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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
DIFHKINB_00002	1.75e-296	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
DIFHKINB_00003	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
DIFHKINB_00004	1.41e-93	-	-	-	-	-	-	-	-
DIFHKINB_00005	6.11e-129	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
DIFHKINB_00006	0.0	-	-	-	S	-	-	-	TerB-C domain
DIFHKINB_00007	0.0	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
DIFHKINB_00008	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
DIFHKINB_00009	5.12e-243	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
DIFHKINB_00010	1.45e-313	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
DIFHKINB_00011	1.53e-210	yvgN	-	-	C	-	-	-	Aldo keto reductase
DIFHKINB_00013	7.35e-198	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
DIFHKINB_00014	1.7e-122	-	-	-	K	-	-	-	acetyltransferase
DIFHKINB_00015	1.85e-80	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
DIFHKINB_00016	1.83e-175	-	-	-	S	-	-	-	Putative ABC-transporter type IV
DIFHKINB_00017	8.5e-171	-	-	-	M	-	-	-	LysM domain protein
DIFHKINB_00018	7.37e-151	-	-	-	M	-	-	-	LysM domain protein
DIFHKINB_00020	7.78e-80	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
DIFHKINB_00021	1.33e-196	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
DIFHKINB_00022	8.54e-21	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
DIFHKINB_00024	1.43e-187	-	-	-	K	-	-	-	SIS domain
DIFHKINB_00025	1.53e-214	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
DIFHKINB_00028	1.44e-69	XK27_05625	-	-	P	-	-	-	Rhodanese Homology Domain
DIFHKINB_00029	2.15e-246	-	-	-	-	-	-	-	-
DIFHKINB_00030	6.31e-159	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
DIFHKINB_00031	2.31e-87	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
DIFHKINB_00032	1.75e-182	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
DIFHKINB_00033	4.33e-260	-	-	-	M	-	-	-	Glycosyl transferases group 1
DIFHKINB_00034	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
DIFHKINB_00035	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DIFHKINB_00036	6.16e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
DIFHKINB_00037	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
DIFHKINB_00038	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
DIFHKINB_00039	1.29e-189	-	-	-	-	-	-	-	-
DIFHKINB_00040	1.79e-292	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
DIFHKINB_00041	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
DIFHKINB_00042	7.2e-174	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
DIFHKINB_00043	8.17e-112	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
DIFHKINB_00045	4.37e-131	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
DIFHKINB_00046	3.07e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
DIFHKINB_00047	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
DIFHKINB_00048	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DIFHKINB_00049	4.64e-265	camS	-	-	S	-	-	-	sex pheromone
DIFHKINB_00050	1.29e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DIFHKINB_00051	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DIFHKINB_00052	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DIFHKINB_00053	1.86e-215	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
DIFHKINB_00055	1.51e-194	-	-	-	S	-	-	-	hydrolase
DIFHKINB_00056	1.61e-49	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
DIFHKINB_00057	7.5e-29	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
DIFHKINB_00058	4.58e-161	-	-	-	L	-	-	-	Helix-turn-helix domain
DIFHKINB_00059	5.03e-122	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
DIFHKINB_00060	1.19e-113	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
DIFHKINB_00061	3.15e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
DIFHKINB_00062	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
DIFHKINB_00063	3.27e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
DIFHKINB_00064	5.56e-183	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
DIFHKINB_00065	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DIFHKINB_00066	1.8e-123	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
DIFHKINB_00067	1.36e-209	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
DIFHKINB_00068	2.12e-309	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
DIFHKINB_00069	3.41e-168	spaF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
DIFHKINB_00070	6.34e-156	-	-	-	S	ko:K01992,ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
DIFHKINB_00071	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DIFHKINB_00072	8.45e-68	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
DIFHKINB_00073	2.76e-32	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DIFHKINB_00074	0.0	-	-	-	L	-	-	-	Recombinase
DIFHKINB_00075	0.0	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
DIFHKINB_00076	2.08e-37	-	-	-	-	-	-	-	-
DIFHKINB_00077	1.51e-184	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
DIFHKINB_00078	5.95e-92	-	-	-	S	-	-	-	Bacteriophage holin family
DIFHKINB_00079	1.29e-88	-	-	-	S	-	-	-	Phage head-tail joining protein
DIFHKINB_00080	3.08e-57	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
DIFHKINB_00081	7.49e-281	-	-	-	S	-	-	-	Phage capsid family
DIFHKINB_00082	4.66e-156	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
DIFHKINB_00083	2.37e-310	-	-	-	S	-	-	-	Phage portal protein
DIFHKINB_00084	0.0	-	-	-	S	-	-	-	overlaps another CDS with the same product name
DIFHKINB_00085	8.38e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF5049)
DIFHKINB_00086	7.24e-147	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
DIFHKINB_00087	9.68e-292	-	-	-	KL	-	-	-	DNA methylase
DIFHKINB_00088	3.28e-128	-	-	-	-	-	-	-	-
DIFHKINB_00089	1.45e-112	-	-	-	-	-	-	-	-
DIFHKINB_00090	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
DIFHKINB_00091	3.57e-61	-	-	-	S	-	-	-	VRR_NUC
DIFHKINB_00092	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
DIFHKINB_00093	1.62e-78	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
DIFHKINB_00094	0.0	-	2.7.7.7	-	L	ko:K02334	-	ko00000,ko01000	DNA polymerase
DIFHKINB_00095	6.73e-126	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
DIFHKINB_00096	4.45e-255	-	-	-	L	-	-	-	Protein of unknown function (DUF2800)
DIFHKINB_00097	5.86e-33	-	-	-	-	-	-	-	-
DIFHKINB_00098	4.61e-30	-	-	-	-	-	-	-	-
DIFHKINB_00101	2.63e-135	-	-	-	F	-	-	-	helicase superfamily c-terminal domain
DIFHKINB_00102	3.94e-30	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
DIFHKINB_00103	1.69e-97	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
DIFHKINB_00104	7.24e-130	-	-	-	L	-	-	-	restriction endonuclease
DIFHKINB_00105	0.0	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
DIFHKINB_00106	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
DIFHKINB_00108	2.11e-253	flp	-	-	V	-	-	-	Beta-lactamase
DIFHKINB_00109	2.08e-196	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Belongs to the aminoglycoside phosphotransferase family
DIFHKINB_00110	1.88e-62	-	-	-	-	-	-	-	-
DIFHKINB_00111	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
DIFHKINB_00113	1.07e-207	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
DIFHKINB_00114	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
DIFHKINB_00115	3.16e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
DIFHKINB_00116	5.64e-295	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
DIFHKINB_00117	0.0	yhaN	-	-	L	-	-	-	AAA domain
DIFHKINB_00118	1.3e-238	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
DIFHKINB_00119	1.02e-201	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DIFHKINB_00120	2.42e-72	-	-	-	S	-	-	-	YtxH-like protein
DIFHKINB_00121	4.48e-90	-	-	-	-	-	-	-	-
DIFHKINB_00122	1.01e-100	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
DIFHKINB_00123	3.26e-173	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DIFHKINB_00124	3.63e-289	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
DIFHKINB_00125	3.87e-161	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DIFHKINB_00126	1.34e-53	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
DIFHKINB_00127	3.11e-19	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
DIFHKINB_00128	2.48e-70	ytpP	-	-	CO	-	-	-	Thioredoxin
DIFHKINB_00129	6.18e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DIFHKINB_00130	3.2e-121	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
DIFHKINB_00131	0.0	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
DIFHKINB_00132	2.92e-231	asnA2	3.5.1.1	-	E	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
DIFHKINB_00133	8.76e-121	-	-	-	S	-	-	-	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)
DIFHKINB_00134	1.23e-249	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DIFHKINB_00135	7.5e-153	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
DIFHKINB_00136	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
DIFHKINB_00137	5.75e-98	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
DIFHKINB_00138	1.92e-17	-	-	-	-	-	-	-	-
DIFHKINB_00139	6.53e-90	-	-	-	K	-	-	-	Transcriptional regulator
DIFHKINB_00140	4.61e-284	-	-	-	EGP	-	-	-	Major Facilitator
DIFHKINB_00141	6.03e-292	dpaL	4.3.1.15	-	E	ko:K01751	-	ko00000,ko01000	Pyridoxal-phosphate dependent enzyme
DIFHKINB_00142	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DIFHKINB_00143	2.85e-206	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DIFHKINB_00144	6.46e-137	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DIFHKINB_00145	5.92e-107	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DIFHKINB_00146	0.0	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
DIFHKINB_00147	1.85e-209	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
DIFHKINB_00148	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DIFHKINB_00149	6.56e-95	-	-	-	K	-	-	-	LytTr DNA-binding domain
DIFHKINB_00150	1.82e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
DIFHKINB_00151	5.34e-218	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
DIFHKINB_00152	8.85e-170	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	domain protein
DIFHKINB_00153	1.29e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DIFHKINB_00154	9.64e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
DIFHKINB_00155	3.54e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DIFHKINB_00156	2.75e-244	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DIFHKINB_00157	1.25e-119	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
DIFHKINB_00158	1.12e-268	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
DIFHKINB_00159	1.16e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DIFHKINB_00160	2.26e-142	yqeK	-	-	H	-	-	-	Hydrolase, HD family
DIFHKINB_00161	1.78e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DIFHKINB_00162	1.45e-279	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
DIFHKINB_00163	7.11e-124	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
DIFHKINB_00164	3.11e-169	csrR	-	-	K	-	-	-	response regulator
DIFHKINB_00165	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DIFHKINB_00166	2.72e-216	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DIFHKINB_00167	3.48e-58	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
DIFHKINB_00168	6.34e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DIFHKINB_00169	1.01e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
DIFHKINB_00170	9.43e-260	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DIFHKINB_00171	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DIFHKINB_00172	1.11e-261	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DIFHKINB_00173	5.34e-97	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DIFHKINB_00174	0.0	-	-	-	S	-	-	-	membrane
DIFHKINB_00175	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
DIFHKINB_00176	3.09e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
DIFHKINB_00177	1.17e-119	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DIFHKINB_00178	9.32e-154	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
DIFHKINB_00179	1.15e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
DIFHKINB_00180	1.47e-76	yqhL	-	-	P	-	-	-	Rhodanese-like protein
DIFHKINB_00181	1.18e-26	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
DIFHKINB_00182	3.2e-214	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DIFHKINB_00183	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
DIFHKINB_00184	1.34e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DIFHKINB_00185	6.93e-195	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
DIFHKINB_00187	5.22e-228	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
DIFHKINB_00188	7.15e-277	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
DIFHKINB_00189	9.64e-282	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
DIFHKINB_00190	2.41e-279	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
DIFHKINB_00191	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DIFHKINB_00192	1.1e-187	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
DIFHKINB_00193	6.36e-147	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
DIFHKINB_00194	4.08e-117	-	-	-	-	-	-	-	-
DIFHKINB_00195	8.42e-102	-	-	-	-	-	-	-	-
DIFHKINB_00196	4.69e-202	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
DIFHKINB_00197	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DIFHKINB_00198	2.17e-59	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
DIFHKINB_00199	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
DIFHKINB_00200	4.33e-36	-	-	-	-	-	-	-	-
DIFHKINB_00201	7.45e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
DIFHKINB_00202	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DIFHKINB_00203	1e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DIFHKINB_00204	2.82e-154	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
DIFHKINB_00205	4.94e-209	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
DIFHKINB_00206	2.2e-139	yjbH	-	-	Q	-	-	-	Thioredoxin
DIFHKINB_00207	7.51e-145	-	-	-	S	-	-	-	CYTH
DIFHKINB_00208	1.7e-146	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
DIFHKINB_00209	6.41e-194	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DIFHKINB_00210	2.38e-221	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DIFHKINB_00211	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
DIFHKINB_00212	5.46e-300	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
DIFHKINB_00213	6.1e-256	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
DIFHKINB_00214	1.88e-88	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
DIFHKINB_00215	4.6e-271	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
DIFHKINB_00216	1.88e-135	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DIFHKINB_00217	8.29e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
DIFHKINB_00218	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
DIFHKINB_00219	4.27e-293	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
DIFHKINB_00220	2.58e-296	ymfH	-	-	S	-	-	-	Peptidase M16
DIFHKINB_00221	8.62e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
DIFHKINB_00222	1.85e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
DIFHKINB_00223	8.9e-125	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DIFHKINB_00224	1.73e-249	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DIFHKINB_00225	1.38e-312	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
DIFHKINB_00226	2.33e-262	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
DIFHKINB_00227	1.39e-156	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
DIFHKINB_00228	2.75e-308	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
DIFHKINB_00229	1.29e-162	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
DIFHKINB_00230	2.35e-125	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DIFHKINB_00231	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DIFHKINB_00232	8.75e-236	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DIFHKINB_00233	3.75e-49	-	-	-	-	-	-	-	-
DIFHKINB_00234	6.07e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DIFHKINB_00235	6.19e-202	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DIFHKINB_00236	2.67e-239	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
DIFHKINB_00237	6.31e-223	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DIFHKINB_00238	5.12e-243	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
DIFHKINB_00239	2.39e-229	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
DIFHKINB_00240	1.77e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DIFHKINB_00241	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
DIFHKINB_00242	1.66e-247	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
DIFHKINB_00243	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
DIFHKINB_00244	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DIFHKINB_00245	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DIFHKINB_00246	1.44e-117	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
DIFHKINB_00247	3.19e-206	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
DIFHKINB_00248	1.88e-246	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
DIFHKINB_00249	8.24e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
DIFHKINB_00250	3.74e-130	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DIFHKINB_00251	0.0	ycaM	-	-	E	-	-	-	amino acid
DIFHKINB_00253	2.15e-237	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
DIFHKINB_00254	4.74e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DIFHKINB_00255	1.42e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
DIFHKINB_00256	8.39e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DIFHKINB_00257	1.18e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DIFHKINB_00258	1.07e-39	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
DIFHKINB_00259	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DIFHKINB_00260	5.95e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DIFHKINB_00261	1.38e-138	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
DIFHKINB_00263	1.8e-134	-	-	-	-	-	-	-	-
DIFHKINB_00264	1.41e-120	-	-	-	-	-	-	-	-
DIFHKINB_00265	3.3e-201	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DIFHKINB_00266	7.98e-172	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DIFHKINB_00267	1.82e-229	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
DIFHKINB_00268	2.49e-110	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
DIFHKINB_00269	3.17e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
DIFHKINB_00270	3.45e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
DIFHKINB_00271	1.25e-264	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
DIFHKINB_00272	1.04e-180	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DIFHKINB_00273	5.35e-176	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DIFHKINB_00274	1.71e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DIFHKINB_00275	1.29e-196	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DIFHKINB_00276	1.55e-224	ybbR	-	-	S	-	-	-	YbbR-like protein
DIFHKINB_00277	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DIFHKINB_00278	8.42e-191	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DIFHKINB_00279	2.49e-87	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DIFHKINB_00280	1.13e-81	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DIFHKINB_00281	2.94e-241	-	-	-	S	-	-	-	Putative adhesin
DIFHKINB_00282	5.95e-149	-	-	-	-	-	-	-	-
DIFHKINB_00283	1.07e-192	-	-	-	S	-	-	-	Alpha/beta hydrolase family
DIFHKINB_00284	2.74e-210	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
DIFHKINB_00285	1.95e-276	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DIFHKINB_00286	7.54e-125	-	-	-	S	-	-	-	VanZ like family
DIFHKINB_00287	2.13e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
DIFHKINB_00288	7.04e-230	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
DIFHKINB_00289	1.65e-226	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
DIFHKINB_00290	4.94e-54	comGC	-	-	U	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Required for transformation and DNA binding
DIFHKINB_00291	1.7e-87	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
DIFHKINB_00293	3.17e-113	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
DIFHKINB_00294	8.46e-239	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
DIFHKINB_00295	5.13e-287	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DIFHKINB_00297	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
DIFHKINB_00298	8.38e-36	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
DIFHKINB_00299	4.11e-105	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
DIFHKINB_00300	1.62e-100	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
DIFHKINB_00301	7.57e-245	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
DIFHKINB_00302	9.78e-89	-	-	-	S	-	-	-	SdpI/YhfL protein family
DIFHKINB_00303	3.82e-166	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
DIFHKINB_00304	0.0	yclK	-	-	T	-	-	-	Histidine kinase
DIFHKINB_00305	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DIFHKINB_00306	1.93e-139	vanZ	-	-	V	-	-	-	VanZ like family
DIFHKINB_00307	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
DIFHKINB_00308	2.98e-270	-	-	-	EGP	-	-	-	Major Facilitator
DIFHKINB_00309	2.98e-94	-	-	-	-	-	-	-	-
DIFHKINB_00312	2.07e-249	ampC	-	-	V	-	-	-	Beta-lactamase
DIFHKINB_00313	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
DIFHKINB_00314	5.77e-145	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
DIFHKINB_00315	1.27e-250	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DIFHKINB_00316	7.54e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DIFHKINB_00317	9.87e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DIFHKINB_00318	2.24e-147	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DIFHKINB_00319	1.43e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
DIFHKINB_00320	9.31e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DIFHKINB_00321	1.96e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DIFHKINB_00322	7.97e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DIFHKINB_00323	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DIFHKINB_00324	1.21e-219	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DIFHKINB_00325	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DIFHKINB_00326	2.1e-94	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
DIFHKINB_00327	3e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
DIFHKINB_00328	1.01e-228	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
DIFHKINB_00329	2.97e-21	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
DIFHKINB_00330	6.72e-70	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
DIFHKINB_00331	3.08e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
DIFHKINB_00332	3.34e-287	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
DIFHKINB_00333	3.9e-106	uspA	-	-	T	-	-	-	universal stress protein
DIFHKINB_00334	2.34e-08	-	-	-	-	-	-	-	-
DIFHKINB_00335	3.11e-307	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
DIFHKINB_00336	1.21e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
DIFHKINB_00337	7.54e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DIFHKINB_00339	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DIFHKINB_00340	1.5e-276	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
DIFHKINB_00341	1.54e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DIFHKINB_00342	7.16e-161	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
DIFHKINB_00343	4.76e-269	-	-	-	C	-	-	-	Glycerophosphoryl diester phosphodiesterase family
DIFHKINB_00344	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
DIFHKINB_00345	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DIFHKINB_00346	5.72e-301	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
DIFHKINB_00347	1.56e-160	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
DIFHKINB_00348	5.06e-144	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
DIFHKINB_00349	2.19e-225	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
DIFHKINB_00350	2.88e-189	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
DIFHKINB_00351	9.8e-124	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
DIFHKINB_00352	1.66e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
DIFHKINB_00353	7.67e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
DIFHKINB_00354	1.33e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
DIFHKINB_00355	7.69e-226	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DIFHKINB_00356	3.95e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
DIFHKINB_00357	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
DIFHKINB_00358	1.88e-222	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DIFHKINB_00359	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DIFHKINB_00360	2.01e-267	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DIFHKINB_00361	4.13e-197	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DIFHKINB_00362	2.81e-313	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DIFHKINB_00363	7.39e-309	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DIFHKINB_00364	4.43e-95	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DIFHKINB_00365	1.93e-47	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
DIFHKINB_00366	3.41e-188	ylmH	-	-	S	-	-	-	S4 domain protein
DIFHKINB_00367	2.05e-163	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
DIFHKINB_00368	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DIFHKINB_00369	3.24e-44	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
DIFHKINB_00370	6.31e-134	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
DIFHKINB_00372	1.68e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DIFHKINB_00373	7.12e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
DIFHKINB_00374	1.8e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
DIFHKINB_00375	3e-278	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DIFHKINB_00376	4.52e-161	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
DIFHKINB_00377	2.93e-150	-	-	-	S	-	-	-	repeat protein
DIFHKINB_00378	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DIFHKINB_00379	5.63e-226	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
DIFHKINB_00380	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DIFHKINB_00381	1.53e-47	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
DIFHKINB_00382	2.39e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DIFHKINB_00383	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
DIFHKINB_00384	1.66e-269	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
DIFHKINB_00385	7.67e-69	ylbG	-	-	S	-	-	-	UPF0298 protein
DIFHKINB_00386	7.11e-124	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
DIFHKINB_00387	5.77e-113	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DIFHKINB_00388	1.45e-236	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
DIFHKINB_00389	5.23e-132	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
DIFHKINB_00390	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
DIFHKINB_00391	1.23e-229	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
DIFHKINB_00392	1.97e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
DIFHKINB_00393	1.44e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DIFHKINB_00394	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DIFHKINB_00395	2e-206	-	-	-	-	-	-	-	-
DIFHKINB_00396	6.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DIFHKINB_00397	1.79e-278	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DIFHKINB_00398	2.5e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DIFHKINB_00399	5.34e-134	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
DIFHKINB_00400	3.98e-116	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DIFHKINB_00401	1.29e-107	-	-	-	-	-	-	-	-
DIFHKINB_00402	4.05e-102	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
DIFHKINB_00403	1.03e-300	-	-	-	-	-	-	-	-
DIFHKINB_00404	3.15e-158	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
DIFHKINB_00405	1.12e-212	-	-	-	-	-	-	-	-
DIFHKINB_00406	2.58e-103	-	-	-	K	-	-	-	DNA-templated transcription, initiation
DIFHKINB_00407	1.16e-217	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
DIFHKINB_00408	5.62e-193	epsB	-	-	M	-	-	-	biosynthesis protein
DIFHKINB_00409	3.18e-164	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
DIFHKINB_00410	5.69e-187	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
DIFHKINB_00411	2.06e-157	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
DIFHKINB_00412	1.21e-108	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
DIFHKINB_00413	2.18e-117	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
DIFHKINB_00414	3.49e-160	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
DIFHKINB_00415	5.28e-237	-	-	-	H	-	-	-	Glycosyl transferase family 11
DIFHKINB_00416	4.29e-207	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
DIFHKINB_00417	6.33e-254	-	-	-	M	-	-	-	Glycosyl transferases group 1
DIFHKINB_00418	2.05e-256	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
DIFHKINB_00419	7.35e-249	-	-	-	M	-	-	-	Glycosyl transferase family 2
DIFHKINB_00420	1.08e-270	-	-	-	-	-	-	-	-
DIFHKINB_00421	1.1e-281	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
DIFHKINB_00422	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
DIFHKINB_00423	4.11e-229	-	-	-	S	-	-	-	Acyltransferase family
DIFHKINB_00424	7.2e-235	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DIFHKINB_00425	2.28e-31	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DIFHKINB_00426	5.27e-235	-	-	-	V	-	-	-	Abi-like protein
DIFHKINB_00427	1.3e-286	-	-	-	KQ	-	-	-	helix_turn_helix, mercury resistance
DIFHKINB_00428	5e-268	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DIFHKINB_00429	1.66e-214	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DIFHKINB_00430	3.48e-152	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
DIFHKINB_00431	1.53e-243	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
DIFHKINB_00432	1.33e-09	licB2	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
DIFHKINB_00433	1.33e-99	-	-	-	S	-	-	-	HIRAN
DIFHKINB_00435	2.52e-210	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
DIFHKINB_00436	7.08e-21	-	-	-	-	-	-	-	-
DIFHKINB_00437	3.88e-284	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DIFHKINB_00438	1.14e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
DIFHKINB_00439	4.33e-185	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
DIFHKINB_00440	1.53e-139	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DIFHKINB_00441	1.71e-206	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DIFHKINB_00442	9.43e-201	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
DIFHKINB_00443	8.33e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
DIFHKINB_00444	3.98e-79	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
DIFHKINB_00445	1.67e-222	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
DIFHKINB_00446	4.52e-128	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DIFHKINB_00447	4.24e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DIFHKINB_00448	4.14e-177	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
DIFHKINB_00449	1.82e-228	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
DIFHKINB_00450	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
DIFHKINB_00451	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DIFHKINB_00452	2.29e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DIFHKINB_00453	9.1e-156	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
DIFHKINB_00454	1.15e-195	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DIFHKINB_00455	1.88e-313	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
DIFHKINB_00456	2.1e-78	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
DIFHKINB_00457	4.18e-160	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DIFHKINB_00458	6.56e-185	-	-	-	-	-	-	-	-
DIFHKINB_00459	1.55e-140	-	-	-	-	-	-	-	-
DIFHKINB_00460	1.45e-30	-	-	-	-	-	-	-	-
DIFHKINB_00461	1.27e-134	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
DIFHKINB_00462	2.2e-171	-	-	-	-	-	-	-	-
DIFHKINB_00463	8.88e-221	-	-	-	-	-	-	-	-
DIFHKINB_00464	7.14e-297	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
DIFHKINB_00465	7.47e-70	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
DIFHKINB_00466	2.48e-215	-	-	-	S	-	-	-	DUF218 domain
DIFHKINB_00467	4.51e-197	yxeH	-	-	S	-	-	-	hydrolase
DIFHKINB_00468	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
DIFHKINB_00469	1.11e-153	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DIFHKINB_00470	2.49e-166	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DIFHKINB_00471	2.34e-217	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DIFHKINB_00472	2.9e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DIFHKINB_00473	6.42e-237	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
DIFHKINB_00474	4.61e-310	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DIFHKINB_00475	2.26e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
DIFHKINB_00476	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
DIFHKINB_00477	5.88e-121	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DIFHKINB_00478	1.02e-136	pncA	-	-	Q	-	-	-	Isochorismatase family
DIFHKINB_00479	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DIFHKINB_00480	1.11e-163	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
DIFHKINB_00481	1.49e-163	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DIFHKINB_00482	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
DIFHKINB_00483	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
DIFHKINB_00484	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
DIFHKINB_00485	4.47e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DIFHKINB_00486	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
DIFHKINB_00487	1.75e-294	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
DIFHKINB_00488	9.14e-204	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DIFHKINB_00489	8.2e-214	-	-	-	K	-	-	-	LysR substrate binding domain
DIFHKINB_00490	0.0	-	-	-	C	-	-	-	FMN_bind
DIFHKINB_00491	1.57e-152	-	-	-	C	-	-	-	nitroreductase
DIFHKINB_00492	1.81e-38	-	-	-	-	-	-	-	-
DIFHKINB_00493	1.42e-66	-	-	-	-	-	-	-	-
DIFHKINB_00494	1.5e-56	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
DIFHKINB_00495	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
DIFHKINB_00496	1.15e-179	-	-	-	-	-	-	-	-
DIFHKINB_00497	2.05e-136	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
DIFHKINB_00499	8.4e-74	-	-	-	K	-	-	-	sequence-specific DNA binding
DIFHKINB_00500	2.21e-186	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
DIFHKINB_00501	1.1e-181	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
DIFHKINB_00502	5.46e-193	-	-	-	K	-	-	-	Helix-turn-helix domain
DIFHKINB_00503	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
DIFHKINB_00504	1.01e-110	yfhC	-	-	C	-	-	-	nitroreductase
DIFHKINB_00505	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
DIFHKINB_00506	2.39e-64	-	-	-	-	-	-	-	-
DIFHKINB_00507	1.36e-46	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DIFHKINB_00508	2.25e-31	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DIFHKINB_00509	7.8e-196	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
DIFHKINB_00510	9.1e-65	-	-	-	S	-	-	-	MazG-like family
DIFHKINB_00511	1.28e-82	-	-	-	-	-	-	-	-
DIFHKINB_00512	1.39e-174	-	-	-	-	-	-	-	-
DIFHKINB_00513	3.65e-54	-	-	-	-	-	-	-	-
DIFHKINB_00514	4.3e-185	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
DIFHKINB_00515	1.76e-193	-	-	-	S	-	-	-	Fic/DOC family
DIFHKINB_00516	6.11e-68	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	endonuclease activity
DIFHKINB_00517	2.21e-57	-	-	-	-	ko:K07473	-	ko00000,ko02048	-
DIFHKINB_00518	4.5e-129	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
DIFHKINB_00519	4.43e-115	-	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
DIFHKINB_00520	1.45e-173	-	-	-	F	-	-	-	Phosphorylase superfamily
DIFHKINB_00521	1.47e-109	-	-	-	S	-	-	-	ASCH
DIFHKINB_00522	5.83e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
DIFHKINB_00523	2e-207	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
DIFHKINB_00524	4.73e-203	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
DIFHKINB_00525	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
DIFHKINB_00526	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
DIFHKINB_00527	2.24e-238	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DIFHKINB_00528	2.53e-260	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
DIFHKINB_00529	1.67e-223	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
DIFHKINB_00530	1.8e-214	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
DIFHKINB_00531	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
DIFHKINB_00532	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
DIFHKINB_00533	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
DIFHKINB_00534	5.37e-117	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
DIFHKINB_00535	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
DIFHKINB_00536	2.06e-150	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
DIFHKINB_00537	6.69e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DIFHKINB_00538	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
DIFHKINB_00539	2.82e-153	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DIFHKINB_00540	2.28e-137	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
DIFHKINB_00541	1.37e-94	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DIFHKINB_00542	1.61e-275	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
DIFHKINB_00543	5.31e-306	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
DIFHKINB_00544	7.03e-224	degV1	-	-	S	-	-	-	DegV family
DIFHKINB_00545	2.74e-77	-	-	-	-	-	-	-	-
DIFHKINB_00546	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
DIFHKINB_00547	9.07e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DIFHKINB_00548	1.01e-220	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DIFHKINB_00549	4.62e-252	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
DIFHKINB_00550	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
DIFHKINB_00551	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
DIFHKINB_00552	5.72e-85	-	-	-	-	-	-	-	-
DIFHKINB_00553	7.93e-181	-	-	-	S	-	-	-	EDD domain protein, DegV family
DIFHKINB_00554	3.45e-197	-	-	-	-	-	-	-	-
DIFHKINB_00555	2.76e-214	lysR	-	-	K	-	-	-	Transcriptional regulator
DIFHKINB_00556	6.93e-261	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
DIFHKINB_00557	1.5e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
DIFHKINB_00558	6.77e-142	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DIFHKINB_00559	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
DIFHKINB_00560	3.5e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
DIFHKINB_00561	2.92e-231	-	-	-	K	-	-	-	Transcriptional regulator
DIFHKINB_00562	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DIFHKINB_00563	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DIFHKINB_00564	5.23e-151	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DIFHKINB_00565	1.4e-148	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
DIFHKINB_00566	2.95e-160	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
DIFHKINB_00567	6.25e-213	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
DIFHKINB_00568	6.98e-94	-	-	-	C	-	-	-	Aldo/keto reductase family
DIFHKINB_00569	3.31e-18	-	-	-	C	-	-	-	Aldo/keto reductase family
DIFHKINB_00570	7.15e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
DIFHKINB_00571	1.81e-134	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
DIFHKINB_00572	2.63e-43	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
DIFHKINB_00573	1.43e-312	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
DIFHKINB_00574	1.46e-161	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
DIFHKINB_00575	2.95e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DIFHKINB_00576	5.33e-90	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	methylated-DNA-[protein]-cysteine S-methyltransferase activity
DIFHKINB_00577	1.4e-99	-	-	-	K	-	-	-	Transcriptional regulator
DIFHKINB_00578	2.69e-63	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
DIFHKINB_00579	7e-114	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
DIFHKINB_00580	2.34e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
DIFHKINB_00581	1.24e-144	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
DIFHKINB_00582	1.13e-125	dpsB	-	-	P	-	-	-	Belongs to the Dps family
DIFHKINB_00583	9.51e-47	-	-	-	C	-	-	-	Heavy-metal-associated domain
DIFHKINB_00584	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
DIFHKINB_00585	2.06e-67	-	-	-	K	-	-	-	LytTr DNA-binding domain
DIFHKINB_00586	5.89e-90	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
DIFHKINB_00587	9.67e-222	yobV3	-	-	K	-	-	-	WYL domain
DIFHKINB_00588	0.000251	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
DIFHKINB_00589	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
DIFHKINB_00590	2.7e-43	-	-	-	G	ko:K03292	-	ko00000	Major facilitator Superfamily
DIFHKINB_00591	2.78e-80	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
DIFHKINB_00592	8.01e-276	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
DIFHKINB_00593	6.65e-152	-	-	-	GM	-	-	-	NAD(P)H-binding
DIFHKINB_00594	4.43e-296	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF1100)
DIFHKINB_00595	1.24e-129	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
DIFHKINB_00597	6.96e-201	-	-	-	C	-	-	-	Aldo keto reductase
DIFHKINB_00598	5.26e-157	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
DIFHKINB_00599	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
DIFHKINB_00600	2.4e-41	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DIFHKINB_00601	4.45e-42	-	3.2.1.31	-	G	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
DIFHKINB_00602	1.41e-242	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DIFHKINB_00603	3.13e-55	-	-	-	S	-	-	-	Cupin domain
DIFHKINB_00604	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
DIFHKINB_00605	0.0	-	-	-	P	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
DIFHKINB_00606	1.13e-98	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
DIFHKINB_00607	1.73e-294	dgoD	4.2.1.6, 4.2.1.8	-	M	ko:K01684,ko:K08323	ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Mandelate racemase muconate lactonizing enzyme
DIFHKINB_00608	2.79e-64	-	-	-	-	-	-	-	-
DIFHKINB_00609	5.79e-90	-	-	-	K	-	-	-	HxlR family
DIFHKINB_00610	9.19e-21	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
DIFHKINB_00611	1.55e-17	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DIFHKINB_00612	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
DIFHKINB_00613	7.35e-103	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
DIFHKINB_00614	2.64e-154	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
DIFHKINB_00615	5.55e-143	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
DIFHKINB_00616	0.0	-	-	-	-	-	-	-	-
DIFHKINB_00617	0.0	-	-	-	M	-	-	-	domain protein
DIFHKINB_00618	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
DIFHKINB_00620	0.0	-	-	-	S	-	-	-	domain, Protein
DIFHKINB_00621	1.21e-144	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
DIFHKINB_00622	1.27e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
DIFHKINB_00623	3.18e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
DIFHKINB_00624	6.43e-127	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
DIFHKINB_00625	2.18e-169	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
DIFHKINB_00626	3.29e-146	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DIFHKINB_00627	2.08e-179	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
DIFHKINB_00628	5.57e-55	-	-	-	K	ko:K15773	-	ko00000,ko02048,ko03000	peptidyl-tyrosine sulfation
DIFHKINB_00629	3.75e-57	-	-	-	-	-	-	-	-
DIFHKINB_00630	6.05e-69	-	-	-	-	-	-	-	-
DIFHKINB_00631	5.9e-94	-	-	-	K	-	-	-	Transcriptional regulator
DIFHKINB_00632	1.09e-230	-	-	-	S	-	-	-	Conserved hypothetical protein 698
DIFHKINB_00633	6.86e-92	-	-	-	-	-	-	-	-
DIFHKINB_00635	1.17e-129	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
DIFHKINB_00636	1.19e-134	-	-	-	K	-	-	-	LysR substrate binding domain
DIFHKINB_00637	3.03e-231	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
DIFHKINB_00638	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DIFHKINB_00639	3.16e-114	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DIFHKINB_00640	1.09e-221	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
DIFHKINB_00641	1.9e-316	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DIFHKINB_00642	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DIFHKINB_00643	1.3e-200	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
DIFHKINB_00644	7.68e-173	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DIFHKINB_00645	4.91e-204	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DIFHKINB_00646	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
DIFHKINB_00647	3.74e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
DIFHKINB_00648	2.31e-196	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
DIFHKINB_00649	1.38e-147	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
DIFHKINB_00650	1.66e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DIFHKINB_00651	8.13e-207	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DIFHKINB_00652	3.51e-142	-	-	-	-	-	-	-	-
DIFHKINB_00653	7.96e-135	-	-	-	-	-	-	-	-
DIFHKINB_00654	0.0	-	-	-	C	-	-	-	FMN_bind
DIFHKINB_00655	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
DIFHKINB_00656	0.0	-	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	EcoEI R protein C-terminal
DIFHKINB_00657	3.64e-270	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
DIFHKINB_00658	2.91e-229	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DIFHKINB_00659	2.45e-248	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
DIFHKINB_00660	0.0	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
DIFHKINB_00661	2.2e-195	-	-	-	-	-	-	-	-
DIFHKINB_00662	0.0	-	-	-	KL	-	-	-	domain protein
DIFHKINB_00663	1.27e-296	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
DIFHKINB_00664	7.91e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DIFHKINB_00665	1.6e-306	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
DIFHKINB_00666	5.27e-280	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
DIFHKINB_00667	1.03e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
DIFHKINB_00668	7.54e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DIFHKINB_00669	1.39e-94	-	-	-	M	-	-	-	Lysin motif
DIFHKINB_00670	8.87e-168	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
DIFHKINB_00671	3.57e-136	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DIFHKINB_00672	5.22e-174	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DIFHKINB_00673	1.95e-82	ribT	-	-	K	ko:K02859	-	ko00000	acetyltransferase
DIFHKINB_00674	1.17e-218	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
DIFHKINB_00675	1.65e-211	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
DIFHKINB_00676	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
DIFHKINB_00677	1.19e-231	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
DIFHKINB_00679	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
DIFHKINB_00680	1.57e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
DIFHKINB_00681	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
DIFHKINB_00682	5.51e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
DIFHKINB_00683	1.1e-62	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
DIFHKINB_00684	5.02e-185	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
DIFHKINB_00685	3.39e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DIFHKINB_00686	0.0	oatA	-	-	I	-	-	-	Acyltransferase
DIFHKINB_00687	1.79e-304	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DIFHKINB_00688	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DIFHKINB_00689	1.01e-222	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
DIFHKINB_00690	9.47e-137	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
DIFHKINB_00691	4.45e-150	-	-	-	GM	-	-	-	NmrA-like family
DIFHKINB_00692	4.62e-316	yagE	-	-	E	-	-	-	amino acid
DIFHKINB_00693	2.98e-140	-	-	-	S	-	-	-	Rib/alpha-like repeat
DIFHKINB_00694	4.27e-85	-	-	-	S	-	-	-	Domain of unknown function DUF1828
DIFHKINB_00695	2.11e-89	-	-	-	-	-	-	-	-
DIFHKINB_00696	3.4e-58	-	-	-	-	-	-	-	-
DIFHKINB_00697	1.22e-107	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
DIFHKINB_00698	3.8e-118	-	-	-	-	-	-	-	-
DIFHKINB_00699	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
DIFHKINB_00700	4.28e-312	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
DIFHKINB_00701	2.88e-96	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DIFHKINB_00702	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DIFHKINB_00703	2.32e-86	-	-	-	-	-	-	-	-
DIFHKINB_00704	4.27e-223	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
DIFHKINB_00705	1.7e-113	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DIFHKINB_00706	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
DIFHKINB_00707	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
DIFHKINB_00708	4.36e-242	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
DIFHKINB_00709	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
DIFHKINB_00710	1.54e-217	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
DIFHKINB_00711	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
DIFHKINB_00712	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
DIFHKINB_00713	2.57e-126	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DIFHKINB_00714	9.17e-242	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DIFHKINB_00715	5.71e-201	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
DIFHKINB_00716	5.81e-125	-	-	-	L	-	-	-	nuclease
DIFHKINB_00717	1.14e-195	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
DIFHKINB_00718	1.16e-63	-	-	-	K	-	-	-	Helix-turn-helix domain
DIFHKINB_00719	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
DIFHKINB_00720	9.84e-41	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
DIFHKINB_00721	6.08e-312	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DIFHKINB_00722	5.12e-132	-	-	-	I	-	-	-	PAP2 superfamily
DIFHKINB_00724	4.36e-204	lysR5	-	-	K	-	-	-	LysR substrate binding domain
DIFHKINB_00725	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
DIFHKINB_00726	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
DIFHKINB_00727	3.2e-126	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DIFHKINB_00728	1.21e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DIFHKINB_00729	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DIFHKINB_00730	0.0	potE	-	-	E	-	-	-	Amino Acid
DIFHKINB_00731	1.02e-124	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DIFHKINB_00732	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
DIFHKINB_00733	6.6e-159	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
DIFHKINB_00734	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DIFHKINB_00735	9.97e-252	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DIFHKINB_00736	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
DIFHKINB_00737	9.65e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DIFHKINB_00738	4.59e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DIFHKINB_00739	1.71e-155	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
DIFHKINB_00740	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
DIFHKINB_00741	4.29e-226	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
DIFHKINB_00742	2.1e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DIFHKINB_00743	6.74e-80	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DIFHKINB_00744	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DIFHKINB_00745	2.2e-62	-	-	-	J	-	-	-	ribosomal protein
DIFHKINB_00746	2.17e-62	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
DIFHKINB_00747	6.72e-277	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
DIFHKINB_00748	2.25e-107	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
DIFHKINB_00749	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DIFHKINB_00750	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DIFHKINB_00751	3.14e-293	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
DIFHKINB_00752	3.37e-178	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
DIFHKINB_00753	6.91e-175	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DIFHKINB_00754	2.87e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DIFHKINB_00755	7.13e-169	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
DIFHKINB_00756	4.15e-234	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DIFHKINB_00757	4.34e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
DIFHKINB_00758	1.87e-249	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
DIFHKINB_00759	3.62e-151	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
DIFHKINB_00760	1.31e-286	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
DIFHKINB_00761	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DIFHKINB_00762	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DIFHKINB_00763	3.41e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
DIFHKINB_00764	9.78e-46	ynzC	-	-	S	-	-	-	UPF0291 protein
DIFHKINB_00765	3.88e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DIFHKINB_00766	1.35e-149	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
DIFHKINB_00767	1.68e-98	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
DIFHKINB_00768	3.68e-151	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
DIFHKINB_00769	2.61e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DIFHKINB_00770	3.13e-175	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
DIFHKINB_00771	8.79e-125	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DIFHKINB_00772	1.37e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
DIFHKINB_00773	4.67e-290	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DIFHKINB_00774	2.45e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DIFHKINB_00775	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DIFHKINB_00776	1.78e-241	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DIFHKINB_00777	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
DIFHKINB_00778	5.24e-159	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DIFHKINB_00779	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
DIFHKINB_00780	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
DIFHKINB_00781	2.73e-209	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DIFHKINB_00782	3.16e-232	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DIFHKINB_00783	3.4e-228	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
DIFHKINB_00784	4.35e-244	oppD	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
DIFHKINB_00785	6.2e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DIFHKINB_00786	1.01e-234	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DIFHKINB_00787	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DIFHKINB_00788	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
DIFHKINB_00789	8.29e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
DIFHKINB_00790	9.04e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
DIFHKINB_00791	4.49e-158	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
DIFHKINB_00792	2.24e-155	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
DIFHKINB_00793	7.85e-210	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DIFHKINB_00794	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
DIFHKINB_00795	2.6e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
DIFHKINB_00796	1.55e-310	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DIFHKINB_00797	8.3e-225	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DIFHKINB_00798	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DIFHKINB_00799	1.63e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DIFHKINB_00800	5.97e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
DIFHKINB_00801	8.55e-64	-	-	-	-	-	-	-	-
DIFHKINB_00802	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
DIFHKINB_00803	1.85e-199	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
DIFHKINB_00804	1.46e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
DIFHKINB_00805	1.93e-46	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DIFHKINB_00806	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DIFHKINB_00807	2.23e-197	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DIFHKINB_00808	1.42e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DIFHKINB_00809	1.47e-95	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
DIFHKINB_00810	6.05e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DIFHKINB_00811	2.05e-254	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
DIFHKINB_00812	9.89e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
DIFHKINB_00813	6.82e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
DIFHKINB_00814	1.23e-84	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
DIFHKINB_00815	1.56e-191	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DIFHKINB_00816	1.5e-312	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
DIFHKINB_00817	4.08e-18	-	-	-	-	-	-	-	-
DIFHKINB_00818	4.18e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
DIFHKINB_00819	4.96e-121	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
DIFHKINB_00820	3.41e-193	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
DIFHKINB_00821	1.59e-77	-	-	-	-	-	-	-	-
DIFHKINB_00822	4.63e-74	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DIFHKINB_00823	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
DIFHKINB_00824	1.33e-263	-	-	-	P	-	-	-	Major Facilitator Superfamily
DIFHKINB_00825	8.33e-225	-	-	-	I	-	-	-	Carboxylesterase family
DIFHKINB_00826	1.12e-211	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
DIFHKINB_00827	7.29e-215	-	-	-	GK	-	-	-	ROK family
DIFHKINB_00828	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
DIFHKINB_00829	6.93e-81	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
DIFHKINB_00830	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
DIFHKINB_00831	4.6e-102	-	-	-	K	-	-	-	MerR HTH family regulatory protein
DIFHKINB_00832	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
DIFHKINB_00833	5.18e-128	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
DIFHKINB_00834	2.83e-165	pnb	-	-	C	-	-	-	nitroreductase
DIFHKINB_00835	3.01e-14	-	-	-	-	-	-	-	-
DIFHKINB_00836	3.38e-134	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
DIFHKINB_00842	2.1e-69	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
DIFHKINB_00843	1.37e-241	-	-	-	S	-	-	-	Phage minor structural protein
DIFHKINB_00844	4.06e-162	-	-	-	S	-	-	-	Phage tail protein
DIFHKINB_00845	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
DIFHKINB_00851	1.47e-52	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
DIFHKINB_00852	3.6e-251	-	-	-	S	-	-	-	peptidase activity
DIFHKINB_00853	1.47e-142	-	-	-	S	-	-	-	Clp protease
DIFHKINB_00854	2.22e-203	-	-	-	S	-	-	-	Phage portal protein
DIFHKINB_00856	1.86e-311	-	-	-	S	-	-	-	Phage Terminase
DIFHKINB_00857	2.31e-48	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
DIFHKINB_00858	3.76e-51	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
DIFHKINB_00859	2.09e-85	-	-	-	L	-	-	-	Phage terminase, small subunit
DIFHKINB_00860	1.11e-112	-	-	-	S	-	-	-	HNH endonuclease
DIFHKINB_00861	9.57e-102	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
DIFHKINB_00863	7.87e-57	-	-	-	S	-	-	-	VRR_NUC
DIFHKINB_00872	0.000386	-	-	-	K	-	-	-	Helix-turn-helix domain
DIFHKINB_00873	4.7e-312	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
DIFHKINB_00875	8.35e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
DIFHKINB_00877	6.28e-25	-	-	-	S	-	-	-	HNH endonuclease
DIFHKINB_00878	5.77e-91	-	-	-	S	-	-	-	AAA domain
DIFHKINB_00882	2.15e-18	-	-	-	-	-	-	-	-
DIFHKINB_00883	3.05e-44	-	-	-	-	-	-	-	-
DIFHKINB_00890	3.57e-21	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
DIFHKINB_00893	8.37e-42	-	-	-	-	-	-	-	-
DIFHKINB_00894	4.58e-134	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
DIFHKINB_00897	1.18e-25	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DIFHKINB_00898	1.15e-22	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DIFHKINB_00900	1.47e-59	-	-	-	T	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
DIFHKINB_00902	3.51e-14	-	-	-	-	-	-	-	-
DIFHKINB_00904	4.64e-276	-	-	-	S	-	-	-	Phage integrase family
DIFHKINB_00905	2.52e-289	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
DIFHKINB_00906	6.22e-140	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
DIFHKINB_00907	2.46e-95	-	-	-	-	-	-	-	-
DIFHKINB_00908	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DIFHKINB_00910	1.13e-158	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DIFHKINB_00911	1.1e-184	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
DIFHKINB_00912	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
DIFHKINB_00913	8.93e-90	-	-	-	-	-	-	-	-
DIFHKINB_00914	2.75e-74	-	-	-	-	-	-	-	-
DIFHKINB_00915	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
DIFHKINB_00916	3.86e-300	sptS	-	-	T	-	-	-	Histidine kinase
DIFHKINB_00917	1.44e-149	dltr	-	-	K	-	-	-	response regulator
DIFHKINB_00918	2.97e-149	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
DIFHKINB_00919	1.52e-28	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
DIFHKINB_00920	4.54e-91	-	-	-	O	-	-	-	OsmC-like protein
DIFHKINB_00921	0.0	-	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
DIFHKINB_00922	1.02e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
DIFHKINB_00923	3.18e-199	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
DIFHKINB_00924	1.94e-217	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
DIFHKINB_00925	6.47e-214	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
DIFHKINB_00926	2.09e-207	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
DIFHKINB_00927	4.75e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
DIFHKINB_00928	3.66e-112	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
DIFHKINB_00929	1.15e-277	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
DIFHKINB_00931	1.45e-232	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
DIFHKINB_00932	7.8e-75	-	-	-	S	-	-	-	Pfam:Phage_holin_6_1
DIFHKINB_00933	1.85e-58	-	-	-	-	-	-	-	-
DIFHKINB_00934	1.42e-84	-	-	-	-	-	-	-	-
DIFHKINB_00936	8.81e-114	-	-	-	-	-	-	-	-
DIFHKINB_00937	0.0	-	-	-	-	-	-	-	-
DIFHKINB_00938	7.06e-126	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2313)
DIFHKINB_00939	8.96e-273	-	-	-	S	-	-	-	Baseplate J-like protein
DIFHKINB_00940	5.12e-81	-	-	-	S	-	-	-	Protein of unknown function (DUF2634)
DIFHKINB_00941	3.12e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF2577)
DIFHKINB_00942	1.55e-253	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
DIFHKINB_00943	3.63e-153	xkdP	-	-	S	-	-	-	protein containing LysM domain
DIFHKINB_00944	0.0	-	-	-	S	-	-	-	phage tail tape measure protein
DIFHKINB_00945	9.06e-88	-	-	-	S	-	-	-	Pfam:Phage_TAC_5
DIFHKINB_00946	2.92e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF2001)
DIFHKINB_00947	0.0	-	-	-	S	-	-	-	Phage tail sheath protein
DIFHKINB_00948	3.86e-42	-	-	-	-	-	-	-	-
DIFHKINB_00949	5.98e-91	-	-	-	-	-	-	-	-
DIFHKINB_00950	1.81e-103	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
DIFHKINB_00951	6.81e-83	-	-	-	-	-	-	-	-
DIFHKINB_00952	7.13e-87	-	-	-	-	-	-	-	-
DIFHKINB_00953	8.29e-247	-	-	-	-	-	-	-	-
DIFHKINB_00954	1.48e-117	-	-	-	S	-	-	-	viral scaffold
DIFHKINB_00955	6.92e-282	-	-	-	S	-	-	-	Phage Mu protein F like protein
DIFHKINB_00956	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
DIFHKINB_00957	1.01e-314	-	-	-	S	-	-	-	DNA packaging
DIFHKINB_00958	3.95e-115	-	-	-	S	-	-	-	Terminase small subunit
DIFHKINB_00959	3.04e-154	-	-	-	-	-	-	-	-
DIFHKINB_00961	4.56e-154	-	-	-	C	-	-	-	Domain of unknown function (DUF4145)
DIFHKINB_00963	4.13e-65	-	-	-	K	-	-	-	chromosome segregation
DIFHKINB_00965	1.83e-123	-	-	-	-	-	-	-	-
DIFHKINB_00966	2.6e-35	-	-	-	-	-	-	-	-
DIFHKINB_00967	2.62e-40	-	-	-	-	-	-	-	-
DIFHKINB_00968	1.97e-48	-	-	-	-	-	-	-	-
DIFHKINB_00969	2.42e-30	-	-	-	-	-	-	-	-
DIFHKINB_00970	1.24e-103	-	-	-	L	-	-	-	Endodeoxyribonuclease RusA
DIFHKINB_00971	7.41e-86	-	-	-	-	-	-	-	-
DIFHKINB_00974	1.29e-57	-	-	-	-	-	-	-	-
DIFHKINB_00977	4.7e-177	-	-	-	K	ko:K07741	-	ko00000	Phage antirepressor protein KilAC domain
DIFHKINB_00979	4.85e-68	-	-	-	S	-	-	-	sequence-specific DNA binding
DIFHKINB_00980	1.51e-165	-	-	-	S	-	-	-	Conserved phage C-terminus (Phg_2220_C)
DIFHKINB_00981	7.78e-53	-	-	-	S	-	-	-	ERF superfamily
DIFHKINB_00983	1.05e-51	-	-	-	-	-	-	-	-
DIFHKINB_00984	2.88e-21	-	-	-	-	-	-	-	-
DIFHKINB_00986	6.29e-77	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
DIFHKINB_00987	1.01e-07	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DIFHKINB_00988	1.45e-74	-	-	-	K	-	-	-	Helix-turn-helix domain
DIFHKINB_00989	5.97e-114	-	-	-	S	-	-	-	Pfam:Peptidase_M78
DIFHKINB_00990	1.63e-139	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
DIFHKINB_00992	1.96e-275	-	-	-	S	-	-	-	Phage integrase family
DIFHKINB_00994	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DIFHKINB_00995	1.11e-277	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
DIFHKINB_00996	3.55e-176	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
DIFHKINB_00997	2.29e-299	-	-	-	E	ko:K03294	-	ko00000	amino acid
DIFHKINB_00998	1.73e-132	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
DIFHKINB_00999	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
DIFHKINB_01000	8.05e-171	-	-	-	-	-	-	-	-
DIFHKINB_01001	1.24e-153	-	-	-	C	-	-	-	nitroreductase
DIFHKINB_01002	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
DIFHKINB_01003	3.92e-178	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
DIFHKINB_01004	7.47e-70	-	-	-	S	-	-	-	Enterocin A Immunity
DIFHKINB_01005	2.4e-172	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
DIFHKINB_01006	5.75e-224	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
DIFHKINB_01007	8.05e-166	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DIFHKINB_01008	1.58e-212	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DIFHKINB_01010	1.15e-109	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
DIFHKINB_01011	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
DIFHKINB_01012	4.1e-152	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
DIFHKINB_01013	2.13e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DIFHKINB_01014	3.84e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DIFHKINB_01015	2.05e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
DIFHKINB_01016	1.24e-216	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
DIFHKINB_01017	2.89e-206	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
DIFHKINB_01018	2.8e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DIFHKINB_01019	2.68e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DIFHKINB_01020	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
DIFHKINB_01021	3.34e-208	-	-	-	S	-	-	-	Phospholipase, patatin family
DIFHKINB_01022	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
DIFHKINB_01023	7.42e-75	-	-	-	S	-	-	-	Enterocin A Immunity
DIFHKINB_01025	9.4e-100	-	-	-	EGP	-	-	-	Major facilitator superfamily
DIFHKINB_01026	9.09e-204	-	-	-	EGP	-	-	-	Major facilitator superfamily
DIFHKINB_01027	9.28e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
DIFHKINB_01028	1.16e-128	-	-	-	S	-	-	-	Putative adhesin
DIFHKINB_01029	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DIFHKINB_01030	3.51e-167	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
DIFHKINB_01031	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
DIFHKINB_01032	1.77e-199	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
DIFHKINB_01033	7.95e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DIFHKINB_01034	1.5e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DIFHKINB_01035	1.18e-191	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DIFHKINB_01036	4.37e-176	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DIFHKINB_01037	6.61e-190	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DIFHKINB_01038	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
DIFHKINB_01039	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
DIFHKINB_01040	2.27e-98	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
DIFHKINB_01041	2.6e-202	-	-	-	S	-	-	-	Alpha beta hydrolase
DIFHKINB_01042	2.81e-265	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
DIFHKINB_01043	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
DIFHKINB_01044	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Glycosyl hydrolases family 31
DIFHKINB_01045	5.45e-232	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
DIFHKINB_01046	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
DIFHKINB_01047	2.38e-94	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
DIFHKINB_01048	1.49e-194	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
DIFHKINB_01049	1.4e-155	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
DIFHKINB_01050	5.16e-115	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
DIFHKINB_01052	5.75e-267	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
DIFHKINB_01053	1.64e-108	-	-	-	-	-	-	-	-
DIFHKINB_01054	4.11e-95	rmaE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
DIFHKINB_01055	7.95e-45	-	-	-	-	-	-	-	-
DIFHKINB_01056	3.36e-254	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
DIFHKINB_01057	1.23e-144	-	-	-	I	-	-	-	Acid phosphatase homologues
DIFHKINB_01058	1.08e-216	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
DIFHKINB_01059	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
DIFHKINB_01060	0.0	-	-	-	C	-	-	-	FMN_bind
DIFHKINB_01061	1.31e-211	-	-	-	K	-	-	-	LysR family
DIFHKINB_01062	3.04e-258	-	-	-	S	-	-	-	PFAM Archaeal ATPase
DIFHKINB_01063	0.0	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DIFHKINB_01064	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
DIFHKINB_01065	6.12e-76	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
DIFHKINB_01066	4.16e-196	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	CAT RNA binding domain
DIFHKINB_01067	3.59e-52	-	-	-	-	-	-	-	-
DIFHKINB_01068	0.0	gatC	-	-	G	ko:K20114	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
DIFHKINB_01069	6.32e-68	-	2.7.1.204	-	G	ko:K20113	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DIFHKINB_01070	1.71e-111	-	2.7.1.204	-	G	ko:K20112	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DIFHKINB_01071	5.07e-166	-	-	-	S	-	-	-	Domain of unknown function (DUF4867)
DIFHKINB_01072	2.86e-137	-	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
DIFHKINB_01073	9.37e-96	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
DIFHKINB_01074	2.29e-176	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
DIFHKINB_01075	2.57e-307	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
DIFHKINB_01076	7.08e-169	-	-	-	K	-	-	-	Transcriptional regulator
DIFHKINB_01077	1.99e-193	-	-	-	S	-	-	-	hydrolase
DIFHKINB_01078	4.86e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF1440)
DIFHKINB_01079	1.83e-186	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
DIFHKINB_01080	4.48e-102	-	-	-	K	-	-	-	acetyltransferase
DIFHKINB_01081	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
DIFHKINB_01082	2.64e-92	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DIFHKINB_01083	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
DIFHKINB_01084	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
DIFHKINB_01085	6.63e-188	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
DIFHKINB_01086	4.43e-177	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease
DIFHKINB_01087	9.08e-210	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
DIFHKINB_01088	4.71e-139	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
DIFHKINB_01089	8.55e-247	-	-	-	S	-	-	-	Bacteriocin helveticin-J
DIFHKINB_01090	2.16e-108	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
DIFHKINB_01091	9.45e-145	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
DIFHKINB_01092	3.72e-166	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
DIFHKINB_01093	3.04e-123	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
DIFHKINB_01095	3.38e-76	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
DIFHKINB_01096	4.65e-100	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
DIFHKINB_01097	4.75e-67	-	-	-	-	-	-	-	-
DIFHKINB_01098	3.12e-220	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
DIFHKINB_01099	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
DIFHKINB_01100	5.83e-222	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
DIFHKINB_01101	1.96e-161	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
DIFHKINB_01102	1.32e-192	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DIFHKINB_01103	2.27e-164	-	-	-	-	-	-	-	-
DIFHKINB_01104	1.82e-278	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
DIFHKINB_01105	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
DIFHKINB_01106	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
DIFHKINB_01107	1.7e-164	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
DIFHKINB_01108	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
DIFHKINB_01109	3.1e-276	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DIFHKINB_01117	4.1e-09	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
DIFHKINB_01118	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DIFHKINB_01119	3.69e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DIFHKINB_01120	2.75e-167	-	-	-	S	-	-	-	membrane
DIFHKINB_01121	6.13e-38	-	-	-	K	-	-	-	LytTr DNA-binding domain
DIFHKINB_01122	1.55e-133	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
DIFHKINB_01123	1.45e-150	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DIFHKINB_01124	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
DIFHKINB_01125	1.51e-100	-	-	-	-	-	-	-	-
DIFHKINB_01126	6.18e-199	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DIFHKINB_01127	0.0	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 32
DIFHKINB_01128	0.0	scrA5	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DIFHKINB_01129	0.0	bglC1	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
DIFHKINB_01130	2.19e-196	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
DIFHKINB_01131	3.25e-298	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
DIFHKINB_01132	1.01e-71	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
DIFHKINB_01133	2.75e-64	-	-	-	L	ko:K07473	-	ko00000,ko02048	bacterial-type proximal promoter sequence-specific DNA binding
DIFHKINB_01134	1.53e-102	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
DIFHKINB_01135	3.38e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DIFHKINB_01136	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DIFHKINB_01137	8.5e-242	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DIFHKINB_01138	1.2e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
DIFHKINB_01139	1.49e-64	-	-	-	-	-	-	-	-
DIFHKINB_01140	4.64e-306	eriC	-	-	P	ko:K03281	-	ko00000	chloride
DIFHKINB_01141	3.45e-150	-	-	-	-	-	-	-	-
DIFHKINB_01142	6.29e-89	-	-	-	-	-	-	-	-
DIFHKINB_01143	1.35e-116	-	-	-	-	-	-	-	-
DIFHKINB_01144	1.13e-16	-	-	-	D	-	-	-	nuclear chromosome segregation
DIFHKINB_01145	8.61e-251	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DIFHKINB_01146	3.43e-127	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
DIFHKINB_01147	3.02e-170	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
DIFHKINB_01148	8.12e-113	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
DIFHKINB_01149	2.57e-168	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
DIFHKINB_01150	8.76e-201	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DIFHKINB_01151	3.89e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
DIFHKINB_01152	1.39e-197	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
DIFHKINB_01153	8.23e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
DIFHKINB_01154	7.09e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DIFHKINB_01155	3.68e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
DIFHKINB_01156	1.53e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DIFHKINB_01157	9.41e-69	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DIFHKINB_01158	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DIFHKINB_01159	2.52e-106	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DIFHKINB_01160	6.96e-33	-	-	-	-	-	-	-	-
DIFHKINB_01161	3.19e-145	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
DIFHKINB_01162	3.25e-44	-	-	-	-	-	-	-	-
DIFHKINB_01163	4.14e-198	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion transport protein
DIFHKINB_01164	3.25e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DIFHKINB_01165	2.35e-126	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DIFHKINB_01166	5.9e-188	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
DIFHKINB_01167	1.29e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
DIFHKINB_01168	5.35e-140	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
DIFHKINB_01169	6.1e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DIFHKINB_01170	2.69e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DIFHKINB_01171	2.58e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
DIFHKINB_01172	9.78e-18	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DIFHKINB_01173	1.48e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
DIFHKINB_01174	6.02e-246	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
DIFHKINB_01175	8.29e-292	-	-	-	G	-	-	-	Major Facilitator Superfamily
DIFHKINB_01176	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DIFHKINB_01177	9.47e-266	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
DIFHKINB_01178	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
DIFHKINB_01179	1.19e-45	-	-	-	-	-	-	-	-
DIFHKINB_01180	3.38e-128	-	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factor activity
DIFHKINB_01181	0.0	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DIFHKINB_01182	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
DIFHKINB_01183	5.42e-75	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
DIFHKINB_01184	9.1e-199	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	PRD domain
DIFHKINB_01185	1.62e-179	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DIFHKINB_01186	2.73e-102	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DIFHKINB_01187	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
DIFHKINB_01188	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DIFHKINB_01189	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DIFHKINB_01190	3.67e-131	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
DIFHKINB_01191	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
DIFHKINB_01192	1.2e-236	-	-	-	S	-	-	-	AAA domain
DIFHKINB_01193	5.21e-164	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DIFHKINB_01194	1.33e-35	-	-	-	-	-	-	-	-
DIFHKINB_01195	2.66e-56	-	-	-	-	-	-	-	-
DIFHKINB_01196	5.88e-199	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
DIFHKINB_01197	5.56e-70	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
DIFHKINB_01198	1.83e-165	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
DIFHKINB_01199	1.27e-141	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
DIFHKINB_01200	5.1e-206	-	-	-	GM	-	-	-	NmrA-like family
DIFHKINB_01201	1.8e-104	-	-	-	-	-	-	-	-
DIFHKINB_01202	4.61e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
DIFHKINB_01203	7.82e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DIFHKINB_01204	8.78e-195	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DIFHKINB_01205	2.19e-180	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DIFHKINB_01206	1.86e-208	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DIFHKINB_01207	1.1e-200	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DIFHKINB_01208	3.85e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
DIFHKINB_01209	2.19e-219	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DIFHKINB_01210	4.46e-81	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DIFHKINB_01211	1.92e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DIFHKINB_01212	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
DIFHKINB_01213	4.46e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DIFHKINB_01214	4.87e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DIFHKINB_01215	2.42e-299	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DIFHKINB_01216	8.21e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
DIFHKINB_01217	3.44e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
DIFHKINB_01218	9.33e-107	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DIFHKINB_01219	1.09e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DIFHKINB_01220	6.14e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DIFHKINB_01221	1.32e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DIFHKINB_01222	1.73e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DIFHKINB_01223	4.3e-124	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DIFHKINB_01224	1.67e-46	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DIFHKINB_01225	6.02e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DIFHKINB_01226	7.74e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DIFHKINB_01227	2.92e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
DIFHKINB_01228	4.26e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DIFHKINB_01229	7.46e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DIFHKINB_01230	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DIFHKINB_01231	6.08e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DIFHKINB_01232	4.88e-199	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DIFHKINB_01233	7.29e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DIFHKINB_01234	3.16e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
DIFHKINB_01235	5.06e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DIFHKINB_01236	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
DIFHKINB_01237	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DIFHKINB_01238	1.14e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DIFHKINB_01239	3.6e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DIFHKINB_01240	1.28e-154	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
DIFHKINB_01241	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DIFHKINB_01242	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DIFHKINB_01243	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DIFHKINB_01246	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
DIFHKINB_01247	1.36e-245	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DIFHKINB_01248	1.66e-207	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DIFHKINB_01249	0.0	-	-	-	S	-	-	-	membrane
DIFHKINB_01250	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DIFHKINB_01251	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DIFHKINB_01252	3.27e-80	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
DIFHKINB_01253	5.29e-78	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
DIFHKINB_01254	8.68e-47	yabO	-	-	J	-	-	-	S4 domain protein
DIFHKINB_01255	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DIFHKINB_01256	2.68e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DIFHKINB_01257	2.31e-231	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
DIFHKINB_01258	5.46e-161	-	-	-	S	-	-	-	(CBS) domain
DIFHKINB_01259	1.69e-278	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DIFHKINB_01260	3.03e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DIFHKINB_01261	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
DIFHKINB_01262	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DIFHKINB_01263	1.28e-54	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
DIFHKINB_01264	0.0	-	-	-	E	-	-	-	amino acid
DIFHKINB_01265	1.27e-173	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DIFHKINB_01266	1.2e-182	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
DIFHKINB_01267	5.27e-241	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
DIFHKINB_01268	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
DIFHKINB_01269	2.21e-294	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DIFHKINB_01270	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DIFHKINB_01272	4.92e-104	-	-	-	-	-	-	-	-
DIFHKINB_01273	1.67e-101	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
DIFHKINB_01274	4.68e-238	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DIFHKINB_01275	4.86e-28	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DIFHKINB_01276	1.64e-52	-	-	-	-	-	-	-	-
DIFHKINB_01277	9.92e-266	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
DIFHKINB_01278	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
DIFHKINB_01279	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
DIFHKINB_01280	1.97e-123	-	-	-	-	-	-	-	-
DIFHKINB_01281	2.08e-127	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DIFHKINB_01282	2.15e-85	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
DIFHKINB_01283	5.66e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
DIFHKINB_01284	9.45e-67	-	-	-	-	-	-	-	-
DIFHKINB_01286	7.78e-63	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
DIFHKINB_01287	6.29e-146	-	-	-	S	-	-	-	Flavodoxin-like fold
DIFHKINB_01288	1.63e-121	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DIFHKINB_01289	9.94e-90	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
DIFHKINB_01290	7.98e-50	-	-	-	-	-	-	-	-
DIFHKINB_01291	1.05e-228	-	-	-	K	-	-	-	Helix-turn-helix
DIFHKINB_01293	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
DIFHKINB_01294	1.59e-172	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
DIFHKINB_01295	1.66e-136	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DIFHKINB_01296	4.58e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
DIFHKINB_01297	6.24e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DIFHKINB_01298	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DIFHKINB_01299	3.78e-92	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
DIFHKINB_01300	4.73e-96	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
DIFHKINB_01301	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
DIFHKINB_01302	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
DIFHKINB_01303	2.93e-199	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DIFHKINB_01304	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DIFHKINB_01305	1.58e-293	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
DIFHKINB_01306	1.12e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
DIFHKINB_01307	2.69e-149	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
DIFHKINB_01308	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
DIFHKINB_01309	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
DIFHKINB_01310	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
DIFHKINB_01311	1.05e-227	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
DIFHKINB_01312	9.21e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DIFHKINB_01313	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DIFHKINB_01314	7.77e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
DIFHKINB_01315	2.99e-49	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
DIFHKINB_01316	3.56e-206	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DIFHKINB_01317	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DIFHKINB_01318	2.07e-189	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
DIFHKINB_01319	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DIFHKINB_01320	5.06e-115	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
DIFHKINB_01321	1.52e-129	-	-	-	S	ko:K06872	-	ko00000	TPM domain
DIFHKINB_01322	6.82e-119	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
DIFHKINB_01323	4.06e-247	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
DIFHKINB_01324	2.85e-147	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
DIFHKINB_01326	2.21e-148	-	-	-	-	-	-	-	-
DIFHKINB_01327	3.8e-202	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
DIFHKINB_01328	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DIFHKINB_01329	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DIFHKINB_01330	2.42e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DIFHKINB_01331	1.76e-68	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
DIFHKINB_01332	1.1e-172	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
DIFHKINB_01333	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DIFHKINB_01334	2.83e-57	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
DIFHKINB_01335	8.05e-166	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
DIFHKINB_01336	1.29e-315	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DIFHKINB_01337	2.08e-105	-	-	-	-	-	-	-	-
DIFHKINB_01338	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DIFHKINB_01339	1.47e-100	-	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
DIFHKINB_01340	4.87e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DIFHKINB_01341	8.46e-81	-	-	-	-	-	-	-	-
DIFHKINB_01342	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
DIFHKINB_01343	2.24e-160	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
DIFHKINB_01344	0.0	pepC1	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
DIFHKINB_01346	9.21e-309	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DIFHKINB_01347	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
DIFHKINB_01348	1.13e-145	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DIFHKINB_01349	3.28e-260	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
DIFHKINB_01350	4.25e-219	-	-	-	G	-	-	-	Aldose 1-epimerase
DIFHKINB_01351	2.21e-195	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
DIFHKINB_01352	7.1e-152	-	-	-	-	-	-	-	-
DIFHKINB_01353	1.56e-227	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
DIFHKINB_01354	5.36e-92	-	-	-	S	-	-	-	GtrA-like protein
DIFHKINB_01355	4.38e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DIFHKINB_01356	1.11e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DIFHKINB_01357	2.22e-97	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
DIFHKINB_01358	3.41e-193	-	-	-	-	-	-	-	-
DIFHKINB_01359	2.11e-175	-	-	-	-	-	-	-	-
DIFHKINB_01360	6.12e-230	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
DIFHKINB_01361	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
DIFHKINB_01362	2.55e-185	-	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
DIFHKINB_01363	0.0	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
DIFHKINB_01364	0.0	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DIFHKINB_01365	3.38e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
DIFHKINB_01366	1.75e-39	-	-	-	-	-	-	-	-
DIFHKINB_01367	1.47e-162	-	-	-	-	-	-	-	-
DIFHKINB_01368	1.06e-95	-	-	-	-	-	-	-	-
DIFHKINB_01369	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
DIFHKINB_01370	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
DIFHKINB_01371	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
DIFHKINB_01372	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
DIFHKINB_01373	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
DIFHKINB_01374	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DIFHKINB_01375	6.42e-210	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
DIFHKINB_01376	9.83e-175	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
DIFHKINB_01377	5.5e-302	-	-	-	D	-	-	-	transport
DIFHKINB_01378	9.39e-238	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
DIFHKINB_01379	2.19e-290	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
DIFHKINB_01380	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
DIFHKINB_01381	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
DIFHKINB_01382	3.64e-291	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
DIFHKINB_01383	1.83e-134	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
DIFHKINB_01384	8.75e-177	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DIFHKINB_01385	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
DIFHKINB_01386	2.3e-83	-	-	-	-	-	-	-	-
DIFHKINB_01387	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
DIFHKINB_01388	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
DIFHKINB_01389	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
DIFHKINB_01390	6.97e-107	-	-	-	-	-	-	-	-
DIFHKINB_01391	8.69e-189	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DIFHKINB_01392	2.46e-169	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DIFHKINB_01393	2.58e-181	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DIFHKINB_01394	9.38e-47	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
DIFHKINB_01395	2.35e-121	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
DIFHKINB_01397	4.96e-113	usp5	-	-	T	-	-	-	universal stress protein
DIFHKINB_01398	3.05e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
DIFHKINB_01399	4.26e-171	-	-	-	K	-	-	-	UTRA domain
DIFHKINB_01400	1.89e-129	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DIFHKINB_01401	3.82e-114	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
DIFHKINB_01402	2.07e-242	-	-	-	-	-	-	-	-
DIFHKINB_01403	8.35e-277	-	-	-	S	-	-	-	zinc-ribbon domain
DIFHKINB_01404	3.49e-23	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
DIFHKINB_01405	1.6e-89	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
DIFHKINB_01406	2.13e-190	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
DIFHKINB_01407	1.87e-196	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
DIFHKINB_01408	5.59e-109	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
DIFHKINB_01409	2.64e-291	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DIFHKINB_01410	5.87e-276	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
DIFHKINB_01411	8.33e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
DIFHKINB_01412	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
DIFHKINB_01413	6.44e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DIFHKINB_01414	1.61e-155	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
DIFHKINB_01415	1.02e-239	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
DIFHKINB_01416	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
DIFHKINB_01417	1.03e-151	-	-	-	-	-	-	-	-
DIFHKINB_01418	6.59e-265	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
DIFHKINB_01419	0.0	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
DIFHKINB_01420	8.47e-180	-	-	-	-	-	-	-	-
DIFHKINB_01421	2.91e-148	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DIFHKINB_01422	4.1e-307	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
DIFHKINB_01423	8.76e-283	-	-	-	S	-	-	-	CAAX protease self-immunity
DIFHKINB_01424	7.71e-231	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DIFHKINB_01425	9.68e-83	-	-	-	-	-	-	-	-
DIFHKINB_01426	5.7e-160	-	-	-	S	-	-	-	Alpha/beta hydrolase family
DIFHKINB_01427	3.33e-205	-	-	-	M	-	-	-	Glycosyltransferase like family 2
DIFHKINB_01428	4.75e-219	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
DIFHKINB_01429	3.86e-187	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DIFHKINB_01430	2.39e-225	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DIFHKINB_01431	1.81e-159	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
DIFHKINB_01432	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DIFHKINB_01433	1.33e-104	-	-	-	-	-	-	-	-
DIFHKINB_01434	1.63e-172	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
DIFHKINB_01435	5.26e-123	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
DIFHKINB_01436	2.16e-168	terC	-	-	P	-	-	-	Integral membrane protein TerC family
DIFHKINB_01437	5.23e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
DIFHKINB_01438	3.97e-136	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
DIFHKINB_01439	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DIFHKINB_01440	7.38e-177	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DIFHKINB_01441	2.73e-208	-	-	-	L	-	-	-	HNH nucleases
DIFHKINB_01442	1.11e-154	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
DIFHKINB_01443	1.09e-272	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
DIFHKINB_01444	8.23e-308	-	-	-	M	-	-	-	Glycosyl transferase
DIFHKINB_01446	1.57e-199	-	-	-	-	-	-	-	-
DIFHKINB_01447	1.14e-23	-	-	-	-	-	-	-	-
DIFHKINB_01448	6.45e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
DIFHKINB_01449	4.66e-240	ysdE	-	-	P	-	-	-	Citrate transporter
DIFHKINB_01450	7.65e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
DIFHKINB_01451	5.77e-191	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
DIFHKINB_01452	3.49e-219	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
DIFHKINB_01453	3.01e-124	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
DIFHKINB_01454	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DIFHKINB_01455	2.2e-142	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
DIFHKINB_01456	3.66e-108	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DIFHKINB_01457	1.48e-263	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
DIFHKINB_01458	6.41e-193	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
DIFHKINB_01459	2.3e-190	yycI	-	-	S	-	-	-	YycH protein
DIFHKINB_01460	0.0	yycH	-	-	S	-	-	-	YycH protein
DIFHKINB_01461	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DIFHKINB_01462	3.03e-167	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
DIFHKINB_01465	1.3e-194	-	-	-	I	-	-	-	Acyl-transferase
DIFHKINB_01466	9.16e-202	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
DIFHKINB_01467	3.05e-235	-	-	-	M	-	-	-	Glycosyl transferase family 8
DIFHKINB_01468	2.51e-236	-	-	-	M	-	-	-	Glycosyl transferase family 8
DIFHKINB_01469	1.42e-211	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
DIFHKINB_01470	2.48e-166	-	-	-	P	-	-	-	Major Facilitator Superfamily
DIFHKINB_01471	2.13e-75	-	-	-	P	-	-	-	Major Facilitator Superfamily
DIFHKINB_01472	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
DIFHKINB_01473	1.25e-91	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
DIFHKINB_01474	7.49e-110	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
DIFHKINB_01475	1.18e-124	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
DIFHKINB_01476	4.14e-229	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
DIFHKINB_01477	1.1e-170	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
DIFHKINB_01478	1.55e-309	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
DIFHKINB_01479	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
DIFHKINB_01480	1.37e-220	-	-	-	K	-	-	-	LysR substrate binding domain
DIFHKINB_01481	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
DIFHKINB_01482	0.0	-	-	-	M	-	-	-	domain protein
DIFHKINB_01483	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
DIFHKINB_01484	0.0	-	-	-	S	-	-	-	domain, Protein
DIFHKINB_01485	1.71e-246	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DIFHKINB_01486	1.8e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
DIFHKINB_01487	2.28e-271	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DIFHKINB_01488	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
DIFHKINB_01489	2.88e-229	ydbI	-	-	K	-	-	-	AI-2E family transporter
DIFHKINB_01490	3.66e-54	-	-	-	-	-	-	-	-
DIFHKINB_01491	4.93e-212	-	-	-	S	-	-	-	Alpha beta hydrolase
DIFHKINB_01492	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
DIFHKINB_01493	9.2e-207	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
DIFHKINB_01494	1.29e-54	-	-	-	S	-	-	-	Transglycosylase associated protein
DIFHKINB_01495	3.18e-19	-	-	-	S	-	-	-	CsbD-like
DIFHKINB_01496	1.72e-214	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
DIFHKINB_01497	0.0	fusA1	-	-	J	-	-	-	elongation factor G
DIFHKINB_01498	1.92e-26	-	-	-	-	-	-	-	-
DIFHKINB_01499	4.34e-198	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
DIFHKINB_01500	1.58e-178	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
DIFHKINB_01501	2.7e-169	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
DIFHKINB_01502	6.39e-150	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
DIFHKINB_01503	5.09e-285	-	-	-	S	-	-	-	Sterol carrier protein domain
DIFHKINB_01505	1.39e-256	ydhF	-	-	S	-	-	-	Aldo keto reductase
DIFHKINB_01506	4.18e-118	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
DIFHKINB_01507	7.49e-29	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
DIFHKINB_01508	6.94e-146	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
DIFHKINB_01510	2.64e-151	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
DIFHKINB_01511	0.0	-	-	-	-	-	-	-	-
DIFHKINB_01512	1.19e-280	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
DIFHKINB_01513	2.56e-218	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
DIFHKINB_01514	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
DIFHKINB_01515	8.13e-99	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
DIFHKINB_01516	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
DIFHKINB_01517	8.73e-142	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
DIFHKINB_01518	1.77e-45	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
DIFHKINB_01519	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DIFHKINB_01520	7.47e-112	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DIFHKINB_01521	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
DIFHKINB_01522	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DIFHKINB_01523	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DIFHKINB_01524	4.56e-266	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DIFHKINB_01525	1.04e-27	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
DIFHKINB_01526	2.08e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DIFHKINB_01527	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DIFHKINB_01528	6.59e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
DIFHKINB_01529	3.62e-79	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DIFHKINB_01530	1.7e-201	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DIFHKINB_01531	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DIFHKINB_01532	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DIFHKINB_01533	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
DIFHKINB_01534	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DIFHKINB_01535	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
DIFHKINB_01536	4.49e-266	-	-	-	EGP	-	-	-	Major facilitator Superfamily
DIFHKINB_01537	1.27e-195	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
DIFHKINB_01538	9.66e-138	-	-	-	-	-	-	-	-
DIFHKINB_01539	1.98e-149	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
DIFHKINB_01540	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DIFHKINB_01541	7.94e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
DIFHKINB_01542	2.63e-296	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
DIFHKINB_01543	1.13e-98	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DIFHKINB_01544	1.67e-315	ynbB	-	-	P	-	-	-	aluminum resistance
DIFHKINB_01545	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
DIFHKINB_01546	0.0	-	-	-	E	-	-	-	Amino acid permease
DIFHKINB_01547	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
DIFHKINB_01548	3.17e-200	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
DIFHKINB_01549	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
DIFHKINB_01550	6.31e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
DIFHKINB_01551	4.35e-86	-	-	-	S	-	-	-	Cupredoxin-like domain
DIFHKINB_01552	3.09e-102	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
DIFHKINB_01553	2.26e-117	-	-	-	-	-	-	-	-
DIFHKINB_01554	1.37e-116	-	-	-	-	-	-	-	-
DIFHKINB_01555	8.45e-92	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
DIFHKINB_01556	7.1e-293	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
DIFHKINB_01557	1.58e-60	-	-	-	I	-	-	-	bis(5'-adenosyl)-triphosphatase activity
DIFHKINB_01558	5.76e-296	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
DIFHKINB_01559	1.78e-162	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DIFHKINB_01561	6.61e-295	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
DIFHKINB_01562	1.45e-303	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
DIFHKINB_01563	4.15e-162	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
DIFHKINB_01564	8.74e-155	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
DIFHKINB_01565	1.26e-172	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DIFHKINB_01566	2.53e-206	-	-	-	S	-	-	-	Aldo/keto reductase family
DIFHKINB_01567	7.88e-24	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
DIFHKINB_01568	9.68e-173	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
DIFHKINB_01569	9.42e-202	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DIFHKINB_01570	2.35e-102	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
DIFHKINB_01571	3.73e-22	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
DIFHKINB_01572	1.13e-249	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
DIFHKINB_01573	1.84e-196	-	-	-	S	-	-	-	Putative esterase
DIFHKINB_01574	1.04e-270	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
DIFHKINB_01575	1.05e-203	gspK	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
DIFHKINB_01576	0.0	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DIFHKINB_01577	9.29e-250	-	-	-	V	-	-	-	Beta-lactamase
DIFHKINB_01578	8.85e-226	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
DIFHKINB_01579	2.8e-256	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
DIFHKINB_01580	2.01e-214	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
DIFHKINB_01581	4.97e-313	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
DIFHKINB_01582	1.05e-224	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
DIFHKINB_01583	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DIFHKINB_01584	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
DIFHKINB_01585	1.05e-231	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
DIFHKINB_01586	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
DIFHKINB_01587	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DIFHKINB_01588	7.17e-258	-	-	-	S	-	-	-	DUF218 domain
DIFHKINB_01589	8.24e-137	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DIFHKINB_01590	9.16e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
DIFHKINB_01591	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
DIFHKINB_01592	1.66e-303	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
DIFHKINB_01593	3.9e-147	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
DIFHKINB_01594	1.75e-202	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
DIFHKINB_01595	1.03e-155	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DIFHKINB_01596	8.28e-47	-	-	-	-	-	-	-	-
DIFHKINB_01597	3.3e-36	-	-	-	-	-	-	-	-
DIFHKINB_01598	7.16e-204	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DIFHKINB_01599	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
DIFHKINB_01601	1.39e-257	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
DIFHKINB_01602	0.0	cadA	-	-	P	-	-	-	P-type ATPase
DIFHKINB_01603	2.47e-112	ykuL	-	-	S	-	-	-	(CBS) domain
DIFHKINB_01605	9.94e-60	-	-	-	-	-	-	-	-
DIFHKINB_01606	8.97e-66	-	-	-	-	-	-	-	-
DIFHKINB_01607	7.91e-78	-	-	-	-	-	-	-	-
DIFHKINB_01608	5.68e-260	-	-	-	S	-	-	-	Membrane
DIFHKINB_01609	4.82e-60	-	-	-	-	-	-	-	-
DIFHKINB_01610	9.7e-07	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
DIFHKINB_01611	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DIFHKINB_01612	9.88e-305	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
DIFHKINB_01613	2.11e-49	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DIFHKINB_01614	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DIFHKINB_01615	2.47e-223	pbpX2	-	-	V	-	-	-	Beta-lactamase
DIFHKINB_01616	1.52e-274	-	-	-	E	-	-	-	Major Facilitator Superfamily
DIFHKINB_01617	7.34e-54	-	-	-	-	-	-	-	-
DIFHKINB_01618	4.61e-308	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DIFHKINB_01619	3.55e-199	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DIFHKINB_01620	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
DIFHKINB_01621	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
DIFHKINB_01622	1.51e-236	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
DIFHKINB_01623	1.23e-166	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
DIFHKINB_01624	2.46e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
DIFHKINB_01625	4.26e-86	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
DIFHKINB_01626	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
DIFHKINB_01627	4.12e-311	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
DIFHKINB_01628	1.02e-177	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
DIFHKINB_01629	6.26e-306	-	-	-	E	-	-	-	amino acid
DIFHKINB_01630	3.99e-299	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DIFHKINB_01631	2.39e-246	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
DIFHKINB_01632	1.52e-207	-	-	-	EG	-	-	-	EamA-like transporter family
DIFHKINB_01633	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
DIFHKINB_01634	8.43e-170	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
DIFHKINB_01635	1.38e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
DIFHKINB_01636	2.82e-188	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
DIFHKINB_01637	1.19e-236	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
DIFHKINB_01638	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
DIFHKINB_01639	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DIFHKINB_01640	1.59e-120	ymdB	-	-	S	-	-	-	Macro domain protein
DIFHKINB_01641	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
DIFHKINB_01642	2.4e-160	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
DIFHKINB_01643	1.31e-287	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
DIFHKINB_01644	2.49e-201	-	-	-	-	-	-	-	-
DIFHKINB_01645	5.74e-71	aroD	1.1.1.25, 4.2.1.10	-	E	ko:K03785,ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate dehydratase activity
DIFHKINB_01646	4.62e-223	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
DIFHKINB_01647	9.8e-197	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
DIFHKINB_01648	2.92e-183	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
DIFHKINB_01649	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
DIFHKINB_01650	6.19e-208	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DIFHKINB_01651	4.68e-168	-	-	-	-	-	-	-	-
DIFHKINB_01652	4.81e-69	-	-	-	-	-	-	-	-
DIFHKINB_01653	3.01e-181	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
DIFHKINB_01654	1.58e-138	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
DIFHKINB_01655	1.53e-181	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
DIFHKINB_01656	8.8e-149	-	-	-	G	-	-	-	Phosphoglycerate mutase family
DIFHKINB_01657	9.98e-146	-	-	-	G	-	-	-	phosphoglycerate mutase
DIFHKINB_01658	2.72e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DIFHKINB_01659	2.91e-234	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
DIFHKINB_01660	3.67e-154	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DIFHKINB_01661	5.09e-203	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
DIFHKINB_01662	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DIFHKINB_01663	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DIFHKINB_01664	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DIFHKINB_01665	6.73e-51	-	-	-	-	-	-	-	-
DIFHKINB_01666	6.92e-141	-	-	-	K	-	-	-	WHG domain
DIFHKINB_01667	9.4e-128	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
DIFHKINB_01668	4.45e-128	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
DIFHKINB_01669	3.26e-254	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
DIFHKINB_01670	1.06e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
DIFHKINB_01671	1.33e-227	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DIFHKINB_01672	1.5e-123	cvpA	-	-	S	-	-	-	Colicin V production protein
DIFHKINB_01673	8.33e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
DIFHKINB_01674	1.28e-197	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
DIFHKINB_01675	7.1e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
DIFHKINB_01676	9.01e-198	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
DIFHKINB_01677	2.58e-58	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
DIFHKINB_01678	9.37e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DIFHKINB_01679	3.82e-191	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
DIFHKINB_01680	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
DIFHKINB_01681	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
DIFHKINB_01682	2.39e-156	vanR	-	-	K	-	-	-	response regulator
DIFHKINB_01683	1.85e-264	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
DIFHKINB_01684	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DIFHKINB_01685	1.29e-184	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
DIFHKINB_01686	9.23e-214	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DIFHKINB_01687	1.07e-282	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
DIFHKINB_01688	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
DIFHKINB_01689	2.29e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
DIFHKINB_01690	5.13e-214	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
DIFHKINB_01691	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
DIFHKINB_01692	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DIFHKINB_01693	2.02e-179	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
DIFHKINB_01694	4.8e-57	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
DIFHKINB_01695	3.83e-211	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
DIFHKINB_01696	2.22e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
DIFHKINB_01697	8.87e-174	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
DIFHKINB_01698	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
DIFHKINB_01700	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
DIFHKINB_01701	1.04e-271	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
DIFHKINB_01702	5.64e-54	-	-	-	-	-	-	-	-
DIFHKINB_01703	9.18e-83	-	-	-	-	-	-	-	-
DIFHKINB_01704	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
DIFHKINB_01705	9.33e-179	-	-	-	S	-	-	-	Putative threonine/serine exporter
DIFHKINB_01706	1.1e-103	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
DIFHKINB_01707	5.2e-54	-	-	-	-	-	-	-	-
DIFHKINB_01708	1.26e-77	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
DIFHKINB_01709	6.76e-106	-	-	-	-	-	-	-	-
DIFHKINB_01710	3.52e-232	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DIFHKINB_01711	7.8e-107	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
DIFHKINB_01712	3.86e-143	-	-	-	-	-	-	-	-
DIFHKINB_01713	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
DIFHKINB_01714	3.52e-58	-	-	-	-	-	-	-	-
DIFHKINB_01715	5.01e-128	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
DIFHKINB_01717	1.19e-176	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
DIFHKINB_01718	4.24e-298	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
DIFHKINB_01719	3.7e-299	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DIFHKINB_01720	0.0	-	-	-	E	-	-	-	Amino Acid
DIFHKINB_01721	4.63e-173	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DIFHKINB_01722	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
DIFHKINB_01723	6.19e-162	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
DIFHKINB_01724	2.45e-34	-	-	-	-	-	-	-	-
DIFHKINB_01725	5.76e-70	-	-	-	-	-	-	-	-
DIFHKINB_01726	6.23e-191	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
DIFHKINB_01727	0.0	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
DIFHKINB_01728	2.81e-165	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DIFHKINB_01729	1.38e-186	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
DIFHKINB_01730	4.84e-60	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
DIFHKINB_01731	0.0	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
DIFHKINB_01732	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
DIFHKINB_01734	7.5e-153	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
DIFHKINB_01735	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
DIFHKINB_01736	9.08e-176	-	-	-	S	-	-	-	Peptidase_C39 like family
DIFHKINB_01737	1.97e-159	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
DIFHKINB_01738	4.36e-105	-	-	-	L	-	-	-	MgsA AAA+ ATPase C terminal
DIFHKINB_01739	3.14e-311	lacE	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DIFHKINB_01740	3.93e-134	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
DIFHKINB_01741	7.9e-212	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
DIFHKINB_01742	3.93e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DIFHKINB_01743	6.01e-262	-	-	-	M	-	-	-	Rib/alpha-like repeat
DIFHKINB_01744	1.61e-118	-	-	-	M	-	-	-	Rib/alpha-like repeat
DIFHKINB_01745	7.94e-202	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
DIFHKINB_01746	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DIFHKINB_01747	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
DIFHKINB_01748	2.22e-206	-	-	-	EG	-	-	-	EamA-like transporter family
DIFHKINB_01749	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
DIFHKINB_01750	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
DIFHKINB_01751	1.73e-89	-	-	-	-	-	-	-	-
DIFHKINB_01752	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DIFHKINB_01753	4.41e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DIFHKINB_01754	1.01e-274	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
DIFHKINB_01755	4.1e-302	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DIFHKINB_01756	4.63e-169	-	-	-	S	-	-	-	PAS domain
DIFHKINB_01757	5.83e-205	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
DIFHKINB_01758	1.11e-70	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DIFHKINB_01759	2.34e-06	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DIFHKINB_01760	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DIFHKINB_01761	1.7e-188	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
DIFHKINB_01762	1.83e-124	-	-	-	S	-	-	-	PAS domain
DIFHKINB_01763	3.53e-314	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
DIFHKINB_01764	1.16e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
DIFHKINB_01765	7.18e-145	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
DIFHKINB_01766	5.38e-180	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DIFHKINB_01767	1.2e-236	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
DIFHKINB_01769	3.16e-148	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
DIFHKINB_01770	8.33e-189	dkgB	-	-	S	-	-	-	reductase
DIFHKINB_01771	1.46e-202	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
DIFHKINB_01772	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DIFHKINB_01773	9.81e-259	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
DIFHKINB_01774	4.34e-202	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
DIFHKINB_01775	3.39e-189	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DIFHKINB_01776	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
DIFHKINB_01777	1.38e-311	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
DIFHKINB_01778	7.83e-74	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
DIFHKINB_01779	1.84e-100	yybA	-	-	K	-	-	-	Transcriptional regulator
DIFHKINB_01780	2.29e-125	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
DIFHKINB_01781	1.27e-104	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
DIFHKINB_01782	1.59e-214	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
DIFHKINB_01783	8.18e-216	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
DIFHKINB_01784	3.6e-127	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DIFHKINB_01785	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
DIFHKINB_01786	8.84e-169	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
DIFHKINB_01787	6.22e-156	-	-	-	S	-	-	-	SNARE associated Golgi protein
DIFHKINB_01788	1.05e-229	-	-	-	-	-	-	-	-
DIFHKINB_01789	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
DIFHKINB_01790	1.73e-184	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
DIFHKINB_01791	7.51e-195	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DIFHKINB_01792	1.03e-138	-	-	-	S	-	-	-	SNARE associated Golgi protein
DIFHKINB_01793	3.29e-132	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
DIFHKINB_01794	1.3e-301	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DIFHKINB_01795	2.37e-79	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
DIFHKINB_01796	2.17e-230	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
DIFHKINB_01797	1.45e-151	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
DIFHKINB_01798	1.62e-135	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
DIFHKINB_01799	4.87e-190	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DIFHKINB_01800	1.44e-127	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
DIFHKINB_01801	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
DIFHKINB_01802	3.99e-74	-	-	-	-	-	-	-	-
DIFHKINB_01803	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
DIFHKINB_01804	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
DIFHKINB_01805	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
DIFHKINB_01806	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
DIFHKINB_01807	2.52e-229	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
DIFHKINB_01808	1.54e-270	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
DIFHKINB_01809	1.47e-67	-	-	-	-	-	-	-	-
DIFHKINB_01810	2.54e-33	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DIFHKINB_01811	1.51e-203	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
DIFHKINB_01812	1.06e-280	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DIFHKINB_01813	4.91e-150	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DIFHKINB_01814	1.14e-186	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
DIFHKINB_01815	2.57e-90	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
DIFHKINB_01816	8.93e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
DIFHKINB_01817	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DIFHKINB_01818	1.33e-118	cvpA	-	-	S	-	-	-	Colicin V production protein
DIFHKINB_01819	1.27e-66	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
DIFHKINB_01820	1.01e-95	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DIFHKINB_01821	1.08e-56	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
DIFHKINB_01822	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DIFHKINB_01823	9.03e-298	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DIFHKINB_01824	2.44e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
DIFHKINB_01825	1.79e-267	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DIFHKINB_01826	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DIFHKINB_01827	1.08e-67	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
DIFHKINB_01828	1.16e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DIFHKINB_01829	1.26e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DIFHKINB_01830	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DIFHKINB_01831	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DIFHKINB_01832	0.0	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
DIFHKINB_01833	4.8e-77	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
DIFHKINB_01850	1.09e-79	-	-	-	-	-	-	-	-
DIFHKINB_01862	2.31e-281	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
DIFHKINB_01863	3.53e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
DIFHKINB_01864	3.15e-232	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DIFHKINB_01865	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily