ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
GEPDGMEL_00007 8.55e-06 - - - - - - - -
GEPDGMEL_00008 5e-59 ydeP - - K - - - Transcriptional regulator, HxlR family
GEPDGMEL_00009 3.85e-206 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
GEPDGMEL_00010 2e-132 - - - L - - - Transposase and inactivated derivatives, IS30 family
GEPDGMEL_00011 1.05e-215 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GEPDGMEL_00012 1.79e-294 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GEPDGMEL_00013 2.51e-233 - - - G ko:K02752,ko:K02753,ko:K02755,ko:K02756,ko:K02757 ko00010,ko02060,map00010,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GEPDGMEL_00014 1.63e-99 - - - L - - - DnaB-like helicase C terminal domain
GEPDGMEL_00017 1.8e-42 - - - - - - - -
GEPDGMEL_00018 4.25e-108 - - - L - - - Transposase and inactivated derivatives, IS30 family
GEPDGMEL_00019 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
GEPDGMEL_00021 2.86e-287 - - - S ko:K07133 - ko00000 cog cog1373
GEPDGMEL_00022 3.25e-223 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
GEPDGMEL_00023 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GEPDGMEL_00024 9.14e-205 - - - EG - - - EamA-like transporter family
GEPDGMEL_00025 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
GEPDGMEL_00026 1.63e-312 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
GEPDGMEL_00027 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
GEPDGMEL_00028 2.81e-149 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
GEPDGMEL_00029 4.71e-162 pgm3 - - G - - - phosphoglycerate mutase
GEPDGMEL_00030 5.29e-300 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GEPDGMEL_00031 1.34e-47 - - - S - - - Transglycosylase associated protein
GEPDGMEL_00032 6.08e-13 - - - S - - - CsbD-like
GEPDGMEL_00033 3.66e-229 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GEPDGMEL_00034 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
GEPDGMEL_00035 2.14e-123 - - - K - - - Transcriptional regulator (TetR family)
GEPDGMEL_00036 2.39e-50 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
GEPDGMEL_00037 1.1e-191 - - - - - - - -
GEPDGMEL_00038 6.51e-31 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
GEPDGMEL_00039 1.27e-108 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
GEPDGMEL_00040 2.37e-133 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
GEPDGMEL_00041 1.03e-96 - - - F - - - Nudix hydrolase
GEPDGMEL_00042 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
GEPDGMEL_00043 1.3e-300 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
GEPDGMEL_00044 4.14e-295 - - - - - - - -
GEPDGMEL_00045 2.08e-267 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GEPDGMEL_00046 2.56e-182 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GEPDGMEL_00047 2.49e-187 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GEPDGMEL_00048 5.08e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GEPDGMEL_00049 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GEPDGMEL_00050 1.5e-226 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
GEPDGMEL_00051 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
GEPDGMEL_00052 6.98e-137 - - - L - - - Helix-turn-helix domain
GEPDGMEL_00053 1.72e-213 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
GEPDGMEL_00054 3.23e-75 - - - S - - - Small secreted protein
GEPDGMEL_00055 2.95e-75 ytpP - - CO - - - Thioredoxin
GEPDGMEL_00056 1.63e-152 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GEPDGMEL_00057 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
GEPDGMEL_00058 3.74e-153 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
GEPDGMEL_00059 2.05e-155 - - - S - - - Protein of unknown function (DUF1275)
GEPDGMEL_00060 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GEPDGMEL_00061 9.85e-198 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GEPDGMEL_00062 3.99e-127 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GEPDGMEL_00063 2.82e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GEPDGMEL_00064 5.97e-302 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
GEPDGMEL_00065 2.11e-222 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
GEPDGMEL_00066 1.07e-110 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GEPDGMEL_00067 1.82e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
GEPDGMEL_00068 5.46e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GEPDGMEL_00069 7.78e-125 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
GEPDGMEL_00070 1.56e-278 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
GEPDGMEL_00071 5.4e-63 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
GEPDGMEL_00072 4.9e-158 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GEPDGMEL_00073 1.46e-145 yqeK - - H - - - Hydrolase, HD family
GEPDGMEL_00074 2.69e-79 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GEPDGMEL_00075 1.19e-174 yqeM - - Q - - - Methyltransferase
GEPDGMEL_00076 3.38e-274 ylbM - - S - - - Belongs to the UPF0348 family
GEPDGMEL_00077 1.01e-129 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
GEPDGMEL_00078 7.21e-39 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
GEPDGMEL_00079 9.72e-156 csrR - - K - - - response regulator
GEPDGMEL_00080 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GEPDGMEL_00081 0.0 potE - - E - - - Amino Acid
GEPDGMEL_00082 1.74e-291 - - - V - - - MatE
GEPDGMEL_00083 3.32e-93 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
GEPDGMEL_00084 3.19e-214 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GEPDGMEL_00085 2.45e-58 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
GEPDGMEL_00086 2.71e-186 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GEPDGMEL_00087 3.75e-119 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
GEPDGMEL_00088 5.79e-78 yodB - - K - - - Transcriptional regulator, HxlR family
GEPDGMEL_00089 1.22e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GEPDGMEL_00090 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GEPDGMEL_00091 2.41e-148 - - - M - - - PFAM NLP P60 protein
GEPDGMEL_00092 2.06e-152 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
GEPDGMEL_00093 6.08e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GEPDGMEL_00094 2.77e-82 yneR - - S - - - Belongs to the HesB IscA family
GEPDGMEL_00095 0.0 - - - S - - - membrane
GEPDGMEL_00096 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GEPDGMEL_00097 1.53e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
GEPDGMEL_00098 6.32e-128 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GEPDGMEL_00099 1.13e-145 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
GEPDGMEL_00100 7.07e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
GEPDGMEL_00101 2.51e-235 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
GEPDGMEL_00102 7.66e-88 yqhL - - P - - - Rhodanese-like protein
GEPDGMEL_00103 1.18e-30 - - - S - - - Protein of unknown function (DUF3042)
GEPDGMEL_00104 4.12e-226 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GEPDGMEL_00105 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
GEPDGMEL_00106 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GEPDGMEL_00107 6.2e-285 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GEPDGMEL_00108 1.28e-18 - - - - - - - -
GEPDGMEL_00109 3.65e-160 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GEPDGMEL_00110 5.46e-108 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
GEPDGMEL_00111 8.81e-317 yagE - - E - - - amino acid
GEPDGMEL_00112 4.5e-150 - - - S - - - HAD hydrolase, family IA, variant
GEPDGMEL_00113 4.85e-233 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
GEPDGMEL_00114 6.65e-234 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
GEPDGMEL_00115 1.05e-175 - - - IQ - - - KR domain
GEPDGMEL_00116 1.03e-171 - - - S ko:K07090 - ko00000 membrane transporter protein
GEPDGMEL_00117 5.18e-128 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
GEPDGMEL_00118 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GEPDGMEL_00119 8.69e-149 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
GEPDGMEL_00120 6.5e-71 - - - - - - - -
GEPDGMEL_00121 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
GEPDGMEL_00122 1.28e-68 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
GEPDGMEL_00123 3.6e-241 ybcH - - D ko:K06889 - ko00000 Alpha beta
GEPDGMEL_00124 1.3e-95 - - - K - - - Transcriptional regulator
GEPDGMEL_00125 1.65e-205 - - - - - - - -
GEPDGMEL_00126 3.67e-43 - - - C - - - Zinc-binding dehydrogenase
GEPDGMEL_00127 1.56e-81 - - - C - - - Zinc-binding dehydrogenase
GEPDGMEL_00128 3.39e-49 - - - C - - - Zinc-binding dehydrogenase
GEPDGMEL_00129 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
GEPDGMEL_00130 1.6e-269 - - - EGP - - - Major Facilitator
GEPDGMEL_00131 1.67e-177 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
GEPDGMEL_00132 2.01e-152 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
GEPDGMEL_00133 3.18e-11 - - - - - - - -
GEPDGMEL_00134 1.78e-83 - - - - - - - -
GEPDGMEL_00135 8.24e-248 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
GEPDGMEL_00136 7.46e-106 uspA3 - - T - - - universal stress protein
GEPDGMEL_00137 0.0 fusA1 - - J - - - elongation factor G
GEPDGMEL_00138 4.39e-213 - - - GK - - - ROK family
GEPDGMEL_00139 3.97e-310 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
GEPDGMEL_00140 4.31e-178 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
GEPDGMEL_00141 3.29e-299 - - - E - - - amino acid
GEPDGMEL_00142 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
GEPDGMEL_00143 1.05e-171 gntR - - K - - - UbiC transcription regulator-associated domain protein
GEPDGMEL_00144 2.85e-114 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GEPDGMEL_00145 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GEPDGMEL_00146 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
GEPDGMEL_00147 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
GEPDGMEL_00148 3.19e-239 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GEPDGMEL_00149 1.19e-173 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
GEPDGMEL_00150 1.52e-210 - - - - - - - -
GEPDGMEL_00151 4.91e-205 - - - G - - - Xylose isomerase domain protein TIM barrel
GEPDGMEL_00152 1.68e-239 XK27_12525 - - S - - - AI-2E family transporter
GEPDGMEL_00153 1.56e-172 XK27_07210 - - S - - - B3 4 domain
GEPDGMEL_00154 1.93e-101 yybA - - K - - - Transcriptional regulator
GEPDGMEL_00155 5.25e-118 - - - K - - - Domain of unknown function (DUF1836)
GEPDGMEL_00156 1.63e-116 - - - GM - - - epimerase
GEPDGMEL_00157 4.86e-199 - - - V - - - (ABC) transporter
GEPDGMEL_00158 5e-309 yhdP - - S - - - Transporter associated domain
GEPDGMEL_00159 4e-110 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
GEPDGMEL_00160 4.3e-96 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
GEPDGMEL_00161 5.09e-244 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
GEPDGMEL_00162 1.17e-22 isp - - L - - - Transposase
GEPDGMEL_00163 4.35e-80 - - - L - - - Transposase
GEPDGMEL_00164 3.67e-126 isp - - L - - - Transposase
GEPDGMEL_00165 1.17e-305 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
GEPDGMEL_00166 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
GEPDGMEL_00167 9.29e-143 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GEPDGMEL_00168 3.97e-198 - - - O - - - Uncharacterized protein family (UPF0051)
GEPDGMEL_00169 1.73e-151 - - - M - - - LysM domain protein
GEPDGMEL_00170 0.0 - - - EP - - - Psort location Cytoplasmic, score
GEPDGMEL_00171 1.1e-131 - - - M - - - LysM domain protein
GEPDGMEL_00172 2.95e-192 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
GEPDGMEL_00173 6.91e-299 - 1.3.1.1 - E ko:K17722 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
GEPDGMEL_00174 3.25e-309 - 1.3.1.1 - C ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
GEPDGMEL_00175 8.69e-195 yeaE - - S - - - Aldo keto
GEPDGMEL_00176 4.63e-101 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
GEPDGMEL_00177 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
GEPDGMEL_00178 4.58e-103 - - - S - - - Psort location Cytoplasmic, score
GEPDGMEL_00179 4.13e-110 - - - S - - - Short repeat of unknown function (DUF308)
GEPDGMEL_00180 7.03e-33 - - - - - - - -
GEPDGMEL_00181 1.37e-133 - - - V - - - VanZ like family
GEPDGMEL_00182 1.58e-299 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
GEPDGMEL_00183 3.59e-111 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
GEPDGMEL_00184 0.0 - - - EGP - - - Major Facilitator
GEPDGMEL_00185 3.41e-125 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
GEPDGMEL_00186 6.66e-281 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GEPDGMEL_00187 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
GEPDGMEL_00188 2.07e-55 - - - - - - - -
GEPDGMEL_00189 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
GEPDGMEL_00190 2.67e-191 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GEPDGMEL_00191 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
GEPDGMEL_00192 4.4e-112 - - - T - - - Belongs to the universal stress protein A family
GEPDGMEL_00193 3.04e-222 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GEPDGMEL_00194 3.06e-150 dgk2 - - F - - - deoxynucleoside kinase
GEPDGMEL_00195 1.53e-146 - - - - - - - -
GEPDGMEL_00196 2.41e-236 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
GEPDGMEL_00197 1.63e-207 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GEPDGMEL_00198 1.52e-43 - - - - - - - -
GEPDGMEL_00199 1.43e-151 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
GEPDGMEL_00200 9.17e-59 - - - - - - - -
GEPDGMEL_00202 2.57e-90 - - - - - - - -
GEPDGMEL_00203 1.43e-73 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GEPDGMEL_00204 6.46e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
GEPDGMEL_00205 1.17e-136 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
GEPDGMEL_00206 1.11e-282 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
GEPDGMEL_00207 1.72e-135 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
GEPDGMEL_00208 4.98e-272 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
GEPDGMEL_00209 1.88e-60 - - - - - - - -
GEPDGMEL_00210 4.26e-54 - - - - - - - -
GEPDGMEL_00212 6.43e-212 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GEPDGMEL_00213 1.69e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
GEPDGMEL_00214 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
GEPDGMEL_00215 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
GEPDGMEL_00216 7.66e-192 - - - O - - - Band 7 protein
GEPDGMEL_00217 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 LytS YhcK-type transmembrane receptor domain protein
GEPDGMEL_00218 8.34e-99 lytT - - K ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator receiver
GEPDGMEL_00219 3.69e-87 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
GEPDGMEL_00220 1.78e-160 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
GEPDGMEL_00221 8.01e-228 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GEPDGMEL_00222 7.64e-219 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
GEPDGMEL_00223 5.04e-234 galR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
GEPDGMEL_00224 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
GEPDGMEL_00225 6.82e-119 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
GEPDGMEL_00226 8.91e-248 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GEPDGMEL_00227 1.95e-272 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
GEPDGMEL_00228 5.83e-225 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
GEPDGMEL_00229 2.98e-219 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
GEPDGMEL_00230 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
GEPDGMEL_00231 6.66e-115 ypmB - - S - - - Protein conserved in bacteria
GEPDGMEL_00232 9.68e-159 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
GEPDGMEL_00233 2.32e-206 - - - EG - - - EamA-like transporter family
GEPDGMEL_00234 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
GEPDGMEL_00235 4.06e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GEPDGMEL_00236 3.63e-130 ypsA - - S - - - Belongs to the UPF0398 family
GEPDGMEL_00237 6.82e-74 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GEPDGMEL_00238 4.13e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
GEPDGMEL_00239 4.18e-283 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
GEPDGMEL_00240 1.09e-91 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
GEPDGMEL_00241 2.58e-85 esbA - - S - - - Family of unknown function (DUF5322)
GEPDGMEL_00242 8.16e-93 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GEPDGMEL_00243 1.96e-222 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GEPDGMEL_00244 2.62e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
GEPDGMEL_00245 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
GEPDGMEL_00246 0.0 FbpA - - K - - - Fibronectin-binding protein
GEPDGMEL_00247 2.95e-207 - - - S - - - EDD domain protein, DegV family
GEPDGMEL_00248 7.18e-126 - - - - - - - -
GEPDGMEL_00249 1.24e-153 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
GEPDGMEL_00250 8.83e-173 gspA - - M - - - family 8
GEPDGMEL_00251 2.43e-205 - - - S - - - Alpha beta hydrolase
GEPDGMEL_00252 4.52e-123 - - - K - - - Acetyltransferase (GNAT) domain
GEPDGMEL_00253 2.37e-158 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
GEPDGMEL_00254 1.24e-68 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
GEPDGMEL_00255 6.59e-23 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
GEPDGMEL_00256 1.45e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
GEPDGMEL_00257 7.9e-214 yvgN - - C - - - Aldo keto reductase
GEPDGMEL_00258 3.37e-57 - - - K - - - Transcriptional regulator
GEPDGMEL_00259 1.69e-103 - - - S - - - Cupin domain
GEPDGMEL_00260 2.72e-97 - - - S - - - UPF0756 membrane protein
GEPDGMEL_00261 4.8e-308 - - - U - - - Belongs to the major facilitator superfamily
GEPDGMEL_00262 2.39e-98 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
GEPDGMEL_00263 3.3e-315 yhdP - - S - - - Transporter associated domain
GEPDGMEL_00264 2e-241 - - - M - - - Rib/alpha-like repeat
GEPDGMEL_00265 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GEPDGMEL_00266 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GEPDGMEL_00267 5.67e-178 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GEPDGMEL_00268 2.15e-286 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
GEPDGMEL_00269 3.98e-277 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
GEPDGMEL_00270 2.03e-219 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
GEPDGMEL_00271 8.47e-208 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
GEPDGMEL_00272 3.95e-166 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
GEPDGMEL_00273 7.52e-200 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
GEPDGMEL_00274 2.79e-178 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
GEPDGMEL_00275 4.83e-198 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
GEPDGMEL_00276 5.8e-43 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
GEPDGMEL_00277 6.1e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GEPDGMEL_00278 1.04e-173 - - - S - - - Protein of unknown function (DUF1129)
GEPDGMEL_00279 1.62e-152 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GEPDGMEL_00280 6.87e-300 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
GEPDGMEL_00281 5.76e-303 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
GEPDGMEL_00282 7.71e-166 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
GEPDGMEL_00283 2.18e-218 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
GEPDGMEL_00284 2.84e-263 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GEPDGMEL_00285 9.76e-161 vanR - - K - - - response regulator
GEPDGMEL_00286 6.19e-263 hpk31 - - T - - - Histidine kinase
GEPDGMEL_00287 3.97e-185 - - - E - - - AzlC protein
GEPDGMEL_00288 9.94e-71 - - - S - - - branched-chain amino acid
GEPDGMEL_00289 4.84e-180 - - - K - - - LysR substrate binding domain
GEPDGMEL_00290 1.81e-221 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
GEPDGMEL_00291 1.75e-312 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GEPDGMEL_00292 2.66e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GEPDGMEL_00293 1.96e-167 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GEPDGMEL_00294 9.09e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GEPDGMEL_00295 2.61e-148 - - - S - - - Haloacid dehalogenase-like hydrolase
GEPDGMEL_00296 2.33e-291 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
GEPDGMEL_00297 1.84e-223 ydbI - - K - - - AI-2E family transporter
GEPDGMEL_00298 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
GEPDGMEL_00299 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
GEPDGMEL_00300 1.95e-160 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
GEPDGMEL_00301 3.79e-234 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
GEPDGMEL_00302 3.61e-219 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
GEPDGMEL_00303 1.16e-125 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GEPDGMEL_00304 2.44e-206 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GEPDGMEL_00305 7.88e-50 veg - - S - - - Biofilm formation stimulator VEG
GEPDGMEL_00306 1.85e-208 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GEPDGMEL_00307 3.49e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GEPDGMEL_00308 4.18e-197 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
GEPDGMEL_00309 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GEPDGMEL_00310 9.18e-206 yunF - - F - - - Protein of unknown function DUF72
GEPDGMEL_00312 4.16e-168 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
GEPDGMEL_00313 4.27e-225 - - - - - - - -
GEPDGMEL_00314 1.17e-289 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
GEPDGMEL_00315 2.53e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
GEPDGMEL_00316 4.55e-242 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
GEPDGMEL_00317 5.96e-241 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
GEPDGMEL_00318 1.17e-105 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
GEPDGMEL_00319 0.0 - - - L - - - DNA helicase
GEPDGMEL_00320 1.67e-255 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GEPDGMEL_00321 2.47e-250 eriC - - P ko:K03281 - ko00000 chloride
GEPDGMEL_00322 3.31e-53 - - - L - - - Transposase, IS116 IS110 IS902 family
GEPDGMEL_00324 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GEPDGMEL_00325 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
GEPDGMEL_00326 1.91e-150 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GEPDGMEL_00327 5.98e-55 - 1.3.5.4 - S ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN binding
GEPDGMEL_00328 5.93e-281 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
GEPDGMEL_00329 5.14e-217 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
GEPDGMEL_00330 3.28e-195 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GEPDGMEL_00331 2.44e-244 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GEPDGMEL_00332 1.06e-139 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GEPDGMEL_00333 1.44e-277 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
GEPDGMEL_00334 6.19e-33 eriC - - P ko:K03281 - ko00000 chloride
GEPDGMEL_00335 3.24e-124 eriC - - P ko:K03281 - ko00000 chloride
GEPDGMEL_00336 3.14e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
GEPDGMEL_00337 1.38e-138 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
GEPDGMEL_00338 7.44e-183 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GEPDGMEL_00339 5.77e-140 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GEPDGMEL_00340 3.07e-208 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
GEPDGMEL_00341 1.4e-99 ywnA - - K - - - Transcriptional regulator
GEPDGMEL_00342 6.36e-12 - - - GM - - - NAD(P)H-binding
GEPDGMEL_00343 6.61e-277 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
GEPDGMEL_00344 0.0 cadA - - P - - - P-type ATPase
GEPDGMEL_00345 1.31e-161 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
GEPDGMEL_00346 4.29e-162 - - - - - - - -
GEPDGMEL_00347 2.84e-73 - - - S - - - Sugar efflux transporter for intercellular exchange
GEPDGMEL_00348 0.0 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
GEPDGMEL_00349 5.24e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GEPDGMEL_00350 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
GEPDGMEL_00351 2e-283 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GEPDGMEL_00352 4.23e-76 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GEPDGMEL_00353 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GEPDGMEL_00354 1.21e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
GEPDGMEL_00355 4.38e-52 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
GEPDGMEL_00356 2.96e-116 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GEPDGMEL_00357 7.76e-183 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
GEPDGMEL_00358 0.0 - - - E ko:K03294 - ko00000 amino acid
GEPDGMEL_00359 3.75e-77 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GEPDGMEL_00360 3.94e-45 - - - - - - - -
GEPDGMEL_00361 2.58e-71 - - - S - - - Mazg nucleotide pyrophosphohydrolase
GEPDGMEL_00362 2.17e-205 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
GEPDGMEL_00363 3.81e-110 - - - - - - - -
GEPDGMEL_00364 1.16e-239 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
GEPDGMEL_00365 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
GEPDGMEL_00366 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
GEPDGMEL_00367 3.5e-223 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GEPDGMEL_00368 1.1e-201 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
GEPDGMEL_00369 7.79e-185 XK27_00940 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Putative cyclase
GEPDGMEL_00370 1.15e-282 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
GEPDGMEL_00371 2.14e-166 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GEPDGMEL_00372 1.81e-291 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
GEPDGMEL_00373 2.76e-212 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
GEPDGMEL_00374 2.48e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GEPDGMEL_00376 4.32e-155 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
GEPDGMEL_00377 2.65e-190 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GEPDGMEL_00378 6.57e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
GEPDGMEL_00379 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
GEPDGMEL_00380 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
GEPDGMEL_00381 4.16e-53 - - - S - - - glycosyl transferase family 2
GEPDGMEL_00382 1.27e-61 - - - S - - - glycosyl transferase family 2
GEPDGMEL_00383 4.22e-49 - - - M - - - family 8
GEPDGMEL_00384 1.28e-211 - - - C - - - Aldo keto reductase
GEPDGMEL_00385 6.23e-62 - - - S - - - Cupin 2, conserved barrel domain protein
GEPDGMEL_00386 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
GEPDGMEL_00387 6.51e-114 - - - S - - - ECF-type riboflavin transporter, S component
GEPDGMEL_00388 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
GEPDGMEL_00389 2.5e-231 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GEPDGMEL_00390 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GEPDGMEL_00391 5.96e-120 - - - - - - - -
GEPDGMEL_00392 1.82e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GEPDGMEL_00394 8.02e-174 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
GEPDGMEL_00395 1.49e-133 - - - E - - - amino acid
GEPDGMEL_00396 9.1e-159 - - - E - - - amino acid
GEPDGMEL_00397 2.8e-143 - - - K - - - Transcriptional regulator, TetR family
GEPDGMEL_00398 1.25e-93 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
GEPDGMEL_00399 1.05e-33 - - - S - - - ABC-type transport system involved in multi-copper enzyme maturation permease component
GEPDGMEL_00400 3.91e-91 - - - - - - - -
GEPDGMEL_00401 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
GEPDGMEL_00402 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
GEPDGMEL_00403 0.0 sdrF - - M ko:K14194 ko05150,map05150 ko00000,ko00001 protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
GEPDGMEL_00404 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
GEPDGMEL_00405 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
GEPDGMEL_00406 1.14e-88 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
GEPDGMEL_00407 1.04e-191 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
GEPDGMEL_00408 6.91e-235 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
GEPDGMEL_00409 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GEPDGMEL_00410 1.72e-128 - 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
GEPDGMEL_00411 7.05e-273 - 1.5.1.36 - S ko:K19784,ko:K22393,ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
GEPDGMEL_00412 2.58e-225 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GEPDGMEL_00413 4.62e-81 - - - S - - - Domain of unknown function (DUF4828)
GEPDGMEL_00414 2.54e-243 mocA - - S - - - Oxidoreductase
GEPDGMEL_00415 1.22e-292 yfmL - - L - - - DEAD DEAH box helicase
GEPDGMEL_00417 4.71e-263 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GEPDGMEL_00418 1.42e-72 - - - - - - - -
GEPDGMEL_00419 8.59e-98 gtcA - - S - - - Teichoic acid glycosylation protein
GEPDGMEL_00420 4.7e-103 ykuP - - C ko:K03839 - ko00000 Flavodoxin
GEPDGMEL_00421 1e-215 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
GEPDGMEL_00422 2.8e-280 arcT - - E - - - Aminotransferase
GEPDGMEL_00423 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
GEPDGMEL_00424 0.0 potE - - E - - - Amino Acid
GEPDGMEL_00425 1.5e-198 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
GEPDGMEL_00426 4.23e-45 - - - S - - - Protein of unknown function (DUF2922)
GEPDGMEL_00427 2.53e-42 - - - - - - - -
GEPDGMEL_00428 1.07e-170 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
GEPDGMEL_00429 3.17e-188 cps1D - - M - - - Domain of unknown function (DUF4422)
GEPDGMEL_00430 8.95e-222 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
GEPDGMEL_00431 3.3e-152 - - - M - - - Bacterial sugar transferase
GEPDGMEL_00432 0.0 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
GEPDGMEL_00433 0.0 - - - G - - - Peptidase_C39 like family
GEPDGMEL_00434 1.65e-42 - - - - - - - -
GEPDGMEL_00435 5.85e-277 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
GEPDGMEL_00436 1.62e-263 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
GEPDGMEL_00437 8.59e-95 - - - M - - - transferase activity, transferring glycosyl groups
GEPDGMEL_00438 1.23e-107 - - - - - - - -
GEPDGMEL_00439 9.63e-38 - - - M - - - biosynthesis protein
GEPDGMEL_00440 7.78e-96 - - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 2
GEPDGMEL_00441 7.27e-83 - - - S - - - Glycosyltransferase like family
GEPDGMEL_00442 4.99e-98 - - - S ko:K07011 - ko00000 Glycosyltransferase, group 2 family protein
GEPDGMEL_00443 6.66e-95 - - - - - - - -
GEPDGMEL_00444 2.21e-181 - - - M - - - Glycosyl transferase family 2
GEPDGMEL_00445 0.0 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GEPDGMEL_00447 1.3e-204 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GEPDGMEL_00448 1.1e-126 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
GEPDGMEL_00449 1.39e-92 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GEPDGMEL_00450 8.31e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GEPDGMEL_00451 5.57e-290 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
GEPDGMEL_00453 1.2e-298 - - - M - - - Glycosyl transferase family group 2
GEPDGMEL_00454 1.21e-265 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GEPDGMEL_00455 3.6e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GEPDGMEL_00456 1.42e-71 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GEPDGMEL_00457 1.68e-64 - - - - - - - -
GEPDGMEL_00459 2.94e-65 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GEPDGMEL_00460 9.71e-76 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
GEPDGMEL_00461 8.01e-129 - - - S - - - Protein of unknown function (DUF1700)
GEPDGMEL_00462 1.49e-175 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
GEPDGMEL_00463 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
GEPDGMEL_00464 3.81e-254 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GEPDGMEL_00465 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GEPDGMEL_00466 9.33e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
GEPDGMEL_00467 1.25e-118 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GEPDGMEL_00468 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GEPDGMEL_00469 6.86e-61 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GEPDGMEL_00470 4.92e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GEPDGMEL_00471 4.67e-52 - - - S - - - Protein of unknown function (DUF2508)
GEPDGMEL_00472 6.4e-149 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GEPDGMEL_00473 2.83e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
GEPDGMEL_00474 3.7e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
GEPDGMEL_00475 3.71e-76 yabA - - L - - - Involved in initiation control of chromosome replication
GEPDGMEL_00476 9.08e-200 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GEPDGMEL_00477 1.28e-177 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
GEPDGMEL_00478 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
GEPDGMEL_00479 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GEPDGMEL_00480 6.8e-224 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
GEPDGMEL_00481 1.48e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
GEPDGMEL_00482 3.64e-162 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
GEPDGMEL_00483 2.04e-133 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
GEPDGMEL_00484 1.37e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GEPDGMEL_00485 3.77e-172 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GEPDGMEL_00486 1e-287 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GEPDGMEL_00487 1.27e-177 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GEPDGMEL_00488 1.89e-183 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
GEPDGMEL_00489 1.47e-287 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GEPDGMEL_00490 2.41e-232 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GEPDGMEL_00491 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
GEPDGMEL_00492 4.67e-147 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GEPDGMEL_00493 1.83e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GEPDGMEL_00494 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GEPDGMEL_00495 9e-44 - - - S ko:K19055 - ko00000,ko01000,ko03016 YbaK proline--tRNA ligase associated domain protein
GEPDGMEL_00496 7.42e-44 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
GEPDGMEL_00497 0.0 - - - E - - - amino acid
GEPDGMEL_00498 0.0 ydaO - - E - - - amino acid
GEPDGMEL_00499 1.78e-51 - - - - - - - -
GEPDGMEL_00500 2.95e-87 - - - K - - - Transcriptional regulator
GEPDGMEL_00501 4.32e-145 - - - EGP - - - Major Facilitator
GEPDGMEL_00502 7.42e-101 - - - EGP - - - Major Facilitator
GEPDGMEL_00503 1.29e-142 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
GEPDGMEL_00504 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
GEPDGMEL_00505 1.98e-163 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
GEPDGMEL_00506 2.89e-123 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GEPDGMEL_00507 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GEPDGMEL_00508 1.11e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GEPDGMEL_00509 2.47e-65 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
GEPDGMEL_00510 1.88e-68 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
GEPDGMEL_00511 2.29e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GEPDGMEL_00512 3.18e-198 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GEPDGMEL_00513 3.83e-233 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
GEPDGMEL_00514 1.08e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
GEPDGMEL_00515 2.5e-175 lutC - - S ko:K00782 - ko00000 LUD domain
GEPDGMEL_00516 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
GEPDGMEL_00517 1.07e-209 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
GEPDGMEL_00518 8.29e-223 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GEPDGMEL_00519 3.23e-269 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
GEPDGMEL_00520 2.96e-208 - - - ET ko:K02030 - ko00000,ko00002,ko02000 PFAM extracellular solute-binding protein, family 3
GEPDGMEL_00521 1.36e-112 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
GEPDGMEL_00522 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
GEPDGMEL_00523 3.57e-150 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
GEPDGMEL_00524 1.03e-19 - - - - - - - -
GEPDGMEL_00525 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GEPDGMEL_00526 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GEPDGMEL_00527 0.0 steT - - E ko:K03294 - ko00000 amino acid
GEPDGMEL_00528 3.83e-206 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
GEPDGMEL_00529 1.41e-239 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
GEPDGMEL_00530 1.37e-218 whiA - - K ko:K09762 - ko00000 May be required for sporulation
GEPDGMEL_00532 1.83e-21 - - - - - - - -
GEPDGMEL_00533 1.01e-308 glpT - - G ko:K02445 - ko00000,ko02000 Major Facilitator Superfamily
GEPDGMEL_00534 4.72e-134 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GEPDGMEL_00536 1.31e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GEPDGMEL_00537 7.62e-290 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
GEPDGMEL_00538 1.76e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GEPDGMEL_00539 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GEPDGMEL_00540 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
GEPDGMEL_00541 0.0 eriC - - P ko:K03281 - ko00000 chloride
GEPDGMEL_00542 5.82e-47 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
GEPDGMEL_00543 1.63e-187 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
GEPDGMEL_00544 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GEPDGMEL_00545 7.73e-109 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GEPDGMEL_00546 9.61e-137 - - - - - - - -
GEPDGMEL_00547 6.17e-173 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GEPDGMEL_00548 1.97e-228 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
GEPDGMEL_00549 1.71e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
GEPDGMEL_00550 6.2e-114 - - - K - - - Acetyltransferase (GNAT) domain
GEPDGMEL_00551 2.92e-98 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
GEPDGMEL_00552 3.7e-133 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
GEPDGMEL_00553 3.36e-216 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
GEPDGMEL_00554 3.08e-212 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GEPDGMEL_00555 1.01e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
GEPDGMEL_00556 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
GEPDGMEL_00557 4.46e-193 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GEPDGMEL_00558 3.51e-161 ybbR - - S - - - YbbR-like protein
GEPDGMEL_00559 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GEPDGMEL_00560 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GEPDGMEL_00561 1.04e-69 - - - - - - - -
GEPDGMEL_00562 0.0 oatA - - I - - - Acyltransferase
GEPDGMEL_00563 1.23e-103 - - - K - - - Transcriptional regulator
GEPDGMEL_00564 5.24e-189 - - - S - - - Cof-like hydrolase
GEPDGMEL_00565 1.31e-108 lytE - - M - - - Lysin motif
GEPDGMEL_00572 1.48e-20 - - - K - - - Cro/C1-type HTH DNA-binding domain
GEPDGMEL_00573 8.63e-64 - - - - - - - -
GEPDGMEL_00576 1.2e-36 - - - - - - - -
GEPDGMEL_00577 7.15e-38 - - - D - - - Antitoxin component of a toxin-antitoxin (TA) module
GEPDGMEL_00578 2.88e-35 - - - S - - - YoeB-like toxin of bacterial type II toxin-antitoxin system
GEPDGMEL_00585 3.12e-55 - - - L - - - Belongs to the 'phage' integrase family
GEPDGMEL_00586 2.31e-173 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
GEPDGMEL_00587 0.0 yclK - - T - - - Histidine kinase
GEPDGMEL_00588 7.78e-200 - - - U ko:K05340 - ko00000,ko02000 sugar transport
GEPDGMEL_00589 1.53e-147 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
GEPDGMEL_00590 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
GEPDGMEL_00591 2.49e-39 - - - - - - - -
GEPDGMEL_00592 5.23e-277 xylR - - GK - - - ROK family
GEPDGMEL_00594 0.0 xylT - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GEPDGMEL_00595 8.96e-223 rhaS2 - - K - - - Transcriptional regulator, AraC family
GEPDGMEL_00596 0.0 - - - G ko:K03292 - ko00000 MFS/sugar transport protein
GEPDGMEL_00597 0.0 - - - G - - - Right handed beta helix region
GEPDGMEL_00598 3.24e-58 pgdA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 polysaccharide deacetylase
GEPDGMEL_00599 8.8e-17 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 polysaccharide deacetylase
GEPDGMEL_00600 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
GEPDGMEL_00601 0.0 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
GEPDGMEL_00602 4.34e-198 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
GEPDGMEL_00603 3.21e-244 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GEPDGMEL_00604 2.28e-220 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
GEPDGMEL_00605 3.97e-200 - - - EG - - - EamA-like transporter family
GEPDGMEL_00606 9.98e-134 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
GEPDGMEL_00607 1.6e-82 - - - S - - - Cupredoxin-like domain
GEPDGMEL_00608 2.2e-65 - - - S - - - Cupredoxin-like domain
GEPDGMEL_00609 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
GEPDGMEL_00610 2.69e-114 - - - - - - - -
GEPDGMEL_00612 1.28e-75 - - - - - - - -
GEPDGMEL_00613 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
GEPDGMEL_00615 2.27e-138 - - - - - - - -
GEPDGMEL_00616 0.0 - - - M - - - domain protein
GEPDGMEL_00617 3.83e-74 - - - - - - - -
GEPDGMEL_00618 4.91e-241 ampC - - V - - - Beta-lactamase
GEPDGMEL_00619 5.94e-303 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
GEPDGMEL_00620 6.17e-104 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
GEPDGMEL_00621 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
GEPDGMEL_00622 4.84e-298 potE - - U ko:K03756,ko:K03758 - ko00000,ko02000 Amino acid permease
GEPDGMEL_00624 1.63e-171 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
GEPDGMEL_00625 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
GEPDGMEL_00626 6.8e-140 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
GEPDGMEL_00627 1.73e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GEPDGMEL_00628 1.31e-208 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GEPDGMEL_00629 6.29e-250 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GEPDGMEL_00630 2.58e-293 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GEPDGMEL_00631 6.68e-150 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GEPDGMEL_00632 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GEPDGMEL_00633 4.52e-244 yibE - - S - - - overlaps another CDS with the same product name
GEPDGMEL_00634 1.35e-165 yibF - - S - - - overlaps another CDS with the same product name
GEPDGMEL_00635 1.62e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
GEPDGMEL_00636 3.8e-161 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
GEPDGMEL_00637 1.26e-29 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GEPDGMEL_00638 1.07e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GEPDGMEL_00639 1.14e-119 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GEPDGMEL_00640 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GEPDGMEL_00641 1.3e-212 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GEPDGMEL_00642 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GEPDGMEL_00643 8.95e-90 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
GEPDGMEL_00644 5.05e-45 ywzB - - S - - - Protein of unknown function (DUF1146)
GEPDGMEL_00645 1.81e-309 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GEPDGMEL_00646 2.57e-227 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
GEPDGMEL_00647 4.61e-44 - - - S - - - Protein of unknown function (DUF2969)
GEPDGMEL_00648 9.49e-282 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
GEPDGMEL_00649 1.21e-63 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
GEPDGMEL_00650 6.32e-275 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
GEPDGMEL_00651 1.49e-190 - - - K - - - Helix-turn-helix XRE-family like proteins
GEPDGMEL_00652 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GEPDGMEL_00653 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
GEPDGMEL_00654 1.91e-178 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
GEPDGMEL_00655 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
GEPDGMEL_00656 1.65e-121 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
GEPDGMEL_00657 4.01e-199 yvgN - - S - - - Aldo keto reductase
GEPDGMEL_00658 5.46e-258 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
GEPDGMEL_00659 1.95e-109 uspA - - T - - - universal stress protein
GEPDGMEL_00660 3.61e-61 - - - - - - - -
GEPDGMEL_00661 7.66e-309 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
GEPDGMEL_00662 2.47e-112 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
GEPDGMEL_00663 1.97e-28 - - - - - - - -
GEPDGMEL_00664 1.16e-97 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
GEPDGMEL_00665 2.41e-179 - - - S - - - Membrane
GEPDGMEL_00666 1.23e-173 - - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
GEPDGMEL_00667 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
GEPDGMEL_00668 0.0 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GEPDGMEL_00669 2.97e-124 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
GEPDGMEL_00670 1.78e-230 gadC - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
GEPDGMEL_00671 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
GEPDGMEL_00672 2.25e-201 - - - L ko:K07497 - ko00000 hmm pf00665
GEPDGMEL_00673 4.62e-163 - - - L - - - Helix-turn-helix domain
GEPDGMEL_00674 3.24e-258 pbuG - - S ko:K06901 - ko00000,ko02000 permease
GEPDGMEL_00675 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
GEPDGMEL_00676 3.95e-199 gadC - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
GEPDGMEL_00677 1.78e-115 gadC - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
GEPDGMEL_00680 8.53e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GEPDGMEL_00681 1.78e-57 - - - K - - - HxlR-like helix-turn-helix
GEPDGMEL_00682 1.81e-78 - - - S - - - macrophage migration inhibitory factor
GEPDGMEL_00683 1.85e-214 - - - C - - - Oxidoreductase
GEPDGMEL_00686 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
GEPDGMEL_00687 1.01e-190 - - - S - - - Calcineurin-like phosphoesterase
GEPDGMEL_00690 4.45e-143 - - - - - - - -
GEPDGMEL_00691 3.57e-316 - - - EGP - - - Major Facilitator
GEPDGMEL_00692 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
GEPDGMEL_00693 1.1e-171 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
GEPDGMEL_00694 3.54e-165 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
GEPDGMEL_00695 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GEPDGMEL_00696 1.58e-198 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GEPDGMEL_00697 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
GEPDGMEL_00698 1.65e-111 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
GEPDGMEL_00700 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
GEPDGMEL_00701 3.41e-231 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
GEPDGMEL_00702 0.0 - - - S - - - Bacterial membrane protein, YfhO
GEPDGMEL_00703 1.24e-171 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GEPDGMEL_00704 1.54e-216 - - - I - - - alpha/beta hydrolase fold
GEPDGMEL_00705 4.46e-276 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
GEPDGMEL_00706 3.36e-154 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GEPDGMEL_00707 3.52e-173 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GEPDGMEL_00708 4.28e-181 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
GEPDGMEL_00709 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
GEPDGMEL_00710 7.17e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GEPDGMEL_00711 1.93e-65 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
GEPDGMEL_00712 1.69e-129 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
GEPDGMEL_00713 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GEPDGMEL_00714 2.44e-265 yacL - - S - - - domain protein
GEPDGMEL_00715 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
GEPDGMEL_00716 8.79e-94 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GEPDGMEL_00717 6.35e-176 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GEPDGMEL_00718 3.63e-28 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
GEPDGMEL_00719 7.11e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GEPDGMEL_00720 1.81e-50 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
GEPDGMEL_00721 1.51e-237 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GEPDGMEL_00722 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GEPDGMEL_00723 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
GEPDGMEL_00724 1.05e-77 yloU - - S - - - Asp23 family, cell envelope-related function
GEPDGMEL_00725 1.1e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
GEPDGMEL_00726 8.12e-158 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
GEPDGMEL_00727 1.5e-149 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
GEPDGMEL_00728 1.03e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GEPDGMEL_00729 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
GEPDGMEL_00730 3.5e-167 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
GEPDGMEL_00731 2.31e-313 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GEPDGMEL_00732 4.98e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GEPDGMEL_00733 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GEPDGMEL_00734 1.17e-268 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GEPDGMEL_00735 6.66e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GEPDGMEL_00736 4.37e-148 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
GEPDGMEL_00737 7.4e-71 - - - - - - - -
GEPDGMEL_00738 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
GEPDGMEL_00739 2.25e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
GEPDGMEL_00740 9.79e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
GEPDGMEL_00741 2.49e-198 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GEPDGMEL_00742 2.83e-58 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GEPDGMEL_00743 1.09e-309 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GEPDGMEL_00744 1.88e-191 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GEPDGMEL_00745 2.24e-92 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GEPDGMEL_00746 1.32e-92 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
GEPDGMEL_00747 3.75e-142 - - - J - - - 2'-5' RNA ligase superfamily
GEPDGMEL_00748 4.13e-254 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
GEPDGMEL_00749 4.82e-164 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GEPDGMEL_00750 7.2e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
GEPDGMEL_00751 5.08e-72 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
GEPDGMEL_00752 2.68e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
GEPDGMEL_00753 1.63e-145 - - - K - - - Transcriptional regulator
GEPDGMEL_00756 1.93e-112 - - - S - - - Protein conserved in bacteria
GEPDGMEL_00757 1.03e-223 - - - - - - - -
GEPDGMEL_00758 4e-202 - - - - - - - -
GEPDGMEL_00759 4.41e-67 yitW - - S - - - Iron-sulfur cluster assembly protein
GEPDGMEL_00760 9.48e-130 msrA 1.8.4.11 - C ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GEPDGMEL_00761 4.82e-180 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
GEPDGMEL_00762 1.52e-167 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GEPDGMEL_00763 1.79e-101 - - - S - - - Flavodoxin
GEPDGMEL_00764 1.01e-83 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
GEPDGMEL_00765 9.9e-49 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
GEPDGMEL_00766 5.25e-279 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Transporter, major facilitator family protein
GEPDGMEL_00767 1.12e-211 - - - H - - - geranyltranstransferase activity
GEPDGMEL_00768 3.03e-231 - - - - - - - -
GEPDGMEL_00769 1.79e-25 - - - - - - - -
GEPDGMEL_00770 9.06e-151 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
GEPDGMEL_00771 6.46e-243 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
GEPDGMEL_00772 1.56e-60 - - - - - - - -
GEPDGMEL_00773 4.78e-135 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
GEPDGMEL_00774 2.28e-108 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
GEPDGMEL_00775 4.95e-288 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
GEPDGMEL_00776 6.2e-103 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
GEPDGMEL_00777 4.21e-242 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
GEPDGMEL_00778 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GEPDGMEL_00779 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
GEPDGMEL_00780 5.76e-128 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase molybdenum cofactor assembly chaperone
GEPDGMEL_00781 6.65e-168 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
GEPDGMEL_00782 4.24e-193 - - - EG - - - EamA-like transporter family
GEPDGMEL_00783 1.63e-152 - - - L - - - Integrase
GEPDGMEL_00784 1.03e-203 rssA - - S - - - Phospholipase, patatin family
GEPDGMEL_00785 1.16e-29 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
GEPDGMEL_00786 4.53e-110 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
GEPDGMEL_00787 1.56e-254 xerS - - L - - - Belongs to the 'phage' integrase family
GEPDGMEL_00789 2.41e-92 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GEPDGMEL_00790 9.21e-99 - - - K - - - Transcriptional regulator, MarR family
GEPDGMEL_00791 6.54e-90 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GEPDGMEL_00792 1.48e-64 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GEPDGMEL_00793 1.08e-13 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
GEPDGMEL_00794 4.6e-19 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
GEPDGMEL_00795 1.01e-189 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
GEPDGMEL_00796 1.23e-150 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
GEPDGMEL_00797 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
GEPDGMEL_00798 4.73e-102 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GEPDGMEL_00799 4.22e-121 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
GEPDGMEL_00800 3.75e-39 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
GEPDGMEL_00801 1.15e-24 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
GEPDGMEL_00802 5.3e-73 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
GEPDGMEL_00809 0.0 - - - L - - - PFAM plasmid pRiA4b ORF-3 family protein
GEPDGMEL_00810 3.86e-263 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
GEPDGMEL_00811 4.76e-143 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GEPDGMEL_00812 5.46e-207 mleR - - K - - - LysR family
GEPDGMEL_00813 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
GEPDGMEL_00814 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GEPDGMEL_00815 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GEPDGMEL_00816 6.01e-166 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GEPDGMEL_00817 6.12e-216 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
GEPDGMEL_00818 8.74e-158 citR - - K - - - sugar-binding domain protein
GEPDGMEL_00819 2.7e-222 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
GEPDGMEL_00820 3.28e-188 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GEPDGMEL_00821 4.97e-54 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
GEPDGMEL_00822 1.56e-202 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
GEPDGMEL_00823 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
GEPDGMEL_00824 5.47e-194 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
GEPDGMEL_00825 3.59e-143 - - - I - - - Alpha/beta hydrolase family
GEPDGMEL_00826 4.66e-201 - - - K - - - LysR family
GEPDGMEL_00827 0.0 - - - S - - - Putative threonine/serine exporter
GEPDGMEL_00828 5.46e-152 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
GEPDGMEL_00829 0.0 qacA - - EGP - - - Major Facilitator
GEPDGMEL_00830 4.54e-240 - - - I - - - Alpha beta
GEPDGMEL_00831 4.41e-131 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
GEPDGMEL_00832 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GEPDGMEL_00834 4.56e-210 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GEPDGMEL_00835 2.44e-20 - - - - - - - -
GEPDGMEL_00836 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GEPDGMEL_00837 0.0 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GEPDGMEL_00838 2.39e-226 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GEPDGMEL_00839 1.35e-200 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
GEPDGMEL_00840 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
GEPDGMEL_00841 2.52e-119 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GEPDGMEL_00842 3.09e-122 - - - - - - - -
GEPDGMEL_00844 5.93e-163 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GEPDGMEL_00845 4.08e-270 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
GEPDGMEL_00846 2.52e-148 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GEPDGMEL_00847 2.22e-46 ynzC - - S - - - UPF0291 protein
GEPDGMEL_00848 1.6e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
GEPDGMEL_00849 1.84e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
GEPDGMEL_00850 1.69e-181 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
GEPDGMEL_00851 1.32e-62 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
GEPDGMEL_00852 4.85e-232 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GEPDGMEL_00853 3.54e-184 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
GEPDGMEL_00854 3.14e-197 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GEPDGMEL_00855 1.81e-166 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
GEPDGMEL_00856 1.72e-122 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GEPDGMEL_00857 5.24e-182 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GEPDGMEL_00858 2.37e-177 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
GEPDGMEL_00859 1.15e-298 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
GEPDGMEL_00860 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GEPDGMEL_00861 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GEPDGMEL_00862 4.68e-233 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GEPDGMEL_00863 1.45e-280 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
GEPDGMEL_00864 1.29e-53 - - - S - - - Cytochrome B5
GEPDGMEL_00865 8.47e-08 - - - S - - - Cytochrome B5
GEPDGMEL_00866 9.37e-52 - - - S - - - Cytochrome B5
GEPDGMEL_00867 5.81e-96 - - - S ko:K02348 - ko00000 Gnat family
GEPDGMEL_00868 2e-14 - - - GM - - - NmrA-like family
GEPDGMEL_00869 5.32e-67 ydeP - - K - - - Transcriptional regulator, HxlR family
GEPDGMEL_00870 5.52e-139 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
GEPDGMEL_00871 2.25e-100 - - - K - - - Transcriptional regulator, HxlR family
GEPDGMEL_00872 3.32e-300 - - - - - - - -
GEPDGMEL_00873 1.32e-269 - - - EGP - - - Major Facilitator Superfamily
GEPDGMEL_00874 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
GEPDGMEL_00875 1.97e-143 - - - GM - - - NAD dependent epimerase dehydratase family protein
GEPDGMEL_00876 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
GEPDGMEL_00877 1.79e-119 - - - S - - - ECF transporter, substrate-specific component
GEPDGMEL_00878 1.43e-252 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
GEPDGMEL_00879 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
GEPDGMEL_00880 9.87e-167 - - - F - - - glutamine amidotransferase
GEPDGMEL_00881 3.12e-79 - - - - - - - -
GEPDGMEL_00882 2.6e-201 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
GEPDGMEL_00883 3.04e-199 - - - K - - - Transcriptional regulator
GEPDGMEL_00884 8.09e-235 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
GEPDGMEL_00885 1.11e-218 ypuA - - S - - - Protein of unknown function (DUF1002)
GEPDGMEL_00886 3.15e-115 - - - K - - - Virulence activator alpha C-term
GEPDGMEL_00887 3.29e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
GEPDGMEL_00888 2.04e-113 - - - C - - - Flavodoxin
GEPDGMEL_00889 2.99e-56 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
GEPDGMEL_00890 1.71e-132 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
GEPDGMEL_00891 1.92e-71 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
GEPDGMEL_00892 3.81e-140 flp - - V - - - Beta-lactamase
GEPDGMEL_00893 2.06e-188 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
GEPDGMEL_00894 2.17e-306 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
GEPDGMEL_00895 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
GEPDGMEL_00896 1.3e-82 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
GEPDGMEL_00897 1.54e-269 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GEPDGMEL_00898 3.12e-79 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GEPDGMEL_00899 7.36e-09 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
GEPDGMEL_00900 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GEPDGMEL_00901 8.69e-298 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
GEPDGMEL_00902 1e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GEPDGMEL_00903 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GEPDGMEL_00904 8.5e-213 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
GEPDGMEL_00905 0.0 - - - D - - - Domain of Unknown Function (DUF1542)
GEPDGMEL_00906 1.82e-195 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GEPDGMEL_00907 0.0 - - - G - - - Peptidase_C39 like family
GEPDGMEL_00908 9.19e-233 yueF - - S - - - AI-2E family transporter
GEPDGMEL_00909 1.53e-297 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GEPDGMEL_00910 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GEPDGMEL_00911 0.0 - - - M - - - NlpC/P60 family
GEPDGMEL_00912 2.76e-90 - - - S - - - Peptidase, M23
GEPDGMEL_00913 0.0 - - - S - - - Peptidase, M23
GEPDGMEL_00914 4.16e-85 - - - K - - - Transcriptional regulator, GntR family
GEPDGMEL_00915 1.06e-200 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GEPDGMEL_00916 2.85e-31 - - - - - - - -
GEPDGMEL_00917 2.57e-101 - - - - - - - -
GEPDGMEL_00918 9.48e-183 - - - G - - - MucBP domain
GEPDGMEL_00919 1.75e-127 - - - S - - - Pfam:DUF3816
GEPDGMEL_00920 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
GEPDGMEL_00921 5.62e-37 - - - - - - - -
GEPDGMEL_00922 3.69e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
GEPDGMEL_00923 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GEPDGMEL_00924 3.48e-288 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
GEPDGMEL_00925 3.25e-252 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
GEPDGMEL_00926 6.57e-229 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GEPDGMEL_00927 1.97e-53 - - - S - - - Protein of unknown function (DUF1797)
GEPDGMEL_00928 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GEPDGMEL_00929 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GEPDGMEL_00930 2.61e-204 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
GEPDGMEL_00931 4.93e-123 lemA - - S ko:K03744 - ko00000 LemA family
GEPDGMEL_00932 3.3e-113 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GEPDGMEL_00933 8.73e-154 - - - G - - - Belongs to the phosphoglycerate mutase family
GEPDGMEL_00934 1.59e-209 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
GEPDGMEL_00935 2.37e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GEPDGMEL_00936 2.48e-161 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
GEPDGMEL_00937 2.64e-212 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GEPDGMEL_00938 1.31e-302 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GEPDGMEL_00939 9.43e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
GEPDGMEL_00940 2.62e-300 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GEPDGMEL_00941 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GEPDGMEL_00942 1.04e-85 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GEPDGMEL_00943 9.28e-89 ywiB - - S - - - Domain of unknown function (DUF1934)
GEPDGMEL_00944 4.62e-186 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
GEPDGMEL_00945 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
GEPDGMEL_00946 4.65e-190 yidA - - S - - - hydrolase
GEPDGMEL_00947 2.58e-102 - - - - - - - -
GEPDGMEL_00948 9.36e-229 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GEPDGMEL_00949 3.17e-314 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GEPDGMEL_00950 5.24e-191 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
GEPDGMEL_00951 3.54e-165 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
GEPDGMEL_00952 9.8e-158 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
GEPDGMEL_00953 3.48e-216 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GEPDGMEL_00954 2.39e-139 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
GEPDGMEL_00955 8.57e-114 - - - - - - - -
GEPDGMEL_00956 9.3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
GEPDGMEL_00957 3.01e-274 yttB - - EGP - - - Major Facilitator
GEPDGMEL_00958 8.12e-144 - - - - - - - -
GEPDGMEL_00959 2.6e-33 - - - - - - - -
GEPDGMEL_00960 3.11e-220 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
GEPDGMEL_00961 0.0 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GEPDGMEL_00962 1.59e-65 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
GEPDGMEL_00963 2.79e-49 - - - - - - - -
GEPDGMEL_00964 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GEPDGMEL_00965 8.51e-148 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GEPDGMEL_00966 6.85e-234 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
GEPDGMEL_00967 1.52e-112 - - - K - - - transcriptional regulator (TetR family)
GEPDGMEL_00968 2.85e-243 - - - E - - - Zinc-binding dehydrogenase
GEPDGMEL_00969 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
GEPDGMEL_00970 2.81e-74 - - - - - - - -
GEPDGMEL_00971 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GEPDGMEL_00973 1.37e-41 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
GEPDGMEL_00974 3.08e-126 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
GEPDGMEL_00975 6.81e-47 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
GEPDGMEL_00976 1.93e-311 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
GEPDGMEL_00977 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GEPDGMEL_00978 2.57e-169 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GEPDGMEL_00979 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
GEPDGMEL_00980 1e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
GEPDGMEL_00981 5.52e-91 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
GEPDGMEL_00982 5.92e-235 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GEPDGMEL_00983 2.95e-303 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
GEPDGMEL_00984 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
GEPDGMEL_00985 2.1e-95 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
GEPDGMEL_00986 5.73e-216 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GEPDGMEL_00987 6.13e-233 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
GEPDGMEL_00988 7.1e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GEPDGMEL_00989 7.06e-79 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
GEPDGMEL_00990 2.1e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GEPDGMEL_00991 4.65e-184 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
GEPDGMEL_00992 2.14e-234 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
GEPDGMEL_00993 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
GEPDGMEL_00994 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GEPDGMEL_00995 5.98e-265 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GEPDGMEL_00996 5.91e-279 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GEPDGMEL_00997 3.4e-164 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
GEPDGMEL_00998 1.4e-196 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GEPDGMEL_00999 9.52e-303 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
GEPDGMEL_01000 1.11e-41 - - - S - - - Protein of unknown function (DUF2929)
GEPDGMEL_01001 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
GEPDGMEL_01002 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
GEPDGMEL_01003 5.36e-215 yitL - - S ko:K00243 - ko00000 S1 domain
GEPDGMEL_01004 1.36e-210 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
GEPDGMEL_01005 2.49e-84 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GEPDGMEL_01006 3.51e-180 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GEPDGMEL_01007 3.18e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GEPDGMEL_01008 3.66e-165 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GEPDGMEL_01009 1.08e-132 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GEPDGMEL_01010 2.84e-241 - - - S - - - Helix-turn-helix domain
GEPDGMEL_01011 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
GEPDGMEL_01012 1.31e-65 - - - M - - - Lysin motif
GEPDGMEL_01013 7.04e-149 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
GEPDGMEL_01014 1.49e-274 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
GEPDGMEL_01015 1.9e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
GEPDGMEL_01016 1.6e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GEPDGMEL_01017 9.5e-301 XK27_05225 - - S - - - Tetratricopeptide repeat protein
GEPDGMEL_01018 3.33e-285 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GEPDGMEL_01019 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
GEPDGMEL_01020 2.44e-245 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GEPDGMEL_01021 2.67e-116 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GEPDGMEL_01022 3.53e-142 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
GEPDGMEL_01023 9.07e-196 WQ51_01275 - - S - - - EDD domain protein, DegV family
GEPDGMEL_01024 1.37e-220 - - - E - - - lipolytic protein G-D-S-L family
GEPDGMEL_01025 4.05e-141 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
GEPDGMEL_01026 1.33e-47 yozE - - S - - - Belongs to the UPF0346 family
GEPDGMEL_01027 1.71e-205 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GEPDGMEL_01028 1.44e-180 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GEPDGMEL_01029 6.71e-208 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
GEPDGMEL_01030 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GEPDGMEL_01031 3.08e-209 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
GEPDGMEL_01032 1.56e-138 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GEPDGMEL_01033 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GEPDGMEL_01034 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GEPDGMEL_01035 4.2e-110 - - - F - - - Hydrolase, NUDIX family
GEPDGMEL_01036 2.57e-222 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
GEPDGMEL_01037 3.67e-89 - - - S - - - Belongs to the HesB IscA family
GEPDGMEL_01038 5.5e-67 - - - - - - - -
GEPDGMEL_01040 3.93e-119 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
GEPDGMEL_01041 4.49e-80 asp1 - - S - - - Asp23 family, cell envelope-related function
GEPDGMEL_01042 3.09e-35 - - - - - - - -
GEPDGMEL_01043 3.97e-125 - - - - - - - -
GEPDGMEL_01044 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
GEPDGMEL_01045 2.06e-49 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
GEPDGMEL_01046 4.86e-100 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
GEPDGMEL_01047 1.21e-280 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
GEPDGMEL_01048 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
GEPDGMEL_01049 3.42e-124 - - - K - - - Acetyltransferase (GNAT) domain
GEPDGMEL_01050 7.67e-63 - - - - - - - -
GEPDGMEL_01051 1.05e-40 - - - - - - - -
GEPDGMEL_01052 1.26e-60 - - - - - - - -
GEPDGMEL_01053 4.03e-98 - - - S - - - Protein of unknown function (DUF805)
GEPDGMEL_01054 6.73e-44 - - - S - - - Uncharacterised protein family (UPF0236)
GEPDGMEL_01055 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 chorismate binding enzyme
GEPDGMEL_01056 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GEPDGMEL_01057 3.06e-198 menH 4.2.99.20 - I ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
GEPDGMEL_01058 7.73e-260 - - - G - - - Major Facilitator Superfamily
GEPDGMEL_01059 2.51e-261 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GEPDGMEL_01060 1.02e-294 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
GEPDGMEL_01061 2.76e-103 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GEPDGMEL_01062 1.6e-163 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
GEPDGMEL_01063 1.67e-136 yocS - - S ko:K03453 - ko00000 SBF-like CPA transporter family (DUF4137)
GEPDGMEL_01064 3.51e-119 isp - - L - - - Transposase
GEPDGMEL_01065 3.85e-95 mrr2 - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
GEPDGMEL_01067 6.57e-21 - - - - - - - -
GEPDGMEL_01068 2.57e-135 - - - L - - - PLD-like domain
GEPDGMEL_01069 0.0 - - - L - - - PLD-like domain
GEPDGMEL_01071 5.22e-228 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
GEPDGMEL_01072 3.46e-243 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GEPDGMEL_01073 1.18e-124 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
GEPDGMEL_01074 5.32e-286 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
GEPDGMEL_01075 2.62e-100 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
GEPDGMEL_01076 3.5e-144 - - - T ko:K10716 - ko00000,ko02000 Ion transport 2 domain protein
GEPDGMEL_01077 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
GEPDGMEL_01078 1.82e-255 - - - G - - - Transporter, major facilitator family protein
GEPDGMEL_01079 8.27e-141 - - - K ko:K03091 - ko00000,ko03021 RNA polymerase sigma factor, sigma-70 family
GEPDGMEL_01080 4.73e-85 yuxO - - Q - - - Thioesterase superfamily
GEPDGMEL_01081 8.13e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GEPDGMEL_01082 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
GEPDGMEL_01083 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
GEPDGMEL_01084 2.32e-43 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
GEPDGMEL_01085 5.43e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
GEPDGMEL_01086 1.66e-305 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
GEPDGMEL_01087 9.47e-301 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GEPDGMEL_01088 2.61e-105 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
GEPDGMEL_01089 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
GEPDGMEL_01090 2.79e-75 - - - S - - - Iron-sulfur cluster assembly protein
GEPDGMEL_01091 1.11e-204 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
GEPDGMEL_01092 1.14e-144 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
GEPDGMEL_01093 1.43e-51 - - - S - - - Cytochrome B5
GEPDGMEL_01094 2.62e-199 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
GEPDGMEL_01095 3.32e-305 - - - M - - - family 8
GEPDGMEL_01096 2.6e-259 - - - L - - - Transposase
GEPDGMEL_01097 2.39e-80 - - - M - - - family 8
GEPDGMEL_01098 2.15e-138 - - - M - - - transferase activity, transferring glycosyl groups
GEPDGMEL_01099 1.77e-205 secY2 - - U - - - Part of the accessory SecA2 SecY2 system specifically required for export of
GEPDGMEL_01100 2.1e-247 - - - M - - - transferase activity, transferring glycosyl groups
GEPDGMEL_01101 1.43e-268 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system GspB-transporter
GEPDGMEL_01102 3.67e-198 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec secretory system ASP3
GEPDGMEL_01103 0.0 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GEPDGMEL_01104 2.01e-286 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
GEPDGMEL_01105 3.53e-243 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
GEPDGMEL_01110 5.79e-79 - - - L - - - Resolvase, N terminal domain
GEPDGMEL_01114 1.85e-12 - - - - - - - -
GEPDGMEL_01117 5.19e-09 - - - K - - - Helix-turn-helix XRE-family like proteins
GEPDGMEL_01119 7.69e-207 - - - - - - - -
GEPDGMEL_01120 2.25e-07 - - - K - - - Helix-turn-helix XRE-family like proteins
GEPDGMEL_01122 2.7e-200 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
GEPDGMEL_01123 5.82e-61 - - - - - - - -
GEPDGMEL_01131 0.000186 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
GEPDGMEL_01132 4.11e-85 - - - K - - - Bacterial regulatory proteins, tetR family
GEPDGMEL_01133 1.29e-104 - - - S - - - NADPH-dependent FMN reductase
GEPDGMEL_01134 6.25e-51 - - - S - - - Protein of unknown function (DUF3021)
GEPDGMEL_01135 1.56e-31 - - - - - - - -
GEPDGMEL_01136 6.13e-27 - - - - - - - -
GEPDGMEL_01137 3.78e-23 - - - - - - - -
GEPDGMEL_01138 5.67e-70 - - - S - - - Belongs to the HesB IscA family
GEPDGMEL_01139 2.94e-59 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GEPDGMEL_01140 4.46e-67 - - - K - - - Bacterial regulatory proteins, tetR family
GEPDGMEL_01141 4.28e-92 - - - S - - - NADPH-dependent FMN reductase
GEPDGMEL_01143 2.37e-224 - - - L - - - Plasmid pRiA4b ORF-3-like protein
GEPDGMEL_01145 1.39e-79 - - - S - - - Protein of unknown function (DUF3021)
GEPDGMEL_01146 8.81e-98 - - - K - - - LytTr DNA-binding domain
GEPDGMEL_01147 9.64e-188 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
GEPDGMEL_01148 4.16e-198 - - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GEPDGMEL_01149 6.57e-63 - - - - - - - -
GEPDGMEL_01151 1.35e-117 - - - S - - - PD-(D/E)XK nuclease family transposase
GEPDGMEL_01152 1.75e-311 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
GEPDGMEL_01153 3.95e-115 - - - - - - - -
GEPDGMEL_01154 1.4e-154 pnb - - C - - - nitroreductase
GEPDGMEL_01155 7.09e-39 XK27_00915 - - C - - - Luciferase-like monooxygenase
GEPDGMEL_01156 5.19e-186 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
GEPDGMEL_01157 5.29e-89 - - - S - - - Protein of unknown function (DUF3021)
GEPDGMEL_01158 1.81e-94 - - - K - - - LytTr DNA-binding domain
GEPDGMEL_01159 0.0 - - - S - - - Putative peptidoglycan binding domain
GEPDGMEL_01160 7.85e-21 - - - - - - - -
GEPDGMEL_01161 6.67e-158 - - - M - - - ErfK YbiS YcfS YnhG
GEPDGMEL_01163 9.2e-130 - - - - - - - -
GEPDGMEL_01164 2.68e-275 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GEPDGMEL_01165 4.94e-186 - - - S - - - Alpha beta hydrolase
GEPDGMEL_01166 3.46e-265 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
GEPDGMEL_01167 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GEPDGMEL_01168 1.4e-53 - - - - - - - -
GEPDGMEL_01169 9.13e-160 pgm3 - - G - - - phosphoglycerate mutase family
GEPDGMEL_01170 0.0 - - - S - - - C4-dicarboxylate anaerobic carrier
GEPDGMEL_01171 8.86e-317 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
GEPDGMEL_01172 5.58e-306 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
GEPDGMEL_01173 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GEPDGMEL_01174 8.21e-216 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
GEPDGMEL_01175 1.6e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
GEPDGMEL_01176 3.78e-169 yceF - - P ko:K05794 - ko00000 membrane
GEPDGMEL_01177 2.54e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
GEPDGMEL_01178 4.13e-147 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
GEPDGMEL_01180 8.19e-70 - - - S - - - GyrI-like small molecule binding domain
GEPDGMEL_01181 2.35e-22 - - - S - - - GyrI-like small molecule binding domain
GEPDGMEL_01182 2.21e-155 - - - S ko:K07507 - ko00000,ko02000 MgtC family
GEPDGMEL_01183 8.35e-119 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
GEPDGMEL_01184 7.88e-245 flp - - V - - - Beta-lactamase
GEPDGMEL_01185 8.48e-96 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GEPDGMEL_01186 6.03e-114 - - - J ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
GEPDGMEL_01187 3.56e-27 - - - L - - - Addiction module antitoxin, RelB DinJ family
GEPDGMEL_01188 9.98e-24 - - - - - - - -
GEPDGMEL_01189 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GEPDGMEL_01190 5.09e-153 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
GEPDGMEL_01191 2.25e-163 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
GEPDGMEL_01194 4.39e-12 - - - S - - - Bacteriocin class II with double-glycine leader peptide
GEPDGMEL_01196 7.05e-56 - - - S ko:K07088 - ko00000 Membrane transport protein
GEPDGMEL_01197 2.13e-158 - - - T - - - Transcriptional regulatory protein, C terminal
GEPDGMEL_01198 2.4e-312 - - - T - - - GHKL domain
GEPDGMEL_01199 1.38e-140 - - - S - - - Peptidase propeptide and YPEB domain
GEPDGMEL_01200 4.97e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
GEPDGMEL_01201 6.01e-260 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
GEPDGMEL_01202 4.77e-57 - - - S - - - Glycosyltransferase like family 2
GEPDGMEL_01203 8.23e-32 - - - M - - - Glycosyltransferase, group 2 family protein
GEPDGMEL_01204 1.78e-36 - - - M - - - PFAM Glycosyl transferase family 2
GEPDGMEL_01205 1.11e-32 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
GEPDGMEL_01206 2.17e-84 cps2I - - S - - - Psort location CytoplasmicMembrane, score
GEPDGMEL_01208 2.24e-49 - - - M - - - Glycosyltransferase GT-D fold
GEPDGMEL_01209 3.33e-81 wefC - - M - - - Stealth protein CR2, conserved region 2
GEPDGMEL_01210 4.29e-104 - - GT4 G ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like domain
GEPDGMEL_01211 9.95e-63 capM - - M ko:K13012 - ko00000,ko01005 Bacterial sugar transferase
GEPDGMEL_01212 3.01e-140 ywqD - - D - - - Capsular exopolysaccharide family
GEPDGMEL_01213 1.86e-127 epsB - - M - - - biosynthesis protein
GEPDGMEL_01214 8.71e-259 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GEPDGMEL_01215 1.9e-203 cudT - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
GEPDGMEL_01216 1.11e-108 - - - M - - - MobA-like NTP transferase domain
GEPDGMEL_01217 4.76e-230 - - - M - - - MobA-like NTP transferase domain
GEPDGMEL_01218 6.27e-129 - - - O - - - Bacterial dnaA protein
GEPDGMEL_01219 9.17e-50 - - - L - - - Integrase core domain
GEPDGMEL_01220 6.19e-104 - - - L - - - Integrase core domain
GEPDGMEL_01222 3.45e-88 - - - K - - - Bacterial regulatory proteins, tetR family
GEPDGMEL_01223 9.67e-49 - - - S - - - Domain of unknown function (DUF4440)
GEPDGMEL_01224 3.1e-256 qacA - - EGP - - - Fungal trichothecene efflux pump (TRI12)
GEPDGMEL_01225 5.16e-53 - - - S - - - Hexapeptide repeat of succinyl-transferase
GEPDGMEL_01226 3.11e-159 - - - C - - - Aldo keto reductase
GEPDGMEL_01227 8.03e-113 - - - GM - - - NAD(P)H-binding
GEPDGMEL_01228 1.23e-175 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
GEPDGMEL_01229 8.14e-239 - - - L ko:K07482 - ko00000 Helix-turn-helix domain
GEPDGMEL_01230 1.9e-147 - - - S ko:K07118 - ko00000 NAD(P)H-binding
GEPDGMEL_01231 2.3e-52 - - - S - - - Cytochrome b5-like Heme/Steroid binding domain
GEPDGMEL_01232 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
GEPDGMEL_01233 5.64e-232 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GEPDGMEL_01235 3.55e-132 - - - S ko:K07002 - ko00000 Serine hydrolase
GEPDGMEL_01236 1.26e-82 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
GEPDGMEL_01237 5.87e-180 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GEPDGMEL_01239 9.77e-230 ydhF - - S - - - Aldo keto reductase
GEPDGMEL_01240 9.58e-112 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 PAP2 superfamily
GEPDGMEL_01241 0.0 - - - L - - - Helicase C-terminal domain protein
GEPDGMEL_01243 4.78e-105 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GEPDGMEL_01244 2.59e-277 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GEPDGMEL_01245 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GEPDGMEL_01246 4.3e-169 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
GEPDGMEL_01247 7.21e-47 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GEPDGMEL_01248 1.9e-161 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GEPDGMEL_01249 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GEPDGMEL_01250 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GEPDGMEL_01251 6.44e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
GEPDGMEL_01252 4.78e-135 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GEPDGMEL_01253 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
GEPDGMEL_01254 1.12e-307 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
GEPDGMEL_01255 5.27e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GEPDGMEL_01256 1.94e-227 - - - - - - - -
GEPDGMEL_01257 5.99e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GEPDGMEL_01258 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
GEPDGMEL_01259 6.79e-182 - - - S - - - DUF218 domain
GEPDGMEL_01260 2.79e-89 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GEPDGMEL_01261 7.52e-78 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GEPDGMEL_01262 5.16e-72 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GEPDGMEL_01263 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
GEPDGMEL_01264 5.85e-158 - - - S - - - SNARE associated Golgi protein
GEPDGMEL_01265 1.09e-292 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
GEPDGMEL_01266 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GEPDGMEL_01268 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
GEPDGMEL_01269 1.34e-199 endA - - V ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
GEPDGMEL_01270 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GEPDGMEL_01271 4.12e-56 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
GEPDGMEL_01272 5.44e-109 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
GEPDGMEL_01273 5.61e-273 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
GEPDGMEL_01274 1.29e-58 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
GEPDGMEL_01275 1.96e-65 ylxQ - - J - - - ribosomal protein
GEPDGMEL_01276 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GEPDGMEL_01277 1.38e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GEPDGMEL_01278 9.98e-215 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GEPDGMEL_01279 6.06e-223 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
GEPDGMEL_01280 1.26e-84 - - - - - - - -
GEPDGMEL_01281 4.58e-247 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GEPDGMEL_01282 8.1e-118 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GEPDGMEL_01283 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
GEPDGMEL_01284 5.41e-274 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GEPDGMEL_01285 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GEPDGMEL_01286 3.7e-176 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
GEPDGMEL_01287 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
GEPDGMEL_01288 1.76e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
GEPDGMEL_01289 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
GEPDGMEL_01290 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
GEPDGMEL_01291 7.05e-270 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
GEPDGMEL_01292 3e-221 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
GEPDGMEL_01293 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
GEPDGMEL_01294 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GEPDGMEL_01295 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GEPDGMEL_01296 4.76e-137 - - - K - - - PFAM GCN5-related N-acetyltransferase
GEPDGMEL_01298 2.53e-209 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
GEPDGMEL_01299 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
GEPDGMEL_01300 8.68e-44 - - - - - - - -
GEPDGMEL_01301 1.88e-271 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GEPDGMEL_01302 8.8e-185 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GEPDGMEL_01303 5.64e-97 - - - O - - - OsmC-like protein
GEPDGMEL_01305 3.1e-306 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GEPDGMEL_01309 8.89e-170 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
GEPDGMEL_01310 4.2e-200 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
GEPDGMEL_01315 0.0 - - - S - - - Putative peptidoglycan binding domain
GEPDGMEL_01316 1.08e-66 - - - - - - - -
GEPDGMEL_01317 7.42e-277 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
GEPDGMEL_01318 1.39e-166 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
GEPDGMEL_01319 2.03e-200 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GEPDGMEL_01320 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GEPDGMEL_01321 2.91e-187 - 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GEPDGMEL_01322 1.46e-190 - - - E - - - Glyoxalase-like domain
GEPDGMEL_01323 8.4e-200 - - - U ko:K05340 - ko00000,ko02000 sugar transport
GEPDGMEL_01324 1.08e-288 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
GEPDGMEL_01325 1.1e-125 - - - S - - - reductase
GEPDGMEL_01326 2.63e-115 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GEPDGMEL_01327 2.08e-26 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
GEPDGMEL_01328 5.79e-117 pgpA - - I - - - Phosphatidylglycerophosphatase A
GEPDGMEL_01329 4.08e-288 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
GEPDGMEL_01330 1.46e-195 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
GEPDGMEL_01331 7.14e-193 yycI - - S - - - YycH protein
GEPDGMEL_01332 2.89e-316 yycH - - S - - - YycH protein
GEPDGMEL_01333 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GEPDGMEL_01334 2.6e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
GEPDGMEL_01336 1.61e-205 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
GEPDGMEL_01337 4.95e-58 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
GEPDGMEL_01338 5.18e-94 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
GEPDGMEL_01340 7.88e-158 - - - S - - - Fic/DOC family
GEPDGMEL_01341 3.6e-208 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
GEPDGMEL_01342 1.62e-312 aldA 1.2.1.21, 1.2.1.22 - C ko:K07248 ko00620,ko00630,ko01120,map00620,map00630,map01120 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family
GEPDGMEL_01343 3.79e-251 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
GEPDGMEL_01344 9.43e-73 - - - - - - - -
GEPDGMEL_01345 6.51e-270 yttB - - EGP - - - Major Facilitator
GEPDGMEL_01346 3.65e-308 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
GEPDGMEL_01347 1.25e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
GEPDGMEL_01348 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
GEPDGMEL_01349 9.36e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GEPDGMEL_01350 2.82e-112 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GEPDGMEL_01351 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
GEPDGMEL_01352 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GEPDGMEL_01353 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GEPDGMEL_01354 1.7e-261 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GEPDGMEL_01355 5.41e-47 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
GEPDGMEL_01356 3.31e-262 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GEPDGMEL_01357 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GEPDGMEL_01358 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
GEPDGMEL_01359 1.39e-76 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GEPDGMEL_01360 8.5e-172 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GEPDGMEL_01361 6.26e-170 jag - - S ko:K06346 - ko00000 R3H domain protein
GEPDGMEL_01362 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GEPDGMEL_01363 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GEPDGMEL_01364 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
GEPDGMEL_01365 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GEPDGMEL_01366 4.26e-314 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
GEPDGMEL_01367 2.44e-147 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GEPDGMEL_01368 9.23e-116 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase, GNAT family
GEPDGMEL_01369 9.53e-206 - - - S - - - reductase
GEPDGMEL_01371 1.57e-10 - - - S - - - Protein of unknown function (DUF1211)
GEPDGMEL_01372 0.000336 - - - S - - - Protein of unknown function (DUF1211)
GEPDGMEL_01373 1.67e-45 - - - K - - - LysR substrate binding domain
GEPDGMEL_01375 7.33e-63 - - - S - - - amidohydrolase
GEPDGMEL_01376 8.61e-291 - - - S - - - amidohydrolase
GEPDGMEL_01377 5.94e-94 - - - L - - - Integrase core domain
GEPDGMEL_01378 1.45e-233 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
GEPDGMEL_01379 1.62e-229 - - - - - - - -
GEPDGMEL_01380 3.79e-101 - - - - - - - -
GEPDGMEL_01381 1.09e-144 - - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
GEPDGMEL_01382 0.0 - - - S - - - SEC-C Motif Domain Protein
GEPDGMEL_01383 1.02e-66 - - - - - - - -
GEPDGMEL_01384 2.65e-178 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GEPDGMEL_01385 3.39e-187 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
GEPDGMEL_01386 6.39e-150 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
GEPDGMEL_01387 3.39e-293 - - - P - - - Chloride transporter, ClC family
GEPDGMEL_01388 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
GEPDGMEL_01389 5.65e-143 - - - I - - - Acid phosphatase homologues
GEPDGMEL_01391 5.11e-120 - - - - - - - -
GEPDGMEL_01392 1.2e-76 - - - - - - - -
GEPDGMEL_01393 9.95e-36 - - - - - - - -
GEPDGMEL_01394 1.68e-190 - - - G - - - Belongs to the phosphoglycerate mutase family
GEPDGMEL_01395 1.32e-156 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GEPDGMEL_01396 1.18e-134 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
GEPDGMEL_01397 3.03e-91 - - - - - - - -
GEPDGMEL_01398 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GEPDGMEL_01399 1.24e-136 - - - L - - - nuclease
GEPDGMEL_01400 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
GEPDGMEL_01401 2.25e-265 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GEPDGMEL_01402 3.38e-27 - - - L - - - Integrase core domain
GEPDGMEL_01403 2.95e-50 - - - K - - - NAD+ binding
GEPDGMEL_01404 8.39e-217 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
GEPDGMEL_01405 5.26e-211 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
GEPDGMEL_01406 3.6e-215 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
GEPDGMEL_01407 1.46e-35 - - - K - - - Cro/C1-type HTH DNA-binding domain
GEPDGMEL_01408 4.25e-98 - - - L - - - ATPase involved in DNA repair
GEPDGMEL_01410 2.7e-37 - - - - - - - -
GEPDGMEL_01412 2.01e-35 - - - - - - - -
GEPDGMEL_01413 4.79e-27 - - - - - - - -
GEPDGMEL_01414 5.57e-09 - - - S - - - Bacteriophage holin family
GEPDGMEL_01415 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GEPDGMEL_01416 3.03e-256 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
GEPDGMEL_01417 3.37e-222 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GEPDGMEL_01418 6.77e-77 - - - - - - - -
GEPDGMEL_01419 8.04e-230 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
GEPDGMEL_01420 5.13e-162 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GEPDGMEL_01421 5.61e-71 - - - - - - - -
GEPDGMEL_01422 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GEPDGMEL_01423 1.88e-101 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GEPDGMEL_01424 0.0 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GEPDGMEL_01425 3.1e-213 - - - G - - - Phosphotransferase enzyme family
GEPDGMEL_01426 2e-70 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GEPDGMEL_01427 6.78e-81 - - - S - - - Protein of unknown function (DUF1700)
GEPDGMEL_01428 5.39e-64 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
GEPDGMEL_01429 1.43e-67 entB - - Q - - - Isochorismatase family
GEPDGMEL_01430 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
GEPDGMEL_01431 2.08e-239 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GEPDGMEL_01432 9.26e-218 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GEPDGMEL_01433 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GEPDGMEL_01434 3.68e-125 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
GEPDGMEL_01435 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GEPDGMEL_01436 5.75e-103 yabR - - J ko:K07571 - ko00000 RNA binding
GEPDGMEL_01437 5.74e-177 wchF - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
GEPDGMEL_01438 4.97e-142 - - - M - - - Glycosyltransferase Family 4
GEPDGMEL_01439 2.88e-134 cps2G - - M - - - Stealth protein CR2, conserved region 2
GEPDGMEL_01440 2.2e-60 - - - M - - - Glycosyltransferase
GEPDGMEL_01441 4.54e-199 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 UDP-N-acetylglucosamine 2-epimerase
GEPDGMEL_01442 2.82e-83 - - - M - - - transferase activity, transferring glycosyl groups
GEPDGMEL_01444 2.79e-173 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
GEPDGMEL_01445 1.74e-83 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
GEPDGMEL_01446 3.24e-54 - - - M ko:K07271 - ko00000,ko01000 LicD family
GEPDGMEL_01447 1.42e-142 - - - L ko:K07497 - ko00000 hmm pf00665
GEPDGMEL_01448 0.0 - 2.4.1.5 GH13 G ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
GEPDGMEL_01449 0.0 - 2.4.1.5 GH13 G ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
GEPDGMEL_01450 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GEPDGMEL_01451 6.36e-277 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
GEPDGMEL_01452 2.31e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GEPDGMEL_01453 2.47e-101 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
GEPDGMEL_01455 3.96e-178 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GEPDGMEL_01456 0.0 yhaN - - L - - - AAA domain
GEPDGMEL_01457 7.06e-271 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
GEPDGMEL_01458 1.4e-63 yheA - - S - - - Belongs to the UPF0342 family
GEPDGMEL_01459 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GEPDGMEL_01460 4.11e-223 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GEPDGMEL_01461 1.46e-196 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GEPDGMEL_01462 1.29e-150 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
GEPDGMEL_01463 2.41e-148 yjbH - - Q - - - Thioredoxin
GEPDGMEL_01464 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GEPDGMEL_01465 5.93e-265 coiA - - S ko:K06198 - ko00000 Competence protein
GEPDGMEL_01466 9.02e-154 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GEPDGMEL_01467 2.02e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GEPDGMEL_01468 3.75e-103 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
GEPDGMEL_01489 1.57e-94 - - - S - - - Metallo-beta-lactamase superfamily
GEPDGMEL_01490 3.58e-37 - - - K - - - Psort location Cytoplasmic, score
GEPDGMEL_01491 1.42e-31 - - - K - - - Psort location Cytoplasmic, score
GEPDGMEL_01492 1.7e-67 yjdF3 - - S - - - Protein of unknown function (DUF2992)
GEPDGMEL_01493 8.74e-74 - - - L - - - Transposase
GEPDGMEL_01494 4.15e-150 isp - - L - - - Transposase
GEPDGMEL_01495 1.56e-96 - 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Asp/Glu/Hydantoin racemase
GEPDGMEL_01496 4.43e-43 - 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Asp/Glu/Hydantoin racemase
GEPDGMEL_01497 5.16e-146 ung2 - - L - - - Uracil-DNA glycosylase
GEPDGMEL_01498 3.96e-145 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
GEPDGMEL_01499 1.09e-122 dpsB - - P - - - Belongs to the Dps family
GEPDGMEL_01500 2.25e-45 - - - C - - - Heavy-metal-associated domain
GEPDGMEL_01501 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
GEPDGMEL_01502 1.76e-133 - - - - - - - -
GEPDGMEL_01504 3.25e-252 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
GEPDGMEL_01505 1.21e-207 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
GEPDGMEL_01506 2.17e-123 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GEPDGMEL_01507 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
GEPDGMEL_01508 4.47e-16 - - - S - - - Protein of unknown function (DUF4044)
GEPDGMEL_01509 8.07e-76 - - - - - - - -
GEPDGMEL_01510 8.67e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
GEPDGMEL_01511 2.29e-224 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GEPDGMEL_01512 5.99e-74 ftsL - - D - - - Cell division protein FtsL
GEPDGMEL_01513 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GEPDGMEL_01514 1.56e-229 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GEPDGMEL_01515 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GEPDGMEL_01516 3.99e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GEPDGMEL_01517 1.73e-185 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GEPDGMEL_01518 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GEPDGMEL_01519 6.52e-289 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GEPDGMEL_01520 1.11e-92 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GEPDGMEL_01521 1.11e-54 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
GEPDGMEL_01522 1.06e-189 ylmH - - S - - - S4 domain protein
GEPDGMEL_01523 3.71e-109 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
GEPDGMEL_01524 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GEPDGMEL_01525 5.69e-44 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
GEPDGMEL_01526 2.48e-129 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
GEPDGMEL_01527 1.54e-33 - - - - - - - -
GEPDGMEL_01528 3.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GEPDGMEL_01529 5.23e-277 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
GEPDGMEL_01530 2.27e-75 XK27_04120 - - S - - - Putative amino acid metabolism
GEPDGMEL_01531 1.25e-285 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GEPDGMEL_01532 1.15e-158 pgm6 - - G - - - phosphoglycerate mutase
GEPDGMEL_01533 3.82e-157 - - - S - - - repeat protein
GEPDGMEL_01534 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GEPDGMEL_01535 1.48e-223 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GEPDGMEL_01536 3.08e-241 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GEPDGMEL_01537 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GEPDGMEL_01538 5.72e-316 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GEPDGMEL_01539 2.66e-111 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GEPDGMEL_01540 5.47e-282 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GEPDGMEL_01541 9.32e-223 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GEPDGMEL_01542 4.46e-181 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GEPDGMEL_01543 2.3e-276 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GEPDGMEL_01544 1.82e-254 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GEPDGMEL_01545 2.07e-262 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
GEPDGMEL_01546 1.25e-74 - - - - - - - -
GEPDGMEL_01548 3.71e-234 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
GEPDGMEL_01549 1.47e-37 - - - - - - - -
GEPDGMEL_01550 7.16e-231 - - - I - - - Diacylglycerol kinase catalytic
GEPDGMEL_01551 9.99e-44 ykzG - - S - - - Belongs to the UPF0356 family
GEPDGMEL_01552 2.79e-107 - - - - - - - -
GEPDGMEL_01553 1.68e-133 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GEPDGMEL_01554 9.95e-267 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
GEPDGMEL_01555 9.42e-232 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
GEPDGMEL_01556 1.06e-311 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GEPDGMEL_01557 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
GEPDGMEL_01558 1.17e-61 yktA - - S - - - Belongs to the UPF0223 family
GEPDGMEL_01559 4.1e-176 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
GEPDGMEL_01560 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
GEPDGMEL_01561 1.85e-284 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
GEPDGMEL_01562 5.05e-57 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
GEPDGMEL_01563 3.23e-127 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
GEPDGMEL_01564 3.05e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GEPDGMEL_01565 3.14e-254 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
GEPDGMEL_01566 1.97e-137 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
GEPDGMEL_01567 7.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
GEPDGMEL_01568 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
GEPDGMEL_01569 5.37e-192 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
GEPDGMEL_01570 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
GEPDGMEL_01571 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GEPDGMEL_01572 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GEPDGMEL_01573 2.32e-204 - - - S - - - Tetratricopeptide repeat
GEPDGMEL_01574 4.94e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GEPDGMEL_01575 5.54e-303 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GEPDGMEL_01576 1.19e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GEPDGMEL_01577 2.01e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
GEPDGMEL_01578 1.11e-78 - - - S - - - mazG nucleotide pyrophosphohydrolase
GEPDGMEL_01579 0.0 - - - O - - - Arylsulfotransferase (ASST)
GEPDGMEL_01580 0.0 - - - L - - - Transposase
GEPDGMEL_01581 1.3e-262 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
GEPDGMEL_01582 2.06e-278 - - - G - - - Transporter, major facilitator family protein
GEPDGMEL_01583 3.16e-313 - - - E - - - Peptidase family M20/M25/M40
GEPDGMEL_01584 4.09e-196 - - - K - - - Transcriptional regulator, LysR family
GEPDGMEL_01586 4.2e-88 - - - T ko:K07171 - ko00000,ko01000,ko02048 Toxin-antitoxin system, toxin component, MazF family
GEPDGMEL_01587 4.74e-51 - - - - ko:K18829 - ko00000,ko02048 -
GEPDGMEL_01589 0.0 snf - - KL - - - domain protein
GEPDGMEL_01590 1.44e-185 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
GEPDGMEL_01593 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GEPDGMEL_01594 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
GEPDGMEL_01595 1.89e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
GEPDGMEL_01596 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GEPDGMEL_01597 9.52e-108 - - - - - - - -
GEPDGMEL_01598 3.96e-49 - - - - - - - -
GEPDGMEL_01599 1.13e-81 - - - K - - - DNA-templated transcription, initiation
GEPDGMEL_01600 3.38e-26 - - - - - - - -
GEPDGMEL_01601 1.31e-152 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
GEPDGMEL_01602 4.19e-101 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K07000,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
GEPDGMEL_01603 8.12e-243 - - - S - - - Protein of unknown function (DUF3114)
GEPDGMEL_01604 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
GEPDGMEL_01605 1.31e-213 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
GEPDGMEL_01606 2.83e-133 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
GEPDGMEL_01607 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
GEPDGMEL_01608 8.72e-53 - - - - - - - -
GEPDGMEL_01609 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GEPDGMEL_01610 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GEPDGMEL_01611 8.69e-76 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
GEPDGMEL_01612 1.01e-52 yabO - - J - - - S4 domain protein
GEPDGMEL_01613 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GEPDGMEL_01614 5.62e-132 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GEPDGMEL_01615 1.9e-145 - - - S - - - (CBS) domain
GEPDGMEL_01616 9.04e-56 - - - K - - - HxlR-like helix-turn-helix
GEPDGMEL_01617 3.3e-91 M1-798 - - K - - - Rhodanese Homology Domain
GEPDGMEL_01618 2.9e-33 - - - CO ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 cell redox homeostasis
GEPDGMEL_01619 8.86e-177 trxB 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Glucose inhibited division protein A
GEPDGMEL_01620 1.01e-122 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 dithiol-disulfide isomerase involved in polyketide biosynthesis
GEPDGMEL_01622 3.92e-52 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
GEPDGMEL_01623 7.72e-49 ytpP - - CO - - - Thioredoxin
GEPDGMEL_01624 2.24e-218 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GEPDGMEL_01625 1.75e-180 epsB - - M - - - biosynthesis protein
GEPDGMEL_01626 9.25e-152 ywqD - - D - - - Capsular exopolysaccharide family
GEPDGMEL_01627 1.31e-136 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
GEPDGMEL_01628 1.65e-205 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GEPDGMEL_01630 3.44e-60 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 transmembrane transport
GEPDGMEL_01631 7.79e-89 ysdB - - S ko:K01990 - ko00000,ko00002,ko02000 Domain of unknown function (DUF4162)
GEPDGMEL_01632 7.3e-125 - - - L - - - Transposase
GEPDGMEL_01633 3.08e-26 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
GEPDGMEL_01634 1.87e-74 - - - S - - - Pfam:DUF59
GEPDGMEL_01635 2.37e-249 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GEPDGMEL_01636 2.87e-22 - - - K - - - Transcriptional regulator, LacI family
GEPDGMEL_01637 3.5e-112 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
GEPDGMEL_01638 1.32e-114 - - - L - - - Integrase
GEPDGMEL_01639 6.6e-17 XK27_09155 - - K - - - Transcriptional
GEPDGMEL_01640 7.61e-217 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
GEPDGMEL_01641 0.0 gadC - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
GEPDGMEL_01642 1.2e-138 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GEPDGMEL_01643 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GEPDGMEL_01644 3.52e-274 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
GEPDGMEL_01645 5.83e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GEPDGMEL_01646 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GEPDGMEL_01647 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
GEPDGMEL_01648 6.92e-236 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
GEPDGMEL_01649 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
GEPDGMEL_01650 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GEPDGMEL_01651 1.05e-293 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
GEPDGMEL_01652 1.29e-313 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
GEPDGMEL_01653 2.08e-157 radC - - L ko:K03630 - ko00000 DNA repair protein
GEPDGMEL_01654 8.33e-230 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
GEPDGMEL_01655 1.1e-194 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
GEPDGMEL_01656 1.69e-120 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
GEPDGMEL_01657 3.13e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
GEPDGMEL_01658 1.02e-151 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GEPDGMEL_01659 8.15e-205 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
GEPDGMEL_01660 2.89e-292 ymfF - - S - - - Peptidase M16 inactive domain protein
GEPDGMEL_01661 4.81e-316 ymfH - - S - - - Peptidase M16
GEPDGMEL_01662 1.96e-194 - - - S - - - Helix-turn-helix domain
GEPDGMEL_01663 1.16e-133 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GEPDGMEL_01664 4.8e-291 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
GEPDGMEL_01665 7.67e-252 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GEPDGMEL_01666 9.31e-276 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
GEPDGMEL_01667 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GEPDGMEL_01668 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GEPDGMEL_01669 7.5e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GEPDGMEL_01670 2.86e-244 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GEPDGMEL_01671 4.43e-251 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GEPDGMEL_01672 6.13e-61 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
GEPDGMEL_01673 8.04e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
GEPDGMEL_01674 3.04e-313 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GEPDGMEL_01675 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GEPDGMEL_01676 8.03e-58 yrzL - - S - - - Belongs to the UPF0297 family
GEPDGMEL_01677 3.62e-100 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GEPDGMEL_01678 3.75e-63 yrzB - - S - - - Belongs to the UPF0473 family
GEPDGMEL_01679 8.35e-121 cvpA - - S - - - Colicin V production protein
GEPDGMEL_01680 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GEPDGMEL_01681 2.86e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
GEPDGMEL_01682 2.89e-124 yslB - - S - - - Protein of unknown function (DUF2507)
GEPDGMEL_01683 7.71e-186 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
GEPDGMEL_01684 3.47e-135 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GEPDGMEL_01685 3.71e-122 - - - S ko:K07095 - ko00000 Phosphoesterase
GEPDGMEL_01686 3.62e-100 ykuL - - S - - - (CBS) domain
GEPDGMEL_01687 1.99e-198 - - - S - - - haloacid dehalogenase-like hydrolase
GEPDGMEL_01688 2.65e-189 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
GEPDGMEL_01689 1.54e-71 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GEPDGMEL_01690 1.84e-75 - - - - - - - -
GEPDGMEL_01691 2.18e-269 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
GEPDGMEL_01692 2.41e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
GEPDGMEL_01693 1.15e-178 - - - - - - - -
GEPDGMEL_01694 7.07e-168 yebC - - K - - - Transcriptional regulatory protein
GEPDGMEL_01695 4.87e-234 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
GEPDGMEL_01696 3.26e-78 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
GEPDGMEL_01697 5.56e-139 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
GEPDGMEL_01698 1.27e-61 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
GEPDGMEL_01699 1.01e-100 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
GEPDGMEL_01700 4.99e-58 - - - - - - - -
GEPDGMEL_01701 8.95e-90 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
GEPDGMEL_01702 9.84e-184 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
GEPDGMEL_01703 5.54e-286 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GEPDGMEL_01704 9.97e-152 - - - S - - - Calcineurin-like phosphoesterase
GEPDGMEL_01705 3.03e-129 yutD - - S - - - Protein of unknown function (DUF1027)
GEPDGMEL_01706 2.91e-180 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GEPDGMEL_01707 1.61e-144 - - - S - - - Protein of unknown function (DUF1461)
GEPDGMEL_01708 1.51e-148 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
GEPDGMEL_01709 5.98e-157 - - - S - - - Domain of unknown function (DUF4811)
GEPDGMEL_01710 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
GEPDGMEL_01711 3.21e-99 - - - K - - - MerR HTH family regulatory protein
GEPDGMEL_01712 9.52e-74 - - - - - - - -
GEPDGMEL_01715 1.04e-30 - - - L - - - Replication initiation factor
GEPDGMEL_01717 1.92e-32 - - - S - - - Acyltransferase family
GEPDGMEL_01719 1.38e-117 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
GEPDGMEL_01720 1.75e-29 - - - - - - - -
GEPDGMEL_01721 3.61e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GEPDGMEL_01722 1.4e-147 - - - S - - - Protein of unknown function (DUF421)
GEPDGMEL_01723 3.21e-94 - - - S - - - Protein of unknown function (DUF3290)
GEPDGMEL_01724 7.03e-220 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GEPDGMEL_01725 4.95e-21 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GEPDGMEL_01726 2.14e-134 - - - L - - - Transposase and inactivated derivatives IS30 family
GEPDGMEL_01727 3.16e-22 - - - - - - - -
GEPDGMEL_01728 4e-208 - - - I - - - alpha/beta hydrolase fold
GEPDGMEL_01729 1.51e-148 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
GEPDGMEL_01730 6.28e-157 - - - L - - - Helix-turn-helix domain
GEPDGMEL_01732 4.77e-65 yrvD - - S - - - Pfam:DUF1049
GEPDGMEL_01733 1.54e-189 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
GEPDGMEL_01734 4.78e-91 - - - K - - - Transcriptional regulator, HxlR family
GEPDGMEL_01735 6.07e-165 - - - - - - - -
GEPDGMEL_01736 3.12e-23 - - - K - - - DNA-templated transcription, initiation
GEPDGMEL_01737 3.55e-133 int2 - - L - - - Belongs to the 'phage' integrase family
GEPDGMEL_01745 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GEPDGMEL_01746 7.14e-276 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
GEPDGMEL_01747 3.65e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GEPDGMEL_01748 2.49e-141 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GEPDGMEL_01749 5.46e-195 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GEPDGMEL_01750 1.97e-173 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GEPDGMEL_01751 4.83e-108 - - - T - - - Belongs to the universal stress protein A family
GEPDGMEL_01752 2.34e-142 - - - S - - - VIT family
GEPDGMEL_01753 7.33e-152 - - - S - - - membrane
GEPDGMEL_01754 4.92e-213 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
GEPDGMEL_01755 1.15e-161 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
GEPDGMEL_01756 2.17e-43 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
GEPDGMEL_01757 5.6e-171 - - - S - - - Putative threonine/serine exporter
GEPDGMEL_01758 3.68e-107 - - - S - - - Threonine/Serine exporter, ThrE
GEPDGMEL_01759 2.79e-153 - - - I - - - phosphatase
GEPDGMEL_01761 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
GEPDGMEL_01762 7.78e-150 dgk2 - - F - - - deoxynucleoside kinase
GEPDGMEL_01768 2.3e-229 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
GEPDGMEL_01769 1.8e-249 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
GEPDGMEL_01770 2.81e-101 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
GEPDGMEL_01771 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GEPDGMEL_01772 2.09e-143 - - - K - - - Bacterial regulatory proteins, tetR family
GEPDGMEL_01773 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GEPDGMEL_01774 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GEPDGMEL_01775 3.69e-260 - - - - - - - -
GEPDGMEL_01776 1.97e-153 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type II secretory pathway prepilin signal peptidase PulO and related peptidases
GEPDGMEL_01777 2.51e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GEPDGMEL_01778 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GEPDGMEL_01779 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GEPDGMEL_01780 5.98e-208 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GEPDGMEL_01781 1.07e-40 - - - L - - - Transposase
GEPDGMEL_01782 1.28e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
GEPDGMEL_01783 5.45e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GEPDGMEL_01784 6.64e-139 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
GEPDGMEL_01785 3.61e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GEPDGMEL_01786 1.64e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GEPDGMEL_01787 5.72e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GEPDGMEL_01788 4.36e-70 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GEPDGMEL_01789 9.81e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GEPDGMEL_01790 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GEPDGMEL_01791 5.49e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
GEPDGMEL_01792 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GEPDGMEL_01793 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GEPDGMEL_01794 5.22e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GEPDGMEL_01795 7.42e-125 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GEPDGMEL_01796 4.97e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GEPDGMEL_01797 1.54e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GEPDGMEL_01798 2.6e-124 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GEPDGMEL_01799 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GEPDGMEL_01800 5.95e-112 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GEPDGMEL_01801 5.94e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
GEPDGMEL_01802 6.05e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
GEPDGMEL_01803 1.66e-305 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GEPDGMEL_01804 4.52e-161 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GEPDGMEL_01805 2.41e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GEPDGMEL_01806 5.79e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
GEPDGMEL_01807 5.37e-76 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GEPDGMEL_01808 1.62e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GEPDGMEL_01809 1.27e-219 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GEPDGMEL_01810 8.08e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
GEPDGMEL_01811 2.47e-186 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GEPDGMEL_01812 4.31e-198 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GEPDGMEL_01813 8.27e-181 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GEPDGMEL_01814 4.31e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GEPDGMEL_01815 9.25e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GEPDGMEL_01816 3.94e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
GEPDGMEL_01817 4.46e-180 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
GEPDGMEL_01818 3.07e-149 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
GEPDGMEL_01819 4.76e-131 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GEPDGMEL_01820 1.27e-269 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GEPDGMEL_01821 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
GEPDGMEL_01822 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GEPDGMEL_01823 1.11e-260 camS - - S - - - sex pheromone
GEPDGMEL_01824 1.36e-66 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GEPDGMEL_01825 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GEPDGMEL_01826 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GEPDGMEL_01827 1.64e-237 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
GEPDGMEL_01828 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GEPDGMEL_01829 9.89e-315 - - - E ko:K03294 - ko00000 amino acid
GEPDGMEL_01830 3.89e-156 - - - L ko:K07497 - ko00000 hmm pf00665
GEPDGMEL_01831 6.57e-163 - - - L - - - Helix-turn-helix domain
GEPDGMEL_01832 0.0 - - - L - - - PFAM transposase, IS4 family protein
GEPDGMEL_01833 0.0 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
GEPDGMEL_01834 0.0 - - - S - - - Uncharacterised protein family (UPF0236)
GEPDGMEL_01835 1.89e-74 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GEPDGMEL_01836 2.93e-101 - - - L - - - Integrase core domain
GEPDGMEL_01837 2.11e-78 - - - O - - - Bacterial dnaA protein
GEPDGMEL_01838 3.83e-221 - - - L - - - Integrase core domain
GEPDGMEL_01840 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GEPDGMEL_01841 1.18e-221 - - - - - - - -
GEPDGMEL_01843 4.68e-90 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GEPDGMEL_01844 3.04e-122 - - - K - - - acetyltransferase
GEPDGMEL_01845 6.13e-216 - - - - - - - -
GEPDGMEL_01847 1.06e-276 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
GEPDGMEL_01848 3.32e-124 - - - S - - - AmiS/UreI family transporter
GEPDGMEL_01849 8.76e-63 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Urease, gamma subunit
GEPDGMEL_01850 6.94e-92 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Urease beta subunit
GEPDGMEL_01851 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Amidohydrolase family
GEPDGMEL_01852 3.08e-102 ureE - - O ko:K03187 - ko00000 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GEPDGMEL_01853 1.45e-170 ureF - - O ko:K03188 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
GEPDGMEL_01854 1.4e-145 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GEPDGMEL_01855 4.23e-212 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
GEPDGMEL_01856 1.35e-237 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
GEPDGMEL_01857 2.86e-184 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
GEPDGMEL_01858 6.63e-174 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GEPDGMEL_01859 4.65e-167 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
GEPDGMEL_01860 5.48e-202 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
GEPDGMEL_01861 9.65e-196 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
GEPDGMEL_01862 2.58e-197 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
GEPDGMEL_01863 4.47e-177 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GEPDGMEL_01864 6.82e-159 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
GEPDGMEL_01865 8.84e-186 - - - - - - - -
GEPDGMEL_01867 1.8e-96 - - - M - - - Glycosyl transferase
GEPDGMEL_01868 2.58e-179 ydaM - - M - - - Glycosyl transferase family group 2
GEPDGMEL_01869 2.62e-185 - - - G - - - Glycosyl hydrolases family 8
GEPDGMEL_01870 2.57e-80 - - - G - - - Glycosyl hydrolases family 8
GEPDGMEL_01871 3.28e-180 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
GEPDGMEL_01872 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
GEPDGMEL_01873 1.31e-302 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
GEPDGMEL_01874 2.8e-152 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
GEPDGMEL_01875 7.87e-113 - - - Q - - - Methyltransferase
GEPDGMEL_01876 2.3e-294 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
GEPDGMEL_01877 3.28e-229 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
GEPDGMEL_01878 1.92e-209 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
GEPDGMEL_01879 6.25e-107 - - - S - - - NADPH-dependent FMN reductase
GEPDGMEL_01880 1.1e-218 - - - S - - - Conserved hypothetical protein 698
GEPDGMEL_01881 8.91e-141 - - - I - - - alpha/beta hydrolase fold
GEPDGMEL_01882 1.22e-160 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
GEPDGMEL_01883 1.27e-219 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
GEPDGMEL_01884 0.0 arcD - - S - - - C4-dicarboxylate anaerobic carrier
GEPDGMEL_01885 0.0 arcT - - E - - - Dipeptidase
GEPDGMEL_01886 2.2e-272 - - - EGP - - - Transporter, major facilitator family protein
GEPDGMEL_01887 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
GEPDGMEL_01888 1.87e-176 - - - V - - - Beta-lactamase enzyme family
GEPDGMEL_01889 3.34e-286 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GEPDGMEL_01890 6.26e-96 - - - - - - - -
GEPDGMEL_01891 0.0 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GEPDGMEL_01892 4.47e-256 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
GEPDGMEL_01893 2.4e-37 - - - - - - - -
GEPDGMEL_01896 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
GEPDGMEL_01897 3.7e-72 - - - - - - - -
GEPDGMEL_01898 4.29e-179 - - - L ko:K07497 - ko00000 hmm pf00665
GEPDGMEL_01900 2.98e-92 - - - L ko:K07497 - ko00000 hmm pf00665
GEPDGMEL_01902 2.32e-104 usp5 - - T - - - universal stress protein
GEPDGMEL_01903 5.66e-106 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
GEPDGMEL_01904 2.14e-296 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GEPDGMEL_01905 6.28e-134 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
GEPDGMEL_01906 6.6e-230 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
GEPDGMEL_01907 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
GEPDGMEL_01908 1.03e-287 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GEPDGMEL_01909 3.14e-226 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
GEPDGMEL_01910 2.22e-186 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
GEPDGMEL_01911 5.55e-121 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
GEPDGMEL_01912 3.49e-48 - - - - - - - -
GEPDGMEL_01913 1.76e-68 - - - - - - - -
GEPDGMEL_01914 1.45e-257 - - - - - - - -
GEPDGMEL_01915 3.2e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GEPDGMEL_01916 2.79e-175 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
GEPDGMEL_01917 4.88e-200 yvgN - - S - - - Aldo keto reductase
GEPDGMEL_01918 1.06e-161 XK27_10500 - - K - - - response regulator
GEPDGMEL_01919 1.45e-231 kinG - - T - - - Histidine kinase-like ATPases
GEPDGMEL_01920 1.75e-174 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GEPDGMEL_01921 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
GEPDGMEL_01922 1.24e-195 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
GEPDGMEL_01923 1.03e-210 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
GEPDGMEL_01924 1.28e-65 - - - K - - - helix_turn_helix, mercury resistance
GEPDGMEL_01925 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GEPDGMEL_01926 1.41e-250 - - - EGP - - - Major Facilitator
GEPDGMEL_01927 3.48e-112 ymdB - - S - - - Macro domain protein
GEPDGMEL_01928 1.75e-141 - - - K - - - Helix-turn-helix domain
GEPDGMEL_01929 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
GEPDGMEL_01930 1.21e-63 - - - - - - - -
GEPDGMEL_01931 6.86e-294 - - - S - - - Putative metallopeptidase domain
GEPDGMEL_01932 6.62e-258 - - - S - - - associated with various cellular activities
GEPDGMEL_01933 2.34e-154 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
GEPDGMEL_01934 8.5e-86 yeaO - - S - - - Protein of unknown function, DUF488
GEPDGMEL_01936 7.61e-148 yrkL - - S - - - Flavodoxin-like fold
GEPDGMEL_01937 3.32e-72 - - - - - - - -
GEPDGMEL_01939 5.48e-71 - 2.1.1.72 - D ko:K03427 - ko00000,ko01000,ko02048 peptidase
GEPDGMEL_01940 1.19e-73 - - - S - - - PD-(D/E)XK nuclease family transposase
GEPDGMEL_01941 2.04e-65 - - - - - - - -
GEPDGMEL_01945 1.69e-16 - - - K - - - Helix-turn-helix domain
GEPDGMEL_01947 3.99e-257 yngD - - S ko:K07097 - ko00000 DHHA1 domain
GEPDGMEL_01948 1.1e-294 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
GEPDGMEL_01949 1.24e-314 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
GEPDGMEL_01950 4.21e-137 - - - NU - - - mannosyl-glycoprotein
GEPDGMEL_01951 1.23e-178 - - - S - - - Putative ABC-transporter type IV
GEPDGMEL_01952 0.0 - - - S - - - ABC transporter, ATP-binding protein
GEPDGMEL_01953 1.11e-117 - - - K - - - Helix-turn-helix domain
GEPDGMEL_01954 3.85e-66 - - - - - - - -
GEPDGMEL_01955 2.58e-41 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
GEPDGMEL_01956 1.54e-128 - - - S - - - Protein of unknown function (DUF3278)
GEPDGMEL_01958 6.29e-170 - - - M - - - PFAM NLP P60 protein
GEPDGMEL_01959 3.69e-232 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
GEPDGMEL_01960 1.18e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GEPDGMEL_01961 3.96e-177 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GEPDGMEL_01962 5.77e-121 - - - P - - - Cadmium resistance transporter
GEPDGMEL_01963 1.09e-72 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
GEPDGMEL_01964 1.12e-92 - - - L - - - PFAM Integrase catalytic region
GEPDGMEL_01968 1.23e-64 - - - L - - - Bacterial dnaA protein
GEPDGMEL_01974 1.09e-101 tnpR1 - - L - - - Resolvase, N terminal domain
GEPDGMEL_01975 2.66e-178 - - - - - - - -
GEPDGMEL_01976 0.0 - - - - - - - -
GEPDGMEL_01978 1.11e-45 - - - S - - - Domain of unknown function (DUF3173)
GEPDGMEL_01979 1.74e-291 - - - L - - - Belongs to the 'phage' integrase family
GEPDGMEL_01980 3.34e-112 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GEPDGMEL_01981 0.0 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GEPDGMEL_01982 2.6e-215 cpsY - - K - - - Transcriptional regulator, LysR family
GEPDGMEL_01983 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GEPDGMEL_01984 7.19e-198 metF 1.5.1.20 - C ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
GEPDGMEL_01985 8.6e-72 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GEPDGMEL_01987 7.79e-281 - - - L - - - transposase IS116 IS110 IS902 family protein
GEPDGMEL_01988 1.69e-60 - - - L - - - Transposase
GEPDGMEL_01989 1.39e-62 - - - L - - - Transposase
GEPDGMEL_01990 1.34e-84 - - - L - - - Transposase
GEPDGMEL_01991 2.64e-43 - - - L - - - PFAM Integrase catalytic region
GEPDGMEL_01992 7.15e-198 - - - J - - - Methyltransferase
GEPDGMEL_01993 7.66e-103 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
GEPDGMEL_01994 6.69e-283 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
GEPDGMEL_01995 1.47e-130 ywlG - - S - - - Belongs to the UPF0340 family
GEPDGMEL_01996 1.27e-253 - - - EGP - - - Major Facilitator
GEPDGMEL_01997 8.58e-17 - - - M - - - Lysin motif
GEPDGMEL_01998 1.56e-136 - - - M - - - Lysin motif
GEPDGMEL_01999 1.34e-103 - - - - - - - -
GEPDGMEL_02000 2.18e-217 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
GEPDGMEL_02001 6.95e-122 - - - K - - - PFAM GCN5-related N-acetyltransferase
GEPDGMEL_02002 7.27e-266 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
GEPDGMEL_02003 3.7e-19 - - - - - - - -
GEPDGMEL_02004 4.44e-117 - - - S - - - Domain of unknown function (DUF4767)
GEPDGMEL_02005 5.17e-249 - 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
GEPDGMEL_02006 7.26e-146 - - - S - - - Membrane
GEPDGMEL_02007 3.53e-158 - - - O - - - Zinc-dependent metalloprotease
GEPDGMEL_02008 1.33e-114 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GEPDGMEL_02009 1.84e-203 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GEPDGMEL_02011 0.0 - - - M - - - Leucine-rich repeat (LRR) protein
GEPDGMEL_02012 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
GEPDGMEL_02013 5.58e-249 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
GEPDGMEL_02014 3.47e-233 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)