ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
KGMEOLOC_00001 4.46e-42 csfB - - S - - - Inhibitor of sigma-G Gin
KGMEOLOC_00002 1.24e-137 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
KGMEOLOC_00003 4.58e-249 yaaN - - P - - - Belongs to the TelA family
KGMEOLOC_00004 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
KGMEOLOC_00005 1.9e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KGMEOLOC_00006 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
KGMEOLOC_00007 1.04e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
KGMEOLOC_00008 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KGMEOLOC_00009 9e-189 yaaT - - S - - - stage 0 sporulation protein
KGMEOLOC_00010 3.08e-56 yabA - - L - - - Involved in initiation control of chromosome replication
KGMEOLOC_00011 3.99e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
KGMEOLOC_00012 6.96e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
KGMEOLOC_00013 4.93e-211 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KGMEOLOC_00014 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
KGMEOLOC_00015 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KGMEOLOC_00016 2.22e-186 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
KGMEOLOC_00017 2.49e-310 yabE - - T - - - protein conserved in bacteria
KGMEOLOC_00018 7.62e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KGMEOLOC_00019 2.07e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KGMEOLOC_00020 1.41e-209 yabG - - S ko:K06436 - ko00000 peptidase
KGMEOLOC_00021 5.32e-53 veg - - S - - - protein conserved in bacteria
KGMEOLOC_00022 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
KGMEOLOC_00023 2.73e-206 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KGMEOLOC_00024 5.67e-197 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
KGMEOLOC_00025 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
KGMEOLOC_00026 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
KGMEOLOC_00027 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KGMEOLOC_00028 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KGMEOLOC_00029 3.72e-138 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KGMEOLOC_00030 6.07e-137 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KGMEOLOC_00031 1.1e-54 yabK - - S - - - Peptide ABC transporter permease
KGMEOLOC_00032 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KGMEOLOC_00033 8.02e-119 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
KGMEOLOC_00034 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KGMEOLOC_00035 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
KGMEOLOC_00036 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KGMEOLOC_00037 5.47e-66 yabP - - S - - - Sporulation protein YabP
KGMEOLOC_00038 1.18e-134 yabQ - - S - - - spore cortex biosynthesis protein
KGMEOLOC_00039 1.2e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
KGMEOLOC_00040 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
KGMEOLOC_00043 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
KGMEOLOC_00044 3.79e-166 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
KGMEOLOC_00045 1.4e-237 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
KGMEOLOC_00046 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KGMEOLOC_00047 1.05e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
KGMEOLOC_00048 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KGMEOLOC_00049 1.15e-187 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KGMEOLOC_00050 3.19e-206 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KGMEOLOC_00051 3.86e-205 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
KGMEOLOC_00052 4.4e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KGMEOLOC_00053 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KGMEOLOC_00054 1.31e-139 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
KGMEOLOC_00055 1.53e-210 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
KGMEOLOC_00056 2.24e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KGMEOLOC_00057 1.13e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KGMEOLOC_00058 8.2e-118 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KGMEOLOC_00059 6.1e-40 yazB - - K - - - transcriptional
KGMEOLOC_00060 5.32e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KGMEOLOC_00061 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
KGMEOLOC_00062 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
KGMEOLOC_00063 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
KGMEOLOC_00064 1.14e-83 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
KGMEOLOC_00065 1.63e-258 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
KGMEOLOC_00066 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
KGMEOLOC_00067 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KGMEOLOC_00068 7.66e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KGMEOLOC_00069 8.6e-251 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
KGMEOLOC_00070 3.02e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KGMEOLOC_00071 3.02e-111 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KGMEOLOC_00072 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KGMEOLOC_00073 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
KGMEOLOC_00074 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KGMEOLOC_00075 4.11e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KGMEOLOC_00076 2.48e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KGMEOLOC_00077 4.03e-115 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
KGMEOLOC_00078 1.39e-150 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
KGMEOLOC_00079 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KGMEOLOC_00080 1.28e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
KGMEOLOC_00081 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KGMEOLOC_00082 8.66e-161 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KGMEOLOC_00083 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KGMEOLOC_00084 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KGMEOLOC_00085 4.37e-141 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
KGMEOLOC_00086 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KGMEOLOC_00087 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KGMEOLOC_00088 5.94e-46 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
KGMEOLOC_00089 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KGMEOLOC_00090 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KGMEOLOC_00091 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KGMEOLOC_00092 2.35e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KGMEOLOC_00093 1.78e-243 ybaC - - S - - - Alpha/beta hydrolase family
KGMEOLOC_00094 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
KGMEOLOC_00095 1.77e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KGMEOLOC_00096 3.68e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
KGMEOLOC_00097 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KGMEOLOC_00098 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KGMEOLOC_00099 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KGMEOLOC_00100 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KGMEOLOC_00101 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KGMEOLOC_00102 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KGMEOLOC_00103 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
KGMEOLOC_00104 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KGMEOLOC_00105 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KGMEOLOC_00106 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KGMEOLOC_00107 5.43e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KGMEOLOC_00108 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KGMEOLOC_00109 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KGMEOLOC_00110 3.14e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KGMEOLOC_00111 8.29e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KGMEOLOC_00112 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KGMEOLOC_00113 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
KGMEOLOC_00114 5.15e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
KGMEOLOC_00115 1.34e-296 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KGMEOLOC_00116 9.14e-156 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KGMEOLOC_00117 1.4e-183 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
KGMEOLOC_00118 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KGMEOLOC_00119 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
KGMEOLOC_00120 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KGMEOLOC_00121 2.28e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KGMEOLOC_00122 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KGMEOLOC_00123 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
KGMEOLOC_00124 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KGMEOLOC_00125 1.26e-192 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KGMEOLOC_00126 1.37e-178 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KGMEOLOC_00127 9.1e-184 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KGMEOLOC_00128 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KGMEOLOC_00129 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
KGMEOLOC_00130 7.48e-187 ybaJ - - Q - - - Methyltransferase domain
KGMEOLOC_00131 8.36e-113 yizA - - S - - - Damage-inducible protein DinB
KGMEOLOC_00132 3.22e-103 ybaK - - S - - - Protein of unknown function (DUF2521)
KGMEOLOC_00133 1.98e-173 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
KGMEOLOC_00134 2.21e-254 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KGMEOLOC_00135 6.81e-103 gerD - - - ko:K06294 - ko00000 -
KGMEOLOC_00136 1.25e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
KGMEOLOC_00137 6.38e-183 pdaB - - G - - - Polysaccharide deacetylase
KGMEOLOC_00138 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
KGMEOLOC_00139 5.49e-282 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
KGMEOLOC_00140 1.27e-313 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KGMEOLOC_00141 8.07e-233 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
KGMEOLOC_00142 1.69e-257 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
KGMEOLOC_00143 1e-290 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
KGMEOLOC_00144 1.87e-223 ybaS - - S - - - Na -dependent transporter
KGMEOLOC_00145 4.6e-151 ybbA - - S ko:K07017 - ko00000 Putative esterase
KGMEOLOC_00146 7.1e-230 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KGMEOLOC_00147 2.19e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KGMEOLOC_00148 2.1e-220 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
KGMEOLOC_00149 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
KGMEOLOC_00150 3.46e-304 ybbC - - S - - - protein conserved in bacteria
KGMEOLOC_00151 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
KGMEOLOC_00152 2.62e-52 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
KGMEOLOC_00153 1.95e-316 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
KGMEOLOC_00154 1.83e-313 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KGMEOLOC_00155 1.2e-210 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KGMEOLOC_00156 3.15e-113 ybbJ - - J - - - acetyltransferase
KGMEOLOC_00157 1.93e-101 ybbK - - S - - - Protein of unknown function (DUF523)
KGMEOLOC_00163 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KGMEOLOC_00164 1.11e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
KGMEOLOC_00165 9e-188 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KGMEOLOC_00166 1.64e-303 ybbR - - S - - - protein conserved in bacteria
KGMEOLOC_00167 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KGMEOLOC_00168 2.45e-115 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KGMEOLOC_00169 3.94e-286 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KGMEOLOC_00170 1.64e-203 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KGMEOLOC_00171 1.27e-141 - - - S - - - ABC-2 family transporter protein
KGMEOLOC_00172 7.92e-35 ybdN - - - - - - -
KGMEOLOC_00174 2.14e-163 - - - T ko:K11630 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGMEOLOC_00175 3.07e-240 - - - T ko:K19168 - ko00000,ko02048 Histidine kinase
KGMEOLOC_00176 3.96e-177 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KGMEOLOC_00177 0.0 - - - V ko:K02004,ko:K11632 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
KGMEOLOC_00178 4.5e-15 - - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KGMEOLOC_00179 3.09e-208 dkgB - - S - - - Aldo/keto reductase family
KGMEOLOC_00180 7.37e-136 yxaC - - M - - - effector of murein hydrolase
KGMEOLOC_00181 1.41e-67 - - - S ko:K06518 - ko00000,ko02000 LrgA family
KGMEOLOC_00182 3.52e-96 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KGMEOLOC_00183 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KGMEOLOC_00184 7.56e-119 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KGMEOLOC_00185 1.99e-261 - - - T - - - COG4585 Signal transduction histidine kinase
KGMEOLOC_00186 5.23e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
KGMEOLOC_00187 3.5e-220 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
KGMEOLOC_00188 1.8e-269 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
KGMEOLOC_00189 7.79e-261 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KGMEOLOC_00190 2.34e-35 - - - - - - - -
KGMEOLOC_00191 2.68e-105 - - - S - - - Domain of unknown function (DUF4879)
KGMEOLOC_00192 1.75e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
KGMEOLOC_00193 1.42e-150 yqeB - - - - - - -
KGMEOLOC_00194 7.84e-55 ybyB - - - - - - -
KGMEOLOC_00195 0.0 ybeC - - E - - - amino acid
KGMEOLOC_00198 5.14e-22 - - - S - - - Protein of unknown function (DUF2651)
KGMEOLOC_00199 1.04e-213 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
KGMEOLOC_00200 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
KGMEOLOC_00201 5.8e-23 - - - S - - - Protein of unknown function (DUF2651)
KGMEOLOC_00202 2.02e-267 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
KGMEOLOC_00204 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
KGMEOLOC_00205 2.44e-45 - - - - - - - -
KGMEOLOC_00206 1.69e-107 - - - K - - - Helix-turn-helix XRE-family like proteins
KGMEOLOC_00207 4.68e-259 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
KGMEOLOC_00208 9.69e-273 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KGMEOLOC_00209 1.56e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KGMEOLOC_00210 4.26e-113 ybfM - - S - - - SNARE associated Golgi protein
KGMEOLOC_00211 7.49e-195 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
KGMEOLOC_00212 1.09e-57 ybfN - - - - - - -
KGMEOLOC_00213 3.47e-246 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
KGMEOLOC_00214 8.22e-272 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KGMEOLOC_00215 5.02e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
KGMEOLOC_00216 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KGMEOLOC_00217 6.39e-234 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
KGMEOLOC_00218 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
KGMEOLOC_00219 1.11e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
KGMEOLOC_00220 1.6e-281 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KGMEOLOC_00221 1e-221 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
KGMEOLOC_00222 5.89e-36 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
KGMEOLOC_00223 2.42e-49 - - - L - - - Transposase
KGMEOLOC_00224 4.47e-200 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KGMEOLOC_00225 8.46e-146 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
KGMEOLOC_00226 7.8e-238 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
KGMEOLOC_00227 1.14e-83 ydfP - - S ko:K15977 - ko00000 DoxX
KGMEOLOC_00228 3.92e-76 ydfQ - - CO - - - Thioredoxin
KGMEOLOC_00229 1.63e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
KGMEOLOC_00230 1.33e-104 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
KGMEOLOC_00231 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
KGMEOLOC_00232 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KGMEOLOC_00233 8.93e-163 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KGMEOLOC_00234 1.25e-156 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KGMEOLOC_00235 7.62e-270 ycbU - - E - - - Selenocysteine lyase
KGMEOLOC_00236 2.61e-315 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
KGMEOLOC_00237 1.54e-130 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
KGMEOLOC_00238 1.24e-257 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KGMEOLOC_00239 9.81e-149 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
KGMEOLOC_00240 2.04e-253 yccF - - K ko:K07039 - ko00000 SEC-C motif
KGMEOLOC_00241 4.79e-222 yccK - - C - - - Aldo keto reductase
KGMEOLOC_00242 3.39e-228 ycdA - - S - - - Domain of unknown function (DUF5105)
KGMEOLOC_00243 2.1e-46 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KGMEOLOC_00244 3.51e-287 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KGMEOLOC_00245 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KGMEOLOC_00246 6.25e-122 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
KGMEOLOC_00247 2.45e-249 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
KGMEOLOC_00248 9.39e-183 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
KGMEOLOC_00249 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
KGMEOLOC_00250 4.44e-215 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KGMEOLOC_00251 6.92e-171 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KGMEOLOC_00252 1.19e-174 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KGMEOLOC_00253 1.2e-237 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KGMEOLOC_00254 2.86e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
KGMEOLOC_00255 3.63e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
KGMEOLOC_00256 2.46e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
KGMEOLOC_00257 2.12e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
KGMEOLOC_00258 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
KGMEOLOC_00259 1.17e-246 yceH - - P - - - Belongs to the TelA family
KGMEOLOC_00260 1.1e-277 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
KGMEOLOC_00261 7.71e-294 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
KGMEOLOC_00262 2.45e-185 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
KGMEOLOC_00263 7e-211 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
KGMEOLOC_00264 5.82e-273 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
KGMEOLOC_00265 8.03e-294 ycgA - - S - - - Membrane
KGMEOLOC_00266 1.32e-107 ycgB - - - - - - -
KGMEOLOC_00267 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
KGMEOLOC_00268 1.39e-229 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KGMEOLOC_00269 0.0 mdr - - EGP - - - the major facilitator superfamily
KGMEOLOC_00270 6.92e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
KGMEOLOC_00271 1.11e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
KGMEOLOC_00272 4.54e-196 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
KGMEOLOC_00273 1.43e-72 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KGMEOLOC_00274 1.99e-229 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KGMEOLOC_00275 3.22e-146 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
KGMEOLOC_00276 5.46e-193 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KGMEOLOC_00277 2.77e-06 - - - S - - - Bacillus cereus group antimicrobial protein
KGMEOLOC_00278 4.05e-142 tmrB - - S - - - AAA domain
KGMEOLOC_00279 7.21e-193 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
KGMEOLOC_00280 1.66e-304 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KGMEOLOC_00281 8.64e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KGMEOLOC_00282 2.41e-235 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
KGMEOLOC_00283 2.23e-191 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
KGMEOLOC_00284 9.61e-217 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
KGMEOLOC_00285 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
KGMEOLOC_00286 3.14e-311 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KGMEOLOC_00287 1.43e-290 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
KGMEOLOC_00288 8.53e-245 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
KGMEOLOC_00289 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
KGMEOLOC_00290 5.95e-75 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
KGMEOLOC_00291 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KGMEOLOC_00292 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KGMEOLOC_00293 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
KGMEOLOC_00294 2.09e-287 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
KGMEOLOC_00295 4.25e-291 yciC - - S - - - GTPases (G3E family)
KGMEOLOC_00296 7.79e-285 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KGMEOLOC_00297 9.31e-97 yckC - - S - - - membrane
KGMEOLOC_00298 3.31e-68 - - - S - - - Protein of unknown function (DUF2680)
KGMEOLOC_00299 0.0 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KGMEOLOC_00300 5.81e-92 nin - - S - - - Competence protein J (ComJ)
KGMEOLOC_00301 1.88e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
KGMEOLOC_00302 2.67e-125 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
KGMEOLOC_00303 3.82e-140 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
KGMEOLOC_00304 1.01e-84 hxlR - - K - - - transcriptional
KGMEOLOC_00305 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGMEOLOC_00306 6.5e-274 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGMEOLOC_00307 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGMEOLOC_00308 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
KGMEOLOC_00309 3.05e-180 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
KGMEOLOC_00310 0.0 - - - E - - - Aminotransferase class I and II
KGMEOLOC_00311 2.38e-86 - - - S - - - YcxB-like protein
KGMEOLOC_00313 8.2e-219 ycxC - - EG - - - EamA-like transporter family
KGMEOLOC_00314 0.0 ycxD - - K - - - GntR family transcriptional regulator
KGMEOLOC_00315 1.11e-168 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
KGMEOLOC_00316 3.11e-144 yczE - - S ko:K07149 - ko00000 membrane
KGMEOLOC_00317 8.3e-171 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KGMEOLOC_00318 3.03e-154 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
KGMEOLOC_00319 2.8e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
KGMEOLOC_00320 5.96e-206 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
KGMEOLOC_00321 1.46e-131 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
KGMEOLOC_00322 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
KGMEOLOC_00323 2.83e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
KGMEOLOC_00324 3.51e-102 yclD - - - - - - -
KGMEOLOC_00325 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
KGMEOLOC_00326 0.0 yclG - - M - - - Pectate lyase superfamily protein
KGMEOLOC_00328 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
KGMEOLOC_00329 1.3e-305 gerKC - - S ko:K06297 - ko00000 spore germination
KGMEOLOC_00330 7.92e-250 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
KGMEOLOC_00331 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KGMEOLOC_00332 4.43e-120 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KGMEOLOC_00333 1.56e-183 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KGMEOLOC_00334 1.49e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
KGMEOLOC_00335 1.38e-170 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KGMEOLOC_00336 6.14e-280 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
KGMEOLOC_00337 0.0 yxeQ - - S - - - MmgE/PrpD family
KGMEOLOC_00338 4.84e-160 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KGMEOLOC_00339 0.0 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
KGMEOLOC_00340 9.08e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGMEOLOC_00341 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
KGMEOLOC_00342 1.09e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
KGMEOLOC_00345 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KGMEOLOC_00346 1.91e-211 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KGMEOLOC_00347 3.45e-213 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KGMEOLOC_00348 5.63e-176 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KGMEOLOC_00349 1.18e-224 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
KGMEOLOC_00350 0.0 ycnB - - EGP - - - the major facilitator superfamily
KGMEOLOC_00351 3.14e-197 ycnC - - K - - - Transcriptional regulator
KGMEOLOC_00352 4.14e-176 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
KGMEOLOC_00353 3.39e-60 ycnE - - S - - - Monooxygenase
KGMEOLOC_00354 1.37e-70 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KGMEOLOC_00355 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KGMEOLOC_00356 2.65e-288 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KGMEOLOC_00357 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KGMEOLOC_00358 8.27e-191 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
KGMEOLOC_00359 2.4e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGMEOLOC_00360 2.05e-131 ycnI - - S - - - protein conserved in bacteria
KGMEOLOC_00361 2.95e-253 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
KGMEOLOC_00362 4.09e-52 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
KGMEOLOC_00363 1.49e-138 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
KGMEOLOC_00364 9.6e-73 - - - - - - - -
KGMEOLOC_00365 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
KGMEOLOC_00366 4.11e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
KGMEOLOC_00367 4.59e-270 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
KGMEOLOC_00368 1.74e-88 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
KGMEOLOC_00370 4.66e-178 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
KGMEOLOC_00371 6.12e-181 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
KGMEOLOC_00372 3.24e-272 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
KGMEOLOC_00373 2.15e-195 ycsI - - S - - - Belongs to the D-glutamate cyclase family
KGMEOLOC_00374 4.86e-177 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
KGMEOLOC_00375 7.58e-244 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
KGMEOLOC_00376 2.93e-170 kipR - - K - - - Transcriptional regulator
KGMEOLOC_00377 5.71e-152 ycsK - - E - - - anatomical structure formation involved in morphogenesis
KGMEOLOC_00379 5.95e-75 yczJ - - S - - - biosynthesis
KGMEOLOC_00380 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
KGMEOLOC_00381 7.67e-223 ycsN - - S - - - Oxidoreductase
KGMEOLOC_00382 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
KGMEOLOC_00383 0.0 ydaB - - IQ - - - acyl-CoA ligase
KGMEOLOC_00384 9.37e-208 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGMEOLOC_00385 1.17e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
KGMEOLOC_00386 1.07e-153 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KGMEOLOC_00387 1.83e-101 ydaG - - S - - - general stress protein
KGMEOLOC_00388 1.87e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
KGMEOLOC_00389 5.59e-64 ydzA - - EGP - - - Domain of unknown function (DUF3817)
KGMEOLOC_00390 7.97e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
KGMEOLOC_00391 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KGMEOLOC_00392 4.53e-264 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
KGMEOLOC_00393 9.5e-168 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
KGMEOLOC_00394 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
KGMEOLOC_00395 1.12e-303 ydaM - - M - - - Glycosyl transferase family group 2
KGMEOLOC_00396 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
KGMEOLOC_00397 0.0 ydaO - - E - - - amino acid
KGMEOLOC_00398 3.34e-101 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
KGMEOLOC_00399 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
KGMEOLOC_00400 1.45e-98 - - - K - - - acetyltransferase
KGMEOLOC_00402 2.54e-19 - - - - - - - -
KGMEOLOC_00403 5.37e-271 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
KGMEOLOC_00405 5.42e-12 - - - - - - - -
KGMEOLOC_00407 7.56e-116 - - - - - - - -
KGMEOLOC_00408 1.79e-131 - - - - - - - -
KGMEOLOC_00409 1.29e-54 - - - - - - - -
KGMEOLOC_00410 1.6e-289 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
KGMEOLOC_00412 1.95e-45 ydaT - - - - - - -
KGMEOLOC_00413 6.73e-97 yvaD - - S - - - Family of unknown function (DUF5360)
KGMEOLOC_00414 7.05e-72 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
KGMEOLOC_00415 2.29e-183 ydbA - - P - - - EcsC protein family
KGMEOLOC_00416 2.34e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
KGMEOLOC_00417 4.02e-61 ydbB - - G - - - Cupin domain
KGMEOLOC_00418 4.45e-83 ydbC - - S - - - Domain of unknown function (DUF4937
KGMEOLOC_00419 1.64e-199 ydbD - - P ko:K07217 - ko00000 Catalase
KGMEOLOC_00420 4.65e-256 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
KGMEOLOC_00421 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
KGMEOLOC_00422 3.67e-153 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
KGMEOLOC_00423 3.91e-287 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KGMEOLOC_00424 8.61e-231 ydbI - - S - - - AI-2E family transporter
KGMEOLOC_00425 1.67e-221 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KGMEOLOC_00426 2.44e-167 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KGMEOLOC_00427 2.29e-70 ydbL - - - - - - -
KGMEOLOC_00428 3.47e-267 ydbM - - I - - - acyl-CoA dehydrogenase
KGMEOLOC_00429 1.13e-15 - - - S - - - Fur-regulated basic protein B
KGMEOLOC_00430 2.8e-79 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KGMEOLOC_00431 8.5e-116 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KGMEOLOC_00432 2.25e-74 ydbP - - CO - - - Thioredoxin
KGMEOLOC_00433 5.31e-259 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
KGMEOLOC_00434 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KGMEOLOC_00435 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KGMEOLOC_00436 6.83e-109 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
KGMEOLOC_00437 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
KGMEOLOC_00438 2.08e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
KGMEOLOC_00439 5.81e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KGMEOLOC_00440 1.57e-235 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
KGMEOLOC_00441 7.21e-282 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KGMEOLOC_00442 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
KGMEOLOC_00443 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
KGMEOLOC_00444 1.05e-186 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
KGMEOLOC_00445 1.09e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
KGMEOLOC_00446 1.73e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
KGMEOLOC_00447 2.17e-242 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
KGMEOLOC_00448 9.77e-71 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
KGMEOLOC_00449 7.1e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
KGMEOLOC_00450 1.14e-180 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KGMEOLOC_00451 4.22e-143 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
KGMEOLOC_00452 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
KGMEOLOC_00453 1.78e-21 - - - - - - - -
KGMEOLOC_00454 1.81e-77 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
KGMEOLOC_00462 3.44e-127 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
KGMEOLOC_00463 4.71e-98 - - - S - - - SnoaL-like polyketide cyclase
KGMEOLOC_00464 5.42e-182 yddR - - S - - - Zn-dependent hydrolases of the beta-lactamase fold
KGMEOLOC_00465 1.16e-93 lrpA - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
KGMEOLOC_00466 2.73e-201 - - - S - - - Serine aminopeptidase, S33
KGMEOLOC_00467 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
KGMEOLOC_00468 5.16e-66 ohrR - - K - - - Transcriptional regulator
KGMEOLOC_00469 8.64e-112 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
KGMEOLOC_00470 4.48e-98 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
KGMEOLOC_00471 1.59e-85 - - - S - - - YjbR
KGMEOLOC_00472 3.48e-98 ywnA - - K - - - Transcriptional regulator
KGMEOLOC_00473 1.4e-147 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
KGMEOLOC_00474 7.04e-133 - - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
KGMEOLOC_00475 2.48e-173 - - - C ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
KGMEOLOC_00476 2.13e-233 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KGMEOLOC_00477 1.62e-227 - - - C - - - COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KGMEOLOC_00478 6.06e-75 - - - K - - - Transcriptional regulator
KGMEOLOC_00479 1.13e-252 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
KGMEOLOC_00480 3.87e-42 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
KGMEOLOC_00481 2.51e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
KGMEOLOC_00482 2.63e-53 yrkD - - S - - - protein conserved in bacteria
KGMEOLOC_00483 2.38e-109 yrkE - - O - - - DsrE/DsrF/DrsH-like family
KGMEOLOC_00484 1.17e-84 - - - P - - - Rhodanese Homology Domain
KGMEOLOC_00485 3.94e-133 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
KGMEOLOC_00486 4.1e-254 yrkH - - P - - - Rhodanese Homology Domain
KGMEOLOC_00487 3.2e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
KGMEOLOC_00488 2.16e-167 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
KGMEOLOC_00489 9.82e-164 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
KGMEOLOC_00490 1.18e-139 - - - S - - - Protein of unknown function (DUF2812)
KGMEOLOC_00491 9.96e-69 - - - K - - - Transcriptional regulator PadR-like family
KGMEOLOC_00492 2.32e-199 ybfA - - K - - - FR47-like protein
KGMEOLOC_00493 4.93e-303 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
KGMEOLOC_00494 1.84e-236 - - - S - - - Patatin-like phospholipase
KGMEOLOC_00495 4.3e-111 - - - S - - - DinB superfamily
KGMEOLOC_00496 1.48e-86 - - - G - - - Cupin domain
KGMEOLOC_00499 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
KGMEOLOC_00500 5.28e-104 - - - E ko:K07032 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KGMEOLOC_00501 1.17e-219 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
KGMEOLOC_00502 2.69e-257 trkA - - P ko:K07222 - ko00000 Oxidoreductase
KGMEOLOC_00504 4.01e-132 yrkC - - G - - - Cupin domain
KGMEOLOC_00506 2.2e-116 ykkA - - S - - - Protein of unknown function (DUF664)
KGMEOLOC_00507 6.3e-192 dapA7 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
KGMEOLOC_00509 6.11e-256 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
KGMEOLOC_00510 2.23e-75 ydeH - - - - - - -
KGMEOLOC_00511 4.51e-111 - - - F - - - nucleoside 2-deoxyribosyltransferase
KGMEOLOC_00512 3.94e-250 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KGMEOLOC_00513 9.13e-191 - - - Q - - - ubiE/COQ5 methyltransferase family
KGMEOLOC_00514 5.46e-193 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7 - H ko:K00941,ko:K14153 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KGMEOLOC_00515 1.69e-298 - - - G - - - Haloacid dehalogenase-like hydrolase
KGMEOLOC_00516 8.2e-219 - - - S - - - Sodium Bile acid symporter family
KGMEOLOC_00517 6.64e-260 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
KGMEOLOC_00518 7.29e-87 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
KGMEOLOC_00519 3.29e-113 nhaC_1 - - C - - - antiporter
KGMEOLOC_00520 3.08e-162 nhaC_1 - - C - - - antiporter
KGMEOLOC_00521 0.0 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
KGMEOLOC_00522 4.37e-148 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
KGMEOLOC_00524 3.41e-31 - - - I - - - Ribosomal RNA adenine dimethylase
KGMEOLOC_00525 2.59e-104 - - - I - - - Ribosomal RNA adenine dimethylase
KGMEOLOC_00526 1.06e-159 - - - T - - - Transcriptional regulator
KGMEOLOC_00527 9.62e-248 - - - T - - - COG0642 Signal transduction histidine kinase
KGMEOLOC_00528 7.73e-139 - - - S - - - SNARE associated Golgi protein
KGMEOLOC_00529 1.36e-253 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
KGMEOLOC_00530 1.2e-132 ydeS - - K - - - Transcriptional regulator
KGMEOLOC_00531 3.17e-203 ydeK - - EG - - - -transporter
KGMEOLOC_00532 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KGMEOLOC_00533 1.25e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
KGMEOLOC_00534 3.54e-35 yraE - - - ko:K06440 - ko00000 -
KGMEOLOC_00535 1.29e-283 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KGMEOLOC_00536 2.86e-85 yraF - - M - - - Spore coat protein
KGMEOLOC_00537 2.95e-50 yraG - - - ko:K06440 - ko00000 -
KGMEOLOC_00538 1.96e-281 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KGMEOLOC_00539 1.19e-143 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KGMEOLOC_00540 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
KGMEOLOC_00541 1.04e-174 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
KGMEOLOC_00542 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
KGMEOLOC_00543 5.71e-131 ynaD - - J - - - Acetyltransferase (GNAT) domain
KGMEOLOC_00544 6.07e-192 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KGMEOLOC_00545 7.09e-251 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
KGMEOLOC_00546 8.22e-270 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
KGMEOLOC_00547 8.62e-292 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KGMEOLOC_00548 2.73e-201 - - - K - - - Helix-turn-helix XRE-family like proteins
KGMEOLOC_00549 9e-158 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
KGMEOLOC_00550 2.62e-109 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
KGMEOLOC_00551 1.29e-196 bltR - - K - - - helix_turn_helix, mercury resistance
KGMEOLOC_00552 1.61e-194 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KGMEOLOC_00553 2.44e-149 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
KGMEOLOC_00554 6.92e-190 - - - Q - - - ubiE/COQ5 methyltransferase family
KGMEOLOC_00555 3.44e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
KGMEOLOC_00556 2e-26 - 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
KGMEOLOC_00557 2.79e-155 ydhC - - K - - - FCD
KGMEOLOC_00558 4.77e-291 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KGMEOLOC_00561 0.0 pbpE - - V - - - Beta-lactamase
KGMEOLOC_00563 4.3e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
KGMEOLOC_00564 1.11e-247 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
KGMEOLOC_00565 7.17e-172 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
KGMEOLOC_00566 3.96e-155 - - - K ko:K05799 - ko00000,ko03000 FCD
KGMEOLOC_00567 1.23e-276 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
KGMEOLOC_00568 1.48e-65 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
KGMEOLOC_00569 4.48e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
KGMEOLOC_00570 3.63e-136 yvdT_1 - - K - - - Transcriptional regulator
KGMEOLOC_00571 0.0 ybeC - - E - - - amino acid
KGMEOLOC_00572 4.41e-214 ydhU - - P ko:K07217 - ko00000 Catalase
KGMEOLOC_00573 5.06e-113 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
KGMEOLOC_00574 2.83e-237 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
KGMEOLOC_00575 0.0 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KGMEOLOC_00578 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
KGMEOLOC_00583 2.25e-239 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KGMEOLOC_00584 9.02e-113 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
KGMEOLOC_00585 1.02e-162 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
KGMEOLOC_00586 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KGMEOLOC_00587 3.92e-246 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KGMEOLOC_00588 2.77e-232 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
KGMEOLOC_00589 5.12e-159 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
KGMEOLOC_00590 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KGMEOLOC_00591 1.29e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KGMEOLOC_00592 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KGMEOLOC_00593 8.18e-163 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KGMEOLOC_00594 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
KGMEOLOC_00595 4.09e-165 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
KGMEOLOC_00596 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KGMEOLOC_00597 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KGMEOLOC_00598 0.0 ykuG - - M - - - Putative peptidoglycan binding domain
KGMEOLOC_00601 8.34e-86 - - - - - - - -
KGMEOLOC_00602 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
KGMEOLOC_00603 1.51e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
KGMEOLOC_00604 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
KGMEOLOC_00605 2.29e-225 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
KGMEOLOC_00606 5.98e-40 yjdJ - - S - - - Domain of unknown function (DUF4306)
KGMEOLOC_00607 7.04e-149 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
KGMEOLOC_00608 1.55e-229 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KGMEOLOC_00609 8.16e-165 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
KGMEOLOC_00610 1.94e-224 ydjI - - S - - - virion core protein (lumpy skin disease virus)
KGMEOLOC_00611 0.0 oatA - - I - - - Acyltransferase family
KGMEOLOC_00612 1.68e-194 rsiV - - S - - - Protein of unknown function (DUF3298)
KGMEOLOC_00613 1.87e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KGMEOLOC_00614 1.74e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
KGMEOLOC_00615 3.92e-83 ydjM - - M - - - Lytic transglycolase
KGMEOLOC_00616 2.12e-196 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
KGMEOLOC_00618 2.02e-47 ydjO - - S - - - Cold-inducible protein YdjO
KGMEOLOC_00619 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
KGMEOLOC_00620 1.68e-304 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
KGMEOLOC_00621 3.04e-199 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KGMEOLOC_00622 2.39e-227 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
KGMEOLOC_00623 6.89e-278 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
KGMEOLOC_00624 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
KGMEOLOC_00625 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
KGMEOLOC_00626 2.81e-123 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KGMEOLOC_00627 0.0 - - - S - - - Domain of unknown function (DUF4179)
KGMEOLOC_00628 1.23e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
KGMEOLOC_00629 1.42e-173 yebC - - M - - - Membrane
KGMEOLOC_00631 2.66e-120 yebE - - S - - - UPF0316 protein
KGMEOLOC_00632 6.56e-40 yebG - - S - - - NETI protein
KGMEOLOC_00633 1.13e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KGMEOLOC_00634 3.9e-288 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KGMEOLOC_00635 6.38e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KGMEOLOC_00636 2.13e-169 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
KGMEOLOC_00637 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KGMEOLOC_00638 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KGMEOLOC_00639 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KGMEOLOC_00640 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KGMEOLOC_00641 4.57e-245 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
KGMEOLOC_00642 7.3e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KGMEOLOC_00643 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
KGMEOLOC_00644 1.85e-303 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
KGMEOLOC_00645 4.18e-34 - - - S - - - Protein of unknown function (DUF2892)
KGMEOLOC_00646 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
KGMEOLOC_00647 7.32e-248 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
KGMEOLOC_00648 2.03e-67 yerC - - S - - - protein conserved in bacteria
KGMEOLOC_00649 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
KGMEOLOC_00650 1.51e-164 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KGMEOLOC_00651 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
KGMEOLOC_00652 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KGMEOLOC_00653 2.74e-286 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
KGMEOLOC_00654 5.83e-254 yerI - - S - - - homoserine kinase type II (protein kinase fold)
KGMEOLOC_00655 5.01e-159 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
KGMEOLOC_00656 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KGMEOLOC_00657 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KGMEOLOC_00658 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KGMEOLOC_00659 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KGMEOLOC_00660 1.63e-199 yerO - - K - - - Transcriptional regulator
KGMEOLOC_00661 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KGMEOLOC_00662 5.16e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KGMEOLOC_00663 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KGMEOLOC_00664 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
KGMEOLOC_00665 4.67e-299 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
KGMEOLOC_00666 5.55e-173 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
KGMEOLOC_00667 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
KGMEOLOC_00671 2.72e-23 - - - V ko:K07451 - ko00000,ko01000,ko02048 Domain of unknown function (DUF3578)
KGMEOLOC_00672 6.25e-248 - - - V ko:K07451 - ko00000,ko01000,ko02048 Domain of unknown function (DUF3578)
KGMEOLOC_00673 1.42e-118 - - - S - - - Protein of unknown function, DUF600
KGMEOLOC_00674 2.84e-108 - - - S - - - Protein of unknown function, DUF600
KGMEOLOC_00675 1.06e-110 - - - S - - - Protein of unknown function, DUF600
KGMEOLOC_00676 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
KGMEOLOC_00677 3.12e-162 yeeN - - K - - - transcriptional regulatory protein
KGMEOLOC_00679 4.61e-61 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
KGMEOLOC_00680 1.62e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
KGMEOLOC_00681 1.48e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
KGMEOLOC_00682 3.17e-129 yesJ - - K - - - Acetyltransferase (GNAT) family
KGMEOLOC_00683 5.92e-05 - - - - - - - -
KGMEOLOC_00684 8.99e-157 yetF - - S - - - membrane
KGMEOLOC_00685 5.49e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
KGMEOLOC_00686 2.27e-86 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KGMEOLOC_00687 7.98e-200 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KGMEOLOC_00688 1.34e-31 - - - S - - - Uncharacterized small protein (DUF2292)
KGMEOLOC_00689 1.82e-73 - - - H - - - riboflavin kinase activity
KGMEOLOC_00690 1.54e-136 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
KGMEOLOC_00691 2.08e-117 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
KGMEOLOC_00692 2.19e-267 yetM - - CH - - - FAD binding domain
KGMEOLOC_00693 2.38e-252 yetN - - S - - - Protein of unknown function (DUF3900)
KGMEOLOC_00694 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
KGMEOLOC_00696 5.83e-67 - - - K - - - Winged helix DNA-binding domain
KGMEOLOC_00697 7.9e-214 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KGMEOLOC_00698 1.31e-162 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
KGMEOLOC_00699 4.77e-130 - - - S - - - protein homooligomerization
KGMEOLOC_00700 1.98e-167 - - - - - - - -
KGMEOLOC_00701 7.91e-247 - - - S - - - ATP diphosphatase activity
KGMEOLOC_00702 0.0 - - - S ko:K09136 - ko00000,ko03009 YcaO cyclodehydratase, ATP-ad Mg2+-binding
KGMEOLOC_00703 5.49e-196 - - - C - - - Nitroreductase family
KGMEOLOC_00704 3.67e-150 - - - S - - - CAAX protease self-immunity
KGMEOLOC_00705 7.44e-190 - 2.1.1.163, 2.1.1.201 - Q ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 methyltransferase
KGMEOLOC_00707 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
KGMEOLOC_00708 6.17e-190 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
KGMEOLOC_00709 6.8e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
KGMEOLOC_00710 6.89e-232 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
KGMEOLOC_00711 5.31e-287 yfnE - - S - - - Glycosyltransferase like family 2
KGMEOLOC_00712 1.46e-240 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
KGMEOLOC_00713 2.7e-278 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KGMEOLOC_00714 4.33e-315 yfnA - - E ko:K03294 - ko00000 amino acid
KGMEOLOC_00715 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KGMEOLOC_00716 2.85e-169 yfmS - - NT - - - chemotaxis protein
KGMEOLOC_00717 2.1e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KGMEOLOC_00718 9.2e-270 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
KGMEOLOC_00719 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KGMEOLOC_00720 3.03e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
KGMEOLOC_00721 1.25e-264 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
KGMEOLOC_00722 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KGMEOLOC_00723 3.91e-268 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
KGMEOLOC_00724 3.25e-26 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
KGMEOLOC_00725 1.19e-43 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
KGMEOLOC_00726 2.54e-243 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
KGMEOLOC_00727 4.44e-31 - - - S - - - Protein of unknown function (DUF3212)
KGMEOLOC_00728 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
KGMEOLOC_00729 8.27e-311 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
KGMEOLOC_00730 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
KGMEOLOC_00731 7.54e-41 - - - Q - - - PFAM Collagen triple helix
KGMEOLOC_00732 6.04e-95 - - - Q - - - PFAM Collagen triple helix
KGMEOLOC_00733 2.96e-188 - - - Q - - - calcium- and calmodulin-responsive adenylate cyclase activity
KGMEOLOC_00734 2.34e-121 M1-820 - - Q - - - Collagen triple helix repeat (20 copies)
KGMEOLOC_00735 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
KGMEOLOC_00736 8.33e-156 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
KGMEOLOC_00737 8.33e-228 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
KGMEOLOC_00738 2.01e-287 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
KGMEOLOC_00739 5.08e-194 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KGMEOLOC_00740 1.49e-279 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KGMEOLOC_00741 3.36e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
KGMEOLOC_00742 5.28e-160 yflK - - S - - - protein conserved in bacteria
KGMEOLOC_00743 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
KGMEOLOC_00744 1.98e-26 yflI - - - - - - -
KGMEOLOC_00745 1.67e-66 yflH - - S - - - Protein of unknown function (DUF3243)
KGMEOLOC_00746 6.62e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
KGMEOLOC_00747 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
KGMEOLOC_00748 7.03e-98 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
KGMEOLOC_00749 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
KGMEOLOC_00750 8.46e-84 ydhN1 - - S - - - Domain of unknown function (DUF1992)
KGMEOLOC_00751 8.64e-106 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KGMEOLOC_00752 8.17e-52 ydgA - - S - - - Spore germination protein gerPA/gerPF
KGMEOLOC_00753 1.85e-53 ydgB - - S - - - Spore germination protein gerPA/gerPF
KGMEOLOC_00754 3.27e-315 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KGMEOLOC_00755 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
KGMEOLOC_00756 2.89e-166 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
KGMEOLOC_00757 1.45e-158 frp - - C - - - nitroreductase
KGMEOLOC_00758 6e-167 yibF - - S - - - YibE/F-like protein
KGMEOLOC_00759 8.4e-260 yibE - - S - - - YibE/F-like protein
KGMEOLOC_00761 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
KGMEOLOC_00762 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
KGMEOLOC_00763 1.58e-239 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KGMEOLOC_00764 6.12e-210 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KGMEOLOC_00765 1.82e-177 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KGMEOLOC_00766 8.51e-253 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KGMEOLOC_00767 2.53e-42 yfkK - - S - - - Belongs to the UPF0435 family
KGMEOLOC_00768 1.69e-112 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KGMEOLOC_00769 1.29e-70 yfkI - - S - - - gas vesicle protein
KGMEOLOC_00770 1.37e-185 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
KGMEOLOC_00771 6.71e-12 - - - - - - - -
KGMEOLOC_00772 2.61e-281 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KGMEOLOC_00773 8.42e-239 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
KGMEOLOC_00774 5.66e-186 yfkD - - S - - - YfkD-like protein
KGMEOLOC_00775 5.2e-189 yfkC - - M - - - Mechanosensitive ion channel
KGMEOLOC_00776 2.06e-282 yfkA - - S - - - YfkB-like domain
KGMEOLOC_00777 7.99e-37 yfjT - - - - - - -
KGMEOLOC_00778 1.07e-199 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
KGMEOLOC_00779 2.05e-195 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
KGMEOLOC_00781 2.24e-236 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
KGMEOLOC_00782 7.59e-212 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KGMEOLOC_00783 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KGMEOLOC_00784 2.97e-245 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KGMEOLOC_00785 1.42e-122 yfjM - - S - - - Psort location Cytoplasmic, score
KGMEOLOC_00786 5.55e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KGMEOLOC_00787 9.2e-243 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KGMEOLOC_00788 6.13e-278 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KGMEOLOC_00789 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KGMEOLOC_00790 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
KGMEOLOC_00791 6.64e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
KGMEOLOC_00792 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KGMEOLOC_00793 2.69e-179 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
KGMEOLOC_00794 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KGMEOLOC_00795 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
KGMEOLOC_00796 3.39e-229 yobO - - M - - - COG5434 Endopolygalacturonase
KGMEOLOC_00797 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
KGMEOLOC_00798 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KGMEOLOC_00799 1.36e-82 yfiD3 - - S - - - DoxX
KGMEOLOC_00800 3.46e-207 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
KGMEOLOC_00801 2.03e-221 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KGMEOLOC_00802 5.62e-126 padR - - K - - - transcriptional
KGMEOLOC_00803 1.26e-144 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
KGMEOLOC_00804 7.2e-241 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KGMEOLOC_00805 0.0 - 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
KGMEOLOC_00806 2.87e-61 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
KGMEOLOC_00807 1.24e-132 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
KGMEOLOC_00808 0.0 yfiU - - EGP - - - the major facilitator superfamily
KGMEOLOC_00809 1.38e-108 yfiV - - K - - - transcriptional
KGMEOLOC_00810 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KGMEOLOC_00811 3.35e-214 yfhB - - S - - - PhzF family
KGMEOLOC_00812 8.22e-138 yfhC - - C - - - nitroreductase
KGMEOLOC_00813 3.61e-34 yfhD - - S - - - YfhD-like protein
KGMEOLOC_00815 1.08e-217 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
KGMEOLOC_00816 2.81e-80 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
KGMEOLOC_00817 1.41e-46 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
KGMEOLOC_00818 1.12e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
KGMEOLOC_00819 1.42e-268 yfhI - - EGP - - - -transporter
KGMEOLOC_00821 2.1e-217 mpr - - M - - - Belongs to the peptidase S1B family
KGMEOLOC_00822 3.12e-60 yfhJ - - S - - - WVELL protein
KGMEOLOC_00823 2.94e-124 yfhK - - T - - - Bacterial SH3 domain homologues
KGMEOLOC_00824 6.28e-59 yfhL - - S - - - SdpI/YhfL protein family
KGMEOLOC_00825 5.82e-220 - - - S - - - Alpha/beta hydrolase family
KGMEOLOC_00826 1.35e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
KGMEOLOC_00827 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
KGMEOLOC_00828 2.52e-237 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
KGMEOLOC_00829 4.48e-262 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
KGMEOLOC_00830 2.54e-50 yfhS - - - - - - -
KGMEOLOC_00831 3.81e-173 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGMEOLOC_00832 4.77e-06 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
KGMEOLOC_00833 1.4e-49 ygaB - - S - - - YgaB-like protein
KGMEOLOC_00834 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
KGMEOLOC_00835 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
KGMEOLOC_00836 1.58e-240 ygaE - - S - - - Membrane
KGMEOLOC_00837 6.86e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
KGMEOLOC_00838 3.41e-112 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
KGMEOLOC_00839 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
KGMEOLOC_00840 4.67e-75 ygzB - - S - - - UPF0295 protein
KGMEOLOC_00841 2.75e-213 ygxA - - S - - - Nucleotidyltransferase-like
KGMEOLOC_00842 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
KGMEOLOC_00861 0.0 - - - C - - - Na+/H+ antiporter family
KGMEOLOC_00862 2.07e-173 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
KGMEOLOC_00863 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KGMEOLOC_00864 0.0 ygaK - - C - - - Berberine and berberine like
KGMEOLOC_00867 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
KGMEOLOC_00868 2.52e-238 - - - S ko:K07045 - ko00000 Amidohydrolase
KGMEOLOC_00869 1.1e-180 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KGMEOLOC_00870 4.48e-232 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
KGMEOLOC_00871 3.01e-188 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
KGMEOLOC_00872 7.7e-276 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
KGMEOLOC_00873 1.18e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KGMEOLOC_00874 3.16e-107 ygaO - - - - - - -
KGMEOLOC_00875 9.41e-32 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
KGMEOLOC_00877 1.64e-148 yhzB - - S - - - B3/4 domain
KGMEOLOC_00878 2.08e-287 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KGMEOLOC_00879 2.13e-226 yhbB - - S - - - Putative amidase domain
KGMEOLOC_00880 8.36e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KGMEOLOC_00881 3.4e-141 yhbD - - K - - - Protein of unknown function (DUF4004)
KGMEOLOC_00882 1.49e-87 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
KGMEOLOC_00883 2.47e-95 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
KGMEOLOC_00884 1.23e-07 - - - - - - - -
KGMEOLOC_00885 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
KGMEOLOC_00886 4.34e-281 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
KGMEOLOC_00887 4.15e-98 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
KGMEOLOC_00888 1.54e-132 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
KGMEOLOC_00889 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
KGMEOLOC_00890 9.09e-129 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
KGMEOLOC_00891 1.41e-72 yhcC - - - - - - -
KGMEOLOC_00892 2.33e-66 - - - - - - - -
KGMEOLOC_00893 1.64e-81 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
KGMEOLOC_00894 6.21e-163 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KGMEOLOC_00895 2.35e-215 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KGMEOLOC_00896 3.3e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KGMEOLOC_00897 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
KGMEOLOC_00898 2.13e-192 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
KGMEOLOC_00899 2.47e-251 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
KGMEOLOC_00900 9.51e-296 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KGMEOLOC_00901 1.43e-82 yhcM - - - - - - -
KGMEOLOC_00902 2.3e-123 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KGMEOLOC_00903 6.91e-201 yhcP - - - - - - -
KGMEOLOC_00904 8.36e-154 yhcQ - - M - - - Spore coat protein
KGMEOLOC_00905 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KGMEOLOC_00906 8.19e-140 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
KGMEOLOC_00907 5.19e-222 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
KGMEOLOC_00908 1.88e-92 yhcU - - S - - - Family of unknown function (DUF5365)
KGMEOLOC_00909 6.12e-91 yhcV - - S - - - COG0517 FOG CBS domain
KGMEOLOC_00910 3.41e-161 yhcW - - S ko:K07025 - ko00000 hydrolase
KGMEOLOC_00911 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KGMEOLOC_00912 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KGMEOLOC_00913 5.16e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KGMEOLOC_00914 2.83e-199 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KGMEOLOC_00915 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KGMEOLOC_00916 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KGMEOLOC_00917 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
KGMEOLOC_00918 2.18e-267 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
KGMEOLOC_00919 3.15e-145 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KGMEOLOC_00920 1.76e-118 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
KGMEOLOC_00921 6.98e-53 yhdB - - S - - - YhdB-like protein
KGMEOLOC_00922 1.46e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
KGMEOLOC_00923 1.27e-298 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
KGMEOLOC_00924 3.25e-97 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
KGMEOLOC_00925 0.0 ygxB - - M - - - Conserved TM helix
KGMEOLOC_00926 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
KGMEOLOC_00927 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
KGMEOLOC_00928 5.53e-178 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
KGMEOLOC_00929 7e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
KGMEOLOC_00930 5.96e-264 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
KGMEOLOC_00931 2.73e-206 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGMEOLOC_00932 8.9e-317 yhdG - - E ko:K03294 - ko00000 amino acid
KGMEOLOC_00933 1.78e-268 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KGMEOLOC_00934 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
KGMEOLOC_00935 1.69e-257 yhdL - - S - - - Sigma factor regulator N-terminal
KGMEOLOC_00936 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KGMEOLOC_00937 1.59e-142 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KGMEOLOC_00938 3.94e-307 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
KGMEOLOC_00939 1.19e-93 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
KGMEOLOC_00940 1.47e-288 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
KGMEOLOC_00941 2.84e-303 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KGMEOLOC_00942 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
KGMEOLOC_00943 2.12e-72 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KGMEOLOC_00944 4.27e-89 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KGMEOLOC_00945 1.97e-169 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
KGMEOLOC_00946 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
KGMEOLOC_00947 6.68e-262 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
KGMEOLOC_00948 7.18e-181 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KGMEOLOC_00949 1.46e-202 nodB1 - - G - - - deacetylase
KGMEOLOC_00950 1.24e-199 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
KGMEOLOC_00951 1.22e-114 pksA - - K - - - Transcriptional regulator
KGMEOLOC_00952 1.23e-115 ymcC - - S - - - Membrane
KGMEOLOC_00953 4.31e-111 - - - T - - - universal stress protein
KGMEOLOC_00955 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KGMEOLOC_00956 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KGMEOLOC_00957 7.39e-114 yheG - - GM - - - NAD(P)H-binding
KGMEOLOC_00959 1.15e-39 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
KGMEOLOC_00960 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
KGMEOLOC_00961 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
KGMEOLOC_00962 1.32e-273 yheC - - HJ - - - YheC/D like ATP-grasp
KGMEOLOC_00963 2.01e-266 yheB - - S - - - Belongs to the UPF0754 family
KGMEOLOC_00964 9.85e-72 yheA - - S - - - Belongs to the UPF0342 family
KGMEOLOC_00965 1.82e-260 yhaZ - - L - - - DNA alkylation repair enzyme
KGMEOLOC_00966 1.03e-205 yhaX - - S - - - haloacid dehalogenase-like hydrolase
KGMEOLOC_00967 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
KGMEOLOC_00968 0.0 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
KGMEOLOC_00969 4.58e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
KGMEOLOC_00971 6.34e-179 yhaR - - I - - - enoyl-CoA hydratase
KGMEOLOC_00972 5.99e-21 - - - S - - - YhzD-like protein
KGMEOLOC_00973 4.49e-42 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KGMEOLOC_00974 5.03e-161 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KGMEOLOC_00975 3.55e-279 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
KGMEOLOC_00976 9.48e-303 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
KGMEOLOC_00977 0.0 yhaN - - L - - - AAA domain
KGMEOLOC_00978 4.29e-227 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
KGMEOLOC_00979 3.48e-44 yhaL - - S - - - Sporulation protein YhaL
KGMEOLOC_00980 5.57e-187 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KGMEOLOC_00981 1.29e-123 yhaK - - S - - - Putative zincin peptidase
KGMEOLOC_00982 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
KGMEOLOC_00983 8.17e-147 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
KGMEOLOC_00984 4.74e-55 yhaH - - S - - - YtxH-like protein
KGMEOLOC_00985 2.55e-24 - - - - - - - -
KGMEOLOC_00986 1.43e-100 trpP - - S - - - Tryptophan transporter TrpP
KGMEOLOC_00987 5.28e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KGMEOLOC_00988 5.82e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KGMEOLOC_00989 1.82e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
KGMEOLOC_00990 7.81e-282 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
KGMEOLOC_00991 6.35e-164 ecsC - - S - - - EcsC protein family
KGMEOLOC_00992 2.26e-288 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KGMEOLOC_00993 1.05e-159 yhfA - - C - - - membrane
KGMEOLOC_00994 4.58e-119 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
KGMEOLOC_00995 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KGMEOLOC_00996 2.2e-260 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KGMEOLOC_00997 7.76e-233 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
KGMEOLOC_00998 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KGMEOLOC_00999 3.1e-131 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
KGMEOLOC_01000 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
KGMEOLOC_01001 5.92e-235 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KGMEOLOC_01003 5.41e-253 yhfE - - G - - - peptidase M42
KGMEOLOC_01004 3.36e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KGMEOLOC_01005 1.7e-182 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
KGMEOLOC_01006 3.9e-243 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
KGMEOLOC_01007 1.14e-145 yhfK - - GM - - - NmrA-like family
KGMEOLOC_01008 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
KGMEOLOC_01009 2.38e-86 yhfM - - - - - - -
KGMEOLOC_01010 0.000564 yhfN - - O - - - Peptidase M48
KGMEOLOC_01011 3.18e-228 yhfN - - O - - - Peptidase M48
KGMEOLOC_01012 3.46e-265 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KGMEOLOC_01013 6.52e-200 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
KGMEOLOC_01014 4.42e-136 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
KGMEOLOC_01015 8.08e-259 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
KGMEOLOC_01016 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
KGMEOLOC_01017 1.86e-116 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
KGMEOLOC_01018 1.18e-278 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
KGMEOLOC_01019 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
KGMEOLOC_01020 1.35e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGMEOLOC_01021 5.7e-44 yhzC - - S - - - IDEAL
KGMEOLOC_01022 7.64e-142 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
KGMEOLOC_01023 1.79e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
KGMEOLOC_01024 8.17e-90 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
KGMEOLOC_01025 3.6e-122 - - - S - - - MepB protein
KGMEOLOC_01026 8e-166 yrpD - - S - - - Domain of unknown function, YrpD
KGMEOLOC_01027 1.23e-57 yhjA - - S - - - Excalibur calcium-binding domain
KGMEOLOC_01028 2.2e-68 - - - S - - - Belongs to the UPF0145 family
KGMEOLOC_01029 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KGMEOLOC_01030 1.37e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
KGMEOLOC_01031 4.12e-79 yhjD - - - - - - -
KGMEOLOC_01032 2.83e-145 yhjE - - S - - - SNARE associated Golgi protein
KGMEOLOC_01033 3.32e-119 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KGMEOLOC_01034 0.0 yhjG - - CH - - - FAD binding domain
KGMEOLOC_01035 1.03e-123 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
KGMEOLOC_01036 4.19e-263 yhjN - - S ko:K07120 - ko00000 membrane
KGMEOLOC_01037 2.27e-269 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
KGMEOLOC_01038 2.72e-142 - - - K - - - QacR-like protein, C-terminal region
KGMEOLOC_01039 4.38e-123 yhjR - - S - - - Rubrerythrin
KGMEOLOC_01040 1.81e-162 ydfS - - S - - - Protein of unknown function (DUF421)
KGMEOLOC_01041 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
KGMEOLOC_01042 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
KGMEOLOC_01043 5.72e-284 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KGMEOLOC_01044 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
KGMEOLOC_01045 2.64e-67 yisB - - V - - - COG1403 Restriction endonuclease
KGMEOLOC_01046 6.66e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
KGMEOLOC_01047 1.67e-86 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
KGMEOLOC_01048 3e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
KGMEOLOC_01049 8.51e-109 gerPC - - S ko:K06301 - ko00000 Spore germination protein
KGMEOLOC_01050 6.59e-48 gerPB - - S ko:K06300 - ko00000 cell differentiation
KGMEOLOC_01051 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
KGMEOLOC_01052 2.25e-11 yisI - - S - - - Spo0E like sporulation regulatory protein
KGMEOLOC_01053 1.13e-220 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KGMEOLOC_01054 2.22e-78 yisL - - S - - - UPF0344 protein
KGMEOLOC_01055 2.35e-127 yisN - - S - - - Protein of unknown function (DUF2777)
KGMEOLOC_01056 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KGMEOLOC_01057 1.19e-174 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
KGMEOLOC_01058 2.14e-312 yisQ - - V - - - Mate efflux family protein
KGMEOLOC_01059 4.22e-209 yisR - - K - - - Transcriptional regulator
KGMEOLOC_01060 5.37e-117 yisT - - S - - - DinB family
KGMEOLOC_01061 1.42e-113 yisX - - S - - - Pentapeptide repeats (9 copies)
KGMEOLOC_01062 3.78e-106 - - - S - - - Acetyltransferase (GNAT) domain
KGMEOLOC_01063 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KGMEOLOC_01064 6.39e-79 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
KGMEOLOC_01065 1.59e-206 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
KGMEOLOC_01066 9.67e-225 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
KGMEOLOC_01067 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
KGMEOLOC_01068 5.82e-313 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
KGMEOLOC_01070 9.52e-204 yitS - - S - - - protein conserved in bacteria
KGMEOLOC_01071 1.61e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KGMEOLOC_01072 6.41e-106 ipi - - S - - - Intracellular proteinase inhibitor
KGMEOLOC_01073 1.5e-36 - - - S - - - Protein of unknown function (DUF3813)
KGMEOLOC_01074 1.49e-11 - - - - - - - -
KGMEOLOC_01075 1.52e-198 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
KGMEOLOC_01076 9.1e-188 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
KGMEOLOC_01077 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
KGMEOLOC_01078 1.42e-106 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
KGMEOLOC_01079 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
KGMEOLOC_01080 1.18e-121 yitZ - - G - - - Major Facilitator Superfamily
KGMEOLOC_01081 9.02e-256 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KGMEOLOC_01082 5.39e-292 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KGMEOLOC_01083 1.88e-177 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
KGMEOLOC_01084 1.19e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
KGMEOLOC_01085 1.69e-259 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KGMEOLOC_01086 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
KGMEOLOC_01087 3.09e-227 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KGMEOLOC_01088 7.21e-39 yjzC - - S - - - YjzC-like protein
KGMEOLOC_01089 5.24e-33 yjzD - - S - - - Protein of unknown function (DUF2929)
KGMEOLOC_01090 1.4e-181 yjaU - - I - - - carboxylic ester hydrolase activity
KGMEOLOC_01091 2.12e-137 yjaV - - - - - - -
KGMEOLOC_01092 4.67e-213 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
KGMEOLOC_01093 6.46e-37 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
KGMEOLOC_01094 2.82e-44 yjzB - - - - - - -
KGMEOLOC_01095 3.78e-220 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KGMEOLOC_01096 2.71e-300 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KGMEOLOC_01097 1.84e-190 yjaZ - - O - - - Zn-dependent protease
KGMEOLOC_01098 7.17e-233 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KGMEOLOC_01099 8.8e-239 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KGMEOLOC_01100 3.29e-277 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
KGMEOLOC_01101 8.6e-113 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
KGMEOLOC_01102 4.24e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGMEOLOC_01103 3.87e-209 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGMEOLOC_01104 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
KGMEOLOC_01105 8.74e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
KGMEOLOC_01106 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KGMEOLOC_01107 2.53e-213 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGMEOLOC_01108 3.59e-210 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGMEOLOC_01109 1.5e-256 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KGMEOLOC_01110 2.19e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KGMEOLOC_01111 1.5e-299 - - - S - - - Putative glycosyl hydrolase domain
KGMEOLOC_01112 4.4e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KGMEOLOC_01113 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KGMEOLOC_01114 1.18e-142 yjbE - - P - - - Integral membrane protein TerC family
KGMEOLOC_01115 9.78e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KGMEOLOC_01116 4.36e-286 coiA - - S ko:K06198 - ko00000 Competence protein
KGMEOLOC_01117 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
KGMEOLOC_01118 3.14e-27 - - - - - - - -
KGMEOLOC_01119 1.49e-220 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
KGMEOLOC_01120 1.22e-93 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
KGMEOLOC_01121 1.32e-153 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KGMEOLOC_01122 4.41e-131 yjbK - - S - - - protein conserved in bacteria
KGMEOLOC_01123 3.5e-81 yjbL - - S - - - Belongs to the UPF0738 family
KGMEOLOC_01124 1.56e-139 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
KGMEOLOC_01125 2.07e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KGMEOLOC_01126 8.54e-214 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
KGMEOLOC_01127 5.48e-186 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
KGMEOLOC_01128 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KGMEOLOC_01129 4.88e-178 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KGMEOLOC_01130 8.09e-139 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
KGMEOLOC_01131 6.85e-279 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
KGMEOLOC_01132 5.5e-42 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
KGMEOLOC_01133 1.81e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KGMEOLOC_01134 8.18e-243 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KGMEOLOC_01135 4.49e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KGMEOLOC_01136 1.68e-180 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
KGMEOLOC_01137 2.9e-126 yjbX - - S - - - Spore coat protein
KGMEOLOC_01138 1.79e-109 cotZ - - S ko:K06344 - ko00000 Spore coat protein
KGMEOLOC_01139 5.2e-122 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
KGMEOLOC_01140 2.33e-103 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
KGMEOLOC_01141 1.98e-36 cotW - - - ko:K06341 - ko00000 -
KGMEOLOC_01142 3.02e-74 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
KGMEOLOC_01143 1.24e-74 yjcA - - S - - - Protein of unknown function (DUF1360)
KGMEOLOC_01145 5.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
KGMEOLOC_01146 2.57e-51 spoVIF - - S - - - Stage VI sporulation protein F
KGMEOLOC_01147 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KGMEOLOC_01148 1.49e-49 - - - - - - - -
KGMEOLOC_01149 1.57e-185 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
KGMEOLOC_01150 1.13e-160 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
KGMEOLOC_01151 2.48e-171 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
KGMEOLOC_01152 4.32e-48 - - - K - - - SpoVT / AbrB like domain
KGMEOLOC_01153 3.66e-98 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KGMEOLOC_01154 2.43e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
KGMEOLOC_01155 8.63e-165 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
KGMEOLOC_01156 3.37e-272 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KGMEOLOC_01157 2.82e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KGMEOLOC_01159 1.14e-41 - - - - - - - -
KGMEOLOC_01160 3.47e-111 - - - - - - - -
KGMEOLOC_01161 1.5e-122 - - - L ko:K21487 - ko00000,ko01000,ko02048 Belongs to the WXG100 family
KGMEOLOC_01162 4.26e-120 - - - L ko:K21487 - ko00000,ko01000,ko02048 Belongs to the WXG100 family
KGMEOLOC_01164 1.76e-108 - - - - - - - -
KGMEOLOC_01166 2.43e-18 - - - - - - - -
KGMEOLOC_01167 6.79e-06 - - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
KGMEOLOC_01168 1.05e-75 - - - - - - - -
KGMEOLOC_01169 7.84e-100 - - - S - - - Bacterial EndoU nuclease
KGMEOLOC_01170 2.72e-119 - - - S - - - Bacterial EndoU nuclease
KGMEOLOC_01171 1.18e-122 - - - - - - - -
KGMEOLOC_01174 1.7e-176 - - - - - - - -
KGMEOLOC_01177 1.13e-217 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
KGMEOLOC_01178 2.2e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
KGMEOLOC_01179 0.0 yfjF - - EGP - - - Belongs to the major facilitator superfamily
KGMEOLOC_01180 3.68e-107 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KGMEOLOC_01181 8.39e-285 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
KGMEOLOC_01182 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
KGMEOLOC_01183 3.61e-243 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KGMEOLOC_01184 3.42e-280 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KGMEOLOC_01185 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KGMEOLOC_01186 8.91e-67 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KGMEOLOC_01187 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KGMEOLOC_01188 1.02e-179 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
KGMEOLOC_01189 1.29e-164 - - - S - - - Haloacid dehalogenase-like hydrolase
KGMEOLOC_01190 2.14e-192 - - - N - - - Kelch motif
KGMEOLOC_01192 2.48e-136 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
KGMEOLOC_01194 1.91e-31 yjfB - - S - - - Putative motility protein
KGMEOLOC_01195 1.87e-93 yjgA - - T - - - Protein of unknown function (DUF2809)
KGMEOLOC_01196 6.05e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
KGMEOLOC_01197 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
KGMEOLOC_01198 2.2e-117 yjgD - - S - - - Protein of unknown function (DUF1641)
KGMEOLOC_01199 7.66e-292 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KGMEOLOC_01200 2.64e-287 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KGMEOLOC_01201 1.73e-40 - - - - - - - -
KGMEOLOC_01202 1.43e-187 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
KGMEOLOC_01203 3.55e-159 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
KGMEOLOC_01204 4.76e-170 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
KGMEOLOC_01205 7.42e-230 yjlA - - EG - - - Putative multidrug resistance efflux transporter
KGMEOLOC_01206 8.91e-121 yjlB - - S - - - Cupin domain
KGMEOLOC_01207 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
KGMEOLOC_01208 7.49e-281 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KGMEOLOC_01209 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
KGMEOLOC_01210 0.0 - - - G ko:K03292 - ko00000 symporter YjmB
KGMEOLOC_01211 1.24e-235 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
KGMEOLOC_01212 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
KGMEOLOC_01213 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
KGMEOLOC_01214 3.21e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
KGMEOLOC_01215 4.32e-105 yjoA - - S - - - DinB family
KGMEOLOC_01216 2.68e-275 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
KGMEOLOC_01218 8.26e-222 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
KGMEOLOC_01219 9.51e-81 yjqA - - S - - - Bacterial PH domain
KGMEOLOC_01220 7.87e-144 yjqB - - S - - - phage-related replication protein
KGMEOLOC_01221 6.51e-145 xkdA - - E - - - IrrE N-terminal-like domain
KGMEOLOC_01222 6.52e-75 xre - - K - - - Helix-turn-helix XRE-family like proteins
KGMEOLOC_01224 1.69e-22 xkdB - - K - - - sequence-specific DNA binding
KGMEOLOC_01225 9.14e-198 xkdC - - L - - - Bacterial dnaA protein
KGMEOLOC_01229 1.07e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
KGMEOLOC_01230 1.24e-47 xtmA - - - ko:K07474 - ko00000 -
KGMEOLOC_01231 9.95e-50 - - - - - - - -
KGMEOLOC_01233 5.6e-41 xkdX - - - - - - -
KGMEOLOC_01234 7.18e-184 xepA - - - - - - -
KGMEOLOC_01235 3.87e-51 xhlA - - S - - - Haemolysin XhlA
KGMEOLOC_01236 4.7e-52 xhlB - - S - - - SPP1 phage holin
KGMEOLOC_01237 5.16e-217 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
KGMEOLOC_01238 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
KGMEOLOC_01239 2.79e-174 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
KGMEOLOC_01240 8.61e-227 pit - - P ko:K03306 - ko00000 phosphate transporter
KGMEOLOC_01241 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
KGMEOLOC_01242 2.3e-312 steT - - E ko:K03294 - ko00000 amino acid
KGMEOLOC_01243 3.43e-234 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
KGMEOLOC_01244 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KGMEOLOC_01245 6.62e-231 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
KGMEOLOC_01247 2.36e-279 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KGMEOLOC_01248 0.0 yubD - - P - - - Major Facilitator Superfamily
KGMEOLOC_01250 4.36e-200 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
KGMEOLOC_01251 2.4e-205 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGMEOLOC_01252 6.59e-227 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGMEOLOC_01253 6.75e-245 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KGMEOLOC_01254 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KGMEOLOC_01255 5.87e-228 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
KGMEOLOC_01256 4.18e-262 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
KGMEOLOC_01257 2.89e-222 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KGMEOLOC_01258 1.39e-232 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KGMEOLOC_01259 1.46e-263 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
KGMEOLOC_01260 4.37e-206 ykgA - - E - - - Amidinotransferase
KGMEOLOC_01261 2.16e-120 ykhA - - I - - - Acyl-CoA hydrolase
KGMEOLOC_01262 1.34e-132 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KGMEOLOC_01263 7.06e-70 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
KGMEOLOC_01264 1.04e-65 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
KGMEOLOC_01265 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
KGMEOLOC_01266 3.73e-263 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KGMEOLOC_01267 1.37e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KGMEOLOC_01268 5.88e-94 ohrA - - O - - - Organic hydroperoxide resistance protein
KGMEOLOC_01269 7.54e-115 ohrR - - K - - - COG1846 Transcriptional regulators
KGMEOLOC_01270 1.92e-92 ohrB - - O - - - Organic hydroperoxide resistance protein
KGMEOLOC_01271 1.83e-86 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KGMEOLOC_01273 1.82e-277 - - - M - - - Glycosyl transferase family 2
KGMEOLOC_01274 1.72e-192 - - - M - - - PFAM Collagen triple helix repeat (20 copies)
KGMEOLOC_01275 4.16e-279 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KGMEOLOC_01276 2.53e-161 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KGMEOLOC_01277 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KGMEOLOC_01278 1.09e-227 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KGMEOLOC_01279 5.66e-193 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KGMEOLOC_01280 6.53e-171 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
KGMEOLOC_01281 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KGMEOLOC_01282 1.19e-128 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
KGMEOLOC_01283 1.13e-312 ydhD - - M - - - Glycosyl hydrolase
KGMEOLOC_01285 8.66e-310 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
KGMEOLOC_01286 1.23e-69 tnrA - - K - - - transcriptional
KGMEOLOC_01287 1.11e-23 - - - - - - - -
KGMEOLOC_01288 5.25e-37 ykoL - - - - - - -
KGMEOLOC_01289 5.46e-105 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
KGMEOLOC_01290 3.81e-129 ykoP - - G - - - polysaccharide deacetylase
KGMEOLOC_01291 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
KGMEOLOC_01292 3.42e-202 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KGMEOLOC_01293 1.43e-131 ykoX - - S - - - membrane-associated protein
KGMEOLOC_01294 3.54e-174 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KGMEOLOC_01295 9.83e-93 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KGMEOLOC_01296 1.35e-26 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KGMEOLOC_01297 2.53e-250 ykrI - - S - - - Anti-sigma factor N-terminus
KGMEOLOC_01298 5.7e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
KGMEOLOC_01299 6.86e-163 ykrK - - S - - - Domain of unknown function (DUF1836)
KGMEOLOC_01300 6.35e-200 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
KGMEOLOC_01301 1.62e-309 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
KGMEOLOC_01302 1.74e-149 - - - S - - - Protein of unknown function (DUF421)
KGMEOLOC_01303 4.95e-246 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
KGMEOLOC_01304 4.12e-79 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KGMEOLOC_01305 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KGMEOLOC_01306 1.17e-116 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KGMEOLOC_01308 9.34e-253 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KGMEOLOC_01309 1.04e-288 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KGMEOLOC_01310 9.87e-194 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KGMEOLOC_01311 7.65e-293 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KGMEOLOC_01312 4.05e-291 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
KGMEOLOC_01313 1.4e-176 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KGMEOLOC_01314 2.33e-149 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
KGMEOLOC_01315 6.37e-125 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KGMEOLOC_01317 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
KGMEOLOC_01318 3.34e-101 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
KGMEOLOC_01319 4.04e-169 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
KGMEOLOC_01320 7.27e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
KGMEOLOC_01321 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
KGMEOLOC_01322 6.6e-233 ykvI - - S - - - membrane
KGMEOLOC_01323 2.05e-257 - - - - - - - -
KGMEOLOC_01324 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KGMEOLOC_01325 8.23e-106 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
KGMEOLOC_01326 1.76e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KGMEOLOC_01327 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KGMEOLOC_01329 6.24e-78 ykvN - - K - - - Transcriptional regulator
KGMEOLOC_01330 1.89e-172 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KGMEOLOC_01331 3.24e-44 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KGMEOLOC_01332 4.38e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
KGMEOLOC_01333 5.43e-35 ykvS - - S - - - protein conserved in bacteria
KGMEOLOC_01334 7.17e-39 - - - - - - - -
KGMEOLOC_01335 1.77e-143 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
KGMEOLOC_01336 2.66e-306 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KGMEOLOC_01337 6.28e-116 stoA - - CO - - - thiol-disulfide
KGMEOLOC_01338 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
KGMEOLOC_01339 9.91e-265 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
KGMEOLOC_01341 2.12e-226 ykvZ - - K - - - Transcriptional regulator
KGMEOLOC_01342 2.78e-199 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
KGMEOLOC_01343 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KGMEOLOC_01344 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
KGMEOLOC_01345 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KGMEOLOC_01346 3.63e-50 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
KGMEOLOC_01347 3.53e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
KGMEOLOC_01348 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KGMEOLOC_01349 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KGMEOLOC_01350 4.13e-86 - - - - - - - -
KGMEOLOC_01351 2.37e-177 ykwD - - J - - - protein with SCP PR1 domains
KGMEOLOC_01352 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KGMEOLOC_01353 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KGMEOLOC_01354 2.81e-276 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KGMEOLOC_01355 6.38e-15 - - - - - - - -
KGMEOLOC_01356 4.07e-215 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
KGMEOLOC_01357 5.07e-108 ykyB - - S - - - YkyB-like protein
KGMEOLOC_01358 9.69e-310 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KGMEOLOC_01359 8.88e-117 ykuD - - S - - - protein conserved in bacteria
KGMEOLOC_01360 1.02e-203 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
KGMEOLOC_01361 1.06e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGMEOLOC_01362 7.72e-297 ykuI - - T - - - Diguanylate phosphodiesterase
KGMEOLOC_01363 3.63e-50 ykuJ - - S - - - protein conserved in bacteria
KGMEOLOC_01364 5.29e-121 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
KGMEOLOC_01365 4.54e-37 ykzF - - S - - - Antirepressor AbbA
KGMEOLOC_01366 8.55e-99 ykuL - - S - - - CBS domain
KGMEOLOC_01367 1.32e-215 ccpC - - K - - - Transcriptional regulator
KGMEOLOC_01368 3.15e-117 ykuN - - C ko:K03839 - ko00000 Flavodoxin
KGMEOLOC_01369 2.47e-222 ykuO - - - - - - -
KGMEOLOC_01370 3.19e-105 fld - - C ko:K03839 - ko00000 Flavodoxin
KGMEOLOC_01371 2.49e-130 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KGMEOLOC_01372 2.39e-277 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KGMEOLOC_01373 2.15e-52 ykuS - - S - - - Belongs to the UPF0180 family
KGMEOLOC_01374 1.54e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
KGMEOLOC_01375 8.45e-106 ykuV - - CO - - - thiol-disulfide
KGMEOLOC_01376 7.46e-127 rok - - K - - - Repressor of ComK
KGMEOLOC_01377 2.53e-218 yknT - - - ko:K06437 - ko00000 -
KGMEOLOC_01378 5.6e-17 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KGMEOLOC_01379 2.83e-115 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KGMEOLOC_01380 1.71e-241 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KGMEOLOC_01381 1.29e-314 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
KGMEOLOC_01382 3.21e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
KGMEOLOC_01383 7.17e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
KGMEOLOC_01384 2.06e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KGMEOLOC_01385 7.2e-144 yknW - - S - - - Yip1 domain
KGMEOLOC_01386 2e-246 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KGMEOLOC_01387 3.09e-133 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KGMEOLOC_01388 1.09e-271 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
KGMEOLOC_01389 1.18e-172 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
KGMEOLOC_01390 4.75e-214 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
KGMEOLOC_01391 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KGMEOLOC_01392 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KGMEOLOC_01393 4.47e-51 ykoA - - - - - - -
KGMEOLOC_01394 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KGMEOLOC_01395 1.6e-216 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KGMEOLOC_01396 2.95e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
KGMEOLOC_01397 6.35e-18 - - - S - - - Uncharacterized protein YkpC
KGMEOLOC_01398 1.11e-167 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
KGMEOLOC_01399 1.5e-54 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
KGMEOLOC_01400 6.37e-60 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
KGMEOLOC_01401 5.87e-313 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
KGMEOLOC_01402 1.58e-198 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
KGMEOLOC_01403 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
KGMEOLOC_01404 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KGMEOLOC_01405 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KGMEOLOC_01406 4.45e-42 ykzG - - S - - - Belongs to the UPF0356 family
KGMEOLOC_01407 5.48e-190 ykrA - - S - - - hydrolases of the HAD superfamily
KGMEOLOC_01408 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KGMEOLOC_01409 1.08e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
KGMEOLOC_01410 1.88e-136 ykyA - - L - - - Putative cell-wall binding lipoprotein
KGMEOLOC_01411 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KGMEOLOC_01412 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KGMEOLOC_01413 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KGMEOLOC_01414 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KGMEOLOC_01415 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 polyketide synthase
KGMEOLOC_01416 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KGMEOLOC_01417 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KGMEOLOC_01418 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KGMEOLOC_01419 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KGMEOLOC_01420 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KGMEOLOC_01421 0.0 - - - IQ - - - Phosphopantetheine attachment site
KGMEOLOC_01422 8.9e-272 - - - V - - - Beta-lactamase
KGMEOLOC_01423 6.68e-262 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KGMEOLOC_01424 1.01e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KGMEOLOC_01425 7.27e-302 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KGMEOLOC_01426 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KGMEOLOC_01427 7.97e-59 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
KGMEOLOC_01428 4.87e-193 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
KGMEOLOC_01429 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
KGMEOLOC_01430 9.4e-57 yktA - - S - - - Belongs to the UPF0223 family
KGMEOLOC_01431 8.15e-155 yktB - - S - - - Belongs to the UPF0637 family
KGMEOLOC_01432 3.33e-33 ykzI - - - - - - -
KGMEOLOC_01433 9.88e-197 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
KGMEOLOC_01434 1.3e-108 ykzC - - S - - - Acetyltransferase (GNAT) family
KGMEOLOC_01435 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
KGMEOLOC_01436 2.3e-255 ylaA - - - - - - -
KGMEOLOC_01437 5.66e-184 - - - - - - - -
KGMEOLOC_01438 5.38e-61 ylaB - - - - - - -
KGMEOLOC_01439 8.11e-121 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KGMEOLOC_01441 3.48e-63 ylaE - - - - - - -
KGMEOLOC_01442 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
KGMEOLOC_01443 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
KGMEOLOC_01444 2.44e-65 - - - S - - - YlaH-like protein
KGMEOLOC_01445 6.78e-46 ylaI - - S - - - protein conserved in bacteria
KGMEOLOC_01446 5.45e-138 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KGMEOLOC_01447 8.09e-315 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
KGMEOLOC_01448 3.02e-111 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KGMEOLOC_01449 6.57e-224 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
KGMEOLOC_01450 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
KGMEOLOC_01451 1.05e-272 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KGMEOLOC_01452 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KGMEOLOC_01453 3.47e-214 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
KGMEOLOC_01454 2.07e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KGMEOLOC_01455 3.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
KGMEOLOC_01456 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KGMEOLOC_01457 5.92e-142 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
KGMEOLOC_01458 3.53e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
KGMEOLOC_01459 5.32e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
KGMEOLOC_01460 1.75e-80 ylbA - - S - - - YugN-like family
KGMEOLOC_01461 3.35e-96 ylbB - - T - - - COG0517 FOG CBS domain
KGMEOLOC_01462 2.8e-255 ylbC - - S - - - protein with SCP PR1 domains
KGMEOLOC_01463 1.52e-89 ylbD - - S - - - Putative coat protein
KGMEOLOC_01464 1.73e-48 ylbE - - S - - - YlbE-like protein
KGMEOLOC_01465 3.33e-97 ylbF - - S - - - Belongs to the UPF0342 family
KGMEOLOC_01466 2.78e-57 ylbG - - S - - - UPF0298 protein
KGMEOLOC_01468 7.68e-116 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
KGMEOLOC_01469 1.01e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KGMEOLOC_01470 1.02e-277 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
KGMEOLOC_01471 1.23e-178 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
KGMEOLOC_01472 5.31e-241 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
KGMEOLOC_01473 1.34e-297 ylbM - - S - - - Belongs to the UPF0348 family
KGMEOLOC_01474 1.7e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
KGMEOLOC_01475 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
KGMEOLOC_01476 1.33e-112 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
KGMEOLOC_01477 1.38e-117 ylbP - - K - - - n-acetyltransferase
KGMEOLOC_01478 6.13e-213 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KGMEOLOC_01479 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KGMEOLOC_01480 1.78e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
KGMEOLOC_01481 3.5e-220 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KGMEOLOC_01482 2.4e-68 ftsL - - D - - - Essential cell division protein
KGMEOLOC_01483 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KGMEOLOC_01484 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
KGMEOLOC_01485 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KGMEOLOC_01486 7.04e-222 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KGMEOLOC_01487 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KGMEOLOC_01488 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KGMEOLOC_01489 5.69e-259 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KGMEOLOC_01490 1.17e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
KGMEOLOC_01491 9.33e-180 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KGMEOLOC_01492 1.57e-298 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KGMEOLOC_01493 2.61e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KGMEOLOC_01495 1.04e-45 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
KGMEOLOC_01496 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
KGMEOLOC_01497 2.02e-218 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
KGMEOLOC_01498 7.35e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KGMEOLOC_01499 9.33e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KGMEOLOC_01500 2.06e-189 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
KGMEOLOC_01501 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
KGMEOLOC_01502 7.13e-52 ylmC - - S - - - sporulation protein
KGMEOLOC_01503 5.76e-207 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
KGMEOLOC_01504 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KGMEOLOC_01505 7.98e-86 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KGMEOLOC_01506 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
KGMEOLOC_01507 6.12e-182 ylmH - - S - - - conserved protein, contains S4-like domain
KGMEOLOC_01508 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
KGMEOLOC_01509 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KGMEOLOC_01510 6.48e-87 ylyA - - T - - - COG1734 DnaK suppressor protein
KGMEOLOC_01511 1.24e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KGMEOLOC_01512 2.65e-216 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KGMEOLOC_01513 2.21e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KGMEOLOC_01514 3.42e-297 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
KGMEOLOC_01515 6.51e-217 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
KGMEOLOC_01516 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KGMEOLOC_01517 3.09e-268 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KGMEOLOC_01518 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
KGMEOLOC_01519 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KGMEOLOC_01520 7.67e-224 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KGMEOLOC_01521 3.66e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KGMEOLOC_01522 2.2e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KGMEOLOC_01524 9.88e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
KGMEOLOC_01525 8.54e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
KGMEOLOC_01526 4.53e-286 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
KGMEOLOC_01527 6.76e-143 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
KGMEOLOC_01528 2.06e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
KGMEOLOC_01529 1.76e-188 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
KGMEOLOC_01530 2.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
KGMEOLOC_01531 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
KGMEOLOC_01532 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
KGMEOLOC_01533 1.77e-206 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
KGMEOLOC_01534 1.51e-198 yloC - - S - - - stress-induced protein
KGMEOLOC_01535 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
KGMEOLOC_01536 4.91e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
KGMEOLOC_01537 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KGMEOLOC_01538 9.26e-289 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KGMEOLOC_01539 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KGMEOLOC_01540 5e-111 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KGMEOLOC_01541 1.44e-20 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KGMEOLOC_01542 1.95e-195 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KGMEOLOC_01543 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KGMEOLOC_01544 1.52e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KGMEOLOC_01545 5.2e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
KGMEOLOC_01546 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
KGMEOLOC_01547 1.08e-211 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KGMEOLOC_01548 6.15e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
KGMEOLOC_01549 6.68e-156 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
KGMEOLOC_01550 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
KGMEOLOC_01551 3.65e-78 yloU - - S - - - protein conserved in bacteria
KGMEOLOC_01552 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
KGMEOLOC_01553 4.15e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
KGMEOLOC_01554 4.14e-202 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
KGMEOLOC_01555 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KGMEOLOC_01556 4.38e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
KGMEOLOC_01557 7.71e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KGMEOLOC_01558 3.22e-219 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KGMEOLOC_01559 8.61e-168 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
KGMEOLOC_01560 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
KGMEOLOC_01561 3.02e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KGMEOLOC_01562 1.13e-132 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
KGMEOLOC_01563 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
KGMEOLOC_01564 2.28e-225 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KGMEOLOC_01565 1.34e-185 - - - S - - - Phosphotransferase enzyme family
KGMEOLOC_01566 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KGMEOLOC_01567 1.6e-292 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KGMEOLOC_01568 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
KGMEOLOC_01569 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
KGMEOLOC_01570 3.41e-80 ylqD - - S - - - YlqD protein
KGMEOLOC_01571 1.51e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KGMEOLOC_01572 2.93e-178 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
KGMEOLOC_01573 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KGMEOLOC_01574 5.09e-203 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KGMEOLOC_01575 8.29e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KGMEOLOC_01576 0.0 ylqG - - - - - - -
KGMEOLOC_01577 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
KGMEOLOC_01578 2.02e-270 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KGMEOLOC_01579 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KGMEOLOC_01580 4.8e-221 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
KGMEOLOC_01581 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KGMEOLOC_01582 3.83e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KGMEOLOC_01583 6.29e-220 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
KGMEOLOC_01584 7.38e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KGMEOLOC_01585 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KGMEOLOC_01586 2.77e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KGMEOLOC_01587 2.8e-84 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
KGMEOLOC_01588 2.63e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
KGMEOLOC_01589 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
KGMEOLOC_01590 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
KGMEOLOC_01591 2.48e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KGMEOLOC_01592 4.35e-126 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
KGMEOLOC_01593 5.19e-309 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
KGMEOLOC_01594 2.17e-92 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
KGMEOLOC_01595 3.43e-89 ylxF - - S - - - MgtE intracellular N domain
KGMEOLOC_01596 1.72e-266 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
KGMEOLOC_01597 1.54e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
KGMEOLOC_01598 2.79e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
KGMEOLOC_01599 6.59e-81 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
KGMEOLOC_01600 5.43e-230 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KGMEOLOC_01601 1.08e-250 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KGMEOLOC_01602 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
KGMEOLOC_01603 9.34e-144 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
KGMEOLOC_01604 1.48e-142 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
KGMEOLOC_01605 3.15e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
KGMEOLOC_01606 5.74e-168 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
KGMEOLOC_01607 2.53e-242 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KGMEOLOC_01608 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KGMEOLOC_01609 3.37e-251 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
KGMEOLOC_01610 5.68e-203 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
KGMEOLOC_01611 4.97e-249 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
KGMEOLOC_01612 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
KGMEOLOC_01613 2.49e-105 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
KGMEOLOC_01614 1.45e-143 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
KGMEOLOC_01615 2.86e-113 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KGMEOLOC_01616 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KGMEOLOC_01617 7.41e-97 ylxL - - - - - - -
KGMEOLOC_01618 1.74e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
KGMEOLOC_01619 1.63e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KGMEOLOC_01620 7.09e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
KGMEOLOC_01621 1.94e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KGMEOLOC_01622 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KGMEOLOC_01623 3.8e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
KGMEOLOC_01624 8.01e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KGMEOLOC_01625 9.82e-298 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
KGMEOLOC_01626 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KGMEOLOC_01627 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KGMEOLOC_01628 5.66e-106 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
KGMEOLOC_01629 4.04e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
KGMEOLOC_01630 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
KGMEOLOC_01631 6.16e-63 ylxQ - - J - - - ribosomal protein
KGMEOLOC_01632 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KGMEOLOC_01633 3.88e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
KGMEOLOC_01634 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KGMEOLOC_01635 8.95e-222 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KGMEOLOC_01636 4.5e-233 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
KGMEOLOC_01637 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KGMEOLOC_01638 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KGMEOLOC_01639 3.56e-233 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
KGMEOLOC_01640 2.51e-300 mlpA - - S - - - Belongs to the peptidase M16 family
KGMEOLOC_01641 2.17e-56 ymxH - - S - - - YlmC YmxH family
KGMEOLOC_01642 9.9e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
KGMEOLOC_01643 4.75e-138 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
KGMEOLOC_01644 1.22e-249 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KGMEOLOC_01645 2e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KGMEOLOC_01646 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KGMEOLOC_01647 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KGMEOLOC_01648 2.27e-166 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
KGMEOLOC_01649 6.32e-42 - - - S - - - YlzJ-like protein
KGMEOLOC_01650 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KGMEOLOC_01651 4.48e-172 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
KGMEOLOC_01652 2.71e-297 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KGMEOLOC_01653 1.2e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KGMEOLOC_01654 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
KGMEOLOC_01655 1.12e-306 albE - - S - - - Peptidase M16
KGMEOLOC_01656 4.28e-312 ymfH - - S - - - zinc protease
KGMEOLOC_01657 2.12e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
KGMEOLOC_01658 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
KGMEOLOC_01659 3.82e-184 ymfK - - S - - - Protein of unknown function (DUF3388)
KGMEOLOC_01660 2.46e-180 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
KGMEOLOC_01661 1.17e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KGMEOLOC_01662 8.03e-295 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
KGMEOLOC_01663 3.06e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KGMEOLOC_01664 1.34e-279 pbpX - - V - - - Beta-lactamase
KGMEOLOC_01665 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
KGMEOLOC_01666 3.72e-196 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
KGMEOLOC_01667 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
KGMEOLOC_01668 7.41e-254 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
KGMEOLOC_01669 7.42e-276 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KGMEOLOC_01670 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KGMEOLOC_01671 2.11e-88 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
KGMEOLOC_01672 7.09e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
KGMEOLOC_01673 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KGMEOLOC_01674 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KGMEOLOC_01676 1.72e-167 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
KGMEOLOC_01677 1.21e-209 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KGMEOLOC_01678 4.5e-234 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
KGMEOLOC_01679 1.89e-38 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KGMEOLOC_01680 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KGMEOLOC_01681 5.27e-49 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
KGMEOLOC_01682 6.55e-312 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
KGMEOLOC_01683 4.51e-189 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
KGMEOLOC_01684 3.42e-180 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
KGMEOLOC_01685 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
KGMEOLOC_01686 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KGMEOLOC_01687 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KGMEOLOC_01688 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KGMEOLOC_01689 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
KGMEOLOC_01690 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
KGMEOLOC_01691 4.12e-295 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KGMEOLOC_01692 1.81e-103 nucB - - M - - - Deoxyribonuclease NucA/NucB
KGMEOLOC_01693 2.21e-153 yoaK - - S - - - Membrane
KGMEOLOC_01694 2.78e-82 ymzB - - - - - - -
KGMEOLOC_01695 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
KGMEOLOC_01696 3.03e-06 - - - - - - - -
KGMEOLOC_01697 1.18e-164 ymaC - - S - - - Replication protein
KGMEOLOC_01698 7.27e-106 ymaD - - O - - - redox protein, regulator of disulfide bond formation
KGMEOLOC_01699 1.35e-68 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
KGMEOLOC_01700 1.82e-63 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
KGMEOLOC_01702 2.08e-77 ymaF - - S - - - YmaF family
KGMEOLOC_01703 7.63e-221 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KGMEOLOC_01704 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
KGMEOLOC_01705 1.47e-59 - - - - - - - -
KGMEOLOC_01706 9.42e-29 ymzA - - - - - - -
KGMEOLOC_01707 1.61e-88 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
KGMEOLOC_01708 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KGMEOLOC_01709 5.77e-244 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KGMEOLOC_01710 2.72e-142 ymaB - - S - - - MutT family
KGMEOLOC_01711 3.22e-150 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
KGMEOLOC_01712 1.55e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
KGMEOLOC_01713 1.15e-296 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KGMEOLOC_01714 1.01e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
KGMEOLOC_01715 5.34e-89 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
KGMEOLOC_01716 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
KGMEOLOC_01717 1.27e-10 - - - L - - - Arm DNA-binding domain
KGMEOLOC_01718 4.59e-21 - - - - - - - -
KGMEOLOC_01719 2.12e-123 - - - - - - - -
KGMEOLOC_01721 2.11e-275 mrjp - - G - - - Major royal jelly protein
KGMEOLOC_01722 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
KGMEOLOC_01723 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
KGMEOLOC_01724 3.29e-280 xylR - - GK - - - ROK family
KGMEOLOC_01725 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
KGMEOLOC_01726 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
KGMEOLOC_01727 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
KGMEOLOC_01732 2.21e-27 - - - - - - - -
KGMEOLOC_01733 3.03e-74 dinB - - S - - - DinB family
KGMEOLOC_01734 1.07e-239 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
KGMEOLOC_01735 2.36e-06 ywlA - - S - - - Uncharacterised protein family (UPF0715)
KGMEOLOC_01736 5.71e-190 yoaP - - K - - - YoaP-like
KGMEOLOC_01737 7.16e-132 - - - J - - - Acetyltransferase (GNAT) domain
KGMEOLOC_01738 1.25e-97 - - - - - - - -
KGMEOLOC_01740 3.75e-158 - - - S - - - Domain of unknown function (DUF3885)
KGMEOLOC_01741 4.15e-258 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KGMEOLOC_01742 1.65e-152 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
KGMEOLOC_01743 9.28e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
KGMEOLOC_01744 7.75e-126 yvgO - - - - - - -
KGMEOLOC_01746 0.0 yobO - - M - - - Pectate lyase superfamily protein
KGMEOLOC_01747 1.49e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
KGMEOLOC_01748 9.79e-192 yndL - - S - - - Replication protein
KGMEOLOC_01749 1.74e-11 - - - - - - - -
KGMEOLOC_01750 1.08e-172 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
KGMEOLOC_01751 2.25e-95 yndM - - S - - - Protein of unknown function (DUF2512)
KGMEOLOC_01753 1.35e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KGMEOLOC_01754 1.01e-67 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
KGMEOLOC_01755 5.22e-145 yneB - - L - - - resolvase
KGMEOLOC_01756 2.33e-43 ynzC - - S - - - UPF0291 protein
KGMEOLOC_01757 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KGMEOLOC_01758 1.08e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
KGMEOLOC_01759 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
KGMEOLOC_01760 1.28e-32 ynzD - - S - - - Spo0E like sporulation regulatory protein
KGMEOLOC_01761 3.14e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
KGMEOLOC_01762 2.47e-76 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
KGMEOLOC_01763 2.27e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
KGMEOLOC_01764 1.18e-98 yneK - - S - - - Protein of unknown function (DUF2621)
KGMEOLOC_01765 1.04e-83 cotM - - O ko:K06335 - ko00000 Spore coat protein
KGMEOLOC_01766 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
KGMEOLOC_01767 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
KGMEOLOC_01768 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KGMEOLOC_01769 9.94e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KGMEOLOC_01771 1.48e-45 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
KGMEOLOC_01772 1.24e-98 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
KGMEOLOC_01773 4.68e-71 yneQ - - - - - - -
KGMEOLOC_01774 2.67e-66 yneR - - S - - - Belongs to the HesB IscA family
KGMEOLOC_01775 9.09e-121 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KGMEOLOC_01776 9.94e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
KGMEOLOC_01777 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KGMEOLOC_01778 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KGMEOLOC_01779 3.81e-20 - - - - - - - -
KGMEOLOC_01780 1.82e-63 ynfC - - - - - - -
KGMEOLOC_01781 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
KGMEOLOC_01782 2.82e-234 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
KGMEOLOC_01783 2.88e-249 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
KGMEOLOC_01784 1.84e-147 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
KGMEOLOC_01785 1.23e-274 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
KGMEOLOC_01786 2.71e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KGMEOLOC_01787 1.57e-234 regR - - K ko:K02525 - ko00000,ko03000 transcriptional
KGMEOLOC_01788 2.27e-288 exuT - - G ko:K08191,ko:K08194 - ko00000,ko02000 Sugar (and other) transporter
KGMEOLOC_01789 1.59e-205 yndG - - S - - - DoxX-like family
KGMEOLOC_01790 2.4e-52 - - - S - - - Domain of unknown function (DUF4166)
KGMEOLOC_01791 0.0 yndJ - - S - - - YndJ-like protein
KGMEOLOC_01793 3.74e-282 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
KGMEOLOC_01794 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
KGMEOLOC_01795 1.8e-70 yvlA - - S - - - Domain of unknown function (DUF4870)
KGMEOLOC_01796 8.94e-317 - - - T - - - Histidine kinase
KGMEOLOC_01797 1.61e-165 - - - T - - - Transcriptional regulatory protein, C terminal
KGMEOLOC_01798 0.0 ynfF 3.2.1.136 GH5 G ko:K15924 - ko00000,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
KGMEOLOC_01799 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
KGMEOLOC_01800 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGMEOLOC_01801 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGMEOLOC_01802 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGMEOLOC_01803 4.25e-291 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KGMEOLOC_01804 8.63e-180 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KGMEOLOC_01805 2.23e-157 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KGMEOLOC_01806 7.33e-161 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KGMEOLOC_01807 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
KGMEOLOC_01808 3.48e-289 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KGMEOLOC_01809 1.94e-247 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KGMEOLOC_01810 7.76e-169 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KGMEOLOC_01811 1.44e-275 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KGMEOLOC_01812 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
KGMEOLOC_01813 6.17e-191 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
KGMEOLOC_01814 5.53e-96 yngA - - S - - - membrane
KGMEOLOC_01815 1.93e-210 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KGMEOLOC_01816 5.33e-135 yngC - - S - - - SNARE associated Golgi protein
KGMEOLOC_01817 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KGMEOLOC_01818 7.4e-180 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
KGMEOLOC_01819 8.91e-217 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
KGMEOLOC_01820 5.55e-316 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
KGMEOLOC_01821 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KGMEOLOC_01822 6.51e-269 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
KGMEOLOC_01823 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
KGMEOLOC_01824 1.67e-85 yngL - - S - - - Protein of unknown function (DUF1360)
KGMEOLOC_01825 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
KGMEOLOC_01826 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGMEOLOC_01827 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGMEOLOC_01828 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGMEOLOC_01829 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGMEOLOC_01830 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGMEOLOC_01831 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGMEOLOC_01832 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGMEOLOC_01833 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGMEOLOC_01834 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
KGMEOLOC_01835 2.44e-242 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
KGMEOLOC_01836 3.69e-312 yoeA - - V - - - MATE efflux family protein
KGMEOLOC_01837 4.66e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
KGMEOLOC_01839 3.97e-125 - - - L - - - Integrase
KGMEOLOC_01840 6.69e-47 yoeD - - G - - - Helix-turn-helix domain
KGMEOLOC_01841 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
KGMEOLOC_01842 5.85e-257 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
KGMEOLOC_01843 3.29e-67 - - - K - - - Helix-turn-helix domain
KGMEOLOC_01844 1.36e-07 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KGMEOLOC_01845 5.44e-147 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
KGMEOLOC_01846 5.3e-241 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KGMEOLOC_01847 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KGMEOLOC_01848 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
KGMEOLOC_01849 7.8e-207 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
KGMEOLOC_01850 3.58e-262 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KGMEOLOC_01851 7.2e-183 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KGMEOLOC_01852 3.37e-81 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
KGMEOLOC_01853 1.5e-101 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
KGMEOLOC_01854 1.66e-61 - - - L - - - Transposase
KGMEOLOC_01855 4.49e-184 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KGMEOLOC_01856 6.26e-289 - - - K - - - helix_turn_helix, arabinose operon control protein
KGMEOLOC_01857 1.73e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
KGMEOLOC_01858 1.45e-57 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KGMEOLOC_01859 2.4e-182 yoxB - - - - - - -
KGMEOLOC_01860 1.81e-260 yoaB - - EGP - - - the major facilitator superfamily
KGMEOLOC_01861 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
KGMEOLOC_01862 3.78e-249 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KGMEOLOC_01863 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KGMEOLOC_01864 8.57e-22 yoaF - - - - - - -
KGMEOLOC_01866 2.41e-130 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KGMEOLOC_01867 1.45e-60 - - - - - - - -
KGMEOLOC_01868 1.7e-115 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
KGMEOLOC_01869 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KGMEOLOC_01870 3.67e-71 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
KGMEOLOC_01871 3.17e-174 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
KGMEOLOC_01872 4.57e-123 yobS - - K - - - Transcriptional regulator
KGMEOLOC_01873 2.41e-175 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KGMEOLOC_01874 6.35e-86 yobW - - - - - - -
KGMEOLOC_01875 7.69e-73 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
KGMEOLOC_01876 1.19e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KGMEOLOC_01877 1.33e-117 yozB - - S ko:K08976 - ko00000 membrane
KGMEOLOC_01878 6.89e-186 - - - J - - - Protein required for attachment to host cells
KGMEOLOC_01879 1.6e-123 yocC - - - - - - -
KGMEOLOC_01880 3.47e-243 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
KGMEOLOC_01882 5.08e-170 yocH - - M - - - COG1388 FOG LysM repeat
KGMEOLOC_01883 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
KGMEOLOC_01884 2.32e-144 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KGMEOLOC_01886 5.24e-78 yocK - - T - - - general stress protein
KGMEOLOC_01887 2.71e-13 yocL - - - - - - -
KGMEOLOC_01888 3.51e-13 yocN - - - - - - -
KGMEOLOC_01889 2.29e-116 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KGMEOLOC_01890 9.63e-60 yozN - - - - - - -
KGMEOLOC_01891 6.36e-50 yocN - - - - - - -
KGMEOLOC_01892 5.32e-75 yozO - - S - - - Bacterial PH domain
KGMEOLOC_01894 4.69e-43 yozC - - - - - - -
KGMEOLOC_01895 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KGMEOLOC_01896 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
KGMEOLOC_01897 3.49e-214 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
KGMEOLOC_01898 5.08e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KGMEOLOC_01899 2.26e-218 yocS - - S ko:K03453 - ko00000 -transporter
KGMEOLOC_01900 1.99e-183 - - - S - - - Metallo-beta-lactamase superfamily
KGMEOLOC_01901 7.41e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
KGMEOLOC_01902 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
KGMEOLOC_01903 0.0 yojO - - P - - - Von Willebrand factor
KGMEOLOC_01904 4.2e-209 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
KGMEOLOC_01905 9.26e-145 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KGMEOLOC_01906 5.22e-172 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
KGMEOLOC_01907 4.23e-288 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
KGMEOLOC_01908 1.64e-144 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KGMEOLOC_01910 2.76e-316 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
KGMEOLOC_01911 8.69e-195 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KGMEOLOC_01912 1.57e-162 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
KGMEOLOC_01913 8.09e-80 yojF - - S - - - Protein of unknown function (DUF1806)
KGMEOLOC_01914 1.05e-30 - - - - - - - -
KGMEOLOC_01915 1.03e-210 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
KGMEOLOC_01916 4.87e-106 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
KGMEOLOC_01918 2.59e-89 iolK - - S - - - tautomerase
KGMEOLOC_01919 2.74e-92 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
KGMEOLOC_01920 1.2e-74 yodB - - K - - - transcriptional
KGMEOLOC_01921 3.3e-139 yodC - - C - - - nitroreductase
KGMEOLOC_01922 4.37e-143 yahD - - S ko:K06999 - ko00000 Carboxylesterase
KGMEOLOC_01923 2.39e-225 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
KGMEOLOC_01924 1.97e-28 - - - S - - - Protein of unknown function (DUF3311)
KGMEOLOC_01925 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KGMEOLOC_01926 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
KGMEOLOC_01927 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KGMEOLOC_01928 7.8e-27 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
KGMEOLOC_01929 1.59e-127 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
KGMEOLOC_01930 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
KGMEOLOC_01931 3.16e-168 yodH - - Q - - - Methyltransferase
KGMEOLOC_01932 1.68e-50 yodI - - - - - - -
KGMEOLOC_01933 7.76e-193 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
KGMEOLOC_01934 1.82e-162 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
KGMEOLOC_01936 4.03e-73 yodL - - S - - - YodL-like
KGMEOLOC_01937 3.86e-136 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
KGMEOLOC_01938 9.77e-34 yozD - - S - - - YozD-like protein
KGMEOLOC_01940 1.9e-161 yodN - - - - - - -
KGMEOLOC_01941 2.45e-48 yozE - - S - - - Belongs to the UPF0346 family
KGMEOLOC_01942 8.43e-64 yokU - - S - - - YokU-like protein, putative antitoxin
KGMEOLOC_01943 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
KGMEOLOC_01944 1.31e-208 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
KGMEOLOC_01945 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
KGMEOLOC_01946 2.3e-160 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KGMEOLOC_01947 1.19e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KGMEOLOC_01948 1.76e-314 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KGMEOLOC_01950 7.24e-188 yiiD - - K ko:K06323 - ko00000 acetyltransferase
KGMEOLOC_01951 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
KGMEOLOC_01952 6.96e-64 cgeC - - - ko:K06321 - ko00000 -
KGMEOLOC_01953 9.32e-92 cgeA - - - ko:K06319 - ko00000 -
KGMEOLOC_01954 5.69e-234 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
KGMEOLOC_01955 2e-285 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
KGMEOLOC_01956 3.54e-95 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
KGMEOLOC_01960 1.49e-273 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
KGMEOLOC_01961 1.2e-115 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KGMEOLOC_01962 0.0 baeB 3.1.2.6 - P ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Rhodanese Homology Domain
KGMEOLOC_01963 8.27e-293 - 1.8.5.4 - S ko:K17218 ko00920,map00920 ko00000,ko00001,ko01000 Pyridine nucleotide-disulphide oxidoreductase
KGMEOLOC_01964 2.85e-128 - - - T - - - helix_turn_helix, Lux Regulon
KGMEOLOC_01965 2.69e-254 - 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KGMEOLOC_01966 1.55e-110 - - - S ko:K07090 - ko00000 response to heat
KGMEOLOC_01968 9.7e-133 yokK - - S - - - SMI1 / KNR4 family
KGMEOLOC_01969 1.34e-167 - - - S - - - A nuclease of the HNH/ENDO VII superfamily with conserved WHH
KGMEOLOC_01970 0.0 yokA - - L - - - Recombinase
KGMEOLOC_01971 1.02e-135 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
KGMEOLOC_01972 4.61e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
KGMEOLOC_01973 1.2e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KGMEOLOC_01974 8.22e-90 ypoP - - K - - - transcriptional
KGMEOLOC_01975 4.79e-127 ypmS - - S - - - protein conserved in bacteria
KGMEOLOC_01976 2.58e-176 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
KGMEOLOC_01977 4.04e-149 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KGMEOLOC_01978 8.98e-55 ypmP - - S - - - Protein of unknown function (DUF2535)
KGMEOLOC_01979 4.25e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KGMEOLOC_01980 1.97e-231 yplP - - K - - - Transcriptional regulator
KGMEOLOC_01981 3.69e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
KGMEOLOC_01982 1.71e-150 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KGMEOLOC_01983 5.2e-118 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KGMEOLOC_01984 6.22e-204 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KGMEOLOC_01985 6.48e-148 ypjP - - S - - - YpjP-like protein
KGMEOLOC_01986 3.12e-175 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
KGMEOLOC_01987 4.8e-99 yphP - - S - - - Belongs to the UPF0403 family
KGMEOLOC_01988 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
KGMEOLOC_01989 2.1e-206 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
KGMEOLOC_01990 5.04e-132 yagB - - S ko:K06950 - ko00000 phosphohydrolase
KGMEOLOC_01991 2.67e-116 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
KGMEOLOC_01992 2.3e-227 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KGMEOLOC_01993 1.56e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
KGMEOLOC_01994 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
KGMEOLOC_01996 7.93e-50 - - - S - - - Protein of unknown function (DUF2564)
KGMEOLOC_01997 6.59e-40 ypeQ - - S - - - Zinc-finger
KGMEOLOC_01998 3.56e-160 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
KGMEOLOC_01999 2.79e-154 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KGMEOLOC_02000 7.37e-90 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
KGMEOLOC_02002 8.18e-211 ypcP - - L - - - 5'3' exonuclease
KGMEOLOC_02003 2.44e-10 - - - - - - - -
KGMEOLOC_02004 7.03e-53 ypbS - - S - - - Protein of unknown function (DUF2533)
KGMEOLOC_02005 0.0 ypbR - - S - - - Dynamin family
KGMEOLOC_02006 1.26e-117 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
KGMEOLOC_02007 6.51e-271 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
KGMEOLOC_02008 3.46e-143 - - - J - - - Acetyltransferase (GNAT) domain
KGMEOLOC_02009 3.81e-67 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
KGMEOLOC_02010 2.17e-12 - - - S - - - Bacillus cereus group antimicrobial protein
KGMEOLOC_02011 2.34e-128 ydfR - - S - - - Protein of unknown function (DUF421)
KGMEOLOC_02012 1.32e-131 yrdC - - Q - - - Isochorismatase family
KGMEOLOC_02013 1.78e-06 - - - S - - - Bacillus cereus group antimicrobial protein
KGMEOLOC_02014 1.77e-298 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
KGMEOLOC_02015 2e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KGMEOLOC_02016 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KGMEOLOC_02017 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
KGMEOLOC_02019 6.91e-31 - - - S - - - YpzG-like protein
KGMEOLOC_02020 7.1e-102 yqgA - - - - - - -
KGMEOLOC_02021 4.86e-281 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
KGMEOLOC_02022 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KGMEOLOC_02023 3.27e-129 ypsA - - S - - - Belongs to the UPF0398 family
KGMEOLOC_02024 9.36e-48 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
KGMEOLOC_02026 1.99e-302 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
KGMEOLOC_02027 5.39e-278 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KGMEOLOC_02028 2.17e-199 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KGMEOLOC_02029 1.21e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
KGMEOLOC_02030 9.14e-96 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KGMEOLOC_02031 3.1e-86 yppG - - S - - - YppG-like protein
KGMEOLOC_02035 0.000542 - - - - ko:K06430 - ko00000 -
KGMEOLOC_02036 1.88e-185 yppC - - S - - - Protein of unknown function (DUF2515)
KGMEOLOC_02037 8.84e-146 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KGMEOLOC_02038 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KGMEOLOC_02039 4.43e-120 ypoC - - - - - - -
KGMEOLOC_02040 1.02e-157 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KGMEOLOC_02041 3.42e-167 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
KGMEOLOC_02042 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
KGMEOLOC_02043 1.78e-284 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
KGMEOLOC_02044 2.03e-106 ypmB - - S - - - protein conserved in bacteria
KGMEOLOC_02045 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
KGMEOLOC_02046 2.37e-177 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
KGMEOLOC_02047 4.69e-131 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
KGMEOLOC_02048 1.06e-292 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
KGMEOLOC_02049 2.41e-84 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KGMEOLOC_02050 3.44e-203 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KGMEOLOC_02051 3.42e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
KGMEOLOC_02052 9.42e-232 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KGMEOLOC_02053 2.16e-282 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KGMEOLOC_02054 1.87e-271 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
KGMEOLOC_02055 1.56e-170 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
KGMEOLOC_02056 6.19e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
KGMEOLOC_02057 9.78e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KGMEOLOC_02058 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
KGMEOLOC_02059 4.31e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KGMEOLOC_02060 3.63e-292 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
KGMEOLOC_02061 2.05e-182 ypjB - - S - - - sporulation protein
KGMEOLOC_02062 9.19e-137 ypjA - - S - - - membrane
KGMEOLOC_02063 4.44e-151 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
KGMEOLOC_02064 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
KGMEOLOC_02065 2.86e-127 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
KGMEOLOC_02066 9.97e-103 ypiF - - S - - - Protein of unknown function (DUF2487)
KGMEOLOC_02067 2.6e-129 ypiB - - S - - - Belongs to the UPF0302 family
KGMEOLOC_02068 6.42e-300 ypiA - - S - - - COG0457 FOG TPR repeat
KGMEOLOC_02069 7.29e-304 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KGMEOLOC_02070 5.29e-262 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
KGMEOLOC_02071 9.08e-259 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KGMEOLOC_02072 1.97e-187 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KGMEOLOC_02073 3.12e-293 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KGMEOLOC_02074 3.43e-155 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
KGMEOLOC_02075 2.11e-170 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
KGMEOLOC_02076 6.09e-214 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KGMEOLOC_02077 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KGMEOLOC_02078 2.93e-79 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
KGMEOLOC_02079 4.7e-262 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KGMEOLOC_02080 9.75e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KGMEOLOC_02081 3.47e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
KGMEOLOC_02082 1.47e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KGMEOLOC_02083 2.29e-251 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KGMEOLOC_02084 7.76e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KGMEOLOC_02085 3.43e-40 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
KGMEOLOC_02086 1.55e-121 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
KGMEOLOC_02087 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
KGMEOLOC_02088 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
KGMEOLOC_02089 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KGMEOLOC_02090 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KGMEOLOC_02091 5.23e-105 yphF - - - - - - -
KGMEOLOC_02092 3.25e-23 yphE - - S - - - Protein of unknown function (DUF2768)
KGMEOLOC_02093 4.93e-244 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
KGMEOLOC_02094 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
KGMEOLOC_02095 6.19e-136 yphA - - - - - - -
KGMEOLOC_02096 1.87e-12 - - - S - - - YpzI-like protein
KGMEOLOC_02097 6.18e-240 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KGMEOLOC_02098 5.73e-264 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
KGMEOLOC_02099 4.97e-147 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
KGMEOLOC_02100 7.86e-18 - - - S - - - Family of unknown function (DUF5359)
KGMEOLOC_02101 6.52e-05 ypfA - - M - - - type IV pilus assembly PilZ
KGMEOLOC_02102 8.8e-33 ypfA - - M - - - Flagellar protein YcgR
KGMEOLOC_02103 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
KGMEOLOC_02104 4.58e-214 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
KGMEOLOC_02105 1.11e-156 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
KGMEOLOC_02106 1.85e-239 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
KGMEOLOC_02107 1.81e-311 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KGMEOLOC_02108 4.07e-138 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KGMEOLOC_02109 1.4e-190 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
KGMEOLOC_02110 6.69e-112 ypbF - - S - - - Protein of unknown function (DUF2663)
KGMEOLOC_02111 2.1e-139 ypbE - - M - - - Lysin motif
KGMEOLOC_02112 1.09e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
KGMEOLOC_02113 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
KGMEOLOC_02114 1.14e-257 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
KGMEOLOC_02115 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
KGMEOLOC_02116 1.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KGMEOLOC_02117 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KGMEOLOC_02118 1.02e-256 rsiX - - - - - - -
KGMEOLOC_02119 1.77e-110 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KGMEOLOC_02120 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KGMEOLOC_02121 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGMEOLOC_02122 6.24e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
KGMEOLOC_02123 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
KGMEOLOC_02124 2.23e-126 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
KGMEOLOC_02125 7.38e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KGMEOLOC_02126 8.99e-116 spmB - - S ko:K06374 - ko00000 Spore maturation protein
KGMEOLOC_02127 3.75e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
KGMEOLOC_02128 1.14e-275 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KGMEOLOC_02129 1.51e-122 ypuI - - S - - - Protein of unknown function (DUF3907)
KGMEOLOC_02130 2.73e-133 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KGMEOLOC_02131 2.09e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KGMEOLOC_02133 1.99e-121 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
KGMEOLOC_02134 2.74e-84 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KGMEOLOC_02135 6.92e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KGMEOLOC_02136 1.8e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KGMEOLOC_02137 9.75e-145 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
KGMEOLOC_02138 2.76e-270 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KGMEOLOC_02139 4.92e-71 ypuD - - - - - - -
KGMEOLOC_02140 6.56e-131 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KGMEOLOC_02141 1.42e-107 ccdC1 - - O - - - Protein of unknown function (DUF1453)
KGMEOLOC_02142 4.12e-104 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KGMEOLOC_02143 5.04e-203 ypuA - - S - - - Secreted protein
KGMEOLOC_02144 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KGMEOLOC_02145 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
KGMEOLOC_02146 1.31e-142 - - - S ko:K06407 - ko00000 stage V sporulation protein
KGMEOLOC_02147 1.51e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
KGMEOLOC_02148 5.77e-244 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
KGMEOLOC_02149 9.92e-104 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
KGMEOLOC_02150 1.01e-78 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
KGMEOLOC_02151 4.7e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
KGMEOLOC_02152 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KGMEOLOC_02153 2.36e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
KGMEOLOC_02154 4.86e-77 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
KGMEOLOC_02155 6.08e-274 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KGMEOLOC_02156 1.1e-192 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KGMEOLOC_02157 4.26e-295 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
KGMEOLOC_02158 7.9e-214 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
KGMEOLOC_02159 9.51e-51 - - - S - - - Protein of unknown function (DUF4227)
KGMEOLOC_02160 4.56e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
KGMEOLOC_02161 3.53e-142 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
KGMEOLOC_02163 4.38e-47 yqkK - - - - - - -
KGMEOLOC_02164 1.96e-30 - - - - - - - -
KGMEOLOC_02165 4.12e-310 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
KGMEOLOC_02166 3.55e-316 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
KGMEOLOC_02167 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
KGMEOLOC_02168 1.75e-95 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
KGMEOLOC_02169 2.04e-81 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
KGMEOLOC_02170 8.39e-78 ansR - - K - - - Transcriptional regulator
KGMEOLOC_02171 6.7e-286 yqxK - - L - - - DNA helicase
KGMEOLOC_02172 1.04e-122 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
KGMEOLOC_02173 2.01e-10 - - - S - - - Protein of unknown function (DUF3936)
KGMEOLOC_02174 2.27e-218 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
KGMEOLOC_02175 1.45e-11 yqkE - - S - - - Protein of unknown function (DUF3886)
KGMEOLOC_02176 1.05e-228 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
KGMEOLOC_02177 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
KGMEOLOC_02178 9.32e-81 yqkB - - S - - - Belongs to the HesB IscA family
KGMEOLOC_02179 5.45e-231 yqkA - - K - - - GrpB protein
KGMEOLOC_02180 5.96e-81 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
KGMEOLOC_02181 2.81e-115 yqjY - - K ko:K06977 - ko00000 acetyltransferase
KGMEOLOC_02182 1.7e-301 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KGMEOLOC_02183 3.89e-77 - - - S - - - YolD-like protein
KGMEOLOC_02185 1.11e-243 yueF - - S - - - transporter activity
KGMEOLOC_02187 2.67e-96 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KGMEOLOC_02188 6.33e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
KGMEOLOC_02189 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
KGMEOLOC_02190 1.29e-184 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KGMEOLOC_02191 7.17e-167 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KGMEOLOC_02192 1.26e-45 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KGMEOLOC_02193 2.88e-187 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KGMEOLOC_02194 2.05e-176 - - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
KGMEOLOC_02195 1.17e-307 - 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
KGMEOLOC_02196 5.93e-283 - 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KGMEOLOC_02197 0.0 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KGMEOLOC_02198 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KGMEOLOC_02199 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KGMEOLOC_02200 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KGMEOLOC_02201 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KGMEOLOC_02202 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KGMEOLOC_02203 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KGMEOLOC_02204 4.81e-169 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
KGMEOLOC_02205 1.3e-270 - 6.1.3.1, 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508,ko:K22319 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KGMEOLOC_02206 3.24e-31 - 6.1.3.1, 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508,ko:K22319 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KGMEOLOC_02209 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KGMEOLOC_02210 5.26e-123 nusG1 - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
KGMEOLOC_02211 1.36e-212 - - - K - - - LysR substrate binding domain
KGMEOLOC_02212 5.5e-67 - - - S - - - GlpM protein
KGMEOLOC_02213 1.27e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KGMEOLOC_02214 2.72e-190 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KGMEOLOC_02215 1.18e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KGMEOLOC_02216 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KGMEOLOC_02217 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KGMEOLOC_02218 1.16e-302 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KGMEOLOC_02219 1.3e-34 yqzJ - - - - - - -
KGMEOLOC_02220 1.01e-191 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KGMEOLOC_02221 1.06e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
KGMEOLOC_02222 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KGMEOLOC_02223 9.74e-98 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
KGMEOLOC_02225 5.47e-125 yqjB - - S - - - protein conserved in bacteria
KGMEOLOC_02226 1.6e-219 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
KGMEOLOC_02227 2.58e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KGMEOLOC_02228 1.04e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
KGMEOLOC_02229 5.83e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KGMEOLOC_02230 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
KGMEOLOC_02231 1.48e-219 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KGMEOLOC_02232 7.91e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KGMEOLOC_02233 1.7e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KGMEOLOC_02234 8.24e-224 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KGMEOLOC_02235 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KGMEOLOC_02236 1.2e-263 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
KGMEOLOC_02237 1.58e-261 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KGMEOLOC_02238 2.03e-196 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
KGMEOLOC_02239 0.0 bkdR - - KT - - - Transcriptional regulator
KGMEOLOC_02240 6.25e-47 yqzF - - S - - - Protein of unknown function (DUF2627)
KGMEOLOC_02241 6.92e-206 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KGMEOLOC_02242 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
KGMEOLOC_02243 1.85e-265 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
KGMEOLOC_02244 1.93e-264 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
KGMEOLOC_02245 3.72e-201 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
KGMEOLOC_02246 1.38e-272 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
KGMEOLOC_02247 1.9e-175 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
KGMEOLOC_02248 1.69e-137 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
KGMEOLOC_02250 1.96e-131 - - - P - - - Probably functions as a manganese efflux pump
KGMEOLOC_02251 6.93e-147 - - - K - - - Protein of unknown function (DUF1232)
KGMEOLOC_02253 3.37e-274 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KGMEOLOC_02256 5.23e-277 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KGMEOLOC_02257 6.11e-187 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
KGMEOLOC_02258 3.22e-306 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
KGMEOLOC_02259 2.45e-227 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
KGMEOLOC_02260 7.46e-158 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
KGMEOLOC_02261 4.38e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
KGMEOLOC_02262 2.51e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
KGMEOLOC_02263 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KGMEOLOC_02264 8.13e-207 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KGMEOLOC_02265 2.67e-52 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KGMEOLOC_02266 6.82e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KGMEOLOC_02267 3.05e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KGMEOLOC_02268 2.2e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KGMEOLOC_02269 1.93e-87 yqhY - - S - - - protein conserved in bacteria
KGMEOLOC_02270 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KGMEOLOC_02271 2.32e-86 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KGMEOLOC_02272 2.74e-94 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
KGMEOLOC_02273 3.48e-150 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
KGMEOLOC_02274 1.05e-130 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
KGMEOLOC_02275 5.23e-261 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
KGMEOLOC_02276 3.72e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
KGMEOLOC_02277 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
KGMEOLOC_02278 5.93e-113 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
KGMEOLOC_02279 5.39e-222 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
KGMEOLOC_02280 9.89e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
KGMEOLOC_02281 6.82e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KGMEOLOC_02282 1.27e-250 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
KGMEOLOC_02283 3.99e-118 yqhR - - S - - - Conserved membrane protein YqhR
KGMEOLOC_02284 7.33e-221 yqhQ - - S - - - Protein of unknown function (DUF1385)
KGMEOLOC_02285 7.65e-83 yqhP - - - - - - -
KGMEOLOC_02286 7e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
KGMEOLOC_02287 5.64e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
KGMEOLOC_02288 1.54e-174 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KGMEOLOC_02289 1.52e-16 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KGMEOLOC_02290 3.18e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
KGMEOLOC_02291 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KGMEOLOC_02292 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KGMEOLOC_02293 2.44e-266 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
KGMEOLOC_02294 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
KGMEOLOC_02295 1.11e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
KGMEOLOC_02296 2.31e-32 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
KGMEOLOC_02297 2.75e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
KGMEOLOC_02298 1.82e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
KGMEOLOC_02299 3.27e-103 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
KGMEOLOC_02300 5.91e-159 yqxM - - - ko:K19433 - ko00000 -
KGMEOLOC_02301 1.69e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
KGMEOLOC_02302 2e-36 yqzE - - S - - - YqzE-like protein
KGMEOLOC_02303 1.2e-83 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
KGMEOLOC_02304 9.51e-90 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
KGMEOLOC_02305 6.31e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
KGMEOLOC_02306 2.37e-95 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
KGMEOLOC_02307 4.46e-66 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
KGMEOLOC_02308 2.62e-239 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
KGMEOLOC_02309 1.34e-258 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KGMEOLOC_02310 4.53e-239 yqxL - - P - - - Mg2 transporter protein
KGMEOLOC_02311 6.5e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
KGMEOLOC_02312 1.5e-192 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KGMEOLOC_02314 1.15e-86 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
KGMEOLOC_02315 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
KGMEOLOC_02316 5.96e-158 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
KGMEOLOC_02317 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
KGMEOLOC_02318 2.99e-65 dglA - - S - - - Thiamine-binding protein
KGMEOLOC_02319 2.13e-97 yqgU - - - - - - -
KGMEOLOC_02320 3.78e-146 yqgU - - - - - - -
KGMEOLOC_02321 1.3e-286 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
KGMEOLOC_02322 1.23e-229 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
KGMEOLOC_02323 9.1e-39 yqgQ - - S - - - Protein conserved in bacteria
KGMEOLOC_02324 3.9e-303 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
KGMEOLOC_02325 5.38e-11 yqgO - - - - - - -
KGMEOLOC_02326 8e-131 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KGMEOLOC_02327 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KGMEOLOC_02328 3.42e-68 yqzD - - - - - - -
KGMEOLOC_02329 2.5e-99 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KGMEOLOC_02330 9.44e-188 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KGMEOLOC_02331 4.3e-188 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KGMEOLOC_02332 1.02e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
KGMEOLOC_02333 6.1e-204 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
KGMEOLOC_02334 9.5e-208 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
KGMEOLOC_02335 1.55e-72 - - - L - - - COG2963 Transposase and inactivated derivatives
KGMEOLOC_02336 1.13e-149 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
KGMEOLOC_02337 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
KGMEOLOC_02338 2.37e-289 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
KGMEOLOC_02339 4.22e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
KGMEOLOC_02340 4.77e-100 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
KGMEOLOC_02341 7.3e-168 yqgB - - S - - - Protein of unknown function (DUF1189)
KGMEOLOC_02342 1.84e-64 yqfZ - - M ko:K06417 - ko00000 LysM domain
KGMEOLOC_02343 1.97e-256 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KGMEOLOC_02344 3.34e-80 yqfX - - S - - - membrane
KGMEOLOC_02345 7.06e-143 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
KGMEOLOC_02346 2.25e-100 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
KGMEOLOC_02347 5.44e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KGMEOLOC_02348 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
KGMEOLOC_02349 4.23e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KGMEOLOC_02350 1.2e-314 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KGMEOLOC_02351 4.16e-89 yqfQ - - S - - - YqfQ-like protein
KGMEOLOC_02352 8.66e-227 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KGMEOLOC_02353 7.93e-271 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KGMEOLOC_02354 2.97e-162 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
KGMEOLOC_02355 9.68e-83 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
KGMEOLOC_02356 3.97e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KGMEOLOC_02357 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KGMEOLOC_02358 3.33e-113 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
KGMEOLOC_02359 5.46e-192 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KGMEOLOC_02360 5.89e-145 ccpN - - K - - - CBS domain
KGMEOLOC_02361 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
KGMEOLOC_02362 5.19e-223 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
KGMEOLOC_02363 2.14e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
KGMEOLOC_02364 6e-24 - - - S - - - YqzL-like protein
KGMEOLOC_02365 1.42e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KGMEOLOC_02366 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KGMEOLOC_02367 6.41e-84 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
KGMEOLOC_02368 7.14e-105 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KGMEOLOC_02369 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
KGMEOLOC_02370 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
KGMEOLOC_02371 8.17e-286 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
KGMEOLOC_02372 3.57e-61 yqfC - - S - - - sporulation protein YqfC
KGMEOLOC_02373 7.93e-89 yqfB - - - - - - -
KGMEOLOC_02374 4.48e-189 yqfA - - S - - - UPF0365 protein
KGMEOLOC_02375 3.28e-296 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
KGMEOLOC_02376 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
KGMEOLOC_02377 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
KGMEOLOC_02378 8.3e-203 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
KGMEOLOC_02379 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
KGMEOLOC_02380 1.75e-181 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KGMEOLOC_02381 6.58e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
KGMEOLOC_02382 4.93e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KGMEOLOC_02383 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
KGMEOLOC_02384 5.18e-110 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KGMEOLOC_02385 5.74e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KGMEOLOC_02386 2.04e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
KGMEOLOC_02387 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KGMEOLOC_02388 2.1e-71 yqxA - - S - - - Protein of unknown function (DUF3679)
KGMEOLOC_02389 9.09e-280 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
KGMEOLOC_02390 2.51e-260 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KGMEOLOC_02391 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
KGMEOLOC_02392 3.84e-234 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
KGMEOLOC_02393 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
KGMEOLOC_02394 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
KGMEOLOC_02395 1.51e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
KGMEOLOC_02396 1.19e-192 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KGMEOLOC_02397 1.02e-179 yqeM - - Q - - - Methyltransferase
KGMEOLOC_02398 4.65e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KGMEOLOC_02399 1.68e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
KGMEOLOC_02400 7.09e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KGMEOLOC_02401 3.12e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
KGMEOLOC_02402 2.52e-202 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KGMEOLOC_02403 1.17e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KGMEOLOC_02404 5.51e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
KGMEOLOC_02406 1.85e-180 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
KGMEOLOC_02407 1.2e-182 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
KGMEOLOC_02408 2.92e-138 yqeD - - S - - - SNARE associated Golgi protein
KGMEOLOC_02409 1.68e-18 - 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
KGMEOLOC_02410 4.18e-282 - - - EGP - - - Transmembrane secretion effector
KGMEOLOC_02411 5.58e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KGMEOLOC_02412 1.72e-209 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
KGMEOLOC_02413 6.92e-123 - - - K - - - Transcriptional regulator PadR-like family
KGMEOLOC_02414 1.84e-91 psiE - - S ko:K13256 - ko00000 Belongs to the PsiE family
KGMEOLOC_02415 2.67e-308 yrkQ - - T - - - Histidine kinase
KGMEOLOC_02416 2.5e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
KGMEOLOC_02418 7.53e-283 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
KGMEOLOC_02419 3.27e-134 yrkN - - K - - - Acetyltransferase (GNAT) family
KGMEOLOC_02420 1.63e-131 yqaC - - F - - - adenylate kinase activity
KGMEOLOC_02421 3.54e-113 - - - K - - - acetyltransferase
KGMEOLOC_02422 1.42e-122 - - - S - - - DinB family
KGMEOLOC_02424 3.71e-193 supH - - S - - - hydrolase
KGMEOLOC_02425 3.29e-193 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
KGMEOLOC_02426 1.23e-169 - - - K - - - Helix-turn-helix domain, rpiR family
KGMEOLOC_02427 4.54e-243 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KGMEOLOC_02428 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KGMEOLOC_02429 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
KGMEOLOC_02430 2.06e-234 romA - - S - - - Beta-lactamase superfamily domain
KGMEOLOC_02431 1.96e-108 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KGMEOLOC_02432 1.94e-213 yybE - - K - - - Transcriptional regulator
KGMEOLOC_02433 7.81e-268 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KGMEOLOC_02434 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
KGMEOLOC_02435 3.36e-130 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
KGMEOLOC_02436 1.33e-122 yrhH - - Q - - - methyltransferase
KGMEOLOC_02437 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
KGMEOLOC_02438 3.96e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
KGMEOLOC_02439 1.54e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
KGMEOLOC_02440 5.52e-184 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
KGMEOLOC_02441 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
KGMEOLOC_02442 4.76e-106 yrhD - - S - - - Protein of unknown function (DUF1641)
KGMEOLOC_02443 3.31e-47 yrhC - - S - - - YrhC-like protein
KGMEOLOC_02444 1.17e-271 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KGMEOLOC_02445 7.96e-219 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
KGMEOLOC_02446 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KGMEOLOC_02447 7.23e-155 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
KGMEOLOC_02448 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
KGMEOLOC_02449 1.85e-126 yrrS - - S - - - Protein of unknown function (DUF1510)
KGMEOLOC_02450 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
KGMEOLOC_02451 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KGMEOLOC_02452 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
KGMEOLOC_02453 1.88e-312 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
KGMEOLOC_02454 1.33e-223 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
KGMEOLOC_02455 4.01e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
KGMEOLOC_02456 2.82e-259 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KGMEOLOC_02457 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
KGMEOLOC_02458 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KGMEOLOC_02459 1.1e-55 yrzL - - S - - - Belongs to the UPF0297 family
KGMEOLOC_02460 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KGMEOLOC_02461 2.82e-238 yrrI - - S - - - AI-2E family transporter
KGMEOLOC_02462 2.8e-171 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KGMEOLOC_02463 1.56e-189 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KGMEOLOC_02464 2.38e-141 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KGMEOLOC_02465 7.94e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KGMEOLOC_02466 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
KGMEOLOC_02467 8.4e-42 yrzR - - - - - - -
KGMEOLOC_02468 1.76e-107 yrrD - - S - - - protein conserved in bacteria
KGMEOLOC_02469 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KGMEOLOC_02470 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
KGMEOLOC_02471 3.55e-282 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KGMEOLOC_02472 2.56e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
KGMEOLOC_02473 9.19e-84 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
KGMEOLOC_02474 1.85e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KGMEOLOC_02475 1.18e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
KGMEOLOC_02476 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KGMEOLOC_02477 7.37e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
KGMEOLOC_02480 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
KGMEOLOC_02481 3.48e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KGMEOLOC_02482 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KGMEOLOC_02483 5.1e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KGMEOLOC_02484 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
KGMEOLOC_02485 4.68e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
KGMEOLOC_02486 2.65e-113 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
KGMEOLOC_02487 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KGMEOLOC_02488 3.45e-68 yrzD - - S - - - Post-transcriptional regulator
KGMEOLOC_02489 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KGMEOLOC_02490 2.03e-143 yrbG - - S - - - membrane
KGMEOLOC_02491 9.08e-81 yrzE - - S - - - Protein of unknown function (DUF3792)
KGMEOLOC_02492 1.78e-51 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
KGMEOLOC_02493 2.01e-293 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KGMEOLOC_02494 4.96e-247 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KGMEOLOC_02495 1.39e-28 yrzS - - S - - - Protein of unknown function (DUF2905)
KGMEOLOC_02496 6.17e-237 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KGMEOLOC_02497 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KGMEOLOC_02498 1.03e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
KGMEOLOC_02500 8.92e-61 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KGMEOLOC_02501 2.6e-263 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
KGMEOLOC_02502 1.04e-272 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KGMEOLOC_02503 9.86e-201 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
KGMEOLOC_02504 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
KGMEOLOC_02505 5.11e-288 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
KGMEOLOC_02506 3.02e-124 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
KGMEOLOC_02507 8.16e-206 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
KGMEOLOC_02508 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
KGMEOLOC_02509 7.1e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KGMEOLOC_02510 3.64e-140 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
KGMEOLOC_02511 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
KGMEOLOC_02512 1.42e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
KGMEOLOC_02513 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
KGMEOLOC_02514 3.59e-206 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
KGMEOLOC_02515 4.75e-39 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
KGMEOLOC_02516 4.82e-133 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
KGMEOLOC_02517 3.94e-184 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
KGMEOLOC_02518 1.68e-155 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KGMEOLOC_02519 6.14e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
KGMEOLOC_02520 4.34e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
KGMEOLOC_02521 1.06e-234 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
KGMEOLOC_02522 2.5e-164 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
KGMEOLOC_02523 1e-131 maf - - D ko:K06287 - ko00000 septum formation protein Maf
KGMEOLOC_02524 2.67e-210 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
KGMEOLOC_02525 1.27e-171 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
KGMEOLOC_02526 2.04e-311 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
KGMEOLOC_02527 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KGMEOLOC_02528 1.53e-35 - - - - - - - -
KGMEOLOC_02529 1.89e-251 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KGMEOLOC_02530 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
KGMEOLOC_02531 1.62e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
KGMEOLOC_02532 1.2e-236 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
KGMEOLOC_02533 9.78e-185 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
KGMEOLOC_02534 4.44e-224 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KGMEOLOC_02535 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
KGMEOLOC_02536 9.08e-317 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KGMEOLOC_02537 8.26e-116 ysxD - - - - - - -
KGMEOLOC_02538 3.1e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
KGMEOLOC_02539 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KGMEOLOC_02540 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
KGMEOLOC_02541 3.28e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KGMEOLOC_02542 2.18e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KGMEOLOC_02543 2.34e-241 ysoA - - H - - - Tetratricopeptide repeat
KGMEOLOC_02544 3.77e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KGMEOLOC_02545 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KGMEOLOC_02546 3.68e-256 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KGMEOLOC_02547 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KGMEOLOC_02548 6.75e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KGMEOLOC_02549 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
KGMEOLOC_02550 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
KGMEOLOC_02555 1.21e-120 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
KGMEOLOC_02556 1.59e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KGMEOLOC_02557 1.44e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KGMEOLOC_02558 7.73e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
KGMEOLOC_02559 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KGMEOLOC_02560 3.77e-97 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
KGMEOLOC_02561 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
KGMEOLOC_02562 2.67e-101 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
KGMEOLOC_02563 4.34e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
KGMEOLOC_02564 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
KGMEOLOC_02565 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
KGMEOLOC_02566 6.01e-104 yslB - - S - - - Protein of unknown function (DUF2507)
KGMEOLOC_02567 1.49e-275 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KGMEOLOC_02568 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KGMEOLOC_02569 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
KGMEOLOC_02570 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
KGMEOLOC_02571 5.22e-229 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
KGMEOLOC_02572 8.64e-178 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
KGMEOLOC_02573 7.4e-180 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
KGMEOLOC_02574 6.22e-134 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
KGMEOLOC_02575 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KGMEOLOC_02576 1.77e-165 ywbB - - S - - - Protein of unknown function (DUF2711)
KGMEOLOC_02577 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
KGMEOLOC_02578 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KGMEOLOC_02579 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
KGMEOLOC_02580 6.04e-109 yshB - - S - - - membrane protein, required for colicin V production
KGMEOLOC_02581 1.47e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KGMEOLOC_02582 7.57e-216 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KGMEOLOC_02583 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KGMEOLOC_02584 2.19e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KGMEOLOC_02585 4.63e-173 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KGMEOLOC_02586 1.07e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
KGMEOLOC_02587 4.53e-264 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
KGMEOLOC_02588 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
KGMEOLOC_02589 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
KGMEOLOC_02590 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
KGMEOLOC_02591 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
KGMEOLOC_02592 1.18e-191 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
KGMEOLOC_02593 4.38e-215 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
KGMEOLOC_02594 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
KGMEOLOC_02595 2.09e-288 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
KGMEOLOC_02596 1.85e-182 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
KGMEOLOC_02597 3.43e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
KGMEOLOC_02598 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
KGMEOLOC_02599 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
KGMEOLOC_02600 1.71e-241 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
KGMEOLOC_02601 1.85e-263 ysdC - - G - - - COG1363 Cellulase M and related proteins
KGMEOLOC_02602 9.71e-90 ysdB - - S - - - Sigma-w pathway protein YsdB
KGMEOLOC_02603 8.03e-58 ysdA - - S - - - Membrane
KGMEOLOC_02604 2.3e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KGMEOLOC_02605 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
KGMEOLOC_02606 1.79e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KGMEOLOC_02607 1.08e-147 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KGMEOLOC_02608 2.76e-69 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
KGMEOLOC_02609 1.05e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
KGMEOLOC_02610 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KGMEOLOC_02611 2.52e-194 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
KGMEOLOC_02612 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KGMEOLOC_02613 5.94e-199 ytxC - - S - - - YtxC-like family
KGMEOLOC_02614 4.64e-142 ytxB - - S - - - SNARE associated Golgi protein
KGMEOLOC_02615 1.42e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
KGMEOLOC_02616 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
KGMEOLOC_02617 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KGMEOLOC_02618 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KGMEOLOC_02619 1.09e-249 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KGMEOLOC_02620 1.69e-89 ytcD - - K - - - Transcriptional regulator
KGMEOLOC_02621 4.15e-261 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
KGMEOLOC_02622 1.93e-206 ytbE - - S - - - reductase
KGMEOLOC_02623 1.52e-130 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KGMEOLOC_02624 2e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
KGMEOLOC_02625 9.87e-203 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KGMEOLOC_02626 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KGMEOLOC_02627 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
KGMEOLOC_02628 2.9e-167 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGMEOLOC_02629 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
KGMEOLOC_02630 1.32e-308 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
KGMEOLOC_02631 1.42e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
KGMEOLOC_02632 2.33e-84 yjdF3 - - S - - - Protein of unknown function (DUF2992)
KGMEOLOC_02633 5.65e-96 ytwI - - S - - - membrane
KGMEOLOC_02634 9.96e-248 ytvI - - S - - - sporulation integral membrane protein YtvI
KGMEOLOC_02635 3.42e-84 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
KGMEOLOC_02636 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
KGMEOLOC_02637 3.98e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KGMEOLOC_02638 1.15e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KGMEOLOC_02639 1.53e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KGMEOLOC_02640 1.48e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
KGMEOLOC_02641 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
KGMEOLOC_02642 4.94e-75 ytrH - - S - - - Sporulation protein YtrH
KGMEOLOC_02643 2.64e-114 ytrI - - - - - - -
KGMEOLOC_02644 7.04e-32 - - - - - - - -
KGMEOLOC_02645 2.14e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
KGMEOLOC_02646 1.06e-63 ytpI - - S - - - YtpI-like protein
KGMEOLOC_02647 6.77e-305 ytoI - - K - - - transcriptional regulator containing CBS domains
KGMEOLOC_02648 4.16e-166 ytkL - - S - - - Belongs to the UPF0173 family
KGMEOLOC_02649 2.06e-184 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGMEOLOC_02651 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
KGMEOLOC_02652 3.03e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
KGMEOLOC_02653 4.03e-115 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
KGMEOLOC_02654 2.33e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KGMEOLOC_02655 7.8e-237 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
KGMEOLOC_02656 1.36e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KGMEOLOC_02657 4.77e-100 ytfJ - - S - - - Sporulation protein YtfJ
KGMEOLOC_02658 3.82e-158 ytfI - - S - - - Protein of unknown function (DUF2953)
KGMEOLOC_02659 2.77e-114 yteJ - - S - - - RDD family
KGMEOLOC_02660 2.23e-235 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
KGMEOLOC_02661 8.09e-197 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KGMEOLOC_02662 0.0 ytcJ - - S - - - amidohydrolase
KGMEOLOC_02663 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KGMEOLOC_02664 2.05e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
KGMEOLOC_02665 1.75e-256 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KGMEOLOC_02666 1.42e-268 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
KGMEOLOC_02667 1.68e-309 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KGMEOLOC_02668 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KGMEOLOC_02669 1.85e-199 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
KGMEOLOC_02670 3.57e-143 yttP - - K - - - Transcriptional regulator
KGMEOLOC_02671 5.2e-113 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
KGMEOLOC_02672 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
KGMEOLOC_02673 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KGMEOLOC_02674 4.48e-312 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KGMEOLOC_02675 1.96e-136 yokH - - G - - - SMI1 / KNR4 family
KGMEOLOC_02677 6.45e-132 - - - - - - - -
KGMEOLOC_02679 7.51e-116 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
KGMEOLOC_02681 1.99e-39 - - - S - - - Phage-like element PBSX protein XtrA
KGMEOLOC_02682 2.93e-41 - - - - - - - -
KGMEOLOC_02683 1.4e-44 dnaC 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
KGMEOLOC_02684 9.55e-286 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KGMEOLOC_02686 1.65e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
KGMEOLOC_02688 1.29e-180 - - - E - - - GDSL-like Lipase/Acylhydrolase family
KGMEOLOC_02689 6.08e-194 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KGMEOLOC_02690 7.76e-191 - - - K - - - Transcriptional regulator
KGMEOLOC_02691 9.98e-161 ygaZ - - E - - - AzlC protein
KGMEOLOC_02692 3.06e-64 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
KGMEOLOC_02693 5.98e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KGMEOLOC_02694 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KGMEOLOC_02695 2.96e-157 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
KGMEOLOC_02696 5.07e-151 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
KGMEOLOC_02697 3.49e-293 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
KGMEOLOC_02698 3.66e-156 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
KGMEOLOC_02699 1.83e-102 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
KGMEOLOC_02700 2.23e-70 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
KGMEOLOC_02701 2.06e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
KGMEOLOC_02702 1.54e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
KGMEOLOC_02703 5.9e-58 ytxJ - - O - - - Protein of unknown function (DUF2847)
KGMEOLOC_02704 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
KGMEOLOC_02705 5.38e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KGMEOLOC_02706 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
KGMEOLOC_02707 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KGMEOLOC_02708 2.08e-139 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KGMEOLOC_02709 1.69e-190 ytpQ - - S - - - Belongs to the UPF0354 family
KGMEOLOC_02710 5.47e-76 ytpP - - CO - - - Thioredoxin
KGMEOLOC_02711 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
KGMEOLOC_02712 4.33e-260 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
KGMEOLOC_02713 9.96e-69 ytzB - - S - - - small secreted protein
KGMEOLOC_02714 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
KGMEOLOC_02715 6.76e-212 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KGMEOLOC_02716 6.43e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KGMEOLOC_02717 6.69e-61 ytzH - - S - - - YtzH-like protein
KGMEOLOC_02718 2.93e-199 ytmP - - M - - - Phosphotransferase
KGMEOLOC_02719 6.37e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
KGMEOLOC_02720 5.36e-219 ytlQ - - - - - - -
KGMEOLOC_02721 3.82e-133 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KGMEOLOC_02722 2.38e-222 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KGMEOLOC_02723 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
KGMEOLOC_02724 1.48e-290 pbuO - - S ko:K06901 - ko00000,ko02000 permease
KGMEOLOC_02725 9.45e-281 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
KGMEOLOC_02726 2.31e-166 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KGMEOLOC_02727 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
KGMEOLOC_02728 8.68e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KGMEOLOC_02729 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KGMEOLOC_02730 7.18e-267 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
KGMEOLOC_02731 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
KGMEOLOC_02732 2.14e-36 yteV - - S - - - Sporulation protein Cse60
KGMEOLOC_02733 1.35e-239 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KGMEOLOC_02734 1.44e-313 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KGMEOLOC_02735 6.79e-219 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KGMEOLOC_02736 1.01e-184 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
KGMEOLOC_02737 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
KGMEOLOC_02738 2.06e-112 - - - M - - - Acetyltransferase (GNAT) domain
KGMEOLOC_02739 6.05e-69 ytwF - - P - - - Sulfurtransferase
KGMEOLOC_02740 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
KGMEOLOC_02741 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
KGMEOLOC_02742 3.72e-178 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
KGMEOLOC_02743 2.46e-271 yttB - - EGP - - - Major facilitator superfamily
KGMEOLOC_02744 2.13e-169 ywaF - - S - - - Integral membrane protein
KGMEOLOC_02745 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
KGMEOLOC_02746 2.3e-174 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
KGMEOLOC_02747 2.23e-224 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
KGMEOLOC_02748 1.57e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGMEOLOC_02749 4.75e-288 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
KGMEOLOC_02750 2.12e-161 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KGMEOLOC_02751 1.7e-214 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
KGMEOLOC_02752 2.47e-209 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KGMEOLOC_02753 2.81e-229 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KGMEOLOC_02754 4.38e-209 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KGMEOLOC_02755 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
KGMEOLOC_02757 7.09e-53 ytzC - - S - - - Protein of unknown function (DUF2524)
KGMEOLOC_02758 0.0 - - - IQ - - - AMP-binding enzyme
KGMEOLOC_02759 1.35e-185 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KGMEOLOC_02760 1.14e-47 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KGMEOLOC_02761 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KGMEOLOC_02762 2.63e-121 - - - Q ko:K04784,ko:K12240 ko01053,map01053 ko00000,ko00001,ko01004,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGMEOLOC_02763 0.0 - - - Q ko:K04784,ko:K12240 ko01053,map01053 ko00000,ko00001,ko01004,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGMEOLOC_02764 0.0 - - - Q ko:K04784,ko:K12240 ko01053,map01053 ko00000,ko00001,ko01004,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGMEOLOC_02765 2.92e-136 - - - C - - - Nitroreductase
KGMEOLOC_02766 4.17e-67 - - - C - - - Nitroreductase
KGMEOLOC_02767 1.02e-169 aveG - - Q - - - Thioesterase domain
KGMEOLOC_02768 0.0 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KGMEOLOC_02769 5.76e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
KGMEOLOC_02770 1.08e-137 ytqB - - J - - - Putative rRNA methylase
KGMEOLOC_02772 1.1e-186 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
KGMEOLOC_02773 2.45e-272 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
KGMEOLOC_02774 6.95e-194 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
KGMEOLOC_02775 4.06e-84 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KGMEOLOC_02776 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KGMEOLOC_02777 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KGMEOLOC_02778 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KGMEOLOC_02779 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KGMEOLOC_02780 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
KGMEOLOC_02781 4.02e-192 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
KGMEOLOC_02782 3.88e-240 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KGMEOLOC_02783 2.6e-185 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KGMEOLOC_02784 2.19e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KGMEOLOC_02785 1.01e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
KGMEOLOC_02786 2.12e-80 ytkC - - S - - - Bacteriophage holin family
KGMEOLOC_02787 3.12e-100 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
KGMEOLOC_02789 4.4e-101 ytkA - - S - - - YtkA-like
KGMEOLOC_02790 7.16e-114 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KGMEOLOC_02791 8.41e-54 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
KGMEOLOC_02792 9.31e-137 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
KGMEOLOC_02793 1.23e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
KGMEOLOC_02794 2.22e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
KGMEOLOC_02795 3.85e-237 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
KGMEOLOC_02796 1.92e-34 - - - S - - - Domain of Unknown Function (DUF1540)
KGMEOLOC_02797 1.74e-273 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KGMEOLOC_02798 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KGMEOLOC_02799 7.52e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KGMEOLOC_02800 7.53e-201 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
KGMEOLOC_02801 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KGMEOLOC_02802 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
KGMEOLOC_02803 1.28e-170 yteA - - T - - - COG1734 DnaK suppressor protein
KGMEOLOC_02804 7.73e-104 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
KGMEOLOC_02824 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
KGMEOLOC_02825 1.46e-126 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
KGMEOLOC_02826 1.6e-279 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
KGMEOLOC_02827 1.68e-110 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
KGMEOLOC_02828 4.6e-108 yuaE - - S - - - DinB superfamily
KGMEOLOC_02829 1.67e-141 - - - S - - - MOSC domain
KGMEOLOC_02830 1.74e-290 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
KGMEOLOC_02831 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KGMEOLOC_02832 3.51e-125 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
KGMEOLOC_02833 2.03e-122 yuaB - - - - - - -
KGMEOLOC_02834 2.6e-157 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
KGMEOLOC_02835 1.62e-194 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KGMEOLOC_02836 1.52e-284 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KGMEOLOC_02837 5.74e-161 - - - G - - - Cupin
KGMEOLOC_02838 1.64e-72 yjcN - - - - - - -
KGMEOLOC_02840 6.56e-187 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KGMEOLOC_02841 6.02e-252 yubA - - S - - - transporter activity
KGMEOLOC_02842 2.84e-239 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
KGMEOLOC_02843 6.95e-127 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
KGMEOLOC_02845 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KGMEOLOC_02846 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KGMEOLOC_02847 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KGMEOLOC_02848 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KGMEOLOC_02849 3.28e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
KGMEOLOC_02850 1.61e-55 - - - - - - - -
KGMEOLOC_02851 6.26e-246 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KGMEOLOC_02852 1.83e-101 yugU - - S - - - Uncharacterised protein family UPF0047
KGMEOLOC_02853 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
KGMEOLOC_02854 1.63e-296 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
KGMEOLOC_02855 1.67e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
KGMEOLOC_02856 1.24e-22 - - - - - - - -
KGMEOLOC_02857 2.44e-35 mstX - - S - - - Membrane-integrating protein Mistic
KGMEOLOC_02858 8.37e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
KGMEOLOC_02859 2.09e-95 yugN - - S - - - YugN-like family
KGMEOLOC_02861 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
KGMEOLOC_02862 6.81e-134 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
KGMEOLOC_02863 2.15e-152 ycaC - - Q - - - Isochorismatase family
KGMEOLOC_02864 1.37e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
KGMEOLOC_02865 4.92e-288 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
KGMEOLOC_02866 4.88e-82 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
KGMEOLOC_02867 2.59e-270 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
KGMEOLOC_02868 3.75e-109 alaR - - K - - - Transcriptional regulator
KGMEOLOC_02869 9.89e-201 yugF - - I - - - Hydrolase
KGMEOLOC_02870 4.25e-55 yugE - - S - - - Domain of unknown function (DUF1871)
KGMEOLOC_02871 8.16e-287 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KGMEOLOC_02872 7.71e-294 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KGMEOLOC_02873 2.05e-90 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
KGMEOLOC_02874 3.22e-152 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
KGMEOLOC_02875 2.25e-264 yuxJ - - EGP - - - Major facilitator superfamily
KGMEOLOC_02876 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
KGMEOLOC_02877 1.85e-95 yuxK - - S - - - protein conserved in bacteria
KGMEOLOC_02878 1.6e-101 yufK - - S - - - Family of unknown function (DUF5366)
KGMEOLOC_02879 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
KGMEOLOC_02880 5.63e-163 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
KGMEOLOC_02881 1.74e-250 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
KGMEOLOC_02882 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KGMEOLOC_02883 2.72e-238 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KGMEOLOC_02884 4.39e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KGMEOLOC_02886 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KGMEOLOC_02887 5.39e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KGMEOLOC_02888 1.47e-67 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KGMEOLOC_02889 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KGMEOLOC_02890 6.08e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KGMEOLOC_02891 1.91e-52 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KGMEOLOC_02892 4.2e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
KGMEOLOC_02893 1.45e-85 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
KGMEOLOC_02894 8.07e-148 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KGMEOLOC_02895 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KGMEOLOC_02897 6.09e-184 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
KGMEOLOC_02898 2.66e-11 - - - S - - - DegQ (SacQ) family
KGMEOLOC_02899 7.9e-72 yuzC - - - - - - -
KGMEOLOC_02900 6.86e-296 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
KGMEOLOC_02901 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KGMEOLOC_02902 8.02e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
KGMEOLOC_02903 7.94e-90 yueI - - S - - - Protein of unknown function (DUF1694)
KGMEOLOC_02904 5.46e-51 yueH - - S - - - YueH-like protein
KGMEOLOC_02905 6.33e-46 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
KGMEOLOC_02906 1.14e-239 yueF - - S - - - transporter activity
KGMEOLOC_02907 1.98e-31 - - - S - - - Protein of unknown function (DUF2642)
KGMEOLOC_02908 1.57e-124 yueE - - S ko:K06950 - ko00000 phosphohydrolase
KGMEOLOC_02909 8.67e-171 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGMEOLOC_02910 1.38e-102 yueC - - S - - - Family of unknown function (DUF5383)
KGMEOLOC_02911 0.0 yueB - - S - - - type VII secretion protein EsaA
KGMEOLOC_02912 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KGMEOLOC_02913 3.38e-277 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
KGMEOLOC_02914 9.1e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
KGMEOLOC_02915 2.36e-61 yukE - - S - - - Belongs to the WXG100 family
KGMEOLOC_02916 3.81e-294 yukF - - QT - - - Transcriptional regulator
KGMEOLOC_02917 5.7e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
KGMEOLOC_02918 1.84e-172 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
KGMEOLOC_02919 2.82e-48 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
KGMEOLOC_02920 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGMEOLOC_02921 5.21e-225 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
KGMEOLOC_02922 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
KGMEOLOC_02923 4.07e-288 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
KGMEOLOC_02924 1.1e-174 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KGMEOLOC_02925 1.53e-212 eSD - - S ko:K07017 - ko00000 Putative esterase
KGMEOLOC_02926 1.13e-155 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
KGMEOLOC_02927 3.73e-131 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
KGMEOLOC_02928 2.01e-276 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
KGMEOLOC_02929 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KGMEOLOC_02930 2.47e-101 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
KGMEOLOC_02931 7.23e-155 yuiC - - S - - - protein conserved in bacteria
KGMEOLOC_02932 8.54e-46 yuiB - - S - - - Putative membrane protein
KGMEOLOC_02933 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KGMEOLOC_02934 1.03e-238 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
KGMEOLOC_02936 6.74e-197 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KGMEOLOC_02937 3.35e-28 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KGMEOLOC_02938 5.68e-40 - - - - - - - -
KGMEOLOC_02939 5.08e-94 - - - CP - - - Membrane
KGMEOLOC_02940 4.11e-160 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KGMEOLOC_02942 5.3e-44 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
KGMEOLOC_02944 5.25e-125 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
KGMEOLOC_02945 3.83e-179 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KGMEOLOC_02946 1.38e-82 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
KGMEOLOC_02947 5.54e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KGMEOLOC_02948 1.49e-273 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KGMEOLOC_02949 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
KGMEOLOC_02950 1.46e-266 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KGMEOLOC_02951 8.37e-76 yuzD - - S - - - protein conserved in bacteria
KGMEOLOC_02952 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
KGMEOLOC_02953 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
KGMEOLOC_02954 4.08e-218 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KGMEOLOC_02955 1.19e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KGMEOLOC_02956 3.03e-299 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
KGMEOLOC_02957 5.4e-251 yutH - - S - - - Spore coat protein
KGMEOLOC_02958 2.59e-110 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
KGMEOLOC_02959 4.31e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KGMEOLOC_02960 4.06e-86 yutE - - S - - - Protein of unknown function DUF86
KGMEOLOC_02961 3.71e-62 yutD - - S - - - protein conserved in bacteria
KGMEOLOC_02962 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KGMEOLOC_02963 1e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
KGMEOLOC_02964 2.87e-169 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
KGMEOLOC_02965 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KGMEOLOC_02966 3.01e-186 yunE - - S ko:K07090 - ko00000 membrane transporter protein
KGMEOLOC_02967 1.54e-218 yunF - - S - - - Protein of unknown function DUF72
KGMEOLOC_02968 7.74e-83 - - - S - - - phosphoglycolate phosphatase activity
KGMEOLOC_02969 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
KGMEOLOC_02970 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
KGMEOLOC_02971 6.36e-97 - - - - - - - -
KGMEOLOC_02973 4.47e-276 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
KGMEOLOC_02974 2.64e-305 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KGMEOLOC_02975 1.3e-303 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KGMEOLOC_02976 2.46e-218 bsn - - L - - - Ribonuclease
KGMEOLOC_02977 1.41e-266 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KGMEOLOC_02978 5.89e-173 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
KGMEOLOC_02979 2.63e-206 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
KGMEOLOC_02980 8.84e-210 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
KGMEOLOC_02981 5.26e-203 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KGMEOLOC_02982 1.36e-315 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
KGMEOLOC_02983 2.84e-239 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
KGMEOLOC_02984 2.01e-213 - - - K - - - helix_turn_helix, mercury resistance
KGMEOLOC_02987 5.74e-86 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
KGMEOLOC_02988 4.91e-264 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
KGMEOLOC_02989 7.94e-168 - - - Q - - - ubiE/COQ5 methyltransferase family
KGMEOLOC_02990 2.94e-111 yncE - - S - - - Protein of unknown function (DUF2691)
KGMEOLOC_02991 5.3e-203 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
KGMEOLOC_02992 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
KGMEOLOC_02993 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
KGMEOLOC_02994 2.31e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KGMEOLOC_02995 1.23e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
KGMEOLOC_02996 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KGMEOLOC_02997 8.85e-85 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KGMEOLOC_02998 4.46e-187 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
KGMEOLOC_02999 1.46e-138 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
KGMEOLOC_03000 3.71e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KGMEOLOC_03001 1.29e-76 yusD - - S - - - SCP-2 sterol transfer family
KGMEOLOC_03002 1.64e-72 yusE - - CO - - - Thioredoxin
KGMEOLOC_03003 1.08e-82 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
KGMEOLOC_03004 7.61e-56 yusG - - S - - - Protein of unknown function (DUF2553)
KGMEOLOC_03005 4.16e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
KGMEOLOC_03006 7.13e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
KGMEOLOC_03007 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
KGMEOLOC_03008 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
KGMEOLOC_03009 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
KGMEOLOC_03010 1.12e-216 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
KGMEOLOC_03011 2.25e-58 - - - - - - - -
KGMEOLOC_03012 4.46e-72 yusN - - M - - - Coat F domain
KGMEOLOC_03013 9.65e-92 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
KGMEOLOC_03014 0.0 yusP - - P - - - Major facilitator superfamily
KGMEOLOC_03015 1.57e-89 yusQ - - S - - - Tautomerase enzyme
KGMEOLOC_03016 7.69e-171 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
KGMEOLOC_03017 2.44e-206 yusT - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
KGMEOLOC_03018 1.3e-207 - - - K - - - Transcriptional regulator
KGMEOLOC_03019 1.29e-179 - 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
KGMEOLOC_03020 1.78e-242 apbA 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KGMEOLOC_03021 2.15e-52 yusU - - S - - - Protein of unknown function (DUF2573)
KGMEOLOC_03022 1.29e-192 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KGMEOLOC_03023 3.77e-60 - - - S - - - YusW-like protein
KGMEOLOC_03024 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
KGMEOLOC_03025 5.7e-199 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KGMEOLOC_03026 4.66e-105 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
KGMEOLOC_03027 8.31e-309 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KGMEOLOC_03028 3.17e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGMEOLOC_03029 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KGMEOLOC_03030 4.63e-33 - - - - - - - -
KGMEOLOC_03031 3.11e-201 yuxN - - K - - - Transcriptional regulator
KGMEOLOC_03032 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KGMEOLOC_03033 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
KGMEOLOC_03034 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
KGMEOLOC_03035 1.12e-246 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
KGMEOLOC_03036 1.04e-269 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
KGMEOLOC_03037 7.15e-140 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KGMEOLOC_03038 8.56e-248 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KGMEOLOC_03039 1.54e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
KGMEOLOC_03040 2.12e-194 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
KGMEOLOC_03041 9.74e-134 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
KGMEOLOC_03042 1.62e-68 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
KGMEOLOC_03043 7.41e-294 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KGMEOLOC_03044 3.23e-133 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
KGMEOLOC_03045 4.6e-290 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
KGMEOLOC_03046 8.32e-233 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KGMEOLOC_03047 1.16e-215 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KGMEOLOC_03048 1.23e-180 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KGMEOLOC_03049 2.28e-220 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
KGMEOLOC_03050 0.0 yvrG - - T - - - Histidine kinase
KGMEOLOC_03051 2.7e-172 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGMEOLOC_03052 3.23e-134 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
KGMEOLOC_03053 1.88e-21 - - - S - - - YvrJ protein family
KGMEOLOC_03054 1.08e-295 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
KGMEOLOC_03055 7.16e-90 yvrL - - S - - - Regulatory protein YrvL
KGMEOLOC_03056 2.4e-189 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KGMEOLOC_03057 1.17e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KGMEOLOC_03058 3.29e-238 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KGMEOLOC_03059 2.21e-228 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KGMEOLOC_03060 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
KGMEOLOC_03061 1.06e-19 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
KGMEOLOC_03062 1.01e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
KGMEOLOC_03063 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
KGMEOLOC_03064 6e-215 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
KGMEOLOC_03065 2.89e-180 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
KGMEOLOC_03066 2.84e-127 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
KGMEOLOC_03067 1.06e-148 yfiK - - K - - - Regulator
KGMEOLOC_03068 4.66e-257 - - - T - - - Histidine kinase
KGMEOLOC_03069 4.97e-220 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
KGMEOLOC_03070 3.65e-251 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
KGMEOLOC_03071 4.36e-263 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
KGMEOLOC_03072 1.77e-200 yvgN - - S - - - reductase
KGMEOLOC_03073 9.69e-114 yvgO - - - - - - -
KGMEOLOC_03074 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
KGMEOLOC_03075 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
KGMEOLOC_03076 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KGMEOLOC_03077 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KGMEOLOC_03078 2.24e-139 yvgT - - S - - - membrane
KGMEOLOC_03079 2.42e-193 - - - S - - - Metallo-peptidase family M12
KGMEOLOC_03080 1.83e-96 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
KGMEOLOC_03081 3.33e-140 bdbD - - O - - - Thioredoxin
KGMEOLOC_03082 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
KGMEOLOC_03083 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
KGMEOLOC_03084 3.24e-40 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
KGMEOLOC_03085 2.81e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
KGMEOLOC_03086 8.97e-252 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
KGMEOLOC_03087 3.59e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KGMEOLOC_03088 2.17e-209 - - - K - - - Helix-turn-helix XRE-family like proteins
KGMEOLOC_03089 9.17e-284 - - - EGP - - - Major Facilitator Superfamily
KGMEOLOC_03090 9.11e-92 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
KGMEOLOC_03091 4.33e-189 - - - S ko:K07045 - ko00000 Amidohydrolase
KGMEOLOC_03092 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KGMEOLOC_03093 1.49e-63 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
KGMEOLOC_03094 9.08e-235 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KGMEOLOC_03095 1.56e-181 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KGMEOLOC_03096 1.42e-156 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KGMEOLOC_03097 4.4e-158 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KGMEOLOC_03098 3.16e-191 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
KGMEOLOC_03099 7.17e-172 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
KGMEOLOC_03100 1.57e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
KGMEOLOC_03101 6.64e-211 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
KGMEOLOC_03102 4.79e-181 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
KGMEOLOC_03103 1.1e-70 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
KGMEOLOC_03105 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KGMEOLOC_03106 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KGMEOLOC_03107 1.7e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
KGMEOLOC_03108 4.58e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
KGMEOLOC_03109 1.64e-47 yvzC - - K - - - transcriptional
KGMEOLOC_03110 1.29e-87 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
KGMEOLOC_03111 4.28e-97 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
KGMEOLOC_03112 2.97e-70 yvaP - - K - - - transcriptional
KGMEOLOC_03113 0.0 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
KGMEOLOC_03114 4.69e-159 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
KGMEOLOC_03115 1.44e-180 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KGMEOLOC_03116 3.92e-163 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KGMEOLOC_03117 4.62e-163 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KGMEOLOC_03118 2.09e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KGMEOLOC_03119 6.83e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KGMEOLOC_03120 2.39e-146 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KGMEOLOC_03121 8.57e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KGMEOLOC_03122 3.42e-124 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
KGMEOLOC_03123 2.64e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KGMEOLOC_03124 6.83e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KGMEOLOC_03125 1.61e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KGMEOLOC_03126 5.16e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KGMEOLOC_03127 1.01e-129 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
KGMEOLOC_03128 1.88e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
KGMEOLOC_03129 1.32e-157 yvbI - - M - - - Membrane
KGMEOLOC_03130 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
KGMEOLOC_03131 1.11e-106 yvbK - - K - - - acetyltransferase
KGMEOLOC_03132 1.14e-271 - - - EGP - - - Major facilitator Superfamily
KGMEOLOC_03133 1.02e-230 - - - - - - - -
KGMEOLOC_03134 1.9e-163 - - - S - - - GlcNAc-PI de-N-acetylase
KGMEOLOC_03135 2.89e-185 - - - C - - - WbqC-like protein family
KGMEOLOC_03136 3.92e-192 - - - M - - - Protein involved in cellulose biosynthesis
KGMEOLOC_03137 1.41e-305 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KGMEOLOC_03138 8.95e-222 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
KGMEOLOC_03139 1.19e-278 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
KGMEOLOC_03140 2.82e-204 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KGMEOLOC_03141 4.83e-100 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KGMEOLOC_03142 1.12e-308 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
KGMEOLOC_03143 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KGMEOLOC_03144 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
KGMEOLOC_03145 2.58e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KGMEOLOC_03146 2.8e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
KGMEOLOC_03147 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KGMEOLOC_03148 2.95e-240 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KGMEOLOC_03150 0.0 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KGMEOLOC_03151 2.33e-262 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
KGMEOLOC_03152 5.33e-243 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KGMEOLOC_03154 9.08e-202 yvbU - - K - - - Transcriptional regulator
KGMEOLOC_03155 1.08e-200 yvbV - - EG - - - EamA-like transporter family
KGMEOLOC_03156 4.71e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KGMEOLOC_03157 0.0 - - - - - - - -
KGMEOLOC_03158 1.91e-235 yhjM - - K - - - Transcriptional regulator
KGMEOLOC_03159 1.55e-149 - - - S ko:K07149 - ko00000 Membrane
KGMEOLOC_03160 1.08e-215 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
KGMEOLOC_03161 8.05e-197 gntR - - K - - - RpiR family transcriptional regulator
KGMEOLOC_03162 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
KGMEOLOC_03163 2.89e-292 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
KGMEOLOC_03164 1.23e-173 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KGMEOLOC_03165 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
KGMEOLOC_03166 2.14e-173 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KGMEOLOC_03167 4.23e-289 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KGMEOLOC_03168 5.36e-157 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
KGMEOLOC_03169 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
KGMEOLOC_03170 7.14e-313 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KGMEOLOC_03171 9.82e-45 yvfG - - S - - - YvfG protein
KGMEOLOC_03172 7.27e-243 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
KGMEOLOC_03173 3.31e-283 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
KGMEOLOC_03174 6.08e-81 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
KGMEOLOC_03175 9.52e-141 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KGMEOLOC_03176 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KGMEOLOC_03177 1.68e-255 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
KGMEOLOC_03178 4.18e-263 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
KGMEOLOC_03179 2.04e-252 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
KGMEOLOC_03180 1.46e-263 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
KGMEOLOC_03181 3.27e-277 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
KGMEOLOC_03182 2.74e-206 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
KGMEOLOC_03183 4.01e-283 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
KGMEOLOC_03184 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
KGMEOLOC_03185 7.67e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
KGMEOLOC_03186 8.04e-136 epsA - - M ko:K19420 - ko00000 biosynthesis protein
KGMEOLOC_03187 5.95e-101 - - - K ko:K19417 - ko00000,ko03000 transcriptional
KGMEOLOC_03188 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
KGMEOLOC_03189 1.7e-128 ywjB - - H - - - RibD C-terminal domain
KGMEOLOC_03190 1.84e-146 yyaS - - S ko:K07149 - ko00000 Membrane
KGMEOLOC_03191 1.15e-120 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KGMEOLOC_03192 2.47e-121 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
KGMEOLOC_03194 2.64e-54 - - - S - - - Protein of unknown function (DUF1433)
KGMEOLOC_03195 4.11e-57 - - - I - - - Pfam Lipase (class 3)
KGMEOLOC_03196 2.8e-16 - - - S - - - Protein of unknown function (DUF1433)
KGMEOLOC_03197 0.0 - - - I - - - Pfam Lipase (class 3)
KGMEOLOC_03198 3.92e-47 - - - - - - - -
KGMEOLOC_03200 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
KGMEOLOC_03201 2.45e-286 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
KGMEOLOC_03202 4.69e-236 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
KGMEOLOC_03203 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KGMEOLOC_03204 3.34e-210 yraN - - K - - - Transcriptional regulator
KGMEOLOC_03205 6.58e-276 yraM - - S - - - PrpF protein
KGMEOLOC_03206 2.9e-315 - - - EGP - - - Sugar (and other) transporter
KGMEOLOC_03207 1.32e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
KGMEOLOC_03208 3.2e-70 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
KGMEOLOC_03209 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
KGMEOLOC_03210 4.41e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
KGMEOLOC_03211 2.51e-234 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KGMEOLOC_03212 5.54e-105 - - - M - - - Ribonuclease
KGMEOLOC_03213 6.92e-184 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
KGMEOLOC_03214 2.76e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
KGMEOLOC_03215 5.16e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
KGMEOLOC_03216 8.28e-45 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
KGMEOLOC_03217 7.92e-146 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
KGMEOLOC_03218 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
KGMEOLOC_03219 5.15e-113 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KGMEOLOC_03220 3.13e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KGMEOLOC_03221 1.86e-204 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
KGMEOLOC_03222 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
KGMEOLOC_03223 2.02e-247 sasA - - T - - - Histidine kinase
KGMEOLOC_03224 3.99e-158 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGMEOLOC_03225 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
KGMEOLOC_03226 1.71e-145 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
KGMEOLOC_03227 2.39e-177 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KGMEOLOC_03228 4.81e-169 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KGMEOLOC_03229 2.51e-150 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KGMEOLOC_03230 1.17e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
KGMEOLOC_03231 9.92e-302 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KGMEOLOC_03232 1.83e-148 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KGMEOLOC_03233 6.03e-270 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KGMEOLOC_03234 3.56e-178 yvpB - - NU - - - protein conserved in bacteria
KGMEOLOC_03235 1.07e-115 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
KGMEOLOC_03236 8.12e-158 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
KGMEOLOC_03237 1.84e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KGMEOLOC_03238 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KGMEOLOC_03239 1.27e-290 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
KGMEOLOC_03240 9.42e-174 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KGMEOLOC_03241 1.05e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
KGMEOLOC_03242 1.54e-136 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
KGMEOLOC_03243 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
KGMEOLOC_03244 7.66e-66 yvlD - - S ko:K08972 - ko00000 Membrane
KGMEOLOC_03245 4.01e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
KGMEOLOC_03246 5.54e-219 yvlB - - S - - - Putative adhesin
KGMEOLOC_03247 4.87e-66 yvlA - - - - - - -
KGMEOLOC_03248 1.78e-51 yvkN - - - - - - -
KGMEOLOC_03249 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KGMEOLOC_03250 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KGMEOLOC_03251 2.59e-45 csbA - - S - - - protein conserved in bacteria
KGMEOLOC_03252 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
KGMEOLOC_03253 2.7e-54 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
KGMEOLOC_03254 2.32e-144 yvkB - - K - - - Transcriptional regulator
KGMEOLOC_03255 1.45e-298 yvkA - - P - - - -transporter
KGMEOLOC_03256 5.02e-269 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KGMEOLOC_03257 4.26e-74 swrA - - S - - - Swarming motility protein
KGMEOLOC_03258 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
KGMEOLOC_03259 9.32e-309 ywoF - - P - - - Right handed beta helix region
KGMEOLOC_03260 7.34e-197 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KGMEOLOC_03261 8.68e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
KGMEOLOC_03262 3.08e-60 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
KGMEOLOC_03263 4.82e-192 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KGMEOLOC_03264 6.64e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KGMEOLOC_03265 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KGMEOLOC_03266 3.94e-133 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KGMEOLOC_03267 1.1e-10 fliT - - N ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
KGMEOLOC_03268 5.79e-88 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
KGMEOLOC_03269 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KGMEOLOC_03270 9.78e-173 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KGMEOLOC_03271 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KGMEOLOC_03272 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KGMEOLOC_03273 5.9e-110 yviE - - - - - - -
KGMEOLOC_03274 8.44e-209 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
KGMEOLOC_03275 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
KGMEOLOC_03276 2.2e-105 yvyG - - NOU - - - FlgN protein
KGMEOLOC_03277 6.14e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
KGMEOLOC_03278 5.47e-98 yvyF - - S - - - flagellar protein
KGMEOLOC_03279 2.13e-101 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
KGMEOLOC_03280 2.14e-58 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
KGMEOLOC_03281 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KGMEOLOC_03282 8.81e-204 degV - - S - - - protein conserved in bacteria
KGMEOLOC_03283 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KGMEOLOC_03284 3.44e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KGMEOLOC_03285 2.94e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
KGMEOLOC_03286 2.6e-240 yvhJ - - K - - - Transcriptional regulator
KGMEOLOC_03287 3.12e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
KGMEOLOC_03288 1.2e-305 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
KGMEOLOC_03289 6.92e-186 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
KGMEOLOC_03290 8.95e-151 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
KGMEOLOC_03291 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
KGMEOLOC_03292 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KGMEOLOC_03293 7.03e-289 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
KGMEOLOC_03294 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KGMEOLOC_03295 4.22e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KGMEOLOC_03296 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
KGMEOLOC_03297 0.0 lytB - - D - - - Stage II sporulation protein
KGMEOLOC_03298 3.22e-65 - - - - - - - -
KGMEOLOC_03299 4.48e-204 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KGMEOLOC_03300 1.88e-272 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KGMEOLOC_03301 2.64e-211 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KGMEOLOC_03302 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KGMEOLOC_03303 5.06e-195 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
KGMEOLOC_03304 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KGMEOLOC_03305 0.0 - - - M - - - Glycosyltransferase like family 2
KGMEOLOC_03306 4.06e-55 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
KGMEOLOC_03307 8.6e-26 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
KGMEOLOC_03308 6.38e-184 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KGMEOLOC_03309 1.57e-280 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KGMEOLOC_03310 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KGMEOLOC_03311 2.43e-243 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KGMEOLOC_03312 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
KGMEOLOC_03313 4.65e-256 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
KGMEOLOC_03314 1.09e-274 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
KGMEOLOC_03315 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
KGMEOLOC_03316 4.54e-316 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KGMEOLOC_03317 9.77e-231 ywtF_2 - - K - - - Transcriptional regulator
KGMEOLOC_03318 3.88e-204 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
KGMEOLOC_03319 4.5e-80 yttA - - S - - - Pfam Transposase IS66
KGMEOLOC_03320 2.85e-306 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KGMEOLOC_03321 4.04e-29 ywtC - - - - - - -
KGMEOLOC_03322 1.39e-280 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
KGMEOLOC_03323 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
KGMEOLOC_03324 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
KGMEOLOC_03325 2.54e-241 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
KGMEOLOC_03326 1.08e-247 - - - E - - - Spore germination protein
KGMEOLOC_03327 2.25e-263 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
KGMEOLOC_03328 1.1e-230 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
KGMEOLOC_03329 1.77e-204 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KGMEOLOC_03330 5.83e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KGMEOLOC_03331 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KGMEOLOC_03332 1.87e-205 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KGMEOLOC_03333 1.2e-208 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
KGMEOLOC_03334 2.49e-117 batE - - T - - - Sh3 type 3 domain protein
KGMEOLOC_03335 1.5e-124 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
KGMEOLOC_03336 5.71e-191 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
KGMEOLOC_03337 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
KGMEOLOC_03338 5.35e-215 alsR - - K - - - LysR substrate binding domain
KGMEOLOC_03339 1.27e-307 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KGMEOLOC_03340 3.79e-63 ywrJ - - - - - - -
KGMEOLOC_03341 1.84e-42 ywrJ - - - - - - -
KGMEOLOC_03342 1.22e-192 cotB - - - ko:K06325 - ko00000 -
KGMEOLOC_03343 4.09e-273 cotH - - M ko:K06330 - ko00000 Spore Coat
KGMEOLOC_03344 4.38e-15 - - - - - - - -
KGMEOLOC_03345 6.96e-145 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KGMEOLOC_03346 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
KGMEOLOC_03347 3.53e-110 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
KGMEOLOC_03348 4.38e-134 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
KGMEOLOC_03349 8.99e-116 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
KGMEOLOC_03350 4.5e-175 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
KGMEOLOC_03351 9.61e-121 - - - - - - - -
KGMEOLOC_03352 2.28e-63 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
KGMEOLOC_03353 6.63e-137 - - - S - - - Domain of unknown function (DUF1851)
KGMEOLOC_03354 9.84e-96 - - - S - - - LXG domain of WXG superfamily
KGMEOLOC_03355 2.01e-110 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
KGMEOLOC_03356 4.55e-121 - - - - - - - -
KGMEOLOC_03357 2.05e-66 - - - - - - - -
KGMEOLOC_03358 0.0 ywqJ - - S - - - Pre-toxin TG
KGMEOLOC_03359 2.09e-50 ywqI - - S - - - Family of unknown function (DUF5344)
KGMEOLOC_03362 1.84e-195 ywqG - - S - - - Domain of unknown function (DUF1963)
KGMEOLOC_03363 9.43e-316 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KGMEOLOC_03364 7.76e-184 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
KGMEOLOC_03365 2.69e-158 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
KGMEOLOC_03366 3.53e-152 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
KGMEOLOC_03367 1.74e-21 - - - - - - - -
KGMEOLOC_03368 0.0 ywqB - - S - - - SWIM zinc finger
KGMEOLOC_03369 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
KGMEOLOC_03370 9.52e-205 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
KGMEOLOC_03371 1.18e-181 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
KGMEOLOC_03372 1.79e-77 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
KGMEOLOC_03373 4.49e-82 ywpG - - - - - - -
KGMEOLOC_03374 9.16e-91 ywpF - - S - - - YwpF-like protein
KGMEOLOC_03375 1.87e-74 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KGMEOLOC_03376 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KGMEOLOC_03377 1.11e-58 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
KGMEOLOC_03378 9.92e-181 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
KGMEOLOC_03379 1.14e-188 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
KGMEOLOC_03380 1.03e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
KGMEOLOC_03381 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
KGMEOLOC_03382 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
KGMEOLOC_03383 3.58e-93 ywoH - - K - - - transcriptional
KGMEOLOC_03384 2.89e-272 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KGMEOLOC_03385 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
KGMEOLOC_03386 1.98e-312 ywoD - - EGP - - - Major facilitator superfamily
KGMEOLOC_03387 1.37e-133 yjgF - - Q - - - Isochorismatase family
KGMEOLOC_03388 1.32e-291 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
KGMEOLOC_03389 1.29e-76 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
KGMEOLOC_03390 2.09e-267 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KGMEOLOC_03391 5.79e-132 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
KGMEOLOC_03392 8.06e-96 ywnJ - - S - - - VanZ like family
KGMEOLOC_03393 1.31e-188 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
KGMEOLOC_03394 4.77e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
KGMEOLOC_03396 2.52e-43 ywnF - - S - - - Family of unknown function (DUF5392)
KGMEOLOC_03397 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KGMEOLOC_03398 2.4e-80 ywnC - - S - - - Family of unknown function (DUF5362)
KGMEOLOC_03399 6.44e-158 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
KGMEOLOC_03400 1.08e-88 ywnA - - K - - - Transcriptional regulator
KGMEOLOC_03401 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KGMEOLOC_03402 1.85e-82 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
KGMEOLOC_03403 2.86e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
KGMEOLOC_03404 2.51e-18 csbD - - K - - - CsbD-like
KGMEOLOC_03405 3.66e-108 ywmF - - S - - - Peptidase M50
KGMEOLOC_03406 6.28e-116 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
KGMEOLOC_03407 1.31e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KGMEOLOC_03408 1.1e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KGMEOLOC_03410 1.5e-158 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
KGMEOLOC_03411 2.59e-160 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
KGMEOLOC_03412 3.47e-243 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
KGMEOLOC_03413 7.05e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KGMEOLOC_03414 3.4e-135 ywmB - - S - - - TATA-box binding
KGMEOLOC_03415 5.7e-29 ywmB - - S - - - TATA-box binding
KGMEOLOC_03416 2.25e-45 ywzB - - S - - - membrane
KGMEOLOC_03417 1.76e-118 ywmA - - - - - - -
KGMEOLOC_03418 8.24e-83 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
KGMEOLOC_03419 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KGMEOLOC_03420 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KGMEOLOC_03421 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KGMEOLOC_03422 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KGMEOLOC_03423 1.66e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KGMEOLOC_03424 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KGMEOLOC_03425 5.19e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
KGMEOLOC_03426 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
KGMEOLOC_03427 2.24e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KGMEOLOC_03428 3.07e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KGMEOLOC_03429 5.12e-123 ywlG - - S - - - Belongs to the UPF0340 family
KGMEOLOC_03430 2.08e-101 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KGMEOLOC_03431 1.17e-119 mntP - - P - - - Probably functions as a manganese efflux pump
KGMEOLOC_03432 6.77e-247 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KGMEOLOC_03433 5.15e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
KGMEOLOC_03434 2.05e-156 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
KGMEOLOC_03435 7.26e-80 ywlA - - S - - - Uncharacterised protein family (UPF0715)
KGMEOLOC_03437 4.19e-204 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KGMEOLOC_03438 1.11e-244 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KGMEOLOC_03439 9.07e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KGMEOLOC_03440 1.04e-123 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
KGMEOLOC_03441 2.02e-202 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
KGMEOLOC_03442 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
KGMEOLOC_03443 5.56e-136 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
KGMEOLOC_03444 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
KGMEOLOC_03445 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KGMEOLOC_03446 1.43e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
KGMEOLOC_03447 3.9e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KGMEOLOC_03448 2.22e-144 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KGMEOLOC_03449 5.51e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
KGMEOLOC_03450 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
KGMEOLOC_03451 8.11e-121 ywjG - - S - - - Domain of unknown function (DUF2529)
KGMEOLOC_03452 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KGMEOLOC_03453 6.53e-80 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KGMEOLOC_03454 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
KGMEOLOC_03455 2.18e-288 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
KGMEOLOC_03456 1.25e-238 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
KGMEOLOC_03457 7.93e-59 ywjC - - - - - - -
KGMEOLOC_03458 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
KGMEOLOC_03459 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KGMEOLOC_03460 1.05e-136 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
KGMEOLOC_03461 2.28e-107 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
KGMEOLOC_03462 2.76e-23 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
KGMEOLOC_03463 8.29e-129 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
KGMEOLOC_03464 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
KGMEOLOC_03465 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KGMEOLOC_03466 2.49e-110 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
KGMEOLOC_03467 2.72e-181 ywiC - - S - - - YwiC-like protein
KGMEOLOC_03468 1.33e-167 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
KGMEOLOC_03469 1.05e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
KGMEOLOC_03470 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
KGMEOLOC_03471 1.14e-96 ywiB - - S - - - protein conserved in bacteria
KGMEOLOC_03473 5.69e-314 ywhL - - CO - - - amine dehydrogenase activity
KGMEOLOC_03474 1.99e-299 ywhK - - CO - - - amine dehydrogenase activity
KGMEOLOC_03475 1.16e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
KGMEOLOC_03477 9.15e-41 ydcG - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
KGMEOLOC_03478 2.41e-45 - - - - - - - -
KGMEOLOC_03479 1.18e-38 - - - S - - - Domain of unknown function (DUF4177)
KGMEOLOC_03481 2.07e-101 - - - CP - - - Membrane
KGMEOLOC_03484 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
KGMEOLOC_03485 1.58e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KGMEOLOC_03486 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KGMEOLOC_03487 7.67e-109 - - - - - - - -
KGMEOLOC_03488 4.38e-91 ywhD - - S - - - YwhD family
KGMEOLOC_03489 2.31e-154 ywhC - - S - - - Peptidase family M50
KGMEOLOC_03490 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
KGMEOLOC_03491 1.02e-93 ywhA - - K - - - Transcriptional regulator
KGMEOLOC_03492 2.71e-316 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
KGMEOLOC_03493 2.02e-115 ywgA - - - ko:K09388 - ko00000 -
KGMEOLOC_03494 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
KGMEOLOC_03495 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
KGMEOLOC_03496 2.48e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
KGMEOLOC_03497 4.58e-69 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
KGMEOLOC_03498 3.23e-121 - - - S - - - membrane
KGMEOLOC_03499 8.51e-214 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KGMEOLOC_03500 1.79e-216 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
KGMEOLOC_03503 1.21e-230 - - - - - - - -
KGMEOLOC_03505 1.58e-204 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
KGMEOLOC_03506 3.89e-211 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
KGMEOLOC_03507 1.85e-217 - - - S - - - Conserved hypothetical protein 698
KGMEOLOC_03508 2.03e-225 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
KGMEOLOC_03509 4.87e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
KGMEOLOC_03510 2.94e-181 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
KGMEOLOC_03511 1.33e-298 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
KGMEOLOC_03512 1.41e-265 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
KGMEOLOC_03513 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
KGMEOLOC_03514 8.05e-181 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGMEOLOC_03515 1.19e-176 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
KGMEOLOC_03516 1.4e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
KGMEOLOC_03517 4.24e-288 ywfA - - EGP - - - -transporter
KGMEOLOC_03518 2.17e-268 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
KGMEOLOC_03519 1.65e-218 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KGMEOLOC_03520 0.0 rocB - - E - - - arginine degradation protein
KGMEOLOC_03521 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
KGMEOLOC_03522 3.15e-314 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KGMEOLOC_03523 3.44e-211 - - - T - - - Histidine kinase
KGMEOLOC_03524 2.59e-162 - - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGMEOLOC_03525 5.52e-61 - - - S - - - Putative adhesin
KGMEOLOC_03526 9.66e-110 - - - - - - - -
KGMEOLOC_03527 1.48e-153 - - - S - - - ABC-2 family transporter protein
KGMEOLOC_03528 2.28e-222 bcrA5 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KGMEOLOC_03529 8.08e-113 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
KGMEOLOC_03530 2.86e-209 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KGMEOLOC_03531 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KGMEOLOC_03532 6.9e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KGMEOLOC_03533 2.97e-244 spsG - - M - - - Spore Coat
KGMEOLOC_03534 2.22e-177 spsF - - M ko:K07257 - ko00000 Spore Coat
KGMEOLOC_03535 3.01e-275 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
KGMEOLOC_03536 9.93e-208 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
KGMEOLOC_03537 5.29e-284 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
KGMEOLOC_03538 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
KGMEOLOC_03539 9.06e-184 spsA - - M - - - Spore Coat
KGMEOLOC_03540 1.49e-89 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
KGMEOLOC_03541 3.75e-77 ywdK - - S - - - small membrane protein
KGMEOLOC_03542 1.19e-294 ywdJ - - F - - - Xanthine uracil
KGMEOLOC_03543 3.04e-62 ywdI - - S - - - Family of unknown function (DUF5327)
KGMEOLOC_03544 7.22e-171 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KGMEOLOC_03545 1.52e-197 ywdF - - S - - - Glycosyltransferase like family 2
KGMEOLOC_03547 3.46e-116 ywdD - - - - - - -
KGMEOLOC_03548 1.6e-75 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
KGMEOLOC_03549 4.13e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KGMEOLOC_03550 3.52e-26 ywdA - - - - - - -
KGMEOLOC_03551 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
KGMEOLOC_03552 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KGMEOLOC_03553 4.68e-196 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
KGMEOLOC_03555 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KGMEOLOC_03556 7.25e-240 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KGMEOLOC_03557 1.55e-72 - - - L - - - COG2963 Transposase and inactivated derivatives
KGMEOLOC_03558 1.96e-150 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
KGMEOLOC_03559 1.14e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
KGMEOLOC_03560 7.63e-271 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
KGMEOLOC_03561 1.2e-106 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
KGMEOLOC_03562 2.54e-51 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
KGMEOLOC_03563 8.22e-85 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
KGMEOLOC_03564 4.91e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
KGMEOLOC_03565 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KGMEOLOC_03566 2.21e-228 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
KGMEOLOC_03567 5.74e-48 ydaS - - S - - - membrane
KGMEOLOC_03568 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
KGMEOLOC_03569 6.52e-292 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KGMEOLOC_03570 5.1e-83 gtcA - - S - - - GtrA-like protein
KGMEOLOC_03571 6.43e-146 - - - K - - - Bacterial regulatory proteins, tetR family
KGMEOLOC_03573 7.5e-168 - - - H - - - Methionine biosynthesis protein MetW
KGMEOLOC_03574 1.03e-173 - - - S - - - Streptomycin biosynthesis protein StrF
KGMEOLOC_03575 3.09e-145 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
KGMEOLOC_03576 9.68e-313 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
KGMEOLOC_03577 5.18e-149 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KGMEOLOC_03578 2.35e-178 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KGMEOLOC_03579 4.83e-202 ywbI - - K - - - Transcriptional regulator
KGMEOLOC_03580 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
KGMEOLOC_03581 6.47e-144 ywbG - - M - - - effector of murein hydrolase
KGMEOLOC_03582 9.1e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
KGMEOLOC_03583 1.02e-183 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
KGMEOLOC_03584 3.65e-221 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
KGMEOLOC_03585 1.53e-286 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
KGMEOLOC_03586 1.29e-88 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
KGMEOLOC_03587 3.28e-315 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KGMEOLOC_03588 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KGMEOLOC_03589 4.43e-209 gspA - - M - - - General stress
KGMEOLOC_03590 1.85e-151 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
KGMEOLOC_03591 7.57e-215 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
KGMEOLOC_03592 7.08e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
KGMEOLOC_03593 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGMEOLOC_03594 2.56e-293 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
KGMEOLOC_03595 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGMEOLOC_03596 1.31e-290 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KGMEOLOC_03597 1.41e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
KGMEOLOC_03598 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KGMEOLOC_03599 2.9e-68 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KGMEOLOC_03600 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KGMEOLOC_03601 4.46e-66 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
KGMEOLOC_03602 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
KGMEOLOC_03603 4.77e-147 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
KGMEOLOC_03604 2e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KGMEOLOC_03605 4.83e-231 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KGMEOLOC_03606 9.23e-214 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
KGMEOLOC_03607 3.3e-79 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
KGMEOLOC_03608 2.8e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KGMEOLOC_03609 1.18e-66 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KGMEOLOC_03610 6.75e-67 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KGMEOLOC_03611 7.31e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KGMEOLOC_03612 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KGMEOLOC_03613 3.93e-217 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
KGMEOLOC_03614 2.17e-245 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KGMEOLOC_03615 6.75e-270 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
KGMEOLOC_03616 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
KGMEOLOC_03617 2.75e-246 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
KGMEOLOC_03618 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
KGMEOLOC_03619 1.85e-202 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KGMEOLOC_03620 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
KGMEOLOC_03621 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
KGMEOLOC_03622 9.56e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
KGMEOLOC_03623 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
KGMEOLOC_03624 4.75e-289 cimH - - C - - - COG3493 Na citrate symporter
KGMEOLOC_03625 1.2e-200 yxkH - - G - - - Polysaccharide deacetylase
KGMEOLOC_03626 6.42e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KGMEOLOC_03627 2.66e-217 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
KGMEOLOC_03628 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
KGMEOLOC_03629 2.68e-120 yxkC - - S - - - Domain of unknown function (DUF4352)
KGMEOLOC_03630 3.94e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KGMEOLOC_03631 8.44e-303 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
KGMEOLOC_03634 7.42e-112 yxjI - - S - - - LURP-one-related
KGMEOLOC_03635 9.77e-279 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
KGMEOLOC_03636 2.65e-215 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
KGMEOLOC_03637 3.47e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KGMEOLOC_03638 3.75e-126 - - - T - - - Domain of unknown function (DUF4163)
KGMEOLOC_03639 1.61e-68 yxiS - - - - - - -
KGMEOLOC_03640 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
KGMEOLOC_03641 2.84e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
KGMEOLOC_03642 1.45e-185 bglS - - M - - - licheninase activity
KGMEOLOC_03643 1.19e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
KGMEOLOC_03644 2.21e-283 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
KGMEOLOC_03645 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
KGMEOLOC_03648 4.25e-82 - - - S - - - SMI1-KNR4 cell-wall
KGMEOLOC_03649 4.01e-118 yxiI - - S - - - Protein of unknown function (DUF2716)
KGMEOLOC_03651 5.75e-98 yxiG - - - - - - -
KGMEOLOC_03652 2.34e-93 yxxG - - - - - - -
KGMEOLOC_03655 1.2e-260 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
KGMEOLOC_03656 1.78e-209 yxxF - - EG - - - EamA-like transporter family
KGMEOLOC_03657 1.26e-96 yxiE - - T - - - Belongs to the universal stress protein A family
KGMEOLOC_03658 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KGMEOLOC_03659 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KGMEOLOC_03660 0.0 - - - L - - - HKD family nuclease
KGMEOLOC_03661 1.44e-86 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KGMEOLOC_03662 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
KGMEOLOC_03663 2.45e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
KGMEOLOC_03664 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
KGMEOLOC_03665 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KGMEOLOC_03666 1.41e-302 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
KGMEOLOC_03667 2.13e-228 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
KGMEOLOC_03668 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KGMEOLOC_03669 4.69e-298 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
KGMEOLOC_03670 4.04e-265 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KGMEOLOC_03671 4.09e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KGMEOLOC_03672 6.05e-222 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KGMEOLOC_03673 1.4e-194 yxeH - - S - - - hydrolases of the HAD superfamily
KGMEOLOC_03676 2.06e-42 yxeE - - - - - - -
KGMEOLOC_03677 5.09e-35 yxeD - - - - - - -
KGMEOLOC_03678 1.34e-20 - - - - - - - -
KGMEOLOC_03680 4.49e-232 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
KGMEOLOC_03681 1.55e-72 - - - L - - - COG2963 Transposase and inactivated derivatives
KGMEOLOC_03682 1.96e-150 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
KGMEOLOC_03683 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
KGMEOLOC_03684 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
KGMEOLOC_03685 3.28e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KGMEOLOC_03686 6.81e-225 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KGMEOLOC_03687 1.59e-124 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGMEOLOC_03688 9.05e-19 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGMEOLOC_03689 0.0 - - - T - - - Histidine kinase
KGMEOLOC_03690 6.65e-178 yvrH - - T - - - Transcriptional regulator
KGMEOLOC_03691 3.2e-212 - - - V ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KGMEOLOC_03692 1.36e-167 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 permease
KGMEOLOC_03693 1.89e-170 - - - S ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KGMEOLOC_03694 1.46e-206 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
KGMEOLOC_03695 8.8e-203 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
KGMEOLOC_03696 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
KGMEOLOC_03697 2.68e-252 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
KGMEOLOC_03698 3.29e-297 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
KGMEOLOC_03699 3.53e-227 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
KGMEOLOC_03700 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
KGMEOLOC_03701 2.92e-233 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
KGMEOLOC_03702 6.21e-203 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
KGMEOLOC_03703 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KGMEOLOC_03704 6.09e-175 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
KGMEOLOC_03705 1.43e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
KGMEOLOC_03706 1.1e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KGMEOLOC_03707 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
KGMEOLOC_03708 1.51e-195 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KGMEOLOC_03709 7.82e-134 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KGMEOLOC_03710 3.03e-257 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KGMEOLOC_03711 3.84e-259 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
KGMEOLOC_03712 2.61e-282 yxbF - - K - - - Bacterial regulatory proteins, tetR family
KGMEOLOC_03713 0.0 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KGMEOLOC_03714 8.79e-192 yxaL - - S - - - PQQ-like domain
KGMEOLOC_03715 3.04e-86 - - - S - - - Family of unknown function (DUF5391)
KGMEOLOC_03716 1.21e-67 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KGMEOLOC_03717 1.07e-262 - - - EGP - - - Major Facilitator Superfamily
KGMEOLOC_03718 2.33e-98 yxaI - - S - - - membrane protein domain
KGMEOLOC_03719 5.06e-167 - - - E - - - Ring-cleavage extradiol dioxygenase
KGMEOLOC_03720 1.61e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
KGMEOLOC_03721 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
KGMEOLOC_03722 1.44e-294 - - - S - - - Fic/DOC family
KGMEOLOC_03723 5.26e-314 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
KGMEOLOC_03724 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
KGMEOLOC_03725 4.71e-112 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
KGMEOLOC_03726 9.17e-205 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
KGMEOLOC_03727 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
KGMEOLOC_03728 7.31e-126 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
KGMEOLOC_03729 8.91e-248 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KGMEOLOC_03730 1.81e-235 - - - S - - - Fusaric acid resistance protein-like
KGMEOLOC_03732 5.15e-08 - - - L - - - resolvase
KGMEOLOC_03734 0.0 - - - L - - - ATPase involved in DNA repair
KGMEOLOC_03735 9.72e-11 - - - - - - - -
KGMEOLOC_03736 1.72e-305 - - - T - - - Putative serine esterase (DUF676)
KGMEOLOC_03737 1.91e-241 - - - - - - - -
KGMEOLOC_03738 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KGMEOLOC_03741 1.65e-286 yycP - - - - - - -
KGMEOLOC_03742 8.65e-174 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KGMEOLOC_03743 3.31e-237 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
KGMEOLOC_03744 4.31e-115 yycN - - K - - - Acetyltransferase
KGMEOLOC_03746 1.47e-265 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
KGMEOLOC_03747 1.86e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
KGMEOLOC_03748 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KGMEOLOC_03749 6.09e-296 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
KGMEOLOC_03750 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KGMEOLOC_03751 4.53e-189 - 1.14.11.27 - P ko:K10277 - ko00000,ko01000,ko03036 peptidyl-arginine hydroxylation
KGMEOLOC_03752 0.0 - - - S - - - ABC transporter
KGMEOLOC_03753 1.29e-176 - - - S - - - Major Facilitator Superfamily
KGMEOLOC_03754 0.0 - - - - - - - -
KGMEOLOC_03755 3.19e-248 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
KGMEOLOC_03756 0.0 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
KGMEOLOC_03757 8.72e-15 phoP1 - - KT ko:K02483 - ko00000,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGMEOLOC_03758 4.87e-280 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KGMEOLOC_03759 9.84e-192 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
KGMEOLOC_03760 1.77e-197 yycI - - S - - - protein conserved in bacteria
KGMEOLOC_03761 0.0 yycH - - S - - - protein conserved in bacteria
KGMEOLOC_03762 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KGMEOLOC_03763 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGMEOLOC_03768 1.06e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KGMEOLOC_03769 4.87e-98 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KGMEOLOC_03770 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
KGMEOLOC_03771 1.88e-39 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
KGMEOLOC_03773 3.6e-25 yycC - - K - - - YycC-like protein
KGMEOLOC_03774 7.2e-56 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase activity
KGMEOLOC_03775 1.55e-315 - - - M - - - Glycosyltransferase Family 4
KGMEOLOC_03776 1.2e-263 - - - S - - - Ecdysteroid kinase
KGMEOLOC_03777 2.05e-300 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
KGMEOLOC_03778 0.0 - - - M - - - Glycosyltransferase Family 4
KGMEOLOC_03779 1.85e-158 - - - S - - - GlcNAc-PI de-N-acetylase
KGMEOLOC_03780 1.99e-165 - - - KLT - - - COG0515 Serine threonine protein kinase
KGMEOLOC_03781 1.58e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
KGMEOLOC_03782 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
KGMEOLOC_03783 3.68e-206 yybS - - S - - - membrane
KGMEOLOC_03785 1.88e-111 cotF - - M ko:K06329 - ko00000 Spore coat protein
KGMEOLOC_03786 4.56e-87 yybR - - K - - - Transcriptional regulator
KGMEOLOC_03787 2.95e-211 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
KGMEOLOC_03788 2.14e-199 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KGMEOLOC_03789 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
KGMEOLOC_03790 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
KGMEOLOC_03791 4.15e-153 - - - K - - - FCD domain
KGMEOLOC_03792 5.75e-119 - - - S - - - PFAM DinB family protein
KGMEOLOC_03793 5.5e-209 - - - G - - - Major Facilitator Superfamily
KGMEOLOC_03794 4.47e-22 - - - G - - - Major Facilitator Superfamily
KGMEOLOC_03795 4.38e-209 - - - K - - - LysR substrate binding domain
KGMEOLOC_03796 1.13e-129 - - - E - - - LysE type translocator
KGMEOLOC_03797 3.29e-279 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KGMEOLOC_03798 9.22e-213 yybE - - K - - - Transcriptional regulator
KGMEOLOC_03799 9.61e-75 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
KGMEOLOC_03800 1.7e-148 ydgI - - C - - - nitroreductase
KGMEOLOC_03801 8.26e-91 - - - K - - - Winged helix DNA-binding domain
KGMEOLOC_03802 3.4e-197 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KGMEOLOC_03803 3.2e-100 yybA - - K - - - transcriptional
KGMEOLOC_03804 6.58e-101 yjcF - - S - - - Acetyltransferase (GNAT) domain
KGMEOLOC_03805 2.02e-212 - - - M - - - Domain of Unknown Function (DUF1259)
KGMEOLOC_03806 7.04e-89 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
KGMEOLOC_03807 6.24e-214 - - - K - - - Transcriptional regulator
KGMEOLOC_03808 3.96e-184 bdh 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KGMEOLOC_03809 7.43e-130 - - - - - - - -
KGMEOLOC_03810 9.78e-38 yyaL - - O ko:K06888 - ko00000 Highly conserved protein containing a thioredoxin domain
KGMEOLOC_03811 1.02e-106 - - - - - - - -
KGMEOLOC_03812 5.52e-92 ynaF - - - - - - -
KGMEOLOC_03814 2.83e-121 - 2.7.11.1 - KLT ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
KGMEOLOC_03815 4.88e-183 - 2.7.11.1 - KLT ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
KGMEOLOC_03816 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
KGMEOLOC_03817 7.58e-213 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
KGMEOLOC_03818 0.0 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
KGMEOLOC_03819 5.93e-89 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KGMEOLOC_03820 1.19e-232 ccpB - - K - - - Transcriptional regulator
KGMEOLOC_03821 1.52e-189 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
KGMEOLOC_03822 1.55e-133 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KGMEOLOC_03823 4.09e-142 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
KGMEOLOC_03824 1.11e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KGMEOLOC_03825 4.77e-99 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KGMEOLOC_03826 2.9e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
KGMEOLOC_03827 2.3e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KGMEOLOC_03828 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KGMEOLOC_03829 3.13e-46 yyzM - - S - - - protein conserved in bacteria
KGMEOLOC_03830 1.67e-225 yyaD - - S - - - Membrane
KGMEOLOC_03831 1.86e-114 yhhY - - K - - - FR47-like protein
KGMEOLOC_03832 4.91e-144 yyaC - - S - - - Sporulation protein YyaC
KGMEOLOC_03833 1.23e-190 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KGMEOLOC_03834 1.23e-172 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
KGMEOLOC_03835 6.61e-195 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
KGMEOLOC_03836 1.68e-166 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
KGMEOLOC_03837 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KGMEOLOC_03838 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KGMEOLOC_03839 8.37e-145 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
KGMEOLOC_03840 2.12e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KGMEOLOC_03841 1.99e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KGMEOLOC_03842 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KGMEOLOC_03843 8.47e-264 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KGMEOLOC_03844 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
KGMEOLOC_03845 3.2e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KGMEOLOC_03846 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
KGMEOLOC_03847 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KGMEOLOC_03848 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KGMEOLOC_03849 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
KGMEOLOC_03852 3e-236 yaaC - - S - - - YaaC-like Protein
KGMEOLOC_03853 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KGMEOLOC_03854 0.0 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KGMEOLOC_03855 1.29e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KGMEOLOC_03856 4.94e-140 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KGMEOLOC_03857 1.59e-285 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KGMEOLOC_03858 4.55e-265 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
KGMEOLOC_03860 7.51e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
KGMEOLOC_03861 1.41e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
KGMEOLOC_03862 3.03e-279 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
KGMEOLOC_03863 1.05e-130 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
KGMEOLOC_03864 2.48e-111 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KGMEOLOC_03865 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KGMEOLOC_03866 2.41e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KGMEOLOC_03867 6e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KGMEOLOC_03868 5.4e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
KGMEOLOC_03869 6.44e-50 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
KGMEOLOC_03870 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)