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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
DGNHLHCD_00001	0.0	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
DGNHLHCD_00002	1.83e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DGNHLHCD_00003	6.67e-173	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
DGNHLHCD_00004	3.24e-272	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
DGNHLHCD_00005	2.46e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
DGNHLHCD_00006	1.04e-46	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
DGNHLHCD_00011	3.96e-44	-	-	-	-	-	-	-	-
DGNHLHCD_00017	0.000121	xerC	-	-	D	ko:K03733	-	ko00000,ko03036	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids
DGNHLHCD_00018	1.06e-57	pacL	3.6.3.8, 3.6.3.9	-	P	ko:K01537,ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	ko00000,ko00001,ko01000,ko04147	ATPase, P-type transporting, HAD superfamily, subfamily IC
DGNHLHCD_00019	8.41e-298	-	-	-	T	-	-	-	Histidine kinase
DGNHLHCD_00020	1.54e-153	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
DGNHLHCD_00021	4.91e-150	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
DGNHLHCD_00022	7.55e-243	pitB	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
DGNHLHCD_00023	1.63e-107	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
DGNHLHCD_00024	6.69e-61	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
DGNHLHCD_00025	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
DGNHLHCD_00026	0.0	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
DGNHLHCD_00027	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
DGNHLHCD_00028	5.33e-36	-	-	-	-	-	-	-	-
DGNHLHCD_00029	9.88e-180	-	-	-	-	-	-	-	-
DGNHLHCD_00030	6.15e-84	-	-	-	S	-	-	-	PrgI family protein
DGNHLHCD_00031	0.0	-	-	-	U	-	-	-	type IV secretory pathway VirB4
DGNHLHCD_00033	0.0	-	-	-	S	-	-	-	zinc finger
DGNHLHCD_00034	1.58e-160	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DGNHLHCD_00035	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DGNHLHCD_00037	1.06e-121	-	-	-	-	-	-	-	-
DGNHLHCD_00038	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DGNHLHCD_00039	7.54e-240	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
DGNHLHCD_00043	0.0	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DGNHLHCD_00044	4.96e-190	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
DGNHLHCD_00045	1.62e-109	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DGNHLHCD_00046	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
DGNHLHCD_00047	5.17e-56	-	-	-	-	-	-	-	-
DGNHLHCD_00048	1.15e-165	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
DGNHLHCD_00049	9.44e-187	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
DGNHLHCD_00052	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
DGNHLHCD_00053	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DGNHLHCD_00054	6.97e-208	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DGNHLHCD_00055	2.35e-169	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DGNHLHCD_00056	5.9e-76	-	-	-	L	-	-	-	Transposase
DGNHLHCD_00057	3.22e-33	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
DGNHLHCD_00058	1.03e-55	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
DGNHLHCD_00059	6.14e-87	gsiA	-	-	P	ko:K02031,ko:K02032,ko:K12371,ko:K13892	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
DGNHLHCD_00060	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
DGNHLHCD_00061	5.54e-210	-	-	-	K	-	-	-	-acetyltransferase
DGNHLHCD_00062	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
DGNHLHCD_00063	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
DGNHLHCD_00065	0.0	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
DGNHLHCD_00066	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
DGNHLHCD_00067	0.0	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
DGNHLHCD_00068	1.41e-302	-	-	-	S	-	-	-	Protein of unknown function DUF58
DGNHLHCD_00069	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
DGNHLHCD_00070	1.65e-211	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
DGNHLHCD_00071	1.47e-101	-	-	-	B	-	-	-	Belongs to the OprB family
DGNHLHCD_00072	2.55e-122	-	-	-	T	-	-	-	Forkhead associated domain
DGNHLHCD_00073	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DGNHLHCD_00074	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DGNHLHCD_00075	1.31e-142	-	-	-	-	-	-	-	-
DGNHLHCD_00076	3.13e-237	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
DGNHLHCD_00077	6.25e-59	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	Putative cell wall binding repeat
DGNHLHCD_00078	9.1e-157	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DGNHLHCD_00080	2.29e-93	-	-	-	-	-	-	-	-
DGNHLHCD_00081	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
DGNHLHCD_00082	3.23e-58	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
DGNHLHCD_00083	1.32e-308	-	-	-	EGP	-	-	-	Sugar (and other) transporter
DGNHLHCD_00084	2.4e-296	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
DGNHLHCD_00085	1.99e-219	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
DGNHLHCD_00086	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
DGNHLHCD_00087	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
DGNHLHCD_00089	1.6e-204	-	-	-	L	ko:K07493	-	ko00000	PFAM Transposase, Mutator family
DGNHLHCD_00090	8.21e-48	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
DGNHLHCD_00091	1.74e-75	-	-	-	S	-	-	-	pathogenesis
DGNHLHCD_00092	6.03e-86	-	-	-	-	-	-	-	-
DGNHLHCD_00095	1.71e-116	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
DGNHLHCD_00096	6.85e-214	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
DGNHLHCD_00097	3.19e-125	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
DGNHLHCD_00099	4.83e-133	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
DGNHLHCD_00100	2e-303	-	-	-	V	-	-	-	MatE
DGNHLHCD_00101	2.01e-23	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DGNHLHCD_00102	3.05e-170	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DGNHLHCD_00103	2.59e-145	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
DGNHLHCD_00104	1.03e-141	-	-	-	-	-	-	-	-
DGNHLHCD_00105	1.83e-244	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
DGNHLHCD_00106	8.11e-282	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
DGNHLHCD_00107	3.41e-136	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DGNHLHCD_00109	5.43e-179	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
DGNHLHCD_00110	3.37e-270	-	-	-	E	-	-	-	Aminotransferase class I and II
DGNHLHCD_00111	3.64e-177	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
DGNHLHCD_00112	7.76e-282	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DGNHLHCD_00113	5.57e-118	-	-	-	-	-	-	-	-
DGNHLHCD_00114	9.29e-79	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
DGNHLHCD_00115	2.48e-150	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
DGNHLHCD_00116	9.36e-310	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DGNHLHCD_00117	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
DGNHLHCD_00120	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
DGNHLHCD_00121	0.0	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
DGNHLHCD_00122	5.13e-213	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
DGNHLHCD_00123	3.31e-35	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
DGNHLHCD_00124	5.46e-81	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DGNHLHCD_00125	9.73e-228	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
DGNHLHCD_00126	1.86e-194	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
DGNHLHCD_00127	9.67e-49	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
DGNHLHCD_00128	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
DGNHLHCD_00129	2.66e-76	yccF	-	-	S	-	-	-	Inner membrane component domain
DGNHLHCD_00130	1.9e-17	-	-	-	-	-	-	-	-
DGNHLHCD_00131	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
DGNHLHCD_00132	7.04e-57	-	-	-	L	-	-	-	Integrase core domain
DGNHLHCD_00133	9.32e-41	istB	-	-	L	-	-	-	IstB-like ATP binding protein
DGNHLHCD_00134	5.29e-101	-	-	-	V	ko:K06147	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
DGNHLHCD_00135	5.53e-96	-	-	-	I	-	-	-	Sterol carrier protein
DGNHLHCD_00136	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DGNHLHCD_00137	7.68e-47	-	-	-	-	-	-	-	-
DGNHLHCD_00138	3.41e-186	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
DGNHLHCD_00140	0.0	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
DGNHLHCD_00141	8.05e-100	crgA	-	-	D	-	-	-	Involved in cell division
DGNHLHCD_00142	2.05e-183	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
DGNHLHCD_00143	2.68e-294	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
DGNHLHCD_00144	9.5e-156	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
DGNHLHCD_00145	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
DGNHLHCD_00146	5.69e-234	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
DGNHLHCD_00147	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
DGNHLHCD_00148	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
DGNHLHCD_00149	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
DGNHLHCD_00150	1.44e-122	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
DGNHLHCD_00151	6.12e-166	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
DGNHLHCD_00152	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
DGNHLHCD_00153	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
DGNHLHCD_00154	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
DGNHLHCD_00155	5.58e-33	-	-	-	S	-	-	-	Adenine-specific methyltransferase EcoRI
DGNHLHCD_00156	1.43e-223	tnp3521a2	-	-	L	-	-	-	Integrase core domain
DGNHLHCD_00157	1.23e-61	-	-	-	L	ko:K07483	-	ko00000	Transposase
DGNHLHCD_00158	2.95e-84	-	-	-	D	-	-	-	MobA/MobL family
DGNHLHCD_00159	2.74e-101	-	-	-	-	-	-	-	-
DGNHLHCD_00163	0.0	-	-	-	-	-	-	-	-
DGNHLHCD_00165	1.28e-185	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
DGNHLHCD_00166	1.58e-240	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
DGNHLHCD_00167	4.44e-149	-	-	-	M	-	-	-	CHAP domain
DGNHLHCD_00169	1.01e-213	-	-	-	-	ko:K03646	-	ko00000,ko02000	-
DGNHLHCD_00172	1.8e-171	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
DGNHLHCD_00177	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
DGNHLHCD_00178	1.2e-19	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
DGNHLHCD_00179	4.54e-53	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
DGNHLHCD_00183	4.85e-185	istB	-	-	L	-	-	-	IstB-like ATP binding protein
DGNHLHCD_00184	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
DGNHLHCD_00185	1.11e-214	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
DGNHLHCD_00186	3.93e-223	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DGNHLHCD_00187	3.83e-314	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
DGNHLHCD_00188	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DGNHLHCD_00189	4.17e-97	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DGNHLHCD_00190	3.67e-179	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DGNHLHCD_00191	4.94e-288	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DGNHLHCD_00192	1.27e-226	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
DGNHLHCD_00193	4.41e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DGNHLHCD_00194	6.31e-171	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
DGNHLHCD_00195	3.84e-165	-	-	-	S	-	-	-	alpha beta
DGNHLHCD_00196	4.78e-188	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DGNHLHCD_00197	1.78e-187	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
DGNHLHCD_00198	4.26e-113	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DGNHLHCD_00199	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
DGNHLHCD_00200	3.59e-118	-	-	-	-	-	-	-	-
DGNHLHCD_00201	1.59e-255	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
DGNHLHCD_00202	1.35e-306	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
DGNHLHCD_00203	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
DGNHLHCD_00204	0.0	fadD1	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
DGNHLHCD_00205	2.51e-164	-	-	-	M	-	-	-	Peptidase family M23
DGNHLHCD_00207	3.95e-251	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DGNHLHCD_00208	9.98e-134	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
DGNHLHCD_00209	3.44e-204	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
DGNHLHCD_00210	1.81e-152	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
DGNHLHCD_00211	1.05e-231	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
DGNHLHCD_00212	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
DGNHLHCD_00213	4.25e-164	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
DGNHLHCD_00214	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
DGNHLHCD_00215	0.0	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
DGNHLHCD_00216	5.19e-134	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
DGNHLHCD_00221	3.45e-85	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
DGNHLHCD_00222	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
DGNHLHCD_00223	1.93e-131	-	-	-	D	-	-	-	Septum formation initiator
DGNHLHCD_00224	7.41e-315	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DGNHLHCD_00230	4.61e-80	-	-	-	K	-	-	-	Helix-turn-helix domain protein
DGNHLHCD_00231	9.53e-88	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DGNHLHCD_00232	5.01e-311	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DGNHLHCD_00234	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DGNHLHCD_00236	1.07e-35	-	-	-	-	-	-	-	-
DGNHLHCD_00237	3.92e-37	-	-	-	L	-	-	-	DNA integration
DGNHLHCD_00238	7.23e-35	-	-	-	-	-	-	-	-
DGNHLHCD_00241	8.57e-222	-	-	-	K	-	-	-	Putative sugar-binding domain
DGNHLHCD_00242	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DGNHLHCD_00243	0.0	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DGNHLHCD_00244	1.13e-29	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	Cation transporting ATPase, C-terminus
DGNHLHCD_00245	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	Cation transporting ATPase, C-terminus
DGNHLHCD_00246	2.62e-157	mgtC	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
DGNHLHCD_00248	6.19e-263	-	-	-	-	-	-	-	-
DGNHLHCD_00250	1.21e-271	-	-	-	-	-	-	-	-
DGNHLHCD_00251	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
DGNHLHCD_00255	3.96e-228	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
DGNHLHCD_00256	9.76e-153	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DGNHLHCD_00257	6.69e-173	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DGNHLHCD_00258	1.65e-314	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DGNHLHCD_00260	5.15e-118	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
DGNHLHCD_00261	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
DGNHLHCD_00262	5.36e-65	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DGNHLHCD_00263	1.67e-100	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DGNHLHCD_00264	2.72e-34	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
DGNHLHCD_00265	3.08e-147	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
DGNHLHCD_00266	2.47e-183	-	-	-	-	-	-	-	-
DGNHLHCD_00267	2.77e-105	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DGNHLHCD_00268	1.04e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
DGNHLHCD_00269	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
DGNHLHCD_00270	8.06e-175	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
DGNHLHCD_00271	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
DGNHLHCD_00272	4.14e-212	-	-	-	P	-	-	-	Cation efflux family
DGNHLHCD_00273	1.91e-57	-	-	-	-	-	-	-	-
DGNHLHCD_00274	8.56e-119	-	-	-	S	-	-	-	Transcription factor WhiB
DGNHLHCD_00275	2.09e-150	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
DGNHLHCD_00276	2.77e-193	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
DGNHLHCD_00278	1.55e-35	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
DGNHLHCD_00279	4.05e-303	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
DGNHLHCD_00280	2.36e-46	-	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
DGNHLHCD_00281	1.72e-48	-	-	-	-	-	-	-	-
DGNHLHCD_00282	1.5e-96	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
DGNHLHCD_00283	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DGNHLHCD_00284	1.39e-179	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
DGNHLHCD_00285	1.15e-174	-	2.7.13.3	-	T	ko:K18351	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
DGNHLHCD_00287	2.23e-234	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
DGNHLHCD_00288	5.16e-80	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
DGNHLHCD_00290	2.25e-194	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
DGNHLHCD_00293	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
DGNHLHCD_00294	1.72e-20	-	-	-	S	ko:K18955	-	ko00000,ko03000	Transcription factor WhiB
DGNHLHCD_00296	1.18e-223	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DGNHLHCD_00297	5.63e-255	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
DGNHLHCD_00298	2.87e-110	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
DGNHLHCD_00301	1.48e-271	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
DGNHLHCD_00302	5.42e-227	-	-	-	M	-	-	-	Glycosyltransferase like family 2
DGNHLHCD_00303	0.0	-	-	-	S	-	-	-	AI-2E family transporter
DGNHLHCD_00304	3.97e-295	-	-	-	M	-	-	-	Glycosyl transferase family 21
DGNHLHCD_00305	2.26e-215	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DGNHLHCD_00306	0.0	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
DGNHLHCD_00307	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
DGNHLHCD_00308	3.48e-269	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DGNHLHCD_00309	2.65e-127	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
DGNHLHCD_00310	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DGNHLHCD_00311	2.05e-130	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
DGNHLHCD_00312	3.21e-210	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DGNHLHCD_00313	0.0	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DGNHLHCD_00314	5.53e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
DGNHLHCD_00315	3.78e-219	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
DGNHLHCD_00316	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
DGNHLHCD_00317	5.71e-240	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
DGNHLHCD_00318	3.85e-196	-	-	-	D	-	-	-	bacterial-type flagellum organization
DGNHLHCD_00319	3.24e-169	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
DGNHLHCD_00320	2.16e-93	vpr	-	-	O	-	-	-	Subtilase family
DGNHLHCD_00321	4.45e-21	-	-	-	-	-	-	-	-
DGNHLHCD_00323	4.51e-279	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
DGNHLHCD_00328	3.62e-47	-	-	-	-	-	-	-	-
DGNHLHCD_00330	0.0	-	2.7.1.53	-	G	ko:K00880	ko00040,ko00053,map00040,map00053	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
DGNHLHCD_00331	6.29e-220	-	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
DGNHLHCD_00332	2.41e-166	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Class II Aldolase and Adducin N-terminal domain
DGNHLHCD_00333	2.33e-81	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DGNHLHCD_00334	4.9e-200	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
DGNHLHCD_00335	6.64e-170	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DGNHLHCD_00336	1.26e-266	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
DGNHLHCD_00337	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
DGNHLHCD_00338	8.26e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DGNHLHCD_00339	2.33e-143	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DGNHLHCD_00342	3.25e-218	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
DGNHLHCD_00343	1.55e-134	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
DGNHLHCD_00344	2.28e-258	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
DGNHLHCD_00345	1.24e-13	chiA	3.1.6.1, 3.2.1.14, 3.2.1.17, 3.2.1.23, 3.2.1.4	AA10,CBM15,CBM73,GH18,GH5,GH9	S	ko:K01130,ko:K01179,ko:K01183,ko:K01190,ko:K03933,ko:K12308,ko:K13381	ko00052,ko00140,ko00500,ko00511,ko00520,ko00600,ko01100,map00052,map00140,map00500,map00511,map00520,map00600,map01100	ko00000,ko00001,ko01000	dextransucrase activity
DGNHLHCD_00346	5.17e-218	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
DGNHLHCD_00347	5.2e-173	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
DGNHLHCD_00348	1.39e-295	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
DGNHLHCD_00349	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
DGNHLHCD_00350	2.78e-177	rfbP	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
DGNHLHCD_00351	2.14e-119	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DGNHLHCD_00352	5.42e-29	-	-	-	S	-	-	-	Protein of unknown function (DUF4127)
DGNHLHCD_00353	1.49e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF4127)
DGNHLHCD_00354	1.65e-72	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
DGNHLHCD_00355	3.23e-108	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DGNHLHCD_00358	3.65e-95	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
DGNHLHCD_00359	2.2e-166	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
DGNHLHCD_00360	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
DGNHLHCD_00361	6.52e-307	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
DGNHLHCD_00362	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DGNHLHCD_00363	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
DGNHLHCD_00364	1.62e-193	-	-	-	S	-	-	-	Amidohydrolase family
DGNHLHCD_00365	1.68e-65	-	-	-	S	-	-	-	Amidohydrolase family
DGNHLHCD_00366	4.09e-249	-	-	-	S	-	-	-	Protein conserved in bacteria
DGNHLHCD_00367	2.32e-259	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
DGNHLHCD_00368	1.81e-65	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
DGNHLHCD_00369	3.87e-113	-	-	-	K	-	-	-	LytTr DNA-binding domain
DGNHLHCD_00370	6.62e-131	-	-	-	T	-	-	-	protein histidine kinase activity
DGNHLHCD_00371	5.04e-260	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DGNHLHCD_00372	8.14e-39	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
DGNHLHCD_00373	6.45e-116	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
DGNHLHCD_00374	6.09e-255	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
DGNHLHCD_00375	3.7e-137	-	-	-	M	-	-	-	Glycosyl transferase family 2
DGNHLHCD_00376	0.0	-	-	-	-	-	-	-	-
DGNHLHCD_00377	3.83e-259	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DGNHLHCD_00378	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
DGNHLHCD_00379	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
DGNHLHCD_00380	2.33e-09	-	-	-	S	-	-	-	Spermine/spermidine synthase domain
DGNHLHCD_00382	3.41e-172	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
DGNHLHCD_00383	1.96e-253	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DGNHLHCD_00384	2.32e-126	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DGNHLHCD_00385	3.63e-228	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DGNHLHCD_00386	2.64e-248	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
DGNHLHCD_00387	9.61e-84	-	-	-	-	-	-	-	-
DGNHLHCD_00388	1.53e-162	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
DGNHLHCD_00389	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DGNHLHCD_00390	5.99e-243	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
DGNHLHCD_00391	1.13e-291	-	2.6.1.33	-	M	ko:K20429	-	ko00000,ko01000	DegT/DnrJ/EryC1/StrS aminotransferase family
DGNHLHCD_00392	4.4e-310	-	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp
DGNHLHCD_00393	1.46e-165	-	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
DGNHLHCD_00394	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
DGNHLHCD_00395	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
DGNHLHCD_00397	6.19e-125	-	-	-	F	-	-	-	NUDIX domain
DGNHLHCD_00398	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
DGNHLHCD_00399	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
DGNHLHCD_00400	4.36e-248	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DGNHLHCD_00401	3.06e-242	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DGNHLHCD_00402	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
DGNHLHCD_00403	5.53e-210	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
DGNHLHCD_00404	7.19e-298	iscS1	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
DGNHLHCD_00405	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
DGNHLHCD_00406	3.4e-105	-	-	-	-	-	-	-	-
DGNHLHCD_00407	1.68e-252	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
DGNHLHCD_00408	8.53e-245	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
DGNHLHCD_00409	2.67e-56	-	-	-	-	-	-	-	-
DGNHLHCD_00410	1.73e-238	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
DGNHLHCD_00411	4.8e-226	oppB1	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DGNHLHCD_00412	5.29e-212	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
DGNHLHCD_00413	0.0	oppD	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
DGNHLHCD_00414	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
DGNHLHCD_00415	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
DGNHLHCD_00416	8.58e-217	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
DGNHLHCD_00417	2.66e-196	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
DGNHLHCD_00418	1.08e-171	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
DGNHLHCD_00419	1.59e-314	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DGNHLHCD_00420	4.03e-143	-	-	-	-	-	-	-	-
DGNHLHCD_00421	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
DGNHLHCD_00423	1.16e-35	-	-	-	S	-	-	-	Putative ABC-transporter type IV
DGNHLHCD_00424	2.01e-208	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DGNHLHCD_00426	4.77e-91	-	-	-	E	-	-	-	IrrE N-terminal-like domain
DGNHLHCD_00427	3.13e-104	-	-	-	K	-	-	-	Winged helix DNA-binding domain
DGNHLHCD_00428	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
DGNHLHCD_00429	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
DGNHLHCD_00430	1.23e-109	-	-	-	-	-	-	-	-
DGNHLHCD_00431	7.92e-23	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
DGNHLHCD_00433	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
DGNHLHCD_00434	0.0	-	-	-	S	-	-	-	Glycosyl hydrolases related to GH101 family, GH129
DGNHLHCD_00435	1.96e-254	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
DGNHLHCD_00436	1.17e-172	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DGNHLHCD_00438	2.77e-273	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DGNHLHCD_00439	8.54e-305	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
DGNHLHCD_00440	2.56e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
DGNHLHCD_00441	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
DGNHLHCD_00443	0.0	dinF	-	-	V	-	-	-	MatE
DGNHLHCD_00444	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
DGNHLHCD_00445	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
DGNHLHCD_00446	1.02e-181	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
DGNHLHCD_00447	5.22e-43	-	-	-	S	-	-	-	granule-associated protein
DGNHLHCD_00448	8.32e-96	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
DGNHLHCD_00449	1.25e-82	-	-	-	-	-	-	-	-
DGNHLHCD_00451	2.3e-226	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DGNHLHCD_00452	1.32e-147	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DGNHLHCD_00453	1.65e-191	-	-	-	V	-	-	-	DivIVA protein
DGNHLHCD_00454	1.35e-56	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
DGNHLHCD_00455	9.4e-105	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DGNHLHCD_00456	5.42e-293	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DGNHLHCD_00457	4.69e-314	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DGNHLHCD_00458	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
DGNHLHCD_00459	2.08e-79	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
DGNHLHCD_00466	1.5e-203	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DGNHLHCD_00467	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DGNHLHCD_00468	1.62e-110	-	-	-	-	-	-	-	-
DGNHLHCD_00469	3.43e-291	-	-	-	O	ko:K13525	ko04141,ko05134,map04141,map05134	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	AAA domain (Cdc48 subfamily)
DGNHLHCD_00470	2.08e-210	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
DGNHLHCD_00471	1.25e-80	-	-	-	S	-	-	-	Thiamine-binding protein
DGNHLHCD_00472	4.8e-249	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
DGNHLHCD_00473	2.24e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
DGNHLHCD_00474	2.91e-193	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
DGNHLHCD_00475	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
DGNHLHCD_00476	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
DGNHLHCD_00477	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
DGNHLHCD_00478	9.31e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
DGNHLHCD_00479	2.09e-212	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
DGNHLHCD_00480	4.82e-147	-	-	-	S	-	-	-	Vitamin K epoxide reductase
DGNHLHCD_00481	1.72e-214	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
DGNHLHCD_00482	3.31e-197	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
DGNHLHCD_00483	5.55e-221	-	-	-	S	-	-	-	Patatin-like phospholipase
DGNHLHCD_00484	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
DGNHLHCD_00485	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
DGNHLHCD_00486	4.46e-118	-	-	-	K	-	-	-	MarR family
DGNHLHCD_00487	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
DGNHLHCD_00488	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
DGNHLHCD_00489	4.36e-210	-	-	-	-	-	-	-	-
DGNHLHCD_00490	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
DGNHLHCD_00492	5.91e-179	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DGNHLHCD_00493	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
DGNHLHCD_00494	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DGNHLHCD_00495	5.97e-56	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DGNHLHCD_00496	3.47e-218	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
DGNHLHCD_00498	2.73e-233	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
DGNHLHCD_00499	0.0	-	-	-	OP	-	-	-	Sulfurtransferase TusA
DGNHLHCD_00500	8.74e-193	thiF	2.7.7.73, 2.7.7.80, 2.8.1.11	-	H	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
DGNHLHCD_00501	4.8e-171	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
DGNHLHCD_00502	1.3e-200	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
DGNHLHCD_00503	7.65e-293	aspB	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class-V
DGNHLHCD_00504	1.66e-58	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
DGNHLHCD_00505	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DGNHLHCD_00506	3.31e-171	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DGNHLHCD_00507	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
DGNHLHCD_00509	1.94e-248	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DGNHLHCD_00510	5.26e-281	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
DGNHLHCD_00511	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DGNHLHCD_00512	2.46e-291	-	-	-	G	-	-	-	Transmembrane secretion effector
DGNHLHCD_00513	1.69e-169	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DGNHLHCD_00514	1.37e-184	-	-	-	-	-	-	-	-
DGNHLHCD_00515	1.43e-95	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DGNHLHCD_00516	1.23e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DGNHLHCD_00517	8.52e-221	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
DGNHLHCD_00518	1.99e-240	-	-	-	-	-	-	-	-
DGNHLHCD_00519	8.35e-232	-	-	-	-	-	-	-	-
DGNHLHCD_00520	1.03e-213	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
DGNHLHCD_00521	3.33e-153	-	-	-	S	-	-	-	CYTH
DGNHLHCD_00523	4.87e-236	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
DGNHLHCD_00524	1.17e-25	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	carboxylic acid catabolic process
DGNHLHCD_00525	1.58e-83	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
DGNHLHCD_00526	2.84e-194	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
DGNHLHCD_00529	8.95e-192	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
DGNHLHCD_00530	2.69e-82	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
DGNHLHCD_00531	3.93e-230	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
DGNHLHCD_00532	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
DGNHLHCD_00533	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DGNHLHCD_00534	5.94e-107	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
DGNHLHCD_00535	0.0	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
DGNHLHCD_00536	6.26e-305	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
DGNHLHCD_00537	1.3e-237	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DGNHLHCD_00538	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
DGNHLHCD_00539	3.3e-86	-	-	-	-	-	-	-	-
DGNHLHCD_00540	2.73e-76	-	-	-	-	-	-	-	-
DGNHLHCD_00541	1.07e-208	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DGNHLHCD_00542	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
DGNHLHCD_00543	3.87e-56	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
DGNHLHCD_00544	1.16e-241	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
DGNHLHCD_00545	2.87e-221	-	-	-	-	-	-	-	-
DGNHLHCD_00546	1.43e-56	tnp3503b	-	-	L	-	-	-	Transposase and inactivated derivatives
DGNHLHCD_00547	2.31e-35	-	-	-	-	-	-	-	-
DGNHLHCD_00549	9.14e-198	-	-	-	E	-	-	-	Transglutaminase/protease-like homologues
DGNHLHCD_00550	0.0	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
DGNHLHCD_00551	4.08e-221	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DGNHLHCD_00552	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
DGNHLHCD_00553	3.77e-95	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
DGNHLHCD_00554	1.4e-236	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DGNHLHCD_00555	7.34e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DGNHLHCD_00556	6.96e-83	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DGNHLHCD_00557	1.03e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
DGNHLHCD_00558	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DGNHLHCD_00559	4.79e-129	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DGNHLHCD_00560	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DGNHLHCD_00561	1.51e-94	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
DGNHLHCD_00562	1.46e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
DGNHLHCD_00563	2.04e-149	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DGNHLHCD_00564	1.53e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DGNHLHCD_00565	2.69e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DGNHLHCD_00566	9.65e-91	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DGNHLHCD_00567	7.06e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DGNHLHCD_00568	1.6e-133	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DGNHLHCD_00569	9.32e-70	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DGNHLHCD_00570	7.32e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DGNHLHCD_00571	9.4e-57	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DGNHLHCD_00572	6.77e-51	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
DGNHLHCD_00573	1.1e-58	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DGNHLHCD_00574	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DGNHLHCD_00575	0.0	-	-	-	S	-	-	-	domain protein
DGNHLHCD_00576	9.37e-96	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
DGNHLHCD_00577	7.67e-118	lrp_3	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
DGNHLHCD_00578	8.68e-299	-	2.6.1.1	-	E	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
DGNHLHCD_00579	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DGNHLHCD_00580	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
DGNHLHCD_00581	6.51e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
DGNHLHCD_00582	1.96e-251	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
DGNHLHCD_00583	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DGNHLHCD_00584	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DGNHLHCD_00585	3.33e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DGNHLHCD_00586	7.84e-81	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
DGNHLHCD_00587	4.24e-78	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
DGNHLHCD_00588	1.94e-213	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
DGNHLHCD_00589	2.47e-164	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DGNHLHCD_00590	2.51e-298	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
DGNHLHCD_00591	6.68e-57	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
DGNHLHCD_00592	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
DGNHLHCD_00593	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
DGNHLHCD_00594	6.21e-241	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DGNHLHCD_00595	1.29e-198	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
DGNHLHCD_00596	1.61e-182	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
DGNHLHCD_00597	3.54e-208	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DGNHLHCD_00598	5.73e-217	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DGNHLHCD_00599	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
DGNHLHCD_00600	2.65e-184	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DGNHLHCD_00601	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
DGNHLHCD_00602	1.13e-82	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	carbohydrate transport
DGNHLHCD_00603	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
DGNHLHCD_00604	3.47e-159	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
DGNHLHCD_00605	8.85e-243	-	-	-	K	-	-	-	Periplasmic binding protein domain
DGNHLHCD_00606	2.47e-26	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
DGNHLHCD_00607	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
DGNHLHCD_00609	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DGNHLHCD_00610	4.8e-73	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
DGNHLHCD_00611	0.0	aldH	1.2.1.3, 1.2.99.10	-	C	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase family
DGNHLHCD_00612	1.77e-178	hflK	-	-	O	-	-	-	prohibitin homologues
DGNHLHCD_00613	3.66e-310	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
DGNHLHCD_00614	1.82e-297	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
DGNHLHCD_00615	0.0	nox	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
DGNHLHCD_00616	6.07e-165	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
DGNHLHCD_00617	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DGNHLHCD_00618	2.26e-210	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
DGNHLHCD_00619	1.12e-246	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DGNHLHCD_00620	8.92e-144	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
DGNHLHCD_00621	1.2e-54	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
DGNHLHCD_00622	1.07e-200	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
DGNHLHCD_00623	2.22e-151	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DGNHLHCD_00624	2.27e-222	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
DGNHLHCD_00625	2.78e-57	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
DGNHLHCD_00626	4.58e-181	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
DGNHLHCD_00627	2.88e-96	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
DGNHLHCD_00628	1.19e-154	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DGNHLHCD_00629	8.13e-82	-	-	-	-	-	-	-	-
DGNHLHCD_00631	1.48e-31	-	-	-	L	-	-	-	DNA integration
DGNHLHCD_00632	4.36e-162	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
DGNHLHCD_00633	3.01e-117	-	-	-	K	-	-	-	Putative zinc ribbon domain
DGNHLHCD_00635	2.42e-182	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
DGNHLHCD_00636	1.11e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
DGNHLHCD_00637	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
DGNHLHCD_00638	2.14e-69	-	-	-	-	-	-	-	-
DGNHLHCD_00639	0.0	-	-	-	K	-	-	-	WYL domain
DGNHLHCD_00640	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
DGNHLHCD_00642	1.39e-112	dkg	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
DGNHLHCD_00643	7.98e-123	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
DGNHLHCD_00644	9.51e-55	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DGNHLHCD_00645	5.57e-33	-	-	-	S	-	-	-	Rard protein
DGNHLHCD_00646	8.77e-114	-	-	-	E	-	-	-	Rard protein
DGNHLHCD_00647	2.68e-39	-	-	-	-	-	-	-	-
DGNHLHCD_00648	0.0	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
DGNHLHCD_00649	2.29e-70	-	-	-	V	-	-	-	Abi-like protein
DGNHLHCD_00650	2.59e-247	-	-	-	L	ko:K07485	-	ko00000	Transposase
DGNHLHCD_00651	1.68e-52	-	-	-	L	-	-	-	Helix-turn-helix domain
DGNHLHCD_00652	1.58e-239	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DGNHLHCD_00653	4.39e-145	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
DGNHLHCD_00654	2.84e-202	-	-	-	S	ko:K11206	-	ko00000,ko01000	Carbon-nitrogen hydrolase
DGNHLHCD_00655	5.7e-232	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
DGNHLHCD_00656	1.37e-311	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
DGNHLHCD_00657	5.23e-107	-	-	-	-	-	-	-	-
DGNHLHCD_00658	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
DGNHLHCD_00659	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
DGNHLHCD_00660	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
DGNHLHCD_00661	4.25e-216	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
DGNHLHCD_00662	5.6e-140	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DGNHLHCD_00663	1.41e-232	-	-	-	-	-	-	-	-
DGNHLHCD_00664	1.23e-136	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
DGNHLHCD_00665	1.84e-220	-	-	-	L	-	-	-	Replication initiation factor
DGNHLHCD_00666	1.96e-29	-	-	-	S	-	-	-	Excisionase from transposon Tn916
DGNHLHCD_00667	2.36e-215	-	-	-	L	-	-	-	Phage integrase family
DGNHLHCD_00668	4.95e-18	-	-	-	S	ko:K07149	-	ko00000	Membrane
DGNHLHCD_00669	5.7e-313	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
DGNHLHCD_00670	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DGNHLHCD_00671	3.91e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
DGNHLHCD_00672	1.61e-175	-	-	-	S	-	-	-	UPF0126 domain
DGNHLHCD_00673	1.65e-61	-	-	-	S	-	-	-	phosphoesterase or phosphohydrolase
DGNHLHCD_00674	1.58e-287	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
DGNHLHCD_00675	1.66e-128	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DGNHLHCD_00676	2.09e-242	-	-	-	S	ko:K06889	-	ko00000	alpha beta
DGNHLHCD_00677	1.07e-133	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DGNHLHCD_00679	1.18e-223	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
DGNHLHCD_00680	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
DGNHLHCD_00681	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
DGNHLHCD_00682	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
DGNHLHCD_00683	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DGNHLHCD_00685	2.83e-113	-	-	-	Q	-	-	-	Acetyltransferase (GNAT) domain
DGNHLHCD_00686	3.19e-201	-	-	-	I	-	-	-	Serine aminopeptidase, S33
DGNHLHCD_00687	3.02e-70	-	-	-	S	-	-	-	Putative heavy-metal-binding
DGNHLHCD_00688	5.13e-60	-	-	-	D	-	-	-	DivIVA domain protein
DGNHLHCD_00689	3.72e-116	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
DGNHLHCD_00690	0.0	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
DGNHLHCD_00692	2.37e-250	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DGNHLHCD_00694	1.92e-146	-	-	-	-	-	-	-	-
DGNHLHCD_00695	2.61e-206	-	-	-	EG	-	-	-	EamA-like transporter family
DGNHLHCD_00696	3.7e-262	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
DGNHLHCD_00697	7.85e-282	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
DGNHLHCD_00698	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
DGNHLHCD_00699	9.62e-142	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
DGNHLHCD_00700	1.02e-184	-	-	-	S	-	-	-	Putative ABC-transporter type IV
DGNHLHCD_00701	0.0	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DGNHLHCD_00702	7.12e-251	-	-	-	L	-	-	-	Tetratricopeptide repeat
DGNHLHCD_00703	8.23e-247	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
DGNHLHCD_00705	3.26e-175	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
DGNHLHCD_00706	4.57e-143	-	-	-	-	-	-	-	-
DGNHLHCD_00707	5.24e-150	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
DGNHLHCD_00708	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
DGNHLHCD_00709	2.9e-231	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DGNHLHCD_00710	1.45e-232	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
DGNHLHCD_00711	1.06e-122	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
DGNHLHCD_00712	3.57e-158	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
DGNHLHCD_00713	6.98e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
DGNHLHCD_00714	1.09e-227	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DGNHLHCD_00715	3.09e-161	-	-	-	S	-	-	-	ABC-2 family transporter protein
DGNHLHCD_00716	4.6e-158	-	-	-	S	-	-	-	ABC-2 family transporter protein
DGNHLHCD_00717	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
DGNHLHCD_00718	5.92e-299	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DGNHLHCD_00719	2.36e-18	-	-	-	-	-	-	-	-
DGNHLHCD_00720	8.34e-89	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DGNHLHCD_00721	4.45e-109	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DGNHLHCD_00722	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
DGNHLHCD_00723	4.31e-166	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
DGNHLHCD_00724	1.66e-130	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
DGNHLHCD_00725	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
DGNHLHCD_00726	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
DGNHLHCD_00727	2.22e-232	-	-	-	S	-	-	-	Protein of unknown function (DUF559)
DGNHLHCD_00728	1.1e-254	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DGNHLHCD_00729	7.18e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DGNHLHCD_00730	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
DGNHLHCD_00731	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
DGNHLHCD_00732	3.66e-98	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
DGNHLHCD_00733	1.05e-251	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
DGNHLHCD_00734	3.43e-79	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DGNHLHCD_00735	2.51e-210	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DGNHLHCD_00736	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DGNHLHCD_00737	2.17e-253	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
DGNHLHCD_00738	0.0	-	3.2.1.8, 3.5.1.104	-	G	ko:K01181,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
DGNHLHCD_00739	1.42e-74	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
DGNHLHCD_00741	7.82e-65	-	-	-	E	-	-	-	IrrE N-terminal-like domain
DGNHLHCD_00742	4.81e-84	-	-	-	-	-	-	-	-
DGNHLHCD_00743	4.37e-80	-	-	-	-	-	-	-	-
DGNHLHCD_00745	3.76e-163	-	-	-	S	-	-	-	Domain of unknown function (DUF4417)
DGNHLHCD_00746	5.24e-57	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
DGNHLHCD_00747	4.24e-166	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
DGNHLHCD_00749	3.8e-135	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DGNHLHCD_00750	1.01e-150	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DGNHLHCD_00751	1.63e-302	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
DGNHLHCD_00752	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
DGNHLHCD_00753	0.0	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
DGNHLHCD_00754	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
DGNHLHCD_00755	6.09e-152	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
DGNHLHCD_00756	0.0	-	-	-	T	-	-	-	Histidine kinase
DGNHLHCD_00757	2.17e-151	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
DGNHLHCD_00758	8.71e-176	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
DGNHLHCD_00759	1.01e-214	-	-	-	EG	-	-	-	EamA-like transporter family
DGNHLHCD_00760	1.16e-155	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
DGNHLHCD_00761	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DGNHLHCD_00762	2.54e-235	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DGNHLHCD_00763	3.51e-174	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
DGNHLHCD_00764	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
DGNHLHCD_00765	3.39e-304	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
DGNHLHCD_00766	9.04e-231	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
DGNHLHCD_00767	1.5e-197	-	-	-	-	-	-	-	-
DGNHLHCD_00768	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
DGNHLHCD_00769	2.19e-223	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DGNHLHCD_00771	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
DGNHLHCD_00772	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
DGNHLHCD_00773	6.04e-144	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
DGNHLHCD_00774	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
DGNHLHCD_00775	3.99e-186	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
DGNHLHCD_00776	1.12e-109	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DGNHLHCD_00777	2.67e-296	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
DGNHLHCD_00778	1.7e-185	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
DGNHLHCD_00779	3.04e-13	-	-	-	S	-	-	-	Unextendable partial coding region
DGNHLHCD_00780	9.17e-201	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Phosphotransferase enzyme family
DGNHLHCD_00781	2.45e-61	-	-	-	-	-	-	-	-
DGNHLHCD_00782	3.27e-183	nfrA	-	-	C	-	-	-	Nitroreductase family
DGNHLHCD_00783	2.15e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
DGNHLHCD_00784	4.33e-179	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
DGNHLHCD_00786	9.58e-244	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
DGNHLHCD_00787	0.0	strK	3.1.3.1, 3.1.3.39	-	P	ko:K01077,ko:K04342	ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
DGNHLHCD_00788	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
DGNHLHCD_00789	1.52e-89	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DGNHLHCD_00790	2.72e-236	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
DGNHLHCD_00791	9.12e-112	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
DGNHLHCD_00792	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
DGNHLHCD_00795	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
DGNHLHCD_00796	0.0	-	-	-	-	-	-	-	-
DGNHLHCD_00797	1.05e-85	-	-	-	S	-	-	-	Zincin-like metallopeptidase
DGNHLHCD_00798	2.33e-200	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
DGNHLHCD_00799	2.3e-168	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
DGNHLHCD_00800	7.56e-92	umuD	-	-	KT	ko:K03503	-	ko00000,ko01000,ko01002,ko03400	Peptidase S24-like
DGNHLHCD_00801	1.69e-258	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
DGNHLHCD_00802	9.32e-164	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
DGNHLHCD_00803	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DGNHLHCD_00804	1.99e-131	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
DGNHLHCD_00805	3.12e-109	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
DGNHLHCD_00806	8.76e-177	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
DGNHLHCD_00807	1.15e-209	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DGNHLHCD_00808	1.97e-230	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
DGNHLHCD_00809	2.97e-211	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DGNHLHCD_00810	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
DGNHLHCD_00811	4.53e-139	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DGNHLHCD_00813	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
DGNHLHCD_00814	1.3e-152	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
DGNHLHCD_00815	1.05e-185	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
DGNHLHCD_00816	1.93e-239	-	-	-	S	-	-	-	Conserved hypothetical protein 698
DGNHLHCD_00817	6.44e-79	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
DGNHLHCD_00818	1.02e-127	-	-	-	G	-	-	-	Phosphoglycerate mutase family
DGNHLHCD_00819	7.88e-304	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
DGNHLHCD_00820	1.24e-96	-	-	-	K	-	-	-	AraC-like ligand binding domain
DGNHLHCD_00822	8.2e-68	-	-	-	IQ	-	-	-	oxidoreductase activity
DGNHLHCD_00823	8.87e-174	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
DGNHLHCD_00824	2.89e-174	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DGNHLHCD_00825	9.14e-205	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DGNHLHCD_00826	1.51e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DGNHLHCD_00827	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
DGNHLHCD_00828	1.23e-133	-	-	-	-	-	-	-	-
DGNHLHCD_00829	4.51e-261	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DGNHLHCD_00830	3.67e-275	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DGNHLHCD_00831	4.12e-227	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
DGNHLHCD_00832	1.69e-314	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
DGNHLHCD_00833	1.69e-232	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DGNHLHCD_00834	1.29e-112	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
DGNHLHCD_00835	5.96e-304	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
DGNHLHCD_00836	8.96e-15	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
DGNHLHCD_00837	3.54e-181	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
DGNHLHCD_00838	3.75e-119	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
DGNHLHCD_00839	8.44e-97	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
DGNHLHCD_00840	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DGNHLHCD_00841	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
DGNHLHCD_00842	1.4e-290	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
DGNHLHCD_00846	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
DGNHLHCD_00847	2.83e-236	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
DGNHLHCD_00848	1.49e-251	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
DGNHLHCD_00849	7.13e-87	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
DGNHLHCD_00850	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
DGNHLHCD_00851	1.23e-171	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
DGNHLHCD_00852	7.36e-227	-	-	-	-	-	-	-	-
DGNHLHCD_00853	8.25e-53	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
DGNHLHCD_00854	4.94e-84	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DGNHLHCD_00855	1.21e-36	-	-	-	-	-	-	-	-
DGNHLHCD_00856	1.49e-58	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
DGNHLHCD_00857	7.36e-106	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
DGNHLHCD_00858	2.11e-185	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DGNHLHCD_00859	1.21e-33	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
DGNHLHCD_00860	9.72e-49	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
DGNHLHCD_00861	8.15e-138	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
DGNHLHCD_00862	5.18e-228	-	-	-	S	-	-	-	Protein of unknown function DUF58
DGNHLHCD_00863	5.1e-121	-	-	-	-	-	-	-	-
DGNHLHCD_00864	7.9e-247	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
DGNHLHCD_00866	1.23e-137	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DGNHLHCD_00867	2.62e-261	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DGNHLHCD_00868	4.8e-128	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
DGNHLHCD_00869	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DGNHLHCD_00870	2.74e-207	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
DGNHLHCD_00872	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
DGNHLHCD_00873	7.76e-234	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
DGNHLHCD_00874	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DGNHLHCD_00875	3.99e-231	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
DGNHLHCD_00876	1.77e-200	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
DGNHLHCD_00877	2.89e-229	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DGNHLHCD_00878	1.75e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DGNHLHCD_00879	1.83e-33	-	-	-	K	-	-	-	MerR family regulatory protein
DGNHLHCD_00880	3.48e-245	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
DGNHLHCD_00881	5.22e-211	-	-	-	-	-	-	-	-
DGNHLHCD_00882	3.02e-26	-	-	-	KLT	-	-	-	Protein tyrosine kinase
DGNHLHCD_00883	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DGNHLHCD_00884	8.03e-311	-	-	-	V	-	-	-	MatE
DGNHLHCD_00885	6.88e-169	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
DGNHLHCD_00886	2.4e-170	-	-	-	L	ko:K07457	-	ko00000	endonuclease III
DGNHLHCD_00887	1.77e-120	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
DGNHLHCD_00888	6.55e-226	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
DGNHLHCD_00889	2.58e-89	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
DGNHLHCD_00890	2.42e-285	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA N-terminal domain
DGNHLHCD_00891	1.17e-54	-	-	-	K	-	-	-	Helix-turn-helix
DGNHLHCD_00892	6.95e-63	tam	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
DGNHLHCD_00893	1.95e-23	-	-	-	-	-	-	-	-
DGNHLHCD_00894	3.35e-131	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DGNHLHCD_00895	3.77e-118	-	-	-	T	-	-	-	Domain of unknown function (DUF4234)
DGNHLHCD_00896	1.23e-221	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
DGNHLHCD_00897	9.11e-153	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
DGNHLHCD_00898	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DGNHLHCD_00900	7.28e-208	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DGNHLHCD_00901	9.25e-82	-	-	-	K	-	-	-	Protein of unknown function, DUF488
DGNHLHCD_00902	3.32e-155	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
DGNHLHCD_00903	1.12e-126	-	-	-	K	-	-	-	FR47-like protein
DGNHLHCD_00904	1.9e-74	-	-	-	K	-	-	-	Transcriptional regulator
DGNHLHCD_00905	6.07e-130	-	-	-	F	-	-	-	Hydrolase of X-linked nucleoside diphosphate N terminal
DGNHLHCD_00907	6.93e-236	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
DGNHLHCD_00908	8.68e-12	-	-	-	L	-	-	-	Transposase and inactivated derivatives
DGNHLHCD_00909	1.34e-168	-	-	-	S	-	-	-	SOS response associated peptidase (SRAP)
DGNHLHCD_00910	1.35e-56	-	-	-	-	-	-	-	-
DGNHLHCD_00912	1.6e-104	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DGNHLHCD_00913	2.79e-226	-	-	-	M	-	-	-	heme binding
DGNHLHCD_00914	3.19e-38	-	-	-	EGP	ko:K03446,ko:K03466,ko:K03762,ko:K08217	-	br01600,ko00000,ko00002,ko01504,ko02000,ko03036	Major facilitator Superfamily
DGNHLHCD_00915	5.48e-127	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
DGNHLHCD_00917	2.07e-202	-	-	-	-	-	-	-	-
DGNHLHCD_00918	2.67e-124	-	-	-	S	-	-	-	Putative ABC-transporter type IV
DGNHLHCD_00919	9.94e-142	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
DGNHLHCD_00920	1.6e-246	-	-	-	V	-	-	-	VanZ like family
DGNHLHCD_00921	7.39e-187	-	-	-	KT	-	-	-	RESPONSE REGULATOR receiver
DGNHLHCD_00922	9.59e-92	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
DGNHLHCD_00923	3.59e-187	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
DGNHLHCD_00924	6.92e-171	-	-	-	C	-	-	-	Putative TM nitroreductase
DGNHLHCD_00927	5.13e-61	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DGNHLHCD_00928	5.06e-115	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DGNHLHCD_00929	8.54e-222	xynB2	1.1.1.169	-	E	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	lipolytic protein G-D-S-L family
DGNHLHCD_00930	0.0	-	-	-	G	-	-	-	BNR repeat-like domain
DGNHLHCD_00932	1.92e-302	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
DGNHLHCD_00934	7.39e-219	-	-	-	S	-	-	-	Protein conserved in bacteria
DGNHLHCD_00935	1.29e-189	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DGNHLHCD_00936	6.61e-234	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
DGNHLHCD_00937	8.51e-219	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
DGNHLHCD_00938	2.83e-261	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
DGNHLHCD_00939	1.28e-163	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
DGNHLHCD_00940	4.13e-90	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
DGNHLHCD_00942	7.68e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DGNHLHCD_00943	3.6e-305	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DGNHLHCD_00944	4.37e-141	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
DGNHLHCD_00945	1.75e-309	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DGNHLHCD_00946	6.38e-121	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DGNHLHCD_00947	4.69e-237	-	-	-	L	-	-	-	Excalibur calcium-binding domain
DGNHLHCD_00948	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
DGNHLHCD_00949	2.51e-120	-	-	-	D	-	-	-	nuclear chromosome segregation
DGNHLHCD_00950	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
DGNHLHCD_00951	9.48e-83	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
DGNHLHCD_00952	6.15e-127	-	-	-	S	-	-	-	GtrA-like protein
DGNHLHCD_00953	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DGNHLHCD_00954	9.49e-163	-	-	-	G	-	-	-	Phosphoglycerate mutase family
DGNHLHCD_00955	2.18e-196	-	-	-	-	-	-	-	-
DGNHLHCD_00956	4.1e-178	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
DGNHLHCD_00957	6.14e-259	-	-	-	P	-	-	-	NMT1/THI5 like
DGNHLHCD_00958	1.65e-159	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
DGNHLHCD_00960	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DGNHLHCD_00961	8.37e-124	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
DGNHLHCD_00962	2.31e-56	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
DGNHLHCD_00965	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
DGNHLHCD_00966	1.59e-179	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
DGNHLHCD_00967	8.57e-129	nnrE	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
DGNHLHCD_00968	4.51e-44	-	-	-	K	-	-	-	DNA-binding transcription factor activity
DGNHLHCD_00969	1.64e-90	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DGNHLHCD_00970	9.82e-45	-	-	-	-	-	-	-	-
DGNHLHCD_00971	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
DGNHLHCD_00972	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DGNHLHCD_00973	1.21e-244	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
DGNHLHCD_00974	5.35e-307	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
DGNHLHCD_00975	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
DGNHLHCD_00976	0.0	-	-	-	S	-	-	-	Putative esterase
DGNHLHCD_00977	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
DGNHLHCD_00979	1.64e-209	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
DGNHLHCD_00980	2.69e-180	-	-	-	S	-	-	-	cobalamin synthesis protein
DGNHLHCD_00981	1.79e-61	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
DGNHLHCD_00982	6.17e-192	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
DGNHLHCD_00983	2.65e-194	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
DGNHLHCD_00984	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
DGNHLHCD_00985	1.15e-155	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
DGNHLHCD_00986	4.45e-218	-	-	-	-	-	-	-	-
DGNHLHCD_00987	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DGNHLHCD_00988	2.54e-230	-	-	-	I	-	-	-	PAP2 superfamily
DGNHLHCD_00989	5.36e-47	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
DGNHLHCD_00990	0.0	-	-	-	L	-	-	-	PIF1-like helicase
DGNHLHCD_00991	1.58e-202	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DGNHLHCD_00992	1.91e-156	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DGNHLHCD_00993	7.8e-142	-	-	-	KT	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
DGNHLHCD_00994	4.44e-118	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
DGNHLHCD_00996	6.39e-173	-	-	-	L	-	-	-	Phage integrase family
DGNHLHCD_00997	9.85e-140	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
DGNHLHCD_00998	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
DGNHLHCD_00999	1.39e-296	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DGNHLHCD_01000	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
DGNHLHCD_01001	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1846)
DGNHLHCD_01002	6.9e-158	-	-	-	-	-	-	-	-
DGNHLHCD_01004	8.37e-145	-	-	-	S	-	-	-	Protein of unknown function (DUF1294)
DGNHLHCD_01005	1.46e-37	-	-	-	-	-	-	-	-
DGNHLHCD_01008	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
DGNHLHCD_01009	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
DGNHLHCD_01010	1.01e-137	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
DGNHLHCD_01011	2.47e-153	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
DGNHLHCD_01012	6.03e-96	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
DGNHLHCD_01013	3.36e-306	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
DGNHLHCD_01014	8.46e-242	-	-	-	EG	-	-	-	EamA-like transporter family
DGNHLHCD_01015	2.68e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
DGNHLHCD_01016	5.11e-176	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
DGNHLHCD_01017	0.0	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
DGNHLHCD_01018	1.49e-54	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DGNHLHCD_01019	7.28e-101	ulaC	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DGNHLHCD_01020	2.43e-242	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
DGNHLHCD_01022	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
DGNHLHCD_01025	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	arabinose metabolic process
DGNHLHCD_01026	9.15e-79	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DGNHLHCD_01027	8e-163	gntR	-	-	K	-	-	-	FCD
DGNHLHCD_01028	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
DGNHLHCD_01032	1.36e-19	-	-	-	K	-	-	-	Helix-turn-helix domain
DGNHLHCD_01033	2.73e-19	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
DGNHLHCD_01034	2.87e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF2442)
DGNHLHCD_01035	9.05e-12	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
DGNHLHCD_01036	4.38e-289	-	-	-	I	-	-	-	Serine aminopeptidase, S33
DGNHLHCD_01037	9.32e-240	-	-	-	K	-	-	-	Periplasmic binding protein domain
DGNHLHCD_01038	1.24e-239	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
DGNHLHCD_01041	6.81e-103	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
DGNHLHCD_01042	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DGNHLHCD_01043	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DGNHLHCD_01044	4.55e-124	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
DGNHLHCD_01045	4.6e-307	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DGNHLHCD_01046	1.15e-259	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DGNHLHCD_01047	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DGNHLHCD_01048	3.88e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
DGNHLHCD_01049	2.11e-227	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
DGNHLHCD_01050	4.15e-120	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
DGNHLHCD_01051	2.59e-162	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
DGNHLHCD_01052	3.68e-230	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
DGNHLHCD_01053	1.33e-310	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
DGNHLHCD_01054	3.91e-142	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DGNHLHCD_01055	2.56e-202	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
DGNHLHCD_01056	4.15e-171	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
DGNHLHCD_01057	4.56e-142	-	-	-	-	-	-	-	-
DGNHLHCD_01058	4.2e-242	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DGNHLHCD_01059	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DGNHLHCD_01060	3.68e-152	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DGNHLHCD_01062	1.2e-113	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
DGNHLHCD_01063	7.71e-276	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DGNHLHCD_01064	3.38e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
DGNHLHCD_01065	1.03e-105	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DGNHLHCD_01066	1.14e-124	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
DGNHLHCD_01067	4.16e-159	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DGNHLHCD_01068	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
DGNHLHCD_01069	1.43e-214	-	-	-	M	-	-	-	domain, Protein
DGNHLHCD_01070	4.33e-162	-	-	-	-	-	-	-	-
DGNHLHCD_01071	4.32e-148	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DGNHLHCD_01072	1.81e-18	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
DGNHLHCD_01073	4.3e-42	-	-	-	S	-	-	-	DUF218 domain
DGNHLHCD_01074	5.12e-77	-	-	-	S	-	-	-	DUF218 domain
DGNHLHCD_01076	9.14e-146	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
DGNHLHCD_01077	7.23e-202	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DGNHLHCD_01078	3.03e-21	-	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	Major facilitator Superfamily
DGNHLHCD_01079	0.0	-	-	-	S	-	-	-	ATPases associated with a variety of cellular activities
DGNHLHCD_01080	3.68e-229	glkA	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
DGNHLHCD_01082	1.73e-97	-	-	-	EGP	-	-	-	Major facilitator superfamily
DGNHLHCD_01083	7.9e-48	-	-	-	C	-	-	-	Aldo/keto reductase family
DGNHLHCD_01084	0.0	-	2.5.1.49	-	H	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
DGNHLHCD_01085	1.27e-271	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
DGNHLHCD_01086	1.12e-77	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DGNHLHCD_01087	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
DGNHLHCD_01088	0.0	-	-	-	I	-	-	-	PAP2 superfamily
DGNHLHCD_01089	2.92e-171	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
DGNHLHCD_01090	0.0	-	-	-	T	-	-	-	Histidine kinase
DGNHLHCD_01091	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
DGNHLHCD_01092	4.99e-182	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DGNHLHCD_01093	3.08e-215	iaaA	3.4.19.5	-	E	ko:K13051	-	ko00000,ko01000,ko01002	Asparaginase
DGNHLHCD_01094	1.1e-188	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
DGNHLHCD_01095	2.43e-240	acoA	1.2.4.1	-	C	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
DGNHLHCD_01096	1.29e-234	acoB	1.2.4.1, 1.2.4.4	-	C	ko:K00162,ko:K11381,ko:K21417	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
DGNHLHCD_01097	2.72e-261	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DGNHLHCD_01098	9.77e-123	-	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DGNHLHCD_01099	4.42e-204	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K10907,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
DGNHLHCD_01101	1.97e-198	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
DGNHLHCD_01102	3.56e-198	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
DGNHLHCD_01103	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
DGNHLHCD_01104	6.4e-05	-	-	-	O	ko:K18546	-	ko00000,ko01000,ko01002	Peptidase s1 and s6 chymotrypsin hap
DGNHLHCD_01105	6.53e-95	-	-	-	M	-	-	-	Spy0128-like isopeptide containing domain
DGNHLHCD_01106	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
DGNHLHCD_01107	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DGNHLHCD_01108	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
DGNHLHCD_01109	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DGNHLHCD_01110	2.91e-230	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
DGNHLHCD_01111	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
DGNHLHCD_01112	3.31e-140	aspA	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
DGNHLHCD_01114	5.44e-161	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
DGNHLHCD_01115	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DGNHLHCD_01116	2.19e-220	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
DGNHLHCD_01117	3.4e-156	-	-	-	L	-	-	-	NUDIX domain
DGNHLHCD_01118	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
DGNHLHCD_01119	2.42e-278	-	-	-	-	-	-	-	-
DGNHLHCD_01120	0.0	-	-	-	-	-	-	-	-
DGNHLHCD_01121	1.95e-185	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
DGNHLHCD_01122	1.83e-167	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DGNHLHCD_01123	1.39e-66	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
DGNHLHCD_01124	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DGNHLHCD_01125	2.73e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DGNHLHCD_01126	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DGNHLHCD_01127	4.65e-191	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DGNHLHCD_01128	7.5e-98	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DGNHLHCD_01129	1.21e-40	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DGNHLHCD_01131	3.54e-188	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
DGNHLHCD_01132	2.41e-264	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DGNHLHCD_01134	3.59e-47	-	-	-	-	-	-	-	-
DGNHLHCD_01135	4.17e-161	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
DGNHLHCD_01137	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
DGNHLHCD_01138	1.13e-118	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DGNHLHCD_01140	9.17e-131	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
DGNHLHCD_01141	5.6e-170	-	-	-	-	-	-	-	-
DGNHLHCD_01142	7.59e-173	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
DGNHLHCD_01143	8.16e-154	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DGNHLHCD_01144	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
DGNHLHCD_01145	2.07e-18	-	-	-	-	-	-	-	-
DGNHLHCD_01146	1.11e-262	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DGNHLHCD_01147	2.02e-306	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
DGNHLHCD_01148	2.48e-202	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
DGNHLHCD_01149	2.15e-284	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
DGNHLHCD_01150	1.38e-103	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DGNHLHCD_01151	2.2e-183	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
DGNHLHCD_01152	8.4e-27	-	-	-	-	-	-	-	-
DGNHLHCD_01153	8.09e-31	-	-	-	-	-	-	-	-
DGNHLHCD_01155	1.1e-310	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
DGNHLHCD_01156	4.17e-280	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
DGNHLHCD_01157	3.99e-298	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DGNHLHCD_01160	1.44e-182	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
DGNHLHCD_01161	4.19e-197	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DGNHLHCD_01162	1.25e-168	-	-	-	S	-	-	-	Domain of unknown function (DUF1963)
DGNHLHCD_01163	4.37e-96	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
DGNHLHCD_01164	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DGNHLHCD_01165	4.45e-242	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DGNHLHCD_01166	3.27e-94	megL	4.4.1.11	-	E	ko:K01761	ko00270,ko00450,map00270,map00450	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
DGNHLHCD_01167	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
DGNHLHCD_01168	2.43e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
DGNHLHCD_01169	9.98e-147	xylR	-	-	K	ko:K02529	-	ko00000,ko03000	purine nucleotide biosynthetic process
DGNHLHCD_01170	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
DGNHLHCD_01171	8.32e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DGNHLHCD_01172	3.14e-155	-	-	-	-	-	-	-	-
DGNHLHCD_01173	1.15e-179	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
DGNHLHCD_01175	6.64e-296	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
DGNHLHCD_01176	6.56e-252	-	-	-	-	-	-	-	-
DGNHLHCD_01177	3.43e-194	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
DGNHLHCD_01178	1.46e-242	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
DGNHLHCD_01179	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
DGNHLHCD_01180	5.94e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
DGNHLHCD_01181	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DGNHLHCD_01182	4.1e-180	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
DGNHLHCD_01183	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
DGNHLHCD_01184	9.42e-25	-	-	-	-	-	-	-	-
DGNHLHCD_01186	8.73e-21	-	-	-	-	-	-	-	-
DGNHLHCD_01190	6.65e-18	-	-	-	L	-	-	-	Transposase
DGNHLHCD_01191	1.2e-131	-	-	-	K	-	-	-	cell envelope-related transcriptional attenuator
DGNHLHCD_01193	0.0	-	-	-	-	-	-	-	-
DGNHLHCD_01194	1.44e-229	-	-	-	S	ko:K21688	-	ko00000	G5
DGNHLHCD_01195	1.05e-77	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
DGNHLHCD_01196	8.16e-154	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
DGNHLHCD_01197	1.46e-205	-	-	-	I	-	-	-	Alpha/beta hydrolase family
DGNHLHCD_01198	4.52e-263	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
DGNHLHCD_01199	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
DGNHLHCD_01200	2.17e-93	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
DGNHLHCD_01201	0.0	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
DGNHLHCD_01204	2.24e-103	-	-	-	-	-	-	-	-
DGNHLHCD_01205	6.41e-42	-	-	-	Q	-	-	-	phosphatase activity
DGNHLHCD_01206	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
DGNHLHCD_01207	1.29e-66	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
DGNHLHCD_01208	5.95e-65	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
DGNHLHCD_01209	0.0	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DGNHLHCD_01210	1.13e-86	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
DGNHLHCD_01211	1.5e-167	-	-	-	K	ko:K03489,ko:K03710	-	ko00000,ko03000	UTRA
DGNHLHCD_01212	2.31e-102	-	-	-	S	-	-	-	FMN_bind
DGNHLHCD_01213	7.76e-191	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DGNHLHCD_01214	1.9e-280	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
DGNHLHCD_01215	3.23e-289	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
DGNHLHCD_01216	8.71e-296	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
DGNHLHCD_01217	2.38e-150	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
DGNHLHCD_01218	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
DGNHLHCD_01219	8.33e-31	-	-	-	G	-	-	-	MFS/sugar transport protein
DGNHLHCD_01220	1.23e-257	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DGNHLHCD_01221	6.49e-115	-	-	-	S	-	-	-	Fic/DOC family
DGNHLHCD_01222	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DGNHLHCD_01223	1.47e-50	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
DGNHLHCD_01224	8.04e-257	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
DGNHLHCD_01225	3.5e-271	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
DGNHLHCD_01226	2.08e-158	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DGNHLHCD_01227	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DGNHLHCD_01228	4.39e-249	-	-	-	I	-	-	-	PAP2 superfamily
DGNHLHCD_01229	0.0	-	-	-	M	-	-	-	PA domain
DGNHLHCD_01230	5.96e-178	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
DGNHLHCD_01231	1.27e-295	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
DGNHLHCD_01232	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
DGNHLHCD_01233	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DGNHLHCD_01234	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
DGNHLHCD_01235	8.35e-24	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
DGNHLHCD_01236	0.0	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
DGNHLHCD_01237	1.77e-148	-	-	-	-	-	-	-	-
DGNHLHCD_01238	7.59e-269	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DGNHLHCD_01239	2.36e-125	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
DGNHLHCD_01240	1.31e-47	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
DGNHLHCD_01241	4.41e-309	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
DGNHLHCD_01242	5.93e-196	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DGNHLHCD_01243	2.9e-276	-	-	-	GK	-	-	-	ROK family
DGNHLHCD_01244	3.42e-169	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
DGNHLHCD_01245	1.25e-284	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
DGNHLHCD_01246	2.87e-217	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
DGNHLHCD_01247	6.45e-302	-	-	-	G	-	-	-	Major Facilitator Superfamily
DGNHLHCD_01248	2.22e-108	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DGNHLHCD_01251	7.49e-235	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
DGNHLHCD_01252	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
DGNHLHCD_01253	1.1e-276	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DGNHLHCD_01254	2.71e-298	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
DGNHLHCD_01255	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DGNHLHCD_01256	8.76e-261	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DGNHLHCD_01257	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DGNHLHCD_01258	2.48e-231	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DGNHLHCD_01259	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
DGNHLHCD_01260	2.38e-41	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DGNHLHCD_01263	1.43e-122	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DGNHLHCD_01264	1.41e-285	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
DGNHLHCD_01265	3.9e-131	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DGNHLHCD_01266	3.73e-72	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
DGNHLHCD_01267	6.91e-259	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DGNHLHCD_01268	3.03e-134	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DGNHLHCD_01269	7.56e-129	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DGNHLHCD_01270	2.79e-176	yebC	-	-	K	-	-	-	transcriptional regulatory protein
DGNHLHCD_01271	4.5e-217	-	3.2.1.52	GH20	M	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
DGNHLHCD_01272	0.0	-	3.2.1.52	GH20	M	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
DGNHLHCD_01273	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DGNHLHCD_01274	0.0	-	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DGNHLHCD_01275	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
DGNHLHCD_01276	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
DGNHLHCD_01277	1.1e-298	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
DGNHLHCD_01278	2.73e-240	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
DGNHLHCD_01279	2.45e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
DGNHLHCD_01280	1.75e-110	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
DGNHLHCD_01281	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DGNHLHCD_01283	1.91e-82	intA	-	-	L	-	-	-	Phage integrase family
DGNHLHCD_01286	1.87e-66	-	-	-	S	-	-	-	Eco47II restriction endonuclease
DGNHLHCD_01287	4.83e-202	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
DGNHLHCD_01288	6.49e-28	tam	2.1.1.144	-	S	ko:K00598	-	ko00000,ko01000	Methyltransferase domain
DGNHLHCD_01289	2.05e-125	tam	2.1.1.144	-	S	ko:K00598	-	ko00000,ko01000	Methyltransferase domain
DGNHLHCD_01290	1.7e-298	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DGNHLHCD_01291	1.77e-72	-	-	-	L	-	-	-	RelB antitoxin
DGNHLHCD_01293	8.3e-171	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DGNHLHCD_01294	1.82e-310	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
DGNHLHCD_01296	1.06e-60	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
DGNHLHCD_01297	0.0	-	-	-	-	-	-	-	-
DGNHLHCD_01301	2.89e-199	-	-	-	S	-	-	-	PAC2 family
DGNHLHCD_01302	2.74e-214	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
DGNHLHCD_01303	4.73e-203	-	-	-	G	-	-	-	Fructosamine kinase
DGNHLHCD_01304	6.31e-273	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DGNHLHCD_01305	9.83e-281	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DGNHLHCD_01306	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
DGNHLHCD_01307	4.49e-258	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DGNHLHCD_01308	1.27e-181	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
DGNHLHCD_01309	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
DGNHLHCD_01310	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
DGNHLHCD_01311	1.06e-260	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
DGNHLHCD_01312	7.44e-151	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
DGNHLHCD_01313	1.11e-79	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
DGNHLHCD_01314	9.44e-234	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DGNHLHCD_01315	3.2e-244	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DGNHLHCD_01316	1.85e-48	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
DGNHLHCD_01319	1.04e-56	-	-	-	K	ko:K13633	-	ko00000,ko03000	helix_turn_helix, arabinose operon control protein
DGNHLHCD_01320	1.18e-85	-	-	-	K	ko:K13633	-	ko00000,ko03000	helix_turn_helix, arabinose operon control protein
DGNHLHCD_01321	1.1e-209	-	-	-	G	ko:K05340	-	ko00000,ko02000	Sugar transport protein
DGNHLHCD_01322	9.51e-240	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
DGNHLHCD_01323	3.01e-200	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	Mycolic acid cyclopropane synthetase
DGNHLHCD_01324	1.26e-122	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
DGNHLHCD_01325	4.53e-205	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
DGNHLHCD_01326	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DGNHLHCD_01327	7.71e-314	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
DGNHLHCD_01328	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DGNHLHCD_01329	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
DGNHLHCD_01330	2.63e-121	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DGNHLHCD_01331	4.63e-38	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
DGNHLHCD_01332	1.27e-118	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DGNHLHCD_01333	1.12e-283	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
DGNHLHCD_01334	2.87e-102	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
DGNHLHCD_01335	6.2e-145	-	-	-	S	-	-	-	Domain of unknown function (DUF4854)
DGNHLHCD_01336	5.72e-199	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
DGNHLHCD_01338	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DGNHLHCD_01339	2.97e-169	-	-	-	M	-	-	-	Mechanosensitive ion channel
DGNHLHCD_01340	1.51e-153	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DGNHLHCD_01341	3.21e-305	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
DGNHLHCD_01342	1.61e-293	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
DGNHLHCD_01343	2.12e-111	-	-	-	-	-	-	-	-
DGNHLHCD_01345	2.76e-55	-	-	-	K	-	-	-	Transcriptional regulator
DGNHLHCD_01346	8.89e-31	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
DGNHLHCD_01347	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
DGNHLHCD_01348	0.0	-	-	-	M	-	-	-	Conserved repeat domain
DGNHLHCD_01349	3.18e-160	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
DGNHLHCD_01350	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
DGNHLHCD_01351	6.94e-146	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
DGNHLHCD_01352	1.32e-213	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DGNHLHCD_01353	1.27e-217	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DGNHLHCD_01354	1.14e-23	rpfB	-	-	S	ko:K21688	-	ko00000	G5
DGNHLHCD_01356	0.0	-	-	-	-	-	-	-	-
DGNHLHCD_01357	5.15e-228	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
DGNHLHCD_01358	0.0	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
DGNHLHCD_01359	6.67e-86	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
DGNHLHCD_01360	6.75e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF2442)
DGNHLHCD_01361	4.22e-68	-	-	-	-	-	-	-	-
DGNHLHCD_01362	1.92e-87	-	-	-	-	-	-	-	-
DGNHLHCD_01363	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
DGNHLHCD_01364	2.72e-108	-	-	-	-	-	-	-	-
DGNHLHCD_01365	3.35e-87	-	-	-	-	-	-	-	-
DGNHLHCD_01366	7.9e-74	-	-	-	-	-	-	-	-
DGNHLHCD_01367	8.31e-292	-	-	-	S	-	-	-	HipA-like C-terminal domain
DGNHLHCD_01368	1.13e-271	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
DGNHLHCD_01369	0.0	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
DGNHLHCD_01370	0.0	-	-	-	M	-	-	-	domain protein
DGNHLHCD_01371	2.45e-70	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Acylphosphatase
DGNHLHCD_01372	1.38e-187	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DGNHLHCD_01373	5.99e-237	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
DGNHLHCD_01374	3.2e-176	-	-	-	M	-	-	-	Protein of unknown function (DUF3152)
DGNHLHCD_01375	3.99e-176	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
DGNHLHCD_01377	7.2e-95	-	-	-	E	-	-	-	Domain of unknown function (DUF5011)
DGNHLHCD_01378	2.59e-41	-	-	-	S	-	-	-	Parallel beta-helix repeats
DGNHLHCD_01379	2.34e-92	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
DGNHLHCD_01380	1.51e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DGNHLHCD_01381	3.89e-110	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
DGNHLHCD_01382	6.47e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
DGNHLHCD_01383	2.59e-246	-	-	-	T	-	-	-	Pfam Adenylate and Guanylate cyclase catalytic domain
DGNHLHCD_01384	7.7e-169	-	-	-	-	-	-	-	-
DGNHLHCD_01385	0.0	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DGNHLHCD_01386	5.34e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DGNHLHCD_01387	0.0	-	3.2.1.97	GH101	G	ko:K17624	-	ko00000,ko01000	Glycosyl hydrolase 101 beta sandwich domain
DGNHLHCD_01388	1.73e-253	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
DGNHLHCD_01389	8.22e-278	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
DGNHLHCD_01390	1.38e-227	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
DGNHLHCD_01391	3.25e-221	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
DGNHLHCD_01392	1.16e-182	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
DGNHLHCD_01393	1.42e-43	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DGNHLHCD_01395	7.11e-295	aspC	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
DGNHLHCD_01396	1.23e-255	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DGNHLHCD_01397	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DGNHLHCD_01398	6.56e-276	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
DGNHLHCD_01399	2.12e-53	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
DGNHLHCD_01400	1.44e-62	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
DGNHLHCD_01401	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
DGNHLHCD_01402	8.12e-207	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
DGNHLHCD_01403	1.78e-179	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
DGNHLHCD_01404	2.97e-144	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DGNHLHCD_01405	3.8e-252	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DGNHLHCD_01406	2.49e-255	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
DGNHLHCD_01407	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
DGNHLHCD_01408	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
DGNHLHCD_01410	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DGNHLHCD_01411	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DGNHLHCD_01412	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DGNHLHCD_01413	6.97e-285	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
DGNHLHCD_01414	1.36e-131	-	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
DGNHLHCD_01415	0.0	-	-	-	EK	ko:K05825,ko:K18907	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko00002,ko01000,ko01504,ko03000	Alanine-glyoxylate amino-transferase
DGNHLHCD_01416	2.4e-80	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
DGNHLHCD_01417	3.56e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
DGNHLHCD_01418	3.22e-139	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DGNHLHCD_01419	3.51e-226	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
DGNHLHCD_01420	1.07e-107	-	-	-	O	-	-	-	Hsp20/alpha crystallin family
DGNHLHCD_01421	6.45e-138	-	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
DGNHLHCD_01422	2.98e-153	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
DGNHLHCD_01423	9.34e-75	-	-	-	U	ko:K06956	-	ko00000	Sodium:dicarboxylate symporter family
DGNHLHCD_01425	1.53e-173	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
DGNHLHCD_01426	4.03e-85	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
DGNHLHCD_01427	7.33e-50	-	-	-	-	-	-	-	-
DGNHLHCD_01428	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DGNHLHCD_01429	6.58e-99	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DGNHLHCD_01430	2e-250	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DGNHLHCD_01431	3.06e-68	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
DGNHLHCD_01432	1.57e-280	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DGNHLHCD_01433	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DGNHLHCD_01434	1.87e-102	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
DGNHLHCD_01435	2.14e-21	-	-	-	-	-	-	-	-
DGNHLHCD_01436	1.61e-153	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
DGNHLHCD_01437	1e-203	-	-	-	S	-	-	-	Protein conserved in bacteria
DGNHLHCD_01438	3.35e-269	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
DGNHLHCD_01439	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DGNHLHCD_01440	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
DGNHLHCD_01441	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DGNHLHCD_01442	2.81e-257	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DGNHLHCD_01443	1.28e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DGNHLHCD_01444	5.18e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
DGNHLHCD_01445	8.06e-141	-	-	-	-	-	-	-	-
DGNHLHCD_01446	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DGNHLHCD_01447	2.98e-135	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
DGNHLHCD_01448	9.97e-145	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
DGNHLHCD_01449	2.85e-302	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DGNHLHCD_01450	8.76e-124	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DGNHLHCD_01451	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DGNHLHCD_01452	9.39e-170	-	-	-	L	-	-	-	transposase activity
DGNHLHCD_01453	5.77e-137	-	-	-	L	-	-	-	PFAM Integrase catalytic
DGNHLHCD_01454	4.62e-200	-	-	-	L	-	-	-	Transposase, Mutator family
DGNHLHCD_01455	1.48e-214	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DGNHLHCD_01456	5.96e-167	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
DGNHLHCD_01457	2.18e-266	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DGNHLHCD_01458	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
DGNHLHCD_01459	0.0	-	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
DGNHLHCD_01460	5.36e-247	-	-	-	M	-	-	-	Glycosyltransferase like family 2
DGNHLHCD_01461	5.13e-103	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
DGNHLHCD_01462	1.92e-195	-	-	-	EGP	-	-	-	Transmembrane secretion effector
DGNHLHCD_01463	0.0	-	-	-	S	-	-	-	Esterase-like activity of phytase
DGNHLHCD_01464	5.83e-293	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DGNHLHCD_01465	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DGNHLHCD_01466	9.4e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DGNHLHCD_01467	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DGNHLHCD_01469	5.42e-255	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
DGNHLHCD_01470	6.83e-233	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
DGNHLHCD_01471	1.26e-145	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
DGNHLHCD_01472	5.19e-222	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DGNHLHCD_01473	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
DGNHLHCD_01474	2.11e-53	-	-	-	-	-	-	-	-
DGNHLHCD_01475	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DGNHLHCD_01476	6.96e-286	-	-	-	S	-	-	-	Peptidase dimerisation domain
DGNHLHCD_01477	6.05e-121	-	-	-	P	-	-	-	ABC-type metal ion transport system permease component
DGNHLHCD_01478	2.76e-212	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DGNHLHCD_01479	3.42e-134	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DGNHLHCD_01480	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
DGNHLHCD_01481	3.29e-302	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DGNHLHCD_01484	2.73e-162	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
DGNHLHCD_01485	5.59e-78	yccF	-	-	S	-	-	-	Inner membrane component domain
DGNHLHCD_01486	6.35e-201	-	-	-	J	-	-	-	Methyltransferase domain
DGNHLHCD_01487	4.93e-107	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
DGNHLHCD_01488	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
DGNHLHCD_01489	4.25e-103	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
DGNHLHCD_01491	1.1e-30	-	-	-	-	-	-	-	-
DGNHLHCD_01492	5.98e-264	-	-	-	S	-	-	-	Short C-terminal domain
DGNHLHCD_01493	1.1e-112	-	-	-	S	-	-	-	Helix-turn-helix
DGNHLHCD_01494	3.35e-84	-	-	-	S	-	-	-	Zincin-like metallopeptidase
DGNHLHCD_01495	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
DGNHLHCD_01496	3.91e-175	-	-	-	S	-	-	-	zinc-ribbon domain
DGNHLHCD_01497	1.9e-62	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
DGNHLHCD_01498	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
DGNHLHCD_01500	7.16e-258	-	-	-	K	-	-	-	WYL domain
DGNHLHCD_01501	5.5e-199	-	-	-	S	-	-	-	Aldo/keto reductase family
DGNHLHCD_01502	2.11e-221	dkgV	-	-	C	-	-	-	Aldo/keto reductase family
DGNHLHCD_01503	1.31e-26	-	-	-	S	-	-	-	Domain of unknown function (DUF4186)
DGNHLHCD_01504	1.97e-59	-	-	-	S	-	-	-	Domain of unknown function (DUF4186)
DGNHLHCD_01507	2.68e-232	-	-	-	S	-	-	-	Protein conserved in bacteria
DGNHLHCD_01508	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DGNHLHCD_01509	2.16e-284	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DGNHLHCD_01510	1.08e-145	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
DGNHLHCD_01511	5.28e-151	-	-	-	-	-	-	-	-
DGNHLHCD_01512	1.35e-156	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DGNHLHCD_01513	4.81e-167	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
DGNHLHCD_01514	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2252)
DGNHLHCD_01515	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
DGNHLHCD_01516	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
DGNHLHCD_01517	4.75e-80	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator Superfamily
DGNHLHCD_01518	3.66e-199	-	-	-	M	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
DGNHLHCD_01519	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
DGNHLHCD_01520	4.17e-156	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
DGNHLHCD_01521	4.62e-224	-	-	-	-	-	-	-	-
DGNHLHCD_01522	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DGNHLHCD_01523	1.96e-226	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
DGNHLHCD_01524	3.88e-213	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DGNHLHCD_01525	3.03e-166	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DGNHLHCD_01526	5.9e-66	-	-	-	M	-	-	-	Lysin motif
DGNHLHCD_01527	3.1e-108	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DGNHLHCD_01528	9.66e-292	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
DGNHLHCD_01529	0.0	-	-	-	L	-	-	-	DNA helicase
DGNHLHCD_01530	8.85e-118	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
DGNHLHCD_01532	5.72e-205	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
DGNHLHCD_01534	6.24e-175	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DGNHLHCD_01535	1.37e-76	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
DGNHLHCD_01536	1.49e-253	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
DGNHLHCD_01537	1.82e-130	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DGNHLHCD_01538	0.0	corC	-	-	S	-	-	-	CBS domain
DGNHLHCD_01539	5.62e-236	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DGNHLHCD_01540	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
DGNHLHCD_01541	6.9e-259	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
DGNHLHCD_01542	1.08e-58	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
DGNHLHCD_01544	8.27e-191	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
DGNHLHCD_01545	1.26e-191	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
DGNHLHCD_01546	1.09e-05	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DGNHLHCD_01547	1.23e-210	-	-	-	EG	-	-	-	EamA-like transporter family
DGNHLHCD_01548	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
DGNHLHCD_01549	1.68e-190	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
DGNHLHCD_01550	1.6e-218	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
DGNHLHCD_01551	1.52e-145	-	-	-	-	-	-	-	-
DGNHLHCD_01552	1.42e-308	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DGNHLHCD_01553	1.17e-137	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
DGNHLHCD_01554	4.14e-132	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
DGNHLHCD_01555	3.62e-306	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DGNHLHCD_01556	2.13e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
DGNHLHCD_01557	4.26e-166	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
DGNHLHCD_01558	9.91e-70	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
DGNHLHCD_01559	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
DGNHLHCD_01560	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DGNHLHCD_01561	1.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DGNHLHCD_01562	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
DGNHLHCD_01563	1.61e-274	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
DGNHLHCD_01564	3.62e-73	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
DGNHLHCD_01565	1.28e-73	-	-	-	U	-	-	-	TadE-like protein
DGNHLHCD_01566	1.13e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
DGNHLHCD_01567	2.66e-112	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
DGNHLHCD_01568	6.16e-156	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
DGNHLHCD_01569	2.7e-216	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
DGNHLHCD_01572	2.59e-201	-	-	-	O	-	-	-	Thioredoxin
DGNHLHCD_01573	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
DGNHLHCD_01574	7.97e-223	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
DGNHLHCD_01575	1.54e-269	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
DGNHLHCD_01576	2.48e-129	-	-	-	L	-	-	-	Helix-turn-helix domain
DGNHLHCD_01577	5.26e-268	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DGNHLHCD_01578	4.7e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
DGNHLHCD_01579	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
DGNHLHCD_01580	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
DGNHLHCD_01581	0.0	-	-	-	S	-	-	-	PGAP1-like protein
DGNHLHCD_01583	4.25e-106	-	-	-	-	-	-	-	-
DGNHLHCD_01584	1.53e-56	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
DGNHLHCD_01587	4.39e-209	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
DGNHLHCD_01588	5.82e-130	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DGNHLHCD_01589	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
DGNHLHCD_01591	7.59e-41	-	-	-	-	-	-	-	-
DGNHLHCD_01592	1.19e-52	-	-	-	-	-	-	-	-
DGNHLHCD_01593	0.0	-	-	-	KL	-	-	-	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DGNHLHCD_01597	1.89e-138	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
DGNHLHCD_01598	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
DGNHLHCD_01599	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
DGNHLHCD_01600	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
DGNHLHCD_01601	7.47e-123	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
DGNHLHCD_01602	2.2e-244	-	-	-	C	-	-	-	Aldo/keto reductase family
DGNHLHCD_01603	3.51e-27	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
DGNHLHCD_01604	6.22e-206	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
DGNHLHCD_01605	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
DGNHLHCD_01606	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
DGNHLHCD_01607	1.82e-176	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
DGNHLHCD_01608	1.29e-233	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DGNHLHCD_01609	3.86e-174	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
DGNHLHCD_01610	3.26e-157	-	-	-	T	-	-	-	Forkhead associated domain
DGNHLHCD_01611	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
DGNHLHCD_01612	2.87e-56	-	-	-	-	-	-	-	-
DGNHLHCD_01613	2.02e-139	-	-	-	NO	-	-	-	SAF
DGNHLHCD_01614	1.88e-51	-	-	-	S	-	-	-	Putative regulatory protein
DGNHLHCD_01615	3.43e-155	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
DGNHLHCD_01616	2.84e-190	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
DGNHLHCD_01617	6.36e-273	-	-	-	-	-	-	-	-
DGNHLHCD_01618	3.49e-63	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DGNHLHCD_01619	1.12e-166	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
DGNHLHCD_01620	9.06e-57	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
DGNHLHCD_01624	2.71e-35	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
DGNHLHCD_01625	2.6e-278	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
DGNHLHCD_01626	3.55e-81	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
DGNHLHCD_01627	8.15e-285	dapC	-	-	E	-	-	-	Aminotransferase class I and II
DGNHLHCD_01628	2.21e-305	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DGNHLHCD_01630	0.0	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
DGNHLHCD_01631	9.43e-146	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
DGNHLHCD_01632	5.92e-155	-	-	-	-	-	-	-	-
DGNHLHCD_01633	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
DGNHLHCD_01634	2.64e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DGNHLHCD_01635	1.71e-99	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
DGNHLHCD_01636	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
DGNHLHCD_01637	1.01e-296	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
DGNHLHCD_01638	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
DGNHLHCD_01639	1.94e-213	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
DGNHLHCD_01641	5.67e-135	-	-	-	S	-	-	-	YwiC-like protein
DGNHLHCD_01642	5.42e-67	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
DGNHLHCD_01643	6.65e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DGNHLHCD_01644	1.34e-154	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
DGNHLHCD_01645	2.54e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DGNHLHCD_01646	1.15e-196	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DGNHLHCD_01647	1.4e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DGNHLHCD_01648	2.21e-74	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DGNHLHCD_01649	2.73e-161	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DGNHLHCD_01650	6.64e-55	-	-	-	-	-	-	-	-
DGNHLHCD_01652	4.85e-83	treS_1	-	-	G	-	-	-	Alpha amylase, catalytic domain
DGNHLHCD_01653	5.01e-203	treS_1	-	-	G	-	-	-	Alpha amylase, catalytic domain
DGNHLHCD_01654	1.26e-100	-	-	-	S	-	-	-	Bacterial PH domain
DGNHLHCD_01655	4.04e-178	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
DGNHLHCD_01656	6.1e-89	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DGNHLHCD_01657	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DGNHLHCD_01659	6.24e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DGNHLHCD_01660	5.93e-187	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DGNHLHCD_01661	2.45e-56	-	-	-	-	-	-	-	-
DGNHLHCD_01662	4.27e-186	-	-	-	K	-	-	-	DeoR C terminal sensor domain
DGNHLHCD_01663	2.4e-251	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
DGNHLHCD_01664	5.01e-276	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
DGNHLHCD_01665	0.0	pon1	-	-	M	-	-	-	Transglycosylase
DGNHLHCD_01666	4.67e-173	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
DGNHLHCD_01667	4.93e-151	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
DGNHLHCD_01668	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DGNHLHCD_01669	2.25e-284	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DGNHLHCD_01670	9.87e-70	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DGNHLHCD_01671	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
DGNHLHCD_01672	7.42e-212	-	-	-	S	-	-	-	Protein conserved in bacteria
DGNHLHCD_01674	5.2e-185	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DGNHLHCD_01675	2.05e-177	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
DGNHLHCD_01676	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
DGNHLHCD_01677	6.39e-140	-	-	-	-	-	-	-	-
DGNHLHCD_01678	2.2e-140	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
DGNHLHCD_01679	3.01e-59	-	-	-	S	ko:K06990	-	ko00000,ko04812	Memo-like protein
DGNHLHCD_01681	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DGNHLHCD_01682	2.49e-229	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
DGNHLHCD_01683	5.14e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DGNHLHCD_01684	5.14e-291	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DGNHLHCD_01685	4.79e-95	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
DGNHLHCD_01686	2.28e-62	-	-	-	-	-	-	-	-
DGNHLHCD_01687	8.16e-142	-	-	-	S	-	-	-	TIGRFAM TIGR03943 family protein
DGNHLHCD_01688	2.4e-256	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
DGNHLHCD_01689	6.34e-33	-	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal L32p protein family
DGNHLHCD_01690	3.05e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
DGNHLHCD_01691	3.09e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
DGNHLHCD_01692	1.2e-45	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
DGNHLHCD_01693	3.84e-189	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DGNHLHCD_01694	2.62e-281	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
DGNHLHCD_01695	3.1e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
DGNHLHCD_01696	4.29e-227	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
DGNHLHCD_01697	6.65e-234	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
DGNHLHCD_01698	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DGNHLHCD_01699	8.8e-244	-	-	-	I	ko:K13663	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
DGNHLHCD_01701	4.28e-164	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
DGNHLHCD_01702	4.93e-252	-	-	-	GM	-	-	-	GDP-mannose 4,6 dehydratase
DGNHLHCD_01703	1.5e-149	-	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
DGNHLHCD_01704	1.97e-186	rfbB2	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
DGNHLHCD_01705	1.06e-125	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
DGNHLHCD_01706	2.86e-145	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DGNHLHCD_01707	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DGNHLHCD_01708	1.6e-140	-	-	-	-	-	-	-	-
DGNHLHCD_01711	1.67e-104	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DGNHLHCD_01712	8.53e-95	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
DGNHLHCD_01713	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
DGNHLHCD_01714	2.65e-127	-	-	-	-	-	-	-	-
DGNHLHCD_01716	5.06e-235	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
DGNHLHCD_01717	4.9e-105	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
DGNHLHCD_01718	1.84e-105	-	-	-	-	-	-	-	-
DGNHLHCD_01719	6.4e-123	-	-	-	L	-	-	-	Restriction endonuclease NotI
DGNHLHCD_01721	4.99e-61	-	-	-	-	-	-	-	-
DGNHLHCD_01722	7.13e-56	-	-	-	O	-	-	-	Glutaredoxin
DGNHLHCD_01723	9.99e-193	-	-	-	S	ko:K07058	-	ko00000	Virulence factor BrkB
DGNHLHCD_01724	8.29e-129	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
DGNHLHCD_01725	9.3e-53	urtE	-	-	E	ko:K11963	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DGNHLHCD_01726	8.28e-291	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DGNHLHCD_01727	4.26e-222	fmt2	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
DGNHLHCD_01728	6.09e-152	safC	-	-	S	-	-	-	O-methyltransferase
DGNHLHCD_01729	2.15e-236	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
DGNHLHCD_01730	2.23e-93	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
DGNHLHCD_01731	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
DGNHLHCD_01732	1.69e-201	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
DGNHLHCD_01733	8.77e-77	-	-	-	L	ko:K07443	-	ko00000	6-O-methylguanine DNA methyltransferase, DNA binding domain
DGNHLHCD_01734	1.71e-32	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
DGNHLHCD_01736	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DGNHLHCD_01737	1.18e-162	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
DGNHLHCD_01738	0.0	tcsS3	-	-	KT	-	-	-	PspC domain
DGNHLHCD_01739	0.0	pspC	-	-	KT	-	-	-	PspC domain
DGNHLHCD_01740	1.6e-203	-	-	-	-	-	-	-	-
DGNHLHCD_01741	9.55e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
DGNHLHCD_01742	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
DGNHLHCD_01743	5.47e-280	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
DGNHLHCD_01745	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
DGNHLHCD_01746	2.37e-223	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
DGNHLHCD_01747	3.69e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DGNHLHCD_01749	6.57e-153	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
DGNHLHCD_01750	4.1e-291	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
DGNHLHCD_01751	4.6e-53	-	-	-	-	-	-	-	-
DGNHLHCD_01752	4.22e-276	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DGNHLHCD_01753	1.1e-233	-	-	-	S	-	-	-	CHAP domain
DGNHLHCD_01754	4.74e-160	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
DGNHLHCD_01755	1.31e-244	-	-	-	T	-	-	-	Universal stress protein family
DGNHLHCD_01756	5.29e-95	-	-	-	O	-	-	-	OsmC-like protein
DGNHLHCD_01757	4.99e-223	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DGNHLHCD_01758	5.46e-165	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
DGNHLHCD_01759	9.52e-124	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
DGNHLHCD_01760	1.27e-249	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
DGNHLHCD_01761	6.63e-52	-	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
DGNHLHCD_01762	3.56e-145	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DGNHLHCD_01763	7.89e-270	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
DGNHLHCD_01764	4.37e-289	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
DGNHLHCD_01765	3.86e-121	-	-	-	S	-	-	-	RloB-like protein
DGNHLHCD_01766	3.55e-254	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
DGNHLHCD_01767	1e-13	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
DGNHLHCD_01768	3.32e-253	-	-	-	L	-	-	-	Transposase, Mutator family
DGNHLHCD_01771	3.91e-230	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
DGNHLHCD_01772	2.92e-131	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
DGNHLHCD_01773	1.04e-249	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
DGNHLHCD_01774	0.0	-	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
DGNHLHCD_01775	5.49e-290	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DGNHLHCD_01776	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
DGNHLHCD_01777	9.86e-202	-	-	-	S	-	-	-	Putative ABC-transporter type IV
DGNHLHCD_01778	4.22e-211	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
DGNHLHCD_01779	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
DGNHLHCD_01783	7.09e-278	steT	-	-	E	ko:K03294	-	ko00000	amino acid
DGNHLHCD_01784	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
DGNHLHCD_01785	7.42e-41	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
DGNHLHCD_01787	6.35e-07	-	-	-	-	-	-	-	-
DGNHLHCD_01789	7.75e-258	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
DGNHLHCD_01790	1.39e-157	-	-	-	-	-	-	-	-
DGNHLHCD_01791	1.99e-250	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DGNHLHCD_01792	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
DGNHLHCD_01793	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
DGNHLHCD_01794	1.12e-49	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
DGNHLHCD_01796	1.88e-52	-	-	-	-	-	-	-	-
DGNHLHCD_01797	5.11e-146	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
DGNHLHCD_01799	7.79e-65	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DGNHLHCD_01800	8.63e-56	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DGNHLHCD_01802	4.79e-307	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
DGNHLHCD_01803	6.52e-139	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DGNHLHCD_01805	1.77e-178	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
DGNHLHCD_01806	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
DGNHLHCD_01807	6.36e-160	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DGNHLHCD_01808	6.07e-100	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
DGNHLHCD_01809	1.38e-187	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
DGNHLHCD_01812	2.36e-158	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
DGNHLHCD_01813	0.0	-	-	-	E	-	-	-	Serine carboxypeptidase
DGNHLHCD_01814	1.72e-208	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
DGNHLHCD_01815	1.72e-218	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
DGNHLHCD_01816	2.26e-215	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
DGNHLHCD_01819	2.04e-263	-	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
DGNHLHCD_01820	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
DGNHLHCD_01821	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
DGNHLHCD_01822	4.14e-95	-	2.7.1.162	-	S	ko:K13059	-	ko00000,ko01000	Phosphotransferase enzyme family
DGNHLHCD_01823	2.25e-151	-	2.7.1.162	-	S	ko:K13059	-	ko00000,ko01000	Phosphotransferase enzyme family
DGNHLHCD_01824	1.28e-277	-	-	-	GK	-	-	-	ROK family
DGNHLHCD_01825	1.69e-228	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
DGNHLHCD_01826	1.73e-70	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
DGNHLHCD_01827	3.3e-75	-	-	-	S	-	-	-	competence protein
DGNHLHCD_01828	9.07e-151	-	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
DGNHLHCD_01829	1.27e-10	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
DGNHLHCD_01830	1.9e-39	-	-	-	-	-	-	-	-
DGNHLHCD_01832	4.77e-247	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
DGNHLHCD_01833	3.66e-95	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DGNHLHCD_01834	4.66e-232	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
DGNHLHCD_01835	8.63e-180	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
DGNHLHCD_01837	7.42e-162	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
DGNHLHCD_01838	7.3e-219	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DGNHLHCD_01839	1.6e-83	-	-	-	-	-	-	-	-
DGNHLHCD_01840	9.35e-171	-	-	-	-	-	-	-	-
DGNHLHCD_01841	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DGNHLHCD_01842	1.72e-110	-	-	-	K	-	-	-	Transcriptional regulator
DGNHLHCD_01844	1.76e-46	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
DGNHLHCD_01845	3.23e-269	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
DGNHLHCD_01846	5.97e-19	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
DGNHLHCD_01847	5.49e-237	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
DGNHLHCD_01848	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
DGNHLHCD_01850	2.98e-214	-	-	-	S	-	-	-	Glutamine amidotransferase domain
DGNHLHCD_01851	4.97e-177	-	-	-	T	ko:K06950	-	ko00000	HD domain
DGNHLHCD_01852	2.3e-269	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
DGNHLHCD_01853	0.0	-	-	-	V	-	-	-	ABC transporter permease
DGNHLHCD_01854	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
DGNHLHCD_01855	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
DGNHLHCD_01856	1.93e-211	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
DGNHLHCD_01857	1.98e-36	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
DGNHLHCD_01858	0.00015	-	-	-	-	-	-	-	-
DGNHLHCD_01859	0.0	-	-	-	-	-	-	-	-
DGNHLHCD_01860	2.25e-265	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
DGNHLHCD_01861	3.15e-75	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
DGNHLHCD_01862	1.97e-56	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
DGNHLHCD_01863	3.04e-129	-	-	-	-	-	-	-	-
DGNHLHCD_01864	5.71e-257	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
DGNHLHCD_01865	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)