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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HMCAFHEB_00001	2.47e-273	-	-	-	GK	-	-	-	ROK family
HMCAFHEB_00002	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
HMCAFHEB_00003	4.22e-206	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Phosphotransferase enzyme family
HMCAFHEB_00005	3.34e-69	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HMCAFHEB_00006	1.98e-148	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
HMCAFHEB_00007	2.45e-95	-	-	-	S	-	-	-	domain protein
HMCAFHEB_00008	5.55e-68	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMCAFHEB_00010	9.73e-206	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HMCAFHEB_00011	1.72e-170	-	-	-	P	-	-	-	NMT1/THI5 like
HMCAFHEB_00012	2.08e-152	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HMCAFHEB_00013	3.14e-42	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HMCAFHEB_00014	6.65e-18	-	-	-	L	-	-	-	Transposase
HMCAFHEB_00015	1.2e-131	-	-	-	K	-	-	-	cell envelope-related transcriptional attenuator
HMCAFHEB_00017	0.0	-	-	-	-	-	-	-	-
HMCAFHEB_00018	2.49e-230	-	-	-	S	ko:K21688	-	ko00000	G5
HMCAFHEB_00019	2.57e-78	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
HMCAFHEB_00020	8.16e-154	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
HMCAFHEB_00021	1.03e-205	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HMCAFHEB_00023	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HMCAFHEB_00024	2.17e-93	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HMCAFHEB_00025	0.0	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
HMCAFHEB_00026	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
HMCAFHEB_00027	2.09e-244	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HMCAFHEB_00028	7.33e-150	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
HMCAFHEB_00029	4.67e-173	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HMCAFHEB_00030	0.0	pon1	-	-	M	-	-	-	Transglycosylase
HMCAFHEB_00031	7.42e-278	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
HMCAFHEB_00032	2.85e-289	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HMCAFHEB_00033	4.27e-186	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HMCAFHEB_00034	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
HMCAFHEB_00035	1.14e-294	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
HMCAFHEB_00036	3.8e-308	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HMCAFHEB_00037	3.23e-58	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HMCAFHEB_00038	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HMCAFHEB_00039	1.62e-93	-	-	-	-	-	-	-	-
HMCAFHEB_00041	9.1e-157	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMCAFHEB_00042	2.66e-09	exsH	3.2.1.178, 3.2.1.18, 3.2.1.52	GH16,GH20,GH33	G	ko:K01186,ko:K12373,ko:K20830	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko02042,ko03110	xyloglucan:xyloglucosyl transferase activity
HMCAFHEB_00043	6.87e-60	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	Putative cell wall binding repeat
HMCAFHEB_00044	6.01e-235	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
HMCAFHEB_00045	9.62e-145	-	-	-	-	-	-	-	-
HMCAFHEB_00046	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMCAFHEB_00047	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMCAFHEB_00048	1.08e-123	-	-	-	T	-	-	-	Forkhead associated domain
HMCAFHEB_00049	5.65e-101	-	-	-	B	-	-	-	Belongs to the OprB family
HMCAFHEB_00050	5.53e-210	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
HMCAFHEB_00051	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HMCAFHEB_00052	1.92e-300	-	-	-	S	-	-	-	Protein of unknown function DUF58
HMCAFHEB_00053	0.0	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HMCAFHEB_00054	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
HMCAFHEB_00055	0.0	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HMCAFHEB_00056	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
HMCAFHEB_00057	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
HMCAFHEB_00058	6.85e-195	-	-	-	K	-	-	-	-acetyltransferase
HMCAFHEB_00059	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
HMCAFHEB_00060	1.03e-55	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
HMCAFHEB_00061	3.83e-13	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
HMCAFHEB_00062	3.22e-33	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HMCAFHEB_00063	2.52e-78	-	-	-	L	-	-	-	Transposase
HMCAFHEB_00064	3.34e-169	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HMCAFHEB_00065	6.97e-208	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMCAFHEB_00066	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMCAFHEB_00067	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
HMCAFHEB_00068	7.28e-207	-	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	elongation factor G
HMCAFHEB_00069	3.15e-162	-	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	elongation factor G
HMCAFHEB_00070	9.61e-313	vpr	-	-	O	-	-	-	Subtilase family
HMCAFHEB_00071	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMCAFHEB_00072	6.43e-160	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMCAFHEB_00073	0.0	-	-	-	S	-	-	-	zinc finger
HMCAFHEB_00074	5.72e-128	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HMCAFHEB_00075	7.65e-293	aspB	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class-V
HMCAFHEB_00076	5.3e-200	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HMCAFHEB_00077	2.28e-169	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
HMCAFHEB_00078	8.74e-193	thiF	2.7.7.73, 2.7.7.80, 2.8.1.11	-	H	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
HMCAFHEB_00079	0.0	-	-	-	OP	-	-	-	Sulfurtransferase TusA
HMCAFHEB_00080	2.73e-233	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HMCAFHEB_00082	1.41e-217	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
HMCAFHEB_00083	1.47e-56	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMCAFHEB_00084	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMCAFHEB_00085	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
HMCAFHEB_00086	1.11e-178	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMCAFHEB_00087	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
HMCAFHEB_00088	3.9e-213	-	-	-	-	-	-	-	-
HMCAFHEB_00089	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
HMCAFHEB_00090	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
HMCAFHEB_00092	4.46e-118	-	-	-	K	-	-	-	MarR family
HMCAFHEB_00093	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HMCAFHEB_00094	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HMCAFHEB_00095	2.64e-219	-	-	-	S	-	-	-	Patatin-like phospholipase
HMCAFHEB_00096	1.35e-196	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HMCAFHEB_00097	6.27e-217	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HMCAFHEB_00098	2.91e-148	-	-	-	S	-	-	-	Vitamin K epoxide reductase
HMCAFHEB_00099	3.62e-213	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
HMCAFHEB_00100	9.31e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
HMCAFHEB_00101	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
HMCAFHEB_00102	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HMCAFHEB_00103	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HMCAFHEB_00104	2.49e-194	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HMCAFHEB_00105	2.24e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
HMCAFHEB_00106	4.8e-249	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HMCAFHEB_00107	1.52e-81	-	-	-	S	-	-	-	Thiamine-binding protein
HMCAFHEB_00108	1.21e-209	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HMCAFHEB_00109	3.43e-291	-	-	-	O	ko:K13525	ko04141,ko05134,map04141,map05134	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	AAA domain (Cdc48 subfamily)
HMCAFHEB_00110	1.62e-110	-	-	-	-	-	-	-	-
HMCAFHEB_00111	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HMCAFHEB_00112	1.5e-203	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HMCAFHEB_00113	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
HMCAFHEB_00114	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
HMCAFHEB_00115	4.69e-314	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMCAFHEB_00116	8.03e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMCAFHEB_00117	9.4e-105	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HMCAFHEB_00118	1.35e-56	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HMCAFHEB_00119	1.65e-191	-	-	-	V	-	-	-	DivIVA protein
HMCAFHEB_00120	4.6e-148	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HMCAFHEB_00121	2.68e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HMCAFHEB_00123	1.25e-82	-	-	-	-	-	-	-	-
HMCAFHEB_00124	2.62e-220	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HMCAFHEB_00125	5.51e-263	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HMCAFHEB_00126	1.65e-305	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
HMCAFHEB_00127	4.29e-203	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
HMCAFHEB_00128	2.15e-284	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
HMCAFHEB_00129	1.38e-103	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HMCAFHEB_00130	1.06e-185	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
HMCAFHEB_00131	5.45e-60	-	-	-	-	-	-	-	-
HMCAFHEB_00132	2.3e-30	-	-	-	-	-	-	-	-
HMCAFHEB_00134	1.28e-309	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
HMCAFHEB_00135	2.16e-282	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HMCAFHEB_00136	3.99e-298	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HMCAFHEB_00137	0.0	-	-	-	I	-	-	-	acetylesterase activity
HMCAFHEB_00138	3.39e-181	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HMCAFHEB_00139	1.03e-197	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMCAFHEB_00140	5.54e-244	-	-	-	S	-	-	-	Domain of unknown function (DUF1963)
HMCAFHEB_00141	3.11e-25	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HMCAFHEB_00142	1.11e-53	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HMCAFHEB_00143	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
HMCAFHEB_00144	1.07e-163	-	-	-	S	-	-	-	zinc-ribbon domain
HMCAFHEB_00145	1.34e-62	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
HMCAFHEB_00146	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
HMCAFHEB_00147	0.000175	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMCAFHEB_00149	2.5e-258	-	-	-	K	-	-	-	WYL domain
HMCAFHEB_00150	5.5e-199	-	-	-	S	-	-	-	Aldo/keto reductase family
HMCAFHEB_00151	5.19e-222	dkgV	-	-	C	-	-	-	Aldo/keto reductase family
HMCAFHEB_00152	1.5e-100	-	-	-	S	-	-	-	Domain of unknown function (DUF4186)
HMCAFHEB_00155	2.68e-232	-	-	-	S	-	-	-	Protein conserved in bacteria
HMCAFHEB_00156	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HMCAFHEB_00157	4.36e-284	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HMCAFHEB_00158	1.08e-145	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
HMCAFHEB_00159	8.75e-150	-	-	-	-	-	-	-	-
HMCAFHEB_00160	3.31e-157	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HMCAFHEB_00161	4.81e-167	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
HMCAFHEB_00162	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2252)
HMCAFHEB_00163	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HMCAFHEB_00164	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
HMCAFHEB_00165	4.75e-80	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator Superfamily
HMCAFHEB_00166	8.85e-244	-	-	-	M	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HMCAFHEB_00167	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
HMCAFHEB_00168	7.21e-157	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
HMCAFHEB_00169	2.31e-46	-	-	-	-	-	-	-	-
HMCAFHEB_00170	7.29e-134	-	-	-	-	-	-	-	-
HMCAFHEB_00171	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HMCAFHEB_00172	1.13e-225	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HMCAFHEB_00173	4.53e-212	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMCAFHEB_00174	3.03e-166	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HMCAFHEB_00175	2.4e-65	-	-	-	M	-	-	-	Lysin motif
HMCAFHEB_00176	3.85e-108	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMCAFHEB_00177	3.23e-290	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HMCAFHEB_00178	0.0	-	-	-	L	-	-	-	DNA helicase
HMCAFHEB_00179	8.85e-118	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HMCAFHEB_00180	2.17e-246	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMCAFHEB_00181	1.96e-97	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HMCAFHEB_00182	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
HMCAFHEB_00183	2.48e-231	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMCAFHEB_00184	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HMCAFHEB_00185	8.76e-261	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMCAFHEB_00186	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMCAFHEB_00187	1.35e-298	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
HMCAFHEB_00188	1.1e-276	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMCAFHEB_00189	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HMCAFHEB_00190	1.06e-234	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
HMCAFHEB_00193	1.96e-107	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HMCAFHEB_00194	6.45e-302	-	-	-	G	-	-	-	Major Facilitator Superfamily
HMCAFHEB_00195	2.87e-217	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HMCAFHEB_00196	5.33e-286	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HMCAFHEB_00197	3.42e-169	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HMCAFHEB_00198	2.9e-276	-	-	-	GK	-	-	-	ROK family
HMCAFHEB_00199	5.93e-196	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMCAFHEB_00200	2.55e-308	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
HMCAFHEB_00201	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HMCAFHEB_00202	5.3e-243	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMCAFHEB_00203	7.55e-249	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMCAFHEB_00204	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HMCAFHEB_00205	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
HMCAFHEB_00206	7.52e-126	-	-	-	F	-	-	-	NUDIX domain
HMCAFHEB_00208	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
HMCAFHEB_00209	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HMCAFHEB_00210	1.46e-165	-	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HMCAFHEB_00211	6.99e-307	-	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp
HMCAFHEB_00212	7.95e-292	-	2.6.1.33	-	M	ko:K20429	-	ko00000,ko01000	DegT/DnrJ/EryC1/StrS aminotransferase family
HMCAFHEB_00213	3.61e-244	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
HMCAFHEB_00214	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMCAFHEB_00215	2.85e-148	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HMCAFHEB_00216	3.35e-84	-	-	-	-	-	-	-	-
HMCAFHEB_00217	7.58e-248	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HMCAFHEB_00218	2.1e-227	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HMCAFHEB_00220	2.47e-118	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HMCAFHEB_00221	3.39e-254	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMCAFHEB_00222	3.41e-172	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
HMCAFHEB_00224	4.36e-39	-	-	-	S	-	-	-	Spermine/spermidine synthase domain
HMCAFHEB_00225	3.07e-137	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HMCAFHEB_00226	3.31e-35	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
HMCAFHEB_00227	1.29e-79	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMCAFHEB_00228	9.73e-228	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
HMCAFHEB_00229	1.31e-194	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HMCAFHEB_00230	1.68e-193	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMCAFHEB_00231	1.17e-126	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HMCAFHEB_00232	5.17e-192	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
HMCAFHEB_00233	0.0	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HMCAFHEB_00234	0.0	nadB	1.4.3.16, 2.4.2.19	-	H	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HMCAFHEB_00235	3.33e-211	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
HMCAFHEB_00236	2.15e-299	iscS1	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
HMCAFHEB_00237	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
HMCAFHEB_00238	1.29e-109	-	-	-	-	-	-	-	-
HMCAFHEB_00239	7.12e-254	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HMCAFHEB_00240	1.48e-245	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
HMCAFHEB_00241	2.67e-56	-	-	-	-	-	-	-	-
HMCAFHEB_00242	3.89e-235	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HMCAFHEB_00243	4.8e-226	oppB1	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMCAFHEB_00244	3.06e-211	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HMCAFHEB_00245	0.0	oppD	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HMCAFHEB_00246	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HMCAFHEB_00247	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HMCAFHEB_00248	2.87e-215	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
HMCAFHEB_00249	2.19e-195	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
HMCAFHEB_00250	3.77e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
HMCAFHEB_00251	1.9e-315	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMCAFHEB_00252	1.64e-142	-	-	-	-	-	-	-	-
HMCAFHEB_00253	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HMCAFHEB_00254	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HMCAFHEB_00256	1.05e-219	-	-	-	S	-	-	-	Protein conserved in bacteria
HMCAFHEB_00257	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HMCAFHEB_00258	9.87e-70	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HMCAFHEB_00259	7.86e-285	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMCAFHEB_00260	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMCAFHEB_00261	3.86e-174	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HMCAFHEB_00262	3.7e-233	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMCAFHEB_00263	5.22e-176	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
HMCAFHEB_00264	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
HMCAFHEB_00265	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
HMCAFHEB_00266	1.98e-203	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
HMCAFHEB_00267	1.05e-28	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
HMCAFHEB_00268	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HMCAFHEB_00269	4.7e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
HMCAFHEB_00270	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
HMCAFHEB_00271	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
HMCAFHEB_00272	0.0	-	-	-	S	-	-	-	PGAP1-like protein
HMCAFHEB_00274	3.59e-113	-	-	-	-	-	-	-	-
HMCAFHEB_00275	2.23e-195	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HMCAFHEB_00276	7.9e-247	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HMCAFHEB_00277	1.78e-121	-	-	-	-	-	-	-	-
HMCAFHEB_00278	7.12e-229	-	-	-	S	-	-	-	Protein of unknown function DUF58
HMCAFHEB_00279	7.07e-251	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HMCAFHEB_00280	7.48e-185	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HMCAFHEB_00281	1.53e-100	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
HMCAFHEB_00282	2.97e-41	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HMCAFHEB_00283	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMCAFHEB_00284	8.25e-53	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
HMCAFHEB_00285	3.13e-228	-	-	-	-	-	-	-	-
HMCAFHEB_00286	1.23e-171	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
HMCAFHEB_00287	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HMCAFHEB_00288	1.23e-87	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HMCAFHEB_00289	8.61e-251	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
HMCAFHEB_00290	2.42e-237	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
HMCAFHEB_00291	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
HMCAFHEB_00295	5.26e-302	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
HMCAFHEB_00296	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
HMCAFHEB_00297	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HMCAFHEB_00298	2.33e-109	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HMCAFHEB_00299	1.59e-120	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
HMCAFHEB_00300	2.08e-180	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
HMCAFHEB_00301	5.91e-196	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HMCAFHEB_00302	8.52e-144	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMCAFHEB_00303	6.57e-253	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMCAFHEB_00304	2.9e-254	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HMCAFHEB_00305	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
HMCAFHEB_00306	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
HMCAFHEB_00308	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HMCAFHEB_00309	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HMCAFHEB_00310	3.41e-136	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HMCAFHEB_00312	5.64e-179	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HMCAFHEB_00313	3.37e-270	-	-	-	E	-	-	-	Aminotransferase class I and II
HMCAFHEB_00314	3.64e-177	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HMCAFHEB_00315	2.7e-77	-	2.8.2.22	-	S	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HMCAFHEB_00316	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMCAFHEB_00317	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HMCAFHEB_00318	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMCAFHEB_00319	2.75e-268	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HMCAFHEB_00320	7.06e-204	-	-	-	S	-	-	-	Protein conserved in bacteria
HMCAFHEB_00321	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HMCAFHEB_00322	3.01e-182	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
HMCAFHEB_00323	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HMCAFHEB_00324	2.07e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
HMCAFHEB_00325	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
HMCAFHEB_00326	4.36e-244	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
HMCAFHEB_00327	2.07e-195	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HMCAFHEB_00328	3.96e-253	-	-	-	-	-	-	-	-
HMCAFHEB_00329	6.64e-296	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HMCAFHEB_00330	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
HMCAFHEB_00331	8.32e-263	-	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMCAFHEB_00332	0.0	-	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMCAFHEB_00333	1.65e-260	-	-	-	I	ko:K13663	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
HMCAFHEB_00335	2.58e-165	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HMCAFHEB_00336	1.21e-252	-	-	-	GM	-	-	-	GDP-mannose 4,6 dehydratase
HMCAFHEB_00337	5.93e-195	-	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HMCAFHEB_00338	1.97e-186	rfbB2	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HMCAFHEB_00339	3.71e-126	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HMCAFHEB_00340	3.48e-146	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HMCAFHEB_00341	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMCAFHEB_00342	0.0	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000,ko01007	chorismate binding enzyme
HMCAFHEB_00343	2.04e-194	pabC	2.6.1.42, 2.6.1.85, 4.1.3.38	-	E	ko:K00826,ko:K01665,ko:K02619,ko:K03342	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	branched-chain-amino-acid transaminase activity
HMCAFHEB_00344	7.41e-315	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMCAFHEB_00345	1.03e-131	-	-	-	D	-	-	-	Septum formation initiator
HMCAFHEB_00346	6.25e-138	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
HMCAFHEB_00347	5.06e-235	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HMCAFHEB_00349	2.65e-127	-	-	-	-	-	-	-	-
HMCAFHEB_00350	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
HMCAFHEB_00351	7.02e-94	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
HMCAFHEB_00352	1.67e-104	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMCAFHEB_00354	1.31e-191	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
HMCAFHEB_00355	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HMCAFHEB_00356	6.69e-61	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HMCAFHEB_00357	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
HMCAFHEB_00358	0.0	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HMCAFHEB_00359	2.82e-72	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HMCAFHEB_00360	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
HMCAFHEB_00361	0.0	-	-	-	-	-	-	-	-
HMCAFHEB_00362	1.05e-85	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HMCAFHEB_00363	3.31e-200	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
HMCAFHEB_00364	1.82e-165	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
HMCAFHEB_00365	1.85e-92	umuD	-	-	KT	ko:K03503	-	ko00000,ko01000,ko01002,ko03400	Peptidase S24-like
HMCAFHEB_00366	5.91e-259	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HMCAFHEB_00367	5.39e-163	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
HMCAFHEB_00368	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HMCAFHEB_00369	1.99e-131	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
HMCAFHEB_00370	8.94e-109	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HMCAFHEB_00371	2.15e-177	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
HMCAFHEB_00372	2.33e-209	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMCAFHEB_00373	2.69e-233	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HMCAFHEB_00374	1.65e-208	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMCAFHEB_00375	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HMCAFHEB_00376	2.24e-139	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMCAFHEB_00377	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMCAFHEB_00378	4.13e-230	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
HMCAFHEB_00379	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
HMCAFHEB_00380	4.9e-142	aspA	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HMCAFHEB_00382	5.44e-161	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
HMCAFHEB_00383	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMCAFHEB_00384	6.29e-220	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
HMCAFHEB_00385	2.5e-158	-	-	-	L	-	-	-	NUDIX domain
HMCAFHEB_00386	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HMCAFHEB_00387	4.17e-280	-	-	-	-	-	-	-	-
HMCAFHEB_00389	2.8e-169	-	-	-	L	-	-	-	Phage integrase family
HMCAFHEB_00390	3.58e-142	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
HMCAFHEB_00391	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HMCAFHEB_00392	8.03e-296	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMCAFHEB_00393	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
HMCAFHEB_00394	2.7e-55	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HMCAFHEB_00395	5.93e-17	-	-	-	L	-	-	-	Helix-turn-helix domain
HMCAFHEB_00396	5.05e-129	-	-	-	L	-	-	-	AAA ATPase domain
HMCAFHEB_00397	1.04e-54	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD/REP helicase N-terminal domain
HMCAFHEB_00398	1.46e-37	-	-	-	-	-	-	-	-
HMCAFHEB_00399	1.76e-18	-	-	-	-	-	-	-	-
HMCAFHEB_00400	2.68e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
HMCAFHEB_00401	1.24e-236	-	-	-	S	-	-	-	Protein of unknown function DUF262
HMCAFHEB_00403	6.93e-87	-	-	-	L	-	-	-	Integrase core domain
HMCAFHEB_00404	5.06e-46	-	-	-	L	-	-	-	Transposase
HMCAFHEB_00405	1.48e-232	-	-	-	-	-	-	-	-
HMCAFHEB_00406	1.53e-33	-	-	-	-	-	-	-	-
HMCAFHEB_00407	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HMCAFHEB_00408	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HMCAFHEB_00409	7.55e-243	pitB	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
HMCAFHEB_00410	4.91e-150	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
HMCAFHEB_00411	3.95e-156	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HMCAFHEB_00412	3.98e-239	-	-	-	T	-	-	-	Histidine kinase
HMCAFHEB_00413	1.06e-57	pacL	3.6.3.8, 3.6.3.9	-	P	ko:K01537,ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	ko00000,ko00001,ko01000,ko04147	ATPase, P-type transporting, HAD superfamily, subfamily IC
HMCAFHEB_00414	1.75e-228	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMCAFHEB_00415	2.77e-290	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HMCAFHEB_00416	0.0	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HMCAFHEB_00417	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HMCAFHEB_00418	2.21e-254	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HMCAFHEB_00420	3.34e-102	-	-	-	-	-	-	-	-
HMCAFHEB_00421	7.23e-85	-	-	-	D	-	-	-	MobA/MobL family
HMCAFHEB_00422	9e-64	-	-	-	L	ko:K07483	-	ko00000	Transposase
HMCAFHEB_00423	1.18e-222	tnp3521a2	-	-	L	-	-	-	Integrase core domain
HMCAFHEB_00424	5.58e-33	-	-	-	S	-	-	-	Adenine-specific methyltransferase EcoRI
HMCAFHEB_00425	2.28e-53	-	-	-	-	-	-	-	-
HMCAFHEB_00426	4.2e-145	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
HMCAFHEB_00428	2.02e-141	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMCAFHEB_00429	6.6e-54	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMCAFHEB_00431	4.79e-307	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
HMCAFHEB_00432	6.52e-139	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HMCAFHEB_00433	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HMCAFHEB_00434	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HMCAFHEB_00435	1.22e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
HMCAFHEB_00436	1.54e-270	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HMCAFHEB_00437	5.47e-172	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HMCAFHEB_00438	1.83e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HMCAFHEB_00439	0.0	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HMCAFHEB_00440	7.56e-174	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
HMCAFHEB_00441	4.03e-85	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
HMCAFHEB_00442	7.33e-50	-	-	-	-	-	-	-	-
HMCAFHEB_00443	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMCAFHEB_00444	6.58e-99	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMCAFHEB_00445	2e-250	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HMCAFHEB_00446	5.3e-69	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
HMCAFHEB_00447	1.57e-280	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HMCAFHEB_00448	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HMCAFHEB_00449	1.6e-103	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HMCAFHEB_00450	4.78e-138	-	-	-	-	-	-	-	-
HMCAFHEB_00451	9.91e-154	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HMCAFHEB_00452	7.15e-06	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase (surface protein transpeptidase)
HMCAFHEB_00453	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMCAFHEB_00454	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
HMCAFHEB_00455	1.19e-297	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
HMCAFHEB_00456	2.13e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HMCAFHEB_00457	2.09e-305	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HMCAFHEB_00458	4.14e-132	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HMCAFHEB_00459	1.94e-136	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HMCAFHEB_00460	1.42e-308	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HMCAFHEB_00461	1.78e-208	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
HMCAFHEB_00463	2.09e-173	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HMCAFHEB_00464	1.37e-76	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HMCAFHEB_00465	1.05e-253	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
HMCAFHEB_00466	1.82e-130	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMCAFHEB_00467	0.0	corC	-	-	S	-	-	-	CBS domain
HMCAFHEB_00468	1.45e-236	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HMCAFHEB_00469	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HMCAFHEB_00470	6.9e-259	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
HMCAFHEB_00471	1.08e-58	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
HMCAFHEB_00472	8.15e-305	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HMCAFHEB_00473	4.21e-242	-	-	-	S	ko:K06889	-	ko00000	alpha beta
HMCAFHEB_00474	1.66e-128	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HMCAFHEB_00475	1.11e-287	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
HMCAFHEB_00476	2.34e-61	-	-	-	S	-	-	-	phosphoesterase or phosphohydrolase
HMCAFHEB_00477	2.76e-125	-	-	-	T	-	-	-	RNA ligase
HMCAFHEB_00478	4.63e-175	-	-	-	S	-	-	-	UPF0126 domain
HMCAFHEB_00479	3.91e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HMCAFHEB_00480	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMCAFHEB_00481	3.85e-311	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HMCAFHEB_00482	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
HMCAFHEB_00483	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
HMCAFHEB_00484	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
HMCAFHEB_00485	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HMCAFHEB_00486	5.23e-107	-	-	-	-	-	-	-	-
HMCAFHEB_00487	2.88e-313	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
HMCAFHEB_00488	3.3e-231	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HMCAFHEB_00489	1.5e-191	-	-	-	S	ko:K11206	-	ko00000,ko01000	Carbon-nitrogen hydrolase
HMCAFHEB_00490	1.33e-64	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
HMCAFHEB_00491	1.07e-237	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HMCAFHEB_00492	7.56e-47	-	-	-	L	-	-	-	Helix-turn-helix domain
HMCAFHEB_00493	1.4e-137	-	-	-	S	-	-	-	Short C-terminal domain
HMCAFHEB_00494	7.91e-235	-	-	-	L	ko:K07485	-	ko00000	Transposase
HMCAFHEB_00495	0.0	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HMCAFHEB_00496	1.61e-40	-	-	-	-	-	-	-	-
HMCAFHEB_00497	2.36e-99	-	-	-	E	-	-	-	Rard protein
HMCAFHEB_00498	1.17e-34	-	-	-	S	-	-	-	Rard protein
HMCAFHEB_00499	7.7e-226	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HMCAFHEB_00500	4.92e-266	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HMCAFHEB_00501	8.29e-129	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
HMCAFHEB_00502	2.44e-309	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HMCAFHEB_00503	7.01e-31	-	-	-	-	-	-	-	-
HMCAFHEB_00504	2.51e-45	-	-	-	-	-	-	-	-
HMCAFHEB_00505	7.76e-297	-	-	-	S	-	-	-	Protein of unknown function DUF262
HMCAFHEB_00506	1.9e-66	-	-	-	-	-	-	-	-
HMCAFHEB_00507	7.91e-132	-	-	-	S	-	-	-	Virulence protein RhuM family
HMCAFHEB_00508	7.23e-73	-	-	-	-	-	-	-	-
HMCAFHEB_00509	1.93e-46	-	-	-	-	-	-	-	-
HMCAFHEB_00510	7.08e-68	-	-	-	-	-	-	-	-
HMCAFHEB_00511	2.15e-168	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
HMCAFHEB_00514	6.36e-50	-	-	-	-	-	-	-	-
HMCAFHEB_00516	3.1e-51	-	-	-	-	-	-	-	-
HMCAFHEB_00518	4.15e-120	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
HMCAFHEB_00519	0.0	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
HMCAFHEB_00520	1.29e-207	-	-	-	K	-	-	-	Transcriptional regulator
HMCAFHEB_00521	6.46e-37	-	-	-	-	-	-	-	-
HMCAFHEB_00522	1.25e-105	-	-	-	V	-	-	-	HNH endonuclease
HMCAFHEB_00523	5.17e-138	-	-	-	A	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HMCAFHEB_00525	1.15e-61	-	-	-	-	-	-	-	-
HMCAFHEB_00527	8.05e-179	-	-	-	-	-	-	-	-
HMCAFHEB_00528	1.81e-46	-	-	-	N	-	-	-	HicA toxin of bacterial toxin-antitoxin,
HMCAFHEB_00529	2.96e-96	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
HMCAFHEB_00530	5.69e-44	-	-	-	K	-	-	-	Transcriptional regulator
HMCAFHEB_00533	1.14e-86	-	-	-	-	ko:K07451	-	ko00000,ko01000,ko02048	-
HMCAFHEB_00534	1.32e-148	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
HMCAFHEB_00535	1.89e-91	-	-	-	-	-	-	-	-
HMCAFHEB_00536	0.0	-	-	-	S	-	-	-	Terminase
HMCAFHEB_00537	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HMCAFHEB_00538	3.18e-304	-	-	-	-	-	-	-	-
HMCAFHEB_00539	2.73e-58	-	-	-	-	-	-	-	-
HMCAFHEB_00540	2.47e-125	-	-	-	-	-	-	-	-
HMCAFHEB_00541	7.08e-225	-	-	-	S	-	-	-	Phage capsid family
HMCAFHEB_00542	3.74e-85	-	-	-	-	-	-	-	-
HMCAFHEB_00543	4.24e-119	-	-	-	-	-	-	-	-
HMCAFHEB_00544	3.65e-103	-	-	-	-	-	-	-	-
HMCAFHEB_00545	6.59e-96	-	-	-	-	-	-	-	-
HMCAFHEB_00546	9.53e-93	-	-	-	-	-	-	-	-
HMCAFHEB_00547	1.44e-122	-	-	-	-	-	-	-	-
HMCAFHEB_00548	1.11e-108	-	-	-	-	-	-	-	-
HMCAFHEB_00549	1.77e-70	-	-	-	-	-	-	-	-
HMCAFHEB_00550	0.0	-	-	-	S	-	-	-	Phage-related minor tail protein
HMCAFHEB_00551	3.17e-190	-	-	-	S	-	-	-	phage tail
HMCAFHEB_00552	0.0	-	-	-	S	-	-	-	Prophage endopeptidase tail
HMCAFHEB_00553	1.72e-84	-	-	-	-	-	-	-	-
HMCAFHEB_00554	2.5e-299	-	-	-	-	-	-	-	-
HMCAFHEB_00555	2.74e-66	-	-	-	MU	-	-	-	outer membrane autotransporter barrel domain protein
HMCAFHEB_00556	2.53e-83	-	-	-	-	-	-	-	-
HMCAFHEB_00557	3.67e-88	-	-	-	S	-	-	-	SPP1 phage holin
HMCAFHEB_00558	1.67e-169	-	-	-	M	-	-	-	NLP P60 protein
HMCAFHEB_00562	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HMCAFHEB_00563	1.36e-207	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HMCAFHEB_00565	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HMCAFHEB_00566	6.65e-235	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HMCAFHEB_00567	1.83e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HMCAFHEB_00568	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HMCAFHEB_00569	3.99e-231	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
HMCAFHEB_00570	3.07e-201	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HMCAFHEB_00571	7.1e-230	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HMCAFHEB_00572	1.75e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMCAFHEB_00573	2.41e-23	-	-	-	K	-	-	-	MerR family regulatory protein
HMCAFHEB_00574	1.88e-249	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HMCAFHEB_00575	6.07e-203	-	-	-	-	-	-	-	-
HMCAFHEB_00576	1.4e-22	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HMCAFHEB_00577	1.36e-19	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HMCAFHEB_00578	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HMCAFHEB_00579	8.03e-311	-	-	-	V	-	-	-	MatE
HMCAFHEB_00580	1.14e-167	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
HMCAFHEB_00581	2.92e-171	-	-	-	L	ko:K07457	-	ko00000	endonuclease III
HMCAFHEB_00582	3.05e-121	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HMCAFHEB_00583	1.13e-226	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HMCAFHEB_00584	1.53e-89	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
HMCAFHEB_00585	1.99e-284	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA N-terminal domain
HMCAFHEB_00586	9.61e-54	-	-	-	K	-	-	-	Helix-turn-helix
HMCAFHEB_00587	3.44e-63	tam	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
HMCAFHEB_00588	7.03e-24	-	-	-	-	-	-	-	-
HMCAFHEB_00589	1.66e-131	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCAFHEB_00590	2.33e-84	-	-	-	T	-	-	-	Domain of unknown function (DUF4234)
HMCAFHEB_00591	1.23e-221	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HMCAFHEB_00592	6.72e-158	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HMCAFHEB_00593	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMCAFHEB_00594	6.15e-185	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HMCAFHEB_00595	8.41e-114	dkg	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
HMCAFHEB_00597	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HMCAFHEB_00598	0.0	-	-	-	K	-	-	-	WYL domain
HMCAFHEB_00599	9.08e-71	-	-	-	-	-	-	-	-
HMCAFHEB_00600	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
HMCAFHEB_00601	1.11e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HMCAFHEB_00602	5.93e-183	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HMCAFHEB_00605	1.49e-117	-	-	-	K	-	-	-	Putative zinc ribbon domain
HMCAFHEB_00606	4.36e-162	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HMCAFHEB_00607	3.04e-124	-	-	-	L	-	-	-	DNA integration
HMCAFHEB_00609	8.13e-82	-	-	-	-	-	-	-	-
HMCAFHEB_00610	1.19e-154	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HMCAFHEB_00611	2.88e-96	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
HMCAFHEB_00612	4.58e-181	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HMCAFHEB_00613	2.78e-57	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
HMCAFHEB_00614	4.59e-222	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HMCAFHEB_00615	3.16e-151	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMCAFHEB_00616	1.07e-200	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
HMCAFHEB_00617	1.2e-54	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
HMCAFHEB_00618	8.92e-144	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
HMCAFHEB_00619	1.12e-246	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMCAFHEB_00620	2.26e-210	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HMCAFHEB_00621	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HMCAFHEB_00622	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HMCAFHEB_00623	9.44e-187	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HMCAFHEB_00624	9.88e-167	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HMCAFHEB_00625	5.17e-56	-	-	-	-	-	-	-	-
HMCAFHEB_00626	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HMCAFHEB_00627	2.72e-314	-	-	-	-	-	-	-	-
HMCAFHEB_00628	4.72e-212	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HMCAFHEB_00629	4.72e-284	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HMCAFHEB_00630	3.9e-131	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HMCAFHEB_00631	3.73e-72	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
HMCAFHEB_00632	6.91e-259	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMCAFHEB_00633	1.83e-135	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMCAFHEB_00634	2.64e-129	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HMCAFHEB_00635	2.79e-176	yebC	-	-	K	-	-	-	transcriptional regulatory protein
HMCAFHEB_00636	0.0	-	3.2.1.52	GH20	M	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HMCAFHEB_00637	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMCAFHEB_00638	0.0	-	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMCAFHEB_00641	0.0	-	-	-	-	-	-	-	-
HMCAFHEB_00645	1.18e-198	-	-	-	S	-	-	-	PAC2 family
HMCAFHEB_00646	8.18e-216	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HMCAFHEB_00647	1.36e-202	-	-	-	G	-	-	-	Fructosamine kinase
HMCAFHEB_00648	5.18e-272	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HMCAFHEB_00649	7.56e-285	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMCAFHEB_00650	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
HMCAFHEB_00651	4.49e-258	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HMCAFHEB_00652	1.88e-183	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HMCAFHEB_00653	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HMCAFHEB_00655	1.22e-307	-	-	-	V	-	-	-	MatE
HMCAFHEB_00656	2.44e-208	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HMCAFHEB_00657	1.18e-225	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HMCAFHEB_00658	1.2e-45	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
HMCAFHEB_00659	3.84e-189	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMCAFHEB_00660	1.35e-283	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
HMCAFHEB_00661	3.23e-222	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HMCAFHEB_00662	4.29e-227	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HMCAFHEB_00663	2.05e-228	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
HMCAFHEB_00664	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMCAFHEB_00665	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HMCAFHEB_00666	1.37e-118	-	-	-	-	-	-	-	-
HMCAFHEB_00667	1.09e-77	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HMCAFHEB_00668	1.23e-150	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HMCAFHEB_00669	6.16e-315	-	2.7.13.3	-	T	ko:K18351	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HMCAFHEB_00670	2.4e-180	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HMCAFHEB_00671	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HMCAFHEB_00672	8.31e-254	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HMCAFHEB_00673	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HMCAFHEB_00674	2.84e-263	-	2.7.1.162	-	S	ko:K13059	-	ko00000,ko01000	Phosphotransferase enzyme family
HMCAFHEB_00675	3.68e-277	-	-	-	GK	-	-	-	ROK family
HMCAFHEB_00676	2.13e-226	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HMCAFHEB_00677	1.54e-301	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
HMCAFHEB_00678	2.63e-166	-	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HMCAFHEB_00679	9.98e-26	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
HMCAFHEB_00680	1.99e-113	-	-	-	Q	-	-	-	Acetyltransferase (GNAT) domain
HMCAFHEB_00681	1.23e-69	-	-	-	S	-	-	-	Putative heavy-metal-binding
HMCAFHEB_00682	1.21e-63	-	-	-	V	-	-	-	ABC transporter permease
HMCAFHEB_00685	3.14e-11	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HMCAFHEB_00686	5.83e-26	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HMCAFHEB_00687	9.82e-215	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
HMCAFHEB_00688	5.68e-141	-	-	-	L	-	-	-	PFAM Integrase catalytic
HMCAFHEB_00689	2.29e-151	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HMCAFHEB_00690	8.83e-144	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HMCAFHEB_00691	9.75e-140	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HMCAFHEB_00693	9.34e-106	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HMCAFHEB_00694	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HMCAFHEB_00695	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HMCAFHEB_00696	4.74e-106	-	-	-	-	-	-	-	-
HMCAFHEB_00697	9.87e-90	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HMCAFHEB_00698	1.03e-24	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HMCAFHEB_00699	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
HMCAFHEB_00700	0.0	-	-	-	S	-	-	-	Glycosyl hydrolases related to GH101 family, GH129
HMCAFHEB_00701	6.85e-255	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
HMCAFHEB_00702	5.54e-171	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCAFHEB_00704	9.86e-267	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HMCAFHEB_00705	3.48e-304	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
HMCAFHEB_00706	2.56e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
HMCAFHEB_00707	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
HMCAFHEB_00708	0.0	dinF	-	-	V	-	-	-	MatE
HMCAFHEB_00709	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HMCAFHEB_00710	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
HMCAFHEB_00711	1.02e-181	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
HMCAFHEB_00712	3.15e-44	-	-	-	S	-	-	-	granule-associated protein
HMCAFHEB_00713	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
HMCAFHEB_00714	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HMCAFHEB_00715	6.68e-57	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
HMCAFHEB_00716	1.45e-297	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
HMCAFHEB_00717	7.09e-164	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMCAFHEB_00718	5.56e-213	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
HMCAFHEB_00719	3.77e-81	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HMCAFHEB_00720	1.12e-78	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HMCAFHEB_00722	3.33e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMCAFHEB_00723	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HMCAFHEB_00724	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMCAFHEB_00725	1.96e-251	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HMCAFHEB_00726	6.51e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
HMCAFHEB_00727	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
HMCAFHEB_00728	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HMCAFHEB_00729	1.44e-297	-	2.6.1.1	-	E	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HMCAFHEB_00730	7.67e-118	lrp_3	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
HMCAFHEB_00731	9.37e-96	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
HMCAFHEB_00732	0.0	-	-	-	S	-	-	-	domain protein
HMCAFHEB_00733	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMCAFHEB_00734	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HMCAFHEB_00735	4.88e-161	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HMCAFHEB_00736	5.57e-175	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
HMCAFHEB_00737	5.6e-170	-	-	-	-	-	-	-	-
HMCAFHEB_00738	1.65e-133	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HMCAFHEB_00740	1.13e-118	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HMCAFHEB_00741	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HMCAFHEB_00742	0.0	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
HMCAFHEB_00743	9.17e-59	-	-	-	-	-	-	-	-
HMCAFHEB_00745	8.97e-110	-	-	-	L	-	-	-	Phage integrase family
HMCAFHEB_00746	1.43e-66	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HMCAFHEB_00747	1.18e-28	-	-	-	S	-	-	-	Bacteriophage holin family
HMCAFHEB_00750	0.0	-	-	-	NT	-	-	-	phage tail tape measure protein
HMCAFHEB_00752	9.9e-59	-	-	-	-	-	-	-	-
HMCAFHEB_00753	2.47e-60	-	-	-	-	-	-	-	-
HMCAFHEB_00754	2.78e-35	-	-	-	-	-	-	-	-
HMCAFHEB_00755	6.02e-52	-	-	-	-	-	-	-	-
HMCAFHEB_00756	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HMCAFHEB_00757	9.1e-248	-	-	-	S	-	-	-	Phage portal protein
HMCAFHEB_00758	0.0	-	-	-	S	-	-	-	Terminase
HMCAFHEB_00759	1.69e-65	-	-	-	-	-	-	-	-
HMCAFHEB_00760	1.05e-165	-	-	-	L	-	-	-	HNH endonuclease
HMCAFHEB_00761	1.39e-54	-	-	-	-	-	-	-	-
HMCAFHEB_00763	1.67e-38	-	-	-	-	-	-	-	-
HMCAFHEB_00767	2.41e-264	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HMCAFHEB_00768	3.54e-188	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HMCAFHEB_00770	1.42e-39	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMCAFHEB_00771	5.05e-96	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMCAFHEB_00772	2.81e-192	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMCAFHEB_00773	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMCAFHEB_00774	2.73e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMCAFHEB_00775	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMCAFHEB_00776	1.39e-66	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HMCAFHEB_00777	5.46e-169	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HMCAFHEB_00778	8.27e-187	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HMCAFHEB_00779	0.0	-	-	-	-	-	-	-	-
HMCAFHEB_00780	4.55e-194	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
HMCAFHEB_00781	2.14e-119	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HMCAFHEB_00782	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HMCAFHEB_00783	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
HMCAFHEB_00784	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
HMCAFHEB_00785	1.13e-127	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HMCAFHEB_00786	4.39e-209	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
HMCAFHEB_00788	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
HMCAFHEB_00789	3.14e-155	-	-	-	-	-	-	-	-
HMCAFHEB_00790	8.32e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HMCAFHEB_00791	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HMCAFHEB_00792	2.19e-56	-	-	-	K	-	-	-	purine nucleotide biosynthetic process
HMCAFHEB_00793	1.52e-122	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HMCAFHEB_00794	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HMCAFHEB_00795	2.45e-91	megL	4.4.1.11	-	E	ko:K01761	ko00270,ko00450,map00270,map00450	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HMCAFHEB_00796	7.28e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMCAFHEB_00797	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMCAFHEB_00798	3.47e-128	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HMCAFHEB_00799	1.26e-55	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HMCAFHEB_00800	6.85e-214	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
HMCAFHEB_00801	1e-45	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HMCAFHEB_00802	2.49e-184	-	-	-	L	-	-	-	Helix-turn-helix domain
HMCAFHEB_00803	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
HMCAFHEB_00804	8.18e-243	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
HMCAFHEB_00805	9.04e-186	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HMCAFHEB_00806	2.23e-164	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HMCAFHEB_00807	9.13e-119	-	-	-	D	-	-	-	nuclear chromosome segregation
HMCAFHEB_00808	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HMCAFHEB_00809	7.76e-236	-	-	-	L	-	-	-	Excalibur calcium-binding domain
HMCAFHEB_00810	1.38e-277	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HMCAFHEB_00811	5.46e-313	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HMCAFHEB_00812	3.71e-133	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HMCAFHEB_00813	3.6e-305	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HMCAFHEB_00814	2.2e-160	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HMCAFHEB_00815	2.59e-311	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HMCAFHEB_00816	1.33e-165	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HMCAFHEB_00817	2.83e-261	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
HMCAFHEB_00818	8.51e-219	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HMCAFHEB_00819	2.21e-232	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HMCAFHEB_00820	1.29e-189	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMCAFHEB_00821	3.01e-218	-	-	-	S	-	-	-	Protein conserved in bacteria
HMCAFHEB_00823	5.92e-313	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HMCAFHEB_00825	0.0	-	-	-	G	-	-	-	BNR repeat-like domain
HMCAFHEB_00826	2.67e-230	xynB2	1.1.1.169	-	E	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	lipolytic protein G-D-S-L family
HMCAFHEB_00827	5.06e-115	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMCAFHEB_00828	5.13e-61	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMCAFHEB_00830	0.0	-	-	-	T	-	-	-	Forkhead associated domain
HMCAFHEB_00831	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
HMCAFHEB_00832	2.87e-56	-	-	-	-	-	-	-	-
HMCAFHEB_00833	2.46e-140	-	-	-	NO	-	-	-	SAF
HMCAFHEB_00834	1.88e-51	-	-	-	S	-	-	-	Putative regulatory protein
HMCAFHEB_00835	3.29e-153	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
HMCAFHEB_00836	6.96e-191	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HMCAFHEB_00837	4.53e-266	-	-	-	-	-	-	-	-
HMCAFHEB_00838	3.49e-63	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMCAFHEB_00839	1.94e-167	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HMCAFHEB_00840	3.23e-57	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HMCAFHEB_00844	2.71e-35	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
HMCAFHEB_00845	2.6e-278	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HMCAFHEB_00846	3.55e-81	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
HMCAFHEB_00847	1.58e-282	dapC	-	-	E	-	-	-	Aminotransferase class I and II
HMCAFHEB_00848	4.45e-305	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMCAFHEB_00850	0.0	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
HMCAFHEB_00851	4e-147	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
HMCAFHEB_00852	5.92e-155	-	-	-	-	-	-	-	-
HMCAFHEB_00853	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HMCAFHEB_00854	2.64e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMCAFHEB_00855	1.71e-99	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HMCAFHEB_00856	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HMCAFHEB_00857	1.83e-299	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HMCAFHEB_00858	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HMCAFHEB_00859	7.89e-213	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HMCAFHEB_00860	8.58e-112	-	-	-	S	-	-	-	YwiC-like protein
HMCAFHEB_00861	6.31e-47	-	-	-	S	-	-	-	YwiC-like protein
HMCAFHEB_00862	1.07e-18	-	-	-	S	-	-	-	YwiC-like protein
HMCAFHEB_00863	5.42e-67	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HMCAFHEB_00864	6.65e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMCAFHEB_00865	1.34e-154	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HMCAFHEB_00866	2.54e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HMCAFHEB_00867	1.15e-196	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMCAFHEB_00868	1.4e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HMCAFHEB_00869	2.21e-74	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HMCAFHEB_00870	2.73e-161	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HMCAFHEB_00871	2.71e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HMCAFHEB_00872	6.77e-51	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HMCAFHEB_00873	9.4e-57	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HMCAFHEB_00874	7.32e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HMCAFHEB_00875	9.32e-70	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HMCAFHEB_00876	1.6e-133	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMCAFHEB_00877	7.06e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMCAFHEB_00878	9.65e-91	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMCAFHEB_00879	2.69e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMCAFHEB_00880	1.53e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMCAFHEB_00881	2.04e-149	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HMCAFHEB_00882	1.46e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
HMCAFHEB_00883	1.51e-94	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HMCAFHEB_00884	9.36e-317	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMCAFHEB_00885	4.79e-129	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HMCAFHEB_00886	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMCAFHEB_00887	1.03e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HMCAFHEB_00888	6.96e-83	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMCAFHEB_00889	7.34e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMCAFHEB_00890	1.4e-236	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMCAFHEB_00891	2.18e-94	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HMCAFHEB_00892	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
HMCAFHEB_00893	4.08e-221	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMCAFHEB_00894	0.0	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
HMCAFHEB_00895	9.14e-198	-	-	-	E	-	-	-	Transglutaminase/protease-like homologues
HMCAFHEB_00897	2.31e-35	-	-	-	-	-	-	-	-
HMCAFHEB_00898	4.63e-34	tnp3503b	-	-	L	-	-	-	Transposase and inactivated derivatives
HMCAFHEB_00899	1.27e-224	-	-	-	-	-	-	-	-
HMCAFHEB_00900	3.31e-241	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HMCAFHEB_00901	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMCAFHEB_00902	8.76e-124	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMCAFHEB_00903	3.18e-299	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMCAFHEB_00904	6.96e-302	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
HMCAFHEB_00905	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HMCAFHEB_00906	6.9e-142	-	-	-	-	-	-	-	-
HMCAFHEB_00907	5.18e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
HMCAFHEB_00908	1.28e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HMCAFHEB_00909	4.34e-261	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMCAFHEB_00910	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
HMCAFHEB_00911	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HMCAFHEB_00912	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HMCAFHEB_00914	4.43e-57	-	-	-	M	-	-	-	Spy0128-like isopeptide containing domain
HMCAFHEB_00915	4.73e-05	-	-	-	O	ko:K18546	-	ko00000,ko01000,ko01002	Peptidase s1 and s6 chymotrypsin hap
HMCAFHEB_00916	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
HMCAFHEB_00917	5.06e-198	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HMCAFHEB_00918	2.27e-270	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HMCAFHEB_00919	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
HMCAFHEB_00920	3.46e-302	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMCAFHEB_00922	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
HMCAFHEB_00924	8e-108	-	-	-	-	-	-	-	-
HMCAFHEB_00925	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HMCAFHEB_00926	7.54e-240	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
HMCAFHEB_00927	5.83e-181	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HMCAFHEB_00928	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HMCAFHEB_00929	1.18e-162	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HMCAFHEB_00930	0.0	tcsS3	-	-	KT	-	-	-	PspC domain
HMCAFHEB_00931	0.0	pspC	-	-	KT	-	-	-	PspC domain
HMCAFHEB_00932	1.6e-203	-	-	-	-	-	-	-	-
HMCAFHEB_00933	9.55e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
HMCAFHEB_00934	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
HMCAFHEB_00935	7.45e-278	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
HMCAFHEB_00937	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HMCAFHEB_00938	2.89e-224	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HMCAFHEB_00939	3.69e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMCAFHEB_00941	9.33e-153	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HMCAFHEB_00942	6.51e-288	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HMCAFHEB_00943	4.6e-53	-	-	-	-	-	-	-	-
HMCAFHEB_00944	1.28e-275	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HMCAFHEB_00945	1.18e-228	-	-	-	S	-	-	-	CHAP domain
HMCAFHEB_00946	5.95e-147	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HMCAFHEB_00947	1.31e-244	-	-	-	T	-	-	-	Universal stress protein family
HMCAFHEB_00948	5.29e-95	-	-	-	O	-	-	-	OsmC-like protein
HMCAFHEB_00949	1.18e-221	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HMCAFHEB_00950	5.46e-165	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
HMCAFHEB_00951	2.34e-124	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
HMCAFHEB_00952	1.27e-249	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HMCAFHEB_00953	1.86e-31	-	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
HMCAFHEB_00954	3.56e-145	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCAFHEB_00955	1.12e-269	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HMCAFHEB_00956	4.37e-289	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HMCAFHEB_00957	2e-09	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HMCAFHEB_00958	4.81e-236	-	-	-	-	-	-	-	-
HMCAFHEB_00959	6.72e-140	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HMCAFHEB_00960	1.37e-228	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
HMCAFHEB_00961	1.64e-138	-	-	-	-	-	-	-	-
HMCAFHEB_00962	5.05e-153	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HMCAFHEB_00963	2.44e-302	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HMCAFHEB_00964	4.31e-232	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HMCAFHEB_00965	1.53e-113	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
HMCAFHEB_00966	0.0	lacZ6	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HMCAFHEB_00967	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HMCAFHEB_00968	4.4e-23	-	-	-	S	ko:K18955	-	ko00000,ko03000	Transcription factor WhiB
HMCAFHEB_00970	8.3e-224	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HMCAFHEB_00971	5.63e-255	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HMCAFHEB_00972	2.03e-110	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
HMCAFHEB_00975	1.48e-271	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
HMCAFHEB_00976	5.42e-227	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HMCAFHEB_00977	0.0	-	-	-	S	-	-	-	AI-2E family transporter
HMCAFHEB_00978	3.97e-295	-	-	-	M	-	-	-	Glycosyl transferase family 21
HMCAFHEB_00979	2.26e-215	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMCAFHEB_00980	0.0	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HMCAFHEB_00981	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
HMCAFHEB_00982	7.03e-269	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMCAFHEB_00983	2.65e-127	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HMCAFHEB_00984	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMCAFHEB_00985	2.05e-130	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
HMCAFHEB_00986	7.56e-209	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HMCAFHEB_00987	0.0	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HMCAFHEB_00988	2.35e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
HMCAFHEB_00989	7.64e-219	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
HMCAFHEB_00990	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
HMCAFHEB_00991	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
HMCAFHEB_00992	8.64e-24	-	-	-	M	-	-	-	domain, Protein
HMCAFHEB_00993	4.24e-225	-	-	-	M	-	-	-	domain, Protein
HMCAFHEB_00994	4.33e-162	-	-	-	-	-	-	-	-
HMCAFHEB_00995	4.32e-148	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HMCAFHEB_00996	9.06e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
HMCAFHEB_00997	7.1e-70	-	-	-	S	-	-	-	DUF218 domain
HMCAFHEB_00999	3.06e-144	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HMCAFHEB_01000	5.09e-202	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HMCAFHEB_01001	1.58e-72	-	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	Major facilitator Superfamily
HMCAFHEB_01002	0.0	-	-	-	S	-	-	-	ATPases associated with a variety of cellular activities
HMCAFHEB_01003	3.68e-229	glkA	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HMCAFHEB_01004	1.54e-100	-	-	-	EGP	-	-	-	Major facilitator superfamily
HMCAFHEB_01005	7.9e-48	-	-	-	C	-	-	-	Aldo/keto reductase family
HMCAFHEB_01006	0.0	-	2.5.1.49	-	H	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
HMCAFHEB_01007	1.27e-271	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HMCAFHEB_01008	1.3e-36	-	-	-	L	-	-	-	Transposase
HMCAFHEB_01010	2.89e-191	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HMCAFHEB_01011	1.87e-182	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HMCAFHEB_01012	2.85e-05	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCAFHEB_01013	1.23e-210	-	-	-	EG	-	-	-	EamA-like transporter family
HMCAFHEB_01014	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
HMCAFHEB_01015	1.68e-190	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HMCAFHEB_01016	1.6e-218	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
HMCAFHEB_01017	1.01e-141	-	-	-	-	-	-	-	-
HMCAFHEB_01018	0.0	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	Mycolic acid cyclopropane synthetase
HMCAFHEB_01019	2e-241	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HMCAFHEB_01020	2.74e-209	-	-	-	G	ko:K05340	-	ko00000,ko02000	Sugar transport protein
HMCAFHEB_01021	4.3e-241	-	-	-	K	ko:K13633	-	ko00000,ko03000	helix_turn_helix, arabinose operon control protein
HMCAFHEB_01023	1.85e-48	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HMCAFHEB_01024	9.17e-244	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMCAFHEB_01025	5.69e-235	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMCAFHEB_01026	3.98e-71	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
HMCAFHEB_01027	7.44e-151	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
HMCAFHEB_01028	7.46e-261	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
HMCAFHEB_01029	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HMCAFHEB_01030	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
HMCAFHEB_01031	5.31e-47	-	-	-	KT	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
HMCAFHEB_01032	1.11e-155	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HMCAFHEB_01033	8.15e-205	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HMCAFHEB_01034	0.0	-	-	-	L	-	-	-	PIF1-like helicase
HMCAFHEB_01037	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HMCAFHEB_01038	5.42e-219	-	-	-	-	-	-	-	-
HMCAFHEB_01039	4.3e-151	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
HMCAFHEB_01040	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
HMCAFHEB_01041	2.65e-194	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HMCAFHEB_01042	6.17e-192	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HMCAFHEB_01043	0.0	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
HMCAFHEB_01044	2.92e-131	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
HMCAFHEB_01045	7.05e-248	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
HMCAFHEB_01046	9.91e-72	-	-	-	K	-	-	-	MerR, DNA binding
HMCAFHEB_01047	0.0	-	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HMCAFHEB_01048	4.11e-135	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMCAFHEB_01049	5.53e-285	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HMCAFHEB_01050	0.0	nox	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HMCAFHEB_01051	1.39e-296	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HMCAFHEB_01052	1.49e-309	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HMCAFHEB_01053	1.45e-177	hflK	-	-	O	-	-	-	prohibitin homologues
HMCAFHEB_01054	0.0	aldH	1.2.1.3, 1.2.99.10	-	C	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase family
HMCAFHEB_01055	4.8e-73	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HMCAFHEB_01056	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMCAFHEB_01058	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HMCAFHEB_01059	1.33e-25	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HMCAFHEB_01060	2.17e-243	-	-	-	K	-	-	-	Periplasmic binding protein domain
HMCAFHEB_01061	4.4e-162	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
HMCAFHEB_01062	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HMCAFHEB_01063	3.29e-82	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	carbohydrate transport
HMCAFHEB_01064	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HMCAFHEB_01065	2.65e-184	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HMCAFHEB_01066	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HMCAFHEB_01067	1.41e-217	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMCAFHEB_01068	5.04e-207	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMCAFHEB_01069	1.38e-183	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
HMCAFHEB_01070	3.69e-198	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMCAFHEB_01071	2.53e-240	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMCAFHEB_01072	2.1e-46	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HMCAFHEB_01074	1.02e-97	-	-	-	QT	-	-	-	Purine catabolism regulatory protein-like family
HMCAFHEB_01075	7.55e-50	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMCAFHEB_01078	1.79e-210	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
HMCAFHEB_01079	4.92e-87	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
HMCAFHEB_01080	3.96e-24	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	carboxylic acid catabolic process
HMCAFHEB_01081	4.87e-236	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
HMCAFHEB_01083	4.54e-151	-	-	-	S	-	-	-	CYTH
HMCAFHEB_01084	9.07e-212	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
HMCAFHEB_01085	1.19e-231	-	-	-	-	-	-	-	-
HMCAFHEB_01086	1.4e-240	-	-	-	-	-	-	-	-
HMCAFHEB_01087	1.26e-222	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
HMCAFHEB_01088	1.23e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMCAFHEB_01089	1.43e-95	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMCAFHEB_01090	5.12e-183	-	-	-	-	-	-	-	-
HMCAFHEB_01091	1.69e-169	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCAFHEB_01092	1.49e-292	-	-	-	G	-	-	-	Transmembrane secretion effector
HMCAFHEB_01093	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMCAFHEB_01094	3.04e-280	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
HMCAFHEB_01095	3.36e-249	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HMCAFHEB_01097	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
HMCAFHEB_01098	3.31e-171	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HMCAFHEB_01099	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HMCAFHEB_01100	1.59e-179	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
HMCAFHEB_01101	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HMCAFHEB_01104	1.67e-86	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HMCAFHEB_01105	3.43e-128	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HMCAFHEB_01106	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMCAFHEB_01108	1.84e-156	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HMCAFHEB_01109	5.05e-258	-	-	-	P	-	-	-	NMT1/THI5 like
HMCAFHEB_01110	4.99e-179	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
HMCAFHEB_01111	1.26e-195	-	-	-	-	-	-	-	-
HMCAFHEB_01112	9.49e-163	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HMCAFHEB_01113	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HMCAFHEB_01114	8.73e-127	-	-	-	S	-	-	-	GtrA-like protein
HMCAFHEB_01115	9.48e-83	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
HMCAFHEB_01116	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
HMCAFHEB_01117	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
HMCAFHEB_01118	3.03e-139	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HMCAFHEB_01119	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
HMCAFHEB_01120	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HMCAFHEB_01121	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HMCAFHEB_01122	7.47e-123	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HMCAFHEB_01123	1.14e-57	-	-	-	S	-	-	-	Protein of unknown function (DUF1778)
HMCAFHEB_01124	1.81e-243	-	-	-	C	-	-	-	Aldo/keto reductase family
HMCAFHEB_01125	1.52e-126	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 30 family
HMCAFHEB_01127	4.07e-06	-	-	-	L	-	-	-	Helix-turn-helix domain
HMCAFHEB_01128	7.61e-86	istB	-	-	L	-	-	-	IstB-like ATP binding protein
HMCAFHEB_01129	3.76e-68	istB	-	-	L	-	-	-	IstB-like ATP binding protein
HMCAFHEB_01130	3.52e-251	-	-	-	L	-	-	-	PFAM Integrase catalytic
HMCAFHEB_01131	1.12e-21	-	-	-	L	-	-	-	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HMCAFHEB_01132	0.0	-	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HMCAFHEB_01133	5.46e-189	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMCAFHEB_01134	4.48e-52	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMCAFHEB_01135	6.07e-29	-	-	-	L	-	-	-	Transposase, Mutator family
HMCAFHEB_01136	3.18e-106	-	-	-	-	-	-	-	-
HMCAFHEB_01137	6.4e-123	-	-	-	L	-	-	-	Restriction endonuclease NotI
HMCAFHEB_01139	1.55e-62	-	-	-	-	-	-	-	-
HMCAFHEB_01140	2.02e-191	-	-	-	S	ko:K07058	-	ko00000	Virulence factor BrkB
HMCAFHEB_01141	8.29e-129	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
HMCAFHEB_01142	9.3e-53	urtE	-	-	E	ko:K11963	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMCAFHEB_01143	5.48e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HMCAFHEB_01144	2.21e-109	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMCAFHEB_01145	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HMCAFHEB_01146	4.31e-166	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HMCAFHEB_01147	2.46e-132	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HMCAFHEB_01148	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
HMCAFHEB_01149	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HMCAFHEB_01150	4.01e-235	-	-	-	S	-	-	-	Protein of unknown function (DUF559)
HMCAFHEB_01151	5.06e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HMCAFHEB_01152	6.15e-261	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HMCAFHEB_01153	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HMCAFHEB_01154	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
HMCAFHEB_01155	1.61e-101	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
HMCAFHEB_01156	2.8e-256	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HMCAFHEB_01157	3.1e-80	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMCAFHEB_01158	5.91e-209	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMCAFHEB_01159	1.94e-316	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMCAFHEB_01160	2.17e-253	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HMCAFHEB_01161	0.0	-	3.2.1.8, 3.5.1.104	-	G	ko:K01181,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HMCAFHEB_01162	1.42e-74	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HMCAFHEB_01164	7.82e-65	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HMCAFHEB_01165	4.81e-84	-	-	-	-	-	-	-	-
HMCAFHEB_01166	4.37e-80	-	-	-	-	-	-	-	-
HMCAFHEB_01167	1.68e-176	-	-	-	S	-	-	-	Domain of unknown function (DUF4417)
HMCAFHEB_01168	3.03e-56	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
HMCAFHEB_01169	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HMCAFHEB_01171	1.18e-223	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HMCAFHEB_01172	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
HMCAFHEB_01173	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HMCAFHEB_01174	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
HMCAFHEB_01175	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HMCAFHEB_01177	2.72e-111	-	-	-	Q	-	-	-	Acetyltransferase (GNAT) domain
HMCAFHEB_01178	2.16e-199	-	-	-	I	-	-	-	Serine aminopeptidase, S33
HMCAFHEB_01179	2.48e-69	-	-	-	S	-	-	-	Putative heavy-metal-binding
HMCAFHEB_01180	4.55e-60	-	-	-	D	-	-	-	DivIVA domain protein
HMCAFHEB_01181	1.11e-117	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HMCAFHEB_01182	0.0	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
HMCAFHEB_01184	9.65e-250	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMCAFHEB_01186	1.92e-146	-	-	-	-	-	-	-	-
HMCAFHEB_01187	9.28e-216	-	-	-	EG	-	-	-	EamA-like transporter family
HMCAFHEB_01188	2.14e-261	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
HMCAFHEB_01189	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HMCAFHEB_01190	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HMCAFHEB_01191	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
HMCAFHEB_01192	3.69e-167	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
HMCAFHEB_01193	1.44e-122	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
HMCAFHEB_01194	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
HMCAFHEB_01195	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HMCAFHEB_01196	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HMCAFHEB_01197	5.69e-234	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HMCAFHEB_01198	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HMCAFHEB_01199	9.5e-156	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
HMCAFHEB_01200	5.65e-296	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HMCAFHEB_01201	2.05e-183	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HMCAFHEB_01202	8.05e-100	crgA	-	-	D	-	-	-	Involved in cell division
HMCAFHEB_01203	0.0	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
HMCAFHEB_01204	4.08e-289	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HMCAFHEB_01205	2.64e-245	-	-	-	L	-	-	-	Phage integrase family
HMCAFHEB_01206	6.38e-259	-	-	-	L	ko:K03733	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HMCAFHEB_01207	6.34e-21	-	-	-	L	-	-	-	HTH-like domain
HMCAFHEB_01208	1.97e-185	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
HMCAFHEB_01209	3.13e-46	-	-	-	-	-	-	-	-
HMCAFHEB_01210	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HMCAFHEB_01211	2.26e-95	-	-	-	I	-	-	-	Sterol carrier protein
HMCAFHEB_01212	1.49e-51	-	-	-	V	ko:K06147	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
HMCAFHEB_01213	3.5e-57	-	-	-	L	ko:K07485	-	ko00000	Transposase
HMCAFHEB_01214	6.48e-14	istB	-	-	L	-	-	-	IstB-like ATP binding protein
HMCAFHEB_01215	7.04e-57	-	-	-	L	-	-	-	Integrase core domain
HMCAFHEB_01216	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
HMCAFHEB_01217	1.9e-17	-	-	-	-	-	-	-	-
HMCAFHEB_01218	5.84e-22	yccF	-	-	S	-	-	-	Inner membrane component domain
HMCAFHEB_01219	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HMCAFHEB_01220	1.69e-206	tnp3521a2	-	-	L	-	-	-	Integrase core domain
HMCAFHEB_01221	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
HMCAFHEB_01222	1.17e-133	-	-	-	-	-	-	-	-
HMCAFHEB_01226	8.92e-141	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HMCAFHEB_01227	1.59e-91	-	-	GT2	S	ko:K12992	ko02025,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyltransferase like family 2
HMCAFHEB_01228	2.39e-136	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	transferase activity, transferring glycosyl groups
HMCAFHEB_01229	6.18e-110	-	-	-	M	-	-	-	Polysaccharide pyruvyl transferase
HMCAFHEB_01230	1.96e-132	rgpD	3.6.3.40	-	P	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HMCAFHEB_01231	6.84e-96	rgpC	-	-	GM	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HMCAFHEB_01232	1.4e-203	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HMCAFHEB_01233	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HMCAFHEB_01234	1.01e-254	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HMCAFHEB_01235	1.17e-88	-	-	-	L	-	-	-	Winged helix-turn helix
HMCAFHEB_01236	1.3e-110	istB	-	-	L	-	-	-	IstB-like ATP binding protein
HMCAFHEB_01237	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
HMCAFHEB_01238	4e-21	-	-	-	L	-	-	-	Winged helix-turn helix
HMCAFHEB_01240	1.47e-146	dam	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
HMCAFHEB_01241	4.54e-170	-	-	-	-	-	-	-	-
HMCAFHEB_01243	7.07e-61	-	-	-	D	-	-	-	MobA MobL family protein
HMCAFHEB_01244	2.98e-12	-	-	-	L	-	-	-	Transposase
HMCAFHEB_01245	6.68e-231	-	-	-	L	-	-	-	Transposase
HMCAFHEB_01247	2.43e-162	-	-	-	L	-	-	-	IstB-like ATP binding protein
HMCAFHEB_01248	2.7e-27	-	-	-	-	-	-	-	-
HMCAFHEB_01249	1.5e-297	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
HMCAFHEB_01250	4.79e-271	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HMCAFHEB_01251	9.89e-40	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HMCAFHEB_01252	1.19e-258	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HMCAFHEB_01253	2.58e-103	-	-	-	T	-	-	-	protein histidine kinase activity
HMCAFHEB_01254	2.72e-113	-	-	-	K	-	-	-	LytTr DNA-binding domain
HMCAFHEB_01255	5.42e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
HMCAFHEB_01256	1.2e-261	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HMCAFHEB_01257	4.09e-249	-	-	-	S	-	-	-	Protein conserved in bacteria
HMCAFHEB_01258	3.05e-66	-	-	-	S	-	-	-	Amidohydrolase family
HMCAFHEB_01259	2.06e-196	-	-	-	S	-	-	-	Amidohydrolase family
HMCAFHEB_01260	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HMCAFHEB_01261	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HMCAFHEB_01262	4.59e-307	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HMCAFHEB_01263	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HMCAFHEB_01264	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HMCAFHEB_01265	1.01e-137	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
HMCAFHEB_01266	6.08e-154	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HMCAFHEB_01267	1.14e-122	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HMCAFHEB_01268	6.78e-306	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HMCAFHEB_01269	1.15e-239	-	-	-	EG	-	-	-	EamA-like transporter family
HMCAFHEB_01270	2.68e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HMCAFHEB_01271	1.2e-174	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
HMCAFHEB_01272	0.0	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HMCAFHEB_01273	1.49e-54	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMCAFHEB_01274	6.23e-102	ulaC	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMCAFHEB_01275	8.49e-243	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HMCAFHEB_01276	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
HMCAFHEB_01279	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	arabinose metabolic process
HMCAFHEB_01280	9.15e-79	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HMCAFHEB_01281	1.02e-125	gntR	-	-	K	-	-	-	FCD
HMCAFHEB_01282	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HMCAFHEB_01283	1.52e-07	-	-	-	M	-	-	-	PA domain
HMCAFHEB_01284	2.82e-236	-	-	-	L	-	-	-	Phage integrase family
HMCAFHEB_01286	1.49e-290	-	-	-	-	-	-	-	-
HMCAFHEB_01287	7.78e-235	-	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	BsuBI/PstI restriction endonuclease C-terminus
HMCAFHEB_01288	0.0	-	2.1.1.72	-	L	ko:K07317	-	ko00000,ko01000,ko02048	Eco57I restriction-modification methylase
HMCAFHEB_01289	7.91e-140	-	-	-	L	-	-	-	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HMCAFHEB_01290	2.87e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF2442)
HMCAFHEB_01291	9.05e-12	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HMCAFHEB_01292	7.56e-290	-	-	-	I	-	-	-	Serine aminopeptidase, S33
HMCAFHEB_01293	3.79e-239	-	-	-	K	-	-	-	Periplasmic binding protein domain
HMCAFHEB_01294	1.3e-238	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HMCAFHEB_01296	2.04e-104	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
HMCAFHEB_01297	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMCAFHEB_01298	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMCAFHEB_01299	4.38e-119	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
HMCAFHEB_01300	1.32e-306	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMCAFHEB_01301	1.15e-259	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HMCAFHEB_01302	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMCAFHEB_01303	3.88e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HMCAFHEB_01304	2.11e-227	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
HMCAFHEB_01305	8.38e-120	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
HMCAFHEB_01306	6.35e-163	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HMCAFHEB_01307	1.5e-229	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HMCAFHEB_01308	4.65e-311	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HMCAFHEB_01309	1.37e-258	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HMCAFHEB_01310	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
HMCAFHEB_01311	0.0	-	-	-	M	-	-	-	Conserved repeat domain
HMCAFHEB_01312	3.18e-160	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
HMCAFHEB_01313	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
HMCAFHEB_01314	2.83e-145	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
HMCAFHEB_01315	8.91e-212	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HMCAFHEB_01316	8.92e-218	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HMCAFHEB_01317	4.51e-275	rpfB	-	-	S	ko:K21688	-	ko00000	G5
HMCAFHEB_01319	3.02e-200	-	-	-	O	-	-	-	Thioredoxin
HMCAFHEB_01320	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HMCAFHEB_01321	1.32e-221	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HMCAFHEB_01322	2.18e-269	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HMCAFHEB_01323	2.69e-133	-	-	-	L	-	-	-	Helix-turn-helix domain
HMCAFHEB_01324	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
HMCAFHEB_01325	1.41e-308	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HMCAFHEB_01326	1.05e-229	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HMCAFHEB_01327	1.57e-199	-	-	-	-	-	-	-	-
HMCAFHEB_01328	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
HMCAFHEB_01329	2.19e-223	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMCAFHEB_01331	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HMCAFHEB_01332	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
HMCAFHEB_01333	6.04e-144	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
HMCAFHEB_01334	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
HMCAFHEB_01335	6.62e-185	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HMCAFHEB_01336	1.12e-109	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMCAFHEB_01337	5.39e-296	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HMCAFHEB_01338	2.41e-185	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
HMCAFHEB_01339	1.93e-215	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
HMCAFHEB_01340	3.93e-223	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMCAFHEB_01341	3.15e-313	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HMCAFHEB_01342	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HMCAFHEB_01343	6.57e-97	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HMCAFHEB_01344	1.82e-179	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HMCAFHEB_01345	1.04e-289	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HMCAFHEB_01346	1.27e-226	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
HMCAFHEB_01347	7.62e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMCAFHEB_01348	6.31e-171	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HMCAFHEB_01349	1.1e-164	-	-	-	S	-	-	-	alpha beta
HMCAFHEB_01350	4.78e-188	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMCAFHEB_01351	3.07e-188	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HMCAFHEB_01352	4.26e-113	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMCAFHEB_01353	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
HMCAFHEB_01354	5.1e-118	-	-	-	-	-	-	-	-
HMCAFHEB_01355	1.59e-255	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
HMCAFHEB_01356	1.35e-306	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
HMCAFHEB_01357	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
HMCAFHEB_01358	0.0	fadD1	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HMCAFHEB_01359	2.69e-166	-	-	-	M	-	-	-	Peptidase family M23
HMCAFHEB_01361	6.55e-250	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMCAFHEB_01362	4.23e-135	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
HMCAFHEB_01363	1.15e-202	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
HMCAFHEB_01364	3.13e-153	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
HMCAFHEB_01365	3.02e-231	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HMCAFHEB_01366	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
HMCAFHEB_01367	1.08e-160	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
HMCAFHEB_01368	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HMCAFHEB_01369	3.21e-215	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HMCAFHEB_01370	1.72e-218	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HMCAFHEB_01371	4.05e-207	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HMCAFHEB_01372	0.0	-	-	-	E	-	-	-	Serine carboxypeptidase
HMCAFHEB_01373	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HMCAFHEB_01374	8.61e-178	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
HMCAFHEB_01375	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HMCAFHEB_01376	8.85e-209	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HMCAFHEB_01377	8.22e-85	-	-	-	K	-	-	-	Protein of unknown function, DUF488
HMCAFHEB_01378	1.81e-155	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HMCAFHEB_01379	1.12e-126	-	-	-	K	-	-	-	FR47-like protein
HMCAFHEB_01380	1.9e-74	-	-	-	K	-	-	-	Transcriptional regulator
HMCAFHEB_01381	4.42e-46	-	-	-	F	-	-	-	Hydrolase of X-linked nucleoside diphosphate N terminal
HMCAFHEB_01382	2.5e-49	-	-	-	J	-	-	-	Aminoacyl-tRNA editing domain
HMCAFHEB_01383	4.18e-237	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HMCAFHEB_01384	3.59e-25	-	-	-	L	-	-	-	PFAM Integrase catalytic
HMCAFHEB_01385	1.4e-170	-	-	-	S	-	-	-	SOS response associated peptidase (SRAP)
HMCAFHEB_01386	2.48e-160	-	-	-	-	-	-	-	-
HMCAFHEB_01387	1.31e-103	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMCAFHEB_01388	6.84e-227	-	-	-	M	-	-	-	heme binding
HMCAFHEB_01389	6.81e-158	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HMCAFHEB_01391	2.16e-204	-	-	-	-	-	-	-	-
HMCAFHEB_01392	1.68e-116	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HMCAFHEB_01393	1.72e-142	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HMCAFHEB_01394	1.12e-246	-	-	-	V	-	-	-	VanZ like family
HMCAFHEB_01395	6.33e-188	-	-	-	KT	-	-	-	RESPONSE REGULATOR receiver
HMCAFHEB_01396	5.55e-91	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
HMCAFHEB_01397	3.18e-188	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
HMCAFHEB_01398	6.92e-171	-	-	-	C	-	-	-	Putative TM nitroreductase
HMCAFHEB_01399	5.43e-164	-	-	-	-	-	-	-	-
HMCAFHEB_01401	0.0	treS_1	-	-	G	-	-	-	Alpha amylase, catalytic domain
HMCAFHEB_01402	1.08e-101	-	-	-	S	-	-	-	Bacterial PH domain
HMCAFHEB_01403	2.85e-178	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HMCAFHEB_01404	6.1e-89	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMCAFHEB_01405	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMCAFHEB_01407	6.24e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMCAFHEB_01408	5.93e-187	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMCAFHEB_01409	4.42e-121	-	-	-	-	-	-	-	-
HMCAFHEB_01410	2.06e-299	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HMCAFHEB_01411	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
HMCAFHEB_01412	3.24e-158	-	-	-	S	-	-	-	ABC-2 family transporter protein
HMCAFHEB_01413	6.5e-163	-	-	-	S	-	-	-	ABC-2 family transporter protein
HMCAFHEB_01414	2.58e-226	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMCAFHEB_01415	4.04e-77	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HMCAFHEB_01416	1.45e-157	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HMCAFHEB_01417	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HMCAFHEB_01418	3.15e-235	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMCAFHEB_01419	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
HMCAFHEB_01420	5.24e-150	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
HMCAFHEB_01421	7.25e-140	-	-	-	-	-	-	-	-
HMCAFHEB_01422	3.26e-175	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HMCAFHEB_01424	1.25e-241	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
HMCAFHEB_01425	2.48e-276	-	-	-	L	-	-	-	Tetratricopeptide repeat
HMCAFHEB_01426	0.0	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMCAFHEB_01427	2.91e-184	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HMCAFHEB_01428	9.62e-142	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HMCAFHEB_01429	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HMCAFHEB_01430	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HMCAFHEB_01431	0.0	-	-	-	K	-	-	-	Putative DNA-binding domain
HMCAFHEB_01432	1.33e-112	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HMCAFHEB_01433	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	modification (methylase) protein of type I restriction-modification system K03427
HMCAFHEB_01434	2.59e-198	-	-	-	S	-	-	-	Domain of unknown function (DUF4357)
HMCAFHEB_01435	3.26e-57	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
HMCAFHEB_01436	2.49e-228	-	-	-	L	-	-	-	Phage integrase family
HMCAFHEB_01437	5.96e-304	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HMCAFHEB_01438	1.29e-112	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HMCAFHEB_01439	2.51e-234	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMCAFHEB_01440	1.69e-314	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HMCAFHEB_01441	4.12e-227	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HMCAFHEB_01442	3.67e-275	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HMCAFHEB_01443	4.51e-261	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HMCAFHEB_01444	1.23e-133	-	-	-	-	-	-	-	-
HMCAFHEB_01445	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
HMCAFHEB_01446	1.51e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HMCAFHEB_01447	3.81e-200	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMCAFHEB_01448	1.43e-174	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMCAFHEB_01449	2.18e-174	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HMCAFHEB_01450	1.03e-70	-	-	-	IQ	-	-	-	oxidoreductase activity
HMCAFHEB_01452	2.73e-111	-	-	-	K	-	-	-	AraC-like ligand binding domain
HMCAFHEB_01453	9.59e-305	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
HMCAFHEB_01454	1.72e-204	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HMCAFHEB_01455	2.75e-239	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HMCAFHEB_01456	2.12e-185	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HMCAFHEB_01457	3.18e-153	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
HMCAFHEB_01458	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HMCAFHEB_01460	0.0	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
HMCAFHEB_01461	4.5e-162	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HMCAFHEB_01462	1.5e-96	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HMCAFHEB_01463	1.59e-48	-	-	-	-	-	-	-	-
HMCAFHEB_01464	1.66e-46	-	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
HMCAFHEB_01465	3.35e-84	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HMCAFHEB_01466	1.1e-112	-	-	-	S	-	-	-	Helix-turn-helix
HMCAFHEB_01467	1.34e-264	-	-	-	S	-	-	-	Short C-terminal domain
HMCAFHEB_01468	1.1e-30	-	-	-	-	-	-	-	-
HMCAFHEB_01470	6.04e-103	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HMCAFHEB_01471	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HMCAFHEB_01472	4.24e-108	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HMCAFHEB_01473	1.1e-201	-	-	-	J	-	-	-	Methyltransferase domain
HMCAFHEB_01474	5.59e-78	yccF	-	-	S	-	-	-	Inner membrane component domain
HMCAFHEB_01475	2.24e-161	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
HMCAFHEB_01476	1.1e-311	-	-	-	K	-	-	-	Fic/DOC family
HMCAFHEB_01477	8.37e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMCAFHEB_01478	1.73e-290	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K10907,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HMCAFHEB_01479	9.77e-123	-	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMCAFHEB_01480	2.33e-262	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMCAFHEB_01481	1.63e-237	acoB	1.2.4.1, 1.2.4.4	-	C	ko:K00162,ko:K11381,ko:K21417	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
HMCAFHEB_01482	2.43e-240	acoA	1.2.4.1	-	C	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HMCAFHEB_01483	1.1e-188	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
HMCAFHEB_01484	2.08e-213	iaaA	3.4.19.5	-	E	ko:K13051	-	ko00000,ko01000,ko01002	Asparaginase
HMCAFHEB_01485	2.58e-184	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMCAFHEB_01486	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
HMCAFHEB_01487	0.0	-	-	-	T	-	-	-	Histidine kinase
HMCAFHEB_01488	2.92e-171	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HMCAFHEB_01489	0.0	-	-	-	I	-	-	-	PAP2 superfamily
HMCAFHEB_01490	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HMCAFHEB_01491	8.48e-215	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCAFHEB_01492	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
HMCAFHEB_01493	9.86e-202	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HMCAFHEB_01494	3.62e-212	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HMCAFHEB_01495	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
HMCAFHEB_01496	1.52e-75	-	-	-	L	ko:K07443	-	ko00000	6-O-methylguanine DNA methyltransferase, DNA binding domain
HMCAFHEB_01497	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
HMCAFHEB_01498	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
HMCAFHEB_01499	2.23e-93	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
HMCAFHEB_01500	2.51e-235	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HMCAFHEB_01501	3.52e-151	safC	-	-	S	-	-	-	O-methyltransferase
HMCAFHEB_01502	4.26e-222	fmt2	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HMCAFHEB_01503	8.28e-291	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HMCAFHEB_01504	1.28e-298	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
HMCAFHEB_01507	5.01e-311	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMCAFHEB_01508	6.56e-164	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMCAFHEB_01509	4.05e-147	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMCAFHEB_01510	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HMCAFHEB_01511	9.36e-310	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMCAFHEB_01512	0.0	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
HMCAFHEB_01513	1.94e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
HMCAFHEB_01514	3.65e-222	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMCAFHEB_01515	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HMCAFHEB_01516	3.51e-52	-	-	-	-	-	-	-	-
HMCAFHEB_01517	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HMCAFHEB_01518	6.96e-286	-	-	-	S	-	-	-	Peptidase dimerisation domain
HMCAFHEB_01519	1.49e-121	-	-	-	P	-	-	-	ABC-type metal ion transport system permease component
HMCAFHEB_01520	2.76e-212	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HMCAFHEB_01521	3.42e-134	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMCAFHEB_01522	2.96e-265	-	-	-	E	-	-	-	Belongs to the peptidase S1B family
HMCAFHEB_01524	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMCAFHEB_01525	1.42e-110	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HMCAFHEB_01526	2.45e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
HMCAFHEB_01527	6.71e-241	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
HMCAFHEB_01528	3.3e-300	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HMCAFHEB_01529	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
HMCAFHEB_01530	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
HMCAFHEB_01531	1.65e-34	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HMCAFHEB_01532	4.54e-63	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
HMCAFHEB_01533	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HMCAFHEB_01534	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
HMCAFHEB_01535	1.99e-250	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMCAFHEB_01536	2.41e-158	-	-	-	-	-	-	-	-
HMCAFHEB_01537	7.75e-258	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HMCAFHEB_01538	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
HMCAFHEB_01539	2.06e-171	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HMCAFHEB_01540	7.57e-141	-	-	-	-	-	-	-	-
HMCAFHEB_01541	4.2e-242	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HMCAFHEB_01542	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMCAFHEB_01543	3.68e-152	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HMCAFHEB_01546	1.2e-113	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HMCAFHEB_01547	7.71e-276	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMCAFHEB_01548	3.38e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
HMCAFHEB_01549	1.03e-105	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HMCAFHEB_01550	1.14e-124	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HMCAFHEB_01551	9.72e-157	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMCAFHEB_01552	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
HMCAFHEB_01553	2.11e-175	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HMCAFHEB_01554	1.04e-235	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMCAFHEB_01555	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HMCAFHEB_01556	1.42e-156	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
HMCAFHEB_01557	8.68e-216	-	-	-	EG	-	-	-	EamA-like transporter family
HMCAFHEB_01558	8.71e-176	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HMCAFHEB_01559	3.09e-151	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
HMCAFHEB_01560	0.0	-	-	-	T	-	-	-	Histidine kinase
HMCAFHEB_01561	6.09e-152	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HMCAFHEB_01562	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
HMCAFHEB_01563	0.0	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HMCAFHEB_01564	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HMCAFHEB_01565	6.94e-304	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HMCAFHEB_01566	1.18e-149	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMCAFHEB_01567	3.8e-135	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMCAFHEB_01569	1.38e-250	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HMCAFHEB_01570	7.01e-182	-	-	-	S	-	-	-	Esterase-like activity of phytase
HMCAFHEB_01571	1.22e-217	-	-	-	S	-	-	-	Esterase-like activity of phytase
HMCAFHEB_01572	5.83e-293	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMCAFHEB_01573	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMCAFHEB_01574	9.4e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HMCAFHEB_01575	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HMCAFHEB_01577	3.66e-253	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
HMCAFHEB_01578	7.32e-290	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
HMCAFHEB_01579	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
HMCAFHEB_01580	1.83e-296	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HMCAFHEB_01581	2.05e-177	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HMCAFHEB_01582	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
HMCAFHEB_01583	5.92e-142	-	-	-	-	-	-	-	-
HMCAFHEB_01584	2.2e-140	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
HMCAFHEB_01585	3.04e-132	nnrE	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
HMCAFHEB_01586	4.61e-38	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HMCAFHEB_01587	1.64e-90	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMCAFHEB_01588	9.82e-45	-	-	-	-	-	-	-	-
HMCAFHEB_01589	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
HMCAFHEB_01590	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HMCAFHEB_01591	1.21e-244	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HMCAFHEB_01592	5.35e-307	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HMCAFHEB_01593	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HMCAFHEB_01594	0.0	-	-	-	S	-	-	-	Putative esterase
HMCAFHEB_01595	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
HMCAFHEB_01597	1.85e-210	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HMCAFHEB_01598	2.69e-180	-	-	-	S	-	-	-	cobalamin synthesis protein
HMCAFHEB_01599	6.47e-64	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
HMCAFHEB_01600	4.85e-65	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMCAFHEB_01601	7.57e-57	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HMCAFHEB_01602	3.05e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
HMCAFHEB_01603	1.07e-32	-	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal L32p protein family
HMCAFHEB_01604	2.14e-259	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
HMCAFHEB_01605	3.19e-198	-	-	-	S	-	-	-	TIGRFAM TIGR03943 family protein
HMCAFHEB_01606	1.53e-60	-	-	-	-	-	-	-	-
HMCAFHEB_01607	2.66e-96	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HMCAFHEB_01608	6e-290	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HMCAFHEB_01609	5.14e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HMCAFHEB_01610	5.85e-228	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
HMCAFHEB_01611	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HMCAFHEB_01613	2.12e-59	-	-	-	S	ko:K06990	-	ko00000,ko04812	Memo-like protein
HMCAFHEB_01614	4.27e-293	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HMCAFHEB_01615	2.73e-206	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HMCAFHEB_01616	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HMCAFHEB_01617	1.69e-311	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
HMCAFHEB_01618	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMCAFHEB_01619	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
HMCAFHEB_01620	2.63e-121	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HMCAFHEB_01622	1.27e-118	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HMCAFHEB_01623	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HMCAFHEB_01624	1.4e-282	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HMCAFHEB_01625	1.83e-244	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HMCAFHEB_01626	1.03e-141	-	-	-	-	-	-	-	-
HMCAFHEB_01627	5.6e-205	-	-	-	L	ko:K07493	-	ko00000	PFAM Transposase, Mutator family
HMCAFHEB_01628	1.31e-44	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
HMCAFHEB_01629	1.74e-75	-	-	-	S	-	-	-	pathogenesis
HMCAFHEB_01630	6.03e-86	-	-	-	-	-	-	-	-
HMCAFHEB_01633	1.71e-116	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
HMCAFHEB_01635	1.13e-108	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HMCAFHEB_01636	1.65e-72	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HMCAFHEB_01637	1.56e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF4127)
HMCAFHEB_01638	2.14e-119	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMCAFHEB_01639	2.78e-177	rfbP	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HMCAFHEB_01640	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
HMCAFHEB_01641	5.91e-297	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HMCAFHEB_01642	8.53e-158	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
HMCAFHEB_01643	1.22e-216	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
HMCAFHEB_01645	2.28e-258	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HMCAFHEB_01646	1.55e-134	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HMCAFHEB_01647	7.6e-217	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HMCAFHEB_01650	9.49e-143	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HMCAFHEB_01651	8.26e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HMCAFHEB_01652	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HMCAFHEB_01654	6.53e-259	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HMCAFHEB_01655	6.64e-170	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMCAFHEB_01656	4.9e-200	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HMCAFHEB_01657	2.33e-81	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMCAFHEB_01658	8.39e-167	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Class II Aldolase and Adducin N-terminal domain
HMCAFHEB_01659	6.29e-220	-	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
HMCAFHEB_01660	0.0	-	2.7.1.53	-	G	ko:K00880	ko00040,ko00053,map00040,map00053	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HMCAFHEB_01661	1.46e-283	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HMCAFHEB_01662	2.46e-221	-	-	-	K	-	-	-	Putative sugar-binding domain
HMCAFHEB_01663	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMCAFHEB_01664	0.0	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMCAFHEB_01665	1e-28	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	Cation transporting ATPase, C-terminus
HMCAFHEB_01666	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	Cation transporting ATPase, C-terminus
HMCAFHEB_01667	4.87e-155	mgtC	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HMCAFHEB_01669	4.71e-224	-	-	-	-	-	-	-	-
HMCAFHEB_01670	3.25e-24	-	-	-	-	-	-	-	-
HMCAFHEB_01672	2.09e-272	-	-	-	-	-	-	-	-
HMCAFHEB_01673	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HMCAFHEB_01676	2.19e-225	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
HMCAFHEB_01677	9.76e-153	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMCAFHEB_01678	6.69e-173	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HMCAFHEB_01679	2.46e-315	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMCAFHEB_01681	1.26e-118	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HMCAFHEB_01682	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
HMCAFHEB_01683	1.56e-179	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMCAFHEB_01684	2.72e-34	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HMCAFHEB_01685	5.11e-146	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HMCAFHEB_01686	3.01e-184	-	-	-	-	-	-	-	-
HMCAFHEB_01687	4.42e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMCAFHEB_01688	1.04e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
HMCAFHEB_01689	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
HMCAFHEB_01690	8.06e-175	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
HMCAFHEB_01691	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HMCAFHEB_01692	2.09e-212	-	-	-	P	-	-	-	Cation efflux family
HMCAFHEB_01693	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMCAFHEB_01694	2.72e-282	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HMCAFHEB_01695	1.36e-131	-	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HMCAFHEB_01696	0.0	-	-	-	EK	ko:K05825,ko:K18907	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko00002,ko01000,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HMCAFHEB_01697	2.4e-80	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HMCAFHEB_01698	3.56e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HMCAFHEB_01699	3.22e-139	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HMCAFHEB_01700	1.89e-230	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HMCAFHEB_01701	1.25e-106	-	-	-	O	-	-	-	Hsp20/alpha crystallin family
HMCAFHEB_01702	1.65e-140	-	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HMCAFHEB_01703	3.62e-154	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
HMCAFHEB_01704	0.0	-	-	-	U	ko:K06956	-	ko00000	Sodium:dicarboxylate symporter family
HMCAFHEB_01705	0.0	-	-	-	-	-	-	-	-
HMCAFHEB_01708	3.02e-279	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HMCAFHEB_01709	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
HMCAFHEB_01710	7.42e-41	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
HMCAFHEB_01711	2.69e-256	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
HMCAFHEB_01713	4.27e-309	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HMCAFHEB_01714	8.3e-171	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HMCAFHEB_01716	1.77e-72	-	-	-	L	-	-	-	RelB antitoxin
HMCAFHEB_01717	2.07e-301	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HMCAFHEB_01718	3.18e-16	tam	2.1.1.144	-	S	ko:K00598	-	ko00000,ko01000	Methyltransferase domain
HMCAFHEB_01723	1.61e-48	-	-	-	-	-	-	-	-
HMCAFHEB_01724	0.00013	-	-	-	TV	ko:K05792	-	ko00000	HNH endonuclease
HMCAFHEB_01725	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HMCAFHEB_01727	2.93e-111	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
HMCAFHEB_01728	2.38e-295	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
HMCAFHEB_01729	2.74e-75	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HMCAFHEB_01730	7.38e-85	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HMCAFHEB_01731	3.05e-153	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCAFHEB_01732	1.47e-169	-	-	-	M	-	-	-	Mechanosensitive ion channel
HMCAFHEB_01733	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMCAFHEB_01735	2.84e-199	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
HMCAFHEB_01736	2.16e-144	-	-	-	S	-	-	-	Domain of unknown function (DUF4854)
HMCAFHEB_01737	9.66e-273	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HMCAFHEB_01738	0.0	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
HMCAFHEB_01739	0.0	-	-	-	M	-	-	-	domain protein
HMCAFHEB_01740	2.45e-70	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Acylphosphatase
HMCAFHEB_01741	2.58e-190	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HMCAFHEB_01742	5.99e-237	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HMCAFHEB_01743	1.3e-175	-	-	-	M	-	-	-	Protein of unknown function (DUF3152)
HMCAFHEB_01744	3.99e-176	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HMCAFHEB_01746	5.07e-95	-	-	-	E	-	-	-	Domain of unknown function (DUF5011)
HMCAFHEB_01747	5.39e-32	-	-	-	S	-	-	-	Parallel beta-helix repeats
HMCAFHEB_01750	2.34e-92	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HMCAFHEB_01751	1.51e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMCAFHEB_01752	2.38e-112	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HMCAFHEB_01753	6.47e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HMCAFHEB_01754	6.26e-230	-	-	-	T	-	-	-	Pfam Adenylate and Guanylate cyclase catalytic domain
HMCAFHEB_01755	2.3e-170	-	-	-	-	-	-	-	-
HMCAFHEB_01756	0.0	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HMCAFHEB_01757	5.34e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMCAFHEB_01758	0.0	-	3.2.1.97	GH101	G	ko:K17624	-	ko00000,ko01000	Glycosyl hydrolase 101 beta sandwich domain
HMCAFHEB_01759	1.23e-252	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HMCAFHEB_01760	1.17e-277	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HMCAFHEB_01761	1.38e-227	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HMCAFHEB_01762	1.27e-221	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HMCAFHEB_01763	6.4e-164	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HMCAFHEB_01764	4.95e-44	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HMCAFHEB_01766	7.11e-295	aspC	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
HMCAFHEB_01767	2.13e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMCAFHEB_01768	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMCAFHEB_01769	8.94e-274	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HMCAFHEB_01770	2.12e-53	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
HMCAFHEB_01771	1.44e-62	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HMCAFHEB_01772	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
HMCAFHEB_01773	1.16e-303	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
HMCAFHEB_01774	1.11e-213	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HMCAFHEB_01775	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
HMCAFHEB_01776	3.21e-210	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMCAFHEB_01777	8.09e-76	-	-	-	-	-	-	-	-
HMCAFHEB_01778	4.51e-84	-	-	-	-	-	-	-	-
HMCAFHEB_01779	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
HMCAFHEB_01780	3.72e-237	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HMCAFHEB_01781	1.54e-305	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HMCAFHEB_01782	0.0	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HMCAFHEB_01783	5.94e-107	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HMCAFHEB_01784	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HMCAFHEB_01785	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HMCAFHEB_01786	5.58e-230	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HMCAFHEB_01787	2.69e-82	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
HMCAFHEB_01788	0.0	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
HMCAFHEB_01789	2.86e-57	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
HMCAFHEB_01790	8.89e-111	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HMCAFHEB_01792	1.72e-209	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HMCAFHEB_01793	3.23e-307	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HMCAFHEB_01794	2.24e-103	-	-	-	-	-	-	-	-
HMCAFHEB_01795	1.5e-44	-	-	-	Q	-	-	-	phosphatase activity
HMCAFHEB_01796	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
HMCAFHEB_01797	1.29e-66	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HMCAFHEB_01798	5.95e-65	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMCAFHEB_01799	0.0	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMCAFHEB_01800	3.37e-88	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HMCAFHEB_01801	1.5e-167	-	-	-	K	ko:K03489,ko:K03710	-	ko00000,ko03000	UTRA
HMCAFHEB_01802	8.08e-103	-	-	-	S	-	-	-	FMN_bind
HMCAFHEB_01803	7.76e-191	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCAFHEB_01804	3.5e-276	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HMCAFHEB_01805	1.87e-288	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HMCAFHEB_01806	2.49e-295	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
HMCAFHEB_01807	2.38e-150	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
HMCAFHEB_01808	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
HMCAFHEB_01809	8.33e-31	-	-	-	G	-	-	-	MFS/sugar transport protein
HMCAFHEB_01810	2.9e-256	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMCAFHEB_01811	3.26e-70	-	-	-	S	-	-	-	Fic/DOC family
HMCAFHEB_01813	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMCAFHEB_01814	1.47e-50	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
HMCAFHEB_01815	8.04e-257	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HMCAFHEB_01816	7.37e-273	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HMCAFHEB_01817	3.45e-157	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMCAFHEB_01818	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMCAFHEB_01819	1.87e-250	-	-	-	I	-	-	-	PAP2 superfamily
HMCAFHEB_01820	0.0	-	-	-	M	-	-	-	PA domain
HMCAFHEB_01821	6.63e-175	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
HMCAFHEB_01822	5.17e-295	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HMCAFHEB_01823	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
HMCAFHEB_01824	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HMCAFHEB_01825	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HMCAFHEB_01826	0.0	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
HMCAFHEB_01827	1.77e-148	-	-	-	-	-	-	-	-
HMCAFHEB_01828	7.91e-271	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMCAFHEB_01830	1.42e-126	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HMCAFHEB_01831	2.29e-176	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HMCAFHEB_01832	1.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMCAFHEB_01833	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
HMCAFHEB_01834	1.61e-274	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
HMCAFHEB_01835	1.47e-72	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
HMCAFHEB_01836	1.28e-73	-	-	-	U	-	-	-	TadE-like protein
HMCAFHEB_01837	1.13e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
HMCAFHEB_01838	2.66e-112	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
HMCAFHEB_01839	6.16e-156	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
HMCAFHEB_01840	6.74e-244	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
HMCAFHEB_01841	3.16e-195	-	-	-	D	-	-	-	bacterial-type flagellum organization
HMCAFHEB_01843	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HMCAFHEB_01844	5.71e-257	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
HMCAFHEB_01845	3.04e-129	-	-	-	-	-	-	-	-
HMCAFHEB_01846	1.97e-56	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HMCAFHEB_01847	4.68e-77	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HMCAFHEB_01848	2.34e-267	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
HMCAFHEB_01849	0.0	-	-	-	-	-	-	-	-
HMCAFHEB_01850	0.00015	-	-	-	-	-	-	-	-
HMCAFHEB_01851	1.99e-36	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
HMCAFHEB_01852	1.93e-211	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HMCAFHEB_01853	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HMCAFHEB_01854	2.48e-24	-	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
HMCAFHEB_01855	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
HMCAFHEB_01856	0.0	-	-	-	V	-	-	-	ABC transporter permease
HMCAFHEB_01857	1.03e-272	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HMCAFHEB_01858	2.7e-175	-	-	-	T	ko:K06950	-	ko00000	HD domain
HMCAFHEB_01859	1.42e-212	-	-	-	S	-	-	-	Glutamine amidotransferase domain
HMCAFHEB_01861	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HMCAFHEB_01862	5.49e-237	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HMCAFHEB_01863	4.42e-259	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
HMCAFHEB_01865	1.24e-102	-	-	-	K	-	-	-	Transcriptional regulator
HMCAFHEB_01866	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMCAFHEB_01867	1.14e-171	-	-	-	-	-	-	-	-
HMCAFHEB_01868	6.51e-83	-	-	-	-	-	-	-	-
HMCAFHEB_01869	2.05e-224	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMCAFHEB_01870	1.05e-161	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HMCAFHEB_01872	1.42e-172	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HMCAFHEB_01873	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR Asp-box repeat
HMCAFHEB_01874	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
HMCAFHEB_01875	6.42e-112	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
HMCAFHEB_01876	1.35e-236	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
HMCAFHEB_01877	3.29e-80	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMCAFHEB_01878	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HMCAFHEB_01879	0.0	strK	3.1.3.1, 3.1.3.39	-	P	ko:K01077,ko:K04342	ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
HMCAFHEB_01880	3.34e-244	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HMCAFHEB_01882	1.02e-171	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
HMCAFHEB_01883	9.49e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
HMCAFHEB_01884	3.27e-183	nfrA	-	-	C	-	-	-	Nitroreductase family
HMCAFHEB_01885	2.45e-61	-	-	-	-	-	-	-	-
HMCAFHEB_01886	1.38e-75	-	-	-	L	ko:K07496	-	ko00000	TIGRFAM transposase, IS605 OrfB family
HMCAFHEB_01887	1.54e-59	-	-	-	L	-	-	-	PFAM Resolvase, N-terminal
HMCAFHEB_01889	1.16e-168	-	-	-	L	-	-	-	Putative transposase DNA-binding domain
HMCAFHEB_01890	3.69e-99	-	-	-	L	-	-	-	Resolvase, N terminal domain
HMCAFHEB_01893	1.49e-75	-	-	-	L	-	-	-	Initiator Replication protein
HMCAFHEB_01895	1.45e-63	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HMCAFHEB_01897	3.98e-40	-	-	-	D	-	-	-	MobA MobL family protein
HMCAFHEB_01898	1.18e-258	-	-	-	L	-	-	-	Transposase
HMCAFHEB_01899	1.59e-221	-	-	-	L	-	-	-	Transposase, Mutator family
HMCAFHEB_01900	1.57e-34	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein