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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
DOALAIPI_00001	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
DOALAIPI_00002	1.03e-19	-	-	-	-	-	-	-	-
DOALAIPI_00003	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DOALAIPI_00004	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DOALAIPI_00005	1.5e-315	steT	-	-	E	ko:K03294	-	ko00000	amino acid
DOALAIPI_00006	3.28e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
DOALAIPI_00007	1.41e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
DOALAIPI_00008	1.37e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
DOALAIPI_00010	1.83e-21	-	-	-	-	-	-	-	-
DOALAIPI_00011	1.01e-308	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
DOALAIPI_00012	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DOALAIPI_00014	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DOALAIPI_00015	7.62e-290	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
DOALAIPI_00016	2.51e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DOALAIPI_00017	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DOALAIPI_00018	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
DOALAIPI_00019	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
DOALAIPI_00020	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
DOALAIPI_00021	1.34e-186	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
DOALAIPI_00022	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DOALAIPI_00023	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DOALAIPI_00024	2.26e-135	-	-	-	-	-	-	-	-
DOALAIPI_00025	7.51e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DOALAIPI_00026	1.38e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
DOALAIPI_00027	6.95e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
DOALAIPI_00028	6.2e-114	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DOALAIPI_00029	1.69e-97	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
DOALAIPI_00030	3.7e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
DOALAIPI_00031	3.36e-216	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
DOALAIPI_00032	1.52e-212	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DOALAIPI_00033	1.01e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
DOALAIPI_00034	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
DOALAIPI_00035	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DOALAIPI_00036	8.71e-164	ybbR	-	-	S	-	-	-	YbbR-like protein
DOALAIPI_00037	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DOALAIPI_00038	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DOALAIPI_00039	5.17e-70	-	-	-	-	-	-	-	-
DOALAIPI_00040	0.0	oatA	-	-	I	-	-	-	Acyltransferase
DOALAIPI_00041	2.14e-105	-	-	-	K	-	-	-	Transcriptional regulator
DOALAIPI_00042	9.84e-194	-	-	-	S	-	-	-	Cof-like hydrolase
DOALAIPI_00043	2.2e-110	lytE	-	-	M	-	-	-	Lysin motif
DOALAIPI_00045	4.48e-171	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
DOALAIPI_00046	0.0	yclK	-	-	T	-	-	-	Histidine kinase
DOALAIPI_00047	1.34e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
DOALAIPI_00048	4.93e-153	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
DOALAIPI_00049	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
DOALAIPI_00050	2.49e-39	-	-	-	-	-	-	-	-
DOALAIPI_00051	1.83e-277	xylR	-	-	GK	-	-	-	ROK family
DOALAIPI_00053	0.0	xylT	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
DOALAIPI_00054	8.96e-223	rhaS2	-	-	K	-	-	-	Transcriptional regulator, AraC family
DOALAIPI_00055	0.0	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
DOALAIPI_00056	0.0	-	-	-	G	-	-	-	Right handed beta helix region
DOALAIPI_00057	7.22e-28	pgdA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	polysaccharide deacetylase
DOALAIPI_00058	8.8e-17	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	polysaccharide deacetylase
DOALAIPI_00059	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
DOALAIPI_00060	0.0	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
DOALAIPI_00061	2.61e-199	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
DOALAIPI_00062	3.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DOALAIPI_00063	1.13e-220	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
DOALAIPI_00064	5.49e-207	-	-	-	EG	-	-	-	EamA-like transporter family
DOALAIPI_00065	1.72e-134	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
DOALAIPI_00066	1.6e-82	-	-	-	S	-	-	-	Cupredoxin-like domain
DOALAIPI_00067	2.2e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
DOALAIPI_00068	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
DOALAIPI_00069	4.47e-113	-	-	-	-	-	-	-	-
DOALAIPI_00071	1.28e-75	-	-	-	-	-	-	-	-
DOALAIPI_00072	2.19e-199	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
DOALAIPI_00073	1.7e-88	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
DOALAIPI_00075	9.21e-131	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DOALAIPI_00076	4.56e-56	-	-	-	-	-	-	-	-
DOALAIPI_00077	2.27e-09	-	-	-	S	-	-	-	Short C-terminal domain
DOALAIPI_00078	1.67e-47	-	-	-	S	-	-	-	IrrE N-terminal-like domain
DOALAIPI_00079	3.39e-22	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DOALAIPI_00085	2.2e-21	-	-	-	-	-	-	-	-
DOALAIPI_00088	2.08e-158	-	-	-	L	-	-	-	DnaD domain protein
DOALAIPI_00089	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DOALAIPI_00090	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
DOALAIPI_00091	1.83e-181	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
DOALAIPI_00092	2.09e-116	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DOALAIPI_00093	3.74e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
DOALAIPI_00094	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
DOALAIPI_00095	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DOALAIPI_00096	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DOALAIPI_00097	3.4e-280	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DOALAIPI_00098	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
DOALAIPI_00099	1.57e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DOALAIPI_00100	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOALAIPI_00101	1.3e-238	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DOALAIPI_00102	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DOALAIPI_00103	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
DOALAIPI_00104	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
DOALAIPI_00105	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
DOALAIPI_00106	6.67e-157	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
DOALAIPI_00107	3.69e-150	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
DOALAIPI_00108	4.2e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DOALAIPI_00109	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
DOALAIPI_00110	8.61e-168	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
DOALAIPI_00111	3.43e-315	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DOALAIPI_00112	7.08e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DOALAIPI_00113	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DOALAIPI_00114	5.78e-269	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DOALAIPI_00115	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DOALAIPI_00116	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
DOALAIPI_00117	9e-72	-	-	-	-	-	-	-	-
DOALAIPI_00118	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
DOALAIPI_00119	7.84e-101	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
DOALAIPI_00120	9.79e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
DOALAIPI_00121	2.49e-198	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
DOALAIPI_00122	2.83e-58	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DOALAIPI_00123	2.46e-306	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DOALAIPI_00124	5.39e-191	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DOALAIPI_00125	3.71e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DOALAIPI_00126	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
DOALAIPI_00127	9.67e-57	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
DOALAIPI_00128	6.86e-67	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
DOALAIPI_00129	4.13e-254	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
DOALAIPI_00130	7.14e-166	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DOALAIPI_00131	5.93e-60	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
DOALAIPI_00132	7.21e-72	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
DOALAIPI_00133	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
DOALAIPI_00134	5.7e-146	-	-	-	K	-	-	-	Transcriptional regulator
DOALAIPI_00137	9.16e-111	-	-	-	S	-	-	-	Protein conserved in bacteria
DOALAIPI_00138	6.65e-236	-	-	-	-	-	-	-	-
DOALAIPI_00139	4.87e-203	-	-	-	-	-	-	-	-
DOALAIPI_00140	2.56e-66	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
DOALAIPI_00141	5.71e-131	msrA	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DOALAIPI_00142	6.16e-200	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
DOALAIPI_00143	1.28e-18	-	-	-	-	-	-	-	-
DOALAIPI_00144	1.25e-284	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DOALAIPI_00145	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DOALAIPI_00146	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
DOALAIPI_00147	1.13e-223	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DOALAIPI_00148	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
DOALAIPI_00149	2.81e-88	yqhL	-	-	P	-	-	-	Rhodanese-like protein
DOALAIPI_00150	2.51e-235	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
DOALAIPI_00151	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
DOALAIPI_00152	2.39e-147	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
DOALAIPI_00153	1.55e-128	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DOALAIPI_00154	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
DOALAIPI_00155	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
DOALAIPI_00156	0.0	-	-	-	S	-	-	-	membrane
DOALAIPI_00157	1.89e-91	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
DOALAIPI_00158	6.08e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DOALAIPI_00159	4.85e-151	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
DOALAIPI_00160	1.4e-147	-	-	-	M	-	-	-	PFAM NLP P60 protein
DOALAIPI_00161	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DOALAIPI_00162	3.66e-252	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DOALAIPI_00163	5.79e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
DOALAIPI_00164	3.75e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
DOALAIPI_00165	1.1e-185	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DOALAIPI_00166	9.98e-58	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
DOALAIPI_00167	1.16e-216	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DOALAIPI_00168	1.85e-90	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
DOALAIPI_00169	5.62e-294	-	-	-	V	-	-	-	MatE
DOALAIPI_00170	0.0	potE	-	-	E	-	-	-	Amino Acid
DOALAIPI_00171	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DOALAIPI_00172	9.72e-156	csrR	-	-	K	-	-	-	response regulator
DOALAIPI_00173	1.36e-72	-	-	-	-	-	-	-	-
DOALAIPI_00174	5.74e-264	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
DOALAIPI_00176	1.34e-297	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
DOALAIPI_00177	4.39e-244	mocA	-	-	S	-	-	-	Oxidoreductase
DOALAIPI_00178	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
DOALAIPI_00179	6.95e-134	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
DOALAIPI_00180	1.31e-213	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
DOALAIPI_00181	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
DOALAIPI_00182	5.72e-243	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
DOALAIPI_00183	2.61e-95	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
DOALAIPI_00184	2.64e-152	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
DOALAIPI_00185	1.7e-26	-	-	-	-	-	-	-	-
DOALAIPI_00186	1.61e-97	-	-	-	K	-	-	-	LytTr DNA-binding domain
DOALAIPI_00187	8.85e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
DOALAIPI_00188	5.19e-186	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
DOALAIPI_00189	8.76e-27	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
DOALAIPI_00190	1.93e-36	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
DOALAIPI_00191	8.42e-156	pnb	-	-	C	-	-	-	nitroreductase
DOALAIPI_00192	4.61e-114	-	-	-	-	-	-	-	-
DOALAIPI_00193	8.72e-314	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
DOALAIPI_00194	7.09e-51	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
DOALAIPI_00195	3.01e-107	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
DOALAIPI_00197	6.57e-63	-	-	-	-	-	-	-	-
DOALAIPI_00198	4.16e-198	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DOALAIPI_00199	1.17e-188	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
DOALAIPI_00200	8.81e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
DOALAIPI_00201	1.39e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
DOALAIPI_00203	3.65e-223	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
DOALAIPI_00206	0.0	-	-	-	L	-	-	-	helicase activity
DOALAIPI_00207	3.95e-277	-	-	-	K	-	-	-	DNA binding
DOALAIPI_00208	0.0	res	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
DOALAIPI_00209	5.86e-305	mod	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
DOALAIPI_00213	2.11e-30	-	-	-	E	-	-	-	Pfam:DUF955
DOALAIPI_00214	5.69e-16	-	-	-	S	-	-	-	Protein conserved in bacteria
DOALAIPI_00215	5.44e-31	-	-	-	-	-	-	-	-
DOALAIPI_00216	6.91e-25	-	-	-	-	-	-	-	-
DOALAIPI_00217	3.22e-39	-	-	-	S	-	-	-	Domain of unknown function (DUF4417)
DOALAIPI_00218	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DOALAIPI_00219	1.15e-237	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
DOALAIPI_00220	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DOALAIPI_00221	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DOALAIPI_00222	9.59e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DOALAIPI_00223	5.26e-259	camS	-	-	S	-	-	-	sex pheromone
DOALAIPI_00224	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DOALAIPI_00225	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
DOALAIPI_00226	2.19e-270	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DOALAIPI_00227	1.94e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DOALAIPI_00228	5.09e-148	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
DOALAIPI_00229	2.58e-179	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
DOALAIPI_00232	1.33e-106	-	-	-	S	-	-	-	GIY-YIG catalytic domain
DOALAIPI_00233	1.21e-60	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
DOALAIPI_00234	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
DOALAIPI_00235	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DOALAIPI_00236	5.87e-180	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DOALAIPI_00237	8.27e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DOALAIPI_00238	1.83e-199	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DOALAIPI_00239	4.1e-185	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DOALAIPI_00240	6.64e-82	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
DOALAIPI_00241	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DOALAIPI_00242	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DOALAIPI_00243	5.37e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DOALAIPI_00244	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
DOALAIPI_00245	2.41e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DOALAIPI_00246	4.52e-161	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DOALAIPI_00247	6.77e-305	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DOALAIPI_00248	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
DOALAIPI_00249	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
DOALAIPI_00250	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DOALAIPI_00251	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DOALAIPI_00252	2.6e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DOALAIPI_00253	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DOALAIPI_00254	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DOALAIPI_00255	3.02e-64	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DOALAIPI_00256	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DOALAIPI_00257	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DOALAIPI_00258	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
DOALAIPI_00259	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DOALAIPI_00260	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DOALAIPI_00261	4.36e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DOALAIPI_00262	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DOALAIPI_00263	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DOALAIPI_00264	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DOALAIPI_00265	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
DOALAIPI_00266	9.05e-152	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DOALAIPI_00267	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
DOALAIPI_00268	4.03e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
DOALAIPI_00269	2.27e-75	-	-	-	S	-	-	-	Small secreted protein
DOALAIPI_00270	2.09e-214	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
DOALAIPI_00271	1.83e-232	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
DOALAIPI_00272	1.99e-252	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
DOALAIPI_00273	7.52e-51	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
DOALAIPI_00274	2.34e-26	-	-	-	A	ko:K12092	ko05120,map05120	ko00000,ko00001,ko00002,ko02044	chlorophyll binding
DOALAIPI_00275	2.21e-100	-	-	-	A	ko:K12092	ko05120,map05120	ko00000,ko00001,ko00002,ko02044	chlorophyll binding
DOALAIPI_00276	6.51e-51	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
DOALAIPI_00277	1.03e-154	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DOALAIPI_00278	1.5e-275	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
DOALAIPI_00279	1.34e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DOALAIPI_00280	1.49e-102	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
DOALAIPI_00282	3.96e-178	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DOALAIPI_00283	0.0	yhaN	-	-	L	-	-	-	AAA domain
DOALAIPI_00284	2.57e-273	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
DOALAIPI_00285	5.69e-63	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
DOALAIPI_00286	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
DOALAIPI_00287	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
DOALAIPI_00288	2.51e-193	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
DOALAIPI_00289	2.24e-212	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
DOALAIPI_00291	4.26e-54	-	-	-	-	-	-	-	-
DOALAIPI_00292	4.61e-61	-	-	-	-	-	-	-	-
DOALAIPI_00293	2.69e-276	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
DOALAIPI_00294	2.85e-134	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
DOALAIPI_00295	5.27e-281	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
DOALAIPI_00296	4.58e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
DOALAIPI_00297	7.55e-120	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
DOALAIPI_00298	1.43e-73	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DOALAIPI_00299	3e-89	-	-	-	-	-	-	-	-
DOALAIPI_00301	9.17e-59	-	-	-	-	-	-	-	-
DOALAIPI_00302	1.49e-153	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DOALAIPI_00303	1.52e-43	-	-	-	-	-	-	-	-
DOALAIPI_00304	8.09e-208	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DOALAIPI_00305	1.03e-237	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
DOALAIPI_00306	5.12e-145	-	-	-	-	-	-	-	-
DOALAIPI_00307	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
DOALAIPI_00308	7.46e-223	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DOALAIPI_00309	1.08e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
DOALAIPI_00310	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
DOALAIPI_00311	3.79e-191	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DOALAIPI_00312	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
DOALAIPI_00313	1.2e-54	-	-	-	-	-	-	-	-
DOALAIPI_00314	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
DOALAIPI_00315	1.57e-279	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DOALAIPI_00316	1.62e-123	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
DOALAIPI_00317	0.0	-	-	-	EGP	-	-	-	Major Facilitator
DOALAIPI_00318	3.59e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
DOALAIPI_00319	1.11e-299	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
DOALAIPI_00320	1.37e-133	-	-	-	V	-	-	-	VanZ like family
DOALAIPI_00321	7.03e-33	-	-	-	-	-	-	-	-
DOALAIPI_00322	7.14e-111	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
DOALAIPI_00323	6.26e-101	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
DOALAIPI_00324	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
DOALAIPI_00325	2.68e-100	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
DOALAIPI_00326	7.67e-191	yeaE	-	-	S	-	-	-	Aldo keto
DOALAIPI_00327	1.54e-307	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
DOALAIPI_00328	1.93e-288	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
DOALAIPI_00329	1.99e-190	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
DOALAIPI_00330	3.37e-139	-	-	-	M	-	-	-	LysM domain protein
DOALAIPI_00331	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
DOALAIPI_00332	2.73e-148	-	-	-	M	-	-	-	LysM domain protein
DOALAIPI_00333	1.52e-141	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
DOALAIPI_00334	1.37e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DOALAIPI_00335	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
DOALAIPI_00336	4.46e-310	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
DOALAIPI_00337	3.01e-126	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DOALAIPI_00338	0.000556	-	-	-	E	-	-	-	Zn peptidase
DOALAIPI_00341	2.49e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
DOALAIPI_00342	9.31e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DOALAIPI_00343	5.99e-74	ftsL	-	-	D	-	-	-	Cell division protein FtsL
DOALAIPI_00344	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
DOALAIPI_00345	3.83e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DOALAIPI_00346	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DOALAIPI_00347	1.7e-259	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DOALAIPI_00348	9.97e-185	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DOALAIPI_00349	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DOALAIPI_00350	6.52e-289	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DOALAIPI_00351	1.11e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DOALAIPI_00352	3.2e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
DOALAIPI_00353	3.71e-190	ylmH	-	-	S	-	-	-	S4 domain protein
DOALAIPI_00354	1.51e-108	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
DOALAIPI_00355	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DOALAIPI_00356	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
DOALAIPI_00357	2.48e-129	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
DOALAIPI_00358	1.54e-33	-	-	-	-	-	-	-	-
DOALAIPI_00359	3.97e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DOALAIPI_00360	1.56e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
DOALAIPI_00361	2.27e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
DOALAIPI_00362	1.25e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DOALAIPI_00363	1.15e-158	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
DOALAIPI_00364	1.43e-152	-	-	-	S	-	-	-	repeat protein
DOALAIPI_00365	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DOALAIPI_00366	1.48e-223	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DOALAIPI_00367	1.78e-240	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DOALAIPI_00368	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
DOALAIPI_00369	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DOALAIPI_00370	2.66e-111	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
DOALAIPI_00371	5.25e-280	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
DOALAIPI_00372	1.96e-224	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DOALAIPI_00373	2.69e-182	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DOALAIPI_00374	1.69e-278	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DOALAIPI_00375	1.49e-253	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DOALAIPI_00376	2.52e-263	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
DOALAIPI_00377	3.71e-76	-	-	-	-	-	-	-	-
DOALAIPI_00379	2.78e-227	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
DOALAIPI_00380	7.27e-38	-	-	-	-	-	-	-	-
DOALAIPI_00381	1.45e-230	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
DOALAIPI_00382	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
DOALAIPI_00383	1.33e-105	-	-	-	-	-	-	-	-
DOALAIPI_00384	6.83e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DOALAIPI_00385	4.05e-266	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
DOALAIPI_00386	3.28e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
DOALAIPI_00387	2.48e-310	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DOALAIPI_00388	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
DOALAIPI_00389	7.04e-63	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
DOALAIPI_00390	9.67e-175	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
DOALAIPI_00391	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
DOALAIPI_00392	7.88e-286	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
DOALAIPI_00393	2.5e-57	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
DOALAIPI_00394	3.23e-127	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
DOALAIPI_00395	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DOALAIPI_00396	1.82e-253	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
DOALAIPI_00397	8.97e-136	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
DOALAIPI_00398	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
DOALAIPI_00399	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
DOALAIPI_00400	1.32e-192	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
DOALAIPI_00401	2.38e-68	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
DOALAIPI_00402	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DOALAIPI_00403	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DOALAIPI_00404	5.67e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DOALAIPI_00406	5.06e-285	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
DOALAIPI_00407	1.69e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
DOALAIPI_00408	6.78e-218	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
DOALAIPI_00409	5.97e-208	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
DOALAIPI_00410	1.09e-163	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
DOALAIPI_00411	6.46e-201	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
DOALAIPI_00412	2.79e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
DOALAIPI_00413	2.79e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
DOALAIPI_00414	5.8e-43	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
DOALAIPI_00415	1.75e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DOALAIPI_00416	8.58e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
DOALAIPI_00417	2.29e-152	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DOALAIPI_00418	5.41e-297	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DOALAIPI_00419	1.65e-302	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
DOALAIPI_00420	1.89e-166	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
DOALAIPI_00421	6.53e-220	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
DOALAIPI_00422	4.21e-265	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DOALAIPI_00423	9.76e-161	vanR	-	-	K	-	-	-	response regulator
DOALAIPI_00424	1.59e-265	hpk31	-	-	T	-	-	-	Histidine kinase
DOALAIPI_00425	3.97e-185	-	-	-	E	-	-	-	AzlC protein
DOALAIPI_00426	9.94e-71	-	-	-	S	-	-	-	branched-chain amino acid
DOALAIPI_00427	3.07e-40	-	-	-	K	-	-	-	LysR substrate binding domain
DOALAIPI_00428	3.82e-106	-	-	-	K	-	-	-	LysR substrate binding domain
DOALAIPI_00429	1.48e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
DOALAIPI_00430	2.38e-310	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DOALAIPI_00431	1.95e-220	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DOALAIPI_00432	1.96e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DOALAIPI_00433	2.61e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DOALAIPI_00434	1.51e-147	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
DOALAIPI_00435	2.72e-290	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
DOALAIPI_00436	6.76e-227	ydbI	-	-	K	-	-	-	AI-2E family transporter
DOALAIPI_00437	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
DOALAIPI_00438	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
DOALAIPI_00439	7.09e-163	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
DOALAIPI_00440	5.18e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DOALAIPI_00441	2.48e-275	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DOALAIPI_00442	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DOALAIPI_00443	1.82e-170	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
DOALAIPI_00444	1.84e-49	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DOALAIPI_00445	1.9e-161	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DOALAIPI_00446	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DOALAIPI_00447	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DOALAIPI_00448	1.65e-242	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
DOALAIPI_00449	1.13e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DOALAIPI_00450	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
DOALAIPI_00451	1.31e-306	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
DOALAIPI_00452	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DOALAIPI_00453	1.49e-231	-	-	-	-	-	-	-	-
DOALAIPI_00454	6.99e-305	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DOALAIPI_00455	1.83e-313	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
DOALAIPI_00456	8.42e-26	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
DOALAIPI_00457	1.97e-110	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
DOALAIPI_00458	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
DOALAIPI_00459	2.58e-193	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
DOALAIPI_00460	1.69e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
DOALAIPI_00461	3.13e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
DOALAIPI_00462	3.99e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DOALAIPI_00463	8.15e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
DOALAIPI_00464	6.81e-291	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
DOALAIPI_00465	1.83e-315	ymfH	-	-	S	-	-	-	Peptidase M16
DOALAIPI_00466	1.18e-195	-	-	-	S	-	-	-	Helix-turn-helix domain
DOALAIPI_00467	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DOALAIPI_00468	1.13e-289	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
DOALAIPI_00469	7.67e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DOALAIPI_00470	1.54e-274	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
DOALAIPI_00471	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DOALAIPI_00472	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DOALAIPI_00473	7.5e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DOALAIPI_00474	8.19e-244	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DOALAIPI_00475	1.8e-250	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DOALAIPI_00476	6.13e-61	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
DOALAIPI_00477	1.76e-233	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
DOALAIPI_00478	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DOALAIPI_00479	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DOALAIPI_00480	6.61e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
DOALAIPI_00481	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DOALAIPI_00482	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
DOALAIPI_00483	8.35e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
DOALAIPI_00484	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DOALAIPI_00485	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
DOALAIPI_00486	2.89e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
DOALAIPI_00487	1.89e-186	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
DOALAIPI_00488	3.47e-135	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DOALAIPI_00489	6.16e-121	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
DOALAIPI_00490	3.62e-100	ykuL	-	-	S	-	-	-	(CBS) domain
DOALAIPI_00491	2.23e-190	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
DOALAIPI_00492	1.86e-189	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
DOALAIPI_00493	1.04e-69	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DOALAIPI_00494	3.38e-71	-	-	-	-	-	-	-	-
DOALAIPI_00495	2.18e-269	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
DOALAIPI_00496	1.39e-234	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
DOALAIPI_00497	2.32e-178	-	-	-	-	-	-	-	-
DOALAIPI_00498	7.07e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
DOALAIPI_00499	9.82e-234	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
DOALAIPI_00500	2.49e-232	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
DOALAIPI_00501	1.27e-61	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
DOALAIPI_00502	1.01e-100	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
DOALAIPI_00503	2.78e-55	-	-	-	-	-	-	-	-
DOALAIPI_00504	7.66e-91	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
DOALAIPI_00505	1.46e-185	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
DOALAIPI_00506	5.54e-286	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DOALAIPI_00507	1.93e-149	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
DOALAIPI_00508	5.03e-128	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
DOALAIPI_00509	2.05e-180	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DOALAIPI_00510	3.4e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
DOALAIPI_00511	1.06e-148	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
DOALAIPI_00512	6.82e-119	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
DOALAIPI_00513	2.55e-247	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DOALAIPI_00514	7.95e-272	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
DOALAIPI_00515	5.49e-214	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
DOALAIPI_00516	2.45e-218	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
DOALAIPI_00517	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
DOALAIPI_00518	2.23e-113	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
DOALAIPI_00519	6.82e-159	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
DOALAIPI_00520	7.75e-205	-	-	-	EG	-	-	-	EamA-like transporter family
DOALAIPI_00521	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
DOALAIPI_00522	8.19e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DOALAIPI_00523	5.84e-131	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
DOALAIPI_00524	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DOALAIPI_00525	4.13e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
DOALAIPI_00526	1.46e-283	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
DOALAIPI_00527	3.65e-90	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
DOALAIPI_00528	2.58e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
DOALAIPI_00529	8.16e-93	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DOALAIPI_00530	5.85e-224	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DOALAIPI_00531	2.62e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
DOALAIPI_00532	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
DOALAIPI_00533	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
DOALAIPI_00534	2.95e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
DOALAIPI_00535	9e-124	-	-	-	-	-	-	-	-
DOALAIPI_00536	2.14e-154	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
DOALAIPI_00537	8.1e-200	gspA	-	-	M	-	-	-	family 8
DOALAIPI_00538	3.46e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
DOALAIPI_00539	4.52e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DOALAIPI_00540	2.97e-54	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
DOALAIPI_00541	9.51e-116	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
DOALAIPI_00542	4.92e-68	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
DOALAIPI_00543	6.59e-23	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
DOALAIPI_00544	2.32e-48	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
DOALAIPI_00545	1.59e-213	yvgN	-	-	C	-	-	-	Aldo keto reductase
DOALAIPI_00546	5.68e-83	-	-	-	K	-	-	-	Transcriptional regulator
DOALAIPI_00547	9.73e-100	-	-	-	S	-	-	-	Cupin domain
DOALAIPI_00548	1.09e-57	-	-	-	S	-	-	-	UPF0756 membrane protein
DOALAIPI_00549	2.49e-310	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
DOALAIPI_00550	2.39e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
DOALAIPI_00551	6.7e-315	yhdP	-	-	S	-	-	-	Transporter associated domain
DOALAIPI_00552	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
DOALAIPI_00553	5.87e-169	-	-	-	S	-	-	-	DUF218 domain
DOALAIPI_00554	3.39e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DOALAIPI_00555	1.25e-76	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DOALAIPI_00556	5.16e-72	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DOALAIPI_00557	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
DOALAIPI_00558	5.85e-158	-	-	-	S	-	-	-	SNARE associated Golgi protein
DOALAIPI_00559	1.09e-292	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
DOALAIPI_00560	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DOALAIPI_00562	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
DOALAIPI_00563	1.99e-201	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
DOALAIPI_00564	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOALAIPI_00565	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
DOALAIPI_00566	1.06e-235	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
DOALAIPI_00567	6.28e-218	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
DOALAIPI_00568	5.64e-228	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
DOALAIPI_00569	3.6e-160	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
DOALAIPI_00570	3.69e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
DOALAIPI_00571	2.9e-169	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
DOALAIPI_00572	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
DOALAIPI_00573	1.8e-190	-	-	-	O	-	-	-	Band 7 protein
DOALAIPI_00574	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
DOALAIPI_00575	2.62e-199	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
DOALAIPI_00576	1.01e-51	-	-	-	S	-	-	-	Cytochrome B5
DOALAIPI_00577	1.66e-60	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
DOALAIPI_00578	1.29e-203	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
DOALAIPI_00579	3.38e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
DOALAIPI_00580	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
DOALAIPI_00581	3.71e-105	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
DOALAIPI_00582	9.08e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DOALAIPI_00583	1.85e-302	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
DOALAIPI_00584	5.43e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
DOALAIPI_00585	2.32e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
DOALAIPI_00586	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
DOALAIPI_00587	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
DOALAIPI_00588	5.49e-198	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DOALAIPI_00589	4.73e-85	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
DOALAIPI_00590	8.27e-141	-	-	-	K	ko:K03091	-	ko00000,ko03021	RNA polymerase sigma factor, sigma-70 family
DOALAIPI_00591	1.05e-272	-	-	-	G	-	-	-	Transporter, major facilitator family protein
DOALAIPI_00592	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
DOALAIPI_00593	1.49e-145	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
DOALAIPI_00594	2.72e-102	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
DOALAIPI_00595	6.2e-285	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
DOALAIPI_00596	1.34e-130	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
DOALAIPI_00597	1.26e-245	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DOALAIPI_00598	1.05e-227	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
DOALAIPI_00600	0.0	-	-	-	L	-	-	-	PLD-like domain
DOALAIPI_00601	1.85e-22	-	-	-	-	-	-	-	-
DOALAIPI_00602	1.14e-121	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
DOALAIPI_00603	1.3e-211	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
DOALAIPI_00604	1.39e-85	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	PFAM restriction modification system DNA specificity domain
DOALAIPI_00605	4.83e-227	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DOALAIPI_00606	3.94e-74	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
DOALAIPI_00607	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
DOALAIPI_00608	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
DOALAIPI_00609	2.48e-21	-	-	-	-	-	-	-	-
DOALAIPI_00610	2.35e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
DOALAIPI_00611	5.59e-120	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
DOALAIPI_00612	1.79e-287	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DOALAIPI_00613	4.16e-177	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
DOALAIPI_00614	9.25e-66	udp	2.4.2.3	-	F	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphorylase superfamily
DOALAIPI_00615	1.91e-202	-	-	-	J	-	-	-	Methyltransferase
DOALAIPI_00616	5.16e-127	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
DOALAIPI_00617	5.12e-123	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
DOALAIPI_00618	0.0	sthIR	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
DOALAIPI_00619	8.77e-200	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
DOALAIPI_00621	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
DOALAIPI_00623	1.52e-282	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
DOALAIPI_00624	4.81e-225	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
DOALAIPI_00625	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DOALAIPI_00626	3.72e-204	-	-	-	EG	-	-	-	EamA-like transporter family
DOALAIPI_00627	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
DOALAIPI_00628	2.21e-310	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
DOALAIPI_00629	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
DOALAIPI_00630	2.31e-148	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
DOALAIPI_00631	4.71e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
DOALAIPI_00632	1.24e-298	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DOALAIPI_00633	1.34e-47	-	-	-	S	-	-	-	Transglycosylase associated protein
DOALAIPI_00634	6.08e-13	-	-	-	S	-	-	-	CsbD-like
DOALAIPI_00635	8.62e-228	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOALAIPI_00636	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
DOALAIPI_00637	2.14e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
DOALAIPI_00638	6.87e-50	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
DOALAIPI_00639	3.82e-192	-	-	-	-	-	-	-	-
DOALAIPI_00640	6.63e-33	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
DOALAIPI_00641	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
DOALAIPI_00642	3.37e-133	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
DOALAIPI_00643	1.78e-97	-	-	-	F	-	-	-	Nudix hydrolase
DOALAIPI_00644	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
DOALAIPI_00645	5.29e-300	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
DOALAIPI_00646	1.97e-293	-	-	-	-	-	-	-	-
DOALAIPI_00647	4.21e-267	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DOALAIPI_00648	5.16e-182	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DOALAIPI_00649	2.49e-187	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DOALAIPI_00650	2.94e-261	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
DOALAIPI_00651	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
DOALAIPI_00652	6.09e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
DOALAIPI_00653	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
DOALAIPI_00654	6.91e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
DOALAIPI_00655	1.24e-99	usp5	-	-	T	-	-	-	universal stress protein
DOALAIPI_00656	1.39e-106	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
DOALAIPI_00657	1.24e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DOALAIPI_00658	3.79e-135	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
DOALAIPI_00659	6.6e-230	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
DOALAIPI_00660	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
DOALAIPI_00661	8.87e-289	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DOALAIPI_00662	1.05e-224	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
DOALAIPI_00663	7.76e-187	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
DOALAIPI_00664	3.75e-119	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
DOALAIPI_00665	1.21e-48	-	-	-	-	-	-	-	-
DOALAIPI_00666	1.76e-68	-	-	-	-	-	-	-	-
DOALAIPI_00667	1.11e-261	-	-	-	-	-	-	-	-
DOALAIPI_00668	2.74e-106	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DOALAIPI_00669	1.38e-175	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
DOALAIPI_00670	4.18e-201	yvgN	-	-	S	-	-	-	Aldo keto reductase
DOALAIPI_00671	4.33e-161	XK27_10500	-	-	K	-	-	-	response regulator
DOALAIPI_00672	5.89e-231	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
DOALAIPI_00673	7.11e-174	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
DOALAIPI_00674	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
DOALAIPI_00675	1.29e-197	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
DOALAIPI_00676	1.7e-209	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
DOALAIPI_00677	1.38e-67	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DOALAIPI_00678	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOALAIPI_00679	8.17e-250	-	-	-	EGP	-	-	-	Major Facilitator
DOALAIPI_00680	4.94e-112	ymdB	-	-	S	-	-	-	Macro domain protein
DOALAIPI_00681	1.01e-140	-	-	-	K	-	-	-	Helix-turn-helix domain
DOALAIPI_00682	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
DOALAIPI_00683	2.1e-64	-	-	-	-	-	-	-	-
DOALAIPI_00684	1.02e-295	-	-	-	S	-	-	-	Putative metallopeptidase domain
DOALAIPI_00685	4.36e-263	-	-	-	S	-	-	-	associated with various cellular activities
DOALAIPI_00686	2.34e-154	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
DOALAIPI_00687	8.5e-86	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
DOALAIPI_00689	6.52e-149	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
DOALAIPI_00690	3.32e-72	-	-	-	-	-	-	-	-
DOALAIPI_00692	1.94e-177	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
DOALAIPI_00693	2.04e-65	-	-	-	-	-	-	-	-
DOALAIPI_00694	1.33e-255	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
DOALAIPI_00695	1.62e-296	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
DOALAIPI_00696	3.61e-316	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
DOALAIPI_00697	2.85e-135	-	-	-	NU	-	-	-	mannosyl-glycoprotein
DOALAIPI_00698	1.33e-182	-	-	-	S	-	-	-	Putative ABC-transporter type IV
DOALAIPI_00699	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
DOALAIPI_00702	7.9e-47	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
DOALAIPI_00703	2.94e-231	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Sodium Bile acid symporter family
DOALAIPI_00704	8.56e-90	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DOALAIPI_00705	1.51e-75	cadX	-	-	K	ko:K21903	-	ko00000,ko03000	Bacterial regulatory protein, arsR family
DOALAIPI_00706	1.96e-130	cadD	-	-	P	-	-	-	Cadmium resistance transporter
DOALAIPI_00707	3.75e-32	-	-	-	K	-	-	-	Helix-turn-helix domain
DOALAIPI_00708	1.28e-41	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
DOALAIPI_00709	2.98e-126	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
DOALAIPI_00711	1.27e-164	-	-	-	M	-	-	-	PFAM NLP P60 protein
DOALAIPI_00712	7.44e-232	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
DOALAIPI_00713	1.18e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
DOALAIPI_00714	3.96e-177	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DOALAIPI_00715	4.94e-122	-	-	-	P	-	-	-	Cadmium resistance transporter
DOALAIPI_00716	1.89e-73	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
DOALAIPI_00717	5.32e-73	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
DOALAIPI_00718	3.78e-169	yceF	-	-	P	ko:K05794	-	ko00000	membrane
DOALAIPI_00719	1.95e-219	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
DOALAIPI_00720	8.21e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
DOALAIPI_00721	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DOALAIPI_00722	1.6e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
DOALAIPI_00723	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
DOALAIPI_00724	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
DOALAIPI_00725	9.5e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
DOALAIPI_00726	7.2e-56	-	-	-	-	-	-	-	-
DOALAIPI_00727	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DOALAIPI_00728	4.76e-44	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DOALAIPI_00729	3.59e-134	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
DOALAIPI_00730	1.37e-196	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
DOALAIPI_00731	4.5e-45	-	-	-	-	-	-	-	-
DOALAIPI_00732	1.16e-202	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DOALAIPI_00733	1.58e-16	-	-	-	G	-	-	-	Major Facilitator
DOALAIPI_00734	1.57e-67	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
DOALAIPI_00735	1.45e-161	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DOALAIPI_00736	3.4e-164	-	-	-	G	-	-	-	Major Facilitator Superfamily
DOALAIPI_00737	3.46e-265	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
DOALAIPI_00738	2.34e-168	-	-	-	S	-	-	-	Alpha beta hydrolase
DOALAIPI_00739	6.89e-278	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
DOALAIPI_00740	6.47e-130	-	-	-	-	-	-	-	-
DOALAIPI_00742	5.48e-157	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
DOALAIPI_00743	7.85e-21	-	-	-	-	-	-	-	-
DOALAIPI_00744	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
DOALAIPI_00745	3.39e-139	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
DOALAIPI_00746	7.05e-113	-	-	-	-	-	-	-	-
DOALAIPI_00747	9.3e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
DOALAIPI_00748	3.67e-259	yttB	-	-	EGP	-	-	-	Major Facilitator
DOALAIPI_00749	2.43e-145	-	-	-	-	-	-	-	-
DOALAIPI_00750	2.6e-33	-	-	-	-	-	-	-	-
DOALAIPI_00751	5.15e-219	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
DOALAIPI_00752	0.0	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DOALAIPI_00753	1.36e-66	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
DOALAIPI_00754	4.81e-50	-	-	-	-	-	-	-	-
DOALAIPI_00755	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DOALAIPI_00756	2.12e-155	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DOALAIPI_00757	5.62e-233	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
DOALAIPI_00758	8.43e-110	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
DOALAIPI_00759	7.01e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
DOALAIPI_00760	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
DOALAIPI_00761	1.89e-80	-	-	-	-	-	-	-	-
DOALAIPI_00762	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DOALAIPI_00764	2.99e-289	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
DOALAIPI_00765	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
DOALAIPI_00766	4.9e-315	-	-	-	E	ko:K03294	-	ko00000	amino acid
DOALAIPI_00767	4.48e-231	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DOALAIPI_00769	2.37e-270	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
DOALAIPI_00770	1.29e-53	-	-	-	S	-	-	-	Cytochrome B5
DOALAIPI_00771	2.41e-07	-	-	-	S	-	-	-	Cytochrome B5
DOALAIPI_00772	6.36e-50	-	-	-	S	-	-	-	Cytochrome B5
DOALAIPI_00773	1.37e-94	-	-	-	S	ko:K02348	-	ko00000	Gnat family
DOALAIPI_00774	2e-14	-	-	-	GM	-	-	-	NmrA-like family
DOALAIPI_00775	4.55e-68	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
DOALAIPI_00776	3.2e-138	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
DOALAIPI_00777	5.31e-99	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
DOALAIPI_00778	1.54e-289	-	-	-	-	-	-	-	-
DOALAIPI_00779	2.18e-268	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DOALAIPI_00780	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
DOALAIPI_00781	1.62e-142	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
DOALAIPI_00782	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
DOALAIPI_00783	4.01e-115	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
DOALAIPI_00784	3.14e-37	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
DOALAIPI_00785	3.51e-253	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
DOALAIPI_00786	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
DOALAIPI_00788	2.33e-165	-	-	-	F	-	-	-	glutamine amidotransferase
DOALAIPI_00789	1.61e-81	-	-	-	-	-	-	-	-
DOALAIPI_00790	1.29e-201	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
DOALAIPI_00791	2.39e-196	-	-	-	K	-	-	-	Transcriptional regulator
DOALAIPI_00792	8.09e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
DOALAIPI_00793	6.71e-220	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
DOALAIPI_00794	3.15e-115	-	-	-	K	-	-	-	Virulence activator alpha C-term
DOALAIPI_00795	4.68e-119	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
DOALAIPI_00796	6.18e-51	-	-	-	C	-	-	-	Flavodoxin
DOALAIPI_00797	8.91e-146	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
DOALAIPI_00798	5.58e-70	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
DOALAIPI_00799	1.94e-13	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
DOALAIPI_00800	3.15e-141	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
DOALAIPI_00801	1.32e-138	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
DOALAIPI_00802	1.42e-304	-	-	-	T	-	-	-	GHKL domain
DOALAIPI_00803	3.03e-158	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
DOALAIPI_00804	1.41e-55	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
DOALAIPI_00807	1.45e-10	-	-	-	S	-	-	-	Bacteriocin class II with double-glycine leader peptide
DOALAIPI_00810	6.41e-270	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
DOALAIPI_00811	2.94e-152	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
DOALAIPI_00812	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
DOALAIPI_00814	3.27e-142	-	-	-	I	-	-	-	Acid phosphatase homologues
DOALAIPI_00815	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
DOALAIPI_00816	1.13e-291	-	-	-	P	-	-	-	Chloride transporter, ClC family
DOALAIPI_00817	1.29e-149	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
DOALAIPI_00818	3.39e-187	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
DOALAIPI_00819	1.6e-179	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DOALAIPI_00820	1.23e-67	-	-	-	-	-	-	-	-
DOALAIPI_00821	0.0	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
DOALAIPI_00822	2.9e-149	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
DOALAIPI_00823	1.32e-101	-	-	-	-	-	-	-	-
DOALAIPI_00824	1.56e-227	-	-	-	-	-	-	-	-
DOALAIPI_00825	2.92e-233	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
DOALAIPI_00826	6.57e-178	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
DOALAIPI_00827	4.36e-167	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOALAIPI_00828	2.64e-103	-	-	-	S	-	-	-	Flavodoxin
DOALAIPI_00829	2.29e-84	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
DOALAIPI_00830	9.9e-49	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
DOALAIPI_00831	3.17e-280	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
DOALAIPI_00832	5.54e-212	-	-	-	H	-	-	-	geranyltranstransferase activity
DOALAIPI_00833	3.85e-234	-	-	-	-	-	-	-	-
DOALAIPI_00834	3.11e-26	-	-	-	-	-	-	-	-
DOALAIPI_00835	2.22e-151	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
DOALAIPI_00836	8.92e-240	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
DOALAIPI_00837	6.37e-60	-	-	-	-	-	-	-	-
DOALAIPI_00838	4.78e-135	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
DOALAIPI_00839	2.28e-108	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
DOALAIPI_00840	8.56e-289	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
DOALAIPI_00841	1.85e-104	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
DOALAIPI_00842	2.43e-241	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
DOALAIPI_00843	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DOALAIPI_00844	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
DOALAIPI_00845	7.3e-131	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
DOALAIPI_00846	4.68e-168	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
DOALAIPI_00847	2.67e-196	-	-	-	EG	-	-	-	EamA-like transporter family
DOALAIPI_00848	1.15e-152	-	-	-	L	-	-	-	Integrase
DOALAIPI_00849	7.24e-204	rssA	-	-	S	-	-	-	Phospholipase, patatin family
DOALAIPI_00851	3.01e-272	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
DOALAIPI_00852	1.18e-55	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
DOALAIPI_00853	3.42e-258	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DOALAIPI_00855	1.76e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DOALAIPI_00856	9.59e-101	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
DOALAIPI_00857	1.97e-228	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DOALAIPI_00858	2.51e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOALAIPI_00859	5.38e-201	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
DOALAIPI_00860	1.49e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
DOALAIPI_00861	5.51e-283	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DOALAIPI_00862	2.33e-91	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DOALAIPI_00863	2.29e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DOALAIPI_00864	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
DOALAIPI_00865	1.25e-146	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
DOALAIPI_00866	1.46e-163	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
DOALAIPI_00867	6.52e-219	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
DOALAIPI_00868	1.25e-124	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
DOALAIPI_00869	8.11e-263	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
DOALAIPI_00870	3.7e-19	-	-	-	-	-	-	-	-
DOALAIPI_00871	2.99e-115	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
DOALAIPI_00872	3.12e-250	-	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
DOALAIPI_00873	2.53e-146	-	-	-	S	-	-	-	Membrane
DOALAIPI_00874	1.82e-160	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
DOALAIPI_00875	9.38e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DOALAIPI_00876	6.43e-204	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
DOALAIPI_00878	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
DOALAIPI_00879	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
DOALAIPI_00882	0.0	-	-	-	M	-	-	-	family 8
DOALAIPI_00883	0.0	-	-	-	M	-	-	-	family 8
DOALAIPI_00884	1.36e-26	-	-	-	M	-	-	-	family 8
DOALAIPI_00886	0.0	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
DOALAIPI_00887	0.0	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
DOALAIPI_00888	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DOALAIPI_00889	2.85e-211	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
DOALAIPI_00890	0.0	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
DOALAIPI_00891	0.0	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
DOALAIPI_00892	6.21e-266	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
DOALAIPI_00893	4.57e-110	-	-	-	S	-	-	-	glycosyl transferase family 2
DOALAIPI_00894	2.85e-242	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
DOALAIPI_00895	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
DOALAIPI_00896	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
DOALAIPI_00897	6.57e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
DOALAIPI_00898	4.58e-191	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
DOALAIPI_00899	1.97e-151	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
DOALAIPI_00901	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DOALAIPI_00902	1.59e-211	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
DOALAIPI_00903	4.44e-292	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
DOALAIPI_00904	3.69e-167	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
DOALAIPI_00905	3.29e-282	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
DOALAIPI_00906	3.17e-184	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Putative cyclase
DOALAIPI_00907	6.63e-203	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
DOALAIPI_00908	1.49e-224	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
DOALAIPI_00909	5.73e-57	-	-	-	-	-	-	-	-
DOALAIPI_00910	1.62e-173	-	-	-	-	-	-	-	-
DOALAIPI_00917	7.73e-109	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
DOALAIPI_00918	1.4e-111	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	site-specific DNA-methyltransferase (adenine-specific) activity
DOALAIPI_00919	2.96e-220	bcgIA	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	site-specific DNA-methyltransferase (adenine-specific) activity
DOALAIPI_00920	3.44e-195	-	-	-	L	-	-	-	HNH nucleases
DOALAIPI_00921	5.66e-101	-	-	-	L	-	-	-	Phage terminase, small subunit
DOALAIPI_00922	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
DOALAIPI_00924	3.22e-307	-	-	-	S	-	-	-	Phage portal protein
DOALAIPI_00925	1.61e-144	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
DOALAIPI_00926	2.72e-261	-	-	-	S	-	-	-	Phage capsid family
DOALAIPI_00927	2.83e-90	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
DOALAIPI_00928	6.4e-54	-	-	-	S	-	-	-	Phage head-tail joining protein
DOALAIPI_00929	1.85e-82	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
DOALAIPI_00930	1.7e-101	-	-	-	-	-	-	-	-
DOALAIPI_00931	4.9e-151	-	-	-	-	-	-	-	-
DOALAIPI_00932	4.31e-76	-	-	-	-	-	-	-	-
DOALAIPI_00933	9.13e-34	-	-	-	-	-	-	-	-
DOALAIPI_00934	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
DOALAIPI_00935	2.25e-205	-	-	-	S	-	-	-	Phage tail protein
DOALAIPI_00936	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
DOALAIPI_00938	3.58e-140	-	-	-	M	-	-	-	CotH kinase protein
DOALAIPI_00940	1.28e-48	-	-	-	S	-	-	-	Bacteriophage holin family
DOALAIPI_00941	4.49e-72	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
DOALAIPI_00942	6.9e-258	-	-	-	M	-	-	-	hydrolase, family 25
DOALAIPI_00943	4.25e-159	-	-	-	L	-	-	-	Helix-turn-helix domain
DOALAIPI_00944	8.72e-91	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
DOALAIPI_00945	4.85e-94	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
DOALAIPI_00946	3.16e-22	-	-	-	-	-	-	-	-
DOALAIPI_00947	4e-208	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DOALAIPI_00948	8.36e-146	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
DOALAIPI_00949	3.04e-71	-	-	-	-	-	-	-	-
DOALAIPI_00950	6.69e-112	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
DOALAIPI_00959	8.5e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DOALAIPI_00960	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DOALAIPI_00961	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
DOALAIPI_00962	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DOALAIPI_00963	2.43e-264	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DOALAIPI_00964	5.41e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
DOALAIPI_00965	2.95e-262	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DOALAIPI_00966	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DOALAIPI_00967	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DOALAIPI_00968	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
DOALAIPI_00969	9.42e-111	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DOALAIPI_00970	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DOALAIPI_00971	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
DOALAIPI_00972	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
DOALAIPI_00973	3.65e-308	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
DOALAIPI_00974	1.87e-269	yttB	-	-	EGP	-	-	-	Major Facilitator
DOALAIPI_00975	1.76e-77	-	-	-	-	-	-	-	-
DOALAIPI_00976	2.17e-209	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
DOALAIPI_00977	1.95e-127	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
DOALAIPI_00979	1.88e-96	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
DOALAIPI_00980	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
DOALAIPI_00982	1.29e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
DOALAIPI_00983	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DOALAIPI_00984	0.0	yycH	-	-	S	-	-	-	YycH protein
DOALAIPI_00985	3.54e-193	yycI	-	-	S	-	-	-	YycH protein
DOALAIPI_00986	2.52e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
DOALAIPI_00987	2.87e-288	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
DOALAIPI_00988	5.79e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
DOALAIPI_00989	6.32e-227	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
DOALAIPI_00990	7.54e-115	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DOALAIPI_00992	9.98e-24	-	-	-	-	-	-	-	-
DOALAIPI_00993	1.98e-26	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
DOALAIPI_00994	1.27e-115	-	-	-	J	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
DOALAIPI_00995	1.8e-74	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DOALAIPI_00996	1.94e-247	flp	-	-	V	-	-	-	Beta-lactamase
DOALAIPI_00997	4.31e-123	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
DOALAIPI_00998	6.89e-159	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
DOALAIPI_01000	1.19e-141	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
DOALAIPI_01001	1.84e-56	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
DOALAIPI_01002	1.44e-42	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
DOALAIPI_01003	1.19e-51	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
DOALAIPI_01005	2.79e-199	yocS	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
DOALAIPI_01006	8.13e-51	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
DOALAIPI_01007	0.0	ilvD	4.2.1.9	-	EG	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
DOALAIPI_01008	1.17e-37	-	-	-	L	-	-	-	PFAM Integrase catalytic region
DOALAIPI_01009	1.7e-110	-	-	-	L	-	-	-	PFAM Integrase catalytic region
DOALAIPI_01010	0.0	-	-	-	S	-	-	-	amidohydrolase
DOALAIPI_01011	5.51e-205	-	-	-	S	-	-	-	reductase
DOALAIPI_01012	1.26e-113	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
DOALAIPI_01013	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
DOALAIPI_01014	6.05e-314	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
DOALAIPI_01015	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DOALAIPI_01016	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
DOALAIPI_01017	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DOALAIPI_01018	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DOALAIPI_01019	4.11e-175	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
DOALAIPI_01020	1.71e-74	cps3I	-	-	G	-	-	-	Acyltransferase family
DOALAIPI_01021	1.16e-93	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
DOALAIPI_01022	5.94e-291	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
DOALAIPI_01023	2.02e-268	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
DOALAIPI_01024	4.83e-38	-	-	-	-	-	-	-	-
DOALAIPI_01025	2.19e-86	-	-	-	S	-	-	-	Acyltransferase family
DOALAIPI_01026	8.59e-192	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
DOALAIPI_01027	4.88e-99	-	-	-	M	-	-	-	Core-2/I-Branching enzyme
DOALAIPI_01028	1.82e-79	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
DOALAIPI_01029	2.63e-36	-	-	-	M	-	-	-	biosynthesis protein
DOALAIPI_01030	3.07e-115	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
DOALAIPI_01031	9.18e-87	-	-	-	-	-	-	-	-
DOALAIPI_01032	8.1e-153	-	-	-	M	-	-	-	Bacterial sugar transferase
DOALAIPI_01033	8.58e-220	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
DOALAIPI_01034	6.67e-190	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
DOALAIPI_01035	4.75e-174	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
DOALAIPI_01036	2.97e-41	-	-	-	-	-	-	-	-
DOALAIPI_01037	4.23e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
DOALAIPI_01038	1.51e-202	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
DOALAIPI_01039	0.0	potE	-	-	E	-	-	-	Amino Acid
DOALAIPI_01040	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
DOALAIPI_01041	1.97e-280	arcT	-	-	E	-	-	-	Aminotransferase
DOALAIPI_01042	5.8e-215	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
DOALAIPI_01043	2.24e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
DOALAIPI_01044	8.59e-98	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
DOALAIPI_01045	5.13e-60	-	-	-	-	-	-	-	-
DOALAIPI_01046	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
DOALAIPI_01047	1.81e-41	-	-	-	-	-	-	-	-
DOALAIPI_01048	7.67e-63	-	-	-	-	-	-	-	-
DOALAIPI_01049	2.41e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DOALAIPI_01050	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
DOALAIPI_01051	2.69e-295	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
DOALAIPI_01052	4.12e-234	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
DOALAIPI_01053	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
DOALAIPI_01054	3.97e-125	-	-	-	-	-	-	-	-
DOALAIPI_01055	3.09e-35	-	-	-	-	-	-	-	-
DOALAIPI_01056	2.71e-81	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
DOALAIPI_01057	1.32e-117	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
DOALAIPI_01059	5.29e-65	-	-	-	-	-	-	-	-
DOALAIPI_01060	2.13e-88	-	-	-	S	-	-	-	Belongs to the HesB IscA family
DOALAIPI_01061	8.96e-223	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
DOALAIPI_01062	6.97e-109	-	-	-	F	-	-	-	Hydrolase, NUDIX family
DOALAIPI_01063	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DOALAIPI_01064	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DOALAIPI_01065	1.56e-138	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DOALAIPI_01066	4.76e-213	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
DOALAIPI_01067	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DOALAIPI_01068	1.11e-206	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
DOALAIPI_01073	3.52e-06	-	-	-	-	-	-	-	-
DOALAIPI_01074	1.55e-09	-	-	-	K	-	-	-	Helix-turn-helix domain
DOALAIPI_01075	2.5e-52	-	-	-	D	-	-	-	nuclear chromosome segregation
DOALAIPI_01076	4.81e-41	-	-	-	-	-	-	-	-
DOALAIPI_01077	1.1e-05	-	-	-	-	-	-	-	-
DOALAIPI_01085	3.93e-98	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
DOALAIPI_01086	9.87e-190	-	-	-	-	-	-	-	-
DOALAIPI_01087	0.0	-	-	-	-	-	-	-	-
DOALAIPI_01089	8.38e-28	-	-	-	-	-	-	-	-
DOALAIPI_01090	3.11e-158	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DOALAIPI_01091	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
DOALAIPI_01092	1.98e-163	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
DOALAIPI_01093	5e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DOALAIPI_01094	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DOALAIPI_01095	1.11e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DOALAIPI_01096	2.47e-65	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
DOALAIPI_01097	5.39e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
DOALAIPI_01098	2.29e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DOALAIPI_01099	1.11e-198	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DOALAIPI_01100	4.67e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
DOALAIPI_01101	1.08e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
DOALAIPI_01102	4.83e-173	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
DOALAIPI_01103	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
DOALAIPI_01104	1.87e-213	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
DOALAIPI_01105	6.81e-222	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DOALAIPI_01106	7.59e-268	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
DOALAIPI_01107	2.62e-201	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
DOALAIPI_01108	9.54e-113	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
DOALAIPI_01109	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
DOALAIPI_01110	7.05e-199	-	-	-	S	-	-	-	Fic/DOC family
DOALAIPI_01113	3.36e-30	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
DOALAIPI_01114	3.83e-90	M1-798	-	-	K	-	-	-	Rhodanese Homology Domain
DOALAIPI_01115	2.9e-33	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	cell redox homeostasis
DOALAIPI_01116	3.6e-176	trxB	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Glucose inhibited division protein A
DOALAIPI_01117	3.53e-123	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	dithiol-disulfide isomerase involved in polyketide biosynthesis
DOALAIPI_01119	1.59e-51	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
DOALAIPI_01120	7.72e-49	ytpP	-	-	CO	-	-	-	Thioredoxin
DOALAIPI_01121	1.07e-66	-	-	-	L	-	-	-	Transposase
DOALAIPI_01122	7.52e-74	-	-	-	-	-	-	-	-
DOALAIPI_01123	3.46e-76	-	-	-	IQ	-	-	-	dehydrogenase reductase
DOALAIPI_01124	3.58e-61	-	-	-	IQ	-	-	-	dehydrogenase reductase
DOALAIPI_01125	9.51e-51	-	-	-	-	-	-	-	-
DOALAIPI_01126	5.67e-149	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
DOALAIPI_01127	2.3e-52	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
DOALAIPI_01128	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
DOALAIPI_01129	2.4e-233	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DOALAIPI_01131	1.76e-132	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
DOALAIPI_01132	7.3e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
DOALAIPI_01133	5.87e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DOALAIPI_01135	9.77e-230	ydhF	-	-	S	-	-	-	Aldo keto reductase
DOALAIPI_01136	2.26e-110	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
DOALAIPI_01137	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
DOALAIPI_01139	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
DOALAIPI_01140	2.84e-73	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
DOALAIPI_01141	7.41e-163	-	-	-	-	-	-	-	-
DOALAIPI_01142	1.31e-161	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
DOALAIPI_01143	0.0	cadA	-	-	P	-	-	-	P-type ATPase
DOALAIPI_01144	4.27e-273	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DOALAIPI_01145	7.8e-97	ywnA	-	-	K	-	-	-	Transcriptional regulator
DOALAIPI_01146	3.07e-208	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
DOALAIPI_01147	5.77e-140	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DOALAIPI_01148	1.75e-181	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
DOALAIPI_01149	1.96e-138	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
DOALAIPI_01150	5.22e-102	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
DOALAIPI_01151	2e-219	eriC	-	-	P	ko:K03281	-	ko00000	chloride
DOALAIPI_01152	4.76e-35	eriC	-	-	P	ko:K03281	-	ko00000	chloride
DOALAIPI_01153	4.82e-276	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
DOALAIPI_01154	7.46e-140	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DOALAIPI_01155	4.92e-244	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DOALAIPI_01156	4.34e-200	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
DOALAIPI_01157	1.21e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
DOALAIPI_01158	5.93e-281	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
DOALAIPI_01159	5.98e-55	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
DOALAIPI_01160	1.91e-150	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DOALAIPI_01161	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
DOALAIPI_01162	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DOALAIPI_01164	8.49e-66	-	-	-	L	-	-	-	Transposase, IS116 IS110 IS902 family
DOALAIPI_01165	2.47e-250	eriC	-	-	P	ko:K03281	-	ko00000	chloride
DOALAIPI_01166	3.69e-259	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
DOALAIPI_01167	0.0	-	-	-	L	-	-	-	DNA helicase
DOALAIPI_01168	1.17e-105	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
DOALAIPI_01169	8.47e-241	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
DOALAIPI_01170	2.26e-242	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
DOALAIPI_01171	1.03e-213	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
DOALAIPI_01172	6.78e-289	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
DOALAIPI_01173	4.46e-227	-	-	-	-	-	-	-	-
DOALAIPI_01174	1.69e-167	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
DOALAIPI_01176	1.59e-206	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
DOALAIPI_01177	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DOALAIPI_01178	2.07e-197	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
DOALAIPI_01179	2.87e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DOALAIPI_01180	1.25e-206	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DOALAIPI_01181	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
DOALAIPI_01182	2.34e-204	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DOALAIPI_01183	1.17e-214	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
DOALAIPI_01184	2.81e-157	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
DOALAIPI_01185	3.54e-165	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
DOALAIPI_01186	3.84e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
DOALAIPI_01187	3.17e-314	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DOALAIPI_01188	9.36e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DOALAIPI_01189	3.1e-101	-	-	-	-	-	-	-	-
DOALAIPI_01190	2.21e-188	yidA	-	-	S	-	-	-	hydrolase
DOALAIPI_01191	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
DOALAIPI_01192	2.79e-187	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
DOALAIPI_01193	9.28e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
DOALAIPI_01194	1.04e-85	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
DOALAIPI_01195	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DOALAIPI_01196	3.89e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DOALAIPI_01197	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
DOALAIPI_01198	4.56e-303	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DOALAIPI_01199	1.31e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DOALAIPI_01200	2.48e-161	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
DOALAIPI_01201	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
DOALAIPI_01202	2.41e-190	-	-	-	G	-	-	-	Right handed beta helix region
DOALAIPI_01203	4.1e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DOALAIPI_01204	3.34e-209	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
DOALAIPI_01205	3.7e-155	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
DOALAIPI_01206	1.15e-113	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DOALAIPI_01207	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
DOALAIPI_01208	2.61e-204	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
DOALAIPI_01209	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DOALAIPI_01210	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
DOALAIPI_01211	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
DOALAIPI_01212	1.92e-209	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
DOALAIPI_01213	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DOALAIPI_01214	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DOALAIPI_01215	3.03e-298	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
DOALAIPI_01216	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DOALAIPI_01217	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
DOALAIPI_01218	2.2e-79	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DOALAIPI_01219	3.78e-270	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DOALAIPI_01220	1.3e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
DOALAIPI_01221	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
DOALAIPI_01222	4.9e-303	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
DOALAIPI_01223	3.41e-187	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
DOALAIPI_01224	7.75e-145	-	-	-	S	-	-	-	(CBS) domain
DOALAIPI_01225	3.25e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DOALAIPI_01226	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DOALAIPI_01227	1.01e-52	yabO	-	-	J	-	-	-	S4 domain protein
DOALAIPI_01228	8.69e-76	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
DOALAIPI_01229	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
DOALAIPI_01230	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DOALAIPI_01231	3.68e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
DOALAIPI_01232	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DOALAIPI_01233	9.26e-218	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DOALAIPI_01234	2.08e-239	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DOALAIPI_01235	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
DOALAIPI_01236	0.0	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
DOALAIPI_01237	0.0	-	-	-	O	-	-	-	Arylsulfotransferase (ASST)
DOALAIPI_01239	5.12e-120	-	-	-	-	-	-	-	-
DOALAIPI_01240	7.05e-54	-	-	-	-	-	-	-	-
DOALAIPI_01241	8.53e-60	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DOALAIPI_01242	5.83e-133	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
DOALAIPI_01243	3.69e-92	-	-	-	-	-	-	-	-
DOALAIPI_01244	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
DOALAIPI_01245	2.93e-127	-	-	-	L	-	-	-	nuclease
DOALAIPI_01246	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
DOALAIPI_01247	2.25e-265	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
DOALAIPI_01248	9.09e-25	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
DOALAIPI_01249	9.06e-185	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
DOALAIPI_01250	0.0	snf	-	-	KL	-	-	-	domain protein
DOALAIPI_01251	0.0	snf	-	-	KL	-	-	-	domain protein
DOALAIPI_01253	1.31e-48	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
DOALAIPI_01254	9.54e-85	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
DOALAIPI_01255	9.07e-150	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DOALAIPI_01256	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
DOALAIPI_01257	7.56e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
DOALAIPI_01258	8.34e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
DOALAIPI_01259	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DOALAIPI_01260	2.07e-199	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DOALAIPI_01261	4.46e-124	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DOALAIPI_01262	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DOALAIPI_01263	3.09e-304	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
DOALAIPI_01264	2.46e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
DOALAIPI_01265	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DOALAIPI_01266	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
DOALAIPI_01267	5.46e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DOALAIPI_01268	2.71e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
DOALAIPI_01269	1.05e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
DOALAIPI_01270	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
DOALAIPI_01271	4.9e-158	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DOALAIPI_01272	9.9e-144	yqeK	-	-	H	-	-	-	Hydrolase, HD family
DOALAIPI_01273	2.69e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DOALAIPI_01274	4.31e-177	yqeM	-	-	Q	-	-	-	Methyltransferase
DOALAIPI_01275	7.96e-273	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
DOALAIPI_01276	1.43e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
DOALAIPI_01277	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
DOALAIPI_01278	8.57e-88	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DOALAIPI_01279	3.66e-65	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
DOALAIPI_01280	2.74e-37	-	-	-	-	-	-	-	-
DOALAIPI_01281	2.63e-232	yueF	-	-	S	-	-	-	AI-2E family transporter
DOALAIPI_01282	8.34e-302	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
DOALAIPI_01283	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DOALAIPI_01284	2.26e-126	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
DOALAIPI_01285	1.71e-70	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DOALAIPI_01287	7.12e-48	-	-	-	S	-	-	-	Acyltransferase family
DOALAIPI_01289	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
DOALAIPI_01290	8.05e-134	-	-	-	S	-	-	-	Peptidase, M23
DOALAIPI_01292	2.41e-84	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
DOALAIPI_01293	5.67e-198	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DOALAIPI_01294	1.77e-142	-	-	-	-	-	-	-	-
DOALAIPI_01295	9.48e-183	-	-	-	G	-	-	-	MucBP domain
DOALAIPI_01296	1.56e-130	-	-	-	S	-	-	-	Pfam:DUF3816
DOALAIPI_01297	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
DOALAIPI_01298	5.62e-37	-	-	-	-	-	-	-	-
DOALAIPI_01299	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
DOALAIPI_01300	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DOALAIPI_01301	2.1e-289	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
DOALAIPI_01302	7.98e-253	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
DOALAIPI_01303	5.39e-228	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DOALAIPI_01304	1.97e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
DOALAIPI_01305	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
DOALAIPI_01306	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
DOALAIPI_01307	9.5e-239	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
DOALAIPI_01308	9.85e-59	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
DOALAIPI_01309	1.06e-50	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DOALAIPI_01310	9.33e-142	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DOALAIPI_01311	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
DOALAIPI_01312	5.42e-110	-	-	-	-	-	-	-	-
DOALAIPI_01313	5.32e-206	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
DOALAIPI_01314	6.09e-70	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
DOALAIPI_01315	2.02e-47	-	-	-	-	-	-	-	-
DOALAIPI_01316	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
DOALAIPI_01317	1.75e-237	-	-	-	M	-	-	-	MobA-like NTP transferase domain
DOALAIPI_01318	3.87e-109	-	-	-	M	-	-	-	MobA-like NTP transferase domain
DOALAIPI_01319	1.23e-206	cudT	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
DOALAIPI_01322	3.17e-261	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DOALAIPI_01323	1.45e-197	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
DOALAIPI_01325	7.47e-31	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
DOALAIPI_01326	1.09e-64	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
DOALAIPI_01328	1.04e-91	-	-	-	S	-	-	-	TM2 domain
DOALAIPI_01330	3.22e-121	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
DOALAIPI_01331	8.43e-159	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
DOALAIPI_01332	6.95e-185	epsB	-	-	M	-	-	-	biosynthesis protein
DOALAIPI_01333	1.61e-227	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
DOALAIPI_01334	1.37e-90	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
DOALAIPI_01335	1.49e-165	-	-	-	-	-	-	-	-
DOALAIPI_01336	3.35e-131	-	-	-	K	-	-	-	DNA-templated transcription, initiation
DOALAIPI_01337	1.89e-47	-	-	-	-	-	-	-	-
DOALAIPI_01338	1.84e-105	-	-	-	-	-	-	-	-
DOALAIPI_01339	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DOALAIPI_01340	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
DOALAIPI_01341	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
DOALAIPI_01342	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DOALAIPI_01344	4.12e-56	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
DOALAIPI_01345	6.49e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
DOALAIPI_01346	1.4e-147	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
DOALAIPI_01347	3.09e-211	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DOALAIPI_01348	1.75e-29	-	-	-	-	-	-	-	-
DOALAIPI_01349	9.72e-118	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
DOALAIPI_01350	6.65e-194	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
DOALAIPI_01351	4.77e-65	yrvD	-	-	S	-	-	-	Pfam:DUF1049
DOALAIPI_01353	2.52e-263	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DOALAIPI_01354	8.74e-95	-	-	-	-	-	-	-	-
DOALAIPI_01355	4.07e-43	-	-	-	-	-	-	-	-
DOALAIPI_01357	4.92e-99	-	-	-	-	-	-	-	-
DOALAIPI_01360	6.3e-63	-	-	-	S	-	-	-	protein disulfide oxidoreductase activity
DOALAIPI_01361	5.89e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF739)
DOALAIPI_01365	3.11e-71	-	-	-	-	-	-	-	-
DOALAIPI_01366	1.71e-80	-	-	-	-	-	-	-	-
DOALAIPI_01367	2.67e-22	-	-	-	-	-	-	-	-
DOALAIPI_01370	1.73e-194	-	-	-	L	-	-	-	DnaD domain protein
DOALAIPI_01371	8.71e-108	-	-	-	M	-	-	-	Glycosyl transferases group 1
DOALAIPI_01372	4.71e-127	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
DOALAIPI_01374	4.45e-49	-	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
DOALAIPI_01375	1.86e-82	-	-	-	S	-	-	-	SPTR Capsular exopolysaccharide biosynthesis protein (Wzm)
DOALAIPI_01376	1.83e-143	cps2J	-	-	S	-	-	-	Polysaccharide biosynthesis protein
DOALAIPI_01377	1.04e-140	-	-	-	M	-	-	-	Glycosyl transferases group 1
DOALAIPI_01378	2.44e-142	-	-	-	-	-	-	-	-
DOALAIPI_01379	5.06e-42	-	-	-	S	-	-	-	Glycosyltransferase like family 2
DOALAIPI_01380	2.29e-116	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
DOALAIPI_01381	1.17e-74	-	-	-	L	-	-	-	Helix-turn-helix domain
DOALAIPI_01382	6.39e-38	-	-	-	L	-	-	-	Helix-turn-helix domain
DOALAIPI_01384	0.000102	-	-	-	S	-	-	-	Putative cell wall binding repeat
DOALAIPI_01385	3.17e-39	-	-	-	L	-	-	-	Transposase
DOALAIPI_01386	1.63e-205	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DOALAIPI_01387	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DOALAIPI_01388	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DOALAIPI_01389	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DOALAIPI_01390	2.79e-153	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type II secretory pathway prepilin signal peptidase PulO and related peptidases
DOALAIPI_01391	4.91e-265	-	-	-	-	-	-	-	-
DOALAIPI_01392	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DOALAIPI_01393	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DOALAIPI_01394	2.09e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DOALAIPI_01395	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DOALAIPI_01396	2.81e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
DOALAIPI_01397	1.8e-249	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
DOALAIPI_01398	5.66e-230	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
DOALAIPI_01399	7.59e-14	-	-	-	-	-	-	-	-
DOALAIPI_01404	1.8e-59	-	-	-	S	-	-	-	calcium ion binding
DOALAIPI_01406	5.75e-37	-	-	-	-	-	-	-	-
DOALAIPI_01407	2.41e-20	-	-	-	-	-	-	-	-
DOALAIPI_01408	2.57e-23	-	-	-	S	-	-	-	sequence-specific DNA binding
DOALAIPI_01409	2.86e-53	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
DOALAIPI_01415	1.11e-149	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
DOALAIPI_01416	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
DOALAIPI_01417	1.22e-07	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
DOALAIPI_01418	6.58e-152	-	-	-	I	-	-	-	phosphatase
DOALAIPI_01419	1.06e-106	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
DOALAIPI_01420	1.54e-168	-	-	-	S	-	-	-	Putative threonine/serine exporter
DOALAIPI_01421	8.84e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
DOALAIPI_01422	1.15e-161	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
DOALAIPI_01423	2e-212	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
DOALAIPI_01424	6.28e-153	-	-	-	S	-	-	-	membrane
DOALAIPI_01425	2.34e-142	-	-	-	S	-	-	-	VIT family
DOALAIPI_01426	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
DOALAIPI_01427	8.01e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DOALAIPI_01428	1.1e-194	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DOALAIPI_01429	7.44e-143	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DOALAIPI_01430	3.65e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DOALAIPI_01431	3.69e-278	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DOALAIPI_01432	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DOALAIPI_01433	2e-75	-	-	-	-	-	-	-	-
DOALAIPI_01434	4.39e-97	-	-	-	K	-	-	-	MerR HTH family regulatory protein
DOALAIPI_01435	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
DOALAIPI_01436	3.46e-156	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
DOALAIPI_01437	2.64e-209	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DOALAIPI_01439	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DOALAIPI_01440	2.28e-133	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
DOALAIPI_01441	2.07e-236	-	-	-	I	-	-	-	Alpha beta
DOALAIPI_01442	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
DOALAIPI_01443	1.91e-152	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
DOALAIPI_01444	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
DOALAIPI_01445	4e-202	-	-	-	K	-	-	-	LysR family
DOALAIPI_01446	1.25e-143	-	-	-	I	-	-	-	Alpha/beta hydrolase family
DOALAIPI_01447	1.27e-192	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
DOALAIPI_01448	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
DOALAIPI_01449	1.56e-202	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
DOALAIPI_01450	4.97e-54	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
DOALAIPI_01451	8.06e-189	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
DOALAIPI_01452	3.84e-222	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
DOALAIPI_01453	1.24e-157	citR	-	-	K	-	-	-	sugar-binding domain protein
DOALAIPI_01454	8.69e-216	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
DOALAIPI_01455	6.01e-166	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
DOALAIPI_01456	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
DOALAIPI_01457	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
DOALAIPI_01458	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
DOALAIPI_01459	2.22e-206	mleR	-	-	K	-	-	-	LysR family
DOALAIPI_01460	1.66e-143	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DOALAIPI_01461	1.91e-263	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
DOALAIPI_01462	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
DOALAIPI_01463	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
DOALAIPI_01464	8.23e-39	-	-	-	-	-	-	-	-
DOALAIPI_01465	1.23e-253	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
DOALAIPI_01466	6.26e-96	-	-	-	-	-	-	-	-
DOALAIPI_01467	6.45e-284	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
DOALAIPI_01468	5.58e-178	-	-	-	V	-	-	-	Beta-lactamase enzyme family
DOALAIPI_01469	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
DOALAIPI_01470	2.2e-272	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
DOALAIPI_01471	0.0	arcT	-	-	E	-	-	-	Dipeptidase
DOALAIPI_01472	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
DOALAIPI_01473	2.1e-218	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
DOALAIPI_01474	5.66e-29	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
DOALAIPI_01475	7.04e-104	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
DOALAIPI_01476	1.27e-140	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DOALAIPI_01477	1.6e-211	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
DOALAIPI_01478	1.1e-218	-	-	-	S	-	-	-	Conserved hypothetical protein 698
DOALAIPI_01479	1.31e-108	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
DOALAIPI_01480	8.5e-213	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
DOALAIPI_01481	2.69e-228	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
DOALAIPI_01482	6.6e-294	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
DOALAIPI_01483	4.4e-113	-	-	-	Q	-	-	-	Methyltransferase
DOALAIPI_01484	3.26e-151	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
DOALAIPI_01485	3.74e-302	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
DOALAIPI_01486	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
DOALAIPI_01487	8.49e-108	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
DOALAIPI_01488	3.32e-287	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
DOALAIPI_01489	1.43e-309	-	-	-	M	-	-	-	Glycosyl transferase
DOALAIPI_01491	8.84e-186	-	-	-	-	-	-	-	-
DOALAIPI_01492	2.89e-160	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
DOALAIPI_01493	5.22e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DOALAIPI_01494	6.08e-196	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
DOALAIPI_01495	5.34e-193	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
DOALAIPI_01496	1.91e-202	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
DOALAIPI_01497	2.06e-170	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
DOALAIPI_01498	6.63e-174	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DOALAIPI_01499	6.72e-183	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
DOALAIPI_01500	2.61e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
DOALAIPI_01501	4.2e-96	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DOALAIPI_01502	1.65e-55	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DOALAIPI_01503	2.25e-207	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
DOALAIPI_01504	3.44e-146	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DOALAIPI_01505	2.3e-167	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
DOALAIPI_01506	2.54e-101	ureE	-	-	O	ko:K03187	-	ko00000	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DOALAIPI_01507	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Amidohydrolase family
DOALAIPI_01508	2.83e-84	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease beta subunit
DOALAIPI_01509	3.44e-60	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease, gamma subunit
DOALAIPI_01510	9.52e-124	-	-	-	S	-	-	-	AmiS/UreI family transporter
DOALAIPI_01511	1.06e-276	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
DOALAIPI_01513	1.24e-215	-	-	-	-	-	-	-	-
DOALAIPI_01514	2.61e-123	-	-	-	K	-	-	-	acetyltransferase
DOALAIPI_01515	3.3e-31	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DOALAIPI_01516	4.05e-31	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DOALAIPI_01518	4.56e-228	-	-	-	-	-	-	-	-
DOALAIPI_01519	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DOALAIPI_01520	4.94e-233	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
DOALAIPI_01521	1.81e-89	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
DOALAIPI_01522	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
DOALAIPI_01523	6.5e-71	-	-	-	-	-	-	-	-
DOALAIPI_01524	3.54e-148	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
DOALAIPI_01525	5.23e-311	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DOALAIPI_01526	2.88e-125	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
DOALAIPI_01527	5.53e-284	potE	-	-	E	-	-	-	Amino Acid
DOALAIPI_01528	3.86e-167	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
DOALAIPI_01529	0.000617	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
DOALAIPI_01531	9.22e-104	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
DOALAIPI_01532	2.02e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DOALAIPI_01533	2.7e-155	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
DOALAIPI_01534	4.87e-264	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
DOALAIPI_01535	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DOALAIPI_01536	2.41e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
DOALAIPI_01537	1.29e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
DOALAIPI_01538	1.46e-196	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DOALAIPI_01539	4.11e-223	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DOALAIPI_01540	4e-76	-	-	-	-	-	-	-	-
DOALAIPI_01541	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
DOALAIPI_01542	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
DOALAIPI_01543	1.03e-121	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DOALAIPI_01544	6.7e-205	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
DOALAIPI_01545	2.67e-251	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
DOALAIPI_01547	1.61e-66	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
DOALAIPI_01548	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
DOALAIPI_01549	4.25e-47	-	-	-	M	-	-	-	Rib/alpha-like repeat
DOALAIPI_01550	6.35e-177	-	-	-	IQ	-	-	-	KR domain
DOALAIPI_01551	3.85e-233	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
DOALAIPI_01552	1.69e-233	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
DOALAIPI_01553	1.19e-145	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
DOALAIPI_01554	1.78e-316	yagE	-	-	E	-	-	-	amino acid
DOALAIPI_01555	1.26e-303	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
DOALAIPI_01556	1.77e-69	-	-	-	M	-	-	-	Peptidase_C39 like family
DOALAIPI_01557	5.69e-105	-	-	-	-	-	-	-	-
DOALAIPI_01558	1.68e-166	-	-	-	M	-	-	-	Lysin motif
DOALAIPI_01559	3.8e-255	-	-	-	EGP	-	-	-	Major Facilitator
DOALAIPI_01560	1.36e-126	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
DOALAIPI_01561	3.38e-294	-	-	-	L	-	-	-	Integrase core domain
DOALAIPI_01562	7.15e-179	-	-	-	L	-	-	-	Bacterial dnaA protein
DOALAIPI_01582	6.57e-163	-	-	-	L	-	-	-	Helix-turn-helix domain
DOALAIPI_01583	3.89e-156	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
DOALAIPI_01584	1.35e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DOALAIPI_01585	5.1e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DOALAIPI_01586	7.68e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
DOALAIPI_01587	5.52e-139	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
DOALAIPI_01588	1.37e-220	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
DOALAIPI_01589	9.07e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
DOALAIPI_01590	4.3e-143	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
DOALAIPI_01591	7.66e-116	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DOALAIPI_01592	2.44e-245	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DOALAIPI_01593	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
DOALAIPI_01594	1.36e-284	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DOALAIPI_01595	3.87e-300	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
DOALAIPI_01596	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DOALAIPI_01597	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
DOALAIPI_01598	1.49e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
DOALAIPI_01599	4.75e-147	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
DOALAIPI_01600	1.37e-69	-	-	-	M	-	-	-	Lysin motif
DOALAIPI_01601	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
DOALAIPI_01602	3.32e-240	-	-	-	S	-	-	-	Helix-turn-helix domain
DOALAIPI_01603	1.08e-132	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DOALAIPI_01604	3.66e-165	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
DOALAIPI_01605	2.24e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DOALAIPI_01606	1.87e-175	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DOALAIPI_01607	2.49e-84	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DOALAIPI_01608	4.23e-214	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
DOALAIPI_01609	3.23e-216	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
DOALAIPI_01610	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
DOALAIPI_01611	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
DOALAIPI_01612	7.81e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
DOALAIPI_01613	1.3e-300	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
DOALAIPI_01614	7.53e-201	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DOALAIPI_01615	2.91e-165	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
DOALAIPI_01616	5.06e-280	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DOALAIPI_01617	5.12e-266	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DOALAIPI_01618	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DOALAIPI_01619	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
DOALAIPI_01620	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
DOALAIPI_01621	1.02e-187	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
DOALAIPI_01622	2.1e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DOALAIPI_01623	7.06e-79	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
DOALAIPI_01624	7.1e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DOALAIPI_01625	3.39e-230	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
DOALAIPI_01626	9.91e-217	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DOALAIPI_01627	4.3e-113	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
DOALAIPI_01628	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
DOALAIPI_01629	1.46e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
DOALAIPI_01630	7.52e-238	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DOALAIPI_01631	2.73e-91	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
DOALAIPI_01632	1e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
DOALAIPI_01633	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
DOALAIPI_01634	4.45e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DOALAIPI_01635	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
DOALAIPI_01636	4.94e-210	-	-	-	G	-	-	-	Phosphotransferase enzyme family
DOALAIPI_01637	1.88e-101	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DOALAIPI_01638	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DOALAIPI_01639	5.61e-71	-	-	-	-	-	-	-	-
DOALAIPI_01640	1.86e-162	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DOALAIPI_01641	8.38e-232	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
DOALAIPI_01642	2.76e-76	-	-	-	-	-	-	-	-
DOALAIPI_01643	3.37e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
DOALAIPI_01644	4.3e-256	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
DOALAIPI_01645	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DOALAIPI_01646	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DOALAIPI_01647	3.81e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DOALAIPI_01648	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
DOALAIPI_01649	8.1e-118	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DOALAIPI_01650	1.87e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DOALAIPI_01651	3.09e-85	-	-	-	-	-	-	-	-
DOALAIPI_01652	1.22e-222	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
DOALAIPI_01653	1.16e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DOALAIPI_01654	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DOALAIPI_01655	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DOALAIPI_01656	1.96e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
DOALAIPI_01657	1.2e-59	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
DOALAIPI_01658	1.38e-273	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
DOALAIPI_01659	5.44e-109	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
DOALAIPI_01660	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DOALAIPI_01661	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DOALAIPI_01662	9.45e-298	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
DOALAIPI_01663	8.28e-178	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
DOALAIPI_01664	3.03e-179	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DOALAIPI_01665	1.72e-122	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DOALAIPI_01666	1.81e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
DOALAIPI_01667	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DOALAIPI_01668	3.54e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
DOALAIPI_01669	5.66e-231	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOALAIPI_01670	6.79e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
DOALAIPI_01671	1.19e-181	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
DOALAIPI_01672	3.72e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
DOALAIPI_01673	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
DOALAIPI_01674	1.29e-45	ynzC	-	-	S	-	-	-	UPF0291 protein
DOALAIPI_01675	2.52e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DOALAIPI_01676	4.77e-269	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
DOALAIPI_01677	5.93e-163	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DOALAIPI_01680	3.32e-19	-	-	-	-	-	-	-	-
DOALAIPI_01681	1.3e-14	-	-	-	-	-	-	-	-
DOALAIPI_01684	1.63e-16	-	-	-	-	-	-	-	-
DOALAIPI_01685	7.67e-14	-	-	-	-	-	-	-	-
DOALAIPI_01686	4.11e-16	-	-	-	-	-	-	-	-
DOALAIPI_01689	3.31e-20	-	-	-	-	-	-	-	-
DOALAIPI_01690	1.35e-198	-	-	-	M	-	-	-	MucBP domain
DOALAIPI_01691	1.87e-123	-	-	-	-	-	-	-	-
DOALAIPI_01692	1.25e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DOALAIPI_01693	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
DOALAIPI_01694	3.87e-200	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
DOALAIPI_01695	2.39e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DOALAIPI_01696	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DOALAIPI_01697	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DOALAIPI_01698	2.44e-20	-	-	-	-	-	-	-	-
DOALAIPI_01699	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
DOALAIPI_01700	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
DOALAIPI_01701	2.06e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DOALAIPI_01702	2.26e-302	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DOALAIPI_01703	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DOALAIPI_01704	1.2e-206	-	-	-	S	-	-	-	Tetratricopeptide repeat
DOALAIPI_01705	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DOALAIPI_01706	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DOALAIPI_01707	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
DOALAIPI_01708	1.2e-88	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
DOALAIPI_01709	2.19e-43	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
DOALAIPI_01711	2.09e-39	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DOALAIPI_01712	4.29e-42	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DOALAIPI_01724	6.62e-137	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DOALAIPI_01725	2.26e-56	-	-	-	-	-	-	-	-
DOALAIPI_01726	5.79e-72	-	-	-	T	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
DOALAIPI_01727	1.95e-37	-	-	-	-	-	-	-	-
DOALAIPI_01730	2.52e-18	-	-	-	K	-	-	-	sequence-specific DNA binding
DOALAIPI_01731	7.06e-06	-	-	-	K	-	-	-	Helix-turn-helix domain
DOALAIPI_01736	2.14e-31	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
DOALAIPI_01738	2.61e-19	-	-	-	S	ko:K09946	-	ko00000	Domain of unknown function (DUF1508)
DOALAIPI_01742	5.88e-146	-	-	-	S	-	-	-	AAA domain
DOALAIPI_01743	2.27e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
DOALAIPI_01744	1.01e-80	-	-	-	S	-	-	-	Putative HNHc nuclease
DOALAIPI_01745	7.04e-19	-	-	-	L	-	-	-	DnaD domain protein
DOALAIPI_01746	2.76e-71	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
DOALAIPI_01750	4.02e-65	-	-	-	S	-	-	-	ORF6C domain
DOALAIPI_01752	2.14e-19	-	-	-	-	-	-	-	-
DOALAIPI_01754	4.34e-107	-	-	-	Q	-	-	-	DNA (cytosine-5-)-methyltransferase activity
DOALAIPI_01759	3e-24	-	-	-	-	-	-	-	-
DOALAIPI_01767	2.9e-24	-	-	-	-	-	-	-	-
DOALAIPI_01769	2.19e-77	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
DOALAIPI_01770	1.56e-221	-	-	-	S	-	-	-	Terminase-like family
DOALAIPI_01771	1.32e-226	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
DOALAIPI_01772	2.3e-107	-	-	-	S	-	-	-	Phage Mu protein F like protein
DOALAIPI_01774	1.16e-108	gpG	-	-	-	-	-	-	-
DOALAIPI_01775	1.68e-52	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
DOALAIPI_01776	8.91e-55	-	-	-	-	-	-	-	-
DOALAIPI_01777	6.27e-65	-	-	-	-	-	-	-	-
DOALAIPI_01778	9.74e-45	-	-	-	-	-	-	-	-
DOALAIPI_01779	1.48e-99	-	-	-	-	-	-	-	-
DOALAIPI_01782	0.0	-	-	-	D	-	-	-	domain protein
DOALAIPI_01783	1.92e-193	-	-	-	S	-	-	-	Phage tail protein
DOALAIPI_01784	0.0	-	-	-	S	-	-	-	Peptidase family M23
DOALAIPI_01785	1.22e-06	-	-	-	O	-	-	-	gp58-like protein
DOALAIPI_01789	7.02e-84	-	-	-	-	-	-	-	-
DOALAIPI_01792	5.83e-49	-	-	-	-	-	-	-	-
DOALAIPI_01793	1.72e-73	-	-	-	S	-	-	-	COG5546 Small integral membrane protein
DOALAIPI_01794	2.41e-125	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
DOALAIPI_01795	8.95e-273	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DOALAIPI_01796	4.85e-25	-	-	-	-	-	-	-	-
DOALAIPI_01797	1.64e-35	-	-	-	S	-	-	-	Bacterial PH domain
DOALAIPI_01798	3.22e-22	-	-	-	E	-	-	-	Zn peptidase
DOALAIPI_01799	4.77e-20	-	-	-	K	-	-	-	Helix-turn-helix
DOALAIPI_01800	5.85e-09	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DOALAIPI_01801	4.11e-49	-	-	-	-	-	-	-	-
DOALAIPI_01804	2.97e-41	-	-	-	-	-	-	-	-
DOALAIPI_01806	8.3e-105	-	-	-	S	-	-	-	Siphovirus Gp157
DOALAIPI_01807	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
DOALAIPI_01808	1.5e-181	-	-	-	L	-	-	-	AAA domain
DOALAIPI_01809	6.7e-119	-	-	-	-	-	-	-	-
DOALAIPI_01810	2.47e-180	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
DOALAIPI_01811	5.7e-299	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
DOALAIPI_01814	2.13e-77	-	-	-	S	-	-	-	VRR_NUC
DOALAIPI_01816	1.46e-27	-	-	-	-	-	-	-	-
DOALAIPI_01819	1.04e-53	-	-	-	-	-	-	-	-
DOALAIPI_01822	2.83e-104	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
DOALAIPI_01824	8.89e-86	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
DOALAIPI_01825	1.43e-275	yqaT	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
DOALAIPI_01826	3.16e-261	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
DOALAIPI_01827	1.49e-176	-	-	-	S	-	-	-	Phage Mu protein F like protein
DOALAIPI_01829	2.47e-42	-	-	-	S	-	-	-	YjcQ protein
DOALAIPI_01830	1.81e-89	-	-	-	S	-	-	-	aminoacyl-tRNA ligase activity
DOALAIPI_01831	2.57e-159	-	-	-	-	-	-	-	-
DOALAIPI_01832	5.28e-62	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
DOALAIPI_01833	3.45e-07	-	-	-	-	-	-	-	-
DOALAIPI_01834	3.11e-58	-	-	-	S	-	-	-	exonuclease activity
DOALAIPI_01835	5.12e-56	-	-	-	-	-	-	-	-
DOALAIPI_01836	3.82e-110	-	-	-	S	-	-	-	Phage major tail protein 2
DOALAIPI_01837	2.04e-59	-	-	-	S	-	-	-	Pfam:Phage_TAC_12
DOALAIPI_01839	1.67e-222	-	-	-	S	-	-	-	peptidoglycan catabolic process
DOALAIPI_01841	6.45e-241	-	-	-	S	-	-	-	peptidoglycan catabolic process
DOALAIPI_01844	2.78e-98	-	-	-	S	-	-	-	Bacteriophage holin family
DOALAIPI_01845	4.79e-118	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
DOALAIPI_01846	8.95e-273	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DOALAIPI_01847	4.85e-25	-	-	-	-	-	-	-	-
DOALAIPI_01848	1.64e-35	-	-	-	S	-	-	-	Bacterial PH domain
DOALAIPI_01849	3.22e-22	-	-	-	E	-	-	-	Zn peptidase
DOALAIPI_01850	4.77e-20	-	-	-	K	-	-	-	Helix-turn-helix
DOALAIPI_01851	5.85e-09	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DOALAIPI_01852	4.11e-49	-	-	-	-	-	-	-	-
DOALAIPI_01855	2.97e-41	-	-	-	-	-	-	-	-
DOALAIPI_01857	8.3e-105	-	-	-	S	-	-	-	Siphovirus Gp157
DOALAIPI_01858	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
DOALAIPI_01859	1.5e-181	-	-	-	L	-	-	-	AAA domain
DOALAIPI_01860	6.7e-119	-	-	-	-	-	-	-	-
DOALAIPI_01861	2.47e-180	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
DOALAIPI_01862	5.7e-299	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
DOALAIPI_01865	2.13e-77	-	-	-	S	-	-	-	VRR_NUC
DOALAIPI_01867	1.46e-27	-	-	-	-	-	-	-	-
DOALAIPI_01870	1.04e-53	-	-	-	-	-	-	-	-
DOALAIPI_01873	2.83e-104	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
DOALAIPI_01875	8.89e-86	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
DOALAIPI_01876	1.43e-275	yqaT	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
DOALAIPI_01877	3.16e-261	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
DOALAIPI_01878	1.49e-176	-	-	-	S	-	-	-	Phage Mu protein F like protein
DOALAIPI_01880	2.47e-42	-	-	-	S	-	-	-	YjcQ protein
DOALAIPI_01881	1.81e-89	-	-	-	S	-	-	-	aminoacyl-tRNA ligase activity
DOALAIPI_01882	2.57e-159	-	-	-	-	-	-	-	-
DOALAIPI_01883	5.28e-62	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
DOALAIPI_01884	3.45e-07	-	-	-	-	-	-	-	-
DOALAIPI_01885	3.11e-58	-	-	-	S	-	-	-	exonuclease activity
DOALAIPI_01886	5.12e-56	-	-	-	-	-	-	-	-
DOALAIPI_01887	3.82e-110	-	-	-	S	-	-	-	Phage major tail protein 2
DOALAIPI_01888	2.04e-59	-	-	-	S	-	-	-	Pfam:Phage_TAC_12
DOALAIPI_01890	1.67e-222	-	-	-	S	-	-	-	peptidoglycan catabolic process
DOALAIPI_01892	6.45e-241	-	-	-	S	-	-	-	peptidoglycan catabolic process
DOALAIPI_01895	2.78e-98	-	-	-	S	-	-	-	Bacteriophage holin family
DOALAIPI_01896	4.79e-118	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
DOALAIPI_01897	3.08e-204	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DOALAIPI_01899	6.28e-76	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
DOALAIPI_01900	3.46e-76	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
DOALAIPI_01901	4.7e-56	-	-	-	-	-	-	-	-
DOALAIPI_01902	7.9e-165	-	-	-	-	-	-	-	-
DOALAIPI_01903	2.22e-64	-	-	-	-	-	-	-	-
DOALAIPI_01904	4.73e-17	-	-	-	-	-	-	-	-
DOALAIPI_01909	1.61e-125	xtmA	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
DOALAIPI_01910	2.37e-167	-	-	-	L	ko:K06909	-	ko00000	Phage terminase, large subunit
DOALAIPI_01911	2.66e-155	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
DOALAIPI_01912	1.29e-112	-	-	-	S	-	-	-	Phage minor capsid protein 2
DOALAIPI_01914	1.3e-26	-	-	-	S	-	-	-	Phage minor structural protein GP20
DOALAIPI_01915	1.44e-120	-	-	-	-	-	-	-	-
DOALAIPI_01917	3.32e-38	-	-	-	S	-	-	-	Minor capsid protein
DOALAIPI_01919	2.1e-16	-	-	-	S	-	-	-	Minor capsid protein from bacteriophage
DOALAIPI_01920	1.67e-52	-	-	-	N	-	-	-	domain, Protein
DOALAIPI_01922	3.69e-35	-	-	-	S	-	-	-	Bacteriophage Gp15 protein
DOALAIPI_01923	8.6e-132	-	-	-	S	-	-	-	peptidoglycan catabolic process
DOALAIPI_01925	1.54e-68	-	-	-	M	-	-	-	Prophage endopeptidase tail
DOALAIPI_01928	4.21e-49	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
DOALAIPI_01930	1.83e-44	-	-	-	-	-	-	-	-
DOALAIPI_01931	6.52e-33	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
DOALAIPI_01932	2.27e-115	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
DOALAIPI_01934	9.15e-131	-	-	-	-	-	-	-	-
DOALAIPI_01935	0.0	-	-	-	M	-	-	-	domain protein
DOALAIPI_01936	9.26e-77	-	-	-	-	-	-	-	-
DOALAIPI_01937	2.72e-238	ampC	-	-	V	-	-	-	Beta-lactamase
DOALAIPI_01938	1.78e-304	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
DOALAIPI_01939	6.17e-104	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
DOALAIPI_01940	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
DOALAIPI_01941	5.64e-297	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
DOALAIPI_01942	3.43e-173	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
DOALAIPI_01943	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
DOALAIPI_01944	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
DOALAIPI_01945	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DOALAIPI_01946	3.9e-210	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DOALAIPI_01947	1.09e-250	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DOALAIPI_01948	1.49e-292	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DOALAIPI_01949	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DOALAIPI_01950	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DOALAIPI_01951	1.65e-246	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
DOALAIPI_01952	7.81e-165	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
DOALAIPI_01953	5.4e-292	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
DOALAIPI_01954	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
DOALAIPI_01955	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DOALAIPI_01956	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DOALAIPI_01957	6.84e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DOALAIPI_01958	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DOALAIPI_01959	3.72e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DOALAIPI_01960	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DOALAIPI_01961	8.95e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
DOALAIPI_01962	5.05e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
DOALAIPI_01963	4.45e-310	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DOALAIPI_01964	1.05e-226	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
DOALAIPI_01965	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
DOALAIPI_01966	9.49e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
DOALAIPI_01967	1.21e-63	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
DOALAIPI_01968	6.32e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
DOALAIPI_01969	1.49e-190	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DOALAIPI_01970	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
DOALAIPI_01971	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
DOALAIPI_01972	1.91e-178	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
DOALAIPI_01973	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
DOALAIPI_01974	5.75e-122	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
DOALAIPI_01975	2.42e-200	yvgN	-	-	S	-	-	-	Aldo keto reductase
DOALAIPI_01976	1.4e-260	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
DOALAIPI_01977	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
DOALAIPI_01978	3.61e-61	-	-	-	-	-	-	-	-
DOALAIPI_01979	7.66e-309	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
DOALAIPI_01980	1.01e-111	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
DOALAIPI_01981	9.79e-29	-	-	-	-	-	-	-	-
DOALAIPI_01982	1.16e-97	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
DOALAIPI_01983	2.41e-179	-	-	-	S	-	-	-	Membrane
DOALAIPI_01984	1.39e-179	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
DOALAIPI_01985	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
DOALAIPI_01986	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
DOALAIPI_01987	9.82e-298	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
DOALAIPI_01988	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
DOALAIPI_01989	0.0	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
DOALAIPI_01990	7.61e-217	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
DOALAIPI_01991	0.0	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
DOALAIPI_01992	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DOALAIPI_01993	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DOALAIPI_01994	3.37e-272	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
DOALAIPI_01995	1.67e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DOALAIPI_01996	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DOALAIPI_01997	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
DOALAIPI_01998	1.15e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
DOALAIPI_01999	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
DOALAIPI_02000	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DOALAIPI_02001	8.62e-293	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
DOALAIPI_02004	1.82e-21	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
DOALAIPI_02005	6.35e-69	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
DOALAIPI_02006	4.38e-242	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
DOALAIPI_02007	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
DOALAIPI_02008	8.16e-206	-	-	-	-	-	-	-	-
DOALAIPI_02009	1.06e-19	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
DOALAIPI_02010	7.42e-95	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
DOALAIPI_02011	3.81e-48	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
DOALAIPI_02012	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
DOALAIPI_02013	1.6e-269	-	-	-	EGP	-	-	-	Major Facilitator
DOALAIPI_02014	4.56e-175	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
DOALAIPI_02015	5.75e-152	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
DOALAIPI_02016	3.18e-11	-	-	-	-	-	-	-	-
DOALAIPI_02017	6.57e-79	-	-	-	-	-	-	-	-
DOALAIPI_02018	1e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
DOALAIPI_02019	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
DOALAIPI_02020	0.0	fusA1	-	-	J	-	-	-	elongation factor G
DOALAIPI_02021	1.08e-213	-	-	-	GK	-	-	-	ROK family
DOALAIPI_02022	2.79e-310	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
DOALAIPI_02023	1.58e-73	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
DOALAIPI_02024	3.37e-307	-	-	-	E	-	-	-	amino acid
DOALAIPI_02025	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
DOALAIPI_02026	1.23e-170	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
DOALAIPI_02027	1.65e-113	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DOALAIPI_02028	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DOALAIPI_02029	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
DOALAIPI_02030	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
DOALAIPI_02031	2.34e-241	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOALAIPI_02032	1.68e-115	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
DOALAIPI_02033	2.94e-80	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
DOALAIPI_02034	3.77e-246	cobT	2.4.2.21	-	F	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
DOALAIPI_02035	3.41e-169	-	-	-	H	-	-	-	Uroporphyrinogen-III synthase
DOALAIPI_02036	3.23e-145	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
DOALAIPI_02037	5.84e-174	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DOALAIPI_02038	1.71e-131	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobinamide kinase / cobinamide phosphate guanyltransferase
DOALAIPI_02039	0.0	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
DOALAIPI_02040	6.35e-229	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
DOALAIPI_02041	1.78e-210	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
DOALAIPI_02042	3.96e-293	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DOALAIPI_02043	1.11e-101	cysG	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Putative NAD(P)-binding
DOALAIPI_02044	0.0	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
DOALAIPI_02045	4.15e-190	cbiO	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	part of an ABC transporter complex. Responsible for energy coupling to the transport system
DOALAIPI_02046	1.43e-151	cbiQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
DOALAIPI_02047	2.56e-70	cbiN	-	-	P	ko:K02009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
DOALAIPI_02048	8.97e-171	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
DOALAIPI_02049	6.04e-159	cbiL	2.1.1.130, 2.1.1.151	-	H	ko:K03394	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
DOALAIPI_02050	2.92e-186	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalt chelatase (CbiK)
DOALAIPI_02051	0.0	cobA	2.1.1.107, 4.2.1.75	-	H	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
DOALAIPI_02052	1.22e-170	cobK	1.3.1.106, 1.3.1.54	-	H	ko:K05895	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-6x reductase CbiJ/CobK
DOALAIPI_02053	3.53e-169	cbiH	2.1.1.131	-	H	ko:K05934	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
DOALAIPI_02054	8.21e-246	cbiG	3.7.1.12	-	H	ko:K02189	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin synthesis G C-terminus
DOALAIPI_02055	2.77e-172	cbiF	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
DOALAIPI_02056	2.89e-124	cbiT	2.1.1.196	-	H	ko:K02191	ko00860,map00860	ko00000,ko00001,ko01000	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
DOALAIPI_02057	2.01e-141	cbiE	2.1.1.289	-	H	ko:K03399	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
DOALAIPI_02058	2.57e-272	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DOALAIPI_02059	6.88e-160	cbiC	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-8X methylmutase
DOALAIPI_02060	3.27e-229	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DOALAIPI_02061	0.0	cbiA	6.3.5.11, 6.3.5.9	-	F	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
DOALAIPI_02062	7.26e-266	cobD	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Aminotransferase class I and II
DOALAIPI_02063	7.96e-133	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
DOALAIPI_02064	4.68e-198	nqo1	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
DOALAIPI_02065	2.54e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
DOALAIPI_02066	2.69e-95	eutP	-	-	E	ko:K04029	-	ko00000	Ethanolamine utilisation - propanediol utilisation
DOALAIPI_02067	1.86e-116	-	-	-	P	-	-	-	Cadmium resistance transporter
DOALAIPI_02068	6.68e-156	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
DOALAIPI_02069	2.32e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Pfam:Y_phosphatase3C
DOALAIPI_02070	3.32e-74	-	-	-	E	ko:K04031	-	ko00000	BMC
DOALAIPI_02071	1.07e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DOALAIPI_02072	6.52e-270	pduQ	-	-	C	ko:K13921	ko00640,map00640	ko00000,ko00001	Iron-containing alcohol dehydrogenase
DOALAIPI_02073	0.0	pduP	1.2.1.87	-	C	ko:K13922	ko00640,map00640	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
DOALAIPI_02074	1.01e-104	pduO	-	-	S	-	-	-	Haem-degrading
DOALAIPI_02075	1.26e-137	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
DOALAIPI_02076	1.96e-55	pduN	-	-	CQ	ko:K04028	-	ko00000	Ethanolamine utilisation protein EutN/carboxysome
DOALAIPI_02077	2.75e-116	-	-	-	S	-	-	-	Putative propanediol utilisation
DOALAIPI_02078	1.77e-151	pduL	2.3.1.222	-	Q	ko:K13923	ko00640,map00640	ko00000,ko00001,ko01000	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
DOALAIPI_02079	1.18e-56	pduA_2	-	-	CQ	ko:K04027	-	ko00000	BMC
DOALAIPI_02080	2.31e-112	-	-	-	CQ	-	-	-	BMC
DOALAIPI_02081	8.32e-79	pduH	-	-	S	-	-	-	Dehydratase medium subunit
DOALAIPI_02082	0.0	pduG	-	-	D	-	-	-	Diol dehydratase reactivase ATPase-like domain
DOALAIPI_02083	2.8e-109	pduE	4.2.1.28	-	Q	ko:K13920	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase small subunit
DOALAIPI_02084	6.34e-165	pduD	4.2.1.28	-	Q	ko:K13919	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase medium subunit
DOALAIPI_02085	0.0	pduC	4.2.1.28	-	Q	ko:K01699	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase large subunit
DOALAIPI_02086	3.41e-170	pduB	-	-	E	-	-	-	BMC
DOALAIPI_02087	2.72e-56	-	-	-	CQ	-	-	-	BMC
DOALAIPI_02088	1.1e-254	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
DOALAIPI_02089	2.21e-190	eutJ	-	-	E	ko:K04024	-	ko00000	Hsp70 protein
DOALAIPI_02090	1.98e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
DOALAIPI_02091	1.2e-207	-	-	-	-	-	-	-	-
DOALAIPI_02092	2.62e-200	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
DOALAIPI_02093	1.68e-239	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
DOALAIPI_02094	6.1e-170	XK27_07210	-	-	S	-	-	-	B3 4 domain
DOALAIPI_02095	4.73e-102	yybA	-	-	K	-	-	-	Transcriptional regulator
DOALAIPI_02096	5.25e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
DOALAIPI_02097	9.82e-118	-	-	-	GM	-	-	-	epimerase
DOALAIPI_02098	1.63e-197	-	-	-	V	-	-	-	(ABC) transporter
DOALAIPI_02099	5e-309	yhdP	-	-	S	-	-	-	Transporter associated domain
DOALAIPI_02100	4e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
DOALAIPI_02101	3.68e-97	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
DOALAIPI_02102	4.37e-245	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
DOALAIPI_02103	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DOALAIPI_02104	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DOALAIPI_02105	1.8e-45	-	-	-	-	-	-	-	-
DOALAIPI_02106	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
DOALAIPI_02107	3.96e-76	-	-	-	-	-	-	-	-
DOALAIPI_02108	2.09e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DOALAIPI_02109	4.07e-85	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
DOALAIPI_02110	1.61e-81	-	-	-	S	-	-	-	macrophage migration inhibitory factor
DOALAIPI_02111	2.63e-214	-	-	-	C	-	-	-	Oxidoreductase
DOALAIPI_02114	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
DOALAIPI_02115	1.32e-112	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
DOALAIPI_02116	1.28e-62	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
DOALAIPI_02119	3.98e-146	-	-	-	-	-	-	-	-
DOALAIPI_02120	0.0	-	-	-	EGP	-	-	-	Major Facilitator
DOALAIPI_02121	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
DOALAIPI_02122	3.15e-171	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
DOALAIPI_02123	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
DOALAIPI_02124	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DOALAIPI_02125	1.58e-198	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
DOALAIPI_02126	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
DOALAIPI_02127	1.16e-111	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
DOALAIPI_02129	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
DOALAIPI_02130	1.29e-235	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
DOALAIPI_02131	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
DOALAIPI_02132	1.76e-171	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DOALAIPI_02133	1.54e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DOALAIPI_02134	2.89e-272	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
DOALAIPI_02135	3.36e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DOALAIPI_02136	1.32e-168	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DOALAIPI_02137	1.23e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
DOALAIPI_02138	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
DOALAIPI_02139	2.4e-160	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DOALAIPI_02140	1.93e-65	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
DOALAIPI_02141	1.69e-129	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
DOALAIPI_02142	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DOALAIPI_02143	5.99e-266	yacL	-	-	S	-	-	-	domain protein
DOALAIPI_02144	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
DOALAIPI_02145	2.52e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DOALAIPI_02146	6.35e-176	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DOALAIPI_02147	7.11e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DOALAIPI_02148	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
DOALAIPI_02149	8.03e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DOALAIPI_02150	2.38e-157	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DOALAIPI_02152	5.97e-285	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
DOALAIPI_02154	1.44e-315	-	-	-	M	-	-	-	Glycosyl transferase family group 2
DOALAIPI_02155	4.92e-265	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
DOALAIPI_02156	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DOALAIPI_02157	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DOALAIPI_02158	2.91e-65	-	-	-	-	-	-	-	-
DOALAIPI_02160	4.34e-63	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DOALAIPI_02161	9.71e-76	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
DOALAIPI_02162	1.39e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
DOALAIPI_02163	3.67e-176	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
DOALAIPI_02164	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
DOALAIPI_02165	3.81e-254	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DOALAIPI_02166	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DOALAIPI_02167	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
DOALAIPI_02168	6.21e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DOALAIPI_02169	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DOALAIPI_02170	6.86e-61	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DOALAIPI_02171	2.01e-141	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DOALAIPI_02172	2.23e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
DOALAIPI_02173	1.57e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DOALAIPI_02174	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
DOALAIPI_02175	1.24e-233	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
DOALAIPI_02176	1.51e-75	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
DOALAIPI_02177	3.17e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DOALAIPI_02178	2.12e-176	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
DOALAIPI_02179	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
DOALAIPI_02180	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DOALAIPI_02181	6.8e-224	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
DOALAIPI_02182	1.48e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
DOALAIPI_02183	7.34e-162	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
DOALAIPI_02184	4.12e-133	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
DOALAIPI_02185	5.83e-251	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DOALAIPI_02186	1.26e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DOALAIPI_02187	2.02e-287	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DOALAIPI_02188	3.64e-177	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DOALAIPI_02189	6.08e-180	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
DOALAIPI_02190	4.39e-289	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DOALAIPI_02191	2.41e-232	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DOALAIPI_02192	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
DOALAIPI_02193	4.67e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DOALAIPI_02195	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DOALAIPI_02196	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DOALAIPI_02197	4.47e-44	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	YbaK proline--tRNA ligase associated domain protein
DOALAIPI_02198	7.42e-44	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
DOALAIPI_02199	0.0	-	-	-	E	-	-	-	amino acid
DOALAIPI_02200	0.0	ydaO	-	-	E	-	-	-	amino acid
DOALAIPI_02201	1.78e-51	-	-	-	-	-	-	-	-
DOALAIPI_02202	7.25e-88	-	-	-	K	-	-	-	Transcriptional regulator
DOALAIPI_02203	8.88e-196	-	-	-	EGP	-	-	-	Major Facilitator
DOALAIPI_02204	3.97e-37	-	-	-	EGP	-	-	-	Major Facilitator
DOALAIPI_02205	1.63e-145	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
DOALAIPI_02206	1.83e-124	-	-	-	S	-	-	-	reductase
DOALAIPI_02207	6.23e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
DOALAIPI_02208	4.87e-189	-	-	-	E	-	-	-	Glyoxalase-like domain
DOALAIPI_02209	1.22e-156	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DOALAIPI_02210	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
DOALAIPI_02211	9.6e-199	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOALAIPI_02212	1.14e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
DOALAIPI_02213	1.08e-269	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
DOALAIPI_02215	4.65e-68	-	-	-	-	-	-	-	-
DOALAIPI_02216	4.45e-65	p75	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
DOALAIPI_02217	4.09e-294	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
DOALAIPI_02220	1.85e-301	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
DOALAIPI_02221	9.01e-179	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
DOALAIPI_02223	8.94e-313	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
DOALAIPI_02225	9.74e-98	-	-	-	O	-	-	-	OsmC-like protein
DOALAIPI_02226	7.97e-227	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOALAIPI_02227	1.61e-272	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DOALAIPI_02228	8.68e-44	-	-	-	-	-	-	-	-
DOALAIPI_02229	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
DOALAIPI_02230	1.03e-208	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
DOALAIPI_02232	8.86e-133	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
DOALAIPI_02233	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOALAIPI_02234	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
DOALAIPI_02235	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
DOALAIPI_02236	4.97e-220	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
DOALAIPI_02237	3.58e-263	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
DOALAIPI_02238	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
DOALAIPI_02239	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
DOALAIPI_02240	8.72e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
DOALAIPI_02241	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
DOALAIPI_02242	3.7e-176	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
DOALAIPI_02243	4.24e-214	-	-	-	C	-	-	-	Aldo keto reductase
DOALAIPI_02244	1.86e-63	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
DOALAIPI_02245	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
DOALAIPI_02246	3.77e-113	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
DOALAIPI_02247	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
DOALAIPI_02248	7.16e-231	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DOALAIPI_02249	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DOALAIPI_02250	5.15e-128	-	-	-	-	-	-	-	-
DOALAIPI_02251	2.69e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DOALAIPI_02253	8.62e-116	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
DOALAIPI_02254	6.4e-314	-	-	-	E	-	-	-	amino acid
DOALAIPI_02255	8.03e-143	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
DOALAIPI_02256	4.06e-93	-	-	-	-	-	-	-	-
DOALAIPI_02257	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
DOALAIPI_02258	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
DOALAIPI_02259	0.0	sdrF	-	-	M	ko:K14194	ko05150,map05150	ko00000,ko00001	protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
DOALAIPI_02260	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
DOALAIPI_02261	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
DOALAIPI_02262	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
DOALAIPI_02263	6.91e-235	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
DOALAIPI_02264	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DOALAIPI_02265	4.41e-131	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
DOALAIPI_02266	2.29e-262	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
DOALAIPI_02267	5.37e-220	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein