Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MAKJDLNK_00004	3.91e-31	-	-	-	-	-	-	-	-
MAKJDLNK_00005	1.06e-312	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MAKJDLNK_00006	5.96e-110	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
MAKJDLNK_00007	0.0	-	-	-	EGP	-	-	-	Major Facilitator
MAKJDLNK_00008	4.67e-127	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
MAKJDLNK_00009	1.84e-63	-	-	-	-	-	-	-	-
MAKJDLNK_00010	3.78e-271	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MAKJDLNK_00011	1.87e-180	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MAKJDLNK_00012	7.27e-285	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MAKJDLNK_00013	1.19e-162	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MAKJDLNK_00014	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MAKJDLNK_00015	9.88e-57	-	-	-	-	-	-	-	-
MAKJDLNK_00016	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MAKJDLNK_00017	4.9e-83	-	-	-	S	-	-	-	Domain of unknown function DUF302
MAKJDLNK_00018	1.9e-198	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MAKJDLNK_00019	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
MAKJDLNK_00020	1.65e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
MAKJDLNK_00021	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
MAKJDLNK_00022	1.33e-239	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MAKJDLNK_00023	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
MAKJDLNK_00024	1.41e-142	-	-	-	-	-	-	-	-
MAKJDLNK_00025	6.39e-235	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
MAKJDLNK_00026	4.99e-153	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MAKJDLNK_00027	9.96e-82	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MAKJDLNK_00028	7.52e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MAKJDLNK_00029	1.13e-133	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
MAKJDLNK_00030	8.26e-309	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MAKJDLNK_00031	7.57e-135	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
MAKJDLNK_00032	4.24e-257	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
MAKJDLNK_00034	4.86e-53	-	-	-	-	-	-	-	-
MAKJDLNK_00036	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MAKJDLNK_00037	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MAKJDLNK_00038	3.95e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MAKJDLNK_00039	5.23e-230	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
MAKJDLNK_00040	6.67e-192	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MAKJDLNK_00042	4.29e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
MAKJDLNK_00043	3.68e-171	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKJDLNK_00044	5.42e-275	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MAKJDLNK_00045	9.51e-161	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MAKJDLNK_00046	6.83e-76	-	-	-	S	-	-	-	Small secreted protein
MAKJDLNK_00047	1.53e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
MAKJDLNK_00048	9.14e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MAKJDLNK_00049	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MAKJDLNK_00050	1.24e-146	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MAKJDLNK_00051	4.66e-178	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
MAKJDLNK_00052	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MAKJDLNK_00053	7.57e-208	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MAKJDLNK_00054	4.15e-137	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MAKJDLNK_00055	3.44e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MAKJDLNK_00056	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
MAKJDLNK_00057	1.08e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MAKJDLNK_00058	6.95e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MAKJDLNK_00059	5.22e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MAKJDLNK_00060	4.67e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MAKJDLNK_00061	2.58e-24	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
MAKJDLNK_00062	7.57e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
MAKJDLNK_00063	6.88e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
MAKJDLNK_00064	2.29e-275	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
MAKJDLNK_00065	1.61e-64	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
MAKJDLNK_00066	1.62e-120	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MAKJDLNK_00067	5.53e-145	yqeK	-	-	H	-	-	-	Hydrolase, HD family
MAKJDLNK_00068	2.79e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MAKJDLNK_00069	3.16e-181	yqeM	-	-	Q	-	-	-	Methyltransferase
MAKJDLNK_00070	1.37e-272	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MAKJDLNK_00071	2.79e-126	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
MAKJDLNK_00072	7.89e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MAKJDLNK_00073	1.38e-155	csrR	-	-	K	-	-	-	response regulator
MAKJDLNK_00074	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MAKJDLNK_00075	7.67e-298	-	-	-	V	-	-	-	MatE
MAKJDLNK_00076	4.54e-91	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
MAKJDLNK_00077	5.83e-199	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MAKJDLNK_00078	8.13e-62	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MAKJDLNK_00079	1.06e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MAKJDLNK_00080	4.08e-117	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MAKJDLNK_00081	1.44e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MAKJDLNK_00082	1.49e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MAKJDLNK_00083	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MAKJDLNK_00084	5.91e-151	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
MAKJDLNK_00085	1.81e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MAKJDLNK_00086	0.0	-	-	-	S	-	-	-	membrane
MAKJDLNK_00087	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MAKJDLNK_00088	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MAKJDLNK_00089	3.66e-127	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MAKJDLNK_00090	1.68e-148	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
MAKJDLNK_00091	1.14e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
MAKJDLNK_00092	1.83e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
MAKJDLNK_00093	5.91e-93	yqhL	-	-	P	-	-	-	Rhodanese-like protein
MAKJDLNK_00094	1.43e-32	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
MAKJDLNK_00095	4.25e-219	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MAKJDLNK_00096	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MAKJDLNK_00097	4.76e-19	-	-	-	-	-	-	-	-
MAKJDLNK_00098	1.9e-201	-	-	-	-	-	-	-	-
MAKJDLNK_00099	2.34e-226	-	-	-	-	-	-	-	-
MAKJDLNK_00100	1.1e-120	-	-	-	S	-	-	-	Protein conserved in bacteria
MAKJDLNK_00102	3.17e-149	-	-	-	K	-	-	-	Transcriptional regulator
MAKJDLNK_00103	1.89e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MAKJDLNK_00104	1.2e-70	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
MAKJDLNK_00105	8.74e-62	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MAKJDLNK_00106	4.18e-263	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MAKJDLNK_00107	2.1e-94	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
MAKJDLNK_00108	3.29e-90	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MAKJDLNK_00109	1.16e-205	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MAKJDLNK_00110	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MAKJDLNK_00111	1.64e-25	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MAKJDLNK_00112	2.93e-202	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MAKJDLNK_00113	1.14e-189	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
MAKJDLNK_00114	4.92e-99	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MAKJDLNK_00115	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MAKJDLNK_00116	5.98e-12	-	-	-	S	-	-	-	YjcQ protein
MAKJDLNK_00118	1.87e-269	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAKJDLNK_00121	1.27e-18	yrvD	-	-	S	-	-	-	Pfam:DUF1049
MAKJDLNK_00122	3.64e-58	-	-	-	NU	-	-	-	Domain of unknown function (DUF5067)
MAKJDLNK_00125	3.63e-91	-	-	-	-	-	-	-	-
MAKJDLNK_00126	4.31e-32	-	-	-	K	-	-	-	Helix-turn-helix domain
MAKJDLNK_00127	3.54e-05	-	-	-	K	ko:K15546,ko:K15773	-	ko00000,ko02048,ko03000	sequence-specific DNA binding
MAKJDLNK_00128	7.17e-141	-	-	-	K	-	-	-	Phage regulatory protein
MAKJDLNK_00133	1.9e-223	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
MAKJDLNK_00134	1.72e-210	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
MAKJDLNK_00135	3.44e-122	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MAKJDLNK_00136	1.13e-31	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MAKJDLNK_00141	3.96e-53	-	-	-	-	-	-	-	-
MAKJDLNK_00142	4.84e-100	-	-	-	L	-	-	-	Phage terminase, small subunit
MAKJDLNK_00143	0.0	-	-	-	S	-	-	-	Phage Terminase
MAKJDLNK_00145	3.15e-235	-	-	-	S	-	-	-	Phage portal protein
MAKJDLNK_00146	6.73e-226	-	-	-	G	ko:K06904	-	ko00000	Phage capsid family
MAKJDLNK_00147	1.77e-62	-	-	-	-	-	-	-	-
MAKJDLNK_00151	2.16e-123	-	-	-	S	-	-	-	Phage tail tube protein
MAKJDLNK_00152	2.4e-62	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
MAKJDLNK_00153	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MAKJDLNK_00154	6.48e-209	-	-	-	S	-	-	-	Phage tail protein
MAKJDLNK_00155	0.0	-	-	-	M	-	-	-	Prophage endopeptidase tail
MAKJDLNK_00156	1.12e-112	spoIVFA	-	GT2,GT4	D	ko:K05802,ko:K06401,ko:K20444,ko:K22051	-	ko00000,ko01000,ko01005,ko02000	peptidase
MAKJDLNK_00163	1.53e-39	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
MAKJDLNK_00164	1.14e-268	-	-	-	M	-	-	-	hydrolase, family 25
MAKJDLNK_00165	1.03e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MAKJDLNK_00166	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MAKJDLNK_00167	8.29e-273	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MAKJDLNK_00168	8.28e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MAKJDLNK_00169	3.95e-278	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
MAKJDLNK_00170	1.57e-260	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MAKJDLNK_00171	3.81e-260	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MAKJDLNK_00174	2.85e-239	-	-	-	L	-	-	-	PFAM Integrase catalytic region
MAKJDLNK_00175	4.67e-228	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
MAKJDLNK_00177	6.81e-112	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
MAKJDLNK_00178	1.74e-24	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MAKJDLNK_00179	5.38e-158	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
MAKJDLNK_00180	1.59e-37	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
MAKJDLNK_00181	3.85e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MAKJDLNK_00182	4.36e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MAKJDLNK_00183	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MAKJDLNK_00184	2.16e-97	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MAKJDLNK_00185	7.43e-97	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
MAKJDLNK_00186	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
MAKJDLNK_00187	1.01e-184	yidA	-	-	S	-	-	-	hydrolase
MAKJDLNK_00188	1.89e-78	-	-	-	-	-	-	-	-
MAKJDLNK_00189	7.69e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MAKJDLNK_00190	9.91e-302	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MAKJDLNK_00191	2.13e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MAKJDLNK_00192	3.99e-166	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
MAKJDLNK_00193	5.68e-123	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MAKJDLNK_00194	4.04e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MAKJDLNK_00195	4.04e-205	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MAKJDLNK_00196	3.57e-205	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MAKJDLNK_00197	7.92e-129	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MAKJDLNK_00198	3.29e-189	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
MAKJDLNK_00199	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MAKJDLNK_00200	9.96e-209	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
MAKJDLNK_00201	1.95e-271	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
MAKJDLNK_00202	2.31e-165	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
MAKJDLNK_00203	6.18e-238	-	-	-	-	-	-	-	-
MAKJDLNK_00204	9.58e-287	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
MAKJDLNK_00205	7.95e-222	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
MAKJDLNK_00206	0.0	-	-	-	L	-	-	-	DNA helicase
MAKJDLNK_00207	1.28e-258	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MAKJDLNK_00208	9.46e-199	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MAKJDLNK_00210	3.03e-181	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
MAKJDLNK_00212	1.93e-213	-	-	-	K	-	-	-	Transcriptional regulator
MAKJDLNK_00213	9.21e-83	-	-	-	C	-	-	-	Aldo keto reductase
MAKJDLNK_00214	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
MAKJDLNK_00215	1.81e-251	adh1	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MAKJDLNK_00216	1.06e-70	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
MAKJDLNK_00217	1.98e-176	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MAKJDLNK_00218	3.88e-160	-	-	-	C	-	-	-	nitroreductase
MAKJDLNK_00219	1.5e-226	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
MAKJDLNK_00220	5.26e-23	fdrA	-	-	C	ko:K02381	-	ko00000	CoA-ligase
MAKJDLNK_00221	4e-259	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
MAKJDLNK_00222	4.31e-122	allC	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	Peptidase family M20/M25/M40
MAKJDLNK_00223	1.13e-167	-	3.5.2.3, 3.5.2.5	-	F	ko:K01465,ko:K01466	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MAKJDLNK_00224	2.43e-77	-	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
MAKJDLNK_00225	6.46e-105	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
MAKJDLNK_00226	3.61e-44	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
MAKJDLNK_00228	1.43e-21	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MAKJDLNK_00229	1.61e-57	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
MAKJDLNK_00230	1.24e-59	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MAKJDLNK_00233	9.6e-45	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
MAKJDLNK_00234	2.23e-101	yphH	-	-	S	-	-	-	Cupin domain
MAKJDLNK_00235	2.09e-78	-	-	-	L	-	-	-	Helix-turn-helix domain
MAKJDLNK_00236	2.7e-316	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MAKJDLNK_00237	2.41e-232	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MAKJDLNK_00238	9.23e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MAKJDLNK_00239	1.49e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MAKJDLNK_00240	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MAKJDLNK_00241	9.14e-66	ylxQ	-	-	J	-	-	-	ribosomal protein
MAKJDLNK_00242	3.71e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
MAKJDLNK_00243	6.7e-283	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MAKJDLNK_00244	8.99e-109	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MAKJDLNK_00245	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MAKJDLNK_00246	6.19e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MAKJDLNK_00247	1.49e-252	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MAKJDLNK_00248	2.87e-263	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MAKJDLNK_00249	5.88e-176	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
MAKJDLNK_00250	2.68e-274	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
MAKJDLNK_00251	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MAKJDLNK_00252	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MAKJDLNK_00253	8.02e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MAKJDLNK_00254	1.17e-173	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MAKJDLNK_00255	2.7e-185	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MAKJDLNK_00256	6.51e-122	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MAKJDLNK_00257	1.38e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MAKJDLNK_00258	4.14e-198	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MAKJDLNK_00259	3.14e-181	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MAKJDLNK_00260	1.09e-61	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
MAKJDLNK_00261	6.86e-176	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
MAKJDLNK_00262	5.08e-149	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
MAKJDLNK_00263	1.05e-36	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
MAKJDLNK_00264	1.97e-49	ynzC	-	-	S	-	-	-	UPF0291 protein
MAKJDLNK_00265	1.25e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MAKJDLNK_00266	2.21e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
MAKJDLNK_00267	2.76e-155	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
MAKJDLNK_00268	8.75e-307	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
MAKJDLNK_00269	1.95e-110	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
MAKJDLNK_00270	1.25e-46	-	-	-	M	-	-	-	the current gene model (or a revised gene model) may contain a
MAKJDLNK_00272	7.93e-45	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MAKJDLNK_00273	3.47e-46	-	-	-	M	-	-	-	domain protein
MAKJDLNK_00274	1.99e-11	-	-	-	Q	-	-	-	Signal peptide protein, YSIRK family
MAKJDLNK_00275	5.8e-33	yitW	-	-	S	-	-	-	DNA methyltransferase
MAKJDLNK_00276	3.09e-141	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MAKJDLNK_00277	1.89e-81	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
MAKJDLNK_00280	1.59e-76	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MAKJDLNK_00281	2.6e-73	-	-	-	L	-	-	-	Helix-turn-helix domain
MAKJDLNK_00283	4.94e-47	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
MAKJDLNK_00284	1.35e-166	topA2	5.99.1.2	-	G	ko:K03169	-	ko00000,ko01000,ko03032	Topoisomerase IA
MAKJDLNK_00287	8.97e-177	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
MAKJDLNK_00291	7.7e-268	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
MAKJDLNK_00292	6.75e-75	-	-	-	-	-	-	-	-
MAKJDLNK_00296	2.47e-57	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
MAKJDLNK_00299	3.55e-28	-	-	-	-	-	-	-	-
MAKJDLNK_00300	6.36e-230	-	-	-	U	-	-	-	type IV secretory pathway VirB4
MAKJDLNK_00302	2.33e-33	-	-	-	M	-	-	-	CHAP domain
MAKJDLNK_00306	3.34e-07	ydiL	-	-	S	ko:K07052	-	ko00000	protease
MAKJDLNK_00307	1.68e-19	-	-	-	-	ko:K18640	-	ko00000,ko04812	-
MAKJDLNK_00310	4.22e-164	-	-	-	L	-	-	-	PFAM Integrase catalytic region
MAKJDLNK_00311	2.63e-44	-	-	-	-	-	-	-	-
MAKJDLNK_00312	1.6e-250	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MAKJDLNK_00313	4.17e-84	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain protein
MAKJDLNK_00314	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
MAKJDLNK_00315	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
MAKJDLNK_00316	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
MAKJDLNK_00317	7.93e-47	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
MAKJDLNK_00318	6.98e-57	-	-	-	S	-	-	-	ASCH
MAKJDLNK_00319	4.39e-133	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
MAKJDLNK_00320	4.95e-201	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MAKJDLNK_00321	2.43e-98	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
MAKJDLNK_00322	6.73e-111	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
MAKJDLNK_00323	3.39e-10	-	-	-	C	-	-	-	Domain of unknown function (DUF4145)
MAKJDLNK_00324	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
MAKJDLNK_00325	9.21e-19	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
MAKJDLNK_00326	4.3e-30	-	-	-	D	ko:K19158	-	ko00000,ko01000,ko02048	mRNA cleavage
MAKJDLNK_00327	2.59e-235	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
MAKJDLNK_00329	4.35e-247	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
MAKJDLNK_00331	2.29e-96	-	3.5.3.18	-	E	ko:K01482	-	ko00000,ko01000,ko04147	Amidinotransferase
MAKJDLNK_00332	5.51e-116	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
MAKJDLNK_00333	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
MAKJDLNK_00334	1.28e-67	-	-	-	K	-	-	-	2 iron, 2 sulfur cluster binding
MAKJDLNK_00335	1.25e-26	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
MAKJDLNK_00336	1.81e-80	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
MAKJDLNK_00337	1.22e-154	-	-	-	Q	-	-	-	Methyltransferase domain
MAKJDLNK_00339	1.35e-133	-	-	-	S	-	-	-	CAAX protease self-immunity
MAKJDLNK_00340	1.52e-129	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MAKJDLNK_00341	1.71e-59	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MAKJDLNK_00342	9.79e-62	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MAKJDLNK_00343	2.39e-131	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MAKJDLNK_00344	4.82e-277	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MAKJDLNK_00345	7.36e-135	-	-	-	-	-	-	-	-
MAKJDLNK_00346	1.76e-113	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MAKJDLNK_00347	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
MAKJDLNK_00348	2.89e-44	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
MAKJDLNK_00349	7.4e-180	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
MAKJDLNK_00350	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
MAKJDLNK_00351	5.26e-205	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
MAKJDLNK_00352	3.12e-135	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
MAKJDLNK_00353	5.17e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
MAKJDLNK_00354	4.06e-243	mocA	-	-	S	-	-	-	Oxidoreductase
MAKJDLNK_00355	1.42e-305	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
MAKJDLNK_00357	1.38e-98	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
MAKJDLNK_00358	1.59e-99	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MAKJDLNK_00359	1.94e-213	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
MAKJDLNK_00360	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
MAKJDLNK_00361	5.86e-192	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MAKJDLNK_00362	4.37e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
MAKJDLNK_00364	8.33e-188	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
MAKJDLNK_00365	1.73e-152	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
MAKJDLNK_00366	1.71e-191	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
MAKJDLNK_00367	3.84e-116	cps3F	-	-	-	-	-	-	-
MAKJDLNK_00368	1.34e-39	-	-	-	M	-	-	-	biosynthesis protein
MAKJDLNK_00369	1.21e-62	cps3I	-	-	G	-	-	-	Acyltransferase family
MAKJDLNK_00370	9.38e-279	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
MAKJDLNK_00371	1.88e-254	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
MAKJDLNK_00374	2.76e-19	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
MAKJDLNK_00376	3.82e-23	-	-	-	-	-	-	-	-
MAKJDLNK_00377	1.31e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MAKJDLNK_00378	3.47e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MAKJDLNK_00379	2.92e-184	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MAKJDLNK_00380	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MAKJDLNK_00381	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MAKJDLNK_00382	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MAKJDLNK_00383	6.82e-46	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MAKJDLNK_00384	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MAKJDLNK_00385	4.66e-110	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MAKJDLNK_00386	3.91e-138	-	-	-	-	-	-	-	-
MAKJDLNK_00387	1.52e-173	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MAKJDLNK_00388	9.74e-229	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
MAKJDLNK_00389	4.21e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
MAKJDLNK_00390	6.43e-117	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MAKJDLNK_00391	4e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MAKJDLNK_00392	2.34e-212	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
MAKJDLNK_00393	1.61e-192	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MAKJDLNK_00394	2.4e-151	ybbR	-	-	S	-	-	-	YbbR-like protein
MAKJDLNK_00395	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MAKJDLNK_00396	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MAKJDLNK_00397	4.4e-69	-	-	-	-	-	-	-	-
MAKJDLNK_00398	1.17e-262	oatA	-	-	I	-	-	-	Acyltransferase
MAKJDLNK_00399	8.67e-193	XK27_02985	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MAKJDLNK_00400	4.69e-106	lytE	-	-	M	-	-	-	Lysin motif
MAKJDLNK_00401	6.96e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MAKJDLNK_00402	6.02e-216	-	-	-	K	-	-	-	LysR substrate binding domain
MAKJDLNK_00403	3.15e-163	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MAKJDLNK_00404	7.71e-192	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
MAKJDLNK_00405	8.77e-117	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
MAKJDLNK_00406	1.5e-231	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
MAKJDLNK_00407	1.82e-230	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
MAKJDLNK_00408	6.53e-162	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
MAKJDLNK_00409	1.37e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
MAKJDLNK_00410	1.8e-76	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
MAKJDLNK_00412	5.65e-170	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
MAKJDLNK_00413	0.0	yclK	-	-	T	-	-	-	Histidine kinase
MAKJDLNK_00414	1.24e-196	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MAKJDLNK_00415	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
MAKJDLNK_00417	5.85e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MAKJDLNK_00418	6.63e-232	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
MAKJDLNK_00420	5.94e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MAKJDLNK_00421	7.67e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
MAKJDLNK_00422	9.42e-234	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
MAKJDLNK_00423	3.81e-275	-	-	-	M	-	-	-	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
MAKJDLNK_00424	8.07e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
MAKJDLNK_00425	2.8e-87	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MAKJDLNK_00426	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MAKJDLNK_00427	1.78e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MAKJDLNK_00428	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MAKJDLNK_00429	1.23e-119	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MAKJDLNK_00430	3.92e-80	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MAKJDLNK_00431	2.13e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MAKJDLNK_00432	5.66e-168	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MAKJDLNK_00433	1.1e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
MAKJDLNK_00434	1.35e-165	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
MAKJDLNK_00435	8.52e-254	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
MAKJDLNK_00436	3.86e-149	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MAKJDLNK_00437	9e-294	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MAKJDLNK_00438	2.77e-249	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MAKJDLNK_00439	1.92e-203	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MAKJDLNK_00440	1.53e-207	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MAKJDLNK_00441	1.78e-139	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MAKJDLNK_00442	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
MAKJDLNK_00443	1.02e-178	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
MAKJDLNK_00444	2.31e-63	-	-	-	-	-	-	-	-
MAKJDLNK_00445	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MAKJDLNK_00446	1.31e-245	ampC	-	-	V	-	-	-	Beta-lactamase
MAKJDLNK_00447	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MAKJDLNK_00448	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MAKJDLNK_00449	1.02e-102	-	-	-	K	-	-	-	Winged helix-turn-helix DNA-binding
MAKJDLNK_00450	3.24e-10	-	-	-	-	-	-	-	-
MAKJDLNK_00452	1.55e-74	-	-	-	-	-	-	-	-
MAKJDLNK_00454	5.68e-168	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
MAKJDLNK_00455	5.46e-186	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MAKJDLNK_00456	9.18e-206	yvgN	-	-	S	-	-	-	Aldo keto reductase
MAKJDLNK_00457	1.27e-158	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
MAKJDLNK_00458	1.74e-111	-	-	-	K	-	-	-	GNAT family
MAKJDLNK_00460	4.08e-100	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MAKJDLNK_00461	2.34e-49	-	-	-	K	-	-	-	transcriptional regulator
MAKJDLNK_00462	2.81e-212	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MAKJDLNK_00463	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MAKJDLNK_00464	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MAKJDLNK_00465	1.14e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MAKJDLNK_00466	5.85e-169	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MAKJDLNK_00467	1.78e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MAKJDLNK_00468	3.51e-21	gntT	-	-	EG	-	-	-	gluconate transmembrane transporter activity
MAKJDLNK_00469	3.97e-62	-	-	-	-	-	-	-	-
MAKJDLNK_00470	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
MAKJDLNK_00471	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
MAKJDLNK_00472	2.71e-197	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MAKJDLNK_00473	1.65e-242	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MAKJDLNK_00474	3.68e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAKJDLNK_00475	5.44e-278	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
MAKJDLNK_00476	2.66e-310	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MAKJDLNK_00477	4.62e-249	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MAKJDLNK_00478	7.63e-155	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
MAKJDLNK_00479	1.32e-307	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MAKJDLNK_00480	3.78e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MAKJDLNK_00481	2.63e-305	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
MAKJDLNK_00482	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MAKJDLNK_00483	9.8e-09	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
MAKJDLNK_00484	1.5e-277	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MAKJDLNK_00485	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
MAKJDLNK_00486	2.15e-298	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MAKJDLNK_00488	4.91e-240	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MAKJDLNK_00490	5.66e-288	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MAKJDLNK_00491	1.05e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAKJDLNK_00492	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MAKJDLNK_00493	1.4e-27	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MAKJDLNK_00496	3.69e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MAKJDLNK_00497	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MAKJDLNK_00498	4.42e-307	yycH	-	-	S	-	-	-	YycH protein
MAKJDLNK_00499	5.86e-185	yycI	-	-	S	-	-	-	YycH protein
MAKJDLNK_00500	5.49e-197	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
MAKJDLNK_00501	9.52e-270	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
MAKJDLNK_00502	1.43e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MAKJDLNK_00503	3.03e-94	ywnA	-	-	K	-	-	-	Transcriptional regulator
MAKJDLNK_00504	2.68e-224	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
MAKJDLNK_00505	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
MAKJDLNK_00506	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
MAKJDLNK_00507	7.69e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
MAKJDLNK_00509	4.98e-20	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKJDLNK_00510	2.97e-244	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MAKJDLNK_00511	2.32e-234	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
MAKJDLNK_00512	2.3e-230	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MAKJDLNK_00513	3.41e-278	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MAKJDLNK_00514	1.15e-47	-	-	-	-	-	-	-	-
MAKJDLNK_00515	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
MAKJDLNK_00516	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MAKJDLNK_00517	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MAKJDLNK_00518	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MAKJDLNK_00519	1.26e-210	-	-	-	C	-	-	-	Aldo keto reductase
MAKJDLNK_00520	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
MAKJDLNK_00521	3.67e-86	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MAKJDLNK_00522	3.05e-242	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MAKJDLNK_00523	6.55e-166	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MAKJDLNK_00524	4.91e-56	-	-	-	K	-	-	-	transcriptional regulator
MAKJDLNK_00525	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
MAKJDLNK_00526	6.96e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
MAKJDLNK_00527	3.13e-126	-	-	-	-	-	-	-	-
MAKJDLNK_00528	1.01e-171	yaaA	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
MAKJDLNK_00529	3.04e-154	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MAKJDLNK_00530	1.02e-145	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
MAKJDLNK_00531	8.44e-128	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MAKJDLNK_00532	9.87e-203	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MAKJDLNK_00533	1.77e-298	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MAKJDLNK_00534	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
MAKJDLNK_00535	2.07e-116	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
MAKJDLNK_00536	7.76e-72	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
MAKJDLNK_00537	2.45e-41	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
MAKJDLNK_00538	5.26e-14	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
MAKJDLNK_00539	1.15e-230	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
MAKJDLNK_00540	1.75e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
MAKJDLNK_00541	6.74e-270	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MAKJDLNK_00542	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
MAKJDLNK_00543	1.67e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
MAKJDLNK_00544	2.58e-276	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MAKJDLNK_00545	2.06e-68	lysR	-	-	K	-	-	-	Transcriptional regulator
MAKJDLNK_00546	5.18e-17	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
MAKJDLNK_00547	5.38e-273	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
MAKJDLNK_00548	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
MAKJDLNK_00549	1.8e-271	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MAKJDLNK_00550	8.81e-202	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
MAKJDLNK_00551	1.53e-214	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
MAKJDLNK_00552	3.52e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MAKJDLNK_00553	8.22e-305	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MAKJDLNK_00554	1.52e-208	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MAKJDLNK_00555	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MAKJDLNK_00556	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
MAKJDLNK_00557	4.64e-36	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
MAKJDLNK_00558	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MAKJDLNK_00560	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MAKJDLNK_00561	1.06e-17	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MAKJDLNK_00562	3.15e-312	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MAKJDLNK_00563	3.88e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MAKJDLNK_00564	8.24e-71	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MAKJDLNK_00565	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
MAKJDLNK_00566	4.17e-237	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
MAKJDLNK_00567	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MAKJDLNK_00568	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MAKJDLNK_00569	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MAKJDLNK_00570	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MAKJDLNK_00571	8.93e-250	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MAKJDLNK_00572	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MAKJDLNK_00573	6.56e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
MAKJDLNK_00574	7.14e-111	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MAKJDLNK_00576	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MAKJDLNK_00577	3.97e-60	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MAKJDLNK_00578	6.48e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MAKJDLNK_00579	2.06e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MAKJDLNK_00580	2.41e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MAKJDLNK_00581	2.25e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
MAKJDLNK_00582	5.8e-248	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MAKJDLNK_00583	2.47e-74	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MAKJDLNK_00584	2.83e-202	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MAKJDLNK_00585	3.17e-186	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
MAKJDLNK_00586	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
MAKJDLNK_00587	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MAKJDLNK_00588	1.67e-221	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
MAKJDLNK_00589	8.55e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MAKJDLNK_00590	1.35e-203	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
MAKJDLNK_00591	2.08e-239	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MAKJDLNK_00592	1.17e-217	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
MAKJDLNK_00593	3.45e-305	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
MAKJDLNK_00594	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
MAKJDLNK_00595	8.37e-282	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
MAKJDLNK_00596	1.61e-274	arcT	-	-	E	-	-	-	Aminotransferase
MAKJDLNK_00597	1.68e-168	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
MAKJDLNK_00598	5.55e-143	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
MAKJDLNK_00599	3.65e-250	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MAKJDLNK_00601	3.83e-100	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MAKJDLNK_00602	1.32e-97	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
MAKJDLNK_00603	2.18e-218	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MAKJDLNK_00604	4.18e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MAKJDLNK_00605	6.22e-216	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
MAKJDLNK_00606	2.67e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MAKJDLNK_00607	1.32e-291	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MAKJDLNK_00608	3.46e-94	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MAKJDLNK_00609	1.13e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MAKJDLNK_00610	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
MAKJDLNK_00611	1.78e-203	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MAKJDLNK_00612	4.46e-180	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
MAKJDLNK_00613	1.55e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MAKJDLNK_00614	1.67e-117	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MAKJDLNK_00615	1.04e-224	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MAKJDLNK_00616	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
MAKJDLNK_00617	8.05e-149	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MAKJDLNK_00618	1.15e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MAKJDLNK_00619	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MAKJDLNK_00620	0.0	ydaO	-	-	E	-	-	-	amino acid
MAKJDLNK_00621	4.12e-50	-	-	-	-	-	-	-	-
MAKJDLNK_00622	5.69e-147	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
MAKJDLNK_00623	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
MAKJDLNK_00624	1.02e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
MAKJDLNK_00625	4.64e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MAKJDLNK_00626	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MAKJDLNK_00627	2.5e-258	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MAKJDLNK_00628	1.97e-70	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
MAKJDLNK_00629	4.15e-69	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
MAKJDLNK_00630	1.13e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MAKJDLNK_00631	3.09e-208	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MAKJDLNK_00632	9.09e-236	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MAKJDLNK_00633	3.11e-219	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MAKJDLNK_00634	1.06e-188	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
MAKJDLNK_00635	1.08e-289	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MAKJDLNK_00636	1.25e-240	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MAKJDLNK_00637	2.81e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
MAKJDLNK_00638	3.97e-231	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MAKJDLNK_00639	2.21e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MAKJDLNK_00640	5.62e-294	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MAKJDLNK_00641	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MAKJDLNK_00642	8.72e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
MAKJDLNK_00643	2.41e-07	-	-	-	-	-	-	-	-
MAKJDLNK_00644	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MAKJDLNK_00645	2.49e-166	-	-	-	F	-	-	-	NUDIX domain
MAKJDLNK_00646	2.47e-142	pncA	-	-	Q	-	-	-	Isochorismatase family
MAKJDLNK_00647	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MAKJDLNK_00648	8.07e-126	-	-	-	S	-	-	-	Pfam:DUF3816
MAKJDLNK_00649	9.48e-182	-	-	-	G	-	-	-	MucBP domain
MAKJDLNK_00650	1e-174	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MAKJDLNK_00651	4.44e-208	-	-	-	EG	-	-	-	EamA-like transporter family
MAKJDLNK_00652	6.84e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
MAKJDLNK_00655	9.46e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKJDLNK_00656	2.08e-84	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
MAKJDLNK_00657	2.18e-218	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MAKJDLNK_00658	4.85e-103	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
MAKJDLNK_00659	2.15e-266	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MAKJDLNK_00660	7.76e-189	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
MAKJDLNK_00661	3.67e-127	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
MAKJDLNK_00662	2.27e-120	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MAKJDLNK_00663	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MAKJDLNK_00664	1.5e-210	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
MAKJDLNK_00665	1.45e-216	yueF	-	-	S	-	-	-	AI-2E family transporter
MAKJDLNK_00666	6.59e-204	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
MAKJDLNK_00667	8.03e-10	-	-	-	-	-	-	-	-
MAKJDLNK_00668	2.2e-119	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
MAKJDLNK_00669	7.29e-71	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MAKJDLNK_00670	7.02e-245	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MAKJDLNK_00671	5.32e-44	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MAKJDLNK_00672	3.82e-36	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MAKJDLNK_00673	6.4e-197	-	-	-	C	-	-	-	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
MAKJDLNK_00674	1.96e-151	-	-	-	M	-	-	-	racemase activity, acting on amino acids and derivatives
MAKJDLNK_00675	0.0	-	-	-	E	ko:K03758	-	ko00000,ko02000	Amino acid permease
MAKJDLNK_00676	5.43e-256	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MAKJDLNK_00677	9.78e-114	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
MAKJDLNK_00678	4.24e-119	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
MAKJDLNK_00679	4.41e-110	-	-	-	S	-	-	-	Fic/DOC family
MAKJDLNK_00680	2.67e-125	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
MAKJDLNK_00681	1.09e-315	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
MAKJDLNK_00682	1.38e-236	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
MAKJDLNK_00683	1.89e-276	-	-	-	E	-	-	-	Aminotransferase
MAKJDLNK_00686	9.99e-161	-	-	-	S	-	-	-	Phage minor capsid protein 2
MAKJDLNK_00687	2.58e-209	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MAKJDLNK_00688	7.8e-124	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MAKJDLNK_00689	1.41e-06	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
MAKJDLNK_00691	1.45e-206	-	-	-	S	-	-	-	DUF218 domain
MAKJDLNK_00692	1.14e-213	yvgN	-	-	C	-	-	-	Aldo keto reductase
MAKJDLNK_00693	1.07e-104	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
MAKJDLNK_00694	1.57e-194	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
MAKJDLNK_00695	6.95e-301	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
MAKJDLNK_00696	3.78e-79	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MAKJDLNK_00697	7.19e-260	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
MAKJDLNK_00698	5.89e-231	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MAKJDLNK_00699	1.16e-284	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
MAKJDLNK_00700	2.03e-250	bdhA	1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4	-	C	ko:K00004,ko:K00008,ko:K00098	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
MAKJDLNK_00701	9.78e-231	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
MAKJDLNK_00702	7.95e-132	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
MAKJDLNK_00703	5.43e-180	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKJDLNK_00704	1.8e-138	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAKJDLNK_00705	2.84e-209	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
MAKJDLNK_00706	8.57e-92	ywnA	-	-	K	-	-	-	Transcriptional regulator
MAKJDLNK_00707	5.23e-97	-	-	-	O	ko:K07397	-	ko00000	OsmC-like protein
MAKJDLNK_00708	9.22e-96	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MAKJDLNK_00709	7.45e-28	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
MAKJDLNK_00710	8.35e-121	-	-	-	L	-	-	-	Probable transposase
MAKJDLNK_00711	1.38e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MAKJDLNK_00712	3.34e-68	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MAKJDLNK_00713	1.18e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MAKJDLNK_00714	2.48e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MAKJDLNK_00715	7.09e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MAKJDLNK_00716	5.57e-135	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
MAKJDLNK_00717	1.01e-173	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MAKJDLNK_00718	1.25e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MAKJDLNK_00719	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MAKJDLNK_00720	1.6e-128	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
MAKJDLNK_00721	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MAKJDLNK_00722	7.84e-264	yacL	-	-	S	-	-	-	domain protein
MAKJDLNK_00723	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MAKJDLNK_00724	3.55e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
MAKJDLNK_00725	6.52e-73	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
MAKJDLNK_00726	3.53e-158	-	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MAKJDLNK_00727	3.45e-144	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MAKJDLNK_00728	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MAKJDLNK_00729	3.23e-215	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MAKJDLNK_00730	9.09e-164	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MAKJDLNK_00731	1.25e-212	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
MAKJDLNK_00732	1.58e-241	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
MAKJDLNK_00733	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
MAKJDLNK_00735	2e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MAKJDLNK_00736	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
MAKJDLNK_00737	4.68e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MAKJDLNK_00738	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MAKJDLNK_00739	8.7e-166	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
MAKJDLNK_00740	1.56e-170	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MAKJDLNK_00741	4e-150	-	-	-	-	-	-	-	-
MAKJDLNK_00744	9.6e-212	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MAKJDLNK_00745	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
MAKJDLNK_00746	1.41e-239	-	-	-	D	-	-	-	nuclear chromosome segregation
MAKJDLNK_00747	2.45e-42	-	-	-	-	-	-	-	-
MAKJDLNK_00748	8.4e-56	-	-	-	K	-	-	-	Helix-turn-helix domain
MAKJDLNK_00749	1.4e-27	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MAKJDLNK_00750	3.8e-31	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
MAKJDLNK_00751	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
MAKJDLNK_00752	0.0	-	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	Putative ATP-dependent Lon protease
MAKJDLNK_00753	0.0	-	-	-	S	-	-	-	PglZ domain
MAKJDLNK_00754	1.67e-266	-	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
MAKJDLNK_00755	2.2e-245	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAKJDLNK_00756	0.0	-	-	-	V	-	-	-	Eco57I restriction-modification methylase
MAKJDLNK_00757	0.0	-	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
MAKJDLNK_00758	9.58e-132	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
MAKJDLNK_00759	2.73e-68	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
MAKJDLNK_00763	2.96e-132	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MAKJDLNK_00764	7.02e-22	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MAKJDLNK_00765	3.6e-99	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MAKJDLNK_00766	6.71e-214	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MAKJDLNK_00767	2e-240	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MAKJDLNK_00768	7.83e-206	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MAKJDLNK_00769	5.07e-261	-	-	-	-	-	-	-	-
MAKJDLNK_00770	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MAKJDLNK_00771	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MAKJDLNK_00773	1.02e-144	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
MAKJDLNK_00774	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MAKJDLNK_00775	2.08e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MAKJDLNK_00776	2.55e-143	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MAKJDLNK_00777	2.42e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MAKJDLNK_00778	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
MAKJDLNK_00779	6.64e-205	-	-	-	EG	-	-	-	EamA-like transporter family
MAKJDLNK_00780	1.41e-244	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
MAKJDLNK_00781	5.43e-190	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
MAKJDLNK_00782	4.14e-173	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
MAKJDLNK_00783	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
MAKJDLNK_00784	6.66e-115	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
MAKJDLNK_00785	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MAKJDLNK_00786	9.21e-216	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
MAKJDLNK_00787	1.29e-231	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
MAKJDLNK_00788	5.8e-271	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
MAKJDLNK_00789	5.29e-263	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MAKJDLNK_00790	2.27e-119	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MAKJDLNK_00791	2.64e-130	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MAKJDLNK_00792	9.79e-122	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MAKJDLNK_00793	2.23e-116	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MAKJDLNK_00794	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
MAKJDLNK_00795	2.16e-197	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
MAKJDLNK_00796	1.12e-213	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MAKJDLNK_00797	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MAKJDLNK_00798	1.25e-265	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MAKJDLNK_00799	3.26e-312	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MAKJDLNK_00800	4.85e-232	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MAKJDLNK_00801	5.83e-141	ycsI	-	-	S	-	-	-	Protein of unknown function (DUF1445)
MAKJDLNK_00802	4.13e-230	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MAKJDLNK_00803	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MAKJDLNK_00804	7.25e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MAKJDLNK_00805	1.2e-234	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MAKJDLNK_00806	8.31e-186	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MAKJDLNK_00807	1.41e-124	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
MAKJDLNK_00808	1.21e-48	-	-	-	-	-	-	-	-
MAKJDLNK_00809	8.36e-174	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAKJDLNK_00810	3.51e-154	-	-	-	U	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MAKJDLNK_00811	1.09e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
MAKJDLNK_00812	9.08e-71	-	-	-	-	-	-	-	-
MAKJDLNK_00813	7.01e-216	-	1.1.1.399, 1.1.1.95	-	CH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MAKJDLNK_00814	2.57e-104	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MAKJDLNK_00815	1.02e-186	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
MAKJDLNK_00816	2.44e-120	ymdB	-	-	S	-	-	-	Macro domain protein
MAKJDLNK_00817	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MAKJDLNK_00818	3e-291	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MAKJDLNK_00819	1.41e-59	-	-	-	-	-	-	-	-
MAKJDLNK_00820	7.17e-270	-	-	-	S	-	-	-	Putative metallopeptidase domain
MAKJDLNK_00821	1.35e-261	-	-	-	S	-	-	-	associated with various cellular activities
MAKJDLNK_00822	2e-150	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MAKJDLNK_00823	1.36e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
MAKJDLNK_00825	2.32e-161	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
MAKJDLNK_00826	7.49e-74	-	-	-	-	-	-	-	-
MAKJDLNK_00827	3.04e-140	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
MAKJDLNK_00828	6.55e-126	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MAKJDLNK_00829	1.68e-138	-	-	-	-	-	-	-	-
MAKJDLNK_00830	1.11e-35	-	-	-	-	-	-	-	-
MAKJDLNK_00831	4.26e-218	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
MAKJDLNK_00832	5.09e-312	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MAKJDLNK_00833	1.02e-60	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
MAKJDLNK_00834	7.5e-100	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MAKJDLNK_00835	2.78e-156	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKJDLNK_00836	1.41e-209	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MAKJDLNK_00837	1.85e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MAKJDLNK_00838	4.04e-111	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
MAKJDLNK_00839	1.04e-237	-	-	-	EGP	-	-	-	Major Facilitator
MAKJDLNK_00842	2.48e-135	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
MAKJDLNK_00843	7.6e-151	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MAKJDLNK_00844	1.43e-252	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
MAKJDLNK_00845	2.47e-13	-	-	-	K	-	-	-	transcriptional
MAKJDLNK_00846	6.02e-68	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
MAKJDLNK_00847	3.03e-74	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
MAKJDLNK_00848	2.24e-27	-	-	-	S	-	-	-	Protein conserved in bacteria
MAKJDLNK_00849	2.7e-126	ydeQ	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
MAKJDLNK_00850	1.44e-56	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MAKJDLNK_00851	1.51e-193	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
MAKJDLNK_00852	7.82e-239	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MAKJDLNK_00853	1.64e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
MAKJDLNK_00854	8.09e-122	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MAKJDLNK_00855	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MAKJDLNK_00856	1.3e-199	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MAKJDLNK_00857	8.64e-225	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MAKJDLNK_00858	9.56e-317	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MAKJDLNK_00859	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MAKJDLNK_00860	2.3e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAKJDLNK_00862	5.48e-70	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
MAKJDLNK_00863	5.34e-140	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MAKJDLNK_00864	2.06e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MAKJDLNK_00865	1.15e-299	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MAKJDLNK_00866	7.02e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MAKJDLNK_00867	2.71e-207	-	-	-	S	-	-	-	Tetratricopeptide repeat
MAKJDLNK_00868	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MAKJDLNK_00869	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MAKJDLNK_00870	1.34e-61	-	-	-	-	-	-	-	-
MAKJDLNK_00871	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MAKJDLNK_00872	1.12e-108	-	-	-	L	-	-	-	nuclease
MAKJDLNK_00873	3.27e-115	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
MAKJDLNK_00874	6.04e-45	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
MAKJDLNK_00875	1.93e-145	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MAKJDLNK_00876	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MAKJDLNK_00877	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MAKJDLNK_00878	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MAKJDLNK_00879	4.35e-284	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
MAKJDLNK_00880	1.77e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MAKJDLNK_00881	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MAKJDLNK_00882	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MAKJDLNK_00883	1.83e-198	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
MAKJDLNK_00884	4.99e-187	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MAKJDLNK_00885	2.64e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MAKJDLNK_00886	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
MAKJDLNK_00888	9.49e-317	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MAKJDLNK_00889	3.2e-264	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MAKJDLNK_00890	1.45e-46	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
MAKJDLNK_00891	3.04e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MAKJDLNK_00892	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MAKJDLNK_00893	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MAKJDLNK_00894	6.99e-305	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MAKJDLNK_00895	1.04e-245	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MAKJDLNK_00896	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
MAKJDLNK_00897	1.76e-109	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
MAKJDLNK_00898	1.5e-297	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MAKJDLNK_00899	1.28e-310	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
MAKJDLNK_00900	2.3e-186	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
MAKJDLNK_00901	2e-45	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
MAKJDLNK_00902	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
MAKJDLNK_00903	1.25e-31	-	-	-	S	-	-	-	Virus attachment protein p12 family
MAKJDLNK_00904	1.1e-201	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
MAKJDLNK_00905	1.27e-226	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MAKJDLNK_00906	2.41e-235	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MAKJDLNK_00907	9.06e-279	aspB3	-	-	E	-	-	-	DegT/DnrJ/EryC1/StrS aminotransferase family
MAKJDLNK_00908	2.61e-117	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MAKJDLNK_00909	2.37e-250	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
MAKJDLNK_00910	1.11e-300	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MAKJDLNK_00911	4.48e-131	-	-	-	-	-	-	-	-
MAKJDLNK_00912	1.88e-272	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MAKJDLNK_00913	7.56e-15	aroH	5.4.99.5	-	E	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
MAKJDLNK_00914	8.63e-274	-	-	-	G	-	-	-	Major Facilitator Superfamily
MAKJDLNK_00916	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
MAKJDLNK_00919	1.51e-194	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MAKJDLNK_00920	7.06e-58	-	-	-	GM	-	-	-	NAD(P)H-binding
MAKJDLNK_00921	6.38e-118	-	-	-	GM	-	-	-	NAD(P)H-binding
MAKJDLNK_00922	4.19e-203	-	-	-	S	-	-	-	Alpha beta hydrolase
MAKJDLNK_00923	5.61e-301	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
MAKJDLNK_00925	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
MAKJDLNK_00926	9.2e-57	-	-	-	-	-	-	-	-
MAKJDLNK_00928	3.17e-281	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MAKJDLNK_00929	2.49e-19	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
MAKJDLNK_00930	8.9e-62	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MAKJDLNK_00931	6.59e-76	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
MAKJDLNK_00932	2.01e-70	-	-	-	C	-	-	-	FMN binding
MAKJDLNK_00933	1.98e-258	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MAKJDLNK_00934	1.52e-137	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
MAKJDLNK_00935	9.63e-291	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MAKJDLNK_00936	1.14e-105	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MAKJDLNK_00937	2.75e-103	-	-	-	K	-	-	-	2 iron, 2 sulfur cluster binding
MAKJDLNK_00938	0.0	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
MAKJDLNK_00939	2.07e-282	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MAKJDLNK_00940	5.06e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MAKJDLNK_00941	4.92e-141	-	-	-	C	-	-	-	aldo keto reductase
MAKJDLNK_00942	3.72e-145	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
MAKJDLNK_00944	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MAKJDLNK_00945	1.06e-238	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MAKJDLNK_00946	1.25e-67	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
MAKJDLNK_00947	4.55e-74	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MAKJDLNK_00948	5.02e-124	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MAKJDLNK_00949	2.15e-11	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MAKJDLNK_00950	1.46e-71	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MAKJDLNK_00951	2.45e-267	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MAKJDLNK_00952	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MAKJDLNK_00953	9.76e-87	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MAKJDLNK_00954	2.84e-243	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MAKJDLNK_00955	6.7e-81	-	-	-	-	-	-	-	-
MAKJDLNK_00956	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
MAKJDLNK_00957	4.95e-216	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MAKJDLNK_00958	5.03e-232	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MAKJDLNK_00959	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MAKJDLNK_00960	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MAKJDLNK_00961	3.68e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MAKJDLNK_00962	1.15e-280	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MAKJDLNK_00963	1.09e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MAKJDLNK_00964	4.46e-181	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MAKJDLNK_00965	1.97e-277	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MAKJDLNK_00966	1.28e-253	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MAKJDLNK_00967	3.38e-293	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
MAKJDLNK_00968	2.29e-152	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
MAKJDLNK_00969	3.4e-163	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MAKJDLNK_00970	4.2e-202	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MAKJDLNK_00971	2.16e-302	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MAKJDLNK_00973	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MAKJDLNK_00974	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MAKJDLNK_00975	6.26e-215	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
MAKJDLNK_00976	7.32e-176	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
MAKJDLNK_00977	2.23e-89	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MAKJDLNK_00978	1.18e-182	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MAKJDLNK_00979	3.2e-131	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MAKJDLNK_00980	1.68e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MAKJDLNK_00981	2.03e-112	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MAKJDLNK_00982	3.83e-254	-	-	-	S	-	-	-	Helix-turn-helix domain
MAKJDLNK_00983	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
MAKJDLNK_00984	4.37e-76	-	-	-	M	-	-	-	Lysin motif
MAKJDLNK_00985	5.63e-154	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MAKJDLNK_00986	4.63e-275	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MAKJDLNK_00987	1.29e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MAKJDLNK_00988	2.65e-53	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MAKJDLNK_00989	2.52e-300	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
MAKJDLNK_00990	1.06e-210	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MAKJDLNK_00991	1.86e-285	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MAKJDLNK_00992	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MAKJDLNK_00993	5.32e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MAKJDLNK_00994	2.55e-121	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MAKJDLNK_00995	8.06e-141	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
MAKJDLNK_00996	1.34e-197	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
MAKJDLNK_00997	1.69e-277	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
MAKJDLNK_00998	1.4e-145	cat	2.3.1.79	-	S	ko:K00661,ko:K18234	-	ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
MAKJDLNK_00999	2.46e-217	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
MAKJDLNK_01000	2.85e-135	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
MAKJDLNK_01001	2.1e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MAKJDLNK_01002	1.03e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MAKJDLNK_01003	8.69e-182	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MAKJDLNK_01004	2.55e-212	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
MAKJDLNK_01005	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MAKJDLNK_01006	2.24e-198	-	-	-	D	-	-	-	DNA integration
MAKJDLNK_01007	9.3e-220	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MAKJDLNK_01008	5.26e-134	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MAKJDLNK_01009	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MAKJDLNK_01010	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MAKJDLNK_01011	2.53e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
MAKJDLNK_01012	4.6e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
MAKJDLNK_01013	7.86e-92	-	-	-	S	-	-	-	Belongs to the HesB IscA family
MAKJDLNK_01014	4.65e-100	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MAKJDLNK_01015	1.52e-41	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
MAKJDLNK_01016	4.07e-56	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
MAKJDLNK_01017	1.64e-105	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MAKJDLNK_01018	6.88e-312	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
MAKJDLNK_01019	3.75e-307	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
MAKJDLNK_01020	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
MAKJDLNK_01022	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MAKJDLNK_01023	1.38e-154	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
MAKJDLNK_01024	4.3e-312	yhjX	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
MAKJDLNK_01026	3.57e-22	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MAKJDLNK_01027	4.34e-25	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MAKJDLNK_01028	6.79e-183	-	-	-	EG	-	-	-	EamA-like transporter family
MAKJDLNK_01029	0.0	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
MAKJDLNK_01030	1.04e-26	-	-	-	S	-	-	-	Domain of unknown function (DUF1858)
MAKJDLNK_01031	3.62e-72	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MAKJDLNK_01032	5.4e-293	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MAKJDLNK_01033	1.5e-182	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MAKJDLNK_01034	3.08e-220	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MAKJDLNK_01035	2.02e-76	-	-	-	S	-	-	-	Flavodoxin
MAKJDLNK_01036	7.91e-95	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
MAKJDLNK_01037	2.34e-47	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
MAKJDLNK_01038	6.78e-249	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MAKJDLNK_01039	9.41e-278	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Major Facilitator Superfamily
MAKJDLNK_01040	2.36e-77	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MAKJDLNK_01041	4.73e-210	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
MAKJDLNK_01042	7.17e-172	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MAKJDLNK_01044	3.49e-217	-	-	-	H	-	-	-	geranyltranstransferase activity
MAKJDLNK_01045	1.2e-235	-	-	-	-	-	-	-	-
MAKJDLNK_01046	9.5e-52	-	-	-	-	-	-	-	-
MAKJDLNK_01047	1.83e-150	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
MAKJDLNK_01048	9.81e-241	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
MAKJDLNK_01049	8.62e-102	nreA	-	-	T	ko:K10851	ko02020,map02020	ko00000,ko00001	GAF domain
MAKJDLNK_01050	6.94e-54	-	-	-	-	-	-	-	-
MAKJDLNK_01051	7.14e-128	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MAKJDLNK_01052	1.11e-107	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MAKJDLNK_01053	8.99e-295	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
MAKJDLNK_01054	2.18e-112	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
MAKJDLNK_01055	6.23e-244	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
MAKJDLNK_01056	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MAKJDLNK_01057	0.0	-	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
MAKJDLNK_01058	2.15e-132	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	Nitrate reductase delta subunit
MAKJDLNK_01059	1.24e-163	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
MAKJDLNK_01060	6.87e-117	yejD	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	nucleoside 2-deoxyribosyltransferase
MAKJDLNK_01061	1.14e-37	-	-	-	EGP	-	-	-	Major Facilitator
MAKJDLNK_01062	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MAKJDLNK_01063	2.79e-69	-	-	-	S	-	-	-	Cupredoxin-like domain
MAKJDLNK_01064	1.07e-67	-	-	-	S	-	-	-	Cupredoxin-like domain
MAKJDLNK_01065	2.88e-226	-	-	-	-	-	-	-	-
MAKJDLNK_01066	6.98e-286	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MAKJDLNK_01067	1.15e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MAKJDLNK_01068	6.76e-308	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MAKJDLNK_01069	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MAKJDLNK_01070	1.32e-138	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MAKJDLNK_01071	3.94e-250	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MAKJDLNK_01072	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MAKJDLNK_01073	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MAKJDLNK_01074	4.87e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MAKJDLNK_01075	1.36e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MAKJDLNK_01076	6.13e-174	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MAKJDLNK_01077	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
MAKJDLNK_01078	1.45e-223	hrpQ	4.6.1.1	-	T	ko:K01768,ko:K03220,ko:K10914	ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111	ko00000,ko00001,ko00002,ko01000,ko02044,ko03000	histone H2A K63-linked ubiquitination
MAKJDLNK_01079	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MAKJDLNK_01080	1.74e-274	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MAKJDLNK_01081	3.36e-105	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MAKJDLNK_01082	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
MAKJDLNK_01083	4.91e-224	ydbI	-	-	K	-	-	-	AI-2E family transporter
MAKJDLNK_01084	4.7e-96	-	-	-	-	-	-	-	-
MAKJDLNK_01087	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MAKJDLNK_01088	1.72e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MAKJDLNK_01089	1.54e-279	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MAKJDLNK_01090	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MAKJDLNK_01091	3.28e-165	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MAKJDLNK_01092	1.65e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MAKJDLNK_01093	2.2e-215	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MAKJDLNK_01094	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MAKJDLNK_01095	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
MAKJDLNK_01096	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
MAKJDLNK_01097	5.82e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MAKJDLNK_01098	3.05e-159	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MAKJDLNK_01099	1.1e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MAKJDLNK_01100	2.17e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MAKJDLNK_01101	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MAKJDLNK_01102	1.68e-169	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MAKJDLNK_01103	1.29e-314	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MAKJDLNK_01104	5.61e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MAKJDLNK_01105	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MAKJDLNK_01106	6.81e-274	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MAKJDLNK_01107	5.45e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MAKJDLNK_01108	1.03e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MAKJDLNK_01110	1.65e-53	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
MAKJDLNK_01111	2.69e-311	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
MAKJDLNK_01112	1.08e-229	-	-	-	K	-	-	-	WYL domain
MAKJDLNK_01113	3.96e-89	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
MAKJDLNK_01114	1.72e-40	-	-	-	-	-	-	-	-
MAKJDLNK_01117	4.58e-85	-	-	-	-	-	-	-	-
MAKJDLNK_01118	8.21e-144	yicL	-	-	EG	-	-	-	EamA-like transporter family
MAKJDLNK_01119	7.21e-108	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
MAKJDLNK_01120	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MAKJDLNK_01121	1.65e-215	-	-	-	K	-	-	-	LysR substrate binding domain
MAKJDLNK_01122	1.41e-206	rssA	-	-	S	-	-	-	Phospholipase, patatin family
MAKJDLNK_01123	2.2e-272	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MAKJDLNK_01124	3.66e-236	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
MAKJDLNK_01125	3.45e-158	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MAKJDLNK_01126	9.62e-116	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
MAKJDLNK_01127	1.67e-249	flp	-	-	V	-	-	-	Beta-lactamase
MAKJDLNK_01128	1.95e-291	-	-	-	-	-	-	-	-
MAKJDLNK_01130	5.3e-207	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MAKJDLNK_01131	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MAKJDLNK_01132	4.23e-213	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
MAKJDLNK_01133	3.89e-209	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
MAKJDLNK_01134	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MAKJDLNK_01137	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
MAKJDLNK_01138	5.38e-19	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
MAKJDLNK_01140	4.88e-236	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
MAKJDLNK_01141	9.97e-103	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
MAKJDLNK_01142	1.29e-125	-	-	-	-	-	-	-	-
MAKJDLNK_01144	6.71e-110	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAKJDLNK_01146	2.1e-07	-	-	-	S	-	-	-	sequence-specific DNA binding
MAKJDLNK_01148	0.000452	-	-	-	S	-	-	-	Protein conserved in bacteria
MAKJDLNK_01159	5.73e-19	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MAKJDLNK_01166	1.27e-92	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
MAKJDLNK_01169	2.81e-43	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MAKJDLNK_01170	6.92e-33	-	-	-	L	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
MAKJDLNK_01172	2.53e-30	-	-	-	-	-	-	-	-
MAKJDLNK_01173	7.18e-170	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
MAKJDLNK_01174	5.7e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MAKJDLNK_01175	1.18e-196	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MAKJDLNK_01176	1.74e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MAKJDLNK_01177	1.28e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MAKJDLNK_01178	2.78e-158	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MAKJDLNK_01179	4.94e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MAKJDLNK_01180	3.08e-52	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MAKJDLNK_01181	1.52e-114	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MAKJDLNK_01182	2.22e-182	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MAKJDLNK_01183	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
MAKJDLNK_01184	6.59e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MAKJDLNK_01185	1.25e-107	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
MAKJDLNK_01186	1.03e-241	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
MAKJDLNK_01187	4.41e-176	casA	-	-	L	ko:K19123	-	ko00000,ko02048	the current gene model (or a revised gene model) may contain a frame shift
MAKJDLNK_01188	2.42e-53	-	-	-	S	ko:K19046	-	ko00000,ko02048	CRISPR-associated protein Cse2 (CRISPR_cse2)
MAKJDLNK_01189	1.43e-162	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CT1975-like protein
MAKJDLNK_01190	7.03e-83	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
MAKJDLNK_01191	2.37e-90	casE	-	-	S	ko:K19126	-	ko00000,ko02048	CRISPR_assoc
MAKJDLNK_01192	8.83e-160	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MAKJDLNK_01193	8.43e-100	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas2CT1978)
MAKJDLNK_01194	4.97e-59	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MAKJDLNK_01195	1.66e-119	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
MAKJDLNK_01196	1.9e-202	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MAKJDLNK_01197	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MAKJDLNK_01198	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MAKJDLNK_01199	1.18e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MAKJDLNK_01200	6.25e-268	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MAKJDLNK_01201	7.09e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
MAKJDLNK_01202	4.51e-148	-	-	-	S	-	-	-	(CBS) domain
MAKJDLNK_01203	7.98e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MAKJDLNK_01204	8.27e-252	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MAKJDLNK_01205	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MAKJDLNK_01206	2.47e-53	yabO	-	-	J	-	-	-	S4 domain protein
MAKJDLNK_01207	5.88e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MAKJDLNK_01208	1.65e-113	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
MAKJDLNK_01209	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MAKJDLNK_01210	5.21e-126	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MAKJDLNK_01211	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MAKJDLNK_01212	4.73e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MAKJDLNK_01213	5.32e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MAKJDLNK_01214	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MAKJDLNK_01215	9.16e-209	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
MAKJDLNK_01216	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
MAKJDLNK_01217	4.01e-154	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
MAKJDLNK_01218	1.35e-241	-	-	-	I	-	-	-	Alpha beta
MAKJDLNK_01219	7.04e-139	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MAKJDLNK_01220	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MAKJDLNK_01222	2.46e-216	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MAKJDLNK_01223	1.74e-187	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
MAKJDLNK_01224	2.85e-151	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
MAKJDLNK_01225	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MAKJDLNK_01226	3.98e-96	-	-	-	K	-	-	-	MerR HTH family regulatory protein
MAKJDLNK_01227	6.67e-77	-	-	-	-	-	-	-	-
MAKJDLNK_01228	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MAKJDLNK_01229	4.4e-282	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MAKJDLNK_01230	1.18e-28	elaA	-	-	S	ko:K02348	-	ko00000	acyltransferase COG2153
MAKJDLNK_01231	2.49e-110	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
MAKJDLNK_01232	6.41e-140	-	-	-	S	-	-	-	VIT family
MAKJDLNK_01233	1.79e-148	-	-	-	S	-	-	-	membrane
MAKJDLNK_01234	4.36e-209	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
MAKJDLNK_01235	2.51e-158	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
MAKJDLNK_01236	1.26e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
MAKJDLNK_01237	8.73e-50	-	-	-	S	-	-	-	Bacteriophage holin family
MAKJDLNK_01238	2.93e-85	-	-	-	S	-	-	-	Phage head-tail joining protein
MAKJDLNK_01239	2.17e-57	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MAKJDLNK_01240	4.15e-278	-	-	-	S	-	-	-	Phage capsid family
MAKJDLNK_01241	4.66e-156	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
MAKJDLNK_01242	6.79e-310	-	-	-	S	-	-	-	Phage portal protein
MAKJDLNK_01243	0.0	-	-	-	S	-	-	-	overlaps another CDS with the same product name
MAKJDLNK_01244	3.3e-39	-	-	-	S	-	-	-	Domain of unknown function (DUF5049)
MAKJDLNK_01245	7.39e-131	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
MAKJDLNK_01246	5.27e-280	-	-	-	KL	-	-	-	DNA methylase
MAKJDLNK_01247	6.51e-93	-	-	-	-	-	-	-	-
MAKJDLNK_01248	2.41e-111	-	-	-	-	-	-	-	-
MAKJDLNK_01249	9.22e-317	-	-	-	L	-	-	-	SNF2 family N-terminal domain
MAKJDLNK_01250	2.14e-62	-	-	-	S	-	-	-	VRR_NUC
MAKJDLNK_01251	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
MAKJDLNK_01252	3.05e-91	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
MAKJDLNK_01253	0.0	-	2.7.7.7	-	L	ko:K02334	-	ko00000,ko01000	DNA polymerase
MAKJDLNK_01254	2.71e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
MAKJDLNK_01255	1.48e-269	-	-	-	L	-	-	-	Protein of unknown function (DUF2800)
MAKJDLNK_01256	3.09e-54	-	-	-	-	-	-	-	-
MAKJDLNK_01257	2.18e-32	-	-	-	-	-	-	-	-
MAKJDLNK_01259	2.7e-37	-	-	-	-	-	-	-	-
MAKJDLNK_01260	8.53e-15	-	-	-	-	-	-	-	-
MAKJDLNK_01261	1.49e-11	-	-	-	L	ko:K02057	-	ko00000,ko00002,ko02000	ATPase involved in DNA repair
MAKJDLNK_01262	1.18e-39	-	-	-	M	-	-	-	PFAM Glycosyl transferase family 2
MAKJDLNK_01264	9.16e-28	lgtD	-	-	S	-	-	-	Glycosyltransferase like family 2
MAKJDLNK_01265	1.49e-114	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
MAKJDLNK_01266	4.74e-166	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
MAKJDLNK_01267	5.63e-178	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
MAKJDLNK_01268	2.75e-146	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
MAKJDLNK_01269	2.26e-168	epsB	-	-	M	-	-	-	biosynthesis protein
MAKJDLNK_01270	1.7e-216	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MAKJDLNK_01271	5.72e-263	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MAKJDLNK_01272	2.37e-175	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
MAKJDLNK_01273	8.67e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MAKJDLNK_01274	8.53e-41	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
MAKJDLNK_01275	5.29e-189	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MAKJDLNK_01276	5.7e-210	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MAKJDLNK_01277	5.01e-171	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
MAKJDLNK_01278	2.31e-185	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
MAKJDLNK_01279	2.56e-271	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
MAKJDLNK_01280	4.32e-17	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
MAKJDLNK_01281	2.82e-65	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MAKJDLNK_01282	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
MAKJDLNK_01283	1.56e-132	cadD	-	-	P	-	-	-	Cadmium resistance transporter
MAKJDLNK_01284	1.55e-151	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
MAKJDLNK_01285	2.41e-134	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MAKJDLNK_01286	2.52e-203	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MAKJDLNK_01287	4.53e-127	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MAKJDLNK_01288	4.59e-49	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
MAKJDLNK_01289	5.69e-87	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
MAKJDLNK_01290	7.95e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MAKJDLNK_01291	5.05e-146	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MAKJDLNK_01292	4.46e-184	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MAKJDLNK_01293	2.05e-179	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MAKJDLNK_01294	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MAKJDLNK_01295	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MAKJDLNK_01296	1.13e-118	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MAKJDLNK_01297	8.39e-47	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MAKJDLNK_01298	1.07e-41	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
MAKJDLNK_01300	4.74e-42	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
MAKJDLNK_01301	1.9e-42	-	-	-	I	ko:K01066	-	ko00000,ko01000	Esterase lipase
MAKJDLNK_01303	3.26e-128	-	-	-	S	-	-	-	integral membrane protein
MAKJDLNK_01304	8.4e-280	-	-	-	L	-	-	-	Probable transposase
MAKJDLNK_01305	5.81e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MAKJDLNK_01307	4.82e-72	-	-	-	-	-	-	-	-
MAKJDLNK_01308	1.11e-20	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
MAKJDLNK_01309	2.9e-181	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
MAKJDLNK_01310	2.59e-175	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MAKJDLNK_01311	4.23e-76	-	-	-	-	-	-	-	-
MAKJDLNK_01312	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MAKJDLNK_01313	3.12e-100	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MAKJDLNK_01314	5.22e-111	-	-	-	K	-	-	-	Transcriptional regulator
MAKJDLNK_01315	3.43e-280	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MAKJDLNK_01316	4.6e-271	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
MAKJDLNK_01317	6.31e-78	yxeM	-	-	ET	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MAKJDLNK_01318	1.03e-59	yxeL	-	-	K	-	-	-	acetyltransferase
MAKJDLNK_01319	1.2e-98	yxeN	-	-	U	ko:K02029,ko:K16959,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
MAKJDLNK_01320	6.15e-100	yxeO	-	-	E	ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MAKJDLNK_01321	8.5e-185	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
MAKJDLNK_01322	7.29e-215	-	4.3.2.2, 5.5.1.2	-	F	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
MAKJDLNK_01323	3.45e-107	-	-	-	S	-	-	-	MmgE/PrpD family
MAKJDLNK_01325	6.84e-147	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
MAKJDLNK_01326	5.52e-139	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
MAKJDLNK_01327	3.4e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAKJDLNK_01328	3.69e-197	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MAKJDLNK_01329	5.44e-176	-	-	-	IQ	-	-	-	KR domain
MAKJDLNK_01331	1.77e-244	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
MAKJDLNK_01332	6.72e-204	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
MAKJDLNK_01333	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MAKJDLNK_01334	1.95e-221	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
MAKJDLNK_01335	3.92e-217	-	-	-	G	-	-	-	Phosphotransferase enzyme family
MAKJDLNK_01336	4.44e-226	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
MAKJDLNK_01337	1.27e-249	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
MAKJDLNK_01338	1.39e-314	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MAKJDLNK_01339	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MAKJDLNK_01340	1.1e-165	-	-	-	F	-	-	-	glutamine amidotransferase
MAKJDLNK_01341	3.81e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MAKJDLNK_01342	1.52e-93	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
MAKJDLNK_01343	1.75e-228	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
MAKJDLNK_01344	8.34e-104	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MAKJDLNK_01345	4.42e-87	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
MAKJDLNK_01346	8.91e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MAKJDLNK_01347	5.3e-200	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MAKJDLNK_01348	3.59e-240	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MAKJDLNK_01349	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MAKJDLNK_01350	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MAKJDLNK_01351	1.21e-264	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MAKJDLNK_01352	3.14e-103	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
MAKJDLNK_01353	4.16e-127	-	-	-	K	-	-	-	Virulence activator alpha C-term
MAKJDLNK_01354	1.48e-119	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
MAKJDLNK_01356	2.05e-281	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
MAKJDLNK_01358	8.93e-185	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MAKJDLNK_01359	1.04e-194	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
MAKJDLNK_01360	8.17e-286	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
MAKJDLNK_01361	0.0	guaD	3.5.4.3	-	F	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
MAKJDLNK_01362	2.4e-277	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
MAKJDLNK_01364	1.89e-74	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphotyrosine protein phosphatase
MAKJDLNK_01365	8.72e-96	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MAKJDLNK_01366	1.63e-60	yrfB	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
MAKJDLNK_01367	1.47e-116	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
MAKJDLNK_01368	5.36e-171	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
MAKJDLNK_01369	4.15e-145	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKJDLNK_01370	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MAKJDLNK_01371	4.27e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF4256)
MAKJDLNK_01373	5.28e-132	-	-	-	K	-	-	-	DNA-templated transcription, initiation
MAKJDLNK_01374	2.73e-227	-	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MAKJDLNK_01375	5.93e-149	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
MAKJDLNK_01376	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
MAKJDLNK_01377	8.41e-235	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
MAKJDLNK_01378	3.77e-217	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
MAKJDLNK_01379	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MAKJDLNK_01380	1.64e-108	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
MAKJDLNK_01381	8.3e-141	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
MAKJDLNK_01382	1.35e-261	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
MAKJDLNK_01383	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
MAKJDLNK_01384	3.41e-232	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
MAKJDLNK_01385	6.23e-192	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MAKJDLNK_01386	2.77e-172	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKJDLNK_01388	3.09e-286	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
MAKJDLNK_01389	7.48e-298	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
MAKJDLNK_01390	9.26e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
MAKJDLNK_01391	1.9e-97	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	Domain of unknown function (DUF4162)
MAKJDLNK_01392	2.48e-71	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	transmembrane transport
MAKJDLNK_01394	1.71e-57	-	-	-	-	-	-	-	-
MAKJDLNK_01400	3.21e-20	-	-	-	D	-	-	-	nuclear chromosome segregation
MAKJDLNK_01401	2.48e-50	XK27_00515	-	-	D	-	-	-	Glucan-binding protein C
MAKJDLNK_01405	1.77e-234	-	-	-	-	-	-	-	-
MAKJDLNK_01406	1.01e-99	-	-	-	-	-	-	-	-
MAKJDLNK_01407	7.8e-44	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MAKJDLNK_01408	3.24e-61	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
MAKJDLNK_01409	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
MAKJDLNK_01410	1.69e-124	-	-	-	V	-	-	-	VanZ like family
MAKJDLNK_01411	2.95e-284	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MAKJDLNK_01412	4.56e-80	-	-	-	-	-	-	-	-
MAKJDLNK_01413	1.39e-233	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
MAKJDLNK_01414	2.34e-301	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
MAKJDLNK_01415	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MAKJDLNK_01416	4.81e-201	-	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
MAKJDLNK_01418	5.17e-100	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	ATPase, P-type transporting, HAD superfamily, subfamily IC
MAKJDLNK_01419	5.15e-246	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
MAKJDLNK_01420	0.0	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
MAKJDLNK_01421	2.36e-215	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
MAKJDLNK_01422	2.96e-265	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
MAKJDLNK_01423	3.66e-98	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
MAKJDLNK_01424	3.05e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
MAKJDLNK_01425	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
MAKJDLNK_01426	3.4e-116	-	-	-	GM	-	-	-	epimerase
MAKJDLNK_01427	9.84e-112	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
MAKJDLNK_01428	1.07e-198	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
MAKJDLNK_01429	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MAKJDLNK_01430	3.78e-167	-	-	-	-	-	-	-	-
MAKJDLNK_01431	4.23e-115	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MAKJDLNK_01432	3.81e-169	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
MAKJDLNK_01433	4.33e-191	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MAKJDLNK_01434	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
MAKJDLNK_01436	1.1e-163	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
MAKJDLNK_01437	6.29e-79	potE	-	-	E	-	-	-	Amino Acid
MAKJDLNK_01438	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MAKJDLNK_01439	1.78e-22	-	-	-	-	-	-	-	-
MAKJDLNK_01440	1.5e-149	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MAKJDLNK_01441	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAKJDLNK_01442	4.09e-131	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MAKJDLNK_01443	5.43e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
MAKJDLNK_01444	1.51e-235	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MAKJDLNK_01445	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
MAKJDLNK_01446	9.17e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
MAKJDLNK_01447	4.64e-129	dpsB	-	-	P	-	-	-	Belongs to the Dps family
MAKJDLNK_01448	3.81e-142	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
MAKJDLNK_01449	1.3e-110	-	-	-	-	-	-	-	-
MAKJDLNK_01450	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MAKJDLNK_01451	3.31e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
MAKJDLNK_01452	5.85e-192	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
MAKJDLNK_01453	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
MAKJDLNK_01454	2.1e-33	-	-	-	-	-	-	-	-
MAKJDLNK_01455	2.7e-162	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
MAKJDLNK_01456	2.03e-146	-	-	-	-	-	-	-	-
MAKJDLNK_01458	1.55e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MAKJDLNK_01459	6.08e-27	-	-	-	K	-	-	-	LytTr DNA-binding domain
MAKJDLNK_01460	1.11e-42	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
MAKJDLNK_01461	3.1e-77	-	-	-	P	-	-	-	Cadmium resistance transporter
MAKJDLNK_01462	8.83e-57	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MAKJDLNK_01464	5.09e-202	repA	-	-	S	-	-	-	Replication initiator protein A
MAKJDLNK_01466	1.28e-182	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
MAKJDLNK_01467	9.4e-121	-	-	-	L	-	-	-	Resolvase, N terminal domain
MAKJDLNK_01468	5.71e-274	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MAKJDLNK_01469	4.72e-151	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MAKJDLNK_01470	5.46e-161	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MAKJDLNK_01471	2.79e-174	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
MAKJDLNK_01472	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MAKJDLNK_01473	1.57e-313	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
MAKJDLNK_01474	3.45e-175	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
MAKJDLNK_01476	2.16e-98	uspA3	-	-	T	-	-	-	universal stress protein
MAKJDLNK_01477	6.25e-78	-	-	-	-	-	-	-	-
MAKJDLNK_01478	1.25e-09	-	-	-	-	-	-	-	-
MAKJDLNK_01479	1.92e-203	-	-	-	-	-	-	-	-
MAKJDLNK_01480	2.22e-98	-	-	-	K	-	-	-	Transcriptional regulator
MAKJDLNK_01481	5.3e-240	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MAKJDLNK_01482	9.46e-96	-	-	-	O	-	-	-	OsmC-like protein
MAKJDLNK_01483	3.36e-247	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
MAKJDLNK_01484	1.48e-117	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
MAKJDLNK_01485	2.79e-102	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MAKJDLNK_01486	1.47e-111	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
MAKJDLNK_01487	5.87e-94	-	-	-	M	-	-	-	LysM domain protein
MAKJDLNK_01488	1.43e-254	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
MAKJDLNK_01489	1.85e-301	-	-	-	F	ko:K03458	-	ko00000	Permease
MAKJDLNK_01490	1.99e-204	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
MAKJDLNK_01491	2.56e-145	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MAKJDLNK_01492	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
MAKJDLNK_01493	1.11e-145	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MAKJDLNK_01494	5.58e-182	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MAKJDLNK_01495	5.89e-20	ebrB	-	-	U	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MAKJDLNK_01496	1.6e-06	-	-	-	K	-	-	-	Transcriptional regulator
MAKJDLNK_01507	9.5e-260	potE	-	-	E	-	-	-	Amino Acid
MAKJDLNK_01508	1.65e-241	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MAKJDLNK_01509	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
MAKJDLNK_01510	2.57e-224	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MAKJDLNK_01511	1.49e-255	-	-	-	S	-	-	-	Domain of unknown function (DUF4432)
MAKJDLNK_01512	2.05e-147	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MAKJDLNK_01513	2.36e-217	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
MAKJDLNK_01514	3.74e-212	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MAKJDLNK_01515	8.61e-89	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MAKJDLNK_01516	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
MAKJDLNK_01517	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MAKJDLNK_01518	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MAKJDLNK_01519	4.03e-261	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
MAKJDLNK_01520	8.97e-95	-	-	-	F	-	-	-	Nudix hydrolase
MAKJDLNK_01521	9.61e-137	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
MAKJDLNK_01522	7.28e-110	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MAKJDLNK_01523	7.65e-10	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
MAKJDLNK_01524	5.54e-214	-	-	-	-	-	-	-	-
MAKJDLNK_01525	1.61e-250	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
MAKJDLNK_01526	4.94e-121	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
MAKJDLNK_01527	4.19e-315	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
MAKJDLNK_01528	4.58e-114	-	-	-	K	-	-	-	FR47-like protein
MAKJDLNK_01529	0.0	-	-	-	E	-	-	-	amino acid
MAKJDLNK_01530	2.05e-172	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
MAKJDLNK_01531	9.22e-268	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MAKJDLNK_01532	1.69e-296	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MAKJDLNK_01533	1.92e-155	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
MAKJDLNK_01534	2.5e-153	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
MAKJDLNK_01535	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MAKJDLNK_01536	5.52e-204	-	-	-	EG	-	-	-	EamA-like transporter family
MAKJDLNK_01537	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MAKJDLNK_01538	1.05e-174	-	-	-	IQ	-	-	-	dehydrogenase reductase
MAKJDLNK_01539	3.4e-136	-	-	-	K	-	-	-	acetyltransferase
MAKJDLNK_01540	1.61e-223	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MAKJDLNK_01541	8.4e-164	sptS	-	-	T	-	-	-	Histidine kinase
MAKJDLNK_01542	1.65e-101	dltr	-	-	K	-	-	-	response regulator
MAKJDLNK_01543	5.75e-147	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
MAKJDLNK_01544	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MAKJDLNK_01545	0.0	-	1.7.2.5	-	P	ko:K04561	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Cytochrome C and Quinol oxidase polypeptide I
MAKJDLNK_01546	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
MAKJDLNK_01548	2.24e-148	-	-	-	-	-	-	-	-
MAKJDLNK_01549	3.92e-47	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
MAKJDLNK_01550	1.76e-52	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
MAKJDLNK_01551	6.7e-72	-	-	-	K	-	-	-	Helix-turn-helix domain
MAKJDLNK_01552	6.28e-221	-	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
MAKJDLNK_01553	7.42e-07	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
MAKJDLNK_01554	5.81e-84	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
MAKJDLNK_01555	5.1e-66	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
MAKJDLNK_01556	1.29e-281	-	2.2.1.7	-	HI	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	1-deoxy-D-xylulose-5-phosphate synthase
MAKJDLNK_01557	8.31e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MAKJDLNK_01558	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKJDLNK_01559	1.39e-185	-	-	-	M	ko:K02004	-	ko00000,ko00002,ko02000	Membrane
MAKJDLNK_01560	5.02e-31	XK27_06785	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MAKJDLNK_01561	1.8e-130	-	-	-	K	-	-	-	Transcriptional regulator
MAKJDLNK_01562	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MAKJDLNK_01563	4.13e-304	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MAKJDLNK_01564	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MAKJDLNK_01565	1.13e-20	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MAKJDLNK_01566	2.16e-201	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
MAKJDLNK_01567	3.59e-10	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
MAKJDLNK_01568	2.36e-59	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
MAKJDLNK_01569	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
MAKJDLNK_01570	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MAKJDLNK_01571	2.08e-265	-	-	-	EGP	-	-	-	Major Facilitator
MAKJDLNK_01572	1.55e-274	ycsG	-	-	P	-	-	-	Natural resistance-associated macrophage protein
MAKJDLNK_01573	2.85e-163	-	-	-	S	ko:K07160	-	ko00000	LamB/YcsF family
MAKJDLNK_01574	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
MAKJDLNK_01575	1.86e-85	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MAKJDLNK_01576	1.42e-244	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
MAKJDLNK_01577	1.8e-171	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
MAKJDLNK_01578	2.31e-95	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MAKJDLNK_01579	4.35e-108	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
MAKJDLNK_01580	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
MAKJDLNK_01581	1.99e-121	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MAKJDLNK_01582	3.07e-135	-	-	-	NU	-	-	-	mannosyl-glycoprotein
MAKJDLNK_01583	5.59e-250	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
MAKJDLNK_01584	5.49e-22	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
MAKJDLNK_01585	1.15e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase
MAKJDLNK_01586	1.24e-160	-	-	-	S	-	-	-	Membrane
MAKJDLNK_01587	1.29e-298	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MAKJDLNK_01588	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MAKJDLNK_01589	5.62e-228	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MAKJDLNK_01590	6.08e-177	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MAKJDLNK_01591	3.07e-103	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
MAKJDLNK_01592	3.03e-106	usp5	-	-	T	-	-	-	universal stress protein
MAKJDLNK_01593	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MAKJDLNK_01594	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MAKJDLNK_01595	6.44e-22	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MAKJDLNK_01596	1.74e-152	yckA	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAKJDLNK_01597	1.45e-200	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
MAKJDLNK_01598	3.33e-140	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
MAKJDLNK_01599	7.61e-93	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
MAKJDLNK_01600	8.6e-93	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
MAKJDLNK_01601	1.27e-99	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MAKJDLNK_01602	1.05e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MAKJDLNK_01603	1.2e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
MAKJDLNK_01604	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MAKJDLNK_01605	4.36e-155	-	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
MAKJDLNK_01606	3.29e-50	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MAKJDLNK_01607	4.06e-60	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
MAKJDLNK_01608	2.89e-94	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
MAKJDLNK_01609	7.76e-53	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MAKJDLNK_01610	4.07e-22	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MAKJDLNK_01611	4.82e-189	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MAKJDLNK_01612	2.47e-40	-	-	-	IQ	-	-	-	reductase
MAKJDLNK_01613	2.98e-23	-	-	-	IQ	-	-	-	reductase
MAKJDLNK_01614	5.16e-15	fabG1	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MAKJDLNK_01620	4.69e-151	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
MAKJDLNK_01621	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
MAKJDLNK_01623	3.45e-199	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MAKJDLNK_01624	3.13e-149	-	-	-	I	-	-	-	phosphatase
MAKJDLNK_01625	8.17e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
MAKJDLNK_01626	1.11e-160	-	-	-	S	-	-	-	Putative threonine/serine exporter
MAKJDLNK_01627	7.55e-52	-	-	-	L	-	-	-	Integrase core domain
MAKJDLNK_01628	2.35e-160	-	-	-	O	-	-	-	Bacterial dnaA protein
MAKJDLNK_01629	2.88e-15	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MAKJDLNK_01630	2.45e-124	-	-	-	S	ko:K09705	-	ko00000	Cupin superfamily (DUF985)
MAKJDLNK_01631	1.24e-157	vanR	-	-	K	-	-	-	response regulator
MAKJDLNK_01632	7.28e-266	hpk31	-	-	T	-	-	-	Histidine kinase
MAKJDLNK_01633	1.68e-269	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MAKJDLNK_01634	2.19e-190	-	-	-	E	-	-	-	AzlC protein
MAKJDLNK_01635	2.22e-78	-	-	-	S	-	-	-	branched-chain amino acid
MAKJDLNK_01636	3.52e-126	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
MAKJDLNK_01637	1.42e-291	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
MAKJDLNK_01638	1.81e-180	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAKJDLNK_01639	8.57e-199	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MAKJDLNK_01640	3.25e-195	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MAKJDLNK_01641	1.13e-130	-	-	-	M	ko:K14193	ko05150,map05150	ko00000,ko00001	Iron Transport-associated domain
MAKJDLNK_01642	0.0	-	-	-	M	-	-	-	Iron Transport-associated domain
MAKJDLNK_01643	6.72e-106	-	-	-	-	-	-	-	-
MAKJDLNK_01644	8.58e-71	-	4.1.1.44	-	O	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MAKJDLNK_01645	5.03e-43	ydzE	-	-	EG	-	-	-	spore germination
MAKJDLNK_01646	1.55e-120	-	-	-	P	-	-	-	Cadmium resistance transporter
MAKJDLNK_01647	5.02e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
MAKJDLNK_01648	1.52e-203	is18	-	-	L	-	-	-	Integrase core domain
MAKJDLNK_01649	3.17e-60	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MAKJDLNK_01651	1.15e-86	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MAKJDLNK_01652	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MAKJDLNK_01653	2e-139	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
MAKJDLNK_01655	1.86e-193	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAKJDLNK_01657	4.89e-105	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
MAKJDLNK_01658	9.25e-54	-	-	-	-	-	-	-	-
MAKJDLNK_01659	1.04e-218	-	-	-	GK	-	-	-	ROK family
MAKJDLNK_01660	1.75e-165	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
MAKJDLNK_01661	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
MAKJDLNK_01662	6.33e-133	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MAKJDLNK_01663	2.51e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MAKJDLNK_01664	3.49e-72	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MAKJDLNK_01665	2.12e-70	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MAKJDLNK_01666	1.34e-74	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
MAKJDLNK_01667	1.2e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MAKJDLNK_01668	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MAKJDLNK_01669	2.14e-278	-	-	-	G	-	-	-	Transporter, major facilitator family protein
MAKJDLNK_01670	2.07e-262	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
MAKJDLNK_01671	4.58e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MAKJDLNK_01672	9.99e-216	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MAKJDLNK_01673	1.03e-121	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MAKJDLNK_01674	8.32e-66	-	-	-	-	-	-	-	-
MAKJDLNK_01675	1.79e-267	-	-	-	E	-	-	-	Major Facilitator Superfamily
MAKJDLNK_01676	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MAKJDLNK_01677	2.63e-99	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MAKJDLNK_01678	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MAKJDLNK_01679	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MAKJDLNK_01680	7.22e-153	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MAKJDLNK_01681	6.02e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MAKJDLNK_01702	1.12e-90	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MAKJDLNK_01703	7.24e-151	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MAKJDLNK_01704	1.69e-262	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MAKJDLNK_01705	1.2e-146	yjbH	-	-	Q	-	-	-	Thioredoxin
MAKJDLNK_01706	5.24e-159	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
MAKJDLNK_01707	9.49e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MAKJDLNK_01708	5.39e-221	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MAKJDLNK_01709	9.32e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
MAKJDLNK_01710	7.55e-206	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
MAKJDLNK_01711	2.01e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MAKJDLNK_01712	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MAKJDLNK_01713	4.5e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
MAKJDLNK_01714	9.82e-76	-	-	-	-	-	-	-	-
MAKJDLNK_01715	1.23e-105	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MAKJDLNK_01716	5.37e-221	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MAKJDLNK_01717	5.28e-31	ftsL	-	-	D	-	-	-	Cell division protein FtsL
MAKJDLNK_01718	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MAKJDLNK_01719	1.82e-226	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MAKJDLNK_01720	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MAKJDLNK_01721	2.06e-259	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MAKJDLNK_01722	5.43e-193	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MAKJDLNK_01723	4.88e-300	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MAKJDLNK_01724	1.23e-291	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MAKJDLNK_01725	4.13e-99	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MAKJDLNK_01726	7.27e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
MAKJDLNK_01727	2.49e-186	ylmH	-	-	S	-	-	-	S4 domain protein
MAKJDLNK_01728	6.19e-143	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
MAKJDLNK_01730	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MAKJDLNK_01731	9.99e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
MAKJDLNK_01732	5.21e-126	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MAKJDLNK_01734	3.26e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MAKJDLNK_01735	1.31e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
MAKJDLNK_01736	3.43e-283	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MAKJDLNK_01737	0.0	-	-	-	S	-	-	-	amidohydrolase
MAKJDLNK_01738	1.08e-218	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
MAKJDLNK_01739	1.51e-154	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
MAKJDLNK_01740	9.37e-159	-	-	-	S	-	-	-	repeat protein
MAKJDLNK_01741	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MAKJDLNK_01742	3.81e-228	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MAKJDLNK_01743	2.39e-98	-	-	-	P	-	-	-	ArsC family
MAKJDLNK_01744	8.46e-239	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
MAKJDLNK_01745	8.83e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MAKJDLNK_01746	6.12e-98	-	-	-	-	-	-	-	-
MAKJDLNK_01747	8.59e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MAKJDLNK_01748	1.55e-65	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
MAKJDLNK_01749	9.34e-176	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
MAKJDLNK_01750	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MAKJDLNK_01751	4.24e-270	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MAKJDLNK_01752	1.31e-63	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
MAKJDLNK_01753	1.27e-128	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
MAKJDLNK_01754	2.93e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MAKJDLNK_01755	1.38e-252	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MAKJDLNK_01756	1.47e-127	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
MAKJDLNK_01757	4.13e-114	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
MAKJDLNK_01758	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MAKJDLNK_01759	1.63e-236	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MAKJDLNK_01760	2.9e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MAKJDLNK_01761	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MAKJDLNK_01762	2.41e-235	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
MAKJDLNK_01763	3.45e-207	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
MAKJDLNK_01764	1.72e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MAKJDLNK_01765	8.45e-75	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MAKJDLNK_01766	1.01e-182	yceF	-	-	P	ko:K05794	-	ko00000	membrane
MAKJDLNK_01767	2.36e-214	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MAKJDLNK_01768	6.8e-220	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MAKJDLNK_01769	1.58e-301	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
MAKJDLNK_01770	1.24e-160	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
MAKJDLNK_01771	1.24e-305	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
MAKJDLNK_01772	4.76e-168	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
MAKJDLNK_01773	1.3e-301	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
MAKJDLNK_01774	1.33e-166	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MAKJDLNK_01775	3.27e-191	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
MAKJDLNK_01776	5.27e-237	hoxN	-	-	U	ko:K07241	-	ko00000,ko02000	High-affinity nickel-transport protein
MAKJDLNK_01777	3.67e-208	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	cog cog0286
MAKJDLNK_01778	8.28e-78	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain protein
MAKJDLNK_01781	8.12e-106	-	-	-	-	-	-	-	-
MAKJDLNK_01782	0.0	-	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
MAKJDLNK_01783	1.04e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
MAKJDLNK_01784	1.19e-61	-	-	-	D	-	-	-	Di-iron-containing protein involved in the repair of iron-sulfur clusters
MAKJDLNK_01785	9.02e-146	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
MAKJDLNK_01786	3.47e-149	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
MAKJDLNK_01787	2.75e-140	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MAKJDLNK_01788	1.38e-114	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MAKJDLNK_01789	9.03e-279	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MAKJDLNK_01790	9.95e-108	-	-	-	F	-	-	-	Hydrolase, NUDIX family
MAKJDLNK_01791	1.07e-271	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
MAKJDLNK_01792	0.0	fusA1	-	-	J	-	-	-	elongation factor G
MAKJDLNK_01793	3.83e-71	-	-	-	S	-	-	-	SNARE associated Golgi protein
MAKJDLNK_01794	9.53e-305	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MAKJDLNK_01795	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MAKJDLNK_01797	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MAKJDLNK_01798	2.16e-10	-	-	-	C	-	-	-	Domain of unknown function (DUF4145)
MAKJDLNK_01799	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MAKJDLNK_01800	3.01e-97	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Transcriptional regulator
MAKJDLNK_01801	3.78e-99	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
MAKJDLNK_01802	2.48e-151	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKJDLNK_01803	3.46e-225	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MAKJDLNK_01804	1.39e-93	crtM	2.5.1.32, 2.5.1.96, 2.5.1.99	-	I	ko:K02291,ko:K10208	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
MAKJDLNK_01805	6.93e-195	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAKJDLNK_01806	6.08e-107	uspA	-	-	T	-	-	-	universal stress protein
MAKJDLNK_01808	4.34e-299	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MAKJDLNK_01809	8.04e-111	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MAKJDLNK_01810	1.52e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
MAKJDLNK_01811	2.3e-173	-	-	-	S	-	-	-	Membrane
MAKJDLNK_01812	3.01e-190	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MAKJDLNK_01813	3.94e-89	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
MAKJDLNK_01814	6.62e-120	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
MAKJDLNK_01815	0.0	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
MAKJDLNK_01817	0.0	-	-	-	L	-	-	-	Transposase DDE domain
MAKJDLNK_01818	3.37e-25	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
MAKJDLNK_01822	3.68e-41	-	-	-	L	-	-	-	Initiator Replication protein
MAKJDLNK_01823	9.7e-118	-	-	-	M	-	-	-	Glycosyl transferase 4-like
MAKJDLNK_01825	2.22e-16	-	-	-	M	-	-	-	COG0438 Glycosyltransferase
MAKJDLNK_01826	3.51e-143	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MAKJDLNK_01827	4.95e-203	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
MAKJDLNK_01829	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MAKJDLNK_01830	8.8e-238	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
MAKJDLNK_01831	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MAKJDLNK_01832	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MAKJDLNK_01833	9.93e-65	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MAKJDLNK_01834	3.73e-231	camS	-	-	S	-	-	-	sex pheromone
MAKJDLNK_01835	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MAKJDLNK_01836	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MAKJDLNK_01837	7.47e-280	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MAKJDLNK_01838	3.89e-132	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MAKJDLNK_01839	2.33e-142	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
MAKJDLNK_01840	4.28e-178	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
MAKJDLNK_01841	1.03e-263	-	-	-	S	-	-	-	interspecies interaction between organisms
MAKJDLNK_01842	2.78e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MAKJDLNK_01843	5.57e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MAKJDLNK_01844	8.08e-188	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MAKJDLNK_01845	1.6e-178	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MAKJDLNK_01846	2.06e-201	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MAKJDLNK_01847	1.5e-193	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MAKJDLNK_01848	1.02e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MAKJDLNK_01849	3.48e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAKJDLNK_01850	8.02e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MAKJDLNK_01851	1.32e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MAKJDLNK_01852	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MAKJDLNK_01853	9.82e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MAKJDLNK_01854	2.16e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MAKJDLNK_01855	3.19e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MAKJDLNK_01856	3.5e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MAKJDLNK_01857	6.96e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MAKJDLNK_01858	3.59e-113	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MAKJDLNK_01859	5.55e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MAKJDLNK_01860	2.05e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MAKJDLNK_01861	7.64e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MAKJDLNK_01862	2.46e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MAKJDLNK_01863	1.75e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MAKJDLNK_01864	1.28e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MAKJDLNK_01865	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MAKJDLNK_01866	1.29e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MAKJDLNK_01867	1.35e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MAKJDLNK_01868	2.78e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MAKJDLNK_01869	3.43e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MAKJDLNK_01870	2.63e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MAKJDLNK_01871	1.51e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MAKJDLNK_01872	3.32e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MAKJDLNK_01873	2.76e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MAKJDLNK_01874	1.56e-137	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MAKJDLNK_01875	5.89e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MAKJDLNK_01876	3.14e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MAKJDLNK_01877	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MAKJDLNK_01878	4.15e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MAKJDLNK_01879	3.58e-93	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MAKJDLNK_01880	1.99e-39	pilD	3.4.23.43	-	NOU	ko:K02236,ko:K02506,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	aspartic-type endopeptidase activity
MAKJDLNK_01881	3.02e-275	-	-	-	-	-	-	-	-
MAKJDLNK_01882	2.92e-173	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
MAKJDLNK_01883	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAKJDLNK_01884	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAKJDLNK_01885	8.51e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MAKJDLNK_01886	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MAKJDLNK_01887	6.36e-103	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
MAKJDLNK_01888	7.92e-247	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MAKJDLNK_01889	4.84e-170	XK27_07210	-	-	S	-	-	-	B3 4 domain
MAKJDLNK_01890	4.27e-154	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
MAKJDLNK_01891	2.75e-42	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Hexapeptide repeat of succinyl-transferase
MAKJDLNK_01894	1.27e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MAKJDLNK_01895	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MAKJDLNK_01896	9.45e-317	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MAKJDLNK_01897	7.87e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
MAKJDLNK_01898	1.14e-58	yodA	-	-	S	-	-	-	Tautomerase enzyme
MAKJDLNK_01899	6.59e-17	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
MAKJDLNK_01900	1.84e-155	pnb	-	-	C	-	-	-	nitroreductase
MAKJDLNK_01901	9.46e-106	-	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
MAKJDLNK_01902	1.69e-99	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MAKJDLNK_01903	1.47e-30	-	-	-	C	-	-	-	reductase
MAKJDLNK_01904	1.68e-57	-	-	-	C	-	-	-	Aldo keto reductase
MAKJDLNK_01907	7.43e-08	-	-	-	C	-	-	-	Aldo/keto reductase family
MAKJDLNK_01908	1.2e-175	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MAKJDLNK_01909	9.22e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
MAKJDLNK_01910	2.39e-254	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MAKJDLNK_01911	2.09e-215	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MAKJDLNK_01912	5.7e-199	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
MAKJDLNK_01913	4.74e-166	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MAKJDLNK_01914	1.27e-220	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MAKJDLNK_01915	6.26e-138	-	-	-	L	-	-	-	Integrase
MAKJDLNK_01916	1.51e-88	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MAKJDLNK_01917	4.44e-58	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MAKJDLNK_01918	5.91e-80	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MAKJDLNK_01919	4.1e-48	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
MAKJDLNK_01920	9.16e-08	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MAKJDLNK_01921	6.97e-204	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MAKJDLNK_01922	1.96e-91	-	-	-	-	-	-	-	-
MAKJDLNK_01923	1.17e-09	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MAKJDLNK_01924	4.54e-301	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
MAKJDLNK_01925	4.01e-44	-	-	-	-	-	-	-	-
MAKJDLNK_01926	0.0	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
MAKJDLNK_01927	0.0	-	-	-	L	-	-	-	Recombinase
MAKJDLNK_01928	8.23e-23	-	2.1.1.303	-	K	ko:K04096,ko:K20421	ko01059,ko01130,map01059,map01130	ko00000,ko00001,ko00002,ko01000	DNA-binding transcription factor activity
MAKJDLNK_01930	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MAKJDLNK_01931	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
MAKJDLNK_01932	2.06e-51	-	-	-	L	-	-	-	Probable transposase
MAKJDLNK_01933	1.02e-32	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
MAKJDLNK_01934	5.19e-55	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
MAKJDLNK_01935	1.53e-87	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MAKJDLNK_01936	2.07e-71	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MAKJDLNK_01937	3.14e-20	-	-	-	C	-	-	-	Flavodoxin
MAKJDLNK_01938	2.39e-28	-	-	-	GM	-	-	-	NmrA-like family
MAKJDLNK_01939	5.08e-14	-	-	-	S	-	-	-	NAD(P)H dehydrogenase (quinone) activity
MAKJDLNK_01940	2.49e-276	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
MAKJDLNK_01941	1.69e-195	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, C-terminal domain
MAKJDLNK_01942	2.36e-51	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MAKJDLNK_01943	1.09e-186	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MAKJDLNK_01944	1.21e-54	-	-	-	-	-	-	-	-
MAKJDLNK_01945	5.57e-103	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MAKJDLNK_01946	1.93e-270	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MAKJDLNK_01948	5.3e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
MAKJDLNK_01949	1.34e-232	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
MAKJDLNK_01950	1.37e-187	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MAKJDLNK_01951	9.04e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
MAKJDLNK_01952	3.81e-142	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MAKJDLNK_01953	4.86e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAKJDLNK_01954	1.65e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MAKJDLNK_01955	4.68e-298	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
MAKJDLNK_01956	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
MAKJDLNK_01957	4.68e-151	-	-	-	S	-	-	-	Helix-turn-helix domain
MAKJDLNK_01958	1.79e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MAKJDLNK_01959	1.62e-293	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MAKJDLNK_01960	1.36e-245	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MAKJDLNK_01961	2.27e-305	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MAKJDLNK_01962	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MAKJDLNK_01963	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MAKJDLNK_01964	1.77e-135	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MAKJDLNK_01965	3.61e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MAKJDLNK_01966	5.14e-225	-	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	queuine tRNA-ribosyltransferase activity
MAKJDLNK_01967	9.08e-68	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MAKJDLNK_01968	3.41e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
MAKJDLNK_01969	8.44e-301	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MAKJDLNK_01970	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MAKJDLNK_01971	1.06e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MAKJDLNK_01972	4.97e-97	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MAKJDLNK_01973	3.99e-55	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MAKJDLNK_01974	3.2e-211	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MAKJDLNK_01975	2.23e-119	cvpA	-	-	S	-	-	-	Colicin V production protein
MAKJDLNK_01976	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MAKJDLNK_01977	1.66e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MAKJDLNK_01978	2.17e-285	-	-	-	P	-	-	-	Chloride transporter, ClC family
MAKJDLNK_01979	3.39e-121	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MAKJDLNK_01980	4.3e-188	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MAKJDLNK_01981	1.53e-139	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MAKJDLNK_01982	3.89e-122	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
MAKJDLNK_01983	7.14e-193	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MAKJDLNK_01984	3.54e-199	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
MAKJDLNK_01985	5.14e-68	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MAKJDLNK_01986	4.62e-92	-	-	-	-	-	-	-	-
MAKJDLNK_01987	1.08e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MAKJDLNK_01988	5.94e-238	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MAKJDLNK_01989	6.95e-182	-	-	-	-	-	-	-	-
MAKJDLNK_01990	5.01e-172	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
MAKJDLNK_01991	6.81e-123	-	-	-	M	-	-	-	PFAM NLP P60 protein
MAKJDLNK_01992	1.22e-180	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
MAKJDLNK_01993	3.47e-81	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
MAKJDLNK_01994	1.09e-227	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
MAKJDLNK_01995	4.31e-212	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
MAKJDLNK_01996	8.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
MAKJDLNK_02001	2.51e-202	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
MAKJDLNK_02002	9.57e-287	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MAKJDLNK_02003	2.73e-147	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MAKJDLNK_02004	9.43e-127	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
MAKJDLNK_02005	1.01e-182	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MAKJDLNK_02006	7.86e-20	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
MAKJDLNK_02007	8.3e-142	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
MAKJDLNK_02008	6.02e-107	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MAKJDLNK_02009	1.02e-69	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
MAKJDLNK_02010	3.97e-77	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MAKJDLNK_02011	1.47e-99	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Cellulose biosynthesis protein BcsQ
MAKJDLNK_02012	2.21e-144	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MAKJDLNK_02013	9.14e-155	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MAKJDLNK_02014	5.57e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MAKJDLNK_02015	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
MAKJDLNK_02016	8.34e-101	-	-	-	-	-	-	-	-
MAKJDLNK_02017	6.45e-06	-	-	-	UW	-	-	-	Tetratricopeptide repeat
MAKJDLNK_02018	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
MAKJDLNK_02019	6.6e-110	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MAKJDLNK_02020	9.59e-34	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MAKJDLNK_02021	1.84e-62	-	-	-	U	ko:K05340	-	ko00000,ko02000	ribose uptake protein RbsU
MAKJDLNK_02022	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
MAKJDLNK_02023	1.88e-135	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
MAKJDLNK_02024	1.37e-62	-	-	-	L	-	-	-	ATPase involved in DNA repair
MAKJDLNK_02025	1.46e-35	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MAKJDLNK_02026	7.31e-93	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
MAKJDLNK_02027	1.66e-34	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Type I restriction-modification system R subunit
MAKJDLNK_02028	8.52e-06	-	-	-	-	-	-	-	-
MAKJDLNK_02029	0.00021	-	-	-	G	-	-	-	Belongs to the peptidase S8 family
MAKJDLNK_02030	2.24e-113	-	-	-	-	-	-	-	-
MAKJDLNK_02031	3.37e-96	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
MAKJDLNK_02032	1.19e-41	-	-	-	S	-	-	-	Transglycosylase associated protein
MAKJDLNK_02033	4.74e-23	-	-	-	-	-	-	-	-
MAKJDLNK_02034	8.92e-160	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
MAKJDLNK_02035	3.02e-61	-	-	-	L	-	-	-	MULE transposase domain
MAKJDLNK_02036	5.24e-186	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MAKJDLNK_02037	0.0	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MAKJDLNK_02038	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
MAKJDLNK_02039	7.54e-210	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
MAKJDLNK_02040	3.36e-61	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
MAKJDLNK_02041	1.38e-251	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MAKJDLNK_02042	1.79e-268	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
MAKJDLNK_02043	2.11e-223	citR	-	-	K	-	-	-	sugar-binding domain protein
MAKJDLNK_02044	1.06e-312	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MAKJDLNK_02045	1.98e-211	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MAKJDLNK_02046	2.57e-274	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MAKJDLNK_02047	3.78e-282	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MAKJDLNK_02048	1.01e-116	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
MAKJDLNK_02049	1.43e-233	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
MAKJDLNK_02050	1.08e-289	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
MAKJDLNK_02051	1.95e-99	mleR	-	-	K	-	-	-	LysR family
MAKJDLNK_02052	6.99e-33	-	-	-	I	ko:K01066	-	ko00000,ko01000	esterase
MAKJDLNK_02053	9.97e-17	nlhH_1	-	-	I	ko:K01066	-	ko00000,ko01000	acetylesterase activity
MAKJDLNK_02054	1.87e-139	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MAKJDLNK_02055	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MAKJDLNK_02056	2.75e-248	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
MAKJDLNK_02057	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MAKJDLNK_02058	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
MAKJDLNK_02059	1.71e-211	-	-	-	K	-	-	-	LysR substrate binding domain
MAKJDLNK_02060	2.72e-212	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
MAKJDLNK_02061	2.74e-144	-	-	-	-	-	-	-	-
MAKJDLNK_02063	0.0	potE	-	-	E	-	-	-	Amino Acid
MAKJDLNK_02064	3.77e-217	-	-	-	V	-	-	-	Beta-lactamase enzyme family
MAKJDLNK_02065	6.99e-285	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MAKJDLNK_02066	7.4e-126	-	-	-	-	-	-	-	-
MAKJDLNK_02067	7.4e-254	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
MAKJDLNK_02068	4.4e-138	-	-	-	I	-	-	-	PAP2 superfamily
MAKJDLNK_02069	5.37e-72	-	-	-	S	-	-	-	MazG-like family
MAKJDLNK_02070	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MAKJDLNK_02071	2.72e-93	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
MAKJDLNK_02072	2.79e-125	-	-	-	K	-	-	-	transcriptional regulator
MAKJDLNK_02073	2.87e-209	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MAKJDLNK_02074	3.51e-80	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MAKJDLNK_02078	8.11e-52	-	-	-	S	-	-	-	Cytochrome B5
MAKJDLNK_02079	1.62e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MAKJDLNK_02080	7.07e-273	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
MAKJDLNK_02081	1.28e-101	-	-	-	M	-	-	-	Glycosyl transferase 4-like
MAKJDLNK_02082	0.0	dld	1.1.5.12	-	C	ko:K03777	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-lactate dehydrogenase, membrane binding
MAKJDLNK_02083	2.03e-193	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
MAKJDLNK_02084	5.74e-249	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MAKJDLNK_02085	1.27e-114	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
MAKJDLNK_02086	2.16e-45	epsB	-	-	M	-	-	-	biosynthesis protein
MAKJDLNK_02087	2.21e-114	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MAKJDLNK_02088	8.54e-63	-	-	-	L	-	-	-	Helix-turn-helix domain
MAKJDLNK_02089	1.39e-232	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MAKJDLNK_02090	1.65e-45	epsB	-	-	M	-	-	-	biosynthesis protein
MAKJDLNK_02091	4.27e-81	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein