDOLOOFK_00715 3.7e-113 gtcA1 - - S - - - Teichoic acid glycosylation protein
MDOLOOFK_00716 2.17e-261 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MDOLOOFK_00717 2.18e-190 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
MDOLOOFK_00718 7.4e-295 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MDOLOOFK_00719 4.29e-148 eriC - - P ko:K03281 - ko00000 chloride
MDOLOOFK_00720 6.55e-76 eriC - - P ko:K03281 - ko00000 chloride
MDOLOOFK_00721 3.78e-44 - - - K - - - FCD
MDOLOOFK_00722 1.19e-11 - - - K - - - FCD
MDOLOOFK_00723 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MDOLOOFK_00724 2.92e-192 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MDOLOOFK_00725 4.27e-155 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MDOLOOFK_00726 1.48e-258 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MDOLOOFK_00727 1.65e-101 - - - - - - - -
MDOLOOFK_00728 2.79e-226 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDOLOOFK_00729 3.7e-40 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
MDOLOOFK_00730 3.19e-76 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
MDOLOOFK_00731 8.96e-160 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MDOLOOFK_00732 1.17e-155 - - - - - - - -
MDOLOOFK_00733 5.43e-114 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MDOLOOFK_00734 1.68e-276 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
MDOLOOFK_00735 2.43e-203 - - - I - - - alpha/beta hydrolase fold
MDOLOOFK_00736 9.09e-166 yibF - - S - - - overlaps another CDS with the same product name
MDOLOOFK_00737 3.98e-257 yibE - - S - - - overlaps another CDS with the same product name
MDOLOOFK_00738 4.23e-165 - - - - - - - -
MDOLOOFK_00739 1.46e-264 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MDOLOOFK_00740 4.45e-292 - - - S - - - Cysteine-rich secretory protein family
MDOLOOFK_00741 1.23e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MDOLOOFK_00742 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MDOLOOFK_00743 2.45e-47 - - - L - - - Transposase and inactivated derivatives, IS30 family
MDOLOOFK_00744 2.76e-83 - - - - - - - -
MDOLOOFK_00745 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
MDOLOOFK_00746 1.01e-12 - - - - - - - -
MDOLOOFK_00747 1.19e-88 - - - - - - - -
MDOLOOFK_00748 1.92e-34 - - - - - - - -
MDOLOOFK_00749 6.32e-42 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
MDOLOOFK_00750 5.77e-108 - - - - - - - -
MDOLOOFK_00751 5.76e-220 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MDOLOOFK_00752 7.71e-133 - - - L - - - Integrase
MDOLOOFK_00753 3.4e-196 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MDOLOOFK_00754 3.87e-73 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MDOLOOFK_00755 3.46e-159 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
MDOLOOFK_00756 4.11e-294 - - - Q - - - Imidazolonepropionase and related amidohydrolases
MDOLOOFK_00757 3.54e-94 - - - K ko:K03492 - ko00000,ko03000 UTRA domain
MDOLOOFK_00758 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MDOLOOFK_00759 2.82e-133 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
MDOLOOFK_00760 4.43e-06 - - - M - - - LPXTG-motif cell wall anchor domain protein
MDOLOOFK_00761 3e-108 - - - - - - - -
MDOLOOFK_00762 0.0 - - - S - - - Calcineurin-like phosphoesterase
MDOLOOFK_00763 1.61e-70 - - - - - - - -
MDOLOOFK_00764 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDOLOOFK_00765 1.7e-201 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
MDOLOOFK_00766 1.64e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MDOLOOFK_00767 5.46e-233 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
MDOLOOFK_00768 5.86e-114 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
MDOLOOFK_00769 1.51e-127 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MDOLOOFK_00770 1.71e-209 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
MDOLOOFK_00771 3.58e-263 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MDOLOOFK_00772 9.56e-177 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MDOLOOFK_00773 2.6e-170 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MDOLOOFK_00774 3.32e-264 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MDOLOOFK_00775 1.29e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
MDOLOOFK_00776 2.49e-101 - - - L ko:K07482 - ko00000 Helix-turn-helix domain
MDOLOOFK_00777 1.44e-64 - - - L ko:K07482 - ko00000 Helix-turn-helix domain
MDOLOOFK_00778 8.26e-24 - - - D - - - Domain of Unknown Function (DUF1542)
MDOLOOFK_00779 3.5e-101 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MDOLOOFK_00780 4.13e-76 - - - K - - - Helix-turn-helix XRE-family like proteins
MDOLOOFK_00781 2.86e-286 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MDOLOOFK_00782 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MDOLOOFK_00783 1.16e-88 - - - - - - - -
MDOLOOFK_00785 5.75e-227 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MDOLOOFK_00786 1.36e-62 - - - - - - - -
MDOLOOFK_00787 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MDOLOOFK_00788 2.14e-103 - - - - - - - -
MDOLOOFK_00789 8.66e-166 - - - - - - - -
MDOLOOFK_00790 2.77e-10 - - - - - - - -
MDOLOOFK_00791 1.1e-272 - - - M - - - Glycosyl transferase
MDOLOOFK_00792 3.15e-226 - - - G - - - Glycosyl hydrolases family 8
MDOLOOFK_00793 2e-157 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
MDOLOOFK_00794 1.99e-203 - - - L - - - HNH nucleases
MDOLOOFK_00795 3.92e-185 yhaH - - S - - - Protein of unknown function (DUF805)
MDOLOOFK_00796 7.11e-174 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MDOLOOFK_00797 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MDOLOOFK_00798 1.68e-166 - - - T - - - Transcriptional regulatory protein, C terminal
MDOLOOFK_00799 1.28e-228 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MDOLOOFK_00800 0.0 - - - V - - - ABC transporter transmembrane region
MDOLOOFK_00801 2.46e-170 - - - S - - - PAS domain
MDOLOOFK_00803 2.82e-182 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
MDOLOOFK_00804 1.3e-94 - - - S - - - Protein of unknown function (DUF3290)
MDOLOOFK_00805 2.23e-150 yviA - - S - - - Protein of unknown function (DUF421)
MDOLOOFK_00806 1.46e-202 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MDOLOOFK_00807 2.7e-232 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
MDOLOOFK_00808 7.24e-204 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
MDOLOOFK_00809 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MDOLOOFK_00810 5.26e-259 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
MDOLOOFK_00811 1.64e-202 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
MDOLOOFK_00812 5.62e-187 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDOLOOFK_00813 0.0 - - - S - - - Zn-dependent metallo-hydrolase RNA specificity domain
MDOLOOFK_00814 2.47e-309 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MDOLOOFK_00815 4.01e-207 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MDOLOOFK_00816 2.3e-206 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
MDOLOOFK_00817 1.53e-127 yobS - - K - - - Bacterial regulatory proteins, tetR family
MDOLOOFK_00818 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
MDOLOOFK_00825 5.22e-45 ykzG - - S - - - Belongs to the UPF0356 family
MDOLOOFK_00826 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDOLOOFK_00827 1.94e-298 - - - S - - - Domain of unknown function (DUF4838)
MDOLOOFK_00830 1.72e-13 - - - - - - - -
MDOLOOFK_00831 1.85e-266 - - - S - - - CAAX protease self-immunity
MDOLOOFK_00832 1.74e-185 - - - S - - - Replication initiation factor
MDOLOOFK_00833 2.67e-180 - - - D - - - Ftsk spoiiie family protein
MDOLOOFK_00834 2.74e-10 - - - - - - - -
MDOLOOFK_00835 1.17e-172 - - - S - - - PFAM Archaeal ATPase
MDOLOOFK_00836 1.46e-199 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
MDOLOOFK_00837 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MDOLOOFK_00838 5.74e-260 - - - S - - - ABC transporter
MDOLOOFK_00839 1.55e-122 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MDOLOOFK_00840 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MDOLOOFK_00841 3.19e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MDOLOOFK_00842 1.02e-27 - - - - - - - -
MDOLOOFK_00843 3.54e-230 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MDOLOOFK_00844 4.2e-205 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MDOLOOFK_00845 5.73e-240 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MDOLOOFK_00846 3.42e-232 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MDOLOOFK_00847 1.65e-285 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
MDOLOOFK_00848 1.73e-258 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
MDOLOOFK_00849 1.87e-44 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MDOLOOFK_00850 2.25e-137 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
MDOLOOFK_00851 0.0 sufI - - Q - - - Multicopper oxidase
MDOLOOFK_00852 1.05e-33 - - - - - - - -
MDOLOOFK_00853 0.0 - - - - - - - -
MDOLOOFK_00855 3.94e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MDOLOOFK_00856 1.13e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MDOLOOFK_00857 7.35e-145 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDOLOOFK_00858 1.84e-261 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MDOLOOFK_00859 8.4e-62 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
MDOLOOFK_00860 4.97e-22 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
MDOLOOFK_00861 3.41e-160 - - - K - - - Bacterial regulatory proteins, tetR family
MDOLOOFK_00862 1.11e-177 - - - - - - - -
MDOLOOFK_00863 2.83e-295 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MDOLOOFK_00864 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MDOLOOFK_00865 5.89e-314 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MDOLOOFK_00866 1.11e-69 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MDOLOOFK_00867 1.5e-33 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MDOLOOFK_00868 1.15e-280 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MDOLOOFK_00869 3.66e-225 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MDOLOOFK_00870 6.89e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MDOLOOFK_00871 4.67e-279 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MDOLOOFK_00872 8.47e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MDOLOOFK_00874 2.81e-18 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
MDOLOOFK_00875 2.02e-23 - - - S - - - Transposase C of IS166 homeodomain
MDOLOOFK_00876 8.31e-228 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
MDOLOOFK_00877 5.54e-69 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MDOLOOFK_00878 1.26e-46 - - - S - - - Protein of unknown function (DUF2969)
MDOLOOFK_00879 1.96e-153 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MDOLOOFK_00880 2.7e-89 - - - K - - - Helix-turn-helix domain, rpiR family
MDOLOOFK_00881 6.43e-167 - - - F - - - glutamine amidotransferase
MDOLOOFK_00882 2.49e-189 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MDOLOOFK_00883 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MDOLOOFK_00884 5.82e-25 lysM - - M - - - LysM domain
MDOLOOFK_00893 2.64e-34 - - - L - - - four-way junction helicase activity
MDOLOOFK_00894 1.72e-22 - - - L - - - Psort location Cytoplasmic, score
MDOLOOFK_00895 0.0 - - - S ko:K06921 - ko00000 Archaea bacterial proteins of unknown function
MDOLOOFK_00896 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MDOLOOFK_00897 4.33e-75 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
MDOLOOFK_00898 1.27e-272 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
MDOLOOFK_00899 2.06e-51 ynzC - - S - - - UPF0291 protein
MDOLOOFK_00900 6.43e-41 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
MDOLOOFK_00901 3.26e-200 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MDOLOOFK_00902 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MDOLOOFK_00903 2.72e-197 supH - - S - - - haloacid dehalogenase-like hydrolase
MDOLOOFK_00904 4.33e-69 - - - - - - - -
MDOLOOFK_00905 8.51e-50 - - - - - - - -
MDOLOOFK_00906 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
MDOLOOFK_00907 3.07e-202 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MDOLOOFK_00908 8.97e-47 - - - - - - - -
MDOLOOFK_00909 3.88e-40 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative DNA-binding domain
MDOLOOFK_00910 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
MDOLOOFK_00911 1.82e-276 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
MDOLOOFK_00912 0.0 - - - S - - - C4-dicarboxylate anaerobic carrier
MDOLOOFK_00913 3.23e-174 - - - - - - - -
MDOLOOFK_00914 4.81e-76 - - - S - - - Antibiotic biosynthesis monooxygenase
MDOLOOFK_00915 4.85e-97 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MDOLOOFK_00916 6.19e-284 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MDOLOOFK_00917 3.79e-106 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
MDOLOOFK_00918 8.38e-103 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
MDOLOOFK_00919 1.21e-229 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MDOLOOFK_00920 3.94e-291 - - - L - - - COG3547 Transposase and inactivated derivatives
MDOLOOFK_00921 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDOLOOFK_00922 1.38e-180 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MDOLOOFK_00923 1.89e-172 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDOLOOFK_00924 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
MDOLOOFK_00925 9.55e-82 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MDOLOOFK_00926 2.81e-315 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
MDOLOOFK_00927 4.55e-131 - - - S - - - Peptidase propeptide and YPEB domain
MDOLOOFK_00929 5.16e-135 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDOLOOFK_00930 4.98e-221 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MDOLOOFK_00931 1.54e-124 - - - E - - - GDSL-like Lipase/Acylhydrolase
MDOLOOFK_00932 1.16e-97 yjcF - - S - - - Acetyltransferase (GNAT) domain
MDOLOOFK_00933 8.63e-185 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MDOLOOFK_00934 2.92e-137 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
MDOLOOFK_00935 4.64e-143 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MDOLOOFK_00936 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MDOLOOFK_00937 3.76e-64 arbZ - - I - - - Phosphate acyltransferases
MDOLOOFK_00938 7.64e-110 arbZ - - I - - - Phosphate acyltransferases
MDOLOOFK_00939 3.37e-50 - - - S - - - Cytochrome B5
MDOLOOFK_00940 0.0 qacA - - EGP - - - Major Facilitator
MDOLOOFK_00941 5.54e-311 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MDOLOOFK_00942 2.96e-100 - - - K - - - DNA-templated transcription, initiation
MDOLOOFK_00944 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MDOLOOFK_00945 3.72e-111 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MDOLOOFK_00946 1.61e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MDOLOOFK_00947 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
MDOLOOFK_00948 6.54e-307 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
MDOLOOFK_00951 1.57e-205 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MDOLOOFK_00952 1.43e-125 lemA - - S ko:K03744 - ko00000 LemA family
MDOLOOFK_00953 2.79e-116 ymdB - - S - - - Macro domain protein
MDOLOOFK_00954 5.36e-288 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MDOLOOFK_00955 3.24e-224 - - - - - - - -
MDOLOOFK_00956 2.2e-79 lysM - - M - - - LysM domain
MDOLOOFK_00957 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
MDOLOOFK_00958 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
MDOLOOFK_00959 6.67e-259 pbpX1 - - V - - - Beta-lactamase
MDOLOOFK_00960 1.51e-150 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
MDOLOOFK_00961 7.53e-163 gpm2 - - G - - - Phosphoglycerate mutase family
MDOLOOFK_00962 1.22e-229 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MDOLOOFK_00963 1.4e-09 - - - S - - - Protein of unknown function (DUF4044)
MDOLOOFK_00964 5.43e-122 mreD - - - ko:K03571 - ko00000,ko03036 -
MDOLOOFK_00965 8.62e-172 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MDOLOOFK_00966 2.53e-154 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
MDOLOOFK_00967 1.13e-84 - - - - - - - -
MDOLOOFK_00968 3.05e-63 - - - S - - - MazG-like family
MDOLOOFK_00969 4.26e-113 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
MDOLOOFK_00970 6.69e-171 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDOLOOFK_00971 4.43e-292 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MDOLOOFK_00972 6.79e-88 yxeH - - S - - - hydrolase
MDOLOOFK_00973 2.94e-200 - - - S - - - reductase
MDOLOOFK_00974 1.98e-278 yqjV - - EGP - - - Major Facilitator Superfamily
MDOLOOFK_00975 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MDOLOOFK_00976 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MDOLOOFK_00977 2.36e-94 - - - - - - - -
MDOLOOFK_00978 1.67e-83 - - - S - - - PD-(D/E)XK nuclease family transposase
MDOLOOFK_00979 4.53e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
MDOLOOFK_00980 4.44e-51 - - - - - - - -
MDOLOOFK_00981 0.0 - - - P ko:K06148 - ko00000,ko02000 ABC transporter
MDOLOOFK_00982 1.25e-76 - - - - - - - -
MDOLOOFK_00983 4.4e-132 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MDOLOOFK_00984 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
MDOLOOFK_00985 3.52e-311 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDOLOOFK_00986 5.8e-168 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDOLOOFK_00987 1.75e-134 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MDOLOOFK_00988 3.19e-165 - - - S - - - Alpha/beta hydrolase family
MDOLOOFK_00989 4.35e-198 epsV - - S - - - glycosyl transferase family 2
MDOLOOFK_00990 4.11e-08 - - - S - - - Domain of unknown function (DUF3841)
MDOLOOFK_00991 1.3e-115 - - - - - - - -
MDOLOOFK_00992 1.47e-77 - - - V - - - ABC transporter transmembrane region
MDOLOOFK_00993 8.51e-215 - - - V - - - ABC transporter transmembrane region
MDOLOOFK_00994 3.85e-17 - - - - - - - -
MDOLOOFK_00995 2.57e-147 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MDOLOOFK_00996 1.75e-201 degV1 - - S - - - DegV family
MDOLOOFK_00997 2.08e-170 - - - V - - - ABC transporter transmembrane region
MDOLOOFK_00998 1e-214 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
MDOLOOFK_00999 3.81e-18 - - - S - - - CsbD-like
MDOLOOFK_01000 1.2e-26 - - - S - - - Transglycosylase associated protein
MDOLOOFK_01001 0.0 - - - L - - - Transposase
MDOLOOFK_01002 1.73e-290 - - - I - - - Protein of unknown function (DUF2974)
MDOLOOFK_01003 8.25e-155 - - - S ko:K07507 - ko00000,ko02000 MgtC family
MDOLOOFK_01004 3.55e-192 - - - - - - - -
MDOLOOFK_01005 0.0 FbpA - - K - - - Fibronectin-binding protein
MDOLOOFK_01006 3.33e-32 - - - L - - - An automated process has identified a potential problem with this gene model
MDOLOOFK_01007 2.75e-76 - - - L - - - An automated process has identified a potential problem with this gene model
MDOLOOFK_01009 1.3e-115 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MDOLOOFK_01010 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDOLOOFK_01011 9.43e-175 - - - S ko:K12941 - ko00000,ko01002 Peptidase dimerisation domain
MDOLOOFK_01012 5.76e-55 - - - S ko:K12941 - ko00000,ko01002 Peptidase dimerisation domain
MDOLOOFK_01013 4.28e-309 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MDOLOOFK_01014 4.06e-287 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MDOLOOFK_01015 2.95e-213 - - - D - - - nuclear chromosome segregation
MDOLOOFK_01016 8.92e-136 - - - G - - - Phosphoglycerate mutase family
MDOLOOFK_01017 9.01e-115 - - - G - - - Histidine phosphatase superfamily (branch 1)
MDOLOOFK_01018 5.86e-148 - - - G - - - Antibiotic biosynthesis monooxygenase
MDOLOOFK_01019 6.02e-145 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MDOLOOFK_01021 0.0 oppA2 - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MDOLOOFK_01022 5.33e-233 - - - - - - - -
MDOLOOFK_01023 9.75e-163 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
MDOLOOFK_01024 3.68e-93 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
MDOLOOFK_01025 8.58e-220 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
MDOLOOFK_01026 8.73e-234 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDOLOOFK_01027 9.03e-46 noxC 1.5.1.39 - C ko:K19286 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 coenzyme F420-1:gamma-L-glutamate ligase activity
MDOLOOFK_01028 4.53e-88 - 3.1.3.102, 3.1.3.104 - G ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MDOLOOFK_01029 6.97e-200 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MDOLOOFK_01030 0.0 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
MDOLOOFK_01031 1.6e-11 - - - S - - - Putative threonine/serine exporter
MDOLOOFK_01032 7.36e-109 - - - S - - - Threonine/Serine exporter, ThrE
MDOLOOFK_01033 2.72e-144 - - - S - - - Peptidase_C39 like family
MDOLOOFK_01034 8.15e-284 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDOLOOFK_01035 1.73e-108 - - - - - - - -
MDOLOOFK_01036 1.59e-78 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
MDOLOOFK_01037 1.32e-74 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MDOLOOFK_01038 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MDOLOOFK_01040 1.19e-312 steT - - E ko:K03294 - ko00000 amino acid
MDOLOOFK_01041 9.3e-308 steT - - E ko:K03294 - ko00000 amino acid
MDOLOOFK_01042 6.41e-194 - - - - - - - -
MDOLOOFK_01043 7.09e-222 ydhF - - S - - - Aldo keto reductase
MDOLOOFK_01044 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
MDOLOOFK_01045 6.21e-266 pepA - - E - - - M42 glutamyl aminopeptidase
MDOLOOFK_01046 2.36e-102 - - - - - - - -
MDOLOOFK_01047 5.78e-92 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MDOLOOFK_01048 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MDOLOOFK_01049 4.54e-216 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MDOLOOFK_01050 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MDOLOOFK_01051 2.67e-119 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDOLOOFK_01052 1.69e-86 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MDOLOOFK_01053 4.36e-39 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDOLOOFK_01054 4.44e-161 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MDOLOOFK_01055 5.28e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MDOLOOFK_01056 1.86e-242 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MDOLOOFK_01057 1.51e-199 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MDOLOOFK_01058 6.6e-237 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MDOLOOFK_01059 7.02e-146 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MDOLOOFK_01060 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
MDOLOOFK_01063 9.67e-251 ampC - - V - - - Beta-lactamase
MDOLOOFK_01064 1.97e-275 - - - EGP - - - Major Facilitator
MDOLOOFK_01065 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MDOLOOFK_01067 1.09e-110 - - - - - - - -
MDOLOOFK_01068 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
MDOLOOFK_01069 6.59e-123 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MDOLOOFK_01070 8.12e-282 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
MDOLOOFK_01071 0.0 pepC4 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MDOLOOFK_01072 9.17e-16 - - - S - - - SLAP domain
MDOLOOFK_01073 2.54e-45 - - - E - - - amino acid
MDOLOOFK_01074 4.22e-123 yagE - - E - - - Amino acid permease
MDOLOOFK_01075 3.46e-216 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MDOLOOFK_01077 1.15e-314 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDOLOOFK_01078 5.96e-283 yfmL - - L - - - DEAD DEAH box helicase
MDOLOOFK_01079 7.44e-168 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MDOLOOFK_01080 9.05e-296 - - - E ko:K03294 - ko00000 amino acid
MDOLOOFK_01081 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MDOLOOFK_01082 4.8e-66 - - - L - - - PFAM transposase, IS4 family protein
MDOLOOFK_01083 4.26e-115 - - - L - - - PFAM transposase, IS4 family protein
MDOLOOFK_01085 3.07e-35 - - - S - - - Domain of unknown function (DUF771)
MDOLOOFK_01086 1.46e-37 - - - K - - - Helix-turn-helix domain
MDOLOOFK_01087 7.49e-198 - - - - - - - -
MDOLOOFK_01088 1.66e-44 - - - K - - - Transcriptional regulator
MDOLOOFK_01089 4.44e-225 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDOLOOFK_01090 1.39e-159 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MDOLOOFK_01091 6.1e-271 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MDOLOOFK_01092 2.01e-163 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MDOLOOFK_01093 1.28e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MDOLOOFK_01094 9.11e-198 - - - S - - - Aldo/keto reductase family
MDOLOOFK_01095 3.63e-221 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MDOLOOFK_01096 8.8e-262 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MDOLOOFK_01097 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter
MDOLOOFK_01098 9.41e-257 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
MDOLOOFK_01099 6.87e-256 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
MDOLOOFK_01100 8.75e-281 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MDOLOOFK_01101 1.66e-217 - - - - - - - -
MDOLOOFK_01102 9.86e-52 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MDOLOOFK_01103 3.51e-310 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MDOLOOFK_01104 8.39e-298 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
MDOLOOFK_01105 1.02e-82 yodB - - K - - - Transcriptional regulator, HxlR family
MDOLOOFK_01106 9.01e-179 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDOLOOFK_01107 1.23e-57 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
MDOLOOFK_01108 5.19e-90 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
MDOLOOFK_01109 8.72e-301 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MDOLOOFK_01110 9.39e-71 - - - - - - - -
MDOLOOFK_01111 2.42e-203 mutR - - K - - - Helix-turn-helix XRE-family like proteins
MDOLOOFK_01112 1.66e-101 - - - S - - - Putative adhesin
MDOLOOFK_01113 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
MDOLOOFK_01114 2.83e-263 napA - - P - - - Sodium/hydrogen exchanger family
MDOLOOFK_01115 0.0 cadA - - P - - - P-type ATPase
MDOLOOFK_01116 3.99e-106 ykuL - - S - - - (CBS) domain
MDOLOOFK_01117 1.5e-101 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
MDOLOOFK_01118 4.58e-136 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDOLOOFK_01119 6.66e-40 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
MDOLOOFK_01120 1.25e-13 - - - E - - - Amino acid permease
MDOLOOFK_01121 5.4e-190 - - - E - - - Amino acid permease
MDOLOOFK_01122 6.31e-68 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MDOLOOFK_01123 9.21e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MDOLOOFK_01124 1.18e-46 - - - S - - - Protein of unknown function (DUF2508)
MDOLOOFK_01125 5.43e-276 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MDOLOOFK_01126 2.5e-304 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MDOLOOFK_01127 2.66e-122 - - - S - - - SNARE associated Golgi protein
MDOLOOFK_01128 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
MDOLOOFK_01129 1.32e-219 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MDOLOOFK_01130 1.91e-195 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MDOLOOFK_01131 1.7e-147 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MDOLOOFK_01132 1.03e-144 - - - S - - - CYTH
MDOLOOFK_01133 8.16e-148 yjbH - - Q - - - Thioredoxin
MDOLOOFK_01134 3.2e-206 coiA - - S ko:K06198 - ko00000 Competence protein
MDOLOOFK_01135 6.12e-178 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MDOLOOFK_01137 2.22e-152 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MDOLOOFK_01138 3.93e-137 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MDOLOOFK_01141 3.85e-105 - - - S - - - AAA domain
MDOLOOFK_01142 9.99e-78 - - - S - - - F420-0:Gamma-glutamyl ligase
MDOLOOFK_01143 1.54e-264 XK27_01810 - - S - - - Calcineurin-like phosphoesterase
MDOLOOFK_01144 6.13e-110 - - - K - - - Acetyltransferase (GNAT) domain
MDOLOOFK_01145 2.69e-49 - - - - - - - -
MDOLOOFK_01146 2.92e-153 - - - G - - - Antibiotic biosynthesis monooxygenase
MDOLOOFK_01147 3.57e-95 - - - M - - - Rib/alpha-like repeat
MDOLOOFK_01148 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
MDOLOOFK_01149 1.2e-236 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
MDOLOOFK_01150 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MDOLOOFK_01151 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MDOLOOFK_01152 1.02e-164 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MDOLOOFK_01153 8.31e-228 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MDOLOOFK_01154 3.33e-109 - - - F - - - Phosphorylase superfamily
MDOLOOFK_01155 1.53e-126 qacA - - EGP - - - Major Facilitator
MDOLOOFK_01156 2.58e-64 - - - K - - - Bacterial regulatory proteins, tetR family
MDOLOOFK_01157 1.83e-258 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
MDOLOOFK_01158 4.71e-239 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MDOLOOFK_01159 1.6e-209 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
MDOLOOFK_01160 1.05e-244 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MDOLOOFK_01161 2.99e-20 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MDOLOOFK_01162 2.7e-218 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MDOLOOFK_01163 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MDOLOOFK_01164 6.79e-249 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MDOLOOFK_01165 7.9e-214 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MDOLOOFK_01166 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MDOLOOFK_01167 4.76e-308 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MDOLOOFK_01168 3.95e-82 - - - J ko:K07571 - ko00000 S1 RNA binding domain
MDOLOOFK_01170 9.54e-123 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDOLOOFK_01171 8.69e-186 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MDOLOOFK_01172 3.57e-47 - - - S - - - Lipopolysaccharide assembly protein A domain
MDOLOOFK_01173 1.74e-144 - - - - - - - -
MDOLOOFK_01174 2.79e-177 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MDOLOOFK_01175 6.38e-154 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MDOLOOFK_01176 3.14e-226 iunH 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
MDOLOOFK_01177 1.37e-126 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
MDOLOOFK_01178 8.23e-269 ylbM - - S - - - Belongs to the UPF0348 family
MDOLOOFK_01179 5.09e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MDOLOOFK_01180 6.49e-141 yqeK - - H - - - Hydrolase, HD family
MDOLOOFK_01181 4.34e-158 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MDOLOOFK_01182 1.44e-255 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
MDOLOOFK_01183 1.44e-110 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
MDOLOOFK_01184 3.19e-194 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MDOLOOFK_01185 8.69e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MDOLOOFK_01186 9.64e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MDOLOOFK_01187 2.63e-94 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MDOLOOFK_01188 1.46e-175 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
MDOLOOFK_01189 2.32e-16 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
MDOLOOFK_01190 5.45e-40 - - - - - - - -
MDOLOOFK_01191 1.23e-256 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
MDOLOOFK_01192 1.52e-40 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDOLOOFK_01193 1.81e-169 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MDOLOOFK_01194 1.7e-27 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MDOLOOFK_01195 9.17e-241 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
MDOLOOFK_01196 4.18e-109 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MDOLOOFK_01197 3.38e-28 - - - S - - - PD-(D/E)XK nuclease family transposase
MDOLOOFK_01198 2.33e-144 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MDOLOOFK_01199 8.71e-31 - - - G - - - Ribose/Galactose Isomerase
MDOLOOFK_01200 1.62e-71 - - - - - - - -
MDOLOOFK_01202 0.0 pepC2 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
MDOLOOFK_01203 1.07e-158 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MDOLOOFK_01204 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MDOLOOFK_01205 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MDOLOOFK_01207 1.05e-87 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
MDOLOOFK_01208 1.92e-148 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MDOLOOFK_01209 4.48e-230 ybcH - - D ko:K06889 - ko00000 Alpha beta
MDOLOOFK_01210 2.1e-106 - - - S - - - Conserved hypothetical protein 698
MDOLOOFK_01212 1.36e-69 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
MDOLOOFK_01213 3.17e-50 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
MDOLOOFK_01214 3.08e-209 - - - - - - - -
MDOLOOFK_01215 9.02e-78 cpdA - - S - - - Calcineurin-like phosphoesterase
MDOLOOFK_01216 9.67e-104 - - - - - - - -
MDOLOOFK_01217 1.43e-224 citR - - K - - - Putative sugar-binding domain
MDOLOOFK_01218 3.63e-309 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MDOLOOFK_01219 0.0 - - - S - - - Fibronectin type III domain
MDOLOOFK_01220 0.0 XK27_08315 - - M - - - Sulfatase
MDOLOOFK_01221 1.78e-146 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MDOLOOFK_01222 2.62e-229 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MDOLOOFK_01223 5.37e-106 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MDOLOOFK_01224 2.01e-174 - - - K - - - Helix-turn-helix XRE-family like proteins
MDOLOOFK_01225 9.44e-117 yokL3 - - J - - - Acetyltransferase (GNAT) domain
MDOLOOFK_01226 2.9e-192 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MDOLOOFK_01227 3.68e-14 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
MDOLOOFK_01228 5.56e-10 - - - T ko:K07172 - ko00000,ko02048 SpoVT / AbrB like domain
MDOLOOFK_01229 1.78e-114 - - - K ko:K03484 - ko00000,ko03000 Periplasmic binding protein domain
MDOLOOFK_01230 7.51e-145 - - - K - - - WHG domain
MDOLOOFK_01231 6.61e-221 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MDOLOOFK_01232 6.65e-183 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MDOLOOFK_01237 3.19e-105 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MDOLOOFK_01238 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MDOLOOFK_01239 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDOLOOFK_01240 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDOLOOFK_01241 7.71e-157 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
MDOLOOFK_01242 1.47e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MDOLOOFK_01243 1.39e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MDOLOOFK_01244 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MDOLOOFK_01245 6.63e-45 dltr - - K - - - response regulator
MDOLOOFK_01246 3.6e-146 - - - T - - - Region found in RelA / SpoT proteins
MDOLOOFK_01247 2.18e-34 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MDOLOOFK_01248 2.25e-201 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MDOLOOFK_01249 1.11e-13 - - - K - - - helix_turn_helix, arabinose operon control protein
MDOLOOFK_01250 4.33e-95 - - - - - - - -
MDOLOOFK_01251 5.86e-163 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MDOLOOFK_01252 1.59e-142 - - - K - - - Transcriptional regulator
MDOLOOFK_01253 6.82e-139 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MDOLOOFK_01254 1.83e-190 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDOLOOFK_01255 1.38e-162 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDOLOOFK_01256 1.67e-175 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MDOLOOFK_01257 2.58e-203 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
MDOLOOFK_01258 9.29e-111 usp5 - - T - - - universal stress protein
MDOLOOFK_01259 1.45e-190 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MDOLOOFK_01260 6.77e-116 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDOLOOFK_01261 4.83e-117 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
MDOLOOFK_01262 3.49e-28 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
MDOLOOFK_01264 7.86e-138 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
MDOLOOFK_01265 5.02e-179 - - - S - - - Uncharacterised protein, DegV family COG1307
MDOLOOFK_01266 1.66e-217 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MDOLOOFK_01267 3.95e-160 - - - S - - - SLAP domain
MDOLOOFK_01269 8.53e-45 - - - - - - - -
MDOLOOFK_01270 4.75e-101 - - - S - - - HIRAN
MDOLOOFK_01271 3.7e-164 - - - S - - - SLAP domain
MDOLOOFK_01272 5.99e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MDOLOOFK_01273 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MDOLOOFK_01274 3.77e-111 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MDOLOOFK_01275 3.95e-203 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MDOLOOFK_01276 1.34e-114 - - - G - - - Peptidase_C39 like family
MDOLOOFK_01277 1.52e-207 - - - M - - - NlpC/P60 family
MDOLOOFK_01278 1.68e-44 - - - G - - - Peptidase_C39 like family
MDOLOOFK_01279 8.64e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MDOLOOFK_01280 1.71e-181 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
MDOLOOFK_01281 1.85e-146 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MDOLOOFK_01282 1.85e-126 - - - L - - - An automated process has identified a potential problem with this gene model
MDOLOOFK_01283 8.1e-87 - - - S - - - Domain of unknown function DUF1828
MDOLOOFK_01284 7.91e-14 - - - - - - - -
MDOLOOFK_01285 8.84e-133 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
MDOLOOFK_01287 4.94e-181 - - - S - - - Sterol carrier protein domain
MDOLOOFK_01288 2.98e-195 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
MDOLOOFK_01289 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MDOLOOFK_01290 1.69e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MDOLOOFK_01291 7.31e-181 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
MDOLOOFK_01292 4.67e-116 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MDOLOOFK_01293 3.83e-311 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MDOLOOFK_01294 4.63e-131 - - - M - - - LysM domain protein
MDOLOOFK_01295 4.55e-75 - - - K - - - rpiR family
MDOLOOFK_01296 8.77e-187 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
MDOLOOFK_01297 1.35e-150 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDOLOOFK_01300 4.95e-98 - - - - - - - -
MDOLOOFK_01301 4.15e-172 - - - K ko:K03492 - ko00000,ko03000 UTRA
MDOLOOFK_01302 1.72e-107 - - - - - - - -
MDOLOOFK_01303 5.3e-85 - - - S ko:K07133 - ko00000 cog cog1373
MDOLOOFK_01304 4.85e-190 - - - - - - - -
MDOLOOFK_01305 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MDOLOOFK_01306 1.24e-181 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
MDOLOOFK_01307 1.83e-96 - - - - - - - -
MDOLOOFK_01308 1.74e-111 - - - - - - - -
MDOLOOFK_01309 2.79e-185 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
MDOLOOFK_01310 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDOLOOFK_01312 4.13e-83 - - - - - - - -
MDOLOOFK_01313 7.23e-127 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MDOLOOFK_01314 2.28e-123 - - - M - - - LysM domain protein
MDOLOOFK_01315 2.34e-130 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
MDOLOOFK_01316 6.13e-48 - - - - - - - -
MDOLOOFK_01317 5.16e-95 - - - K ko:K03484 - ko00000,ko03000 Periplasmic binding protein domain
MDOLOOFK_01318 7.33e-178 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MDOLOOFK_01319 9.73e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDOLOOFK_01320 1.62e-80 - - - S - - - response to antibiotic
MDOLOOFK_01321 5.37e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MDOLOOFK_01322 2.34e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MDOLOOFK_01323 6.73e-145 - - - G - - - Phosphoglycerate mutase family
MDOLOOFK_01324 5.35e-27 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MDOLOOFK_01325 1.89e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MDOLOOFK_01326 8.49e-146 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MDOLOOFK_01327 1.13e-41 - - - M - - - Lysin motif
MDOLOOFK_01328 1.13e-147 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MDOLOOFK_01329 1.4e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MDOLOOFK_01330 1.34e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MDOLOOFK_01331 8.21e-57 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MDOLOOFK_01332 1.74e-33 - - - K - - - Helix-turn-helix domain
MDOLOOFK_01335 7.8e-26 - - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MDOLOOFK_01336 9.28e-89 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDOLOOFK_01337 9.41e-134 - - - S - - - Fic/DOC family
MDOLOOFK_01338 5.9e-130 - - - S - - - ECF transporter, substrate-specific component
MDOLOOFK_01340 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MDOLOOFK_01341 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDOLOOFK_01342 4.04e-91 - - - S - - - DUF218 domain
MDOLOOFK_01343 9.89e-96 - - - S - - - DUF218 domain
MDOLOOFK_01345 6.5e-157 - - - K - - - Helix-turn-helix XRE-family like proteins
MDOLOOFK_01346 8.25e-156 - - - V - - - ABC transporter transmembrane region
MDOLOOFK_01347 5.3e-137 vanZ - - V - - - VanZ like family
MDOLOOFK_01348 2.09e-59 - - - - - - - -
MDOLOOFK_01349 2.59e-15 - - - S - - - PD-(D/E)XK nuclease family transposase
MDOLOOFK_01350 1.13e-46 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
MDOLOOFK_01351 3.54e-53 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
MDOLOOFK_01352 2.97e-110 - - - - - - - -
MDOLOOFK_01353 3e-42 lacE 2.7.1.207 - G ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system, EIIC
MDOLOOFK_01355 3.13e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MDOLOOFK_01356 1.89e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MDOLOOFK_01357 2.07e-73 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MDOLOOFK_01358 3.82e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MDOLOOFK_01359 3.62e-218 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDOLOOFK_01360 2.23e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MDOLOOFK_01361 8.4e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDOLOOFK_01362 5.5e-202 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDOLOOFK_01363 1.13e-177 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDOLOOFK_01364 8.77e-194 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MDOLOOFK_01365 3.22e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MDOLOOFK_01366 1.67e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MDOLOOFK_01367 6.49e-45 - - - - - - - -
MDOLOOFK_01368 1.68e-140 - - - C - - - nitroreductase
MDOLOOFK_01369 6.14e-160 ylmH - - S - - - S4 domain protein
MDOLOOFK_01370 8.59e-133 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MDOLOOFK_01371 6.56e-40 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
MDOLOOFK_01372 4.99e-93 - - - S - - - SLAP domain
MDOLOOFK_01373 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDOLOOFK_01374 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MDOLOOFK_01375 2.42e-215 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MDOLOOFK_01376 1.01e-180 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MDOLOOFK_01377 1.46e-28 - - - V - - - ABC transporter transmembrane region
MDOLOOFK_01378 2.1e-15 - - - - - - - -
MDOLOOFK_01379 1.98e-52 ybjQ - - S - - - Belongs to the UPF0145 family
MDOLOOFK_01380 4.02e-91 - - - T ko:K07171 - ko00000,ko01000,ko02048 Toxin-antitoxin system, toxin component, MazF family
MDOLOOFK_01381 1.32e-21 - - - - ko:K18829 - ko00000,ko02048 -
MDOLOOFK_01382 1.87e-58 - - - - - - - -
MDOLOOFK_01383 1.5e-103 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MDOLOOFK_01384 1.77e-139 - - - M - - - CHAP domain
MDOLOOFK_01385 2.26e-55 - - - M - - - family 8
MDOLOOFK_01386 2.83e-121 - - - S - - - VanZ like family
MDOLOOFK_01387 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MDOLOOFK_01388 1.31e-215 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MDOLOOFK_01389 0.0 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
MDOLOOFK_01390 1.29e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MDOLOOFK_01391 2.16e-136 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MDOLOOFK_01392 1.92e-199 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MDOLOOFK_01393 8.75e-78 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MDOLOOFK_01394 2.19e-87 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MDOLOOFK_01395 3.92e-113 lysR5 - - K - - - LysR substrate binding domain
MDOLOOFK_01396 1.47e-151 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
MDOLOOFK_01399 9.5e-132 - - - S - - - EDD domain protein, DegV family
MDOLOOFK_01400 2.53e-106 - - - K - - - Transcriptional regulator, MarR family
MDOLOOFK_01401 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MDOLOOFK_01402 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
MDOLOOFK_01403 1.79e-131 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MDOLOOFK_01404 0.0 - - - G - - - MFS/sugar transport protein
MDOLOOFK_01405 2.68e-119 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
MDOLOOFK_01406 6.64e-127 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
MDOLOOFK_01407 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MDOLOOFK_01408 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MDOLOOFK_01409 6.25e-268 camS - - S - - - sex pheromone
MDOLOOFK_01410 5.42e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDOLOOFK_01411 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MDOLOOFK_01412 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDOLOOFK_01413 9.65e-220 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
MDOLOOFK_01414 2.61e-148 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
MDOLOOFK_01415 1.7e-74 - - - - - - - -
MDOLOOFK_01416 4.03e-186 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
MDOLOOFK_01417 2.79e-309 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MDOLOOFK_01418 2.72e-118 - - - M - - - Glycosyl transferase family 2
MDOLOOFK_01419 1.05e-68 - - - - - - - -
MDOLOOFK_01420 3.25e-141 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MDOLOOFK_01422 7.64e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MDOLOOFK_01423 1.49e-233 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MDOLOOFK_01424 2.12e-132 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDOLOOFK_01425 1.23e-126 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MDOLOOFK_01426 4.3e-197 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MDOLOOFK_01427 9.67e-199 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
MDOLOOFK_01428 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MDOLOOFK_01435 1.73e-84 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MDOLOOFK_01436 1.33e-57 - - - C - - - Aldo keto reductase
MDOLOOFK_01437 7.55e-53 - - - S - - - Transglycosylase associated protein
MDOLOOFK_01438 3.1e-108 ynbB - - P - - - aluminum resistance
MDOLOOFK_01439 2.06e-88 - - - - - - - -
MDOLOOFK_01440 2.99e-45 - - - K - - - LytTr DNA-binding domain
MDOLOOFK_01441 1.05e-119 - - - S - - - membrane
MDOLOOFK_01442 2.61e-23 - - - - - - - -
MDOLOOFK_01443 1.59e-254 - - - S - - - Putative peptidoglycan binding domain
MDOLOOFK_01444 6.46e-202 - - - C - - - Domain of unknown function (DUF4931)
MDOLOOFK_01445 5.5e-155 - - - - - - - -
MDOLOOFK_01446 7.18e-184 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
MDOLOOFK_01447 2.92e-182 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
MDOLOOFK_01448 1.66e-144 - - - G - - - phosphoglycerate mutase
MDOLOOFK_01449 2.68e-67 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
MDOLOOFK_01450 1.18e-64 - - - D ko:K03496 - ko00000,ko03036,ko04812 VirC1 protein
MDOLOOFK_01451 4.92e-06 - - - S - - - SLAP domain
MDOLOOFK_01452 1.54e-56 - - - S - - - Enterocin A Immunity
MDOLOOFK_01454 1.35e-71 ytpP - - CO - - - Thioredoxin
MDOLOOFK_01455 8.78e-157 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDOLOOFK_01456 3.68e-313 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MDOLOOFK_01457 5.98e-302 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
MDOLOOFK_01458 1.13e-223 - - - S - - - SLAP domain
MDOLOOFK_01459 0.0 - - - M - - - Peptidase family M1 domain
MDOLOOFK_01460 1.57e-82 - - - I - - - Alpha/beta hydrolase family
MDOLOOFK_01461 1.2e-102 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MDOLOOFK_01462 3.22e-56 yoeB - - S ko:K19158 - ko00000,ko01000,ko02048 YoeB-like toxin of bacterial type II toxin-antitoxin system
MDOLOOFK_01463 2.45e-58 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
MDOLOOFK_01464 1.12e-20 - - - - - - - -
MDOLOOFK_01465 0.000358 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
MDOLOOFK_01466 7.25e-76 - - - S - - - SLAP domain
MDOLOOFK_01467 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MDOLOOFK_01468 3.98e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MDOLOOFK_01470 3.58e-193 - - - I - - - Acyl-transferase
MDOLOOFK_01471 6.19e-202 arbx - - M - - - Glycosyl transferase family 8
MDOLOOFK_01472 4.7e-237 - - - M - - - Glycosyl transferase family 8
MDOLOOFK_01473 4.5e-234 - - - M - - - Glycosyl transferase family 8
MDOLOOFK_01474 3.18e-62 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
MDOLOOFK_01475 4.04e-94 - - - S - - - Domain of unknown function (DUF3284)
MDOLOOFK_01476 4e-24 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MDOLOOFK_01477 1.06e-72 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MDOLOOFK_01478 1.23e-68 - - - - - - - -
MDOLOOFK_01479 7.56e-111 - 3.4.21.96 - S ko:K01361 - ko00000,ko01000,ko01002,ko03110 SLAP domain
MDOLOOFK_01480 1.31e-245 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MDOLOOFK_01481 4.59e-124 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
MDOLOOFK_01482 2.13e-170 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
MDOLOOFK_01483 3.7e-112 - - - S - - - ECF transporter, substrate-specific component
MDOLOOFK_01484 2.12e-167 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
MDOLOOFK_01485 8.75e-200 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MDOLOOFK_01486 1.4e-80 yabA - - L - - - Involved in initiation control of chromosome replication
MDOLOOFK_01487 1.98e-197 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MDOLOOFK_01488 1.58e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
MDOLOOFK_01489 1.15e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MDOLOOFK_01491 1.74e-106 potE - - E - - - Amino Acid
MDOLOOFK_01492 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MDOLOOFK_01493 5.46e-233 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MDOLOOFK_01494 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MDOLOOFK_01495 4.41e-216 yitL - - S ko:K00243 - ko00000 S1 domain
MDOLOOFK_01496 1.73e-215 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
MDOLOOFK_01497 7.27e-42 - - - - - - - -
MDOLOOFK_01498 6.29e-82 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
MDOLOOFK_01499 3.73e-23 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MDOLOOFK_01500 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MDOLOOFK_01501 5.68e-156 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MDOLOOFK_01502 5.32e-213 - - - K - - - LysR substrate binding domain
MDOLOOFK_01503 3.35e-117 - - - S - - - PD-(D/E)XK nuclease family transposase
MDOLOOFK_01504 2.84e-73 codA - - F - - - Cytidine and deoxycytidylate deaminase zinc-binding region
MDOLOOFK_01506 3.59e-54 comX - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
MDOLOOFK_01507 1.19e-45 - - - - - - - -
MDOLOOFK_01508 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MDOLOOFK_01509 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MDOLOOFK_01510 3.73e-33 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MDOLOOFK_01511 3.01e-131 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MDOLOOFK_01512 3.82e-90 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MDOLOOFK_01513 1.05e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MDOLOOFK_01516 4.58e-87 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDOLOOFK_01519 5.88e-163 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MDOLOOFK_01520 4.25e-56 - - - - - - - -
MDOLOOFK_01521 1.27e-134 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MDOLOOFK_01522 2.32e-43 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
MDOLOOFK_01523 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MDOLOOFK_01524 4.63e-104 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
MDOLOOFK_01526 0.000768 - - - S - - - Domain of Unknown Function with PDB structure (DUF3850)
MDOLOOFK_01529 8.3e-68 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MDOLOOFK_01530 5.08e-211 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MDOLOOFK_01531 2.75e-304 - - - L - - - Transposase DDE domain
MDOLOOFK_01532 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MDOLOOFK_01533 1.06e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MDOLOOFK_01534 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MDOLOOFK_01535 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MDOLOOFK_01536 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MDOLOOFK_01537 6.73e-133 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MDOLOOFK_01538 4.87e-238 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MDOLOOFK_01539 7.58e-69 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MDOLOOFK_01540 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MDOLOOFK_01541 3.02e-275 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MDOLOOFK_01543 9.78e-64 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas2CT1978)
MDOLOOFK_01544 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
MDOLOOFK_01545 1.33e-225 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
MDOLOOFK_01546 1.78e-204 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MDOLOOFK_01547 2.34e-242 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MDOLOOFK_01548 2.34e-122 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MDOLOOFK_01552 6.41e-225 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MDOLOOFK_01553 0.0 yclK - - T - - - Histidine kinase
MDOLOOFK_01554 6.88e-171 - - - K - - - Transcriptional regulatory protein, C terminal
MDOLOOFK_01555 1.11e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MDOLOOFK_01556 3.32e-286 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MDOLOOFK_01557 2.74e-83 - - - M - - - Protein of unknown function (DUF3737)
MDOLOOFK_01558 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MDOLOOFK_01559 1.16e-265 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MDOLOOFK_01560 5.43e-195 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MDOLOOFK_01561 3.67e-316 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MDOLOOFK_01562 3.74e-302 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MDOLOOFK_01564 5.12e-211 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDOLOOFK_01565 7.78e-280 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MDOLOOFK_01566 3.14e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
MDOLOOFK_01567 2.18e-215 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MDOLOOFK_01568 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
MDOLOOFK_01569 8.09e-28 - - - - - - - -
MDOLOOFK_01572 1.15e-179 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
MDOLOOFK_01573 5.54e-292 - - - E - - - amino acid
MDOLOOFK_01574 7.58e-244 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
MDOLOOFK_01575 1.84e-263 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
MDOLOOFK_01578 4.04e-240 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDOLOOFK_01579 3.73e-23 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MDOLOOFK_01580 3.46e-56 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
MDOLOOFK_01581 2.09e-63 yoeB - - S ko:K19158 - ko00000,ko01000,ko02048 YoeB-like toxin of bacterial type II toxin-antitoxin system
MDOLOOFK_01582 6.98e-242 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MDOLOOFK_01583 4.24e-191 epsB - - M - - - biosynthesis protein
MDOLOOFK_01584 4.13e-162 ywqD - - D - - - Capsular exopolysaccharide family
MDOLOOFK_01585 2.22e-184 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
MDOLOOFK_01586 1.7e-157 epsE2 - - M - - - Bacterial sugar transferase
MDOLOOFK_01587 8.54e-175 cps4F - - M - - - Glycosyl transferases group 1
MDOLOOFK_01589 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MDOLOOFK_01590 4.22e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MDOLOOFK_01591 5.85e-313 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MDOLOOFK_01592 4.35e-143 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MDOLOOFK_01597 4.04e-42 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MDOLOOFK_01598 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MDOLOOFK_01599 1.8e-99 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MDOLOOFK_01600 4.28e-312 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MDOLOOFK_01601 5.29e-141 - - - S - - - SLAP domain
MDOLOOFK_01602 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MDOLOOFK_01603 3.87e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MDOLOOFK_01604 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MDOLOOFK_01605 5.56e-217 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
MDOLOOFK_01606 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MDOLOOFK_01607 7.92e-135 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MDOLOOFK_01608 3.04e-296 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
MDOLOOFK_01609 3.06e-198 msmR - - K - - - AraC-like ligand binding domain
MDOLOOFK_01610 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MDOLOOFK_01611 1.69e-61 - - - F - - - AAA domain
MDOLOOFK_01612 5.49e-103 - - - K - - - acetyltransferase
MDOLOOFK_01613 1.55e-311 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDOLOOFK_01614 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MDOLOOFK_01615 1.67e-78 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MDOLOOFK_01616 3.76e-89 - - - S - - - Domain of unknown function (DUF1934)
MDOLOOFK_01617 3.83e-163 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MDOLOOFK_01618 1.79e-216 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDOLOOFK_01619 6e-208 - - - C - - - Domain of unknown function (DUF4931)
MDOLOOFK_01620 6.21e-242 srrA1 - - G ko:K02027,ko:K17244 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MDOLOOFK_01621 1.85e-47 srrA1 - - G ko:K02027,ko:K17244 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MDOLOOFK_01624 1.31e-20 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MDOLOOFK_01625 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MDOLOOFK_01626 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MDOLOOFK_01627 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MDOLOOFK_01628 1.18e-66 yrzB - - S - - - Belongs to the UPF0473 family
MDOLOOFK_01629 9.37e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MDOLOOFK_01630 5.32e-57 yrzL - - S - - - Belongs to the UPF0297 family
MDOLOOFK_01631 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MDOLOOFK_01632 5.36e-305 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MDOLOOFK_01633 7.32e-46 yabO - - J - - - S4 domain protein
MDOLOOFK_01634 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MDOLOOFK_01635 1.89e-134 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MDOLOOFK_01636 2.93e-234 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MDOLOOFK_01637 1.69e-33 - - - S ko:K07090 - ko00000 membrane transporter protein
MDOLOOFK_01638 6.37e-160 - - - G - - - Belongs to the phosphoglycerate mutase family
MDOLOOFK_01639 5.08e-207 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
MDOLOOFK_01640 2.42e-33 - - - - - - - -
MDOLOOFK_01641 3.43e-164 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDOLOOFK_01642 1.99e-235 - - - S - - - AAA domain
MDOLOOFK_01643 8.69e-66 - - - - - - - -
MDOLOOFK_01644 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MDOLOOFK_01645 9.62e-230 - - - E ko:K03307 - ko00000 Sodium:solute symporter family
MDOLOOFK_01646 1.82e-194 - 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
MDOLOOFK_01647 1.3e-95 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional
MDOLOOFK_01648 1.45e-81 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MDOLOOFK_01649 2.87e-107 - - - S - - - An automated process has identified a potential problem with this gene model
MDOLOOFK_01650 3.54e-126 - - - S - - - Protein of unknown function (DUF3100)
MDOLOOFK_01651 2.92e-146 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MDOLOOFK_01652 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MDOLOOFK_01653 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MDOLOOFK_01654 9e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MDOLOOFK_01655 3.08e-241 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
MDOLOOFK_01656 3.69e-30 - - - - - - - -
MDOLOOFK_01657 1.94e-100 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
MDOLOOFK_01658 1.68e-55 - - - - - - - -
MDOLOOFK_01659 8.52e-93 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
MDOLOOFK_01660 7.88e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
MDOLOOFK_01661 2.05e-217 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
MDOLOOFK_01662 1.68e-229 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
MDOLOOFK_01663 5.65e-171 yebC - - K - - - Transcriptional regulatory protein
MDOLOOFK_01664 3.98e-160 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MDOLOOFK_01665 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MDOLOOFK_01666 6.66e-226 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MDOLOOFK_01667 1.57e-50 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MDOLOOFK_01668 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MDOLOOFK_01669 1.26e-225 ydbI - - K - - - AI-2E family transporter
MDOLOOFK_01670 1.67e-135 - - - E - - - GDSL-like Lipase/Acylhydrolase
MDOLOOFK_01671 1.26e-26 - - - - - - - -
MDOLOOFK_01672 1.59e-315 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
MDOLOOFK_01673 3.02e-176 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDOLOOFK_01674 1.17e-168 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MDOLOOFK_01675 2.47e-225 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MDOLOOFK_01676 2.41e-173 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MDOLOOFK_01677 6.83e-183 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MDOLOOFK_01678 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
MDOLOOFK_01679 6.54e-222 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDOLOOFK_01680 5e-252 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDOLOOFK_01681 6.71e-241 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDOLOOFK_01682 1.34e-191 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDOLOOFK_01683 5.39e-291 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MDOLOOFK_01684 6.51e-226 - - - S - - - Cysteine-rich secretory protein family
MDOLOOFK_01686 7.42e-55 - - - - - - - -
MDOLOOFK_01687 1.73e-167 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
MDOLOOFK_01688 7.03e-76 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
MDOLOOFK_01689 5.48e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MDOLOOFK_01690 1.19e-212 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MDOLOOFK_01691 1.82e-198 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
MDOLOOFK_01692 5.24e-187 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDOLOOFK_01693 3.28e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDOLOOFK_01694 5e-152 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
MDOLOOFK_01695 6.03e-307 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MDOLOOFK_01696 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MDOLOOFK_01697 5e-57 - - - K - - - Helix-turn-helix XRE-family like proteins
MDOLOOFK_01698 1.8e-83 - - - S - - - Phage derived protein Gp49-like (DUF891)
MDOLOOFK_01699 1.56e-18 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MDOLOOFK_01700 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MDOLOOFK_01701 6.36e-230 yvdE - - K - - - helix_turn _helix lactose operon repressor
MDOLOOFK_01702 7.48e-188 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MDOLOOFK_01703 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MDOLOOFK_01704 3.05e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MDOLOOFK_01705 4.84e-24 - - - - - - - -
MDOLOOFK_01706 1.58e-101 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MDOLOOFK_01707 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MDOLOOFK_01708 1.3e-40 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MDOLOOFK_01709 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MDOLOOFK_01710 1.23e-186 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MDOLOOFK_01711 9.94e-71 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
MDOLOOFK_01712 3.52e-124 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
MDOLOOFK_01713 1.74e-107 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MDOLOOFK_01714 3.48e-245 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MDOLOOFK_01715 2.58e-124 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
MDOLOOFK_01716 2.56e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MDOLOOFK_01717 1.07e-108 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MDOLOOFK_01718 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MDOLOOFK_01719 4.83e-277 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MDOLOOFK_01720 7.42e-174 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
MDOLOOFK_01721 2.13e-194 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MDOLOOFK_01722 2.76e-221 ybbR - - S - - - YbbR-like protein
MDOLOOFK_01723 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MDOLOOFK_01724 8.04e-190 - - - S - - - hydrolase
MDOLOOFK_01725 1.87e-97 copY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
MDOLOOFK_01726 5.74e-153 - - - - - - - -
MDOLOOFK_01727 3.07e-112 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDOLOOFK_01728 1.85e-264 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MDOLOOFK_01729 8.39e-195 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MDOLOOFK_01730 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDOLOOFK_01731 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)