ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MIIHFEKM_00001 0.0 gltX 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MIIHFEKM_00004 0.0 - - - S - - - Calcineurin-like phosphoesterase
MIIHFEKM_00005 1.96e-186 ltbR - - K - - - Transcriptional regulator, IclR family, C-terminal domain protein
MIIHFEKM_00006 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIIHFEKM_00007 8.41e-165 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIIHFEKM_00008 5.98e-55 - - - K - - - Lrp/AsnC ligand binding domain
MIIHFEKM_00009 0.0 nox - - C - - - Pyridine nucleotide-disulphide oxidoreductase
MIIHFEKM_00010 4.71e-316 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MIIHFEKM_00011 1.57e-202 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
MIIHFEKM_00012 1.02e-202 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
MIIHFEKM_00013 2.54e-278 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MIIHFEKM_00015 3.07e-178 - - - S - - - Domain of unknown function (DUF4854)
MIIHFEKM_00016 1.65e-236 - - - S - - - CAAX protease self-immunity
MIIHFEKM_00017 2.29e-186 - - - M - - - Mechanosensitive ion channel
MIIHFEKM_00018 9.92e-149 - - - K - - - Bacterial regulatory proteins, tetR family
MIIHFEKM_00019 5.91e-297 - - - S - - - Psort location Cytoplasmic, score 8.87
MIIHFEKM_00020 1.12e-209 - - - S - - - Putative ABC-transporter type IV
MIIHFEKM_00021 1.27e-291 - 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Psort location Cytoplasmic, score 8.87
MIIHFEKM_00022 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
MIIHFEKM_00023 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
MIIHFEKM_00024 3.96e-253 - - - G - - - pfkB family carbohydrate kinase
MIIHFEKM_00025 3.36e-42 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
MIIHFEKM_00026 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 helicase superfamily c-terminal domain
MIIHFEKM_00027 0.0 - - - M - - - Spy0128-like isopeptide containing domain
MIIHFEKM_00028 1.17e-131 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Conserved hypothetical protein 95
MIIHFEKM_00029 1.47e-203 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MIIHFEKM_00030 7.44e-155 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MIIHFEKM_00031 4.08e-62 - - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
MIIHFEKM_00032 8.95e-94 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MIIHFEKM_00033 1.87e-212 lacZ 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
MIIHFEKM_00034 0.0 lacZ 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
MIIHFEKM_00035 8.36e-283 - - - S - - - Endonuclease/Exonuclease/phosphatase family
MIIHFEKM_00036 1.62e-205 - - - P - - - Cation efflux family
MIIHFEKM_00037 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MIIHFEKM_00038 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MIIHFEKM_00039 0.0 yjjK - - S ko:K15738 - ko00000,ko02000 ABC transporter
MIIHFEKM_00040 6.62e-176 - 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase C26
MIIHFEKM_00041 1.08e-119 ilvN 2.2.1.6 - E ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
MIIHFEKM_00042 0.0 ilvB 2.2.1.6 - H ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, central domain
MIIHFEKM_00043 3.18e-181 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MIIHFEKM_00044 4.3e-40 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MIIHFEKM_00045 1.08e-144 - - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
MIIHFEKM_00046 1.03e-156 - - - - - - - -
MIIHFEKM_00047 2.39e-113 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MIIHFEKM_00048 2.64e-67 - - - S - - - Protein of unknown function (DUF3039)
MIIHFEKM_00049 1.73e-248 - - - C ko:K19265 - ko00000,ko01000 Aldo/keto reductase family
MIIHFEKM_00050 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MIIHFEKM_00051 8.13e-59 - - - - - - - -
MIIHFEKM_00052 1.69e-174 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MIIHFEKM_00053 2.59e-170 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MIIHFEKM_00054 2.98e-313 - - - V ko:K12554 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Psort location Cytoplasmic, score 8.87
MIIHFEKM_00055 3.86e-236 - - - S ko:K07088 - ko00000 Auxin Efflux Carrier
MIIHFEKM_00058 4.94e-287 manC 2.7.7.13 - M ko:K00971 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Mannose-6-phosphate isomerase
MIIHFEKM_00059 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MIIHFEKM_00060 1.67e-79 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MIIHFEKM_00061 3.61e-175 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MIIHFEKM_00062 5.07e-185 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MIIHFEKM_00063 1.28e-229 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MIIHFEKM_00064 0.0 - - - V - - - Efflux ABC transporter, permease protein
MIIHFEKM_00065 3.25e-155 - - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
MIIHFEKM_00066 5.31e-295 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
MIIHFEKM_00067 0.0 rne 3.1.26.12 - J ko:K08300,ko:K08301 ko03018,map03018 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Ribonuclease E/G family
MIIHFEKM_00068 7.1e-62 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MIIHFEKM_00069 1.23e-52 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L27 protein
MIIHFEKM_00070 0.0 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MIIHFEKM_00071 1.76e-261 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MIIHFEKM_00072 2.39e-295 aspC 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K10907,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 DegT/DnrJ/EryC1/StrS aminotransferase family
MIIHFEKM_00074 5.51e-46 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MIIHFEKM_00075 3.74e-204 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MIIHFEKM_00076 3.53e-92 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MIIHFEKM_00077 2.3e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MIIHFEKM_00078 8.38e-188 - - - QT - - - PucR C-terminal helix-turn-helix domain
MIIHFEKM_00079 2.36e-216 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
MIIHFEKM_00080 4.06e-134 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
MIIHFEKM_00081 0.0 accC 6.3.4.14, 6.4.1.2, 6.4.1.3 - I ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase L chain, ATP binding domain protein
MIIHFEKM_00082 0.0 pccB - - I - - - Carboxyl transferase domain
MIIHFEKM_00083 0.0 fas - - I ko:K11533 ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931 ko00000,ko00001,ko00002,ko01000,ko01004 Beta-ketoacyl synthase, C-terminal domain
MIIHFEKM_00084 1.39e-102 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MIIHFEKM_00086 4.41e-156 - - - - - - - -
MIIHFEKM_00087 2.28e-238 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MIIHFEKM_00088 2.28e-65 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MIIHFEKM_00089 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MIIHFEKM_00090 2.65e-128 lemA - - S ko:K03744 - ko00000 LemA family
MIIHFEKM_00091 0.0 - - - S - - - Predicted membrane protein (DUF2207)
MIIHFEKM_00092 2.7e-237 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIIHFEKM_00093 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIIHFEKM_00094 2.38e-100 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
MIIHFEKM_00095 7.35e-28 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
MIIHFEKM_00096 5.57e-214 - - - C - - - Oxidoreductase, aldo keto reductase family protein
MIIHFEKM_00097 0.0 - - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase family U32 C-terminal domain
MIIHFEKM_00098 1.79e-288 yfiH - - Q ko:K05810 - ko00000,ko01000 Multi-copper polyphenol oxidoreductase laccase
MIIHFEKM_00099 3.41e-193 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MIIHFEKM_00100 2.7e-172 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MIIHFEKM_00101 3.73e-192 - - - D - - - nuclear chromosome segregation
MIIHFEKM_00102 0.0 pepC2 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MIIHFEKM_00103 8.35e-279 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MIIHFEKM_00104 0.0 - - - I - - - Psort location CytoplasmicMembrane, score 9.99
MIIHFEKM_00105 1.15e-305 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MIIHFEKM_00106 2.15e-155 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MIIHFEKM_00107 1.85e-280 phoR 2.7.13.3 - T ko:K07636,ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
MIIHFEKM_00108 1.32e-168 regX3 - - KT ko:K07776 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
MIIHFEKM_00109 3.8e-262 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import
MIIHFEKM_00110 2.63e-218 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MIIHFEKM_00111 1.53e-221 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
MIIHFEKM_00112 1.51e-188 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MIIHFEKM_00113 0.0 - - - S ko:K06901 - ko00000,ko02000 Permease family
MIIHFEKM_00114 2.41e-210 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
MIIHFEKM_00115 2.13e-114 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MIIHFEKM_00116 9.38e-68 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MIIHFEKM_00117 0.0 - - - T - - - Forkhead associated domain
MIIHFEKM_00118 0.0 - - - L - - - Superfamily I DNA and RNA helicases and helicase subunits
MIIHFEKM_00119 2.19e-52 - - - - - - - -
MIIHFEKM_00120 8.73e-132 - - - NO - - - SAF
MIIHFEKM_00121 1.76e-43 - - - S - - - Putative regulatory protein
MIIHFEKM_00122 1.84e-177 ygfA 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 5-formyltetrahydrofolate cyclo-ligase family
MIIHFEKM_00123 1.59e-103 rimJ 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MIIHFEKM_00124 1.73e-257 - - - - - - - -
MIIHFEKM_00125 4.55e-64 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MIIHFEKM_00129 2.06e-35 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L33
MIIHFEKM_00130 2.74e-302 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
MIIHFEKM_00131 0.0 - - - E ko:K03294 - ko00000 aromatic amino acid transport protein AroP K03293
MIIHFEKM_00132 4.15e-80 fdxA - - C ko:K05524 - ko00000 4Fe-4S binding domain
MIIHFEKM_00133 7.49e-282 dapC - - E - - - Aminotransferase class I and II
MIIHFEKM_00134 0.0 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MIIHFEKM_00136 1e-243 pdxB - - EH - - - Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIIHFEKM_00137 3.01e-147 yigZ - - S - - - Uncharacterized protein family UPF0029
MIIHFEKM_00138 1.73e-157 - - - - - - - -
MIIHFEKM_00139 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
MIIHFEKM_00140 1.31e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MIIHFEKM_00141 6.69e-97 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MIIHFEKM_00142 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
MIIHFEKM_00143 1.65e-267 - - - GK - - - transcriptional repressor of nag (N-acetylglucosamine) operon K02565
MIIHFEKM_00144 0.0 adhE 1.1.1.1, 1.2.1.10, 1.2.1.81 - C ko:K04072,ko:K15515 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MIIHFEKM_00145 3.9e-244 - - - K - - - Psort location Cytoplasmic, score
MIIHFEKM_00146 3.06e-198 - - - S - - - YwiC-like protein
MIIHFEKM_00147 6.58e-68 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MIIHFEKM_00148 1.06e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MIIHFEKM_00149 3.41e-151 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MIIHFEKM_00150 1.79e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MIIHFEKM_00151 2.32e-196 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MIIHFEKM_00152 6.95e-63 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MIIHFEKM_00153 2.68e-75 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MIIHFEKM_00154 2.32e-176 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MIIHFEKM_00155 1.15e-99 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MIIHFEKM_00156 5.27e-49 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MIIHFEKM_00157 7.84e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MIIHFEKM_00158 5.15e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MIIHFEKM_00159 4.44e-68 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MIIHFEKM_00160 1.94e-136 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MIIHFEKM_00161 4.97e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MIIHFEKM_00162 9.65e-91 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MIIHFEKM_00163 6.61e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MIIHFEKM_00164 5.96e-77 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MIIHFEKM_00165 6.25e-132 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MIIHFEKM_00166 1.75e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30p/L7e
MIIHFEKM_00167 3.98e-100 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MIIHFEKM_00168 0.0 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MIIHFEKM_00169 4.41e-131 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MIIHFEKM_00170 4.86e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MIIHFEKM_00171 1.03e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MIIHFEKM_00172 1.17e-81 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MIIHFEKM_00173 1.73e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MIIHFEKM_00174 1.4e-236 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIIHFEKM_00175 1.16e-92 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MIIHFEKM_00176 6.34e-190 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MIIHFEKM_00178 5.94e-208 - - - - - - - -
MIIHFEKM_00179 6.28e-249 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MIIHFEKM_00180 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MIIHFEKM_00181 5.79e-122 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MIIHFEKM_00182 5.82e-250 truB 5.4.99.25 - J ko:K03177 - ko00000,ko01000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MIIHFEKM_00183 9.91e-302 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 riboflavin kinase
MIIHFEKM_00184 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MIIHFEKM_00185 1.12e-128 - - - - - - - -
MIIHFEKM_00186 5.05e-07 - - - S - - - Mitochondrial domain of unknown function (DUF1713)
MIIHFEKM_00187 2.05e-164 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MIIHFEKM_00188 7.54e-240 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MIIHFEKM_00190 2.27e-307 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MIIHFEKM_00191 1.69e-278 - - - I - - - Diacylglycerol kinase catalytic domain
MIIHFEKM_00192 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
MIIHFEKM_00193 0.0 - - - S ko:K06889 - ko00000 alpha beta
MIIHFEKM_00194 5.96e-146 - - - S - - - Protein of unknown function (DUF4125)
MIIHFEKM_00195 0.0 - - - S - - - Domain of unknown function (DUF4037)
MIIHFEKM_00196 8.64e-163 tcsR3 - - K - - - helix_turn_helix, Lux Regulon
MIIHFEKM_00197 0.0 tcsS3 - - KT - - - PspC domain
MIIHFEKM_00198 0.0 pspC - - KT - - - PspC domain
MIIHFEKM_00199 5.45e-146 - - - - - - - -
MIIHFEKM_00200 2.09e-286 metC1 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
MIIHFEKM_00201 2.38e-168 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
MIIHFEKM_00202 1.71e-38 - - - E - - - Cys/Met metabolism PLP-dependent enzyme
MIIHFEKM_00204 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MIIHFEKM_00205 1.71e-186 - - - - - - - -
MIIHFEKM_00206 0.0 - - - E - - - Phospholipase B
MIIHFEKM_00207 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MIIHFEKM_00208 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Amino acid permease
MIIHFEKM_00209 0.0 - - - E - - - Serine carboxypeptidase
MIIHFEKM_00210 0.0 - - - E - - - Amino acid permease
MIIHFEKM_00211 1.05e-101 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
MIIHFEKM_00212 2.91e-179 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MIIHFEKM_00213 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
MIIHFEKM_00214 1.62e-84 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
MIIHFEKM_00215 4.64e-159 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
MIIHFEKM_00216 0.0 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphomannose isomerase type I
MIIHFEKM_00217 2.41e-29 - - - - - - - -
MIIHFEKM_00218 1.87e-288 senX3 2.7.13.3 - T ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
MIIHFEKM_00219 4.13e-156 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
MIIHFEKM_00220 2.42e-268 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MIIHFEKM_00221 1.91e-228 - - - S - - - CHAP domain
MIIHFEKM_00222 1.42e-140 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
MIIHFEKM_00223 8.87e-252 - - - T - - - Universal stress protein family
MIIHFEKM_00224 1.07e-94 - - - O - - - OsmC-like protein
MIIHFEKM_00225 1.12e-223 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MIIHFEKM_00226 1.46e-170 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dihydrofolate reductase
MIIHFEKM_00227 1.04e-129 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 low molecular weight
MIIHFEKM_00228 9.11e-256 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MIIHFEKM_00229 5.36e-206 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MIIHFEKM_00231 3.21e-245 - - - S - - - DUF218 domain
MIIHFEKM_00232 1.78e-239 - 3.1.3.5 - S ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase
MIIHFEKM_00233 1.95e-139 - - - - - - - -
MIIHFEKM_00234 0.0 - - - L ko:K07459 - ko00000 AAA ATPase domain
MIIHFEKM_00236 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2130)
MIIHFEKM_00237 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
MIIHFEKM_00238 1.89e-187 - - - S - - - Domain of unknown function (DUF4194)
MIIHFEKM_00239 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
MIIHFEKM_00240 7.2e-302 - - - S - - - Psort location Cytoplasmic, score 8.87
MIIHFEKM_00242 2.83e-84 - - - K - - - Protein of unknown function, DUF488
MIIHFEKM_00243 0.0 gph - - G ko:K16209 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
MIIHFEKM_00244 0.0 lacZ6 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
MIIHFEKM_00245 3.44e-237 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
MIIHFEKM_00246 7.35e-152 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MIIHFEKM_00247 2.76e-80 - - - - - - - -
MIIHFEKM_00248 8.48e-132 - - - S - - - Domain of unknown function (DUF4190)
MIIHFEKM_00249 5.97e-106 - - - S - - - Domain of unknown function (DUF4190)
MIIHFEKM_00250 2.28e-260 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MIIHFEKM_00251 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
MIIHFEKM_00252 7.36e-225 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
MIIHFEKM_00253 4.97e-225 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MIIHFEKM_00254 2.41e-239 - - - K - - - Periplasmic binding protein domain
MIIHFEKM_00258 3.32e-240 - - - M - - - Glycosyltransferase like family 2
MIIHFEKM_00259 0.0 - - - S - - - AI-2E family transporter
MIIHFEKM_00260 2.55e-307 - - - M - - - Glycosyl transferase family 21
MIIHFEKM_00261 1.78e-207 natA - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MIIHFEKM_00262 0.0 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
MIIHFEKM_00263 8.49e-301 dacB 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-Ala-D-Ala carboxypeptidase 3 (S13) family
MIIHFEKM_00264 5e-274 tilS 2.4.2.8, 6.3.4.19 - J ko:K00760,ko:K04075 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MIIHFEKM_00265 2.77e-128 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MIIHFEKM_00266 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MIIHFEKM_00267 3.66e-186 folK 2.7.6.3, 4.1.2.25 - H ko:K13940 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MIIHFEKM_00268 7.39e-148 - - - S - - - Protein of unknown function (DUF3180)
MIIHFEKM_00269 4.03e-221 tesB - - I ko:K10805 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Thioesterase-like superfamily
MIIHFEKM_00270 0.0 yjjK - - S - - - ATP-binding cassette protein, ChvD family
MIIHFEKM_00271 4.14e-91 fms 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
MIIHFEKM_00272 0.0 - 2.5.1.49 - H ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 9.98
MIIHFEKM_00273 6.02e-145 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MIIHFEKM_00274 5.11e-184 - - - - - - - -
MIIHFEKM_00276 4.11e-223 - - - - - - - -
MIIHFEKM_00277 1.47e-47 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
MIIHFEKM_00278 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
MIIHFEKM_00279 0.0 - 3.2.1.37, 3.2.1.55 GH43,GH51 G ko:K01198,ko:K01209 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
MIIHFEKM_00280 2.63e-241 - - - K ko:K02529,ko:K17640 - ko00000,ko03000 Bacterial regulatory proteins, lacI family
MIIHFEKM_00281 1.02e-310 - - - G ko:K02027,ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter periplasmic binding protein YcjN precursor K02027
MIIHFEKM_00282 1.54e-246 - - - U ko:K02025,ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MIIHFEKM_00283 1.07e-203 - - - P ko:K02026,ko:K10119,ko:K17243 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MIIHFEKM_00284 0.0 - 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
MIIHFEKM_00285 0.0 - 3.1.1.53 - G ko:K05970 - ko00000,ko01000 Glycosyl hydrolase family 2, sugar binding domain protein
MIIHFEKM_00286 3.21e-299 - - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
MIIHFEKM_00287 0.0 - - - G - - - candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
MIIHFEKM_00288 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
MIIHFEKM_00289 8.6e-293 xylR - - GK - - - ROK family
MIIHFEKM_00290 9.15e-49 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
MIIHFEKM_00291 9.55e-217 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MIIHFEKM_00292 9.47e-225 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MIIHFEKM_00293 2.61e-150 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Belongs to the SUA5 family
MIIHFEKM_00294 1.04e-268 rfe 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 4
MIIHFEKM_00295 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MIIHFEKM_00296 1.09e-158 orn - - L ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
MIIHFEKM_00297 1.72e-200 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MIIHFEKM_00298 0.0 - - - L - - - PIF1-like helicase
MIIHFEKM_00299 7.39e-98 - - - - - - - -
MIIHFEKM_00300 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MIIHFEKM_00301 6.13e-174 - - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
MIIHFEKM_00302 0.0 pepO 3.4.24.11, 3.4.24.71 - O ko:K01389,ko:K01415,ko:K07386 ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Peptidase family M13
MIIHFEKM_00303 1.78e-133 - - - S - - - Short repeat of unknown function (DUF308)
MIIHFEKM_00304 1.86e-165 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
MIIHFEKM_00305 0.0 gltA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Citrate synthase, C-terminal domain
MIIHFEKM_00306 6.33e-109 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MIIHFEKM_00307 1.57e-236 dapD 2.3.1.117 - E ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
MIIHFEKM_00308 1.65e-265 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MIIHFEKM_00309 1.64e-298 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Cell division ATP-binding protein FtsE
MIIHFEKM_00310 2.42e-209 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in cellular division
MIIHFEKM_00311 3.74e-282 - - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain protein
MIIHFEKM_00312 1.36e-105 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MIIHFEKM_00313 3.92e-213 glnH - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter, substrate-binding protein, family 3
MIIHFEKM_00314 3.75e-215 glnH - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter, substrate-binding protein, family 3
MIIHFEKM_00315 6.2e-208 yecS - - E ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MIIHFEKM_00316 2.6e-197 tcyC 3.6.3.21 - E ko:K02028,ko:K02029 - ko00000,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MIIHFEKM_00317 2.66e-231 - - - K - - - Psort location Cytoplasmic, score
MIIHFEKM_00318 1.98e-164 - - - K - - - helix_turn_helix, Lux Regulon
MIIHFEKM_00319 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MIIHFEKM_00320 2.61e-184 - 5.4.99.28, 5.4.99.29 - J ko:K06177 - ko00000,ko01000,ko03009,ko03016 RNA pseudouridylate synthase
MIIHFEKM_00321 6.41e-89 - - - - - - - -
MIIHFEKM_00322 1.14e-175 coaX 2.7.1.33 - H ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MIIHFEKM_00323 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
MIIHFEKM_00324 7.86e-217 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MIIHFEKM_00325 8.71e-201 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MIIHFEKM_00326 4.99e-181 oppDF2 - - P ko:K02031,ko:K02032,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
MIIHFEKM_00327 9.13e-180 - - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
MIIHFEKM_00328 3.07e-284 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
MIIHFEKM_00329 5.12e-243 cbs 2.5.1.47, 4.2.1.22 - E ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
MIIHFEKM_00330 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MIIHFEKM_00331 1.01e-221 - - - S - - - Protein conserved in bacteria
MIIHFEKM_00332 1.29e-135 - - - J - - - Acetyltransferase (GNAT) domain
MIIHFEKM_00335 4.02e-52 - - - S - - - Protein of unknown function (DUF1706)
MIIHFEKM_00336 1.14e-30 M1-431 - - S - - - Protein of unknown function (DUF1706)
MIIHFEKM_00338 3.78e-76 - - - - - - - -
MIIHFEKM_00339 4.86e-84 - - - - - - - -
MIIHFEKM_00340 7.91e-95 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MIIHFEKM_00341 0.0 - - - KL - - - Domain of unknown function (DUF3427)
MIIHFEKM_00342 8.48e-81 - - - S - - - Fic/DOC family
MIIHFEKM_00343 0.0 - - - S - - - Protein of unknown function (DUF1524)
MIIHFEKM_00344 3.33e-123 - - - S - - - Protein of unknown function (DUF4065)
MIIHFEKM_00345 9.13e-119 - - - S ko:K07341 - ko00000,ko02048 Fic/DOC family
MIIHFEKM_00346 2.04e-114 - - - K - - - Acetyltransferase (GNAT) domain
MIIHFEKM_00347 5.05e-190 - - - S - - - 3-oxo-5-alpha-steroid 4-dehydrogenase
MIIHFEKM_00348 3.3e-290 gldA 1.1.1.6 - C ko:K00005,ko:K08317 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
MIIHFEKM_00349 8.52e-122 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MIIHFEKM_00350 1.21e-129 cysE - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MIIHFEKM_00351 0.0 alr 5.1.1.1 - M ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MIIHFEKM_00352 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MIIHFEKM_00353 6.68e-282 - - - P - - - Citrate transporter
MIIHFEKM_00355 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MIIHFEKM_00356 6.53e-111 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MIIHFEKM_00357 1.2e-286 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MIIHFEKM_00358 2.4e-93 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
MIIHFEKM_00359 0.0 lysX - - S - - - Uncharacterised conserved protein (DUF2156)
MIIHFEKM_00360 0.0 - - - S - - - Putative esterase
MIIHFEKM_00361 2.74e-305 purD 6.3.3.1, 6.3.4.13 - F ko:K01945,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MIIHFEKM_00362 3.44e-251 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MIIHFEKM_00363 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MIIHFEKM_00364 0.0 - - - L ko:K03502 - ko00000,ko03400 DNA-damage repair protein (DNA polymerase IV) K00961
MIIHFEKM_00365 7.52e-95 - - - - - - - -
MIIHFEKM_00366 9.81e-297 - - - S - - - 50S ribosome-binding GTPase
MIIHFEKM_00367 1.21e-130 - - - - - - - -
MIIHFEKM_00368 1.97e-116 - - - S ko:K07005 - ko00000 Pyridoxamine 5'-phosphate oxidase
MIIHFEKM_00369 1.97e-140 - - - K - - - sequence-specific DNA binding
MIIHFEKM_00371 0.0 - - - - - - - -
MIIHFEKM_00372 2.73e-162 - - - - - - - -
MIIHFEKM_00373 2.77e-90 - - - - - - - -
MIIHFEKM_00374 4.96e-139 - - - - - - - -
MIIHFEKM_00375 4.93e-286 - - - S - - - Short C-terminal domain
MIIHFEKM_00376 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 CobB/CobQ-like glutamine amidotransferase domain
MIIHFEKM_00377 4.83e-176 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MIIHFEKM_00378 8.01e-297 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MIIHFEKM_00379 3.4e-300 - - - M - - - Glycosyl transferase 4-like domain
MIIHFEKM_00380 2.78e-253 ltaE 4.1.2.48 - E ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Beta-eliminating lyase
MIIHFEKM_00382 8.2e-81 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MIIHFEKM_00383 1.34e-104 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MIIHFEKM_00384 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MIIHFEKM_00385 2.25e-294 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MIIHFEKM_00386 1.07e-157 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIIHFEKM_00387 8.01e-123 - - - - - - - -
MIIHFEKM_00388 7.02e-134 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MIIHFEKM_00389 1.34e-103 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MIIHFEKM_00390 6.95e-306 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
MIIHFEKM_00391 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase large chain, oligomerisation domain
MIIHFEKM_00392 5.67e-232 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MIIHFEKM_00393 6.35e-148 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MIIHFEKM_00394 0.0 ilvD 4.2.1.9 - H ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
MIIHFEKM_00395 4.74e-60 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MIIHFEKM_00396 8.72e-279 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MIIHFEKM_00397 0.0 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 Mycolic acid cyclopropane synthetase
MIIHFEKM_00398 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MIIHFEKM_00399 1.06e-235 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MIIHFEKM_00400 8.15e-110 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 haloacid dehalogenase-like hydrolase
MIIHFEKM_00401 5.9e-163 - - - S - - - SNARE associated Golgi protein
MIIHFEKM_00402 0.0 arc - - O ko:K13527 ko03050,map03050 ko00000,ko00001,ko00002,ko03051 AAA ATPase forming ring-shaped complexes
MIIHFEKM_00403 0.0 dop 3.5.1.119 - S ko:K20814 - ko00000,ko01000,ko03051 Pup-ligase protein
MIIHFEKM_00404 4.64e-220 - 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase family
MIIHFEKM_00405 8.24e-41 pup - - S ko:K13570 - ko00000,ko04121 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
MIIHFEKM_00406 0.0 pafA 6.3.1.19 - O ko:K13571 - ko00000,ko00002,ko01000,ko03051 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MIIHFEKM_00407 4.7e-57 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Belongs to the bacterial histone-like protein family
MIIHFEKM_00408 0.0 - - - S - - - Lysylphosphatidylglycerol synthase TM region
MIIHFEKM_00409 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase C-terminal
MIIHFEKM_00410 0.0 - - - S - - - PGAP1-like protein
MIIHFEKM_00412 1.09e-125 - - - - - - - -
MIIHFEKM_00413 1.23e-230 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
MIIHFEKM_00414 1.13e-249 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
MIIHFEKM_00415 9.9e-116 - - - - - - - -
MIIHFEKM_00416 1.98e-231 - - - S - - - Protein of unknown function DUF58
MIIHFEKM_00417 1.79e-246 moxR - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
MIIHFEKM_00418 1.57e-180 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MIIHFEKM_00419 9.65e-114 - - - S - - - LytR cell envelope-related transcriptional attenuator
MIIHFEKM_00420 4.22e-45 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
MIIHFEKM_00421 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MIIHFEKM_00422 2.56e-56 - - - S - - - Proteins of 100 residues with WXG
MIIHFEKM_00423 1.78e-202 - - - - - - - -
MIIHFEKM_00424 4.23e-171 phoP - - KT ko:K02483 - ko00000,ko02022 Response regulator receiver domain protein
MIIHFEKM_00425 0.0 phoR 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
MIIHFEKM_00426 1.15e-103 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
MIIHFEKM_00427 4.88e-266 - - - S - - - Protein of unknown function (DUF3027)
MIIHFEKM_00428 6.14e-178 - - - - - - - -
MIIHFEKM_00429 1.7e-234 uspA - - T - - - Belongs to the universal stress protein A family
MIIHFEKM_00430 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 ATPase family associated with various cellular activities (AAA)
MIIHFEKM_00431 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MIIHFEKM_00432 0.0 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Histidyl-tRNA synthetase
MIIHFEKM_00433 5.33e-294 - - - S - - - Domain of Unknown Function (DUF349)
MIIHFEKM_00434 1.4e-189 - - - S ko:K06889 - ko00000 Serine aminopeptidase, S33
MIIHFEKM_00435 1.1e-182 gluA - - E ko:K10008 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding protein of ABC transporter for glutamate K02028
MIIHFEKM_00436 1.51e-198 gluB - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MIIHFEKM_00437 2.23e-142 gluC - - E ko:K10006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MIIHFEKM_00438 1.1e-256 gluD - - E ko:K10007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MIIHFEKM_00439 1.25e-239 - - - S - - - Polyphosphate kinase 2 (PPK2)
MIIHFEKM_00440 0.0 - - - L - - - DEAD DEAH box helicase
MIIHFEKM_00441 0.0 rarA - - L ko:K07478 - ko00000 Recombination factor protein RarA
MIIHFEKM_00442 0.0 - - - EGP - - - Major Facilitator Superfamily
MIIHFEKM_00443 0.0 - 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
MIIHFEKM_00444 8.63e-255 - - - L - - - Transposase, Mutator family
MIIHFEKM_00446 0.0 - - - - - - - -
MIIHFEKM_00447 2.23e-184 - - - E - - - Psort location Cytoplasmic, score 8.87
MIIHFEKM_00448 1.42e-85 - - - S - - - Zincin-like metallopeptidase
MIIHFEKM_00449 1.17e-93 yccF - - S - - - Inner membrane component domain
MIIHFEKM_00450 7.88e-182 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MIIHFEKM_00451 1.9e-62 - - - J ko:K07574 - ko00000,ko03009 CRS1_YhbY
MIIHFEKM_00452 7.3e-210 - - - S - - - Aldo/keto reductase family
MIIHFEKM_00453 0.0 - - - GP ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MIIHFEKM_00454 2.94e-85 - - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MIIHFEKM_00455 1.93e-172 ppgK 2.7.1.2, 2.7.1.63 - GK ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
MIIHFEKM_00456 1.3e-283 - - - E - - - Aminotransferase class I and II
MIIHFEKM_00457 7.71e-193 - - - P ko:K16784 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MIIHFEKM_00458 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MIIHFEKM_00459 0.0 - - - S - - - Tetratricopeptide repeat
MIIHFEKM_00460 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MIIHFEKM_00461 5.3e-263 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MIIHFEKM_00462 3.49e-143 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MIIHFEKM_00463 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MIIHFEKM_00464 1.07e-188 - - - S - - - Domain of unknown function (DUF4191)
MIIHFEKM_00465 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIIHFEKM_00466 6.92e-134 - - - S - - - Protein of unknown function (DUF3043)
MIIHFEKM_00467 0.0 argE - - E - - - Peptidase dimerisation domain
MIIHFEKM_00468 7.53e-272 - - - T - - - Histidine kinase
MIIHFEKM_00469 1.03e-55 - - - - - - - -
MIIHFEKM_00470 6.74e-209 - - - V - - - N-Acetylmuramoyl-L-alanine amidase
MIIHFEKM_00471 1.05e-287 ytrE - - V ko:K02003,ko:K10038 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 lipoprotein transporter activity
MIIHFEKM_00472 2.66e-139 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MIIHFEKM_00473 0.0 ykoD - - P ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MIIHFEKM_00474 3.03e-169 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MIIHFEKM_00475 2.42e-288 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MIIHFEKM_00476 1.8e-18 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MIIHFEKM_00477 9.87e-217 tsnR - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIIHFEKM_00478 3.65e-251 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MIIHFEKM_00479 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Phenylalanyl-tRNA synthetase beta
MIIHFEKM_00480 5.69e-190 - - - - - - - -
MIIHFEKM_00481 1.64e-260 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MIIHFEKM_00482 7.16e-278 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MIIHFEKM_00483 5.02e-228 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
MIIHFEKM_00484 1.31e-305 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
MIIHFEKM_00485 5.7e-235 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MIIHFEKM_00486 1.23e-119 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MIIHFEKM_00487 8.47e-304 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MIIHFEKM_00488 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
MIIHFEKM_00489 2.15e-198 butA 1.1.1.100, 1.1.1.304, 1.1.1.76 - IQ ko:K00059,ko:K03366 ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00650,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MIIHFEKM_00490 3.62e-116 - - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MIIHFEKM_00491 0.0 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MIIHFEKM_00492 2.75e-261 - - - L - - - Tetratricopeptide repeat
MIIHFEKM_00493 4.09e-248 - - - G - - - Haloacid dehalogenase-like hydrolase
MIIHFEKM_00494 8.69e-185 tlyA 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
MIIHFEKM_00495 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
MIIHFEKM_00496 9.59e-152 trkA - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
MIIHFEKM_00497 8.73e-236 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MIIHFEKM_00498 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MIIHFEKM_00499 3.85e-166 - - - S - - - Haloacid dehalogenase-like hydrolase
MIIHFEKM_00500 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase N terminus
MIIHFEKM_00501 4.6e-307 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MIIHFEKM_00502 3.59e-148 - - - - - - - -
MIIHFEKM_00503 1.06e-171 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MIIHFEKM_00504 2.27e-246 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MIIHFEKM_00506 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MIIHFEKM_00507 4.35e-94 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MIIHFEKM_00508 6.21e-159 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
MIIHFEKM_00509 3.21e-134 - - - - - - - -
MIIHFEKM_00512 9.97e-94 pdxH - - S ko:K07006 - ko00000 Pfam:Pyridox_oxidase
MIIHFEKM_00513 1.72e-206 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
MIIHFEKM_00514 5.76e-217 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MIIHFEKM_00515 5.23e-213 - - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MIIHFEKM_00516 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MIIHFEKM_00517 2.36e-171 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Helix-hairpin-helix motif
MIIHFEKM_00518 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein
MIIHFEKM_00519 2.44e-239 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MIIHFEKM_00520 1.84e-146 tsaE - - S ko:K06925 - ko00000,ko03016 Threonylcarbamoyl adenosine biosynthesis protein TsaE
MIIHFEKM_00521 7.23e-202 yeaZ - - O ko:K14742 - ko00000,ko03016 Glycoprotease family
MIIHFEKM_00522 3.49e-118 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 FR47-like protein
MIIHFEKM_00523 7.97e-251 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MIIHFEKM_00525 1.79e-117 - - - - - - - -
MIIHFEKM_00527 1.16e-81 - - - - - - - -
MIIHFEKM_00528 1.13e-137 - - - M - - - Peptidase family M23
MIIHFEKM_00529 0.0 - - - G - - - ABC transporter substrate-binding protein
MIIHFEKM_00530 1.2e-305 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the isocitrate and isopropylmalate dehydrogenases family
MIIHFEKM_00531 2.97e-266 guaB3 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 IMP dehydrogenase family protein
MIIHFEKM_00533 0.0 fadD3 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 long-chain-fatty acid CoA ligase
MIIHFEKM_00534 5.55e-111 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MIIHFEKM_00535 1.03e-208 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MIIHFEKM_00536 2.5e-177 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MIIHFEKM_00537 5.41e-172 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MIIHFEKM_00538 1.16e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MIIHFEKM_00539 5.59e-226 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Cytidylyltransferase family
MIIHFEKM_00540 3.81e-294 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MIIHFEKM_00541 7.65e-136 - - - K - - - WHG domain
MIIHFEKM_00542 3.54e-149 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MIIHFEKM_00543 4.44e-173 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MIIHFEKM_00544 2.11e-178 hisF 4.1.3.27 - E ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MIIHFEKM_00545 6.65e-100 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MIIHFEKM_00546 0.0 trpE 4.1.3.27 - E ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MIIHFEKM_00547 4.39e-148 - - - L - - - Uracil DNA glycosylase superfamily
MIIHFEKM_00548 3.13e-11 - - - - - - - -
MIIHFEKM_00549 0.00074 - - - - - - - -
MIIHFEKM_00550 0.0 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MIIHFEKM_00551 3.55e-206 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MIIHFEKM_00552 4.78e-235 lgt - - M - - - Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MIIHFEKM_00553 2.68e-157 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribulose-phosphate 3-epimerase
MIIHFEKM_00554 3.18e-55 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoribosyl-ATP pyrophosphohydrolase
MIIHFEKM_00555 5.79e-201 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 ATP phosphoribosyltransferase
MIIHFEKM_00556 4.93e-141 pgsA2 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIIHFEKM_00557 2.38e-225 - - - S - - - Bacterial protein of unknown function (DUF881)
MIIHFEKM_00558 1.09e-63 sbp - - S - - - Protein of unknown function (DUF1290)
MIIHFEKM_00559 1.81e-197 - - - S - - - Bacterial protein of unknown function (DUF881)
MIIHFEKM_00560 2.66e-97 garA - - T - - - Inner membrane component of T3SS, cytoplasmic domain
MIIHFEKM_00561 2.48e-170 merR2 - - K - - - helix_turn_helix, mercury resistance
MIIHFEKM_00562 5.12e-91 - - - - - - - -
MIIHFEKM_00563 3.58e-85 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIIHFEKM_00564 5e-88 - - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIIHFEKM_00565 2.61e-179 nt5e 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD-hyrolase-like
MIIHFEKM_00566 5.49e-82 rbpA - - K - - - Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
MIIHFEKM_00567 0.0 helY - - L ko:K03727 - ko00000,ko01000 DEAD DEAH box helicase
MIIHFEKM_00568 2.35e-67 - - - - - - - -
MIIHFEKM_00569 0.0 - - - K - - - WYL domain
MIIHFEKM_00570 0.0 ugp 2.7.7.9 - G ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MIIHFEKM_00572 0.0 der - - F ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MIIHFEKM_00573 7.04e-186 rluB 5.4.99.19, 5.4.99.22 - J ko:K06178,ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MIIHFEKM_00574 3.45e-221 - - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MIIHFEKM_00575 5.52e-37 - - - - - - - -
MIIHFEKM_00576 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MIIHFEKM_00577 0.0 - - - - - - - -
MIIHFEKM_00578 1.85e-212 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MIIHFEKM_00579 5.72e-283 sucC 6.2.1.5 - F ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MIIHFEKM_00580 2.2e-133 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MIIHFEKM_00581 1.9e-72 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit
MIIHFEKM_00582 1.2e-260 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MIIHFEKM_00583 5.91e-141 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MIIHFEKM_00584 6.75e-132 ruvC 3.1.22.4 - L ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MIIHFEKM_00585 6.09e-175 yebC - - K - - - transcriptional regulatory protein
MIIHFEKM_00586 1.34e-240 pimA 2.4.1.345 GT4 M ko:K08256 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MIIHFEKM_00587 4.4e-247 htrB 2.3.1.265 - M ko:K22311 - ko00000,ko01000 Bacterial lipid A biosynthesis acyltransferase
MIIHFEKM_00588 8.83e-151 pgsA1 2.7.8.11, 2.7.8.5 - I ko:K00995,ko:K00999 ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070 ko00000,ko00001,ko01000 CDP-alcohol phosphatidyltransferase
MIIHFEKM_00589 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MIIHFEKM_00590 3.74e-127 - - - S - - - ATPases associated with a variety of cellular activities
MIIHFEKM_00592 5.2e-123 - 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MIIHFEKM_00593 2.65e-32 - - - - - - - -
MIIHFEKM_00599 4.49e-199 - - - S - - - PAC2 family
MIIHFEKM_00600 1.67e-191 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MIIHFEKM_00601 2.17e-204 - - - G - - - Fructosamine kinase
MIIHFEKM_00602 2.49e-279 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MIIHFEKM_00603 2.8e-256 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MIIHFEKM_00604 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the transketolase family
MIIHFEKM_00605 9.8e-258 tal 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MIIHFEKM_00606 3.06e-109 - - - S - - - PFAM Pentapeptide repeats (8 copies)
MIIHFEKM_00607 4.1e-293 - 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K00841,ko:K08969,ko:K10907,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
MIIHFEKM_00608 1.01e-117 - - - K - - - helix_turn_helix ASNC type
MIIHFEKM_00609 0.0 aspC 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K10907,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase, class I II
MIIHFEKM_00610 7.54e-207 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MIIHFEKM_00611 2.87e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase SecG subunit
MIIHFEKM_00612 2.06e-194 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MIIHFEKM_00613 2.34e-284 pgk 2.7.2.3, 5.3.1.1 - F ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Phosphoglycerate kinase
MIIHFEKM_00614 2.67e-224 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MIIHFEKM_00615 1.72e-224 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MIIHFEKM_00616 1.28e-225 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Shikimate dehydrogenase substrate binding domain
MIIHFEKM_00617 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MIIHFEKM_00618 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MIIHFEKM_00620 2.31e-230 - - - - - - - -
MIIHFEKM_00621 1.57e-127 nnrE - - L - - - Uracil DNA glycosylase superfamily
MIIHFEKM_00622 1.93e-157 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
MIIHFEKM_00623 0.0 ybiT - - S ko:K06158 - ko00000,ko03012 ABC transporter
MIIHFEKM_00624 3.78e-249 - - - P - - - Cation efflux family
MIIHFEKM_00625 3.09e-187 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MIIHFEKM_00626 2.09e-236 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MIIHFEKM_00627 0.0 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MIIHFEKM_00628 5e-140 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
MIIHFEKM_00629 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
MIIHFEKM_00630 7.4e-223 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
MIIHFEKM_00631 5.22e-158 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MIIHFEKM_00632 1.23e-243 - - - S - - - Protein conserved in bacteria
MIIHFEKM_00633 9.71e-232 - - - O - - - ADP-ribosylglycohydrolase
MIIHFEKM_00634 1.2e-76 - - - K - - - HxlR-like helix-turn-helix
MIIHFEKM_00635 1.25e-66 - - - L - - - NUDIX domain
MIIHFEKM_00636 6.8e-104 ypeA 2.3.1.1 - K ko:K22477 ko00220,ko01210,ko01230,map00220,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.87
MIIHFEKM_00637 5.35e-160 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MIIHFEKM_00638 8.93e-241 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MIIHFEKM_00639 3.32e-202 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
MIIHFEKM_00640 1.68e-225 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the OMP decarboxylase family. Type 2 subfamily
MIIHFEKM_00641 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MIIHFEKM_00642 1.83e-96 pyrI - - F ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002 Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
MIIHFEKM_00643 6.91e-242 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MIIHFEKM_00644 1.33e-115 - - - S - - - Domain of unknown function (DUF4186)
MIIHFEKM_00645 0.0 glnE 2.7.7.42, 2.7.7.89 - H ko:K00982 - ko00000,ko01000 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
MIIHFEKM_00646 7.7e-205 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
MIIHFEKM_00647 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MIIHFEKM_00648 1.07e-127 sixA - - T ko:K08296 - ko00000,ko01000 Phosphoglycerate mutase family
MIIHFEKM_00649 7.41e-254 trmI 2.1.1.219, 2.1.1.220 - J ko:K07442 - ko00000,ko01000,ko03016 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MIIHFEKM_00650 1.41e-203 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MIIHFEKM_00651 2.02e-311 glgA 2.4.1.342 GT4 G ko:K16148 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000,ko01003 Starch synthase catalytic domain
MIIHFEKM_00652 4.8e-114 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Redoxin
MIIHFEKM_00653 1.11e-103 - - - - - - - -
MIIHFEKM_00654 0.0 gltD 1.4.1.13, 1.4.1.14 - C ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MIIHFEKM_00655 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase NADPH large subunit
MIIHFEKM_00656 0.0 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
MIIHFEKM_00657 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MIIHFEKM_00658 1.36e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MIIHFEKM_00659 1.74e-179 - - - S - - - UPF0126 domain
MIIHFEKM_00660 2.14e-289 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Amino-transferase class IV
MIIHFEKM_00661 6.37e-139 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MIIHFEKM_00662 2.54e-249 - - - S ko:K06889 - ko00000 alpha beta
MIIHFEKM_00663 0.0 pntB 1.6.1.2 - C ko:K00325 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MIIHFEKM_00664 4.73e-62 pntAB 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 4TM region of pyridine nucleotide transhydrogenase, mitoch
MIIHFEKM_00665 2.51e-258 pntA 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 NAD(P) transhydrogenase subunit alpha part 1 K00324
MIIHFEKM_00666 0.0 fadD2 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
MIIHFEKM_00667 6.02e-232 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MIIHFEKM_00668 0.0 corC - - S - - - CBS domain
MIIHFEKM_00669 1.5e-134 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MIIHFEKM_00670 1.28e-274 phoH - - T ko:K06217 - ko00000 PhoH-like protein
MIIHFEKM_00671 2.19e-77 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
MIIHFEKM_00672 7.71e-185 - 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MIIHFEKM_00674 2.75e-211 spoU2 - - J - - - SpoU rRNA Methylase family
MIIHFEKM_00675 9.8e-171 tnp3503b - - L - - - Transposase and inactivated derivatives
MIIHFEKM_00676 2.43e-284 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MIIHFEKM_00677 5.86e-121 - - - S - - - Iron-sulfur cluster assembly protein
MIIHFEKM_00678 3.17e-135 iscU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
MIIHFEKM_00679 2.17e-305 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MIIHFEKM_00680 8.04e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
MIIHFEKM_00681 8.08e-300 sufD - - O ko:K09015 - ko00000 FeS assembly protein SufD
MIIHFEKM_00682 0.0 sufB - - O ko:K09014 - ko00000 FeS assembly protein SufB
MIIHFEKM_00683 0.0 - - - S - - - L,D-transpeptidase catalytic domain
MIIHFEKM_00684 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MIIHFEKM_00685 3.78e-73 - 3.2.1.1, 3.2.1.41 CBM48,GH13 M ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 Aamy_C
MIIHFEKM_00686 4.16e-236 pulA 3.2.1.41, 3.2.1.68 CBM48,GH13 G ko:K01200,ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
MIIHFEKM_00687 2.25e-109 - 3.2.1.1, 3.2.1.41 CBM48,GH13 M ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 Aamy_C
MIIHFEKM_00688 7.78e-125 - 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
MIIHFEKM_00691 6.74e-281 - - - - - - - -
MIIHFEKM_00692 1.49e-286 - - - - - - - -
MIIHFEKM_00693 1.78e-105 - - - - - - - -
MIIHFEKM_00694 2.23e-105 - - - - - - - -
MIIHFEKM_00695 1.64e-242 - - - - - - - -
MIIHFEKM_00696 2.03e-92 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
MIIHFEKM_00697 0.0 aroB 2.7.1.71, 4.2.3.4 - H ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MIIHFEKM_00698 1.45e-280 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MIIHFEKM_00700 2.13e-264 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MIIHFEKM_00701 3.78e-112 ruvX - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MIIHFEKM_00702 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MIIHFEKM_00703 6.54e-46 - - - - - - - -
MIIHFEKM_00704 1.31e-84 - - - S - - - Bacterial protein of unknown function (DUF948)
MIIHFEKM_00705 7.34e-165 - 5.4.2.12 - G ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
MIIHFEKM_00706 2.01e-81 - - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
MIIHFEKM_00707 3.61e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MIIHFEKM_00708 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MIIHFEKM_00709 8.71e-119 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MIIHFEKM_00710 0.0 pbuX - - F ko:K03458 - ko00000 Permease family
MIIHFEKM_00711 1.5e-151 - - - M - - - Protein of unknown function (DUF3737)
MIIHFEKM_00712 6.73e-26 - 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I II
MIIHFEKM_00713 1.51e-226 - 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I II
MIIHFEKM_00714 5.4e-239 - - - K - - - TRANSCRIPTIONal
MIIHFEKM_00715 0.0 - 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
MIIHFEKM_00716 1.07e-181 - - - S ko:K07010 - ko00000,ko01002 Peptidase C26
MIIHFEKM_00717 1.63e-110 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
MIIHFEKM_00718 1.89e-133 - - - S - - - ABC-2 family transporter protein
MIIHFEKM_00719 2.02e-214 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MIIHFEKM_00720 1.42e-86 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MIIHFEKM_00721 5.23e-244 - - - K - - - Helix-turn-helix XRE-family like proteins
MIIHFEKM_00722 1.88e-214 add1 3.5.4.4 - F ko:K01488 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko01000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MIIHFEKM_00723 3.44e-182 - - - - - - - -
MIIHFEKM_00724 1.23e-67 - 4.2.99.21 - E ko:K04782 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Chorismate mutase type II
MIIHFEKM_00725 6.73e-207 - - - E - - - -acetyltransferase
MIIHFEKM_00726 1.82e-93 - - - K - - - Acetyltransferase (GNAT) family
MIIHFEKM_00727 3.03e-140 - - - F - - - adenylate kinase activity
MIIHFEKM_00728 8.85e-85 - - - S ko:K07133 - ko00000 AAA domain
MIIHFEKM_00729 0.0 tetM - - J ko:K18220 - br01600,ko00000,ko01504 elongation factor G
MIIHFEKM_00730 5.18e-228 - - - L ko:K07481 - ko00000 Transposase domain (DUF772)
MIIHFEKM_00731 4.41e-92 - - - K - - - sequence-specific DNA binding
MIIHFEKM_00732 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MIIHFEKM_00733 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
MIIHFEKM_00734 0.0 pta 2.3.1.8 - C ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphate acetyltransferase
MIIHFEKM_00735 4.94e-297 ackA 2.7.2.1 - H ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MIIHFEKM_00736 0.0 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MIIHFEKM_00738 1.05e-295 - - - - - - - -
MIIHFEKM_00739 0.0 glgX 3.2.1.68 CBM48,GH13 G ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
MIIHFEKM_00740 3.06e-158 - - - L - - - NUDIX domain
MIIHFEKM_00741 3.04e-235 - - - L - - - NIF3 (NGG1p interacting factor 3)
MIIHFEKM_00742 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MIIHFEKM_00744 7.75e-158 pdtaR - - T ko:K22010 - ko00000,ko00002,ko02022 Response regulator receiver domain protein
MIIHFEKM_00745 6.77e-153 aspA 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
MIIHFEKM_00747 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Pyruvate kinase
MIIHFEKM_00748 5.79e-230 terC - - P ko:K05794 - ko00000 Integral membrane protein, TerC family
MIIHFEKM_00749 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MIIHFEKM_00750 1.4e-152 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MIIHFEKM_00751 4.47e-315 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MIIHFEKM_00752 3.33e-211 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MIIHFEKM_00753 1.26e-236 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
MIIHFEKM_00754 4.24e-217 - - - P ko:K02074 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MIIHFEKM_00755 2.27e-185 znuB - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
MIIHFEKM_00756 7.88e-116 ispF 2.7.7.60, 4.6.1.12 - H ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MIIHFEKM_00757 1.02e-132 carD - - K ko:K07736 - ko00000,ko03000 CarD-like/TRCF domain
MIIHFEKM_00758 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MIIHFEKM_00759 3.21e-168 cseB - - T - - - Response regulator receiver domain protein
MIIHFEKM_00760 8.38e-258 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
MIIHFEKM_00761 3.71e-187 pyrE_1 - - S - - - Phosphoribosyl transferase domain
MIIHFEKM_00762 1.75e-197 - - - T - - - Eukaryotic phosphomannomutase
MIIHFEKM_00763 1.6e-72 - - - S - - - Zincin-like metallopeptidase
MIIHFEKM_00764 0.0 - - - - - - - -
MIIHFEKM_00765 0.0 - - - S - - - Glycosyl transferase, family 2
MIIHFEKM_00766 0.0 yvhJ - - K - - - Cell envelope-related transcriptional attenuator domain
MIIHFEKM_00767 8.99e-234 lytR2 - - K - - - Cell envelope-related transcriptional attenuator domain
MIIHFEKM_00768 1.17e-313 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
MIIHFEKM_00769 5.33e-61 whiB - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MIIHFEKM_00770 0.0 pdtaS 2.7.13.3 - T ko:K00936 - ko00000,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
MIIHFEKM_00771 6.93e-193 hlyIII - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
MIIHFEKM_00772 3.4e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MIIHFEKM_00773 2.24e-97 fkbP 5.2.1.8 - G ko:K01802 - ko00000,ko01000 Peptidyl-prolyl cis-trans
MIIHFEKM_00774 0.0 sdaA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase alpha chain
MIIHFEKM_00775 1.24e-136 - - - - - - - -
MIIHFEKM_00777 2.94e-238 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
MIIHFEKM_00778 2.96e-144 - - - S ko:K09009 - ko00000 Protein of unknown function (DUF501)
MIIHFEKM_00779 3.48e-128 - - - D - - - Septum formation initiator
MIIHFEKM_00780 8.66e-313 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MIIHFEKM_00781 3.38e-209 - - - U ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MIIHFEKM_00782 1.14e-224 - - - P ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 NMT1-like family
MIIHFEKM_00783 3.28e-165 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MIIHFEKM_00785 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MIIHFEKM_00786 3.18e-133 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MIIHFEKM_00787 7.24e-142 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
MIIHFEKM_00788 0.0 - - - S ko:K09118 - ko00000 Uncharacterised protein family (UPF0182)
MIIHFEKM_00789 9.99e-300 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
MIIHFEKM_00790 5.3e-22 - - - S - - - Selenoprotein, putative
MIIHFEKM_00791 0.0 cstA - - T ko:K06200 - ko00000 5TM C-terminal transporter carbon starvation CstA
MIIHFEKM_00792 2.88e-43 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
MIIHFEKM_00793 8.43e-94 - - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 (ABC) transporter
MIIHFEKM_00794 7.43e-130 - - - S - - - AAA domain, putative AbiEii toxin, Type IV TA system
MIIHFEKM_00796 1.2e-116 - - - K - - - Winged helix DNA-binding domain
MIIHFEKM_00797 3.72e-105 - - - F - - - Nucleoside 2-deoxyribosyltransferase
MIIHFEKM_00798 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
MIIHFEKM_00799 6.85e-54 - - - P ko:K04758 - ko00000,ko02000 FeoA
MIIHFEKM_00800 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
MIIHFEKM_00801 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MIIHFEKM_00802 5.42e-232 opcA - - G - - - Glucose-6-phosphate dehydrogenase subunit
MIIHFEKM_00803 9.91e-189 pgl 3.1.1.31 - G ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
MIIHFEKM_00804 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MIIHFEKM_00805 2.15e-22 M1-966 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
MIIHFEKM_00806 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MIIHFEKM_00807 2.17e-247 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MIIHFEKM_00808 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
MIIHFEKM_00809 1.53e-189 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MIIHFEKM_00810 0.0 - - - JKL - - - helicase superfamily c-terminal domain
MIIHFEKM_00811 2.85e-255 - - - S - - - Conserved hypothetical protein 698
MIIHFEKM_00812 0.0 rutG - - F ko:K02824,ko:K03458 - ko00000,ko02000 Permease family
MIIHFEKM_00813 1.66e-273 - - - I - - - Hydrolase, alpha beta domain protein
MIIHFEKM_00814 9.64e-47 - - - - - - - -
MIIHFEKM_00815 1.32e-76 - - - S - - - Cupin 2, conserved barrel domain protein
MIIHFEKM_00816 2.17e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MIIHFEKM_00817 4.3e-186 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MIIHFEKM_00818 0.0 pip 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 alpha/beta hydrolase fold
MIIHFEKM_00819 0.0 - - - T - - - Histidine kinase
MIIHFEKM_00820 3.72e-154 - - - K - - - helix_turn_helix, Lux Regulon
MIIHFEKM_00821 0.0 - - - MV ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
MIIHFEKM_00822 2.32e-219 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MIIHFEKM_00823 1.68e-136 ecfT - - P ko:K02008,ko:K16783,ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transmembrane transporter activity
MIIHFEKM_00824 0.0 ykoD - - P ko:K16784,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MIIHFEKM_00826 0.0 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Aminotransferase class-V
MIIHFEKM_00827 1.2e-211 pdxY 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
MIIHFEKM_00828 1.89e-114 yraN - - L ko:K07460 - ko00000 Belongs to the UPF0102 family
MIIHFEKM_00829 0.0 comM - - O ko:K07391 - ko00000 Magnesium chelatase, subunit ChlI C-terminal
MIIHFEKM_00830 1.44e-277 dprA - - LU ko:K04096 - ko00000 DNA recombination-mediator protein A
MIIHFEKM_00831 0.0 sdhA 1.3.5.1, 1.3.5.4, 1.4.3.16 - C ko:K00239,ko:K00278 ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 Succinate dehydrogenase flavoprotein subunit
MIIHFEKM_00832 1.36e-234 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
MIIHFEKM_00833 2.13e-157 safC - - S - - - O-methyltransferase
MIIHFEKM_00834 1.06e-192 fmt2 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
MIIHFEKM_00835 0.0 nhaA - - P ko:K03313 - ko00000,ko02000 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MIIHFEKM_00836 2.54e-311 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I II
MIIHFEKM_00839 0.0 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MIIHFEKM_00840 5.41e-160 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MIIHFEKM_00841 3.08e-147 clpP1 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MIIHFEKM_00842 0.0 - - - P ko:K03281 - ko00000 Voltage gated chloride channel
MIIHFEKM_00843 6.03e-306 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MIIHFEKM_00844 0.0 rnd 3.1.13.5 - J ko:K03684 - ko00000,ko01000,ko03016 3'-5' exonuclease
MIIHFEKM_00845 6.98e-224 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MIIHFEKM_00846 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
MIIHFEKM_00847 2.17e-43 - - - - - - - -
MIIHFEKM_00848 0.0 nadE 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MIIHFEKM_00849 1.09e-288 - - - S - - - Peptidase dimerisation domain
MIIHFEKM_00850 3.75e-155 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MIIHFEKM_00851 6.49e-304 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MIIHFEKM_00852 2.68e-232 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
MIIHFEKM_00853 4.86e-134 ppiA 5.2.1.8 - G ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MIIHFEKM_00854 0.0 relA 2.7.6.5, 3.1.7.2 - KT ko:K00951,ko:K01139 ko00230,map00230 ko00000,ko00001,ko01000,ko03009 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MIIHFEKM_00855 4.9e-108 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MIIHFEKM_00856 1.42e-62 - - - S - - - Domain of unknown function (DUF4193)
MIIHFEKM_00857 3.68e-312 - - - S - - - Protein of unknown function (DUF3071)
MIIHFEKM_00858 9.9e-274 - - - S - - - Type I phosphodiesterase / nucleotide pyrophosphatase
MIIHFEKM_00859 0.0 gyrA2 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
MIIHFEKM_00860 2.47e-222 - - - G ko:K05340 - ko00000,ko02000 Sugar transport protein
MIIHFEKM_00861 0.0 lhr - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
MIIHFEKM_00862 2.31e-56 - - - G - - - Major facilitator superfamily
MIIHFEKM_00864 5.36e-282 - - - G - - - Major Facilitator Superfamily
MIIHFEKM_00865 1.21e-288 - 2.4.1.345 GT4 M ko:K08256 - ko00000,ko01000,ko01003 Glycosyl transferase 4-like domain
MIIHFEKM_00866 0.0 gyrB2 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
MIIHFEKM_00867 2.66e-264 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MIIHFEKM_00868 8.16e-167 - - - - - - - -
MIIHFEKM_00869 7.37e-259 idsA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MIIHFEKM_00870 0.0 pknL 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 PASTA
MIIHFEKM_00871 1.73e-178 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
MIIHFEKM_00872 7.66e-127 - - - - - - - -
MIIHFEKM_00873 3.49e-247 trpD 2.4.2.18 - F ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MIIHFEKM_00874 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MIIHFEKM_00875 1.82e-160 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MIIHFEKM_00877 2.43e-147 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
MIIHFEKM_00878 6.98e-265 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MIIHFEKM_00879 1.78e-58 - - - S - - - Protein of unknown function (DUF3046)
MIIHFEKM_00880 6.75e-113 - - - K - - - Helix-turn-helix XRE-family like proteins
MIIHFEKM_00881 1.92e-144 cinA 3.5.1.42 - S ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
MIIHFEKM_00882 8.42e-156 pgsA 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIIHFEKM_00883 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 FtsK SpoIIIE family protein
MIIHFEKM_00884 4.34e-247 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MIIHFEKM_00885 0.0 miaB 2.8.4.3 - H ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MIIHFEKM_00886 3.69e-184 ywaC 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Region found in RelA / SpoT proteins
MIIHFEKM_00888 6.82e-254 - 1.4.1.12, 1.4.1.26 - S ko:K21672 ko00310,ko00330,ko00472,map00310,map00330,map00472 ko00000,ko00001,ko01000 Dihydrodipicolinate reductase, N-terminus
MIIHFEKM_00889 3.98e-295 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MIIHFEKM_00890 1.71e-301 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MIIHFEKM_00891 1.62e-236 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MIIHFEKM_00892 2.19e-271 - - - T - - - Histidine kinase
MIIHFEKM_00893 9.39e-149 - - - K - - - helix_turn_helix, Lux Regulon
MIIHFEKM_00894 5.27e-195 - - - S - - - Protein of unknown function DUF262
MIIHFEKM_00895 8.79e-10 - - - - - - - -
MIIHFEKM_00896 1.24e-55 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
MIIHFEKM_00897 0.0 nadE 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MIIHFEKM_00898 7.7e-129 nadE 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MIIHFEKM_00899 0.0 amyE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MIIHFEKM_00900 0.0 tnpA - - L - - - Transposase
MIIHFEKM_00901 0.0 - - - EGP - - - Major Facilitator Superfamily
MIIHFEKM_00902 1.51e-159 - - - G - - - Phosphoglycerate mutase family
MIIHFEKM_00903 2.38e-224 - - - - - - - -
MIIHFEKM_00904 1.74e-130 - - - S - - - GtrA-like protein
MIIHFEKM_00905 5.83e-255 - - - S - - - Protein conserved in bacteria
MIIHFEKM_00906 9.48e-83 - - - S - - - Macrophage migration inhibitory factor (MIF)
MIIHFEKM_00907 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Formate-tetrahydrofolate ligase
MIIHFEKM_00908 3.43e-281 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
MIIHFEKM_00909 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
MIIHFEKM_00910 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
MIIHFEKM_00911 6.8e-181 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
MIIHFEKM_00912 1.16e-285 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MIIHFEKM_00913 2.72e-142 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MIIHFEKM_00914 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MIIHFEKM_00915 4.9e-281 - - - I - - - PAP2 superfamily
MIIHFEKM_00917 2.86e-274 ino1 5.5.1.4 - I ko:K01858 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 ko00000,ko00001,ko01000 Myo-inositol-1-phosphate synthase
MIIHFEKM_00918 0.0 pbp5 - - M - - - Transglycosylase
MIIHFEKM_00919 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MIIHFEKM_00920 1.7e-155 - - - - - - - -
MIIHFEKM_00921 2.38e-252 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MIIHFEKM_00922 5.79e-126 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
MIIHFEKM_00923 2.52e-173 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
MIIHFEKM_00924 8.17e-141 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MIIHFEKM_00925 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III subunit gamma tau
MIIHFEKM_00926 6.12e-98 - - - S - - - TIGRFAM helicase secretion neighborhood TadE-like protein
MIIHFEKM_00927 5.66e-74 - - - U - - - TadE-like protein
MIIHFEKM_00928 4.93e-52 - - - S - - - Protein of unknown function (DUF4244)
MIIHFEKM_00929 3.93e-143 - - - U - - - Type II secretion system (T2SS), protein F
MIIHFEKM_00930 3.09e-151 - - - U ko:K12510 - ko00000,ko02044 Type ii secretion system
MIIHFEKM_00931 2.01e-291 cpaF - - U ko:K02283 - ko00000,ko02035,ko02044 Type II IV secretion system protein
MIIHFEKM_00932 3.59e-95 - - - D - - - bacterial-type flagellum organization
MIIHFEKM_00933 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MIIHFEKM_00934 5.22e-262 mutT 3.6.1.55 - LT ko:K03574 - ko00000,ko01000,ko03400 Phosphoglycerate mutase family
MIIHFEKM_00935 2.45e-168 - - - - - - - -
MIIHFEKM_00936 5.67e-151 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MIIHFEKM_00937 3.02e-254 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
MIIHFEKM_00938 0.0 - - - S ko:K03688 - ko00000 ABC1 family
MIIHFEKM_00939 3.85e-69 - - - S - - - granule-associated protein
MIIHFEKM_00940 6.15e-183 cobQ2 - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
MIIHFEKM_00941 0.0 murE - - M - - - Domain of unknown function (DUF1727)
MIIHFEKM_00942 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MIIHFEKM_00943 3.38e-51 - - - K - - - sequence-specific DNA binding
MIIHFEKM_00944 0.0 glnD 2.7.7.59 - O ko:K00990 ko02020,map02020 ko00000,ko00001,ko01000 Nucleotidyltransferase domain
MIIHFEKM_00945 6.28e-73 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Nitrogen regulatory protein P-II
MIIHFEKM_00946 1.79e-300 amt - - U ko:K03320 - ko00000,ko02000 Ammonium Transporter Family
MIIHFEKM_00947 1.95e-301 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MIIHFEKM_00948 7.53e-156 icaR - - K - - - Bacterial regulatory proteins, tetR family
MIIHFEKM_00949 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
MIIHFEKM_00951 6.61e-147 - - - - - - - -
MIIHFEKM_00952 9.61e-43 - - - K - - - transcriptional regulator
MIIHFEKM_00953 6.48e-213 - - - S - - - esterase of the alpha-beta hydrolase superfamily
MIIHFEKM_00954 2.93e-230 - - - P ko:K02077,ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MIIHFEKM_00955 0.0 - - - G ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MIIHFEKM_00956 7.69e-171 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MIIHFEKM_00957 2.58e-139 - - - S ko:K16926 - ko00000,ko00002,ko02000 Hypothetical bacterial integral membrane protein (Trep_Strep)
MIIHFEKM_00958 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
MIIHFEKM_00959 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
MIIHFEKM_00960 2.75e-136 - - - K - - - Psort location Cytoplasmic, score 8.87
MIIHFEKM_00961 1.16e-292 livK - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
MIIHFEKM_00962 1.34e-98 - - - - - - - -
MIIHFEKM_00963 6.76e-151 - 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MIIHFEKM_00964 5.42e-158 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MIIHFEKM_00965 0.0 - 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
MIIHFEKM_00966 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
MIIHFEKM_00967 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
MIIHFEKM_00968 7.97e-137 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MIIHFEKM_00969 8.06e-96 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MIIHFEKM_00970 0.0 - - - M - - - MacB-like periplasmic core domain
MIIHFEKM_00972 1.08e-43 - - - V ko:K02004 - ko00000,ko00002,ko02000 efflux transmembrane transporter activity
MIIHFEKM_00973 0.0 - - - E ko:K03293 - ko00000 Amino acid permease
MIIHFEKM_00974 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MIIHFEKM_00975 5.82e-165 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MIIHFEKM_00977 0.0 aroP - - E ko:K03293,ko:K11732 - ko00000,ko02000 aromatic amino acid transport protein AroP K03293
MIIHFEKM_00978 1.42e-187 - - - V ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MIIHFEKM_00979 8.53e-172 - - - V ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MIIHFEKM_00980 0.0 - - - G - - - N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
MIIHFEKM_00981 5.24e-34 - - - - - - - -
MIIHFEKM_00982 3.02e-171 - - - - - - - -
MIIHFEKM_00983 2.49e-148 - - - S - - - Protein of unknown function, DUF624
MIIHFEKM_00984 5.1e-240 - - - K - - - helix_turn _helix lactose operon repressor
MIIHFEKM_00985 2.28e-175 - 3.2.1.25 - G ko:K01192 ko00511,ko04142,map00511,map04142 ko00000,ko00001,ko01000 beta-mannosidase
MIIHFEKM_00986 0.0 bglA 3.2.1.21 - G ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
MIIHFEKM_00987 3.67e-281 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MIIHFEKM_00988 0.0 - 3.1.1.53 - E ko:K05970 - ko00000,ko01000 Carbohydrate esterase, sialic acid-specific acetylesterase
MIIHFEKM_00989 1.53e-258 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MIIHFEKM_00990 0.0 - - - EGP - - - Sugar (and other) transporter
MIIHFEKM_00992 2.26e-64 - - - S - - - Protein of unknown function (DUF1778)
MIIHFEKM_00993 5.95e-121 - - - S - - - Acetyltransferase (GNAT) family
MIIHFEKM_00994 0.0 scrT - - G - - - Transporter major facilitator family protein
MIIHFEKM_00995 3.05e-234 - - - S - - - Domain of unknown function (DUF4392)
MIIHFEKM_00996 6.55e-309 accBC3 6.3.4.14, 6.4.1.2, 6.4.1.3 - I ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase C-terminal domain
MIIHFEKM_00997 9.6e-144 livK - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
MIIHFEKM_00998 0.0 - - - G - - - Transporter major facilitator family protein
MIIHFEKM_00999 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Domain of unknown function (DUF1964)
MIIHFEKM_01000 1e-244 - - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MIIHFEKM_01001 1.73e-287 livK - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
MIIHFEKM_01002 6.62e-194 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
MIIHFEKM_01003 1.67e-202 - - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
MIIHFEKM_01004 6.84e-210 livM - - U ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MIIHFEKM_01005 2.82e-306 - - - U ko:K01997,ko:K11956 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MIIHFEKM_01006 7.85e-84 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIIHFEKM_01007 3.73e-224 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIIHFEKM_01008 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MIIHFEKM_01009 8.45e-249 fbaA 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
MIIHFEKM_01010 0.0 - 3.2.1.8, 3.5.1.104 - G ko:K01181,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
MIIHFEKM_01011 2.86e-213 - - - K - - - LysR substrate binding domain
MIIHFEKM_01012 7.83e-262 adh 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
MIIHFEKM_01013 3.29e-189 - - - GM - - - NmrA-like family
MIIHFEKM_01014 1.97e-111 - - - C - - - Flavodoxin
MIIHFEKM_01015 1.47e-51 - - - K - - - helix_turn_helix, mercury resistance
MIIHFEKM_01016 1.47e-120 - - - C - - - Flavodoxin
MIIHFEKM_01017 0.0 - - - P - - - nitric oxide dioxygenase activity
MIIHFEKM_01018 2.27e-05 - - - I - - - acetylesterase activity
MIIHFEKM_01019 1.43e-250 - 1.1.1.91 - C ko:K05882 - ko00000,ko01000 Aldo/keto reductase family
MIIHFEKM_01020 5.51e-206 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
MIIHFEKM_01021 2.08e-244 - - - S ko:K06889 - ko00000 Dienelactone hydrolase family
MIIHFEKM_01022 1.13e-111 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Cupin domain
MIIHFEKM_01023 1.87e-181 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MIIHFEKM_01024 0.0 - - - S - - - cellulose binding
MIIHFEKM_01025 2.39e-113 ogt 2.1.1.63 - L ko:K00567,ko:K07443 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MIIHFEKM_01026 8.74e-69 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
MIIHFEKM_01027 2.14e-14 - - - S - - - NADPH-dependent FMN reductase
MIIHFEKM_01028 4.63e-293 - - - EGP ko:K08156,ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
MIIHFEKM_01029 8.61e-158 - - - E - - - SOS response associated peptidase (SRAP)
MIIHFEKM_01030 6.74e-271 - - - V - - - Beta-lactamase
MIIHFEKM_01031 1.98e-232 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MIIHFEKM_01033 0.0 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MIIHFEKM_01034 0.0 - - - S ko:K07126 - ko00000 Sel1-like repeats.
MIIHFEKM_01035 6.47e-149 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MIIHFEKM_01036 0.0 degP - - O ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Domain present in PSD-95, Dlg, and ZO-1/2.
MIIHFEKM_01037 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
MIIHFEKM_01038 0.0 fprA 1.18.1.2, 1.19.1.1 - C ko:K00528 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase
MIIHFEKM_01040 4.74e-48 - - - S - - - Transglycosylase associated protein
MIIHFEKM_01041 4.12e-47 - - - S - - - Transglycosylase associated protein
MIIHFEKM_01042 1.39e-229 rrmA 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
MIIHFEKM_01043 3.36e-77 - - - - - - - -
MIIHFEKM_01044 1.54e-271 pldB 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Serine aminopeptidase, S33
MIIHFEKM_01045 5.05e-161 - - - EG - - - EamA-like transporter family
MIIHFEKM_01046 0.0 pepX 3.4.14.5 - E ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Dipeptidyl peptidase IV (DPP IV) N-terminal region
MIIHFEKM_01047 1.83e-167 fhaA - - T - - - Protein of unknown function (DUF2662)
MIIHFEKM_01048 2.44e-94 fhaB - - T - - - Inner membrane component of T3SS, cytoplasmic domain
MIIHFEKM_01049 0.0 pstP 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
MIIHFEKM_01050 0.0 rodA - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MIIHFEKM_01051 0.0 pbpA - - M ko:K05364 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
MIIHFEKM_01052 1.37e-248 pknA 2.7.11.1 - T ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
MIIHFEKM_01053 0.0 pknB 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
MIIHFEKM_01054 7.93e-156 trpG 2.6.1.85, 4.1.3.27 - EH ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 para-aminobenzoate synthase glutamine amidotransferase component II
MIIHFEKM_01055 1.07e-285 srtB 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
MIIHFEKM_01056 1.4e-177 - - - S - - - Bacterial protein of unknown function (DUF881)
MIIHFEKM_01057 2.13e-46 crgA - - D - - - Involved in cell division
MIIHFEKM_01058 0.0 - - - L - - - ribosomal rna small subunit methyltransferase
MIIHFEKM_01059 1.76e-164 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
MIIHFEKM_01060 9.18e-49 - - - - - - - -
MIIHFEKM_01061 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MIIHFEKM_01062 3.73e-104 - - - I - - - Sterol carrier protein
MIIHFEKM_01063 1.4e-66 - - - S - - - Protein of unknown function (DUF3073)
MIIHFEKM_01064 2.9e-264 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MIIHFEKM_01065 6.14e-110 - - - - - - - -
MIIHFEKM_01066 0.0 wcoI - - DM - - - Psort location CytoplasmicMembrane, score
MIIHFEKM_01067 0.0 - - - S - - - Protein of unknown function (DUF4012)
MIIHFEKM_01068 1.13e-132 etp 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Low molecular weight phosphatase family
MIIHFEKM_01069 0.0 maf - - DF ko:K06287 - ko00000 Maf-like protein
MIIHFEKM_01070 0.0 fadD 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 long-chain-fatty acid CoA ligase
MIIHFEKM_01071 0.0 - - - V ko:K06147,ko:K06148,ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter transmembrane region
MIIHFEKM_01072 8.76e-261 - - - S - - - EpsG family
MIIHFEKM_01073 5.53e-205 - - GT2 S ko:K12990 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyl transferase family 2
MIIHFEKM_01074 6.67e-237 - - - S - - - Glycosyl transferase family 2
MIIHFEKM_01075 1.84e-119 - - - M - - - Glycosyltransferase family 28 C-terminal domain
MIIHFEKM_01076 6.41e-111 - - - M - - - Oligosaccharide biosynthesis protein Alg14 like
MIIHFEKM_01077 2.14e-282 - - - M - - - epimerase dehydratase
MIIHFEKM_01078 2.15e-153 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MIIHFEKM_01079 2.31e-199 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MIIHFEKM_01080 1.3e-174 - - - L - - - Protein of unknown function (DUF1524)
MIIHFEKM_01081 6.59e-310 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MIIHFEKM_01082 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
MIIHFEKM_01083 2.01e-65 - - - - - - - -
MIIHFEKM_01084 0.0 - - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
MIIHFEKM_01085 4.92e-208 - - - S - - - Glycosyl transferase family 2
MIIHFEKM_01086 1.53e-252 - - - M - - - transferase activity, transferring glycosyl groups
MIIHFEKM_01087 0.0 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
MIIHFEKM_01088 5.09e-302 ugd 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 UDP binding domain
MIIHFEKM_01089 3.61e-234 - - - M - - - Capsular polysaccharide synthesis protein
MIIHFEKM_01090 1.34e-210 - - GT2 S ko:K12992 ko02025,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyltransferase like family 2
MIIHFEKM_01091 9.26e-187 - - - M - - - Domain of unknown function (DUF4422)
MIIHFEKM_01092 6.81e-220 - - GT2 S ko:K12990 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyl transferase family 2
MIIHFEKM_01093 0.0 - - - - - - - -
MIIHFEKM_01094 4.03e-245 - 2.7.8.12 GT2 S ko:K09809,ko:K19427 - ko00000,ko01000 Glycosyltransferase like family 2
MIIHFEKM_01095 6.8e-219 - - - S - - - Glycosyl transferase family 2
MIIHFEKM_01096 0.0 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
MIIHFEKM_01097 4.52e-237 - - - M - - - Glycosyl transferase family 2
MIIHFEKM_01098 1.28e-263 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MIIHFEKM_01099 0.0 rfbD 1.1.1.133, 5.1.3.13 - M ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MIIHFEKM_01100 8.58e-218 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MIIHFEKM_01101 0.0 - - - S - - - Protein of unknown function (DUF4012)
MIIHFEKM_01102 3.45e-239 - - - M - - - Glycosyl transferase family 2
MIIHFEKM_01103 0.0 - - - S - - - Predicted membrane protein (DUF2142)
MIIHFEKM_01104 1.57e-100 - - - - - - - -
MIIHFEKM_01105 0.0 - - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
MIIHFEKM_01106 3.66e-241 - - - S ko:K21688 - ko00000 G5
MIIHFEKM_01107 1.18e-86 trxA 1.8.1.9 - O ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Belongs to the thioredoxin family
MIIHFEKM_01108 1.17e-109 - - - F - - - Domain of unknown function (DUF4916)
MIIHFEKM_01109 3.34e-220 - - - I - - - Alpha/beta hydrolase family
MIIHFEKM_01110 2.11e-273 nudC 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
MIIHFEKM_01111 5.74e-94 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
MIIHFEKM_01112 0.0 - - - S - - - Uncharacterized conserved protein (DUF2183)
MIIHFEKM_01113 0.0 ptrB 3.4.21.83 - E ko:K01354 ko05142,ko05143,map05142,map05143 ko00000,ko00001,ko01000,ko01002 Peptidase, S9A B C family, catalytic domain protein
MIIHFEKM_01114 1.06e-220 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MIIHFEKM_01115 1.84e-28 - - - - - - - -
MIIHFEKM_01116 5.69e-105 - - - J - - - TM2 domain
MIIHFEKM_01117 5.28e-283 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Biotin/lipoate A/B protein ligase family
MIIHFEKM_01118 1.64e-178 crp - - K ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
MIIHFEKM_01119 0.0 pon1 - - M - - - Transglycosylase
MIIHFEKM_01120 2.6e-282 namA - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
MIIHFEKM_01121 2.16e-282 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
MIIHFEKM_01122 9.89e-143 ppm1 2.4.1.83 GT2 S ko:K00721 ko00510,ko01100,map00510,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase family 2
MIIHFEKM_01123 5.19e-184 - - - K - - - DeoR C terminal sensor domain
MIIHFEKM_01124 0.0 galT 2.7.7.12 - C ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 Galactose-1-phosphate uridyl transferase, N-terminal domain
MIIHFEKM_01125 3.52e-295 galK 2.7.1.6, 2.7.7.12 - G ko:K00849,ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GHMP kinase family. GalK subfamily
MIIHFEKM_01127 1.45e-192 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
MIIHFEKM_01128 1.69e-57 - - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
MIIHFEKM_01129 0.0 - - - S ko:K09157 - ko00000 UPF0210 protein
MIIHFEKM_01130 3.3e-165 spoU 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MIIHFEKM_01131 5.51e-239 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 FES
MIIHFEKM_01132 2.17e-68 - - - - - - - -
MIIHFEKM_01133 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIIHFEKM_01134 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIIHFEKM_01135 1.49e-138 - - - T - - - Forkhead associated domain
MIIHFEKM_01136 5.62e-135 - - - B - - - Belongs to the OprB family
MIIHFEKM_01137 0.0 - - - E - - - Transglutaminase-like superfamily
MIIHFEKM_01138 3.4e-266 - - - S - - - Protein of unknown function DUF58
MIIHFEKM_01139 9.88e-163 - - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
MIIHFEKM_01140 0.0 - - - S - - - Fibronectin type 3 domain
MIIHFEKM_01141 0.0 pknK 2.7.11.1 - KLT ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
MIIHFEKM_01142 0.0 - - - L - - - PD-(D/E)XK nuclease superfamily
MIIHFEKM_01143 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Belongs to the helicase family. UvrD subfamily
MIIHFEKM_01144 2.04e-171 - - - K - - - -acetyltransferase
MIIHFEKM_01145 0.0 - - - G - - - Major Facilitator Superfamily
MIIHFEKM_01146 7.91e-173 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MIIHFEKM_01147 3.72e-212 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MIIHFEKM_01148 0.0 rnj - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MIIHFEKM_01149 0.0 pepN 3.4.11.2 - E ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Peptidase family M1 domain
MIIHFEKM_01150 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MIIHFEKM_01151 1.64e-162 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MIIHFEKM_01152 0.0 - - - L - - - Psort location Cytoplasmic, score
MIIHFEKM_01153 0.0 - - - S - - - zinc finger
MIIHFEKM_01154 1.34e-130 vsr - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MIIHFEKM_01155 2.09e-217 aspB 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K10907,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-V
MIIHFEKM_01156 5.11e-165 tmp1 - - S - - - Domain of unknown function (DUF4391)
MIIHFEKM_01158 7.29e-244 - - - S ko:K18353 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01504 Endonuclease/Exonuclease/phosphatase family
MIIHFEKM_01159 4.21e-60 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MIIHFEKM_01160 1.04e-305 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MIIHFEKM_01161 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Anaerobic ribonucleoside-triphosphate reductase
MIIHFEKM_01162 2.07e-190 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MIIHFEKM_01163 3.76e-183 - - - - - - - -
MIIHFEKM_01164 5.83e-78 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
MIIHFEKM_01165 8.85e-131 - - - S - - - Protein of unknown function (DUF1211)
MIIHFEKM_01166 0.0 hgdC - - I - - - CoA enzyme activase uncharacterised domain (DUF2229)
MIIHFEKM_01167 0.0 egtA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Glutamate-cysteine ligase family 2(GCS2)
MIIHFEKM_01168 0.0 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MIIHFEKM_01169 7.49e-24 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR associated protein Cas2
MIIHFEKM_01170 5.26e-284 - - - S ko:K19131 - ko00000,ko02048 CRISPR-associated protein GSU0053 (Cas_GSU0053)
MIIHFEKM_01171 0.0 - - - - ko:K19132 - ko00000,ko02048 -
MIIHFEKM_01172 0.0 cas3 - - L ko:K07012 - ko00000,ko01000,ko02048 CRISPR-associated helicase Cas3
MIIHFEKM_01173 4.02e-265 - - - - ko:K19133 - ko00000,ko02048 -
MIIHFEKM_01174 6.34e-66 - - - - - - - -
MIIHFEKM_01177 1.31e-129 vsr - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MIIHFEKM_01178 2.28e-132 - - - S - - - NADPH-dependent FMN reductase
MIIHFEKM_01179 6.41e-127 - - - K - - - MarR family
MIIHFEKM_01180 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
MIIHFEKM_01181 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
MIIHFEKM_01182 2.3e-22 - - - - - - - -
MIIHFEKM_01183 5.39e-62 - - - - - - - -
MIIHFEKM_01184 1.7e-188 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MIIHFEKM_01185 3.48e-33 - - - - - - - -
MIIHFEKM_01186 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MIIHFEKM_01187 1.12e-08 - - - L - - - This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MIIHFEKM_01188 8.06e-315 - - - S - - - COG1512 Beta-propeller domains of methanol dehydrogenase type
MIIHFEKM_01189 3.33e-149 pspA - - KT ko:K03969 - ko00000 PspA/IM30 family
MIIHFEKM_01190 0.0 - - - EGP ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
MIIHFEKM_01191 0.0 dppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
MIIHFEKM_01192 3.18e-41 - - - - - - - -
MIIHFEKM_01193 1.13e-150 - - - - - - - -
MIIHFEKM_01194 0.0 lysI - - E ko:K03758 - ko00000,ko02000 Amino acid permease
MIIHFEKM_01195 0.0 tetM - - J ko:K18220 - br01600,ko00000,ko01504 Elongation factor G, domain IV
MIIHFEKM_01198 1.92e-115 - - - S - - - Domain of unknown function (DUF4234)
MIIHFEKM_01199 1.13e-26 - 2.7.1.95 - F ko:K00897 - ko00000,ko01000,ko01504 Phosphotransferase enzyme family
MIIHFEKM_01200 4.75e-110 - 2.7.1.95 - F ko:K00897 - ko00000,ko01000,ko01504 Phosphotransferase enzyme family
MIIHFEKM_01201 0.0 bglB 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
MIIHFEKM_01202 6.38e-154 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Aldo/keto reductase family
MIIHFEKM_01203 1.14e-30 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MIIHFEKM_01204 1.46e-210 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
MIIHFEKM_01205 1.01e-86 - - - T ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
MIIHFEKM_01206 5.7e-30 - - - K - - - SpoVT / AbrB like domain
MIIHFEKM_01207 1.06e-52 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
MIIHFEKM_01208 0.0 - - - - - - - -
MIIHFEKM_01209 0.0 - - - - - - - -
MIIHFEKM_01210 1.94e-143 - - - - - - - -
MIIHFEKM_01211 0.0 - - - - - - - -
MIIHFEKM_01212 2.61e-60 - - - S - - - Type II restriction endonuclease EcoO109I
MIIHFEKM_01213 2.53e-243 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
MIIHFEKM_01215 1.15e-31 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MIIHFEKM_01216 2.13e-75 - - - S - - - MazG-like family
MIIHFEKM_01219 3.27e-25 - - - - - - - -
MIIHFEKM_01220 3.41e-155 - - - - - - - -
MIIHFEKM_01221 5.12e-139 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
MIIHFEKM_01222 1.79e-214 - - - - - - - -
MIIHFEKM_01223 2.44e-191 - - - Q - - - ubiE/COQ5 methyltransferase family
MIIHFEKM_01224 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MIIHFEKM_01225 6.65e-198 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
MIIHFEKM_01226 2.87e-101 - - - - - - - -
MIIHFEKM_01227 4.87e-187 - - - S ko:K07043 - ko00000 Protein of unknown function DUF45
MIIHFEKM_01230 3.45e-68 gcs2 - - S ko:K06048 - ko00000,ko01000 A circularly permuted ATPgrasp
MIIHFEKM_01231 1.39e-95 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MIIHFEKM_01232 6.85e-218 - 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Glycosyl hydrolase family 26
MIIHFEKM_01233 4.42e-307 - - - EGP - - - Transporter major facilitator family protein
MIIHFEKM_01234 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MIIHFEKM_01235 3.88e-207 - - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
MIIHFEKM_01236 3.27e-279 - - - V - - - VanZ like family
MIIHFEKM_01237 2.65e-108 - - - S - - - Transmembrane domain of unknown function (DUF3566)
MIIHFEKM_01238 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MIIHFEKM_01239 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MIIHFEKM_01240 2.35e-117 - - - S - - - Protein of unknown function (DUF721)
MIIHFEKM_01241 0.0 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MIIHFEKM_01242 7.9e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MIIHFEKM_01243 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MIIHFEKM_01244 9.33e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
MIIHFEKM_01245 8.06e-234 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Membrane protein insertase, YidC Oxa1 family
MIIHFEKM_01246 4.13e-122 jag - - S ko:K06346 - ko00000 Putative single-stranded nucleic acids-binding domain
MIIHFEKM_01247 1.82e-174 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
MIIHFEKM_01248 2.2e-225 parA - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
MIIHFEKM_01249 0.0 parB - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MIIHFEKM_01250 2.29e-228 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MIIHFEKM_01251 0.0 mviN - - KLT ko:K03980 - ko00000,ko01011,ko02000 MviN-like protein
MIIHFEKM_01252 0.0 - - - - - - - -
MIIHFEKM_01253 1.51e-239 mutT4 - - L - - - Belongs to the Nudix hydrolase family
MIIHFEKM_01254 0.0 pcnA 2.7.7.19, 2.7.7.72 - J ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 Probable RNA and SrmB- binding site of polymerase A
MIIHFEKM_01255 1.51e-145 - - - S - - - LytR cell envelope-related transcriptional attenuator
MIIHFEKM_01256 1.44e-227 ispE 2.7.1.148 - F ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MIIHFEKM_01257 1.13e-208 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MIIHFEKM_01258 7.02e-285 rpfB - - S ko:K21688 - ko00000 G5
MIIHFEKM_01260 3.47e-114 - - - O - - - Thioredoxin
MIIHFEKM_01261 0.0 - - - KLT - - - Protein tyrosine kinase
MIIHFEKM_01262 1.41e-241 - - - U ko:K10716 - ko00000,ko02000 Ion channel
MIIHFEKM_01263 6.27e-270 ugpC - - E ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MIIHFEKM_01264 0.0 - - - KLT - - - Domain of unknown function (DUF4032)
MIIHFEKM_01265 3.62e-223 rlmB 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIIHFEKM_01266 0.0 pacL2 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
MIIHFEKM_01267 5.78e-143 dcd 3.5.4.13 - F ko:K01494 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dCTP deaminase family
MIIHFEKM_01268 2.47e-253 - - - D - - - nuclear chromosome segregation
MIIHFEKM_01269 3.82e-232 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
MIIHFEKM_01270 0.0 nhaP - - P ko:K03316 - ko00000 Sodium/hydrogen exchanger family
MIIHFEKM_01271 4.78e-110 tadA 3.5.4.1, 3.5.4.33 - FJ ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MIIHFEKM_01272 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Glycosyl hydrolase family 36 N-terminal domain
MIIHFEKM_01273 2.57e-297 - - - GK - - - ROK family
MIIHFEKM_01274 1.66e-308 - - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MIIHFEKM_01275 1.35e-238 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MIIHFEKM_01276 3.43e-206 - - - G ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MIIHFEKM_01277 0.0 - - - G - - - Raffinose synthase or seed imbibition protein Sip1
MIIHFEKM_01278 2.78e-237 - - - K - - - Psort location Cytoplasmic, score
MIIHFEKM_01280 0.0 - 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MIIHFEKM_01281 1.43e-284 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
MIIHFEKM_01282 2.72e-187 cobB2 - - K ko:K12410 - ko00000,ko01000 Sir2 family
MIIHFEKM_01283 2.59e-257 - - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein domain
MIIHFEKM_01284 0.0 - 3.2.1.185 GH127 S ko:K09955,ko:K18205 - ko00000,ko01000 Beta-L-arabinofuranosidase, GH127
MIIHFEKM_01285 0.0 - - - G ko:K03292 - ko00000 Psort location CytoplasmicMembrane, score 10.00
MIIHFEKM_01286 4.17e-236 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MIIHFEKM_01287 1.26e-311 hom 1.1.1.3, 2.7.2.4 - E ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
MIIHFEKM_01288 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MIIHFEKM_01289 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MIIHFEKM_01290 0.0 - 3.2.1.45 GH30 G ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 TIM-barrel domain
MIIHFEKM_01291 1.23e-86 psp1 3.5.99.10 - J ko:K09022 - ko00000,ko01000 Endoribonuclease L-PSP
MIIHFEKM_01292 9.46e-144 - - - P ko:K02026,ko:K10242 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MIIHFEKM_01293 2.42e-235 - 2.4.1.20 GT36 G ko:K00702 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase 36 superfamily, catalytic domain
MIIHFEKM_01295 1.96e-219 ybbN - - O ko:K05838 - ko00000,ko03110 Tetratricopeptide repeat
MIIHFEKM_01296 6.91e-235 - - - - - - - -
MIIHFEKM_01297 9.9e-276 - - - - - - - -
MIIHFEKM_01298 2.58e-223 - 5.2.1.8 - M ko:K01802 - ko00000,ko01000 FKBP-type peptidyl-prolyl cis-trans isomerase
MIIHFEKM_01299 4.85e-180 nucS - - L ko:K07503 - ko00000,ko01000 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MIIHFEKM_01300 1.28e-65 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MIIHFEKM_01301 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MIIHFEKM_01302 1.72e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MIIHFEKM_01303 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MIIHFEKM_01304 7.19e-196 atpH - - C ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MIIHFEKM_01305 2.71e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MIIHFEKM_01306 2.54e-42 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MIIHFEKM_01307 3.54e-188 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MIIHFEKM_01308 1.61e-261 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MIIHFEKM_01309 0.0 - - - EGP - - - Major Facilitator Superfamily
MIIHFEKM_01310 6.66e-235 rihB 3.2.2.1, 3.2.2.8 - F ko:K01239,ko:K01250,ko:K10213 ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
MIIHFEKM_01312 2.08e-270 - - - - - - - -
MIIHFEKM_01313 5.62e-37 - - - - - - - -
MIIHFEKM_01314 2.44e-86 - - - - - - - -
MIIHFEKM_01315 9.79e-182 - - - D ko:K03466 - ko00000,ko03036 ftsk spoiiie
MIIHFEKM_01316 8.16e-159 - - - S - - - Plasmid replication protein
MIIHFEKM_01317 9.18e-49 - - - - - - - -
MIIHFEKM_01318 1.39e-284 - - - L - - - HNH endonuclease
MIIHFEKM_01319 1.17e-280 - - - H - - - Adenine-specific methyltransferase EcoRI
MIIHFEKM_01320 2.89e-292 - - - L - - - Phage integrase family
MIIHFEKM_01321 0.0 frc 2.8.3.15, 2.8.3.16 - C ko:K07544,ko:K07749 ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MIIHFEKM_01322 4.97e-276 - 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 hydrolase family 5
MIIHFEKM_01323 5.91e-222 - - - S ko:K07088 - ko00000 Membrane transport protein
MIIHFEKM_01324 0.0 oxc 4.1.1.8 - EH ko:K01577 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Thiamine pyrophosphate enzyme, central domain
MIIHFEKM_01325 0.0 - - - P - - - Voltage gated chloride channel
MIIHFEKM_01326 0.0 - - - M ko:K13735 ko05100,map05100 ko00000,ko00001 domain protein
MIIHFEKM_01327 0.0 - - - K - - - RNA polymerase II activating transcription factor binding
MIIHFEKM_01328 0.0 glgE 2.4.99.16 GH13 G ko:K16147 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
MIIHFEKM_01329 3.01e-120 ppa 3.6.1.1 - C ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MIIHFEKM_01330 3.16e-197 - - - - - - - -
MIIHFEKM_01331 1.67e-191 glnR - - KT - - - Transcriptional regulatory protein, C terminal
MIIHFEKM_01332 4.39e-178 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MIIHFEKM_01333 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MIIHFEKM_01334 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MIIHFEKM_01335 1e-135 lrp_3 - - K ko:K03719 - ko00000,ko03000,ko03036 helix_turn_helix ASNC type
MIIHFEKM_01336 1.91e-83 tyrA 5.4.99.5 - E ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase type II
MIIHFEKM_01337 0.0 - - - S - - - domain protein
MIIHFEKM_01338 0.0 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MIIHFEKM_01339 0.0 - - - H - - - Flavin containing amine oxidoreductase
MIIHFEKM_01340 1.87e-68 - - - S - - - Protein of unknown function (DUF2469)
MIIHFEKM_01341 7.27e-252 - - - J - - - Acetyltransferase (GNAT) domain
MIIHFEKM_01342 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MIIHFEKM_01343 0.0 gatA 6.3.5.6, 6.3.5.7 - F ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MIIHFEKM_01344 4.42e-34 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MIIHFEKM_01345 8.48e-198 - - - S - - - ABC-type transport system involved in multi-copper enzyme maturation permease component
MIIHFEKM_01346 2.77e-176 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MIIHFEKM_01347 7.8e-196 trmH 2.1.1.34 - J ko:K00556 - ko00000,ko01000,ko03016 RNA methyltransferase TrmH family
MIIHFEKM_01348 6.33e-148 pyrE1 - - F - - - Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MIIHFEKM_01349 0.0 - - - P - - - E1-E2 ATPase
MIIHFEKM_01350 0.0 clpB - - O ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MIIHFEKM_01351 1.32e-201 - - - Q - - - Fumarylacetoacetate (FAA) hydrolase family
MIIHFEKM_01352 4.56e-109 - - - - - - - -
MIIHFEKM_01353 0.0 - - - M - - - domain protein
MIIHFEKM_01354 0.0 - - - Q - - - von Willebrand factor (vWF) type A domain
MIIHFEKM_01355 5.75e-244 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
MIIHFEKM_01356 3.91e-200 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MIIHFEKM_01357 3.88e-251 gluQ 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MIIHFEKM_01358 7.84e-218 - - - M - - - Protein of unknown function (DUF3152)
MIIHFEKM_01359 7.69e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MIIHFEKM_01363 6.82e-174 - - - T - - - Pfam Adenylate and Guanylate cyclase catalytic domain
MIIHFEKM_01364 3.61e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MIIHFEKM_01365 1.06e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MIIHFEKM_01366 1.77e-124 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
MIIHFEKM_01367 5.36e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MIIHFEKM_01368 3.31e-243 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MIIHFEKM_01369 9.03e-223 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIIHFEKM_01370 0.0 - - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 Major Facilitator Superfamily
MIIHFEKM_01371 3.76e-218 iunH2 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
MIIHFEKM_01372 4.45e-253 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MIIHFEKM_01373 0.0 hrpA 3.6.4.13 - L ko:K03578 - ko00000,ko01000 Helicase associated domain (HA2) Add an annotation
MIIHFEKM_01374 1.27e-150 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase (PrmA)
MIIHFEKM_01375 0.0 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MIIHFEKM_01376 3.25e-225 ldh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MIIHFEKM_01377 2.23e-212 czcD - - P ko:K16264 - ko00000,ko02000 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MIIHFEKM_01378 1.06e-165 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MIIHFEKM_01379 3.77e-14 - - - M - - - LysM domain
MIIHFEKM_01380 1.85e-125 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MIIHFEKM_01381 3.75e-288 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MIIHFEKM_01382 0.0 - - - L - - - DNA helicase
MIIHFEKM_01383 5.36e-111 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MIIHFEKM_01384 2.11e-249 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MIIHFEKM_01385 3.19e-119 - - - D - - - Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MIIHFEKM_01386 0.0 ftsI 3.4.16.4 - M ko:K03587 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 Penicillin-binding protein, transpeptidase domain protein
MIIHFEKM_01387 9.34e-204 - - - M - - - Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MIIHFEKM_01388 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MIIHFEKM_01389 1.21e-267 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MIIHFEKM_01390 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MIIHFEKM_01391 0.0 ftsW 2.4.1.227 GT28 D ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 Belongs to the SEDS family
MIIHFEKM_01392 2.95e-206 murG 2.4.1.227, 6.3.2.8 GT28 M ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MIIHFEKM_01393 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MIIHFEKM_01394 2.95e-301 ftsQ - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein FtsQ
MIIHFEKM_01395 3.14e-200 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MIIHFEKM_01396 5.75e-76 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MIIHFEKM_01397 1.98e-243 dppB - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MIIHFEKM_01398 3.5e-272 dppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MIIHFEKM_01399 0.0 - - - P ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MIIHFEKM_01402 0.0 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
MIIHFEKM_01407 4.49e-291 - - - T - - - AAA domain
MIIHFEKM_01408 3.06e-39 - - - - - - - -
MIIHFEKM_01412 0.00013 - - - L - - - Helix-turn-helix domain
MIIHFEKM_01414 3.23e-271 int8 - - L - - - Phage integrase family
MIIHFEKM_01415 6.33e-109 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MIIHFEKM_01416 2.02e-217 - 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
MIIHFEKM_01417 1.51e-284 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
MIIHFEKM_01418 6.13e-127 - - - F - - - NUDIX domain
MIIHFEKM_01419 0.0 pepP 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Aminopeptidase P, N-terminal domain
MIIHFEKM_01420 3.55e-192 - - - - - - - -
MIIHFEKM_01421 2.34e-248 - - - T - - - Histidine kinase
MIIHFEKM_01422 5.94e-149 - - - KT - - - cheY-homologous receiver domain
MIIHFEKM_01423 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Mur ligase middle domain
MIIHFEKM_01424 2e-255 - - - V - - - Acetyltransferase (GNAT) domain
MIIHFEKM_01425 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MIIHFEKM_01426 2.85e-169 sigH - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MIIHFEKM_01427 1.32e-72 - - - - - - - -
MIIHFEKM_01428 3.12e-253 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MIIHFEKM_01429 4.77e-229 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MIIHFEKM_01430 3.2e-116 ybaK - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MIIHFEKM_01431 1.3e-264 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MIIHFEKM_01432 1.68e-193 - 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Thiamin pyrophosphokinase, vitamin B1 binding domain
MIIHFEKM_01433 2.25e-136 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MIIHFEKM_01434 1.79e-34 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L35
MIIHFEKM_01435 1.63e-82 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MIIHFEKM_01436 9.9e-214 xerD - - D ko:K03733,ko:K04763 - ko00000,ko03036 recombinase XerD
MIIHFEKM_01437 1.55e-194 soj - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
MIIHFEKM_01438 1.01e-200 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX hydrolase
MIIHFEKM_01439 0.0 nanT - - U ko:K03290,ko:K08178,ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
MIIHFEKM_01440 0.0 typA - - T ko:K06207 - ko00000 Elongation factor G C-terminus
MIIHFEKM_01441 2.34e-118 - - - - - - - -
MIIHFEKM_01442 6.3e-277 pheA 4.2.1.51, 5.4.99.5 - E ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
MIIHFEKM_01443 7.85e-270 tyrA 1.3.1.12 - E ko:K00210,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydrogenase
MIIHFEKM_01444 3.14e-54 - - - - - - - -
MIIHFEKM_01445 0.0 - - - MV ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
MIIHFEKM_01446 4.76e-190 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MIIHFEKM_01447 1.44e-228 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
MIIHFEKM_01448 0.0 dppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
MIIHFEKM_01449 1.48e-199 dppB - - EP ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MIIHFEKM_01450 9.25e-220 dppC - - EP ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
MIIHFEKM_01451 0.0 dppD - - P ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MIIHFEKM_01452 2.11e-153 - - - - - - - -
MIIHFEKM_01453 4.59e-217 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease/Exonuclease/phosphatase family
MIIHFEKM_01454 5.41e-204 - - - S - - - Protein of unknown function (DUF3710)
MIIHFEKM_01455 2.68e-176 - - - S - - - Protein of unknown function (DUF3159)
MIIHFEKM_01456 0.0 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MIIHFEKM_01457 3.81e-133 - - - - - - - -
MIIHFEKM_01458 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
MIIHFEKM_01459 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MIIHFEKM_01460 3.99e-47 - - - - - - - -
MIIHFEKM_01461 3.31e-158 - 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Bacterial transferase hexapeptide repeat protein
MIIHFEKM_01462 0.0 - - - S - - - Protein of unknown function DUF262
MIIHFEKM_01463 1.05e-299 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
MIIHFEKM_01464 2.34e-266 amsE - - M - - - Glycosyl transferase family 2
MIIHFEKM_01466 3.65e-253 - - - S - - - Glycosyltransferase, group 2 family protein
MIIHFEKM_01467 0.0 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
MIIHFEKM_01468 0.0 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
MIIHFEKM_01469 0.0 glfT 2.4.1.288 GT2 S ko:K16650 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
MIIHFEKM_01470 2.57e-226 - - - M - - - Glycosyl hydrolases family 25
MIIHFEKM_01471 0.0 - - - M - - - Glycosyl hydrolases family 25
MIIHFEKM_01472 2.61e-239 tnp3503b - - L - - - Transposase and inactivated derivatives
MIIHFEKM_01473 1.62e-78 - - - S - - - Leucine-rich repeat (LRR) protein
MIIHFEKM_01474 3.31e-130 - - - M - - - hydrolase, family 25
MIIHFEKM_01475 1.2e-172 - - - - - - - -
MIIHFEKM_01476 0.0 - - - S - - - Polysaccharide pyruvyl transferase
MIIHFEKM_01477 0.0 - - - GM ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MIIHFEKM_01478 5.64e-194 tagG - - U ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
MIIHFEKM_01479 0.0 - - - S - - - Glycosyltransferase like family 2
MIIHFEKM_01481 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MIIHFEKM_01482 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MIIHFEKM_01483 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
MIIHFEKM_01484 0.0 - - - V - - - ABC transporter permease
MIIHFEKM_01485 4.6e-249 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MIIHFEKM_01486 8.09e-195 - - - T ko:K06950 - ko00000 HD domain
MIIHFEKM_01487 1.17e-217 - - - S - - - Glutamine amidotransferase domain
MIIHFEKM_01488 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MIIHFEKM_01489 1.7e-235 tatD - - L ko:K03424 - ko00000,ko01000 TatD related DNase
MIIHFEKM_01490 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
MIIHFEKM_01491 6.89e-166 - - - - - - - -
MIIHFEKM_01492 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
MIIHFEKM_01493 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
MIIHFEKM_01494 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MIIHFEKM_01495 2.01e-167 - - - - - - - -
MIIHFEKM_01496 9.93e-94 - - - - - - - -
MIIHFEKM_01497 3.49e-221 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MIIHFEKM_01498 0.0 pmt 2.4.1.109 GT39 O ko:K00728 ko00514,ko00515,ko01100,map00514,map00515,map01100 ko00000,ko00001,ko01000,ko01003 C-terminal four TMM region of protein-O-mannosyltransferase
MIIHFEKM_01499 1.2e-201 - - - I - - - alpha/beta hydrolase fold
MIIHFEKM_01500 2.12e-174 dedA1 - - S ko:K03975 - ko00000 SNARE associated Golgi protein
MIIHFEKM_01502 6.19e-163 - - - S - - - GyrI-like small molecule binding domain
MIIHFEKM_01503 0.0 bgl2 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Fibronectin type III-like domain
MIIHFEKM_01504 4.71e-146 - - - K - - - Bacterial regulatory proteins, tetR family
MIIHFEKM_01505 1.2e-166 - - - S - - - HAD hydrolase, family IA, variant 3
MIIHFEKM_01506 1.43e-119 hspR - - K ko:K13640 - ko00000,ko03000 transcriptional regulator, MerR family
MIIHFEKM_01507 4.87e-238 dnaJ - - O ko:K03686,ko:K05516 - ko00000,ko03029,ko03036,ko03110 DnaJ molecular chaperone homology domain
MIIHFEKM_01508 6.25e-132 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MIIHFEKM_01509 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MIIHFEKM_01511 4.59e-247 - - - K - - - Psort location Cytoplasmic, score
MIIHFEKM_01512 8.73e-187 traX - - S - - - TraX protein
MIIHFEKM_01513 1.55e-190 - - - S ko:K07025 - ko00000 HAD-hyrolase-like
MIIHFEKM_01514 0.0 apuB 3.2.1.41, 3.2.1.68 CBM48,GH13 G ko:K01200,ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
MIIHFEKM_01515 2.29e-226 malG - - G ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MIIHFEKM_01516 0.0 malC - - G ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MIIHFEKM_01517 5.8e-303 malE - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MIIHFEKM_01518 0.0 malL 2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16 GH13,GH31 G ko:K01187,ko:K05341,ko:K05343 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
MIIHFEKM_01519 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
MIIHFEKM_01520 3.35e-140 - - - S - - - Protein of unknown function, DUF624
MIIHFEKM_01521 1.7e-197 - - - G ko:K02026,ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MIIHFEKM_01522 1.1e-199 msmF - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MIIHFEKM_01523 4.41e-232 - - - K - - - Psort location Cytoplasmic, score
MIIHFEKM_01525 8.24e-308 amyE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MIIHFEKM_01526 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
MIIHFEKM_01527 1.4e-148 gpm2 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
MIIHFEKM_01528 4.02e-89 - - - S - - - Protein of unknown function (DUF4235)
MIIHFEKM_01529 1.44e-181 nfrA - - C - - - Nitroreductase family
MIIHFEKM_01530 4.78e-59 - - - - - - - -
MIIHFEKM_01531 3.96e-124 iolT - - EGP - - - Major facilitator Superfamily
MIIHFEKM_01532 5.15e-134 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Exonuclease, DNA polymerase III, epsilon subunit family
MIIHFEKM_01533 1.07e-165 - - - K - - - acetyltransferase
MIIHFEKM_01534 2.07e-251 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MIIHFEKM_01535 8.77e-208 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
MIIHFEKM_01536 3e-280 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MIIHFEKM_01537 3.64e-142 - - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score 9.99
MIIHFEKM_01538 2.49e-295 - 2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83 - E ko:K00812,ko:K08969,ko:K10206,ko:K10907,ko:K14260,ko:K14261 ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
MIIHFEKM_01539 1.29e-145 glnP2 - - E ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MIIHFEKM_01540 3.77e-157 glnP - - E ko:K02029,ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MIIHFEKM_01541 2.41e-204 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ATP binding protein of ABC transporter for glutamate aspartate K02028
MIIHFEKM_01542 9.92e-211 glnH - - ET ko:K02030,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MIIHFEKM_01543 7.34e-197 hflK - - O - - - prohibitin homologues
MIIHFEKM_01544 1.21e-207 - - - S - - - Patatin-like phospholipase
MIIHFEKM_01545 3.84e-186 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MIIHFEKM_01546 7.78e-223 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
MIIHFEKM_01547 3.37e-156 - - - S - - - Vitamin K epoxide reductase
MIIHFEKM_01548 1.14e-213 PPA1328 3.1.3.97, 3.1.4.57 - S ko:K07053,ko:K20859 ko00440,map00440 ko00000,ko00001,ko01000 DNA polymerase alpha chain like domain
MIIHFEKM_01549 1.45e-27 - - - S - - - Protein of unknown function (DUF3107)
MIIHFEKM_01550 0.0 mphA - - S - - - Aminoglycoside phosphotransferase
MIIHFEKM_01551 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MIIHFEKM_01552 0.0 - - - S - - - Zincin-like metallopeptidase
MIIHFEKM_01553 9.43e-233 sdrC - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MIIHFEKM_01554 2.42e-96 - - - S - - - Protein of unknown function (DUF3052)
MIIHFEKM_01555 1.94e-105 - - - - - - - -
MIIHFEKM_01557 0.0 - - - NU - - - Tfp pilus assembly protein FimV
MIIHFEKM_01558 5.92e-280 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MIIHFEKM_01559 1.48e-291 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MIIHFEKM_01560 0.0 - - - I - - - acetylesterase activity
MIIHFEKM_01561 3.68e-170 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MIIHFEKM_01562 5.72e-195 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 - H ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MIIHFEKM_01564 4.16e-299 - - - F - - - nucleoside hydrolase
MIIHFEKM_01565 3.8e-264 - - - P - - - NMT1/THI5 like
MIIHFEKM_01566 7.44e-190 - - - P - - - Binding-protein-dependent transport system inner membrane component
MIIHFEKM_01567 0.0 fosC 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
MIIHFEKM_01568 9.04e-316 lacY - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
MIIHFEKM_01569 3.28e-257 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MIIHFEKM_01570 7.04e-79 - - - S - - - Thiamine-binding protein
MIIHFEKM_01571 0.0 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 - H ko:K03147,ko:K14153 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MIIHFEKM_01572 7.5e-125 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MIIHFEKM_01573 0.0 glyQS 6.1.1.14 - J ko:K01880 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of glycine to tRNA(Gly)
MIIHFEKM_01574 3.31e-316 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIIHFEKM_01575 7.23e-283 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MIIHFEKM_01576 2.22e-103 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MIIHFEKM_01577 1.18e-56 - - - S ko:K02221 - ko00000,ko02044 YGGT family
MIIHFEKM_01578 7.28e-149 - - - V - - - DivIVA protein
MIIHFEKM_01579 1.34e-127 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MIIHFEKM_01580 5.2e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MIIHFEKM_01582 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III alpha subunit
MIIHFEKM_01583 0.0 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MIIHFEKM_01584 2.17e-287 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MIIHFEKM_01585 2.09e-143 hisB 3.1.3.15, 4.2.1.19 - E ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Imidazoleglycerol-phosphate dehydratase
MIIHFEKM_01586 4.58e-167 - - - - - - - -
MIIHFEKM_01587 2.09e-155 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MIIHFEKM_01588 3.66e-167 hisA 5.3.1.16, 5.3.1.24 - E ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Histidine biosynthesis protein
MIIHFEKM_01589 1.28e-230 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2252)
MIIHFEKM_01590 0.0 glnA2 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MIIHFEKM_01591 0.0 - - - S - - - Threonine/Serine exporter, ThrE
MIIHFEKM_01592 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MIIHFEKM_01593 4.08e-216 - - - S - - - Oxidoreductase, aldo keto reductase family protein
MIIHFEKM_01594 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
MIIHFEKM_01595 1.14e-166 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Class II Aldolase and Adducin N-terminal domain
MIIHFEKM_01596 0.0 araB - - G - - - FGGY family of carbohydrate kinases, C-terminal domain
MIIHFEKM_01597 0.0 - 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 arabinose metabolic process
MIIHFEKM_01598 2.57e-250 - - - K - - - helix_turn _helix lactose operon repressor
MIIHFEKM_01599 1.59e-71 - - - - - - - -
MIIHFEKM_01600 3.58e-213 - 3.6.3.17 - G ko:K02056,ko:K10545 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MIIHFEKM_01601 1.3e-48 - - - - - - - -
MIIHFEKM_01602 7.3e-275 - - - K - - - helix_turn _helix lactose operon repressor
MIIHFEKM_01603 3.01e-165 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
MIIHFEKM_01604 4.68e-314 - - - P ko:K03699 - ko00000,ko02042 Transporter associated domain
MIIHFEKM_01605 1.87e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MIIHFEKM_01606 9.15e-158 - - - K - - - Bacterial regulatory proteins, tetR family
MIIHFEKM_01607 7.41e-289 - - - G - - - MFS/sugar transport protein
MIIHFEKM_01608 0.0 - 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Beta-galactosidase trimerisation domain
MIIHFEKM_01609 0.0 - 3.2.1.45 GH30 G ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 TIM-barrel domain

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)