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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IOFPBDMD_00001	0.0	bglB	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
IOFPBDMD_00003	3.73e-214	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
IOFPBDMD_00004	3.27e-213	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter
IOFPBDMD_00005	1.68e-208	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IOFPBDMD_00006	4.78e-180	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_00007	2.27e-220	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
IOFPBDMD_00008	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
IOFPBDMD_00009	8.07e-233	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
IOFPBDMD_00010	0.0	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
IOFPBDMD_00011	2.64e-94	-	-	-	S	-	-	-	GtrA-like protein
IOFPBDMD_00012	1.59e-14	-	-	-	-	-	-	-	-
IOFPBDMD_00013	3.17e-11	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOFPBDMD_00014	6.13e-165	ciaR	-	-	K	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
IOFPBDMD_00015	1.87e-307	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
IOFPBDMD_00016	1.99e-87	-	-	-	S	-	-	-	Belongs to the HesB IscA family
IOFPBDMD_00017	1.19e-156	ydgI	-	-	C	-	-	-	Nitroreductase family
IOFPBDMD_00018	7.2e-260	lldD	1.13.12.4	-	C	ko:K00467	ko00620,map00620	ko00000,ko00001,ko01000	IMP dehydrogenase / GMP reductase domain
IOFPBDMD_00021	1.29e-07	rggD	-	-	K	-	-	-	Transcriptional regulator RggD
IOFPBDMD_00025	7.15e-232	-	-	-	K	-	-	-	sequence-specific DNA binding
IOFPBDMD_00026	6.52e-75	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
IOFPBDMD_00027	5.89e-66	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
IOFPBDMD_00028	1.71e-64	-	-	-	-	-	-	-	-
IOFPBDMD_00029	7.49e-237	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
IOFPBDMD_00030	5.83e-75	-	-	-	-	-	-	-	-
IOFPBDMD_00031	6.82e-104	-	-	-	-	-	-	-	-
IOFPBDMD_00032	5.52e-265	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
IOFPBDMD_00033	1.99e-36	-	-	-	-	-	-	-	-
IOFPBDMD_00034	1e-129	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IOFPBDMD_00035	6.06e-97	-	-	-	-	-	-	-	-
IOFPBDMD_00036	3.6e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
IOFPBDMD_00037	9.06e-136	-	-	-	S	-	-	-	Flavin reductase like domain
IOFPBDMD_00038	8.46e-177	-	-	-	-	-	-	-	-
IOFPBDMD_00039	1e-136	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IOFPBDMD_00040	2.41e-81	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
IOFPBDMD_00041	8.59e-221	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
IOFPBDMD_00042	6.96e-206	mleR	-	-	K	-	-	-	LysR family
IOFPBDMD_00043	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
IOFPBDMD_00044	8.81e-218	mleP	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
IOFPBDMD_00045	1.6e-114	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IOFPBDMD_00046	2.95e-123	-	-	-	-	-	-	-	-
IOFPBDMD_00047	6.46e-218	-	-	-	K	-	-	-	sequence-specific DNA binding
IOFPBDMD_00048	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
IOFPBDMD_00049	0.0	pepF	-	-	E	-	-	-	Oligopeptidase F
IOFPBDMD_00050	2.01e-102	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
IOFPBDMD_00051	1.05e-71	-	-	-	-	-	-	-	-
IOFPBDMD_00052	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
IOFPBDMD_00053	3.53e-227	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
IOFPBDMD_00054	1.03e-77	-	-	-	-	-	-	-	-
IOFPBDMD_00055	2.66e-119	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IOFPBDMD_00056	2.39e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IOFPBDMD_00057	5.26e-155	XK27_05175	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
IOFPBDMD_00058	6.42e-101	-	-	-	K	-	-	-	Transcriptional regulator
IOFPBDMD_00059	2.81e-230	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
IOFPBDMD_00060	2.14e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
IOFPBDMD_00061	1.3e-201	dkgB	-	-	S	-	-	-	reductase
IOFPBDMD_00062	1.84e-161	-	-	-	-	-	-	-	-
IOFPBDMD_00063	9.91e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
IOFPBDMD_00064	4.32e-148	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
IOFPBDMD_00065	5.25e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
IOFPBDMD_00066	3.84e-280	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
IOFPBDMD_00067	1.19e-112	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IOFPBDMD_00068	1.25e-134	yjbF	-	-	S	-	-	-	SNARE associated Golgi protein
IOFPBDMD_00069	2.42e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IOFPBDMD_00070	4.98e-250	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IOFPBDMD_00071	2.16e-264	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IOFPBDMD_00072	6.98e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IOFPBDMD_00073	2.9e-85	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
IOFPBDMD_00074	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
IOFPBDMD_00075	1.45e-150	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
IOFPBDMD_00076	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IOFPBDMD_00077	2.17e-265	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOFPBDMD_00078	1.54e-305	ytoI	-	-	K	-	-	-	DRTGG domain
IOFPBDMD_00079	3.53e-228	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
IOFPBDMD_00080	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IOFPBDMD_00081	4.08e-219	-	-	-	-	-	-	-	-
IOFPBDMD_00082	1.2e-07	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IOFPBDMD_00083	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IOFPBDMD_00084	9.14e-259	-	-	-	-	-	-	-	-
IOFPBDMD_00085	1.4e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
IOFPBDMD_00086	3.79e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IOFPBDMD_00087	1.85e-69	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
IOFPBDMD_00088	3.45e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IOFPBDMD_00089	7.74e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
IOFPBDMD_00090	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IOFPBDMD_00091	3.64e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IOFPBDMD_00092	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOFPBDMD_00093	1.46e-305	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
IOFPBDMD_00094	1.2e-49	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOFPBDMD_00095	5.21e-315	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IOFPBDMD_00096	1.18e-109	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
IOFPBDMD_00097	0.0	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IOFPBDMD_00098	2.24e-123	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
IOFPBDMD_00099	7.42e-172	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
IOFPBDMD_00100	3.12e-110	ykuL	-	-	S	-	-	-	CBS domain
IOFPBDMD_00101	1.97e-200	-	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
IOFPBDMD_00102	5.04e-200	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
IOFPBDMD_00104	7.19e-40	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IOFPBDMD_00105	8.13e-104	ytxH	-	-	S	-	-	-	YtxH-like protein
IOFPBDMD_00106	1.83e-119	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
IOFPBDMD_00107	2.2e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IOFPBDMD_00108	6.12e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
IOFPBDMD_00109	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
IOFPBDMD_00110	3.18e-07	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOFPBDMD_00111	1.24e-162	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
IOFPBDMD_00112	2.39e-173	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IOFPBDMD_00113	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
IOFPBDMD_00114	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
IOFPBDMD_00115	3.48e-73	-	-	-	-	-	-	-	-
IOFPBDMD_00116	2.32e-238	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
IOFPBDMD_00117	2.41e-153	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
IOFPBDMD_00118	1.94e-148	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IOFPBDMD_00119	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IOFPBDMD_00120	9.92e-143	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
IOFPBDMD_00121	4.68e-187	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IOFPBDMD_00122	8.78e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
IOFPBDMD_00123	4.31e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
IOFPBDMD_00124	6.48e-115	pgpA	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phosphatidylglycerophosphatase A
IOFPBDMD_00125	9.5e-238	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
IOFPBDMD_00126	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IOFPBDMD_00127	1.17e-82	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
IOFPBDMD_00128	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IOFPBDMD_00129	1.12e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IOFPBDMD_00130	4.9e-207	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IOFPBDMD_00131	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IOFPBDMD_00132	2.04e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
IOFPBDMD_00133	9.66e-308	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IOFPBDMD_00134	8.3e-105	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
IOFPBDMD_00135	1.87e-84	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
IOFPBDMD_00136	2.33e-52	yabO	-	-	J	-	-	-	S4 domain protein
IOFPBDMD_00137	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IOFPBDMD_00138	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IOFPBDMD_00139	1.05e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IOFPBDMD_00140	5.04e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IOFPBDMD_00141	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
IOFPBDMD_00142	2.6e-124	padR	-	-	K	-	-	-	Transcriptional regulator PadR-like family
IOFPBDMD_00143	0.0	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
IOFPBDMD_00144	3.35e-148	-	-	-	S	-	-	-	Flavodoxin-like fold
IOFPBDMD_00145	1.9e-154	-	-	-	S	-	-	-	(CBS) domain
IOFPBDMD_00146	1.69e-167	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
IOFPBDMD_00147	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
IOFPBDMD_00148	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
IOFPBDMD_00149	1.33e-111	queT	-	-	S	-	-	-	QueT transporter
IOFPBDMD_00151	2.32e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
IOFPBDMD_00152	5.46e-51	-	-	-	-	-	-	-	-
IOFPBDMD_00153	2.9e-276	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IOFPBDMD_00154	2.25e-83	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IOFPBDMD_00155	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IOFPBDMD_00156	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IOFPBDMD_00157	1.77e-189	-	-	-	-	-	-	-	-
IOFPBDMD_00158	1.11e-158	-	-	-	S	-	-	-	Tetratricopeptide repeat
IOFPBDMD_00159	4.49e-159	-	-	-	-	-	-	-	-
IOFPBDMD_00160	3.27e-96	-	-	-	-	-	-	-	-
IOFPBDMD_00161	3.24e-57	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
IOFPBDMD_00162	1.91e-299	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IOFPBDMD_00164	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IOFPBDMD_00165	2.23e-279	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IOFPBDMD_00168	4.99e-194	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
IOFPBDMD_00169	3.09e-103	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IOFPBDMD_00170	1.21e-103	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
IOFPBDMD_00171	6.94e-201	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
IOFPBDMD_00172	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
IOFPBDMD_00173	1.53e-107	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
IOFPBDMD_00174	3.18e-239	-	-	-	S	-	-	-	DUF218 domain
IOFPBDMD_00175	1.4e-78	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IOFPBDMD_00176	1.16e-95	-	-	-	-	-	-	-	-
IOFPBDMD_00177	6.37e-67	nudA	-	-	S	-	-	-	ASCH
IOFPBDMD_00178	2.2e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOFPBDMD_00179	3.01e-295	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IOFPBDMD_00180	1.84e-281	ysaA	-	-	V	-	-	-	RDD family
IOFPBDMD_00181	1.01e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
IOFPBDMD_00182	1.84e-154	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_00183	1.38e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
IOFPBDMD_00184	1.1e-199	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
IOFPBDMD_00185	8.83e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IOFPBDMD_00186	4.13e-51	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
IOFPBDMD_00187	8e-197	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IOFPBDMD_00188	5.35e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IOFPBDMD_00189	7.18e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
IOFPBDMD_00190	7.89e-105	manR	2.7.1.194, 2.7.1.200, 2.7.1.202	-	G	ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
IOFPBDMD_00191	4.53e-238	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
IOFPBDMD_00192	3e-221	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
IOFPBDMD_00193	1.23e-161	-	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IOFPBDMD_00194	3.2e-212	-	-	-	T	-	-	-	GHKL domain
IOFPBDMD_00195	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IOFPBDMD_00196	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IOFPBDMD_00197	3.93e-41	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
IOFPBDMD_00198	3.43e-85	-	-	-	-	-	-	-	-
IOFPBDMD_00199	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IOFPBDMD_00200	8.68e-220	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
IOFPBDMD_00201	7.33e-188	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
IOFPBDMD_00202	4.46e-118	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
IOFPBDMD_00203	1.8e-217	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
IOFPBDMD_00204	2.35e-139	yiiE	-	-	S	-	-	-	Protein of unknown function (DUF1211)
IOFPBDMD_00205	3.42e-166	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
IOFPBDMD_00207	6.25e-217	-	-	-	-	-	-	-	-
IOFPBDMD_00208	1.12e-125	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
IOFPBDMD_00209	3.78e-51	-	-	-	-	-	-	-	-
IOFPBDMD_00210	3.46e-219	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
IOFPBDMD_00211	1e-220	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
IOFPBDMD_00212	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IOFPBDMD_00213	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
IOFPBDMD_00214	4.79e-222	ydhF	-	-	S	-	-	-	Aldo keto reductase
IOFPBDMD_00215	2.94e-198	-	-	-	Q	-	-	-	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
IOFPBDMD_00216	6.53e-118	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
IOFPBDMD_00217	1.3e-302	dinF	-	-	V	-	-	-	MatE
IOFPBDMD_00218	6.41e-141	-	-	-	S	ko:K06872	-	ko00000	TPM domain
IOFPBDMD_00219	4.87e-134	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
IOFPBDMD_00220	6.02e-246	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IOFPBDMD_00221	8.37e-90	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOFPBDMD_00222	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
IOFPBDMD_00223	2.58e-226	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_00224	0.0	choS	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IOFPBDMD_00225	0.0	-	-	-	L	-	-	-	DNA helicase
IOFPBDMD_00226	4.46e-189	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
IOFPBDMD_00227	2.03e-225	ydiA	-	-	P	ko:K11041	ko05150,map05150	ko00000,ko00001,ko02042	Voltage-dependent anion channel
IOFPBDMD_00228	5.4e-175	yadH	-	-	V	ko:K01992,ko:K09694	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
IOFPBDMD_00229	1.22e-170	cylA	-	-	V	ko:K01990,ko:K09695,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOFPBDMD_00230	9.8e-167	ydfF	-	-	K	-	-	-	Transcriptional
IOFPBDMD_00231	6.32e-141	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IOFPBDMD_00233	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
IOFPBDMD_00234	1.13e-138	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IOFPBDMD_00235	4.69e-94	-	-	-	K	-	-	-	MarR family
IOFPBDMD_00236	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
IOFPBDMD_00237	9.22e-246	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
IOFPBDMD_00238	5.39e-183	-	-	-	S	-	-	-	hydrolase
IOFPBDMD_00239	3.33e-78	-	-	-	-	-	-	-	-
IOFPBDMD_00240	1.71e-17	-	-	-	-	-	-	-	-
IOFPBDMD_00241	2.65e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
IOFPBDMD_00242	3.55e-163	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
IOFPBDMD_00243	4.01e-194	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
IOFPBDMD_00244	1.38e-117	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOFPBDMD_00245	2.17e-213	-	-	-	K	-	-	-	LysR substrate binding domain
IOFPBDMD_00246	4.76e-288	-	-	-	EK	-	-	-	Aminotransferase, class I
IOFPBDMD_00248	3.7e-60	-	-	-	-	-	-	-	-
IOFPBDMD_00249	5.18e-75	-	-	-	-	-	-	-	-
IOFPBDMD_00250	3.1e-254	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IOFPBDMD_00251	5.11e-149	ydfK	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
IOFPBDMD_00252	4.31e-115	-	-	-	-	-	-	-	-
IOFPBDMD_00254	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOFPBDMD_00255	1.94e-216	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
IOFPBDMD_00256	2.02e-168	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IOFPBDMD_00257	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IOFPBDMD_00258	1.06e-166	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IOFPBDMD_00259	2.87e-106	-	-	-	S	-	-	-	NusG domain II
IOFPBDMD_00260	7.23e-128	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
IOFPBDMD_00261	9.42e-232	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IOFPBDMD_00262	9.18e-105	-	-	-	-	-	-	-	-
IOFPBDMD_00263	3.41e-187	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
IOFPBDMD_00264	5.81e-125	-	-	-	-	-	-	-	-
IOFPBDMD_00265	1.29e-202	-	-	-	-	-	-	-	-
IOFPBDMD_00266	3.67e-196	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOFPBDMD_00267	2.02e-273	-	-	-	-	-	-	-	-
IOFPBDMD_00268	4.05e-247	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
IOFPBDMD_00269	2.58e-155	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	Rossmann-like domain
IOFPBDMD_00270	3.64e-249	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
IOFPBDMD_00271	1.45e-126	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
IOFPBDMD_00272	2.6e-185	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOFPBDMD_00273	2.3e-96	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IOFPBDMD_00274	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IOFPBDMD_00275	4.31e-312	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
IOFPBDMD_00276	5.16e-127	-	-	-	-	-	-	-	-
IOFPBDMD_00278	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IOFPBDMD_00279	1.36e-179	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
IOFPBDMD_00280	4.58e-225	-	-	-	S	-	-	-	Membrane
IOFPBDMD_00281	3.54e-82	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
IOFPBDMD_00282	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
IOFPBDMD_00283	6.07e-292	inlJ	-	-	M	-	-	-	MucBP domain
IOFPBDMD_00284	6.42e-88	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IOFPBDMD_00285	9.79e-121	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_00286	1.12e-138	-	-	-	K	-	-	-	sequence-specific DNA binding
IOFPBDMD_00287	1.06e-258	yacL	-	-	S	-	-	-	domain protein
IOFPBDMD_00288	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IOFPBDMD_00289	4.49e-130	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTPase
IOFPBDMD_00290	2.37e-65	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
IOFPBDMD_00291	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
IOFPBDMD_00292	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IOFPBDMD_00293	1.42e-249	-	-	-	-	-	-	-	-
IOFPBDMD_00294	7.65e-272	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IOFPBDMD_00295	2.55e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOFPBDMD_00296	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
IOFPBDMD_00297	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
IOFPBDMD_00298	2.36e-119	ccpN	-	-	K	-	-	-	Domain in cystathionine beta-synthase and other proteins.
IOFPBDMD_00299	1.14e-156	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IOFPBDMD_00300	1.1e-256	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
IOFPBDMD_00301	5.45e-61	-	-	-	-	-	-	-	-
IOFPBDMD_00302	2.43e-264	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
IOFPBDMD_00303	9.49e-26	-	-	-	S	-	-	-	CsbD-like
IOFPBDMD_00304	9.56e-189	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IOFPBDMD_00305	3.49e-242	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
IOFPBDMD_00306	4.06e-146	udp	2.4.2.3	-	F	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphorylase superfamily
IOFPBDMD_00307	3.92e-218	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
IOFPBDMD_00308	9.32e-118	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
IOFPBDMD_00310	2.13e-44	-	-	-	-	-	-	-	-
IOFPBDMD_00311	1.11e-44	-	-	-	-	-	-	-	-
IOFPBDMD_00312	4.93e-286	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IOFPBDMD_00313	5.56e-287	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IOFPBDMD_00314	1.38e-189	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IOFPBDMD_00316	3.96e-120	-	-	-	-	-	-	-	-
IOFPBDMD_00317	3.66e-36	-	-	-	V	-	-	-	MacB-like periplasmic core domain
IOFPBDMD_00318	6.62e-69	salX	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_00320	9.3e-172	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IOFPBDMD_00321	0.0	-	-	-	M	-	-	-	Cna protein B-type domain
IOFPBDMD_00322	0.0	-	-	-	M	-	-	-	domain protein
IOFPBDMD_00323	0.0	-	-	-	M	-	-	-	domain protein
IOFPBDMD_00324	4.45e-133	-	-	-	-	-	-	-	-
IOFPBDMD_00325	4.38e-285	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
IOFPBDMD_00326	4.88e-263	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
IOFPBDMD_00327	9.02e-125	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOFPBDMD_00328	5.62e-75	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
IOFPBDMD_00329	5.59e-176	-	-	-	-	-	-	-	-
IOFPBDMD_00330	1.93e-170	-	-	-	-	-	-	-	-
IOFPBDMD_00331	1.23e-58	-	-	-	S	-	-	-	Enterocin A Immunity
IOFPBDMD_00332	1.07e-237	tas	-	-	C	-	-	-	Aldo/keto reductase family
IOFPBDMD_00333	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
IOFPBDMD_00334	5.9e-78	-	-	-	-	-	-	-	-
IOFPBDMD_00335	3.87e-301	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
IOFPBDMD_00336	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IOFPBDMD_00337	1.27e-62	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOFPBDMD_00339	1.15e-121	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IOFPBDMD_00340	1.96e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
IOFPBDMD_00341	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
IOFPBDMD_00342	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IOFPBDMD_00343	9.91e-257	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IOFPBDMD_00344	6.34e-165	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
IOFPBDMD_00345	1.83e-187	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IOFPBDMD_00346	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
IOFPBDMD_00347	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	(ABC) transporter
IOFPBDMD_00348	1.05e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
IOFPBDMD_00349	1.15e-79	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
IOFPBDMD_00350	5.06e-181	-	-	-	-	-	-	-	-
IOFPBDMD_00351	1.54e-222	-	-	-	-	-	-	-	-
IOFPBDMD_00352	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
IOFPBDMD_00353	7.36e-250	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IOFPBDMD_00354	3.66e-229	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
IOFPBDMD_00355	4.19e-212	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
IOFPBDMD_00356	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IOFPBDMD_00357	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
IOFPBDMD_00358	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
IOFPBDMD_00359	8.92e-111	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
IOFPBDMD_00360	3.43e-281	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IOFPBDMD_00361	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
IOFPBDMD_00362	9.49e-143	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
IOFPBDMD_00363	1.9e-147	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IOFPBDMD_00364	7.79e-112	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
IOFPBDMD_00365	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
IOFPBDMD_00366	4.21e-156	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IOFPBDMD_00367	1.54e-136	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
IOFPBDMD_00368	5.37e-88	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IOFPBDMD_00370	5.02e-277	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
IOFPBDMD_00371	6.31e-223	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
IOFPBDMD_00372	7.29e-46	-	-	-	-	-	-	-	-
IOFPBDMD_00373	4.08e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
IOFPBDMD_00374	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
IOFPBDMD_00375	2.53e-210	lysR	-	-	K	-	-	-	Transcriptional regulator
IOFPBDMD_00377	2.95e-240	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOFPBDMD_00378	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOFPBDMD_00379	1.76e-51	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
IOFPBDMD_00380	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
IOFPBDMD_00381	4.86e-05	-	-	-	-	-	-	-	-
IOFPBDMD_00382	5.46e-72	-	-	-	-	-	-	-	-
IOFPBDMD_00383	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOFPBDMD_00384	1.72e-142	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
IOFPBDMD_00385	5.59e-90	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
IOFPBDMD_00386	5.76e-84	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
IOFPBDMD_00387	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
IOFPBDMD_00388	1.99e-106	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IOFPBDMD_00389	1.74e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IOFPBDMD_00390	3.67e-126	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IOFPBDMD_00391	2.33e-299	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
IOFPBDMD_00392	5.88e-229	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IOFPBDMD_00393	2.76e-306	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IOFPBDMD_00394	5.32e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IOFPBDMD_00395	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
IOFPBDMD_00396	9.32e-194	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IOFPBDMD_00397	1.55e-162	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IOFPBDMD_00398	3.69e-143	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IOFPBDMD_00399	3.31e-246	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
IOFPBDMD_00400	1.43e-67	-	-	-	S	-	-	-	MazG-like family
IOFPBDMD_00401	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
IOFPBDMD_00403	3.08e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
IOFPBDMD_00404	3.8e-130	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
IOFPBDMD_00405	1.99e-260	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Cys/Met metabolism PLP-dependent enzyme
IOFPBDMD_00406	1.1e-277	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IOFPBDMD_00407	1.34e-139	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IOFPBDMD_00408	3.62e-287	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IOFPBDMD_00409	9.96e-135	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
IOFPBDMD_00410	1.15e-144	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IOFPBDMD_00411	1.38e-170	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IOFPBDMD_00412	4.26e-171	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IOFPBDMD_00413	4.81e-76	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IOFPBDMD_00414	5.01e-69	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
IOFPBDMD_00415	4.53e-263	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IOFPBDMD_00416	3.82e-187	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
IOFPBDMD_00417	1.76e-145	-	-	-	C	-	-	-	Nitroreductase family
IOFPBDMD_00418	1.22e-93	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOFPBDMD_00419	7.37e-90	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOFPBDMD_00420	2.13e-277	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
IOFPBDMD_00421	1.24e-164	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
IOFPBDMD_00422	5.58e-221	-	-	-	T	-	-	-	Histidine kinase-like ATPases
IOFPBDMD_00423	5.18e-174	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_00424	0.0	XK27_05700	-	-	V	ko:K02004,ko:K19084	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	FtsX-like permease family
IOFPBDMD_00425	1.93e-265	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
IOFPBDMD_00426	3.94e-221	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
IOFPBDMD_00427	1.15e-235	-	-	-	K	-	-	-	LysR substrate binding domain
IOFPBDMD_00428	3.64e-217	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IOFPBDMD_00429	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
IOFPBDMD_00430	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOFPBDMD_00431	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOFPBDMD_00432	5.92e-142	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IOFPBDMD_00433	4.61e-220	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IOFPBDMD_00434	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IOFPBDMD_00435	2.06e-119	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IOFPBDMD_00436	3.34e-214	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
IOFPBDMD_00437	3.4e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IOFPBDMD_00438	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IOFPBDMD_00439	4.65e-189	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
IOFPBDMD_00440	1.61e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOFPBDMD_00441	7.5e-202	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IOFPBDMD_00442	3.27e-167	-	-	-	S	-	-	-	Domain of unknown function (DUF4918)
IOFPBDMD_00443	8.49e-12	-	-	-	-	-	-	-	-
IOFPBDMD_00444	6.03e-55	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
IOFPBDMD_00445	2.96e-57	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IOFPBDMD_00446	1.14e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
IOFPBDMD_00447	5.92e-97	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
IOFPBDMD_00448	4.62e-273	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
IOFPBDMD_00449	5.16e-192	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
IOFPBDMD_00450	8.13e-185	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
IOFPBDMD_00451	7.09e-179	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
IOFPBDMD_00452	6.48e-157	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOFPBDMD_00453	6.94e-70	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
IOFPBDMD_00454	5.34e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IOFPBDMD_00455	1.12e-303	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOFPBDMD_00456	2.32e-147	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IOFPBDMD_00457	3.78e-292	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IOFPBDMD_00458	3.14e-166	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
IOFPBDMD_00459	4.22e-216	p75	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
IOFPBDMD_00460	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
IOFPBDMD_00461	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
IOFPBDMD_00462	5.96e-185	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
IOFPBDMD_00463	3.11e-75	lacF-1	2.7.1.207	-	G	ko:K02786	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
IOFPBDMD_00464	4.73e-294	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOFPBDMD_00465	1.1e-197	-	-	-	-	-	-	-	-
IOFPBDMD_00466	1.81e-150	-	-	-	-	-	-	-	-
IOFPBDMD_00467	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
IOFPBDMD_00468	3.9e-304	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOFPBDMD_00469	1.74e-111	-	-	-	-	-	-	-	-
IOFPBDMD_00470	0.0	manR	-	-	G	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOFPBDMD_00471	1.34e-88	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOFPBDMD_00472	1.31e-305	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOFPBDMD_00473	1.66e-249	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IOFPBDMD_00474	1.43e-166	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
IOFPBDMD_00475	1.15e-280	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
IOFPBDMD_00476	5.31e-287	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IOFPBDMD_00477	0.0	bgaC	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
IOFPBDMD_00478	3.25e-107	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IOFPBDMD_00479	2.07e-179	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
IOFPBDMD_00480	3.66e-187	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
IOFPBDMD_00481	1.11e-84	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
IOFPBDMD_00482	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IOFPBDMD_00483	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IOFPBDMD_00484	1.33e-292	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
IOFPBDMD_00485	2.29e-294	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
IOFPBDMD_00486	9.39e-256	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IOFPBDMD_00487	0.0	-	-	-	U	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOFPBDMD_00488	2.02e-78	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOFPBDMD_00489	3.76e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
IOFPBDMD_00490	1.17e-247	-	-	-	E	-	-	-	M42 glutamyl aminopeptidase
IOFPBDMD_00491	0.0	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOFPBDMD_00492	1.3e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IOFPBDMD_00493	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IOFPBDMD_00494	2.24e-154	-	-	-	S	ko:K03824	-	ko00000,ko01000	Acetyltransferase (GNAT) family
IOFPBDMD_00495	6.53e-174	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
IOFPBDMD_00496	2.79e-125	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
IOFPBDMD_00497	4.39e-34	-	-	-	-	-	-	-	-
IOFPBDMD_00500	3.47e-112	-	-	-	-	-	-	-	-
IOFPBDMD_00502	7.46e-61	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPase activity
IOFPBDMD_00503	3.79e-28	-	-	-	-	-	-	-	-
IOFPBDMD_00505	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
IOFPBDMD_00506	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IOFPBDMD_00507	1.65e-116	-	-	-	-	-	-	-	-
IOFPBDMD_00508	1.92e-149	-	-	-	-	-	-	-	-
IOFPBDMD_00509	6.5e-162	-	-	-	-	-	-	-	-
IOFPBDMD_00510	2.8e-152	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOFPBDMD_00511	2.2e-97	-	-	-	-	-	-	-	-
IOFPBDMD_00512	5.25e-106	-	-	-	S	-	-	-	NUDIX domain
IOFPBDMD_00513	2.66e-271	-	-	-	S	-	-	-	nuclear-transcribed mRNA catabolic process, no-go decay
IOFPBDMD_00514	0.0	fnq20	-	-	S	-	-	-	FAD-NAD(P)-binding
IOFPBDMD_00515	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
IOFPBDMD_00516	6.18e-150	-	-	-	-	-	-	-	-
IOFPBDMD_00517	8.84e-274	-	-	-	S	ko:K06872	-	ko00000	TPM domain
IOFPBDMD_00518	2.86e-183	yunE	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
IOFPBDMD_00519	1.85e-73	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
IOFPBDMD_00520	1.47e-07	-	-	-	-	-	-	-	-
IOFPBDMD_00521	5.12e-84	-	-	-	-	-	-	-	-
IOFPBDMD_00522	7.43e-69	-	-	-	-	-	-	-	-
IOFPBDMD_00523	2.23e-107	-	-	-	C	-	-	-	Flavodoxin
IOFPBDMD_00524	4.57e-49	-	-	-	-	-	-	-	-
IOFPBDMD_00525	4.87e-37	-	-	-	-	-	-	-	-
IOFPBDMD_00526	5.78e-219	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOFPBDMD_00527	1.87e-93	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
IOFPBDMD_00528	1.55e-51	-	-	-	S	-	-	-	Transglycosylase associated protein
IOFPBDMD_00529	1.68e-116	-	-	-	S	-	-	-	Protein conserved in bacteria
IOFPBDMD_00530	1.32e-39	-	-	-	-	-	-	-	-
IOFPBDMD_00531	1.62e-80	asp23	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IOFPBDMD_00532	3.02e-87	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IOFPBDMD_00533	2.73e-166	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IOFPBDMD_00534	4.96e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
IOFPBDMD_00535	5.63e-186	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
IOFPBDMD_00536	5.7e-153	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IOFPBDMD_00537	1.89e-133	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
IOFPBDMD_00539	3.57e-165	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
IOFPBDMD_00540	2.32e-86	-	-	-	-	-	-	-	-
IOFPBDMD_00541	9.03e-173	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
IOFPBDMD_00542	5.2e-188	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IOFPBDMD_00543	3.67e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
IOFPBDMD_00544	6.39e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IOFPBDMD_00545	8.4e-42	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
IOFPBDMD_00546	4.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IOFPBDMD_00547	2.39e-182	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
IOFPBDMD_00548	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IOFPBDMD_00549	1.67e-152	-	-	-	-	-	-	-	-
IOFPBDMD_00550	1.68e-156	vanR	-	-	K	-	-	-	response regulator
IOFPBDMD_00551	1.45e-280	hpk31	-	-	T	-	-	-	Histidine kinase
IOFPBDMD_00552	5.54e-303	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IOFPBDMD_00553	2.55e-111	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOFPBDMD_00554	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IOFPBDMD_00555	1.83e-180	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
IOFPBDMD_00556	1.93e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
IOFPBDMD_00557	1.13e-181	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	DeoR C terminal sensor domain
IOFPBDMD_00558	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOFPBDMD_00559	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IOFPBDMD_00560	1.64e-198	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IOFPBDMD_00561	6.58e-227	iolC	2.7.1.92	-	H	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IOFPBDMD_00562	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IOFPBDMD_00563	1.12e-245	iolG	1.1.1.18, 1.1.1.369	-	C	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IOFPBDMD_00564	1.01e-250	iolG2	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
IOFPBDMD_00565	2.99e-222	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IOFPBDMD_00566	5.48e-202	iolJ	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
IOFPBDMD_00567	1.75e-87	yodA	-	-	S	-	-	-	Tautomerase enzyme
IOFPBDMD_00568	1.2e-203	-	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
IOFPBDMD_00569	2.1e-215	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
IOFPBDMD_00570	5.62e-190	gntR	-	-	K	-	-	-	rpiR family
IOFPBDMD_00571	1.6e-216	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
IOFPBDMD_00572	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
IOFPBDMD_00573	4.61e-270	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
IOFPBDMD_00574	3.08e-74	-	-	-	-	-	-	-	-
IOFPBDMD_00575	8.68e-169	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IOFPBDMD_00576	2.96e-173	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
IOFPBDMD_00577	6.52e-215	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
IOFPBDMD_00578	3.89e-205	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
IOFPBDMD_00579	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
IOFPBDMD_00580	6.87e-256	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IOFPBDMD_00581	7.52e-315	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IOFPBDMD_00582	4.98e-98	-	-	-	T	-	-	-	Sh3 type 3 domain protein
IOFPBDMD_00583	2.29e-175	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
IOFPBDMD_00584	5.69e-189	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IOFPBDMD_00585	6.35e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
IOFPBDMD_00586	4.9e-69	-	-	-	-	-	-	-	-
IOFPBDMD_00587	4.32e-138	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IOFPBDMD_00588	2.04e-224	-	3.2.2.24	-	O	ko:K05521	-	ko00000,ko01000	ADP-ribosylglycohydrolase
IOFPBDMD_00589	0.0	-	-	-	S	-	-	-	ABC transporter
IOFPBDMD_00590	1.5e-178	ksgA	2.1.1.182, 2.1.1.197, 2.5.1.134	-	J	ko:K02169,ko:K02528,ko:K17216,ko:K17462	ko00270,ko00780,ko01100,ko01230,map00270,map00780,map01100,map01230	ko00000,ko00001,ko00002,ko01000,ko03009	rRNA (adenine-N6,N6-)-dimethyltransferase activity
IOFPBDMD_00591	4.66e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOFPBDMD_00592	1.72e-208	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOFPBDMD_00593	1.14e-107	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOFPBDMD_00594	5.9e-15	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOFPBDMD_00595	4.39e-06	-	-	-	-	-	-	-	-
IOFPBDMD_00596	2.24e-72	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
IOFPBDMD_00597	1.63e-103	yphH	-	-	S	-	-	-	Cupin domain
IOFPBDMD_00598	1.2e-207	-	-	-	K	-	-	-	Transcriptional regulator
IOFPBDMD_00599	8.81e-166	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IOFPBDMD_00600	4.56e-215	bcrA	-	-	V	ko:K01990,ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IOFPBDMD_00601	1.38e-153	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
IOFPBDMD_00602	1.15e-204	-	-	-	T	-	-	-	GHKL domain
IOFPBDMD_00603	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IOFPBDMD_00604	9.53e-202	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
IOFPBDMD_00605	3.98e-171	-	-	-	F	-	-	-	deoxynucleoside kinase
IOFPBDMD_00606	1.02e-178	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
IOFPBDMD_00607	5.95e-212	-	-	-	IQ	-	-	-	NAD dependent epimerase/dehydratase family
IOFPBDMD_00608	1.4e-198	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IOFPBDMD_00609	2.9e-158	-	-	-	G	-	-	-	Phosphoglycerate mutase family
IOFPBDMD_00610	1.01e-192	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IOFPBDMD_00611	2.93e-158	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
IOFPBDMD_00612	4.72e-141	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
IOFPBDMD_00613	1.63e-95	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
IOFPBDMD_00614	0.0	-	6.3.2.2	-	M	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain protein
IOFPBDMD_00615	1.84e-302	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
IOFPBDMD_00616	1.41e-53	-	-	-	-	-	-	-	-
IOFPBDMD_00617	6.47e-110	uspA	-	-	T	-	-	-	universal stress protein
IOFPBDMD_00618	2.16e-206	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOFPBDMD_00619	3.54e-230	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
IOFPBDMD_00620	8.1e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
IOFPBDMD_00621	2.14e-36	-	-	-	-	-	-	-	-
IOFPBDMD_00623	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
IOFPBDMD_00624	1.42e-102	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
IOFPBDMD_00625	1.39e-281	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IOFPBDMD_00626	1.21e-243	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
IOFPBDMD_00627	2.4e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
IOFPBDMD_00628	5.58e-151	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOFPBDMD_00629	9.88e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IOFPBDMD_00630	8.69e-192	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IOFPBDMD_00631	1.56e-189	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IOFPBDMD_00632	2.56e-272	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
IOFPBDMD_00633	1.41e-63	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
IOFPBDMD_00634	1.35e-283	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
IOFPBDMD_00635	2.92e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
IOFPBDMD_00636	1.62e-72	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
IOFPBDMD_00637	5.48e-35	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
IOFPBDMD_00638	2.13e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
IOFPBDMD_00639	2.5e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
IOFPBDMD_00640	5.78e-19	-	-	-	-	-	-	-	-
IOFPBDMD_00641	6.51e-83	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IOFPBDMD_00642	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IOFPBDMD_00644	1.78e-211	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IOFPBDMD_00645	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IOFPBDMD_00646	4.59e-115	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOFPBDMD_00647	8.51e-72	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IOFPBDMD_00648	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOFPBDMD_00649	4.11e-161	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IOFPBDMD_00650	8.75e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IOFPBDMD_00651	1.29e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IOFPBDMD_00652	7.03e-246	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IOFPBDMD_00653	1.63e-196	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IOFPBDMD_00654	3.51e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IOFPBDMD_00655	8.22e-144	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
IOFPBDMD_00656	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
IOFPBDMD_00657	2.09e-244	ampC	-	-	V	-	-	-	Beta-lactamase
IOFPBDMD_00658	5.54e-210	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
IOFPBDMD_00659	2.49e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
IOFPBDMD_00660	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IOFPBDMD_00661	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_00662	5.26e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOFPBDMD_00663	3.56e-168	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
IOFPBDMD_00668	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IOFPBDMD_00669	8e-247	yttB	-	-	EGP	-	-	-	Major Facilitator
IOFPBDMD_00670	1.56e-25	-	-	-	-	-	-	-	-
IOFPBDMD_00678	4e-110	guaD	-	-	FJ	-	-	-	MafB19-like deaminase
IOFPBDMD_00679	3.12e-220	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
IOFPBDMD_00680	6.51e-293	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferases group 1
IOFPBDMD_00681	7.92e-102	-	-	-	S	-	-	-	Pfam Transposase IS66
IOFPBDMD_00682	7.26e-183	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
IOFPBDMD_00683	7.12e-62	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
IOFPBDMD_00685	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
IOFPBDMD_00686	5.43e-195	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
IOFPBDMD_00687	3.74e-142	vanZ	-	-	V	-	-	-	VanZ like family
IOFPBDMD_00688	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IOFPBDMD_00689	1.74e-83	-	-	-	-	-	-	-	-
IOFPBDMD_00690	9.5e-209	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOFPBDMD_00691	9.89e-243	-	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
IOFPBDMD_00692	1.37e-269	-	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
IOFPBDMD_00693	3.23e-204	p40	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
IOFPBDMD_00694	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IOFPBDMD_00695	3.54e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_00696	6.57e-125	-	-	-	K	-	-	-	transcriptional regulator
IOFPBDMD_00697	2.94e-195	-	-	-	G	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IOFPBDMD_00698	2.32e-60	-	-	-	-	-	-	-	-
IOFPBDMD_00699	1.29e-163	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IOFPBDMD_00700	8.48e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
IOFPBDMD_00701	1.86e-146	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
IOFPBDMD_00702	7.34e-72	-	-	-	-	-	-	-	-
IOFPBDMD_00704	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IOFPBDMD_00705	1.7e-142	-	-	-	S	-	-	-	Membrane
IOFPBDMD_00706	3.12e-111	-	-	-	-	-	-	-	-
IOFPBDMD_00707	5.38e-68	-	-	-	-	-	-	-	-
IOFPBDMD_00709	1.32e-300	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
IOFPBDMD_00710	3.24e-158	azlC	-	-	E	-	-	-	branched-chain amino acid
IOFPBDMD_00711	1.29e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
IOFPBDMD_00712	0.0	-	3.2.1.31	-	G	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
IOFPBDMD_00713	0.0	-	-	-	M	-	-	-	Glycosyl hydrolase family 59
IOFPBDMD_00714	5.06e-152	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
IOFPBDMD_00715	6.08e-227	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
IOFPBDMD_00716	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
IOFPBDMD_00717	4.1e-276	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
IOFPBDMD_00718	0.0	uxuB	1.1.1.57	-	G	ko:K00040	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase C-terminal domain
IOFPBDMD_00719	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain
IOFPBDMD_00720	6.58e-293	-	-	-	G	-	-	-	Major Facilitator
IOFPBDMD_00721	1.9e-163	kdgR	-	-	K	-	-	-	FCD domain
IOFPBDMD_00722	1.74e-242	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
IOFPBDMD_00723	0.0	-	-	-	M	-	-	-	Glycosyl hydrolase family 59
IOFPBDMD_00724	9.4e-76	ps105	-	-	-	-	-	-	-
IOFPBDMD_00725	3.77e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
IOFPBDMD_00726	1e-306	-	-	-	EGP	-	-	-	Major Facilitator
IOFPBDMD_00727	2.81e-279	-	3.1.1.83	-	I	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	ko00000,ko00001,ko01000	Alpha beta hydrolase
IOFPBDMD_00728	6.4e-60	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOFPBDMD_00729	5.25e-238	-	-	-	G	-	-	-	Melibiase
IOFPBDMD_00730	0.0	hylB	4.2.2.1	PL8	N	ko:K01727	-	ko00000,ko01000	Polysaccharide lyase family 8, N terminal alpha-helical domain
IOFPBDMD_00732	2.58e-156	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IOFPBDMD_00733	2.79e-192	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
IOFPBDMD_00734	6.85e-114	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
IOFPBDMD_00735	2.15e-175	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOFPBDMD_00736	1.8e-181	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IOFPBDMD_00737	5.57e-141	-	-	-	K	-	-	-	Bacterial transcriptional regulator
IOFPBDMD_00738	1.8e-131	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
IOFPBDMD_00739	7.7e-258	ugl	3.2.1.180	GH88	S	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
IOFPBDMD_00740	9.9e-105	-	-	-	G	ko:K02745	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IOFPBDMD_00741	4.89e-172	-	-	-	G	ko:K02746	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
IOFPBDMD_00742	7.09e-184	agaD	-	-	G	ko:K02747	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
IOFPBDMD_00743	1.78e-86	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
IOFPBDMD_00744	0.000638	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
IOFPBDMD_00745	0.0	-	-	-	M	-	-	-	Heparinase II/III N-terminus
IOFPBDMD_00746	6.74e-100	-	-	-	-	-	-	-	-
IOFPBDMD_00747	0.0	-	-	-	M	-	-	-	Right handed beta helix region
IOFPBDMD_00748	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IOFPBDMD_00749	5.54e-156	-	-	-	-	-	-	-	-
IOFPBDMD_00750	4.69e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
IOFPBDMD_00751	5.2e-276	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
IOFPBDMD_00752	4.24e-247	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IOFPBDMD_00753	0.0	iolF	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
IOFPBDMD_00754	0.0	rhaB	2.7.1.5	-	F	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
IOFPBDMD_00755	4.22e-74	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
IOFPBDMD_00756	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	L-rhamnose isomerase (RhaA)
IOFPBDMD_00757	6.22e-211	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
IOFPBDMD_00759	5.58e-156	rdrB	-	-	K	ko:K02444,ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
IOFPBDMD_00760	4.19e-89	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOFPBDMD_00761	6.21e-68	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOFPBDMD_00762	0.0	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
IOFPBDMD_00764	1.22e-165	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
IOFPBDMD_00765	3.16e-312	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
IOFPBDMD_00766	1.95e-94	-	-	-	K	-	-	-	Transcriptional regulator
IOFPBDMD_00767	1.49e-97	-	-	-	-	-	-	-	-
IOFPBDMD_00768	1.15e-203	-	-	-	K	-	-	-	LysR substrate binding domain
IOFPBDMD_00769	2.69e-310	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
IOFPBDMD_00770	1.32e-132	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IOFPBDMD_00771	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
IOFPBDMD_00773	1.49e-164	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOFPBDMD_00774	5.73e-82	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
IOFPBDMD_00775	6.17e-203	-	-	-	S	-	-	-	Alpha beta hydrolase
IOFPBDMD_00776	2.15e-237	-	-	-	K	-	-	-	Helix-turn-helix domain
IOFPBDMD_00777	6.02e-163	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IOFPBDMD_00778	0.0	ypiB	-	-	EGP	-	-	-	Major Facilitator
IOFPBDMD_00779	9.85e-147	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
IOFPBDMD_00780	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
IOFPBDMD_00781	5.54e-214	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOFPBDMD_00782	5e-174	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
IOFPBDMD_00783	4.82e-83	ORF00048	-	-	-	-	-	-	-
IOFPBDMD_00784	7.63e-74	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
IOFPBDMD_00785	1.29e-135	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
IOFPBDMD_00786	1.36e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOFPBDMD_00787	2.75e-123	kptA	-	-	J	ko:K07559	-	ko00000,ko01000,ko03016	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
IOFPBDMD_00788	4.38e-56	-	-	-	-	-	-	-	-
IOFPBDMD_00789	2.47e-308	citM	-	-	C	ko:K03300	-	ko00000	Citrate transporter
IOFPBDMD_00790	5.72e-69	-	-	-	-	-	-	-	-
IOFPBDMD_00791	1.44e-57	oadG	-	-	I	-	-	-	Biotin-requiring enzyme
IOFPBDMD_00792	1.6e-250	oadB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
IOFPBDMD_00793	4.63e-07	-	-	-	-	-	-	-	-
IOFPBDMD_00794	4.66e-232	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IOFPBDMD_00795	4.85e-65	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
IOFPBDMD_00796	2.5e-199	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
IOFPBDMD_00797	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
IOFPBDMD_00798	4.83e-131	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
IOFPBDMD_00799	0.0	oadA	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Conserved carboxylase domain
IOFPBDMD_00800	6.87e-162	citR	-	-	K	-	-	-	FCD
IOFPBDMD_00801	2.83e-202	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IOFPBDMD_00802	4.44e-62	-	-	-	-	-	-	-	-
IOFPBDMD_00803	1.37e-90	-	-	-	-	-	-	-	-
IOFPBDMD_00804	1.92e-83	-	-	-	-	-	-	-	-
IOFPBDMD_00805	1.2e-199	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IOFPBDMD_00806	3.21e-204	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IOFPBDMD_00807	1.43e-25	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IOFPBDMD_00808	1.42e-132	-	-	-	-	-	-	-	-
IOFPBDMD_00809	9.53e-241	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
IOFPBDMD_00810	2.4e-07	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOFPBDMD_00811	1.69e-125	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IOFPBDMD_00812	1.96e-126	-	-	-	-	-	-	-	-
IOFPBDMD_00813	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
IOFPBDMD_00814	1.97e-168	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
IOFPBDMD_00816	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
IOFPBDMD_00817	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
IOFPBDMD_00818	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
IOFPBDMD_00819	4.36e-284	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IOFPBDMD_00820	1.33e-85	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOFPBDMD_00821	7.35e-70	-	-	-	-	-	-	-	-
IOFPBDMD_00822	1.04e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IOFPBDMD_00823	5.57e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IOFPBDMD_00824	8.35e-84	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IOFPBDMD_00825	4.25e-85	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
IOFPBDMD_00826	2.95e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IOFPBDMD_00827	6.59e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
IOFPBDMD_00828	1.47e-90	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
IOFPBDMD_00829	5.66e-29	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
IOFPBDMD_00830	4.18e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IOFPBDMD_00831	6.26e-215	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IOFPBDMD_00832	7.61e-217	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOFPBDMD_00833	1.26e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
IOFPBDMD_00834	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IOFPBDMD_00835	1.8e-308	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
IOFPBDMD_00836	0.0	-	-	-	-	-	-	-	-
IOFPBDMD_00837	8.06e-200	-	-	-	V	-	-	-	ABC transporter
IOFPBDMD_00838	1.72e-103	-	-	-	FG	-	-	-	adenosine 5'-monophosphoramidase activity
IOFPBDMD_00839	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
IOFPBDMD_00840	2.95e-147	-	-	-	J	-	-	-	HAD-hyrolase-like
IOFPBDMD_00841	2.17e-97	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IOFPBDMD_00842	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOFPBDMD_00843	1.7e-70	-	-	-	-	-	-	-	-
IOFPBDMD_00844	7.38e-167	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IOFPBDMD_00845	5.37e-221	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
IOFPBDMD_00846	2.02e-112	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
IOFPBDMD_00847	2.26e-143	-	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
IOFPBDMD_00848	1.1e-50	-	-	-	-	-	-	-	-
IOFPBDMD_00849	9.77e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
IOFPBDMD_00850	3.45e-37	-	-	-	-	-	-	-	-
IOFPBDMD_00851	2.4e-80	-	-	-	-	-	-	-	-
IOFPBDMD_00853	1.6e-145	-	-	-	S	-	-	-	Flavodoxin-like fold
IOFPBDMD_00854	2.75e-118	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOFPBDMD_00855	5.29e-238	mocA	-	-	S	-	-	-	Oxidoreductase
IOFPBDMD_00856	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IOFPBDMD_00857	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IOFPBDMD_00859	0.0	-	2.4.1.9, 3.4.24.40	GH68	M	ko:K01406,ko:K20811	ko00500,ko01503,map00500,map01503	ko00000,ko00001,ko01000,ko01002	domain protein
IOFPBDMD_00861	0.0	-	-	-	-	-	-	-	-
IOFPBDMD_00862	1.75e-274	-	-	-	-	-	-	-	-
IOFPBDMD_00863	1.07e-238	-	-	-	-	-	-	-	-
IOFPBDMD_00864	5.46e-189	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	N-formylglutamate amidohydrolase
IOFPBDMD_00865	8.85e-72	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
IOFPBDMD_00866	2.18e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IOFPBDMD_00867	4.87e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IOFPBDMD_00868	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
IOFPBDMD_00869	2.01e-81	-	-	-	-	-	-	-	-
IOFPBDMD_00870	4.13e-109	-	-	-	S	-	-	-	ASCH
IOFPBDMD_00871	4.01e-44	-	-	-	-	-	-	-	-
IOFPBDMD_00872	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IOFPBDMD_00873	6.01e-268	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IOFPBDMD_00874	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IOFPBDMD_00875	2.41e-127	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IOFPBDMD_00876	2.27e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IOFPBDMD_00877	2.08e-286	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
IOFPBDMD_00878	2.57e-224	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
IOFPBDMD_00879	3.43e-206	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IOFPBDMD_00880	1.91e-152	yceF	-	-	P	ko:K05794	-	ko00000	membrane
IOFPBDMD_00881	1.27e-76	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IOFPBDMD_00882	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IOFPBDMD_00883	1.85e-59	ylxQ	-	-	J	-	-	-	ribosomal protein
IOFPBDMD_00884	2.02e-62	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
IOFPBDMD_00885	5.2e-273	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IOFPBDMD_00886	3.81e-110	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
IOFPBDMD_00887	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOFPBDMD_00888	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IOFPBDMD_00889	2.89e-291	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
IOFPBDMD_00890	9.72e-182	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
IOFPBDMD_00891	2.05e-177	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IOFPBDMD_00892	4.96e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IOFPBDMD_00893	1.96e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IOFPBDMD_00894	3.28e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IOFPBDMD_00895	9.72e-182	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IOFPBDMD_00896	1.29e-63	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
IOFPBDMD_00897	1.5e-173	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
IOFPBDMD_00898	4.02e-158	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
IOFPBDMD_00899	2.83e-301	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
IOFPBDMD_00900	7.66e-178	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
IOFPBDMD_00901	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOFPBDMD_00902	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOFPBDMD_00903	1.39e-40	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
IOFPBDMD_00904	3.45e-49	ynzC	-	-	S	-	-	-	UPF0291 protein
IOFPBDMD_00905	1.08e-35	-	-	-	-	-	-	-	-
IOFPBDMD_00906	1.16e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IOFPBDMD_00907	2.14e-189	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IOFPBDMD_00908	9.14e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IOFPBDMD_00909	2.2e-51	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
IOFPBDMD_00910	2.97e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IOFPBDMD_00911	1.02e-301	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IOFPBDMD_00912	2.45e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IOFPBDMD_00913	1.47e-33	-	-	-	-	-	-	-	-
IOFPBDMD_00914	1.12e-69	-	-	-	-	-	-	-	-
IOFPBDMD_00915	3.16e-233	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IOFPBDMD_00916	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
IOFPBDMD_00917	2.68e-159	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IOFPBDMD_00918	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IOFPBDMD_00919	6.51e-196	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFPBDMD_00920	8.93e-223	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOFPBDMD_00921	5.65e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOFPBDMD_00922	2.99e-247	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOFPBDMD_00923	9.22e-49	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IOFPBDMD_00924	1.16e-240	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IOFPBDMD_00925	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IOFPBDMD_00926	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
IOFPBDMD_00927	5.83e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IOFPBDMD_00928	3.26e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
IOFPBDMD_00929	1.1e-158	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
IOFPBDMD_00930	1.63e-148	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
IOFPBDMD_00931	2.45e-215	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IOFPBDMD_00932	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IOFPBDMD_00933	4.47e-175	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
IOFPBDMD_00934	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IOFPBDMD_00935	2.29e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IOFPBDMD_00936	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IOFPBDMD_00937	3.8e-273	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IOFPBDMD_00938	4.4e-47	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IOFPBDMD_00939	5.09e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IOFPBDMD_00940	4.46e-156	-	-	-	S	ko:K07001	-	ko00000	Patatin-like phospholipase
IOFPBDMD_00941	8.07e-68	-	-	-	-	-	-	-	-
IOFPBDMD_00942	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IOFPBDMD_00943	3.59e-97	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IOFPBDMD_00944	4.68e-196	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
IOFPBDMD_00945	2.27e-186	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IOFPBDMD_00946	2.87e-43	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOFPBDMD_00947	2.58e-310	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOFPBDMD_00948	9.8e-197	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IOFPBDMD_00949	1.29e-87	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IOFPBDMD_00950	8.72e-100	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
IOFPBDMD_00951	4.27e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IOFPBDMD_00952	1.51e-259	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IOFPBDMD_00953	1.6e-63	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
IOFPBDMD_00954	4.18e-73	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
IOFPBDMD_00955	1.18e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IOFPBDMD_00956	5.41e-43	-	-	-	-	-	-	-	-
IOFPBDMD_00957	1.77e-20	-	-	-	-	-	-	-	-
IOFPBDMD_00958	2.69e-297	-	-	-	S	-	-	-	Membrane
IOFPBDMD_00960	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
IOFPBDMD_00961	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IOFPBDMD_00962	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IOFPBDMD_00963	5.4e-80	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
IOFPBDMD_00964	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
IOFPBDMD_00965	6.73e-305	ynbB	-	-	P	-	-	-	aluminum resistance
IOFPBDMD_00966	3.41e-231	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IOFPBDMD_00967	2.75e-34	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
IOFPBDMD_00968	6.47e-95	yqhL	-	-	P	-	-	-	Rhodanese-like protein
IOFPBDMD_00969	4.82e-227	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
IOFPBDMD_00970	1.37e-54	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
IOFPBDMD_00971	8.99e-157	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
IOFPBDMD_00972	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IOFPBDMD_00973	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
IOFPBDMD_00974	1.91e-70	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
IOFPBDMD_00975	3.39e-148	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
IOFPBDMD_00976	2.79e-234	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOFPBDMD_00977	2.31e-166	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
IOFPBDMD_00978	6.1e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOFPBDMD_00979	1.98e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
IOFPBDMD_00980	2.75e-267	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IOFPBDMD_00981	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOFPBDMD_00982	4.32e-260	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IOFPBDMD_00983	1.19e-89	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
IOFPBDMD_00984	3.09e-122	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IOFPBDMD_00985	5e-175	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOFPBDMD_00986	1.45e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
IOFPBDMD_00987	9.37e-230	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOFPBDMD_00988	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOFPBDMD_00989	1.01e-157	csrR	-	-	K	-	-	-	response regulator
IOFPBDMD_00990	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IOFPBDMD_00991	1.14e-122	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
IOFPBDMD_00992	3.45e-263	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
IOFPBDMD_00993	1.19e-178	yqeM	-	-	Q	-	-	-	Methyltransferase
IOFPBDMD_00994	1.68e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IOFPBDMD_00995	9.21e-142	yqeK	-	-	H	-	-	-	Hydrolase, HD family
IOFPBDMD_00996	1.19e-150	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IOFPBDMD_00997	7.67e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
IOFPBDMD_00998	9.33e-275	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
IOFPBDMD_00999	4.16e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
IOFPBDMD_01000	4.06e-213	ykcA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOFPBDMD_01001	1.36e-243	mhqA_2	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOFPBDMD_01002	8.79e-156	mhqD	-	-	S	ko:K06999	-	ko00000	Dienelactone hydrolase family
IOFPBDMD_01003	2.91e-229	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
IOFPBDMD_01004	4.79e-129	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
IOFPBDMD_01005	1.44e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IOFPBDMD_01006	1.13e-36	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
IOFPBDMD_01007	2.6e-101	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IOFPBDMD_01008	7.83e-292	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
IOFPBDMD_01009	3e-07	-	-	-	-	-	-	-	-
IOFPBDMD_01010	3.94e-45	-	-	-	K	-	-	-	WYL domain
IOFPBDMD_01011	1.19e-160	-	-	-	S	-	-	-	SseB protein N-terminal domain
IOFPBDMD_01012	5.87e-86	-	-	-	-	-	-	-	-
IOFPBDMD_01013	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IOFPBDMD_01014	3.91e-217	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
IOFPBDMD_01015	2.78e-316	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
IOFPBDMD_01016	3.55e-104	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IOFPBDMD_01017	4.88e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IOFPBDMD_01018	1.15e-199	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IOFPBDMD_01019	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IOFPBDMD_01020	1.65e-151	ybhL	-	-	S	ko:K06890	-	ko00000	Inhibitor of apoptosis-promoting Bax1
IOFPBDMD_01021	7.54e-242	-	-	-	S	-	-	-	Cell surface protein
IOFPBDMD_01023	2.02e-174	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
IOFPBDMD_01024	0.0	-	-	-	N	-	-	-	domain, Protein
IOFPBDMD_01025	0.0	XK27_00195	-	-	K	-	-	-	Mga helix-turn-helix domain
IOFPBDMD_01026	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IOFPBDMD_01027	7.57e-34	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IOFPBDMD_01028	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IOFPBDMD_01030	1.63e-146	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOFPBDMD_01031	4.38e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
IOFPBDMD_01033	1.11e-154	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IOFPBDMD_01034	3.86e-190	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
IOFPBDMD_01035	0.000128	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOFPBDMD_01036	4.2e-284	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IOFPBDMD_01037	3.53e-170	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_01038	1.14e-96	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
IOFPBDMD_01039	2.79e-77	-	-	-	S	-	-	-	YtxH-like protein
IOFPBDMD_01040	2.5e-203	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IOFPBDMD_01041	3.57e-233	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
IOFPBDMD_01042	3.88e-73	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
IOFPBDMD_01043	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IOFPBDMD_01044	1.4e-198	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IOFPBDMD_01045	2.72e-97	argR1	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IOFPBDMD_01046	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
IOFPBDMD_01048	3.28e-87	-	-	-	-	-	-	-	-
IOFPBDMD_01049	1.93e-30	-	-	-	-	-	-	-	-
IOFPBDMD_01050	3.26e-226	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
IOFPBDMD_01051	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
IOFPBDMD_01052	9.38e-158	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IOFPBDMD_01053	1.8e-86	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IOFPBDMD_01054	1.63e-176	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
IOFPBDMD_01055	9.97e-119	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
IOFPBDMD_01056	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
IOFPBDMD_01057	5.63e-178	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOFPBDMD_01058	9.06e-159	rrp1	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
IOFPBDMD_01059	1.03e-263	-	-	-	T	ko:K19168	-	ko00000,ko02048	His Kinase A (phosphoacceptor) domain
IOFPBDMD_01060	1.09e-139	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IOFPBDMD_01061	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5	-	P	ko:K01533,ko:K01534	-	ko00000,ko01000	P-type ATPase
IOFPBDMD_01062	1.17e-101	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
IOFPBDMD_01063	1.59e-286	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
IOFPBDMD_01064	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
IOFPBDMD_01065	9.63e-130	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IOFPBDMD_01066	6.18e-238	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
IOFPBDMD_01067	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IOFPBDMD_01068	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOFPBDMD_01069	3.56e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOFPBDMD_01070	5.52e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOFPBDMD_01071	1.9e-171	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
IOFPBDMD_01072	5.81e-272	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IOFPBDMD_01073	6.02e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IOFPBDMD_01074	2.72e-135	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
IOFPBDMD_01076	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOFPBDMD_01077	2.98e-18	-	-	-	-	-	-	-	-
IOFPBDMD_01078	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IOFPBDMD_01079	1.02e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
IOFPBDMD_01080	6.69e-39	-	-	-	-	-	-	-	-
IOFPBDMD_01081	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
IOFPBDMD_01082	2.87e-62	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
IOFPBDMD_01083	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IOFPBDMD_01084	1.09e-306	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
IOFPBDMD_01085	4.36e-264	yueF	-	-	S	-	-	-	AI-2E family transporter
IOFPBDMD_01086	1.96e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IOFPBDMD_01087	1.16e-124	-	-	-	-	-	-	-	-
IOFPBDMD_01088	1.73e-134	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
IOFPBDMD_01089	7.6e-176	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
IOFPBDMD_01090	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
IOFPBDMD_01091	2.24e-84	-	-	-	-	-	-	-	-
IOFPBDMD_01092	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOFPBDMD_01093	6.82e-104	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
IOFPBDMD_01094	0.0	poxL	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IOFPBDMD_01096	8.72e-279	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
IOFPBDMD_01097	4.29e-265	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
IOFPBDMD_01098	7.3e-268	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IOFPBDMD_01099	6.7e-62	-	-	-	-	-	-	-	-
IOFPBDMD_01100	5.52e-204	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
IOFPBDMD_01101	1.49e-132	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
IOFPBDMD_01102	2.96e-204	-	-	-	G	-	-	-	Aldose 1-epimerase
IOFPBDMD_01103	4.58e-269	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
IOFPBDMD_01104	6.88e-129	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
IOFPBDMD_01106	1.4e-105	-	-	-	K	-	-	-	FR47-like protein
IOFPBDMD_01107	8.49e-105	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
IOFPBDMD_01108	1.59e-165	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_01109	1.25e-175	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IOFPBDMD_01110	1.88e-225	XK27_08835	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
IOFPBDMD_01111	2.37e-95	-	-	-	-	-	-	-	-
IOFPBDMD_01112	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
IOFPBDMD_01113	1.01e-275	-	-	-	V	-	-	-	Beta-lactamase
IOFPBDMD_01114	4.16e-194	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IOFPBDMD_01115	1.3e-284	-	-	-	V	-	-	-	Beta-lactamase
IOFPBDMD_01116	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IOFPBDMD_01117	2.79e-162	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
IOFPBDMD_01118	2.49e-278	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IOFPBDMD_01119	7.93e-178	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOFPBDMD_01120	0.0	yuxL	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
IOFPBDMD_01121	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
IOFPBDMD_01122	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
IOFPBDMD_01124	1.92e-200	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IOFPBDMD_01125	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
IOFPBDMD_01126	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_01127	2.43e-87	-	-	-	-	-	-	-	-
IOFPBDMD_01128	1.39e-96	-	-	-	S	-	-	-	function, without similarity to other proteins
IOFPBDMD_01129	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
IOFPBDMD_01130	1.17e-295	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
IOFPBDMD_01131	3.89e-75	-	-	-	-	-	-	-	-
IOFPBDMD_01132	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
IOFPBDMD_01133	4.52e-34	-	-	-	S	-	-	-	Virus attachment protein p12 family
IOFPBDMD_01134	3.41e-313	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
IOFPBDMD_01135	9.93e-175	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
IOFPBDMD_01136	3.58e-128	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA
IOFPBDMD_01137	5.26e-153	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
IOFPBDMD_01138	1.12e-115	-	-	-	E	-	-	-	AAA domain
IOFPBDMD_01141	2.62e-152	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
IOFPBDMD_01142	2.78e-118	-	-	-	S	-	-	-	MucBP domain
IOFPBDMD_01143	5.24e-113	-	-	-	-	-	-	-	-
IOFPBDMD_01147	1.13e-271	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IOFPBDMD_01149	9.91e-28	-	-	-	-	-	-	-	-
IOFPBDMD_01150	4.33e-121	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
IOFPBDMD_01151	1.4e-24	-	-	-	K	-	-	-	Peptidase S24-like
IOFPBDMD_01152	3.44e-48	-	-	-	K	-	-	-	Helix-turn-helix
IOFPBDMD_01154	2.51e-40	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
IOFPBDMD_01155	2.04e-106	-	-	-	S	-	-	-	Phage regulatory protein Rha (Phage_pRha)
IOFPBDMD_01162	1.25e-137	-	-	-	S	-	-	-	calcium ion binding
IOFPBDMD_01163	3.14e-294	-	-	-	S	-	-	-	DNA helicase activity
IOFPBDMD_01166	1.88e-52	-	-	-	-	-	-	-	-
IOFPBDMD_01167	2.27e-86	-	-	-	S	-	-	-	magnesium ion binding
IOFPBDMD_01168	1.59e-34	-	-	-	-	-	-	-	-
IOFPBDMD_01169	3.26e-36	-	-	-	-	-	-	-	-
IOFPBDMD_01170	3.21e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1642)
IOFPBDMD_01172	4.83e-45	-	-	-	-	-	-	-	-
IOFPBDMD_01174	1.55e-101	-	-	-	-	-	-	-	-
IOFPBDMD_01176	1.57e-300	-	-	-	-	-	-	-	-
IOFPBDMD_01177	9.45e-126	-	-	-	S	-	-	-	HNH endonuclease
IOFPBDMD_01178	3.63e-67	-	-	-	-	-	-	-	-
IOFPBDMD_01179	4.14e-90	-	-	-	S	-	-	-	HNH endonuclease
IOFPBDMD_01180	2.95e-101	-	-	-	S	-	-	-	Phage terminase, small subunit
IOFPBDMD_01181	0.0	-	-	-	S	-	-	-	Phage Terminase
IOFPBDMD_01183	4.22e-286	-	-	-	S	-	-	-	Phage portal protein
IOFPBDMD_01184	3.52e-135	-	-	-	S	-	-	-	peptidase activity
IOFPBDMD_01185	1.71e-263	-	-	-	S	-	-	-	peptidase activity
IOFPBDMD_01186	2.4e-37	-	-	-	S	-	-	-	peptidase activity
IOFPBDMD_01187	3.59e-35	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
IOFPBDMD_01188	9.69e-53	-	-	-	S	-	-	-	Phage head-tail joining protein
IOFPBDMD_01189	1.62e-87	-	-	-	S	-	-	-	exonuclease activity
IOFPBDMD_01190	3.76e-38	-	-	-	-	-	-	-	-
IOFPBDMD_01191	1.91e-95	-	-	-	S	-	-	-	Pfam:Phage_TTP_1
IOFPBDMD_01192	2.72e-27	-	-	-	-	-	-	-	-
IOFPBDMD_01193	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
IOFPBDMD_01194	4.82e-51	-	-	-	S	-	-	-	phage tail
IOFPBDMD_01195	6.46e-53	-	-	-	M	-	-	-	Prophage endopeptidase tail
IOFPBDMD_01196	2.47e-61	-	-	-	M	-	-	-	CotH kinase protein
IOFPBDMD_01197	2.09e-63	-	-	-	-	-	-	-	-
IOFPBDMD_01198	3.43e-82	hol	-	-	S	-	-	-	Bacteriophage holin
IOFPBDMD_01199	6.45e-41	-	-	-	-	-	-	-	-
IOFPBDMD_01200	7.71e-259	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
IOFPBDMD_01203	6.04e-12	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
IOFPBDMD_01204	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOFPBDMD_01205	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOFPBDMD_01206	3.29e-258	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IOFPBDMD_01207	2.87e-43	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
IOFPBDMD_01209	4.16e-260	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IOFPBDMD_01210	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IOFPBDMD_01211	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
IOFPBDMD_01213	1.56e-78	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IOFPBDMD_01214	8.28e-182	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOFPBDMD_01215	3.01e-177	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
IOFPBDMD_01216	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IOFPBDMD_01217	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IOFPBDMD_01218	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
IOFPBDMD_01219	6.61e-41	-	-	-	-	-	-	-	-
IOFPBDMD_01221	3.65e-173	-	-	-	S	-	-	-	Putative threonine/serine exporter
IOFPBDMD_01222	1.8e-105	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
IOFPBDMD_01223	2.84e-284	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
IOFPBDMD_01226	1.43e-251	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	dehydrogenase
IOFPBDMD_01227	1.22e-76	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOFPBDMD_01230	9e-191	-	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
IOFPBDMD_01231	5.63e-180	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
IOFPBDMD_01232	1.58e-285	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IOFPBDMD_01233	1.23e-306	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
IOFPBDMD_01234	0.0	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
IOFPBDMD_01235	4.23e-237	-	-	-	-	-	-	-	-
IOFPBDMD_01236	2.91e-39	-	-	-	-	-	-	-	-
IOFPBDMD_01237	3.85e-94	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOFPBDMD_01238	4.41e-113	-	-	-	C	-	-	-	nadph quinone reductase
IOFPBDMD_01239	3.88e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
IOFPBDMD_01240	2.05e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOFPBDMD_01241	1.77e-194	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IOFPBDMD_01242	2.08e-283	-	-	-	K	-	-	-	IrrE N-terminal-like domain
IOFPBDMD_01243	1.23e-175	-	-	-	-	-	-	-	-
IOFPBDMD_01244	1.29e-25	-	-	-	-	-	-	-	-
IOFPBDMD_01245	7.2e-60	-	-	-	-	-	-	-	-
IOFPBDMD_01246	2.23e-191	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IOFPBDMD_01247	2.92e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOFPBDMD_01248	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOFPBDMD_01249	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
IOFPBDMD_01250	5.35e-102	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOFPBDMD_01251	1.75e-275	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
IOFPBDMD_01252	9.48e-237	lipA	-	-	I	-	-	-	Carboxylesterase family
IOFPBDMD_01253	2.32e-233	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
IOFPBDMD_01254	3.77e-217	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOFPBDMD_01256	7.89e-216	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IOFPBDMD_01257	4.52e-169	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
IOFPBDMD_01258	3.93e-90	-	-	-	-	-	-	-	-
IOFPBDMD_01259	1.96e-192	-	-	-	I	-	-	-	NAD binding domain of 6-phosphogluconate dehydrogenase
IOFPBDMD_01261	3.32e-150	-	1.1.1.29	-	CH	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOFPBDMD_01262	1.43e-123	-	-	-	-	-	-	-	-
IOFPBDMD_01263	4.99e-154	malR	-	-	KT	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
IOFPBDMD_01264	0.0	dpiB	2.7.13.3	-	T	ko:K02476,ko:K11614	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Single cache domain 3
IOFPBDMD_01265	1.04e-289	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	2-hydroxycarboxylate transporter family
IOFPBDMD_01266	1.12e-250	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
IOFPBDMD_01269	3.8e-150	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
IOFPBDMD_01270	2.08e-58	-	-	-	M	-	-	-	Glycosyl transferase family 8
IOFPBDMD_01271	1.06e-39	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
IOFPBDMD_01272	1.09e-270	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IOFPBDMD_01273	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOFPBDMD_01274	0.0	bglH	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOFPBDMD_01275	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
IOFPBDMD_01276	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IOFPBDMD_01277	3.76e-107	-	-	-	S	-	-	-	Fic/DOC family
IOFPBDMD_01278	4.96e-219	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
IOFPBDMD_01279	5.01e-142	-	-	-	-	-	-	-	-
IOFPBDMD_01280	2.84e-215	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
IOFPBDMD_01281	6.22e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
IOFPBDMD_01282	1.73e-35	-	-	-	T	-	-	-	PFAM SpoVT AbrB
IOFPBDMD_01283	2.8e-105	yvbK	-	-	K	-	-	-	GNAT family
IOFPBDMD_01284	1.84e-147	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
IOFPBDMD_01285	7.6e-131	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IOFPBDMD_01286	1.87e-304	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
IOFPBDMD_01287	2.43e-263	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IOFPBDMD_01288	1.74e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IOFPBDMD_01290	1.8e-134	-	-	-	-	-	-	-	-
IOFPBDMD_01291	6.43e-42	-	-	-	-	-	-	-	-
IOFPBDMD_01292	4.82e-184	srlD	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
IOFPBDMD_01293	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
IOFPBDMD_01294	2.53e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
IOFPBDMD_01295	1.43e-131	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
IOFPBDMD_01296	1.88e-252	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
IOFPBDMD_01297	1.74e-82	-	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
IOFPBDMD_01298	2.41e-158	-	-	-	H	-	-	-	Pfam:Transaldolase
IOFPBDMD_01299	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
IOFPBDMD_01300	1.33e-70	-	-	-	S	-	-	-	PRD domain
IOFPBDMD_01301	1.23e-80	-	-	-	S	-	-	-	Glycine-rich SFCGS
IOFPBDMD_01302	6.76e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF4312)
IOFPBDMD_01303	2.89e-177	-	-	-	S	-	-	-	Domain of unknown function (DUF4311)
IOFPBDMD_01304	1.94e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4310)
IOFPBDMD_01305	3.01e-275	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
IOFPBDMD_01306	3.41e-257	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
IOFPBDMD_01307	1.96e-177	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
IOFPBDMD_01309	2.14e-13	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IOFPBDMD_01310	2.22e-78	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IOFPBDMD_01311	3.33e-161	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IOFPBDMD_01312	6.58e-136	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
IOFPBDMD_01313	4.66e-259	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IOFPBDMD_01314	0.0	-	2.7.1.199, 2.7.1.208	-	G	ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
IOFPBDMD_01315	0.0	-	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
IOFPBDMD_01316	8.53e-65	araR	-	-	K	ko:K02103	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
IOFPBDMD_01317	9.21e-30	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
IOFPBDMD_01318	2.21e-79	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
IOFPBDMD_01319	5.55e-83	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
IOFPBDMD_01320	9.75e-54	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IOFPBDMD_01321	2.18e-247	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IOFPBDMD_01323	7.19e-209	menA	2.5.1.74	-	M	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
IOFPBDMD_01324	2.18e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
IOFPBDMD_01325	3.75e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IOFPBDMD_01326	2.53e-31	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IOFPBDMD_01327	8e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IOFPBDMD_01328	1.64e-203	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IOFPBDMD_01329	6.51e-103	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	nucleoside 2-deoxyribosyltransferase
IOFPBDMD_01330	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
IOFPBDMD_01331	2.89e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
IOFPBDMD_01332	5.8e-113	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
IOFPBDMD_01333	5.42e-117	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
IOFPBDMD_01334	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
IOFPBDMD_01335	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
IOFPBDMD_01336	1.97e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IOFPBDMD_01337	1.33e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IOFPBDMD_01338	4.45e-122	yqaB	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IOFPBDMD_01339	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IOFPBDMD_01340	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IOFPBDMD_01341	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IOFPBDMD_01342	1.45e-46	-	-	-	-	-	-	-	-
IOFPBDMD_01345	1.13e-93	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
IOFPBDMD_01371	7.81e-94	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
IOFPBDMD_01372	0.0	ybeC	-	-	E	-	-	-	amino acid
IOFPBDMD_01373	6.32e-294	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IOFPBDMD_01374	7.35e-249	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IOFPBDMD_01375	4.38e-222	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IOFPBDMD_01376	1.51e-279	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IOFPBDMD_01377	1.4e-58	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
IOFPBDMD_01378	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IOFPBDMD_01379	1.8e-104	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
IOFPBDMD_01380	3.7e-298	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
IOFPBDMD_01381	2.95e-207	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOFPBDMD_01382	1.12e-285	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IOFPBDMD_01383	2.08e-110	-	-	-	-	-	-	-	-
IOFPBDMD_01384	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_01385	1.03e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IOFPBDMD_01386	1.48e-118	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IOFPBDMD_01387	9.09e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
IOFPBDMD_01388	2.79e-190	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
IOFPBDMD_01389	3.87e-202	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IOFPBDMD_01390	5.89e-145	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
IOFPBDMD_01391	1.41e-125	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IOFPBDMD_01392	2.52e-55	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
IOFPBDMD_01393	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
IOFPBDMD_01396	1.03e-281	yceI	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
IOFPBDMD_01397	7.9e-218	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
IOFPBDMD_01398	6.19e-109	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IOFPBDMD_01399	4.57e-73	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IOFPBDMD_01400	1.62e-199	-	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IOFPBDMD_01401	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IOFPBDMD_01402	1.22e-220	ccpB	-	-	K	-	-	-	lacI family
IOFPBDMD_01403	7.81e-88	-	-	-	-	-	-	-	-
IOFPBDMD_01406	5.66e-08	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IOFPBDMD_01407	8.99e-99	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
IOFPBDMD_01408	2.26e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IOFPBDMD_01409	4.51e-127	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IOFPBDMD_01410	3.26e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IOFPBDMD_01411	5.33e-119	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
IOFPBDMD_01412	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
IOFPBDMD_01413	2.05e-233	-	-	-	C	-	-	-	Cytochrome bd terminal oxidase subunit II
IOFPBDMD_01414	7.17e-39	-	-	-	-	-	-	-	-
IOFPBDMD_01415	7.49e-138	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IOFPBDMD_01416	4.82e-109	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Best Blastp hit gi 7514214 pir G75157 'abc transporter, ATP-binding protein, puta tive PAB2069 - Pyrococcus abyssi (strain Orsay)' gi 5457852 emb CAB49342.1 '(AJ248284) ABC transporter, ATP-binding protein, puta tive Pyrococcus abyssi ', score 77, E-value 3.00E-13
IOFPBDMD_01417	1.13e-278	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IOFPBDMD_01418	7.5e-190	cad	-	-	S	ko:K20379	ko02024,map02024	ko00000,ko00001	FMN_bind
IOFPBDMD_01419	9.57e-15	-	-	-	G	-	-	-	Acyltransferase family
IOFPBDMD_01421	1e-138	-	-	-	-	-	-	-	-
IOFPBDMD_01422	1.66e-269	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IOFPBDMD_01423	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
IOFPBDMD_01424	3.41e-107	-	-	-	K	-	-	-	MerR HTH family regulatory protein
IOFPBDMD_01425	5.48e-274	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
IOFPBDMD_01426	6.18e-45	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
IOFPBDMD_01427	1.25e-153	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
IOFPBDMD_01428	2.47e-154	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
IOFPBDMD_01429	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IOFPBDMD_01430	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IOFPBDMD_01431	6.61e-167	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IOFPBDMD_01432	8.09e-48	yhcC	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
IOFPBDMD_01433	2.06e-174	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IOFPBDMD_01434	9.29e-123	-	-	-	F	-	-	-	NUDIX domain
IOFPBDMD_01436	3.41e-112	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
IOFPBDMD_01437	1.49e-287	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
IOFPBDMD_01438	5.43e-281	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IOFPBDMD_01439	1.19e-50	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
IOFPBDMD_01440	3.14e-310	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
IOFPBDMD_01441	1.17e-270	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
IOFPBDMD_01442	8.12e-151	yjbH	-	-	Q	-	-	-	Thioredoxin
IOFPBDMD_01443	8.17e-135	-	-	-	S	-	-	-	CYTH
IOFPBDMD_01444	4.15e-160	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
IOFPBDMD_01445	2.24e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IOFPBDMD_01446	5.18e-221	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IOFPBDMD_01447	3.99e-258	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IOFPBDMD_01448	1.51e-144	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
IOFPBDMD_01449	1.61e-185	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IOFPBDMD_01450	3.13e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
IOFPBDMD_01451	7.55e-82	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
IOFPBDMD_01452	4.12e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOFPBDMD_01453	9.97e-245	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IOFPBDMD_01454	9.63e-220	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
IOFPBDMD_01455	9.45e-198	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
IOFPBDMD_01456	6.48e-125	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IOFPBDMD_01457	8.84e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
IOFPBDMD_01458	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IOFPBDMD_01459	7.4e-293	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
IOFPBDMD_01460	3.94e-309	ymfH	-	-	S	-	-	-	Peptidase M16
IOFPBDMD_01461	1.43e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
IOFPBDMD_01462	1.8e-167	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
IOFPBDMD_01463	7.88e-135	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOFPBDMD_01464	3.23e-288	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
IOFPBDMD_01465	6.68e-240	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IOFPBDMD_01466	1.28e-07	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOFPBDMD_01467	2.37e-29	-	-	-	-	-	-	-	-
IOFPBDMD_01468	0.0	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
IOFPBDMD_01469	1.57e-151	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
IOFPBDMD_01470	3.04e-297	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
IOFPBDMD_01471	1.8e-117	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
IOFPBDMD_01472	7.96e-127	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IOFPBDMD_01473	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IOFPBDMD_01474	6.43e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IOFPBDMD_01475	2.59e-160	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	ABC transporter
IOFPBDMD_01476	4.17e-204	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IOFPBDMD_01477	7.95e-251	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
IOFPBDMD_01478	9.79e-168	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IOFPBDMD_01479	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOFPBDMD_01480	5.25e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
IOFPBDMD_01481	1.56e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IOFPBDMD_01482	3.55e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
IOFPBDMD_01483	1.83e-191	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOFPBDMD_01484	1.75e-180	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOFPBDMD_01485	1.33e-156	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
IOFPBDMD_01486	0.0	yvlB	-	-	S	-	-	-	Putative adhesin
IOFPBDMD_01487	7.01e-49	-	-	-	-	-	-	-	-
IOFPBDMD_01488	2.28e-61	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
IOFPBDMD_01489	5.82e-223	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IOFPBDMD_01490	2e-201	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IOFPBDMD_01491	1.8e-249	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
IOFPBDMD_01492	8.36e-230	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IOFPBDMD_01493	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IOFPBDMD_01494	2.18e-109	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
IOFPBDMD_01495	3.28e-143	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
IOFPBDMD_01496	1.21e-117	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOFPBDMD_01497	4.45e-105	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOFPBDMD_01498	2.3e-178	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOFPBDMD_01499	2.32e-152	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
IOFPBDMD_01500	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IOFPBDMD_01501	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IOFPBDMD_01502	2.98e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
IOFPBDMD_01503	1.47e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IOFPBDMD_01504	8.22e-246	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
IOFPBDMD_01505	3.36e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IOFPBDMD_01506	1.8e-47	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
IOFPBDMD_01507	1.43e-32	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
IOFPBDMD_01508	1.71e-131	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IOFPBDMD_01510	2.73e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
IOFPBDMD_01511	2.99e-247	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IOFPBDMD_01512	1.52e-282	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
IOFPBDMD_01513	8.05e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IOFPBDMD_01514	5.04e-314	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IOFPBDMD_01515	5.53e-84	-	-	-	-	-	-	-	-
IOFPBDMD_01516	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
IOFPBDMD_01517	1.48e-78	-	-	-	-	-	-	-	-
IOFPBDMD_01518	2.92e-42	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
IOFPBDMD_01519	3.69e-177	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
IOFPBDMD_01520	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IOFPBDMD_01521	9.03e-108	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IOFPBDMD_01522	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IOFPBDMD_01523	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
IOFPBDMD_01524	3.38e-149	-	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IOFPBDMD_01525	7.78e-66	-	-	-	-	-	-	-	-
IOFPBDMD_01527	6.97e-304	YSH1	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Metallo-beta-lactamase superfamily
IOFPBDMD_01528	5.23e-313	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOFPBDMD_01529	1.1e-188	malF	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFPBDMD_01530	1.21e-213	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
IOFPBDMD_01531	3.49e-248	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOFPBDMD_01532	7.94e-134	-	-	-	K	ko:K06977	-	ko00000	Acetyltransferase (GNAT) domain
IOFPBDMD_01533	5.33e-119	-	-	-	-	-	-	-	-
IOFPBDMD_01534	4.87e-204	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IOFPBDMD_01535	4.68e-168	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IOFPBDMD_01536	6.35e-230	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
IOFPBDMD_01537	1.2e-106	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
IOFPBDMD_01538	2.96e-210	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_01539	2.05e-278	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IOFPBDMD_01540	1.62e-128	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IOFPBDMD_01541	3.32e-191	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IOFPBDMD_01542	2.74e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
IOFPBDMD_01543	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
IOFPBDMD_01544	4.84e-125	-	-	-	K	-	-	-	Cupin domain
IOFPBDMD_01545	9.49e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IOFPBDMD_01546	2.13e-191	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOFPBDMD_01547	7.08e-187	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOFPBDMD_01548	2.08e-267	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOFPBDMD_01549	3.85e-116	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
IOFPBDMD_01550	2.37e-79	-	-	-	-	-	-	-	-
IOFPBDMD_01552	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
IOFPBDMD_01553	7.67e-152	-	-	-	K	-	-	-	Transcriptional regulator
IOFPBDMD_01554	1.16e-234	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IOFPBDMD_01555	1.12e-162	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IOFPBDMD_01556	2.69e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IOFPBDMD_01557	2.39e-221	ybbR	-	-	S	-	-	-	YbbR-like protein
IOFPBDMD_01558	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IOFPBDMD_01559	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IOFPBDMD_01560	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
IOFPBDMD_01561	1.8e-119	-	-	-	S	-	-	-	VanZ like family
IOFPBDMD_01562	1.75e-170	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
IOFPBDMD_01563	5.7e-183	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
IOFPBDMD_01564	1.91e-211	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
IOFPBDMD_01565	2e-64	-	-	-	-	ko:K02245	-	ko00000,ko00002,ko02044	-
IOFPBDMD_01567	3.45e-63	-	-	-	-	-	-	-	-
IOFPBDMD_01568	2.14e-105	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
IOFPBDMD_01569	1.84e-65	-	-	-	-	-	-	-	-
IOFPBDMD_01570	3.7e-235	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
IOFPBDMD_01571	1.58e-96	-	-	-	-	-	-	-	-
IOFPBDMD_01572	1.03e-314	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IOFPBDMD_01573	1.34e-184	arbV	-	-	I	-	-	-	Phosphate acyltransferases
IOFPBDMD_01574	1.36e-210	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
IOFPBDMD_01575	6.11e-229	arbY	-	-	M	-	-	-	family 8
IOFPBDMD_01576	2.93e-207	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
IOFPBDMD_01577	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
IOFPBDMD_01578	3.37e-272	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IOFPBDMD_01579	2.61e-06	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IOFPBDMD_01580	5.48e-57	-	-	-	-	-	-	-	-
IOFPBDMD_01581	8.37e-42	-	-	-	-	-	-	-	-
IOFPBDMD_01582	1.75e-16	-	-	-	-	-	-	-	-
IOFPBDMD_01583	7.95e-29	-	-	-	-	-	-	-	-
IOFPBDMD_01584	3.96e-48	-	-	-	-	-	-	-	-
IOFPBDMD_01585	1.18e-34	-	-	-	-	-	-	-	-
IOFPBDMD_01586	1.29e-197	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
IOFPBDMD_01587	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
IOFPBDMD_01589	9.4e-105	terS	-	-	L	-	-	-	Phage terminase, small subunit
IOFPBDMD_01590	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
IOFPBDMD_01591	1.22e-28	-	-	-	-	-	-	-	-
IOFPBDMD_01592	4.16e-279	-	-	-	S	-	-	-	Phage portal protein
IOFPBDMD_01593	0.0	-	-	-	S	ko:K06904	-	ko00000	Phage capsid family
IOFPBDMD_01594	1.88e-62	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
IOFPBDMD_01595	2.68e-17	-	-	-	S	-	-	-	Phage head-tail joining protein
IOFPBDMD_01596	2.3e-23	-	-	-	-	-	-	-	-
IOFPBDMD_01597	1.4e-35	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
IOFPBDMD_01598	1.26e-52	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IOFPBDMD_01600	1.55e-91	-	-	-	S	-	-	-	SdpI/YhfL protein family
IOFPBDMD_01601	3.15e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
IOFPBDMD_01602	0.0	yclK	-	-	T	-	-	-	Histidine kinase
IOFPBDMD_01603	1.9e-121	-	-	-	S	-	-	-	acetyltransferase
IOFPBDMD_01604	2.21e-42	-	-	-	-	-	-	-	-
IOFPBDMD_01605	1.49e-93	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
IOFPBDMD_01606	2.24e-106	-	-	-	-	-	-	-	-
IOFPBDMD_01607	1.41e-77	-	-	-	-	-	-	-	-
IOFPBDMD_01608	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
IOFPBDMD_01610	1.42e-254	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
IOFPBDMD_01611	2.4e-163	-	3.1.1.5	-	E	ko:K10804	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	GDSL-like Lipase/Acylhydrolase
IOFPBDMD_01612	1.3e-51	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
IOFPBDMD_01613	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
IOFPBDMD_01614	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IOFPBDMD_01615	2.36e-260	camS	-	-	S	-	-	-	sex pheromone
IOFPBDMD_01616	1.26e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOFPBDMD_01617	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IOFPBDMD_01618	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOFPBDMD_01619	1.42e-247	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
IOFPBDMD_01620	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOFPBDMD_01621	8.36e-277	yttB	-	-	EGP	-	-	-	Major Facilitator
IOFPBDMD_01622	8.04e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IOFPBDMD_01623	2.97e-211	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
IOFPBDMD_01624	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
IOFPBDMD_01625	7.53e-104	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOFPBDMD_01626	7.88e-211	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
IOFPBDMD_01627	1.95e-166	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
IOFPBDMD_01628	1.05e-40	-	-	-	-	-	-	-	-
IOFPBDMD_01629	1.28e-171	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
IOFPBDMD_01630	3.83e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
IOFPBDMD_01631	3.98e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
IOFPBDMD_01632	1.14e-228	mocA	-	-	S	-	-	-	Oxidoreductase
IOFPBDMD_01633	5.1e-301	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
IOFPBDMD_01634	2.05e-63	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
IOFPBDMD_01635	1.1e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
IOFPBDMD_01637	5.65e-07	-	-	-	-	-	-	-	-
IOFPBDMD_01638	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
IOFPBDMD_01639	1.35e-304	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
IOFPBDMD_01640	3.46e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOFPBDMD_01642	6.23e-07	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOFPBDMD_01643	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
IOFPBDMD_01644	7.39e-229	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
IOFPBDMD_01645	3.71e-105	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IOFPBDMD_01646	2.34e-204	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
IOFPBDMD_01647	9.28e-248	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IOFPBDMD_01649	2.12e-40	-	-	-	-	-	-	-	-
IOFPBDMD_01650	6.33e-253	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
IOFPBDMD_01651	1.53e-216	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IOFPBDMD_01652	0.0	-	-	-	L	-	-	-	Transposase DDE domain
IOFPBDMD_01654	1.9e-193	-	-	-	-	-	-	-	-
IOFPBDMD_01655	7.16e-113	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOFPBDMD_01656	2.84e-207	-	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
IOFPBDMD_01657	2.66e-248	-	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
IOFPBDMD_01658	5.22e-65	-	-	-	-	-	-	-	-
IOFPBDMD_01659	3.48e-219	-	-	-	P	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
IOFPBDMD_01660	5.52e-215	-	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFPBDMD_01661	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IOFPBDMD_01662	6.2e-48	-	-	-	-	-	-	-	-
IOFPBDMD_01663	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
IOFPBDMD_01664	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K11085,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter transmembrane region
IOFPBDMD_01665	1.87e-88	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
IOFPBDMD_01666	1.04e-175	-	2.7.1.39	-	S	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Phosphotransferase enzyme family
IOFPBDMD_01667	3e-154	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
IOFPBDMD_01668	4.47e-32	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
IOFPBDMD_01670	8.61e-79	-	-	-	M	-	-	-	LysM domain
IOFPBDMD_01671	0.0	-	-	-	M	-	-	-	LysM domain
IOFPBDMD_01673	8.09e-65	lciIC	-	-	K	-	-	-	Helix-turn-helix domain
IOFPBDMD_01674	1.55e-117	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
IOFPBDMD_01675	1.29e-44	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
IOFPBDMD_01677	9.36e-35	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IOFPBDMD_01682	1.47e-15	-	-	-	M	-	-	-	LysM domain
IOFPBDMD_01683	1.85e-67	-	-	-	-	-	-	-	-
IOFPBDMD_01684	9.19e-96	-	-	-	K	-	-	-	Putative DNA-binding domain
IOFPBDMD_01686	4.52e-54	-	-	-	S	-	-	-	Abortive infection C-terminus
IOFPBDMD_01687	6.15e-201	-	-	-	L	-	-	-	Phage integrase family
IOFPBDMD_01688	3.58e-16	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
IOFPBDMD_01689	1.97e-97	-	-	-	K	ko:K07467	-	ko00000	Replication initiation factor
IOFPBDMD_01690	3.78e-62	-	-	-	L	-	-	-	UvrD/REP helicase N-terminal domain
IOFPBDMD_01691	9.93e-133	-	-	-	L	-	-	-	AAA domain
IOFPBDMD_01692	3.68e-189	yeeC	-	-	P	-	-	-	T5orf172
IOFPBDMD_01693	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
IOFPBDMD_01694	0.0	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
IOFPBDMD_01695	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IOFPBDMD_01696	3.82e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
IOFPBDMD_01697	4.69e-70	-	-	-	-	-	-	-	-
IOFPBDMD_01698	2.59e-55	-	-	-	-	-	-	-	-
IOFPBDMD_01699	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IOFPBDMD_01700	6.86e-108	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
IOFPBDMD_01701	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IOFPBDMD_01702	7.41e-37	-	-	-	-	-	-	-	-
IOFPBDMD_01703	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
IOFPBDMD_01704	3.98e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
IOFPBDMD_01705	9.11e-106	yjhE	-	-	S	-	-	-	Phage tail protein
IOFPBDMD_01706	1.31e-304	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IOFPBDMD_01707	1.02e-234	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
IOFPBDMD_01708	4.02e-165	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
IOFPBDMD_01709	1.69e-218	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
IOFPBDMD_01710	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOFPBDMD_01711	5.4e-174	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_01712	0.0	-	-	-	E	-	-	-	Amino Acid
IOFPBDMD_01713	4.57e-212	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
IOFPBDMD_01714	1.53e-302	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IOFPBDMD_01715	1.33e-140	nodB3	-	-	G	-	-	-	Polysaccharide deacetylase
IOFPBDMD_01716	0.0	-	-	-	M	-	-	-	Sulfatase
IOFPBDMD_01717	1.7e-221	-	-	-	S	-	-	-	EpsG family
IOFPBDMD_01718	3.25e-107	-	-	-	D	-	-	-	Capsular exopolysaccharide family
IOFPBDMD_01719	1.45e-126	ywqC	-	-	M	ko:K16554	ko05111,map05111	ko00000,ko00001,ko02000	capsule polysaccharide biosynthetic process
IOFPBDMD_01720	6.29e-314	-	-	-	S	-	-	-	polysaccharide biosynthetic process
IOFPBDMD_01721	2.61e-252	-	-	-	M	-	-	-	Glycosyl transferases group 1
IOFPBDMD_01722	5.35e-151	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IOFPBDMD_01723	1.03e-275	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
IOFPBDMD_01724	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
IOFPBDMD_01725	1.42e-224	-	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
IOFPBDMD_01726	3.19e-142	-	-	-	M	-	-	-	Acyltransferase family
IOFPBDMD_01727	8.66e-202	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
IOFPBDMD_01728	4.48e-254	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IOFPBDMD_01729	1.41e-115	-	-	-	-	-	-	-	-
IOFPBDMD_01730	0.0	cps2E	-	-	M	-	-	-	Bacterial sugar transferase
IOFPBDMD_01731	1.09e-170	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
IOFPBDMD_01732	7.75e-146	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
IOFPBDMD_01733	4.63e-225	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
IOFPBDMD_01734	7.92e-142	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOFPBDMD_01735	1.18e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOFPBDMD_01736	5.86e-189	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IOFPBDMD_01737	1.05e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_01738	1.95e-221	-	-	-	-	-	-	-	-
IOFPBDMD_01739	0.000417	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
IOFPBDMD_01740	1.93e-110	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
IOFPBDMD_01741	1.1e-13	-	-	-	-	-	-	-	-
IOFPBDMD_01742	8.86e-145	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
IOFPBDMD_01743	9.55e-88	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOFPBDMD_01744	1.41e-201	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
IOFPBDMD_01745	6.53e-309	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IOFPBDMD_01746	5.22e-207	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOFPBDMD_01747	1.38e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IOFPBDMD_01748	6.3e-222	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IOFPBDMD_01749	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IOFPBDMD_01750	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IOFPBDMD_01751	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
IOFPBDMD_01752	2.99e-34	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
IOFPBDMD_01753	3.18e-196	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
IOFPBDMD_01754	1.51e-254	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IOFPBDMD_01755	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IOFPBDMD_01756	8.73e-262	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IOFPBDMD_01757	3.35e-169	-	-	-	M	-	-	-	Sortase family
IOFPBDMD_01758	2.51e-184	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOFPBDMD_01759	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
IOFPBDMD_01760	3.92e-86	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
IOFPBDMD_01761	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
IOFPBDMD_01762	2.22e-183	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
IOFPBDMD_01763	5.44e-201	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IOFPBDMD_01764	8.73e-96	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
IOFPBDMD_01765	3.44e-200	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IOFPBDMD_01766	6.87e-258	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IOFPBDMD_01767	1.81e-139	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IOFPBDMD_01768	1.25e-207	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IOFPBDMD_01769	6.49e-79	-	-	-	S	-	-	-	SPTR Capsular exopolysaccharide biosynthesis protein (Wzm)
IOFPBDMD_01770	1.52e-09	-	-	-	M	-	-	-	Glycosyl transferase 4-like
IOFPBDMD_01772	8.15e-90	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
IOFPBDMD_01773	2.03e-26	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
IOFPBDMD_01774	5.05e-46	-	-	-	M	-	-	-	Glycosyl transferases group 1
IOFPBDMD_01775	4.43e-46	-	-	-	S	-	-	-	Glycosyl transferase family 2
IOFPBDMD_01776	1.43e-106	cps2J	-	-	S	-	-	-	Polysaccharide biosynthesis protein
IOFPBDMD_01777	5.29e-146	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
IOFPBDMD_01778	3.46e-148	epsB	-	-	M	-	-	-	biosynthesis protein
IOFPBDMD_01779	1.23e-169	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
IOFPBDMD_01780	5.97e-106	ccl	-	-	S	-	-	-	QueT transporter
IOFPBDMD_01781	7.35e-160	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
IOFPBDMD_01782	8.55e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
IOFPBDMD_01783	3.39e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IOFPBDMD_01784	2.07e-149	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
IOFPBDMD_01785	2.22e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOFPBDMD_01786	2.37e-249	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOFPBDMD_01787	1.17e-224	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOFPBDMD_01788	1.15e-207	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOFPBDMD_01789	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IOFPBDMD_01790	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOFPBDMD_01791	5.82e-130	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IOFPBDMD_01792	8.69e-167	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
IOFPBDMD_01793	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
IOFPBDMD_01794	5.69e-189	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
IOFPBDMD_01795	7.64e-131	-	-	-	-	-	-	-	-
IOFPBDMD_01796	5.35e-70	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
IOFPBDMD_01797	9.25e-271	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
IOFPBDMD_01798	9.16e-91	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
IOFPBDMD_01799	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOFPBDMD_01800	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
IOFPBDMD_01801	1.75e-172	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
IOFPBDMD_01802	5.85e-171	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
IOFPBDMD_01803	1.36e-101	-	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Helix-hairpin-helix containing domain
IOFPBDMD_01804	0.0	-	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Helix-hairpin-helix containing domain
IOFPBDMD_01805	1.36e-139	-	-	-	-	-	-	-	-
IOFPBDMD_01806	1.61e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
IOFPBDMD_01807	1.38e-185	frlD1	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
IOFPBDMD_01808	0.0	-	-	-	G	-	-	-	Phosphodiester glycosidase
IOFPBDMD_01810	0.0	hyuA	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase N-terminal region
IOFPBDMD_01811	9.89e-264	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
IOFPBDMD_01812	1.4e-282	-	-	-	F	ko:K10974	-	ko00000,ko02000	Permease for cytosine/purines, uracil, thiamine, allantoin
IOFPBDMD_01813	2.5e-155	-	-	-	-	-	-	-	-
IOFPBDMD_01814	2.67e-79	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain protein
IOFPBDMD_01815	2.01e-213	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IOFPBDMD_01816	3.16e-100	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
IOFPBDMD_01817	4.92e-268	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
IOFPBDMD_01818	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
IOFPBDMD_01819	5.8e-270	-	-	-	-	-	-	-	-
IOFPBDMD_01820	0.0	pip	-	-	V	ko:K01421	-	ko00000	domain protein
IOFPBDMD_01821	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOFPBDMD_01822	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IOFPBDMD_01823	8.54e-223	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
IOFPBDMD_01824	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
IOFPBDMD_01826	1.58e-205	-	-	-	GM	-	-	-	NmrA-like family
IOFPBDMD_01827	6.84e-298	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
IOFPBDMD_01828	1.02e-185	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
IOFPBDMD_01829	1.45e-192	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IOFPBDMD_01830	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
IOFPBDMD_01831	4.77e-100	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IOFPBDMD_01832	3.52e-78	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IOFPBDMD_01833	4.03e-283	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IOFPBDMD_01834	3.37e-163	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
IOFPBDMD_01835	4.19e-210	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
IOFPBDMD_01836	3.91e-220	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
IOFPBDMD_01837	5.61e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IOFPBDMD_01838	1.67e-222	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IOFPBDMD_01839	2.44e-99	-	-	-	K	-	-	-	Winged helix DNA-binding domain
IOFPBDMD_01840	7.93e-94	-	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
IOFPBDMD_01841	2.01e-243	-	-	-	I	-	-	-	carboxylic ester hydrolase activity
IOFPBDMD_01842	1.42e-288	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
IOFPBDMD_01843	6.3e-82	-	-	-	P	-	-	-	Rhodanese-like domain
IOFPBDMD_01844	3.16e-109	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOFPBDMD_01845	5.55e-101	-	-	-	T	-	-	-	diguanylate cyclase activity
IOFPBDMD_01846	3.4e-257	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
IOFPBDMD_01847	2.24e-228	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
IOFPBDMD_01848	3.07e-99	-	-	-	S	-	-	-	Protein conserved in bacteria
IOFPBDMD_01849	9.57e-78	-	-	-	-	-	-	-	-
IOFPBDMD_01850	6.57e-100	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IOFPBDMD_01851	6.21e-69	-	-	-	T	-	-	-	diguanylate cyclase
IOFPBDMD_01852	8.04e-205	nox	-	-	C	-	-	-	NADH oxidase
IOFPBDMD_01853	2.87e-92	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
IOFPBDMD_01854	9.17e-37	-	-	-	-	-	-	-	-
IOFPBDMD_01855	3.31e-89	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	MarR family
IOFPBDMD_01856	2.95e-13	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
IOFPBDMD_01857	7.01e-209	-	-	-	S	-	-	-	Putative esterase
IOFPBDMD_01858	3.44e-236	-	-	-	-	-	-	-	-
IOFPBDMD_01859	2.64e-134	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
IOFPBDMD_01860	1.63e-109	-	-	-	F	-	-	-	NUDIX domain
IOFPBDMD_01861	1.15e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IOFPBDMD_01862	1.39e-40	-	-	-	-	-	-	-	-
IOFPBDMD_01863	1.17e-193	-	-	-	S	-	-	-	zinc-ribbon domain
IOFPBDMD_01864	3.38e-252	pbpX	-	-	V	-	-	-	Beta-lactamase
IOFPBDMD_01865	1.77e-239	ydbI	-	-	K	-	-	-	AI-2E family transporter
IOFPBDMD_01866	2.05e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IOFPBDMD_01867	3.45e-86	gtcA2	-	-	S	-	-	-	Teichoic acid glycosylation protein
IOFPBDMD_01868	0.0	-	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IOFPBDMD_01869	1.17e-217	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
IOFPBDMD_01870	3.51e-190	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
IOFPBDMD_01871	4.36e-283	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
IOFPBDMD_01872	2.9e-169	sfsA	-	-	S	ko:K06206	-	ko00000	Belongs to the SfsA family
IOFPBDMD_01873	7.15e-94	usp1	-	-	T	-	-	-	Universal stress protein family
IOFPBDMD_01874	9.92e-317	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
IOFPBDMD_01875	3.54e-199	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IOFPBDMD_01876	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
IOFPBDMD_01877	7.93e-291	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
IOFPBDMD_01878	0.0	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IOFPBDMD_01879	4.95e-286	floL	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	SPFH domain / Band 7 family
IOFPBDMD_01880	6.68e-89	-	-	-	-	-	-	-	-
IOFPBDMD_01881	1.16e-211	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
IOFPBDMD_01882	6.32e-228	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOFPBDMD_01883	6.61e-277	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IOFPBDMD_01884	3.3e-162	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
IOFPBDMD_01885	1.06e-185	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IOFPBDMD_01886	2.96e-132	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOFPBDMD_01887	2.91e-223	-	-	-	V	ko:K01421	-	ko00000	domain protein
IOFPBDMD_01888	4.41e-220	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOFPBDMD_01889	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IOFPBDMD_01890	2.44e-06	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IOFPBDMD_01891	4.35e-263	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IOFPBDMD_01892	1.76e-205	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
IOFPBDMD_01893	4.43e-224	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IOFPBDMD_01894	1.35e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOFPBDMD_01895	1.04e-213	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOFPBDMD_01896	1.39e-278	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IOFPBDMD_01897	1.13e-84	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
IOFPBDMD_01898	7.25e-206	CcmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOFPBDMD_01899	6.91e-149	-	-	-	I	-	-	-	ABC-2 family transporter protein
IOFPBDMD_01900	1.69e-186	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
IOFPBDMD_01901	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOFPBDMD_01902	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOFPBDMD_01903	1.99e-204	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
IOFPBDMD_01904	0.0	msbA9	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
IOFPBDMD_01905	0.0	cydD1	-	-	CO	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
IOFPBDMD_01906	6.36e-98	-	-	-	S	-	-	-	NusG domain II
IOFPBDMD_01907	1.77e-227	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
IOFPBDMD_01909	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IOFPBDMD_01910	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IOFPBDMD_01911	4.14e-232	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
IOFPBDMD_01912	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
IOFPBDMD_01913	3.89e-302	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
IOFPBDMD_01914	8.01e-231	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IOFPBDMD_01915	3.38e-50	-	-	-	-	-	-	-	-
IOFPBDMD_01916	5.18e-114	-	-	-	-	-	-	-	-
IOFPBDMD_01917	1.57e-34	-	-	-	-	-	-	-	-
IOFPBDMD_01918	5.69e-207	-	-	-	EG	-	-	-	EamA-like transporter family
IOFPBDMD_01919	2.08e-145	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
IOFPBDMD_01920	1.94e-100	usp5	-	-	T	-	-	-	universal stress protein
IOFPBDMD_01921	8.34e-86	-	-	-	K	-	-	-	Helix-turn-helix domain
IOFPBDMD_01922	4.49e-187	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IOFPBDMD_01923	5.06e-282	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
IOFPBDMD_01924	2.11e-82	-	-	-	-	-	-	-	-
IOFPBDMD_01925	2.46e-114	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
IOFPBDMD_01927	1.05e-131	-	-	-	Q	-	-	-	methyltransferase
IOFPBDMD_01928	3.75e-142	-	-	-	T	-	-	-	Sh3 type 3 domain protein
IOFPBDMD_01929	1.71e-145	-	-	-	F	-	-	-	glutamine amidotransferase
IOFPBDMD_01930	1.82e-175	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
IOFPBDMD_01931	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
IOFPBDMD_01932	2.21e-184	-	-	-	S	-	-	-	Alpha beta hydrolase
IOFPBDMD_01933	3.95e-253	-	-	-	I	-	-	-	Acyltransferase
IOFPBDMD_01934	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
IOFPBDMD_01935	9.24e-109	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
IOFPBDMD_01936	1.43e-123	maf	-	-	D	ko:K06287	-	ko00000	nucleoside-triphosphate diphosphatase activity
IOFPBDMD_01937	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IOFPBDMD_01938	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IOFPBDMD_01939	0.0	ydaO	-	-	E	-	-	-	amino acid
IOFPBDMD_01940	7.56e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF1827)
IOFPBDMD_01941	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IOFPBDMD_01942	1.7e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IOFPBDMD_01943	1.23e-142	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IOFPBDMD_01944	4.11e-251	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IOFPBDMD_01945	3.97e-235	-	-	-	-	-	-	-	-
IOFPBDMD_01946	4e-202	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOFPBDMD_01947	7.06e-81	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
IOFPBDMD_01948	7.76e-152	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IOFPBDMD_01949	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
IOFPBDMD_01950	6.92e-66	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOFPBDMD_01951	4.36e-240	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IOFPBDMD_01952	1.06e-127	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
IOFPBDMD_01953	3.82e-168	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
IOFPBDMD_01954	7.32e-153	-	-	-	-	-	-	-	-
IOFPBDMD_01955	4.02e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
IOFPBDMD_01956	8.71e-232	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
IOFPBDMD_01957	4.51e-184	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
IOFPBDMD_01958	1.56e-194	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IOFPBDMD_01959	2.27e-75	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
IOFPBDMD_01960	2.38e-225	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IOFPBDMD_01961	2.31e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
IOFPBDMD_01962	2.6e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IOFPBDMD_01963	1.35e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
IOFPBDMD_01964	2.17e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IOFPBDMD_01965	2.29e-50	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IOFPBDMD_01966	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOFPBDMD_01967	5.13e-113	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IOFPBDMD_01968	5.69e-65	-	-	-	-	-	-	-	-
IOFPBDMD_01969	3.34e-139	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
IOFPBDMD_01970	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IOFPBDMD_01971	2.27e-89	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
IOFPBDMD_01972	4.27e-162	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
IOFPBDMD_01974	4.01e-44	-	-	-	-	-	-	-	-
IOFPBDMD_01975	4.31e-97	-	-	-	L	-	-	-	Resolvase, N-terminal
IOFPBDMD_01976	2.19e-136	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
IOFPBDMD_01977	8.1e-262	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
IOFPBDMD_01978	1.04e-64	yczG	-	-	K	-	-	-	Helix-turn-helix domain
IOFPBDMD_01979	1.52e-39	-	-	-	-	-	-	-	-
IOFPBDMD_01980	1.27e-37	-	-	-	L	-	-	-	RelB antitoxin
IOFPBDMD_01981	0.0	-	-	-	L	-	-	-	Exonuclease
IOFPBDMD_01985	2.52e-16	-	-	-	-	-	-	-	-
IOFPBDMD_01986	1.75e-100	-	-	-	O	-	-	-	OsmC-like protein
IOFPBDMD_01987	2.84e-240	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
IOFPBDMD_01988	1.42e-133	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
IOFPBDMD_01989	1.22e-77	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
IOFPBDMD_01990	1.18e-134	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOFPBDMD_01991	1.61e-24	-	-	-	-	-	-	-	-
IOFPBDMD_01992	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
IOFPBDMD_01993	2.77e-222	-	-	-	-	-	-	-	-
IOFPBDMD_01994	9.29e-250	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
IOFPBDMD_01995	2.12e-192	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IOFPBDMD_02000	1.35e-174	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
IOFPBDMD_02001	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IOFPBDMD_02002	5.03e-80	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
IOFPBDMD_02003	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
IOFPBDMD_02004	3.49e-185	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
IOFPBDMD_02005	2.05e-165	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
IOFPBDMD_02006	8.14e-98	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IOFPBDMD_02007	1.8e-209	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
IOFPBDMD_02008	8.23e-61	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
IOFPBDMD_02009	2.15e-193	-	-	-	S	-	-	-	hydrolase
IOFPBDMD_02010	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
IOFPBDMD_02011	7.08e-154	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_02012	1.56e-235	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IOFPBDMD_02013	2.54e-112	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOFPBDMD_02014	1.98e-186	-	-	-	M	-	-	-	hydrolase, family 25
IOFPBDMD_02015	4.39e-25	-	-	-	S	-	-	-	YvrJ protein family
IOFPBDMD_02017	1.48e-163	-	-	-	-	-	-	-	-
IOFPBDMD_02018	1.84e-73	-	-	-	C	-	-	-	nitroreductase
IOFPBDMD_02019	1.74e-15	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
IOFPBDMD_02020	8.41e-244	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOFPBDMD_02021	2.4e-92	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
IOFPBDMD_02022	1.67e-109	-	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
IOFPBDMD_02023	3.51e-233	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
IOFPBDMD_02024	3.78e-42	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOFPBDMD_02025	9.29e-58	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOFPBDMD_02026	8.9e-83	kdsD	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
IOFPBDMD_02027	8.71e-271	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOFPBDMD_02028	7.61e-240	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
IOFPBDMD_02029	0.0	pts31BC	-	-	G	ko:K11202,ko:K11203	-	ko00000,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOFPBDMD_02030	2.4e-80	-	-	-	G	ko:K11201	-	ko00000,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOFPBDMD_02031	4.07e-24	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
IOFPBDMD_02032	2.64e-218	-	3.2.1.122, 3.2.1.86	GH4,GT4	G	ko:K01222,ko:K01232	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
IOFPBDMD_02033	8.16e-108	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
IOFPBDMD_02034	4.05e-258	-	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
IOFPBDMD_02035	2.92e-248	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
IOFPBDMD_02036	5.1e-144	-	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Pfam:DUF1498
IOFPBDMD_02037	3.92e-159	-	-	-	G	-	-	-	Domain of unknown function (DUF4432)
IOFPBDMD_02038	9.7e-211	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
IOFPBDMD_02039	4.75e-58	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOFPBDMD_02040	9.91e-87	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOFPBDMD_02041	2.17e-215	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
IOFPBDMD_02042	4.54e-40	ptsN	2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
IOFPBDMD_02043	8.13e-294	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
IOFPBDMD_02044	6.59e-291	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOFPBDMD_02045	3.04e-293	bglP11	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
IOFPBDMD_02046	1.74e-116	-	-	-	K	ko:K03488	-	ko00000,ko03000	antiterminator
IOFPBDMD_02047	3.75e-65	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
IOFPBDMD_02048	1.01e-56	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IOFPBDMD_02049	1.91e-11	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
IOFPBDMD_02051	8.14e-48	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
IOFPBDMD_02052	1.25e-263	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
IOFPBDMD_02053	4.21e-277	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
IOFPBDMD_02054	1.66e-84	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IOFPBDMD_02055	1.54e-166	-	-	-	S	-	-	-	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
IOFPBDMD_02056	4.79e-35	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IOFPBDMD_02057	3.85e-230	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
IOFPBDMD_02058	8e-41	ulaC	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOFPBDMD_02059	2.26e-72	gntR	-	-	K	-	-	-	rpiR family
IOFPBDMD_02060	2.12e-65	-	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IOFPBDMD_02061	1.62e-81	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
IOFPBDMD_02062	4.95e-39	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOFPBDMD_02063	1.47e-08	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOFPBDMD_02064	2.02e-236	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	iic component
IOFPBDMD_02066	1.88e-123	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
IOFPBDMD_02067	0.0	frdC	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	HI0933-like protein
IOFPBDMD_02068	1.09e-296	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IOFPBDMD_02069	3.54e-57	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IOFPBDMD_02070	4.15e-312	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
IOFPBDMD_02071	6.08e-192	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
IOFPBDMD_02072	1.02e-188	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
IOFPBDMD_02073	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding cassette cobalt transporter
IOFPBDMD_02074	1.43e-125	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
IOFPBDMD_02075	2.63e-203	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
IOFPBDMD_02076	3.95e-138	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
IOFPBDMD_02077	3.7e-217	-	-	-	C	-	-	-	FAD dependent oxidoreductase
IOFPBDMD_02078	7.42e-303	sdcS	-	-	P	ko:K14445	-	ko00000,ko02000	transporter
IOFPBDMD_02079	1.12e-189	kbaY	4.1.2.13, 4.1.2.40	-	G	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
IOFPBDMD_02080	5.62e-191	manZ	-	-	G	ko:K02796,ko:K02815	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
IOFPBDMD_02081	1.64e-176	-	-	-	U	ko:K02746,ko:K02795,ko:K02814	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
IOFPBDMD_02082	1.65e-102	-	2.7.1.206	-	G	ko:K02813	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IOFPBDMD_02083	2.14e-81	-	2.7.1.206	-	G	ko:K02812	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
IOFPBDMD_02084	6.9e-168	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
IOFPBDMD_02085	2.81e-209	-	-	-	K	-	-	-	sugar-binding domain protein
IOFPBDMD_02086	8.47e-304	-	-	-	E	ko:K19956	ko00051,map00051	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
IOFPBDMD_02087	0.0	-	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOFPBDMD_02088	2.62e-198	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
IOFPBDMD_02089	0.0	-	-	-	K	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOFPBDMD_02090	1.77e-198	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
IOFPBDMD_02091	7.36e-159	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
IOFPBDMD_02092	1.96e-117	fabG10	1.1.1.100, 1.3.1.28	-	IQ	ko:K00059,ko:K00216	ko00061,ko00333,ko00780,ko01040,ko01053,ko01100,ko01110,ko01130,ko01212,map00061,map00333,map00780,map01040,map01053,map01100,map01110,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
IOFPBDMD_02093	4.02e-223	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
IOFPBDMD_02094	8.81e-49	-	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IOFPBDMD_02095	6.49e-111	-	-	-	G	-	-	-	DeoC/LacD family aldolase
IOFPBDMD_02096	7.44e-153	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
IOFPBDMD_02098	3.88e-271	dcuC	-	-	C	ko:K03326	-	ko00000,ko02000	Tripartite ATP-independent periplasmic transporter, DctM component
IOFPBDMD_02099	7.6e-199	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
IOFPBDMD_02100	1.1e-112	-	-	-	S	-	-	-	Zeta toxin
IOFPBDMD_02101	6.56e-192	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
IOFPBDMD_02102	4.79e-63	-	-	-	-	-	-	-	-
IOFPBDMD_02103	4.22e-287	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
IOFPBDMD_02104	1.27e-61	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOFPBDMD_02105	8.81e-204	-	-	-	GKT	-	-	-	transcriptional antiterminator
IOFPBDMD_02106	4.94e-40	-	-	-	-	-	-	-	-
IOFPBDMD_02107	7.11e-135	-	-	-	-	-	-	-	-
IOFPBDMD_02108	2.77e-89	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOFPBDMD_02109	1.78e-152	-	-	-	EGP	-	-	-	Major Facilitator
IOFPBDMD_02110	4.33e-98	-	-	-	EGP	-	-	-	Major Facilitator
IOFPBDMD_02111	5.52e-121	-	-	-	-	-	-	-	-
IOFPBDMD_02112	7.7e-79	-	-	-	-	-	-	-	-
IOFPBDMD_02113	2.61e-90	-	-	-	-	-	-	-	-
IOFPBDMD_02114	9.81e-111	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IOFPBDMD_02115	3.66e-67	-	-	-	-	-	-	-	-
IOFPBDMD_02116	0.0	pbpC	-	-	M	ko:K21467	-	ko00000,ko01011	NTF2-like N-terminal transpeptidase domain
IOFPBDMD_02117	8.27e-183	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
IOFPBDMD_02122	7.37e-48	-	-	-	-	-	-	-	-
IOFPBDMD_02123	3.31e-58	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
IOFPBDMD_02124	2.71e-209	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IOFPBDMD_02125	1.13e-204	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
IOFPBDMD_02126	2.36e-205	rbsC	-	-	U	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IOFPBDMD_02127	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IOFPBDMD_02128	2.78e-80	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IOFPBDMD_02129	1.16e-239	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
IOFPBDMD_02130	0.0	-	-	-	E	-	-	-	Amino acid permease
IOFPBDMD_02131	4.28e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IOFPBDMD_02132	5.6e-132	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IOFPBDMD_02133	1.14e-193	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IOFPBDMD_02134	1.46e-106	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
IOFPBDMD_02135	5.44e-163	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IOFPBDMD_02136	1.33e-142	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
IOFPBDMD_02137	1.33e-311	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IOFPBDMD_02138	4.57e-123	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IOFPBDMD_02139	1.11e-49	-	-	-	-	-	-	-	-
IOFPBDMD_02140	3.48e-245	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
IOFPBDMD_02141	2.6e-150	-	-	-	S	ko:K07118	-	ko00000	NmrA-like family
IOFPBDMD_02143	8.01e-254	-	-	-	-	-	-	-	-
IOFPBDMD_02144	3.18e-195	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IOFPBDMD_02145	1.34e-115	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
IOFPBDMD_02147	1.22e-155	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
IOFPBDMD_02148	5.27e-191	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IOFPBDMD_02149	3.38e-266	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
IOFPBDMD_02150	5.22e-112	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IOFPBDMD_02151	2.94e-14	-	-	-	-	-	-	-	-
IOFPBDMD_02152	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
IOFPBDMD_02153	4.96e-270	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IOFPBDMD_02154	2.07e-147	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
IOFPBDMD_02155	2.49e-182	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
IOFPBDMD_02156	6.59e-96	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
IOFPBDMD_02157	1.85e-121	lacB	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
IOFPBDMD_02158	1.2e-238	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
IOFPBDMD_02159	1.43e-224	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
IOFPBDMD_02160	3.84e-161	-	-	-	S	-	-	-	Domain of unknown function (DUF4867)
IOFPBDMD_02161	8.15e-241	-	-	-	V	-	-	-	Beta-lactamase
IOFPBDMD_02162	1.91e-38	-	-	-	-	-	-	-	-
IOFPBDMD_02164	0.0	gatC	-	-	G	ko:K20114	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
IOFPBDMD_02165	2.13e-64	-	2.7.1.204	-	G	ko:K20113	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOFPBDMD_02166	4.46e-91	-	2.7.1.204	-	G	ko:K20112	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOFPBDMD_02168	5.59e-250	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
IOFPBDMD_02169	5.88e-213	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IOFPBDMD_02170	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
IOFPBDMD_02171	1.04e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IOFPBDMD_02172	2.83e-283	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IOFPBDMD_02174	8.62e-66	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
IOFPBDMD_02175	1.33e-311	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOFPBDMD_02176	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
IOFPBDMD_02177	5.46e-178	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	PRD domain
IOFPBDMD_02178	1.76e-174	epsG	-	-	M	-	-	-	Glycosyltransferase like family 2
IOFPBDMD_02179	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IOFPBDMD_02180	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
IOFPBDMD_02181	8.08e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IOFPBDMD_02182	8.94e-146	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
IOFPBDMD_02183	0.0	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
IOFPBDMD_02184	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
IOFPBDMD_02185	2.68e-15	-	-	-	-	-	-	-	-
IOFPBDMD_02187	2.15e-195	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
IOFPBDMD_02188	3.15e-153	yqgG	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
IOFPBDMD_02189	1.62e-226	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
IOFPBDMD_02190	1.09e-310	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
IOFPBDMD_02191	1.23e-200	-	-	-	C	-	-	-	nadph quinone reductase
IOFPBDMD_02192	1.72e-120	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NUDIX domain
IOFPBDMD_02193	1.06e-69	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
IOFPBDMD_02194	3.41e-144	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
IOFPBDMD_02195	5.46e-187	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IOFPBDMD_02196	7.73e-201	-	-	-	V	ko:K01990,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOFPBDMD_02197	5.16e-190	-	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
IOFPBDMD_02198	1.51e-89	-	-	-	K	-	-	-	LytTr DNA-binding domain
IOFPBDMD_02199	7.8e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
IOFPBDMD_02200	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
IOFPBDMD_02201	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
IOFPBDMD_02202	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
IOFPBDMD_02203	1.02e-203	-	-	-	S	-	-	-	Aldo/keto reductase family
IOFPBDMD_02204	1.11e-146	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
IOFPBDMD_02205	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
IOFPBDMD_02206	1.95e-99	-	-	-	O	-	-	-	OsmC-like protein
IOFPBDMD_02207	3.02e-92	-	-	-	-	-	-	-	-
IOFPBDMD_02208	3.08e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
IOFPBDMD_02209	1.19e-314	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IOFPBDMD_02210	3.78e-220	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
IOFPBDMD_02211	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
IOFPBDMD_02212	4.39e-273	sstT	-	-	U	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IOFPBDMD_02213	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOFPBDMD_02214	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IOFPBDMD_02215	3.66e-165	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
IOFPBDMD_02216	2.07e-281	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
IOFPBDMD_02217	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOFPBDMD_02218	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_02219	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IOFPBDMD_02220	5.32e-209	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
IOFPBDMD_02221	3.96e-187	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
IOFPBDMD_02222	2.58e-101	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
IOFPBDMD_02223	7.71e-185	CcmA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOFPBDMD_02224	0.0	-	-	-	-	-	-	-	-
IOFPBDMD_02225	1.21e-211	yicL	-	-	EG	-	-	-	EamA-like transporter family
IOFPBDMD_02226	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
IOFPBDMD_02227	6.79e-152	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
IOFPBDMD_02228	2.63e-73	-	-	-	-	-	-	-	-
IOFPBDMD_02229	3.52e-163	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
IOFPBDMD_02231	6.7e-304	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
IOFPBDMD_02232	3.8e-61	-	-	-	-	-	-	-	-
IOFPBDMD_02233	1.18e-228	-	-	-	S	-	-	-	Cell surface protein
IOFPBDMD_02234	3.31e-98	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
IOFPBDMD_02235	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IOFPBDMD_02236	2.12e-173	-	-	-	-	-	-	-	-
IOFPBDMD_02237	9.6e-156	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOFPBDMD_02238	1.61e-184	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
IOFPBDMD_02239	3.92e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IOFPBDMD_02241	2.58e-179	-	-	-	-	-	-	-	-
IOFPBDMD_02243	1.27e-221	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IOFPBDMD_02244	9.58e-209	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
IOFPBDMD_02245	4.03e-104	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
IOFPBDMD_02246	2.09e-302	xylP	-	-	G	-	-	-	MFS/sugar transport protein
IOFPBDMD_02247	0.0	ycaM	-	-	E	-	-	-	amino acid
IOFPBDMD_02248	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
IOFPBDMD_02249	8.65e-136	-	-	-	-	-	-	-	-
IOFPBDMD_02250	1.81e-252	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
IOFPBDMD_02251	8.79e-208	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
IOFPBDMD_02252	7.75e-258	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IOFPBDMD_02253	1.98e-163	-	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
IOFPBDMD_02254	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IOFPBDMD_02255	2.47e-166	XK27_12140	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOFPBDMD_02256	1e-251	-	-	-	-	-	-	-	-
IOFPBDMD_02257	2.64e-164	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IOFPBDMD_02258	9.54e-78	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
IOFPBDMD_02259	4.95e-246	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
IOFPBDMD_02260	1.52e-207	-	-	-	S	-	-	-	reductase
IOFPBDMD_02261	1.82e-97	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IOFPBDMD_02262	6.46e-290	-	-	-	E	-	-	-	Amino acid permease
IOFPBDMD_02263	5.06e-282	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
IOFPBDMD_02264	0.0	-	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamine synthetase N-terminal domain
IOFPBDMD_02265	2.96e-101	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOFPBDMD_02266	6.71e-135	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
IOFPBDMD_02267	3.54e-180	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
IOFPBDMD_02268	1.29e-177	-	-	-	H	-	-	-	Protein of unknown function (DUF1698)
IOFPBDMD_02269	2.26e-245	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
IOFPBDMD_02270	1.69e-192	pbpE	-	-	V	-	-	-	Beta-lactamase
IOFPBDMD_02271	5.86e-61	-	-	-	-	-	-	-	-
IOFPBDMD_02272	0.0	cidC	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IOFPBDMD_02273	7.61e-215	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
IOFPBDMD_02274	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
IOFPBDMD_02275	4.97e-272	-	-	-	M	-	-	-	Glycosyl transferases group 1
IOFPBDMD_02276	0.0	yebA	-	-	E	-	-	-	Transglutaminase/protease-like homologues
IOFPBDMD_02277	2.5e-172	-	-	-	S	-	-	-	Protein of unknown function DUF58
IOFPBDMD_02278	8.18e-215	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
IOFPBDMD_02279	3.53e-134	-	-	-	S	ko:K06384	-	ko00000	Stage II sporulation protein M
IOFPBDMD_02280	1.33e-128	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IOFPBDMD_02281	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOFPBDMD_02282	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOFPBDMD_02283	7.69e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_02284	7.03e-213	-	-	-	G	-	-	-	Phosphotransferase enzyme family
IOFPBDMD_02285	8.69e-183	-	-	-	S	-	-	-	AAA ATPase domain
IOFPBDMD_02286	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
IOFPBDMD_02287	1.9e-104	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
IOFPBDMD_02288	9.87e-70	-	-	-	-	-	-	-	-
IOFPBDMD_02289	7.92e-76	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
IOFPBDMD_02290	1.89e-167	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
IOFPBDMD_02291	3.97e-23	-	-	-	-	-	-	-	-
IOFPBDMD_02292	3.33e-303	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOFPBDMD_02293	7.62e-53	-	-	-	-	-	-	-	-
IOFPBDMD_02294	1.89e-172	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_02295	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOFPBDMD_02296	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
IOFPBDMD_02301	5.07e-203	-	-	-	K	-	-	-	sequence-specific DNA binding
IOFPBDMD_02302	3.25e-190	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOFPBDMD_02303	6.98e-241	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
IOFPBDMD_02304	1.62e-277	-	-	-	EGP	-	-	-	Major facilitator Superfamily
IOFPBDMD_02305	7.73e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IOFPBDMD_02306	6.18e-173	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
IOFPBDMD_02307	7.33e-218	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
IOFPBDMD_02308	1.54e-84	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
IOFPBDMD_02309	7.35e-221	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
IOFPBDMD_02310	3.01e-273	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
IOFPBDMD_02311	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOFPBDMD_02312	2.24e-146	ycaC	-	-	Q	-	-	-	Isochorismatase family
IOFPBDMD_02313	5.71e-116	-	-	-	S	-	-	-	AAA domain
IOFPBDMD_02314	4.22e-105	-	-	-	F	-	-	-	NUDIX domain
IOFPBDMD_02315	5.23e-140	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IOFPBDMD_02316	2.91e-72	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
IOFPBDMD_02317	2.7e-68	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOFPBDMD_02318	8.04e-168	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
IOFPBDMD_02319	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOFPBDMD_02320	3.7e-96	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
IOFPBDMD_02321	4.59e-271	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
IOFPBDMD_02322	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
IOFPBDMD_02323	3.99e-299	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
IOFPBDMD_02324	0.0	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
IOFPBDMD_02325	1.1e-159	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha/beta hydrolase family
IOFPBDMD_02326	5.24e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IOFPBDMD_02327	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOFPBDMD_02328	0.0	yycH	-	-	S	-	-	-	YycH protein
IOFPBDMD_02329	3.66e-183	yycI	-	-	S	-	-	-	YycH protein
IOFPBDMD_02330	2.72e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
IOFPBDMD_02331	1.99e-284	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
IOFPBDMD_02332	1.94e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
IOFPBDMD_02333	4.09e-99	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Hsp20/alpha crystallin family
IOFPBDMD_02334	0.0	cadA	-	-	P	-	-	-	P-type ATPase
IOFPBDMD_02335	0.0	-	-	-	S	-	-	-	Glycosyl hydrolase family 115
IOFPBDMD_02336	0.0	-	-	-	G	ko:K03292,ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
IOFPBDMD_02337	0.0	bgaR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IOFPBDMD_02338	9.87e-200	-	-	-	-	-	-	-	-
IOFPBDMD_02339	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IOFPBDMD_02340	5.64e-315	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
IOFPBDMD_02341	2.23e-134	-	-	-	-	-	-	-	-
IOFPBDMD_02342	7.69e-254	ysdE	-	-	P	-	-	-	Citrate transporter
IOFPBDMD_02343	1.18e-104	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IOFPBDMD_02344	1.33e-86	-	-	-	S	-	-	-	ASCH
IOFPBDMD_02345	1.69e-158	-	-	-	-	-	-	-	-
IOFPBDMD_02346	9.36e-111	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOFPBDMD_02347	2.78e-170	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IOFPBDMD_02348	6.78e-100	-	-	-	E	-	-	-	HAD-hyrolase-like
IOFPBDMD_02349	8.86e-103	yfbM	-	-	K	-	-	-	FR47-like protein
IOFPBDMD_02350	5.69e-140	-	-	-	S	-	-	-	alpha beta
IOFPBDMD_02351	2.09e-48	-	-	-	-	-	-	-	-
IOFPBDMD_02352	2.59e-75	-	-	-	-	-	-	-	-
IOFPBDMD_02353	1.17e-178	-	-	-	V	-	-	-	ABC transporter transmembrane region
IOFPBDMD_02354	8.78e-08	-	-	-	S	-	-	-	SpoVT / AbrB like domain
IOFPBDMD_02355	2.34e-65	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
IOFPBDMD_02356	3.29e-182	-	-	-	Q	-	-	-	Methyltransferase
IOFPBDMD_02357	1.23e-96	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IOFPBDMD_02358	3.72e-202	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
IOFPBDMD_02359	7.62e-219	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
IOFPBDMD_02360	1.76e-258	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
IOFPBDMD_02362	3.98e-172	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
IOFPBDMD_02363	5.03e-192	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
IOFPBDMD_02364	5.58e-104	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IOFPBDMD_02365	5.24e-208	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IOFPBDMD_02366	1.47e-185	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IOFPBDMD_02367	2.54e-244	-	-	-	V	-	-	-	Beta-lactamase
IOFPBDMD_02368	1.69e-186	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
IOFPBDMD_02369	7.56e-286	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IOFPBDMD_02370	9.24e-269	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
IOFPBDMD_02371	2.51e-208	-	-	-	P	ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport systems, permease components
IOFPBDMD_02372	6.89e-191	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOFPBDMD_02373	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOFPBDMD_02374	2.81e-90	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IOFPBDMD_02375	6.15e-170	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IOFPBDMD_02376	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IOFPBDMD_02377	2.68e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
IOFPBDMD_02378	2.06e-170	-	-	-	F	-	-	-	NUDIX domain
IOFPBDMD_02379	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
IOFPBDMD_02380	1.53e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
IOFPBDMD_02382	7.2e-144	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
IOFPBDMD_02383	6.25e-117	-	-	-	K	ko:K03828	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
IOFPBDMD_02384	5.24e-259	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
IOFPBDMD_02385	4.11e-273	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
IOFPBDMD_02386	2.04e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
IOFPBDMD_02387	1.68e-310	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
IOFPBDMD_02388	3.03e-230	asnA2	3.5.1.1	-	E	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
IOFPBDMD_02389	2.79e-199	-	-	-	GK	-	-	-	ROK family
IOFPBDMD_02390	5.44e-56	-	-	-	-	-	-	-	-
IOFPBDMD_02391	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IOFPBDMD_02392	2.97e-271	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Beta-lactamase superfamily domain
IOFPBDMD_02393	1.64e-103	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOFPBDMD_02394	0.0	sgaT	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
IOFPBDMD_02395	3.93e-60	sgaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOFPBDMD_02396	1.51e-147	ulaD	4.1.1.85, 4.1.2.43	-	G	ko:K03078,ko:K08093	ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
IOFPBDMD_02397	4.27e-176	-	-	-	K	-	-	-	DeoR C terminal sensor domain
IOFPBDMD_02398	2.13e-212	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
IOFPBDMD_02399	3.56e-194	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IOFPBDMD_02400	1.83e-176	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
IOFPBDMD_02401	6.82e-40	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
IOFPBDMD_02402	5.59e-33	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
IOFPBDMD_02403	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IOFPBDMD_02404	3.67e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IOFPBDMD_02405	6.19e-300	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
IOFPBDMD_02406	1.09e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
IOFPBDMD_02407	6.23e-87	-	-	-	M	-	-	-	Lysin motif
IOFPBDMD_02408	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
IOFPBDMD_02409	1.83e-231	-	-	-	S	-	-	-	Helix-turn-helix domain
IOFPBDMD_02410	4.03e-61	fer	-	-	C	ko:K05337	-	ko00000	4Fe-4S single cluster domain of Ferredoxin I
IOFPBDMD_02411	5.3e-124	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IOFPBDMD_02412	3.03e-178	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IOFPBDMD_02413	6.34e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IOFPBDMD_02414	8.93e-163	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IOFPBDMD_02415	2.81e-88	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOFPBDMD_02416	2.09e-212	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
IOFPBDMD_02417	7.26e-209	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
IOFPBDMD_02418	7.15e-94	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
IOFPBDMD_02419	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
IOFPBDMD_02420	9e-227	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IOFPBDMD_02421	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
IOFPBDMD_02422	2.92e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
IOFPBDMD_02423	2.15e-187	-	-	-	-	-	-	-	-
IOFPBDMD_02424	0.0	ycjM	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
IOFPBDMD_02425	2.41e-71	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
IOFPBDMD_02426	1.35e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IOFPBDMD_02427	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IOFPBDMD_02428	5.47e-63	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
IOFPBDMD_02429	1.28e-181	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
IOFPBDMD_02430	2.92e-232	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IOFPBDMD_02431	0.0	oatA	-	-	I	-	-	-	Acyltransferase
IOFPBDMD_02432	1.29e-297	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IOFPBDMD_02433	5.84e-172	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
IOFPBDMD_02434	1.21e-212	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IOFPBDMD_02435	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
IOFPBDMD_02436	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IOFPBDMD_02437	1.33e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_02438	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
IOFPBDMD_02439	2.34e-28	-	-	-	-	-	-	-	-
IOFPBDMD_02440	2.28e-63	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
IOFPBDMD_02441	5.12e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
IOFPBDMD_02442	5.9e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IOFPBDMD_02443	8.34e-271	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IOFPBDMD_02444	0.0	yknV	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
IOFPBDMD_02445	2.93e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IOFPBDMD_02446	1.12e-83	pcaC	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
IOFPBDMD_02447	5.06e-172	-	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
IOFPBDMD_02448	1.14e-108	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
IOFPBDMD_02449	4.73e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IOFPBDMD_02450	1.98e-205	-	-	-	S	-	-	-	Tetratricopeptide repeat
IOFPBDMD_02451	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOFPBDMD_02452	6.79e-152	-	-	-	-	-	-	-	-
IOFPBDMD_02453	2.48e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IOFPBDMD_02454	1.01e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
IOFPBDMD_02455	4.08e-247	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IOFPBDMD_02456	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
IOFPBDMD_02457	1.96e-147	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
IOFPBDMD_02458	2.04e-247	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IOFPBDMD_02459	2.96e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IOFPBDMD_02460	2.89e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
IOFPBDMD_02461	2.84e-75	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
IOFPBDMD_02462	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IOFPBDMD_02463	3.76e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IOFPBDMD_02464	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
IOFPBDMD_02465	1.06e-186	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
IOFPBDMD_02466	8.74e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
IOFPBDMD_02467	7.16e-201	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
IOFPBDMD_02468	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
IOFPBDMD_02469	6.23e-314	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IOFPBDMD_02470	1.34e-231	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
IOFPBDMD_02471	1.65e-266	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
IOFPBDMD_02472	8.12e-174	-	-	-	S	-	-	-	E1-E2 ATPase
IOFPBDMD_02473	1.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOFPBDMD_02474	1.83e-35	-	-	-	-	-	-	-	-
IOFPBDMD_02475	2.95e-96	-	-	-	-	-	-	-	-
IOFPBDMD_02477	4.07e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
IOFPBDMD_02478	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOFPBDMD_02479	2.93e-235	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
IOFPBDMD_02480	2.35e-311	-	-	-	S	-	-	-	Sterol carrier protein domain
IOFPBDMD_02481	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IOFPBDMD_02482	8.3e-150	-	-	-	S	-	-	-	repeat protein
IOFPBDMD_02483	9.46e-159	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
IOFPBDMD_02484	8.38e-278	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IOFPBDMD_02485	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
IOFPBDMD_02486	3.61e-77	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
IOFPBDMD_02487	9.79e-279	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IOFPBDMD_02488	3.94e-159	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IOFPBDMD_02489	1.36e-46	-	-	-	-	-	-	-	-
IOFPBDMD_02490	1.56e-127	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
IOFPBDMD_02491	9.37e-150	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
IOFPBDMD_02492	8.52e-268	yaaN	-	-	P	-	-	-	Toxic anion resistance protein (TelA)
IOFPBDMD_02493	0.0	ydiC1	-	-	EGP	-	-	-	Major Facilitator
IOFPBDMD_02494	6.09e-200	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
IOFPBDMD_02495	2.98e-49	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
IOFPBDMD_02496	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IOFPBDMD_02497	2.93e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA protein
IOFPBDMD_02498	1.91e-185	ylmH	-	-	S	-	-	-	S4 domain protein
IOFPBDMD_02499	6.86e-60	yggT	-	-	D	ko:K02221	-	ko00000,ko02044	integral membrane protein
IOFPBDMD_02500	5.1e-102	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IOFPBDMD_02501	2.19e-290	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IOFPBDMD_02502	6.05e-307	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IOFPBDMD_02503	4.67e-196	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IOFPBDMD_02504	3.84e-257	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IOFPBDMD_02505	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IOFPBDMD_02506	3.67e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IOFPBDMD_02507	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IOFPBDMD_02508	8.26e-80	ftsL	-	-	D	-	-	-	cell division protein FtsL
IOFPBDMD_02509	4.57e-217	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IOFPBDMD_02510	1.61e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
IOFPBDMD_02511	1.49e-70	-	-	-	-	-	-	-	-
IOFPBDMD_02512	4.32e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
IOFPBDMD_02513	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOFPBDMD_02515	1.63e-193	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IOFPBDMD_02516	1.29e-143	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
IOFPBDMD_02517	2.77e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
IOFPBDMD_02518	6.07e-182	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
IOFPBDMD_02519	1.28e-146	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IOFPBDMD_02520	2.13e-113	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
IOFPBDMD_02521	5.62e-193	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
IOFPBDMD_02522	6.84e-229	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
IOFPBDMD_02523	2.01e-151	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
IOFPBDMD_02524	1.63e-147	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
IOFPBDMD_02525	5.13e-304	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IOFPBDMD_02526	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IOFPBDMD_02527	3.97e-149	-	-	-	K	ko:K01926	-	ko00000,ko03000	CoA binding domain
IOFPBDMD_02528	1.73e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IOFPBDMD_02529	7.69e-275	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IOFPBDMD_02530	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IOFPBDMD_02531	6.83e-109	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
IOFPBDMD_02532	5.31e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IOFPBDMD_02534	0.0	-	-	-	KL	-	-	-	Helicase conserved C-terminal domain
IOFPBDMD_02535	2.45e-175	-	-	-	S	-	-	-	Domain of unknown function (DUF1998)
IOFPBDMD_02536	2.14e-164	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
IOFPBDMD_02537	1.13e-289	-	-	-	E	-	-	-	Amino acid permease
IOFPBDMD_02538	2.4e-180	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
IOFPBDMD_02539	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
IOFPBDMD_02540	3.68e-106	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOFPBDMD_02541	4.64e-188	-	-	-	-	-	-	-	-
IOFPBDMD_02542	0.0	-	-	-	-	-	-	-	-
IOFPBDMD_02543	1.83e-202	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOFPBDMD_02544	6.21e-165	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
IOFPBDMD_02545	1.62e-256	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOFPBDMD_02546	2.93e-133	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
IOFPBDMD_02547	1.04e-135	-	-	-	-	-	-	-	-
IOFPBDMD_02548	8.05e-197	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
IOFPBDMD_02549	0.0	bmr3	-	-	EGP	-	-	-	Major Facilitator
IOFPBDMD_02550	1.39e-174	-	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
IOFPBDMD_02551	3.89e-203	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
IOFPBDMD_02552	1.27e-308	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
IOFPBDMD_02553	9.14e-205	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
IOFPBDMD_02554	0.0	-	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
IOFPBDMD_02555	3.65e-171	-	-	-	K	-	-	-	DeoR C terminal sensor domain
IOFPBDMD_02556	1.7e-279	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOFPBDMD_02557	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
IOFPBDMD_02558	9.43e-73	-	-	-	-	-	-	-	-
IOFPBDMD_02559	4.92e-192	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
IOFPBDMD_02560	0.0	-	-	-	L	-	-	-	Mga helix-turn-helix domain
IOFPBDMD_02562	3.3e-240	ynjC	-	-	S	-	-	-	Cell surface protein
IOFPBDMD_02563	8.2e-177	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
IOFPBDMD_02565	0.0	-	-	-	-	-	-	-	-
IOFPBDMD_02566	9.29e-138	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IOFPBDMD_02567	4.75e-57	-	-	-	-	-	-	-	-
IOFPBDMD_02568	2.25e-239	mhqA	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOFPBDMD_02569	3.44e-70	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
IOFPBDMD_02570	0.0	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IOFPBDMD_02571	2.83e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
IOFPBDMD_02572	1.17e-75	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
IOFPBDMD_02573	9.23e-55	-	-	-	-	-	-	-	-
IOFPBDMD_02574	3.38e-169	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
IOFPBDMD_02575	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOFPBDMD_02576	0.0	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOFPBDMD_02577	3.35e-111	-	-	-	-	-	-	-	-
IOFPBDMD_02578	1.99e-69	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
IOFPBDMD_02579	4.97e-64	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOFPBDMD_02580	6.21e-241	ldhD3	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOFPBDMD_02581	6.05e-118	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
IOFPBDMD_02582	4.14e-155	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
IOFPBDMD_02583	5.65e-255	yclK	-	-	T	-	-	-	Histidine kinase
IOFPBDMD_02584	2.25e-111	-	-	-	-	-	-	-	-
IOFPBDMD_02585	7.29e-290	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOFPBDMD_02586	1.05e-143	-	-	-	-	-	-	-	-
IOFPBDMD_02587	1.06e-53	-	-	-	-	-	-	-	-
IOFPBDMD_02588	1.15e-261	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IOFPBDMD_02589	2.67e-56	-	-	-	-	-	-	-	-
IOFPBDMD_02590	2.16e-265	mccF	-	-	V	-	-	-	LD-carboxypeptidase
IOFPBDMD_02591	2e-238	yveB	-	-	I	-	-	-	PAP2 superfamily
IOFPBDMD_02592	2.48e-142	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
IOFPBDMD_02593	3.4e-64	-	-	-	-	-	-	-	-
IOFPBDMD_02594	1.43e-38	-	-	-	-	-	-	-	-
IOFPBDMD_02595	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
IOFPBDMD_02596	3.78e-131	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IOFPBDMD_02597	5.45e-154	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOFPBDMD_02598	6.52e-36	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
IOFPBDMD_02599	1.34e-193	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOFPBDMD_02600	7.11e-260	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOFPBDMD_02601	4.21e-72	cadC5	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
IOFPBDMD_02602	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
IOFPBDMD_02603	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IOFPBDMD_02604	2.94e-264	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
IOFPBDMD_02605	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IOFPBDMD_02606	9.01e-164	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_02607	8.13e-137	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
IOFPBDMD_02608	6.9e-200	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IOFPBDMD_02609	8.98e-253	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
IOFPBDMD_02610	8.75e-209	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IOFPBDMD_02611	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOFPBDMD_02612	3.05e-282	-	-	-	-	-	-	-	-
IOFPBDMD_02613	3.57e-314	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IOFPBDMD_02614	4.7e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IOFPBDMD_02615	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
IOFPBDMD_02616	3.17e-126	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_02617	4.01e-99	-	-	-	P	-	-	-	ABC-2 family transporter protein
IOFPBDMD_02618	3.71e-68	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
IOFPBDMD_02619	1.95e-78	-	-	-	K	-	-	-	Tetracyclin repressor, C-terminal all-alpha domain
IOFPBDMD_02620	2.4e-137	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
IOFPBDMD_02621	2.24e-64	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
IOFPBDMD_02623	5.16e-192	-	-	-	EG	-	-	-	EamA-like transporter family
IOFPBDMD_02624	2.62e-95	-	-	-	L	-	-	-	NUDIX domain
IOFPBDMD_02625	9.51e-81	-	-	-	-	-	-	-	-
IOFPBDMD_02626	5.83e-251	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IOFPBDMD_02627	5.72e-238	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IOFPBDMD_02628	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IOFPBDMD_02629	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IOFPBDMD_02630	1.03e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IOFPBDMD_02631	6.84e-278	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IOFPBDMD_02632	3.74e-210	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IOFPBDMD_02633	1.18e-174	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IOFPBDMD_02634	2.26e-136	-	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	dTDP-4-dehydrorhamnose 3,5-epimerase
IOFPBDMD_02636	5.06e-126	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOFPBDMD_02637	2.35e-136	-	-	-	-	-	-	-	-
IOFPBDMD_02638	1.39e-198	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type transport system involved in multi-copper enzyme maturation permease component
IOFPBDMD_02639	8.18e-151	-	-	-	-	-	-	-	-
IOFPBDMD_02640	6.02e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOFPBDMD_02641	0.0	-	-	-	EGP	-	-	-	Major Facilitator
IOFPBDMD_02643	6.58e-231	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IOFPBDMD_02644	2.09e-170	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
IOFPBDMD_02645	2.84e-136	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
IOFPBDMD_02646	7.93e-290	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IOFPBDMD_02647	2.89e-182	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IOFPBDMD_02649	5.67e-200	bglK_1	-	-	GK	-	-	-	ROK family
IOFPBDMD_02650	0.0	-	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOFPBDMD_02651	1.01e-179	-	-	-	K	-	-	-	SIS domain
IOFPBDMD_02652	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
IOFPBDMD_02653	1.99e-104	frvA	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOFPBDMD_02654	0.0	-	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02770,ko:K02794,ko:K02795	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOFPBDMD_02655	2.81e-201	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IOFPBDMD_02657	2.13e-150	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
IOFPBDMD_02658	6.78e-132	dpsB	-	-	P	-	-	-	Belongs to the Dps family
IOFPBDMD_02659	1.04e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
IOFPBDMD_02660	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
IOFPBDMD_02661	7.45e-279	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IOFPBDMD_02662	2.13e-136	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOFPBDMD_02663	1.96e-225	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IOFPBDMD_02664	1.37e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFPBDMD_02666	1.68e-191	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
IOFPBDMD_02667	1.3e-89	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
IOFPBDMD_02668	1.21e-309	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
IOFPBDMD_02669	2.75e-157	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
IOFPBDMD_02670	3.73e-137	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
IOFPBDMD_02671	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
IOFPBDMD_02673	6.27e-60	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOFPBDMD_02675	5.99e-287	comD	2.7.13.3	-	T	ko:K07706,ko:K12294	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
IOFPBDMD_02676	1.58e-170	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IOFPBDMD_02677	1.3e-59	-	-	-	S	-	-	-	Enterocin A Immunity
IOFPBDMD_02678	1.59e-30	-	-	-	-	-	-	-	-
IOFPBDMD_02682	8.4e-170	-	-	-	S	-	-	-	CAAX protease self-immunity
IOFPBDMD_02683	2.35e-91	-	-	-	K	-	-	-	Transcriptional regulator
IOFPBDMD_02684	0.0	norB	-	-	EGP	ko:K08170	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
IOFPBDMD_02685	1.05e-70	-	-	-	-	-	-	-	-
IOFPBDMD_02686	1.59e-71	-	-	-	S	-	-	-	Enterocin A Immunity
IOFPBDMD_02687	3.98e-229	ydhF	-	-	S	-	-	-	Aldo keto reductase
IOFPBDMD_02688	1.81e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOFPBDMD_02689	1.61e-274	yqiG	-	-	C	-	-	-	Oxidoreductase
IOFPBDMD_02690	5.39e-32	-	-	-	S	-	-	-	Short C-terminal domain
IOFPBDMD_02691	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IOFPBDMD_02692	2.58e-171	-	-	-	-	-	-	-	-
IOFPBDMD_02693	7.48e-25	-	-	-	-	-	-	-	-
IOFPBDMD_02694	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IOFPBDMD_02695	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
IOFPBDMD_02696	4.42e-84	-	-	-	-	-	-	-	-
IOFPBDMD_02697	1.61e-288	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOFPBDMD_02698	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
IOFPBDMD_02699	2.5e-34	-	-	-	-	-	-	-	-
IOFPBDMD_02700	2.4e-144	-	-	-	P	-	-	-	Cation efflux family
IOFPBDMD_02701	1.68e-67	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
IOFPBDMD_02702	1.55e-224	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IOFPBDMD_02703	9.44e-186	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
IOFPBDMD_02704	1.61e-168	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IOFPBDMD_02705	8.32e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOFPBDMD_02706	2.35e-215	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IOFPBDMD_02707	1.4e-152	-	-	-	GM	-	-	-	NmrA-like family
IOFPBDMD_02708	7.54e-113	-	-	-	-	-	-	-	-
IOFPBDMD_02709	5.73e-209	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IOFPBDMD_02710	2.99e-27	-	-	-	-	-	-	-	-
IOFPBDMD_02712	3.3e-70	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOFPBDMD_02713	5.96e-87	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOFPBDMD_02714	0.0	-	-	-	G	ko:K03292,ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
IOFPBDMD_02715	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase concanavalin-like domain
IOFPBDMD_02716	2.26e-218	ssuA	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
IOFPBDMD_02717	0.0	-	6.2.1.48	-	IQ	ko:K02182	-	ko00000,ko01000	AMP-binding enzyme C-terminal domain
IOFPBDMD_02718	5.68e-298	-	-	-	I	-	-	-	Acyltransferase family
IOFPBDMD_02719	5.81e-155	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOFPBDMD_02720	6.12e-190	ssuC	-	-	U	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOFPBDMD_02721	1.06e-156	-	-	-	S	-	-	-	B3/4 domain
IOFPBDMD_02723	3.92e-28	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
IOFPBDMD_02725	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IOFPBDMD_02726	0.0	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
IOFPBDMD_02727	8.8e-265	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IOFPBDMD_02728	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IOFPBDMD_02729	4.23e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IOFPBDMD_02730	2.05e-134	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOFPBDMD_02731	7.16e-236	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOFPBDMD_02732	3.01e-163	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOFPBDMD_02733	1.28e-45	-	-	-	-	-	-	-	-
IOFPBDMD_02734	3.52e-175	tipA	-	-	K	-	-	-	TipAS antibiotic-recognition domain
IOFPBDMD_02735	3.99e-178	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IOFPBDMD_02736	5.43e-185	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOFPBDMD_02737	4.3e-203	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOFPBDMD_02738	2.32e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOFPBDMD_02739	3.95e-147	-	-	-	-	-	-	-	-
IOFPBDMD_02740	2.94e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
IOFPBDMD_02741	1.8e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOFPBDMD_02742	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IOFPBDMD_02743	2.66e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IOFPBDMD_02744	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
IOFPBDMD_02745	4.15e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IOFPBDMD_02746	3.86e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IOFPBDMD_02747	1.63e-297	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IOFPBDMD_02748	1.42e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IOFPBDMD_02749	1.83e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
IOFPBDMD_02750	8.15e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IOFPBDMD_02751	5.63e-77	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IOFPBDMD_02752	3.7e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IOFPBDMD_02753	1.32e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IOFPBDMD_02754	1.23e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IOFPBDMD_02755	1.67e-66	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IOFPBDMD_02756	1.73e-77	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IOFPBDMD_02757	9.86e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IOFPBDMD_02758	4.53e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IOFPBDMD_02759	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IOFPBDMD_02760	2.92e-153	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IOFPBDMD_02761	4.5e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IOFPBDMD_02762	5.26e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IOFPBDMD_02763	2.07e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IOFPBDMD_02764	5.07e-62	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IOFPBDMD_02765	3.43e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IOFPBDMD_02766	1.4e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IOFPBDMD_02767	1.09e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IOFPBDMD_02768	1.26e-90	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
IOFPBDMD_02769	5.85e-139	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
IOFPBDMD_02770	4.99e-252	-	-	-	K	-	-	-	WYL domain
IOFPBDMD_02771	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IOFPBDMD_02772	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IOFPBDMD_02773	3.18e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IOFPBDMD_02774	0.0	-	-	-	M	-	-	-	domain protein
IOFPBDMD_02775	3.06e-44	-	-	-	M	-	-	-	domain protein
IOFPBDMD_02776	2.84e-109	-	3.4.23.43	-	-	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	-
IOFPBDMD_02777	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOFPBDMD_02778	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOFPBDMD_02779	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IOFPBDMD_02780	7.17e-104	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family