Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
KIOFINJO_00002	3.68e-172	agrA	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
KIOFINJO_00003	1.03e-301	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
KIOFINJO_00005	1.9e-203	mesE	-	-	M	ko:K20345	ko02024,map02024	ko00000,ko00001,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KIOFINJO_00006	2.57e-67	mesE	-	-	M	ko:K20345	ko02024,map02024	ko00000,ko00001,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KIOFINJO_00007	0.0	comA	-	-	V	ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KIOFINJO_00008	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
KIOFINJO_00009	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
KIOFINJO_00011	1.34e-120	XK27_09885	-	-	V	-	-	-	Glycopeptide antibiotics resistance protein
KIOFINJO_00012	1.36e-286	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KIOFINJO_00013	2.44e-139	yutD	-	-	J	-	-	-	protein conserved in bacteria
KIOFINJO_00014	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KIOFINJO_00016	2.81e-280	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KIOFINJO_00017	4.13e-11	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KIOFINJO_00018	8.08e-236	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KIOFINJO_00019	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
KIOFINJO_00020	5.53e-62	ftsL	-	-	D	-	-	-	cell division protein FtsL
KIOFINJO_00021	6.2e-197	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KIOFINJO_00022	1.25e-68	-	-	-	-	-	-	-	-
KIOFINJO_00023	1.93e-28	-	-	-	-	-	-	-	-
KIOFINJO_00024	8.59e-54	-	-	-	-	-	-	-	-
KIOFINJO_00026	4.29e-40	-	-	-	J	-	-	-	Protein of unknown function (DUF805)
KIOFINJO_00027	1.12e-28	-	-	-	D	-	-	-	nuclear chromosome segregation
KIOFINJO_00028	2.02e-76	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KIOFINJO_00029	9.26e-195	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KIOFINJO_00030	2.47e-182	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KIOFINJO_00031	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
KIOFINJO_00032	4.4e-117	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
KIOFINJO_00033	1.92e-60	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPase activity
KIOFINJO_00034	3.67e-137	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
KIOFINJO_00035	6.65e-15	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
KIOFINJO_00036	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
KIOFINJO_00037	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KIOFINJO_00038	2.54e-84	-	-	-	S	-	-	-	membrane
KIOFINJO_00039	3.34e-14	XK27_02470	-	-	K	-	-	-	LytTr DNA-binding domain protein
KIOFINJO_00040	2.08e-81	-	-	-	KT	-	-	-	response to antibiotic
KIOFINJO_00041	6.48e-22	-	-	-	KT	-	-	-	response to antibiotic
KIOFINJO_00042	2.11e-127	yebC	-	-	M	-	-	-	Membrane
KIOFINJO_00043	4.77e-24	yebC	-	-	M	-	-	-	Membrane
KIOFINJO_00044	0.0	-	-	-	S	-	-	-	hydrolases of the HAD superfamily
KIOFINJO_00045	8.08e-223	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KIOFINJO_00046	3.74e-167	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KIOFINJO_00047	1.62e-288	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KIOFINJO_00048	1.92e-243	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KIOFINJO_00049	1.75e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KIOFINJO_00050	4.1e-251	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KIOFINJO_00051	2.03e-251	aroH	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KIOFINJO_00052	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KIOFINJO_00054	6.2e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
KIOFINJO_00055	2.77e-219	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	Fructokinase
KIOFINJO_00056	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
KIOFINJO_00057	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
KIOFINJO_00058	3.37e-152	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional
KIOFINJO_00059	2.67e-96	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KIOFINJO_00060	9.01e-81	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	protein conserved in bacteria
KIOFINJO_00061	1.22e-126	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KIOFINJO_00062	1.43e-109	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
KIOFINJO_00063	5.88e-256	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Belongs to the peptidase M24B family
KIOFINJO_00066	7.27e-57	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	'abc transporter, ATP-binding protein
KIOFINJO_00067	2.97e-46	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	'abc transporter, ATP-binding protein
KIOFINJO_00070	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KIOFINJO_00071	3.96e-86	corA	-	-	P	ko:K03284	-	ko00000,ko02000	COG0598 Mg2 and Co2 transporters
KIOFINJO_00072	6.23e-91	corA	-	-	P	ko:K03284	-	ko00000,ko02000	COG0598 Mg2 and Co2 transporters
KIOFINJO_00073	5.91e-159	-	-	-	S	-	-	-	Pfam PF06570
KIOFINJO_00075	2.03e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KIOFINJO_00076	2.07e-118	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KIOFINJO_00077	3.11e-62	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
KIOFINJO_00079	3.72e-35	XK27_05745	-	-	-	-	-	-	-
KIOFINJO_00080	9.59e-293	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
KIOFINJO_00084	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KIOFINJO_00085	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KIOFINJO_00086	9.72e-121	cvpA	-	-	S	ko:K03558	-	ko00000	toxin biosynthetic process
KIOFINJO_00087	5.78e-19	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KIOFINJO_00088	1.91e-205	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KIOFINJO_00089	3.19e-146	spi	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
KIOFINJO_00090	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KIOFINJO_00091	1.91e-63	azlD	-	-	E	-	-	-	branched-chain amino acid
KIOFINJO_00092	2.76e-104	XK27_12120	-	-	E	-	-	-	AzlC protein
KIOFINJO_00093	2.1e-30	XK27_12120	-	-	E	-	-	-	AzlC protein
KIOFINJO_00094	1.64e-238	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KIOFINJO_00095	1.54e-96	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KIOFINJO_00096	2.39e-156	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214, inactive homolog of metal-dependent proteases
KIOFINJO_00097	6.45e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
KIOFINJO_00098	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KIOFINJO_00099	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
KIOFINJO_00100	1.12e-83	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
KIOFINJO_00101	1.53e-113	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
KIOFINJO_00102	1.82e-17	-	-	-	-	-	-	-	-
KIOFINJO_00103	2.31e-230	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
KIOFINJO_00105	1.54e-52	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KIOFINJO_00106	7.29e-125	ypmS	-	-	S	-	-	-	Protein conserved in bacteria
KIOFINJO_00107	1.09e-187	ypmR	-	-	E	-	-	-	lipolytic protein G-D-S-L family
KIOFINJO_00108	3.39e-190	WQ51_01275	-	-	S	-	-	-	DegV family
KIOFINJO_00109	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
KIOFINJO_00110	1.26e-96	argR	-	-	K	ko:K03402	-	ko00000,ko03000	arginine binding
KIOFINJO_00111	2.83e-203	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
KIOFINJO_00112	5.71e-204	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
KIOFINJO_00113	1.72e-40	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease VII activity
KIOFINJO_00114	1.83e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KIOFINJO_00117	3.13e-153	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KIOFINJO_00118	9.02e-163	dnaD	-	-	-	ko:K02086	-	ko00000	-
KIOFINJO_00119	6.91e-233	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KIOFINJO_00120	6.44e-122	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KIOFINJO_00121	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease recj
KIOFINJO_00122	1.56e-179	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
KIOFINJO_00123	4.43e-222	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KIOFINJO_00124	4.69e-151	XK27_05445	-	-	G	-	-	-	UDPglucose--hexose-1-phosphate uridylyltransferase
KIOFINJO_00125	4.06e-286	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KIOFINJO_00126	0.0	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
KIOFINJO_00127	1.23e-89	XK27_08080	-	-	G	-	-	-	Exopolysaccharide biosynthesis protein
KIOFINJO_00128	1.46e-17	XK27_08080	-	-	G	-	-	-	Exopolysaccharide biosynthesis protein
KIOFINJO_00129	8.05e-180	hisJ	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
KIOFINJO_00130	5.08e-158	-	-	-	S	-	-	-	tigr01906
KIOFINJO_00131	8.04e-183	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KIOFINJO_00132	7.79e-185	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
KIOFINJO_00133	2.21e-275	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
KIOFINJO_00137	3.31e-264	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KIOFINJO_00138	4.07e-144	rmlC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KIOFINJO_00139	7.83e-206	rfbA	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KIOFINJO_00140	2.93e-262	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	oxidoreductase
KIOFINJO_00141	2.15e-129	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	Mediates zinc uptake. May also transport other divalent cations
KIOFINJO_00142	3.75e-29	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	Mediates zinc uptake. May also transport other divalent cations
KIOFINJO_00143	1.15e-189	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KIOFINJO_00144	1e-70	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
KIOFINJO_00145	1.3e-77	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
KIOFINJO_00146	1.66e-91	mesH	-	-	S	-	-	-	GtrA-like protein
KIOFINJO_00147	4.62e-316	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KIOFINJO_00148	1.47e-217	ybbR	-	-	S	-	-	-	Protein conserved in bacteria
KIOFINJO_00149	1.15e-160	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KIOFINJO_00150	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain protein
KIOFINJO_00151	1.02e-192	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
KIOFINJO_00152	6.21e-119	mprF	2.3.2.3	-	J	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KIOFINJO_00153	0.0	mprF	2.3.2.3	-	J	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KIOFINJO_00154	4.3e-169	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha beta hydrolase
KIOFINJO_00155	1.84e-186	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	abc transporter atp-binding protein
KIOFINJO_00156	1.82e-240	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	abc transporter atp-binding protein
KIOFINJO_00157	2.24e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
KIOFINJO_00158	9.56e-245	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
KIOFINJO_00159	5.52e-18	-	6.3.2.2, 6.3.2.4	-	F	ko:K01919,ko:K01921	ko00270,ko00473,ko00480,ko00550,ko01100,ko01502,map00270,map00473,map00480,map00550,map01100,map01502	ko00000,ko00001,ko00002,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
KIOFINJO_00160	0.0	gapN	1.2.1.9	-	C	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
KIOFINJO_00161	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KIOFINJO_00162	1.58e-50	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein Hpr
KIOFINJO_00163	4.36e-284	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate dehydrogenase
KIOFINJO_00164	4.25e-271	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
KIOFINJO_00165	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KIOFINJO_00166	3.36e-46	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
KIOFINJO_00167	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KIOFINJO_00168	8.44e-237	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KIOFINJO_00170	3.68e-97	-	-	-	L	-	-	-	Transposase (IS116 IS110 IS902 family)
KIOFINJO_00171	2.7e-86	-	-	-	L	-	-	-	Transposase (IS116 IS110 IS902 family)
KIOFINJO_00172	5.92e-213	ypuA	-	-	S	-	-	-	secreted protein
KIOFINJO_00173	1.48e-73	ywkD	-	-	E	ko:K08234	-	ko00000	COG0346 LactoylglutaTHIone lyase and related lyases
KIOFINJO_00174	3.97e-76	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
KIOFINJO_00175	1.12e-78	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase (surface protein transpeptidase)
KIOFINJO_00176	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KIOFINJO_00177	6.05e-144	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KIOFINJO_00178	2.06e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
KIOFINJO_00179	0.0	noxE	-	-	P	-	-	-	NADH oxidase
KIOFINJO_00180	0.0	yheS_1	-	-	S	-	-	-	abc transporter atp-binding protein
KIOFINJO_00181	7.55e-61	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
KIOFINJO_00182	5.36e-12	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
KIOFINJO_00183	7.8e-198	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Belongs to the pyridoxine kinase family
KIOFINJO_00184	1.46e-112	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
KIOFINJO_00186	1.21e-303	ycxD	-	-	K	-	-	-	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KIOFINJO_00187	4.59e-75	nrdD_1	1.1.98.6, 1.17.4.1	-	F	ko:K00525,ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleoside-triphosphate reductase
KIOFINJO_00190	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KIOFINJO_00191	2.52e-119	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KIOFINJO_00192	1.75e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KIOFINJO_00193	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
KIOFINJO_00194	1.5e-116	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
KIOFINJO_00195	6.47e-161	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KIOFINJO_00196	3.12e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KIOFINJO_00197	8.33e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KIOFINJO_00198	4.29e-116	alkD	-	-	L	-	-	-	Dna alkylation repair
KIOFINJO_00199	8.82e-119	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	acetyltransferase
KIOFINJO_00201	7.46e-200	-	-	-	K	ko:K20373,ko:K20374	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
KIOFINJO_00202	0.0	-	-	-	KLT	-	-	-	serine threonine protein kinase
KIOFINJO_00203	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
KIOFINJO_00204	2.51e-17	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
KIOFINJO_00205	8.05e-166	Z012_04635	-	-	K	-	-	-	sequence-specific DNA binding
KIOFINJO_00207	1.15e-296	-	-	-	C	ko:K06871	-	ko00000	Radical SAM
KIOFINJO_00208	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
KIOFINJO_00209	2.28e-207	-	-	-	L	-	-	-	Replication initiation factor
KIOFINJO_00210	1.95e-26	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
KIOFINJO_00211	8.68e-278	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
KIOFINJO_00213	3.74e-303	rarA	-	-	L	ko:K07478	-	ko00000	ATPase related to the helicase subunit of the Holliday junction resolvase
KIOFINJO_00214	1.73e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
KIOFINJO_00215	4.83e-59	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
KIOFINJO_00216	2.06e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KIOFINJO_00217	2.7e-62	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
KIOFINJO_00218	0.0	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
KIOFINJO_00219	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
KIOFINJO_00220	7.68e-20	-	-	-	-	-	-	-	-
KIOFINJO_00221	1.87e-118	-	-	-	K	-	-	-	acetyltransferase
KIOFINJO_00222	2.18e-150	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KIOFINJO_00223	9.38e-187	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
KIOFINJO_00224	5.33e-216	XK27_01785	-	-	S	-	-	-	cog cog1284
KIOFINJO_00225	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KIOFINJO_00227	4.78e-308	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
KIOFINJO_00228	3.8e-174	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
KIOFINJO_00229	2.42e-45	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
KIOFINJO_00230	4.33e-36	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
KIOFINJO_00231	1.22e-26	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
KIOFINJO_00234	3.77e-68	yegS	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	lipid kinase activity
KIOFINJO_00235	1.08e-124	-	-	-	S	-	-	-	Hydrophobic domain protein
KIOFINJO_00237	1.61e-44	ytgB	-	-	S	-	-	-	Membrane
KIOFINJO_00238	1.32e-131	-	-	-	-	-	-	-	-
KIOFINJO_00239	7.53e-33	-	-	-	S	-	-	-	Small integral membrane protein
KIOFINJO_00240	1.02e-41	-	-	-	M	-	-	-	Protein conserved in bacteria
KIOFINJO_00241	8.12e-64	-	-	-	M	-	-	-	Protein conserved in bacteria
KIOFINJO_00242	1.49e-28	-	-	-	K	-	-	-	CsbD-like
KIOFINJO_00243	9.38e-134	XK27_06885	-	-	L	-	-	-	hydrolase
KIOFINJO_00244	2.9e-18	XK27_06885	-	-	L	-	-	-	hydrolase
KIOFINJO_00245	1.3e-26	-	-	-	K	ko:K10947	-	ko00000,ko03000	negative regulation of transcription, DNA-templated
KIOFINJO_00246	7.45e-34	-	-	-	K	ko:K10947	-	ko00000,ko03000	negative regulation of transcription, DNA-templated
KIOFINJO_00247	1.17e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
KIOFINJO_00248	1e-147	-	-	-	S	-	-	-	Putative adhesin
KIOFINJO_00249	8.83e-266	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
KIOFINJO_00250	3.98e-124	XK27_06935	-	-	K	-	-	-	transcriptional regulator
KIOFINJO_00251	7.97e-73	ypaA	-	-	S	ko:K08987	-	ko00000	membrane
KIOFINJO_00252	2.05e-09	-	-	-	-	-	-	-	-
KIOFINJO_00253	5.92e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KIOFINJO_00254	3.05e-63	WQ51_01655	-	-	S	-	-	-	Biofilm formation stimulator VEG
KIOFINJO_00255	1.29e-312	dnaC	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
KIOFINJO_00256	2.86e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
KIOFINJO_00257	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
KIOFINJO_00258	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KIOFINJO_00259	1.04e-242	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KIOFINJO_00260	3e-16	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KIOFINJO_00261	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
KIOFINJO_00262	9.5e-124	isaA	-	-	M	-	-	-	Immunodominant staphylococcal antigen A
KIOFINJO_00263	1.37e-122	lytE	-	-	M	-	-	-	LysM domain protein
KIOFINJO_00264	1.26e-125	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KIOFINJO_00265	1.85e-39	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KIOFINJO_00266	2.6e-195	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KIOFINJO_00267	4.68e-196	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KIOFINJO_00268	1.55e-117	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KIOFINJO_00269	3.09e-185	ymfM	-	-	S	ko:K15539	-	ko00000	sequence-specific DNA binding
KIOFINJO_00270	2.93e-115	ymfH	-	-	S	-	-	-	Peptidase M16
KIOFINJO_00271	3.5e-126	ymfH	-	-	S	-	-	-	Peptidase M16
KIOFINJO_00272	9.12e-301	albE	-	-	S	-	-	-	Peptidase M16
KIOFINJO_00273	1.3e-57	yaaA	-	-	S	-	-	-	S4 domain protein YaaA
KIOFINJO_00274	2.24e-262	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KIOFINJO_00275	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KIOFINJO_00276	1.17e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
KIOFINJO_00277	3.96e-195	XK27_10395	-	-	S	-	-	-	membrane
KIOFINJO_00278	0.0	ykpA	-	-	S	-	-	-	abc transporter atp-binding protein
KIOFINJO_00279	2e-122	XK27_10405	-	-	S	-	-	-	Bacterial membrane protein YfhO
KIOFINJO_00280	0.0	XK27_10405	-	-	S	-	-	-	Bacterial membrane protein YfhO
KIOFINJO_00284	3.66e-155	yveI	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
KIOFINJO_00285	1.79e-111	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KIOFINJO_00286	5.34e-270	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
KIOFINJO_00287	3.94e-173	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
KIOFINJO_00288	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KIOFINJO_00289	1.57e-259	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KIOFINJO_00290	9.5e-39	yyzM	-	-	S	-	-	-	Protein conserved in bacteria
KIOFINJO_00291	1.06e-258	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KIOFINJO_00292	4.43e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KIOFINJO_00293	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KIOFINJO_00294	3.77e-53	yabO	-	-	J	-	-	-	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KIOFINJO_00295	8.2e-81	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
KIOFINJO_00296	1.94e-05	-	-	-	-	-	-	-	-
KIOFINJO_00297	3.78e-307	-	3.5.2.6	-	V	ko:K01467	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01000	Beta-lactamase enzyme family
KIOFINJO_00298	1.87e-307	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KIOFINJO_00299	2.22e-126	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
KIOFINJO_00300	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KIOFINJO_00301	3.83e-173	-	-	-	L	-	-	-	Transposase
KIOFINJO_00304	2.35e-122	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
KIOFINJO_00305	7.91e-115	treR	-	-	K	ko:K03486	-	ko00000,ko03000	trehalose operon
KIOFINJO_00306	2.66e-29	treR	-	-	K	ko:K03486,ko:K03710	-	ko00000,ko03000	DNA-binding transcription factor activity
KIOFINJO_00307	4.42e-75	treB	2.7.1.201	-	G	ko:K02817,ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS System
KIOFINJO_00308	2.49e-88	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
KIOFINJO_00309	3.27e-155	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
KIOFINJO_00310	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
KIOFINJO_00311	2.89e-87	-	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Dehydrogenase
KIOFINJO_00312	5.62e-132	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Dehydrogenase
KIOFINJO_00313	1.16e-100	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
KIOFINJO_00314	3.04e-48	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	hydroxyacid-oxoacid transhydrogenase activity
KIOFINJO_00315	7.42e-74	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
KIOFINJO_00316	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
KIOFINJO_00317	7.9e-288	norN	-	-	V	-	-	-	Mate efflux family protein
KIOFINJO_00318	1.87e-76	asp	-	-	S	-	-	-	cog cog1302
KIOFINJO_00319	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
KIOFINJO_00320	1.57e-11	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
KIOFINJO_00321	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
KIOFINJO_00322	0.0	ilvB	2.2.1.6	-	EH	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
KIOFINJO_00323	2.89e-100	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
KIOFINJO_00324	1.88e-250	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KIOFINJO_00325	1.01e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KIOFINJO_00326	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
KIOFINJO_00327	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KIOFINJO_00328	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KIOFINJO_00329	3.93e-91	-	-	-	S	-	-	-	cog cog4699
KIOFINJO_00330	1.54e-152	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KIOFINJO_00331	1.22e-251	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
KIOFINJO_00332	2.23e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
KIOFINJO_00333	1.03e-75	cglD	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	Competence protein
KIOFINJO_00334	1.28e-21	-	-	-	NU	-	-	-	Type II secretory pathway pseudopilin
KIOFINJO_00335	2.56e-94	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Competence protein ComGF
KIOFINJO_00336	5.13e-17	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
KIOFINJO_00337	2.04e-227	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
KIOFINJO_00338	4.85e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KIOFINJO_00339	1.18e-36	lanR	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
KIOFINJO_00340	9.58e-88	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
KIOFINJO_00342	3.37e-143	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
KIOFINJO_00343	1.17e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KIOFINJO_00344	6.4e-261	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
KIOFINJO_00346	3.48e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
KIOFINJO_00347	5.51e-147	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KIOFINJO_00348	2.09e-244	yeeE	-	-	S	ko:K07112	-	ko00000	Sulphur transport
KIOFINJO_00349	3.2e-49	yeeD	-	-	O	ko:K07112	-	ko00000	sulfur carrier activity
KIOFINJO_00350	2.37e-18	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KIOFINJO_00351	1.28e-49	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KIOFINJO_00352	1.7e-117	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KIOFINJO_00354	3.45e-203	rrmA	2.1.1.187	-	Q	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	methyltransferase
KIOFINJO_00355	9.2e-87	-	-	-	S	ko:K07025	-	ko00000	phosphatase activity
KIOFINJO_00356	4.52e-56	-	-	-	S	ko:K07025	-	ko00000	glycolate biosynthetic process
KIOFINJO_00357	6.92e-105	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KIOFINJO_00358	2.31e-281	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KIOFINJO_00359	4.01e-122	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KIOFINJO_00360	5.64e-153	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
KIOFINJO_00361	1.95e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
KIOFINJO_00362	7.25e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
KIOFINJO_00363	9.39e-83	XK27_08585	-	-	S	ko:K16926	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
KIOFINJO_00364	2.99e-83	nirC_1	-	-	P	-	-	-	Formate nitrite transporter
KIOFINJO_00365	7.8e-11	nirC_1	-	-	P	-	-	-	Formate nitrite transporter
KIOFINJO_00366	2.68e-171	-	-	-	S	-	-	-	PAS domain
KIOFINJO_00367	1.79e-46	XK27_09615	-	-	S	-	-	-	FMN reductase (NADPH) activity
KIOFINJO_00368	4.15e-46	XK27_09620	-	-	S	-	-	-	FMN reductase (NADPH) activity
KIOFINJO_00369	1.42e-85	XK27_09620	-	-	S	-	-	-	FMN reductase (NADPH) activity
KIOFINJO_00370	2.98e-104	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KIOFINJO_00371	4.76e-88	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KIOFINJO_00372	3.12e-162	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KIOFINJO_00373	3.23e-16	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
KIOFINJO_00374	2.42e-49	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
KIOFINJO_00375	9.62e-116	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
KIOFINJO_00376	3.28e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
KIOFINJO_00377	1.69e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KIOFINJO_00378	1.66e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KIOFINJO_00379	1.56e-98	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
KIOFINJO_00380	2.22e-108	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
KIOFINJO_00381	4.59e-209	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KIOFINJO_00382	2.92e-103	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KIOFINJO_00383	3.19e-294	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
KIOFINJO_00384	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase
KIOFINJO_00385	7.08e-74	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KIOFINJO_00386	1.8e-180	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KIOFINJO_00387	1.98e-236	jag	-	-	S	ko:K06346	-	ko00000	RNA-binding protein
KIOFINJO_00388	9.33e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
KIOFINJO_00389	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KIOFINJO_00390	3.42e-45	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
KIOFINJO_00391	1.09e-311	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KIOFINJO_00392	4.98e-48	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KIOFINJO_00393	2.52e-302	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Membrane protein involved in D-alanine export
KIOFINJO_00394	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KIOFINJO_00395	3.08e-14	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
KIOFINJO_00396	0.0	XK27_10035	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
KIOFINJO_00397	0.0	yfiB1	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
KIOFINJO_00398	3.79e-138	pvaA	-	-	M	ko:K02395	-	ko00000,ko02035	lytic transglycosylase activity
KIOFINJO_00399	1.82e-229	-	-	-	S	-	-	-	37-kD nucleoid-associated bacterial protein
KIOFINJO_00400	1.24e-298	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KIOFINJO_00401	5.72e-139	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KIOFINJO_00402	2.15e-197	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KIOFINJO_00403	5.57e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KIOFINJO_00404	1.16e-143	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
KIOFINJO_00405	1.3e-239	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KIOFINJO_00406	6.55e-196	gst	-	-	O	ko:K11209	-	ko00000,ko01000	Glutathione S-transferase
KIOFINJO_00407	4.29e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	domain protein
KIOFINJO_00408	6.83e-227	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KIOFINJO_00409	1.39e-61	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	50S ribosomal protein L31
KIOFINJO_00410	3.14e-294	mntH_2	-	-	P	-	-	-	Mn2 and Fe2 transporters of the NRAMP family
KIOFINJO_00411	1.93e-12	-	-	-	-	-	-	-	-
KIOFINJO_00412	8.24e-25	-	-	-	-	-	-	-	-
KIOFINJO_00413	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KIOFINJO_00414	1.44e-16	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KIOFINJO_00415	5.11e-187	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division protein DivIVA
KIOFINJO_00416	5.86e-185	ylmH	-	-	T	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	S4 RNA-binding domain
KIOFINJO_00417	4.42e-47	yggT	-	-	D	ko:K02221	-	ko00000,ko02044	integral membrane protein
KIOFINJO_00418	5.13e-125	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KIOFINJO_00419	1.39e-159	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KIOFINJO_00420	2.64e-303	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KIOFINJO_00421	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KIOFINJO_00422	2.43e-245	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KIOFINJO_00423	5.46e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KIOFINJO_00424	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KIOFINJO_00425	2.68e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3165)
KIOFINJO_00426	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
KIOFINJO_00427	2.49e-230	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
KIOFINJO_00428	7.8e-38	yqgQ	-	-	S	-	-	-	protein conserved in bacteria
KIOFINJO_00429	5.82e-105	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
KIOFINJO_00430	5.49e-119	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
KIOFINJO_00431	1.34e-151	pppA	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
KIOFINJO_00432	4.19e-289	-	-	-	V	-	-	-	D-alanyl-D-alanine carboxypeptidase
KIOFINJO_00433	6.73e-145	sodA	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
KIOFINJO_00434	2.71e-236	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
KIOFINJO_00435	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KIOFINJO_00436	2.18e-73	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
KIOFINJO_00437	6.06e-97	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
KIOFINJO_00438	5.7e-188	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
KIOFINJO_00439	7.6e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
KIOFINJO_00440	5.52e-240	spd	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
KIOFINJO_00441	2.12e-114	higA	-	-	K	ko:K18831	-	ko00000,ko02048,ko03000	Pfam:DUF955
KIOFINJO_00442	1.21e-124	-	-	-	-	-	-	-	-
KIOFINJO_00444	6.18e-169	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
KIOFINJO_00445	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
KIOFINJO_00446	3.25e-43	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Type I site-specific deoxyribonuclease, HsdR family
KIOFINJO_00447	1.32e-217	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Type I restriction enzyme R protein N terminus (HSDR_N)
KIOFINJO_00448	7.07e-287	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Type I site-specific deoxyribonuclease, HsdR family
KIOFINJO_00449	1.23e-123	sdh	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KIOFINJO_00450	1.92e-24	sdh	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KIOFINJO_00451	9.97e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
KIOFINJO_00452	6.94e-146	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KIOFINJO_00453	1.98e-36	-	-	-	P	-	-	-	Hemerythrin HHE cation binding domain protein
KIOFINJO_00454	6.96e-197	-	3.5.1.28	-	M	ko:K01447,ko:K07273	-	ko00000,ko01000	Glycosyl hydrolase, family 25
KIOFINJO_00455	2.49e-105	-	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KIOFINJO_00456	3.06e-151	pgm	-	-	G	-	-	-	Phosphoglycerate mutase
KIOFINJO_00457	3.26e-224	-	-	-	S	ko:K07025	-	ko00000	hydrolase
KIOFINJO_00458	5.38e-30	-	-	-	-	-	-	-	-
KIOFINJO_00459	1.16e-78	-	-	-	M	-	-	-	LysM domain
KIOFINJO_00460	7.16e-70	-	-	-	M	-	-	-	LysM domain
KIOFINJO_00461	4.12e-28	-	-	-	M	-	-	-	LysM domain
KIOFINJO_00462	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
KIOFINJO_00463	1.45e-29	-	-	-	L	-	-	-	Transposase
KIOFINJO_00464	6.62e-62	-	-	-	L	ko:K07483	-	ko00000	transposase activity
KIOFINJO_00465	7.41e-25	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KIOFINJO_00466	5.6e-271	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KIOFINJO_00467	2.73e-33	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KIOFINJO_00468	4.47e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KIOFINJO_00469	8.63e-183	cmpC	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
KIOFINJO_00470	0.0	XK27_00665	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
KIOFINJO_00471	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KIOFINJO_00472	1.28e-293	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
KIOFINJO_00473	1.29e-187	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
KIOFINJO_00474	1.76e-182	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KIOFINJO_00475	9.27e-66	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
KIOFINJO_00476	3.92e-163	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
KIOFINJO_00477	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
KIOFINJO_00478	6.79e-40	rgfB	3.1.3.90	-	L	ko:K06896	ko00500,map00500	ko00000,ko00001,ko01000	Endonuclease/Exonuclease/phosphatase family
KIOFINJO_00479	9.24e-93	rgfB	3.1.3.90	-	L	ko:K06896	ko00500,map00500	ko00000,ko00001,ko01000	Endonuclease/Exonuclease/phosphatase family
KIOFINJO_00480	5.86e-139	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KIOFINJO_00481	5.41e-202	ptsG	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
KIOFINJO_00482	8.33e-30	ptsG	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
KIOFINJO_00483	1.53e-68	ptsG	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
KIOFINJO_00484	2.93e-208	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
KIOFINJO_00485	3.4e-163	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOFINJO_00486	5.07e-175	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KIOFINJO_00487	1.28e-94	adcR	-	-	K	-	-	-	transcriptional
KIOFINJO_00488	1.03e-284	-	-	-	EGP	-	-	-	Major facilitator Superfamily
KIOFINJO_00489	0.0	-	-	-	KLT	-	-	-	serine threonine protein kinase
KIOFINJO_00490	1.06e-163	-	-	-	K	ko:K20374,ko:K21405	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
KIOFINJO_00491	2.41e-234	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KIOFINJO_00492	3.85e-201	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KIOFINJO_00493	3.95e-10	-	-	-	-	-	-	-	-
KIOFINJO_00494	7.63e-220	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KIOFINJO_00495	1.76e-59	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KIOFINJO_00496	8.02e-89	-	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KIOFINJO_00497	1.15e-43	oppD	-	-	P	ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KIOFINJO_00498	9.63e-38	oppD	-	-	P	ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KIOFINJO_00499	1.02e-51	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIOFINJO_00500	1.35e-64	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIOFINJO_00501	4.03e-14	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIOFINJO_00502	3.19e-36	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIOFINJO_00503	7.77e-178	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KIOFINJO_00504	7.71e-24	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KIOFINJO_00505	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
KIOFINJO_00506	2.78e-98	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
KIOFINJO_00507	4.01e-301	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KIOFINJO_00508	1.7e-298	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
KIOFINJO_00509	1.82e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KIOFINJO_00510	1.25e-248	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
KIOFINJO_00511	1.5e-174	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KIOFINJO_00512	2.48e-196	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KIOFINJO_00513	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KIOFINJO_00514	6.06e-168	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOFINJO_00516	1.42e-09	-	-	-	D	-	-	-	nuclear chromosome segregation
KIOFINJO_00517	8.47e-126	-	-	-	V	-	-	-	VanZ like family
KIOFINJO_00518	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KIOFINJO_00519	6.09e-257	XK27_00055	-	-	P	-	-	-	Major Facilitator
KIOFINJO_00520	6.64e-146	-	-	-	K	-	-	-	Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KIOFINJO_00521	2.96e-145	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KIOFINJO_00522	9.52e-303	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KIOFINJO_00523	1.1e-67	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
KIOFINJO_00524	2.53e-75	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
KIOFINJO_00525	3.58e-33	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
KIOFINJO_00526	3.09e-13	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
KIOFINJO_00527	4.95e-98	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KIOFINJO_00528	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KIOFINJO_00529	8.28e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
KIOFINJO_00530	1.03e-19	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KIOFINJO_00531	5.45e-191	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KIOFINJO_00532	5.11e-178	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KIOFINJO_00533	4.62e-40	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	nucleotide catabolic process
KIOFINJO_00534	7.42e-174	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KIOFINJO_00535	3.13e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
KIOFINJO_00536	1.61e-75	-	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
KIOFINJO_00537	5.04e-109	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
KIOFINJO_00538	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KIOFINJO_00539	6.13e-119	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KIOFINJO_00540	6.47e-286	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KIOFINJO_00541	4.13e-192	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
KIOFINJO_00542	7.24e-102	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	DNA-templated transcription, initiation
KIOFINJO_00543	1.13e-126	sipC	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
KIOFINJO_00544	1.34e-285	XK27_05225	-	-	G	-	-	-	COG0457 FOG TPR repeat
KIOFINJO_00545	2.58e-233	XK27_05220	-	-	S	-	-	-	permease
KIOFINJO_00546	3.52e-120	mutX	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NTP pyrophosphohydrolases including oxidative damage repair enzymes
KIOFINJO_00547	1.99e-209	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KIOFINJO_00548	1.04e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
KIOFINJO_00549	5.35e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KIOFINJO_00550	6.19e-263	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KIOFINJO_00551	1.23e-230	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
KIOFINJO_00552	1.97e-174	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
KIOFINJO_00553	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	cation transport ATPase
KIOFINJO_00554	1.19e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
KIOFINJO_00555	3.47e-69	XK27_00115	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	acetyltransferase
KIOFINJO_00556	2.3e-188	XK27_00835	-	-	S	-	-	-	hydrolases of the HAD superfamily
KIOFINJO_00557	1.05e-293	femX	2.3.2.10, 2.3.2.16	-	V	ko:K05363,ko:K11693	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	protein involved in methicillin resistance
KIOFINJO_00558	1.77e-197	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Metal-dependent hydrolases of the beta-lactamase superfamily I
KIOFINJO_00559	1.86e-316	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KIOFINJO_00560	1.44e-126	yycF	-	-	KT	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIOFINJO_00561	7.79e-22	yycF	-	-	KT	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIOFINJO_00562	3.14e-179	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOFINJO_00563	5.66e-193	peb1A	-	-	ET	ko:K02030,ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type amino acid transport signal transduction systems, periplasmic component domain
KIOFINJO_00564	2.9e-159	XK27_07620	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOFINJO_00565	6.09e-144	-	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
KIOFINJO_00566	1.77e-204	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
KIOFINJO_00567	4.09e-35	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
KIOFINJO_00568	5.05e-297	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KIOFINJO_00570	1.05e-250	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
KIOFINJO_00571	1.16e-17	-	-	-	G	-	-	-	Domain of unknown function (DUF4832)
KIOFINJO_00572	6.71e-266	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KIOFINJO_00573	1.95e-222	birA	6.3.4.15	-	HK	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KIOFINJO_00574	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KIOFINJO_00575	4.32e-29	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KIOFINJO_00576	2.25e-116	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
KIOFINJO_00577	1.82e-210	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KIOFINJO_00578	2.71e-27	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
KIOFINJO_00581	5.73e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KIOFINJO_00582	7.16e-278	-	-	-	P	-	-	-	chloride
KIOFINJO_00583	1.27e-55	pheA	1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5	-	E	ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
KIOFINJO_00584	0.0	eriC	-	-	P	ko:K03281	-	ko00000	Chloride transporter, ClC family
KIOFINJO_00585	4.07e-97	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
KIOFINJO_00587	4.43e-162	XK27_08875	-	-	O	-	-	-	Zinc-dependent metalloprotease
KIOFINJO_00588	3.72e-194	estA	-	CE1	S	ko:K03930	-	ko00000,ko01000	Putative esterase
KIOFINJO_00589	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KIOFINJO_00590	1.55e-173	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
KIOFINJO_00591	9.64e-191	XK27_08840	-	-	S	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KIOFINJO_00592	1.68e-229	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
KIOFINJO_00593	5.6e-17	-	-	-	S	-	-	-	Domain of unknown function (DUF4649)
KIOFINJO_00595	3.66e-51	crpB	-	-	Q	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
KIOFINJO_00596	1.34e-32	crpB	-	-	Q	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
KIOFINJO_00598	6.86e-11	crpB	-	-	Q	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
KIOFINJO_00600	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
KIOFINJO_00601	1.04e-239	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KIOFINJO_00602	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
KIOFINJO_00603	3.32e-24	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
KIOFINJO_00604	1.99e-194	XK27_00020	-	-	J	-	-	-	Belongs to the SUA5 family
KIOFINJO_00605	2.76e-146	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KIOFINJO_00606	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KIOFINJO_00607	1.11e-55	ysdA	-	-	L	-	-	-	Membrane
KIOFINJO_00608	7.51e-242	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KIOFINJO_00609	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KIOFINJO_00610	3.05e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KIOFINJO_00612	8.33e-194	usp	3.5.1.104, 3.5.1.28	CBM50	S	ko:K15125,ko:K17733,ko:K21449,ko:K21471,ko:K22278,ko:K22409	ko05133,map05133	ko00000,ko00001,ko00536,ko01000,ko01002,ko01011,ko02000	pathogenesis
KIOFINJO_00613	3.3e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
KIOFINJO_00614	9.65e-206	yitL	-	-	S	ko:K00243	-	ko00000	Protein conserved in bacteria
KIOFINJO_00615	6.76e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KIOFINJO_00616	1.38e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
KIOFINJO_00617	1.86e-157	sptS	-	-	T	-	-	-	Histidine kinase
KIOFINJO_00618	0.0	lmrA2	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
KIOFINJO_00619	3.38e-290	lmrA1	-	-	V	ko:K02021,ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
KIOFINJO_00620	1.92e-95	lmrA1	-	-	V	ko:K02021,ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
KIOFINJO_00621	4.4e-101	-	-	-	K	-	-	-	DNA-binding transcription factor activity
KIOFINJO_00622	2.73e-92	def_1	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
KIOFINJO_00623	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
KIOFINJO_00624	2.03e-275	nadR	-	-	H	-	-	-	adenylyltransferase
KIOFINJO_00625	1.68e-176	-	-	-	F	-	-	-	AdP-ribose pyrophosphatase
KIOFINJO_00626	1.12e-27	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
KIOFINJO_00627	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	abc transporter atp-binding protein
KIOFINJO_00628	7.9e-288	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KIOFINJO_00629	6.34e-179	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KIOFINJO_00630	2.03e-141	degV	-	-	T	-	-	-	EDD domain protein, DegV family
KIOFINJO_00631	5.79e-43	XK27_08360	-	-	S	-	-	-	lipid binding
KIOFINJO_00632	3.89e-84	WQ51_03320	-	-	S	-	-	-	cog cog4835
KIOFINJO_00633	2.91e-50	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KIOFINJO_00634	1.11e-128	ydaF_2	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KIOFINJO_00635	1.55e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
KIOFINJO_00636	1.99e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
KIOFINJO_00637	1.13e-37	-	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	acetyltransferase
KIOFINJO_00638	1.12e-50	-	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	acetyltransferase
KIOFINJO_00639	0.0	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KIOFINJO_00640	0.0	gtf1	-	-	M	-	-	-	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KIOFINJO_00641	4.96e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KIOFINJO_00642	1.8e-271	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
KIOFINJO_00643	2.24e-05	-	-	-	-	-	-	-	-
KIOFINJO_00645	2.19e-309	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
KIOFINJO_00646	0.0	gor	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KIOFINJO_00647	1.53e-63	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KIOFINJO_00648	1.1e-129	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KIOFINJO_00649	2.69e-35	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KIOFINJO_00650	5.31e-29	-	2.7.1.202	-	GT	ko:K02768,ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KIOFINJO_00651	8.74e-16	-	2.7.1.202	-	GT	ko:K02768,ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KIOFINJO_00652	8.93e-68	-	2.7.1.202	-	GT	ko:K02768,ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KIOFINJO_00653	5.31e-211	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KIOFINJO_00654	1.37e-165	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	transcriptional
KIOFINJO_00655	3.04e-111	-	-	-	L	ko:K07485	-	ko00000	Transposase
KIOFINJO_00656	1.63e-313	rny	-	-	D	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
KIOFINJO_00657	9.82e-164	-	-	-	L	ko:K07498	-	ko00000	Transposase
KIOFINJO_00658	6.58e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KIOFINJO_00659	9.4e-32	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KIOFINJO_00660	3.37e-119	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KIOFINJO_00661	7.25e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KIOFINJO_00662	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KIOFINJO_00663	1.19e-93	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KIOFINJO_00664	2.89e-86	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KIOFINJO_00665	2.6e-297	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KIOFINJO_00666	8.26e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
KIOFINJO_00667	3.32e-211	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
KIOFINJO_00668	1.13e-221	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	2-Nitropropane dioxygenase
KIOFINJO_00669	2.12e-40	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KIOFINJO_00670	1.88e-224	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KIOFINJO_00671	5.39e-96	XK27_02735	-	-	K	-	-	-	Transcriptional regulator, MarR family
KIOFINJO_00672	4.99e-180	phaB	5.3.3.14, 5.3.3.18	-	I	ko:K15866,ko:K18474	ko00061,ko00360,ko01120,map00061,map00360,map01120	ko00000,ko00001,ko01000,ko01004	Belongs to the enoyl-CoA hydratase isomerase family
KIOFINJO_00673	1.77e-150	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
KIOFINJO_00674	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
KIOFINJO_00675	9.23e-246	asnA	6.3.1.1	-	E	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
KIOFINJO_00676	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KIOFINJO_00677	3.96e-179	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
KIOFINJO_00678	9.83e-133	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
KIOFINJO_00679	7.97e-139	-	-	-	S	-	-	-	Domain of unknown function (DUF1803)
KIOFINJO_00680	9.95e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
KIOFINJO_00687	1.62e-137	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
KIOFINJO_00688	5.13e-95	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
KIOFINJO_00689	4.82e-78	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
KIOFINJO_00690	1.15e-89	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOFINJO_00691	7.45e-31	yecS	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	amino acid transport
KIOFINJO_00692	1.07e-09	sasH	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KIOFINJO_00693	0.0	sasH	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KIOFINJO_00694	3.06e-50	-	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	nucleotide catabolic process
KIOFINJO_00695	4.28e-133	yfiF3	-	-	K	-	-	-	sequence-specific DNA binding
KIOFINJO_00696	1.76e-28	bglC	-	-	K	-	-	-	Transcriptional regulator
KIOFINJO_00697	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KIOFINJO_00698	2.03e-306	agcS	-	-	E	ko:K03310	-	ko00000	(Alanine) symporter
KIOFINJO_00699	1.57e-265	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
KIOFINJO_00700	1.37e-249	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
KIOFINJO_00701	2.08e-307	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	o-acetylhomoserine
KIOFINJO_00702	6.24e-78	-	-	-	Q	-	-	-	phosphatase activity
KIOFINJO_00703	5.48e-79	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
KIOFINJO_00704	1.48e-114	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KIOFINJO_00705	3.31e-143	hsdS2	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
KIOFINJO_00706	2.2e-278	XK27_04775	-	-	S	ko:K09155	-	ko00000	hemerythrin HHE cation binding domain
KIOFINJO_00707	4.02e-193	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KIOFINJO_00708	4.8e-223	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
KIOFINJO_00709	7.52e-95	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KIOFINJO_00710	1.7e-59	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
KIOFINJO_00711	5.9e-184	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
KIOFINJO_00712	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
KIOFINJO_00713	3.94e-202	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	phosphate
KIOFINJO_00714	4.63e-201	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
KIOFINJO_00715	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	phosphate transport system permease
KIOFINJO_00716	5.27e-193	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KIOFINJO_00717	1.24e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KIOFINJO_00718	1.1e-147	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
KIOFINJO_00719	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
KIOFINJO_00720	1.32e-249	xerS	-	-	D	ko:K04763	-	ko00000,ko03036	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
KIOFINJO_00722	2.63e-240	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
KIOFINJO_00725	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KIOFINJO_00726	3.99e-92	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
KIOFINJO_00727	1.36e-233	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
KIOFINJO_00728	2.89e-228	malR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
KIOFINJO_00729	6.6e-25	malX	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KIOFINJO_00730	1.94e-18	malX	-	-	G	ko:K02027,ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	maltose binding
KIOFINJO_00731	3.01e-36	malX	-	-	G	ko:K02027,ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	maltose binding
KIOFINJO_00732	1.82e-59	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOFINJO_00733	1.17e-55	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOFINJO_00734	4.79e-34	tatA	-	-	U	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein secretion
KIOFINJO_00735	3.17e-157	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KIOFINJO_00736	0.0	ywbL	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
KIOFINJO_00737	2.59e-297	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	peroxidase
KIOFINJO_00738	2.5e-199	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
KIOFINJO_00739	1.38e-231	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type enterochelin transport system, periplasmic component
KIOFINJO_00740	1.75e-174	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOFINJO_00741	6.34e-214	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KIOFINJO_00742	7.09e-211	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KIOFINJO_00743	1.97e-43	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
KIOFINJO_00744	4.31e-270	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
KIOFINJO_00745	8.37e-76	hsdS	2.1.1.72, 3.1.21.3	-	V	ko:K01154,ko:K07317	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
KIOFINJO_00746	2.42e-81	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
KIOFINJO_00747	2.44e-43	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
KIOFINJO_00748	6.91e-203	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
KIOFINJO_00749	5.25e-08	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
KIOFINJO_00750	4.83e-97	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
KIOFINJO_00751	2e-73	XK27_10720	-	-	D	-	-	-	peptidase activity
KIOFINJO_00752	0.0	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
KIOFINJO_00755	3.33e-139	-	-	-	L	ko:K07485	-	ko00000	Transposase
KIOFINJO_00756	2.29e-62	-	-	-	-	-	-	-	-
KIOFINJO_00757	6.17e-24	-	-	-	-	ko:K07485	-	ko00000	-
KIOFINJO_00758	1.3e-218	yeiH	-	-	S	-	-	-	Membrane
KIOFINJO_00759	4.02e-147	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	muramidase
KIOFINJO_00760	1.85e-125	-	-	-	L	ko:K07497	-	ko00000	transposition
KIOFINJO_00761	2.18e-214	cpsY	-	-	K	-	-	-	Transcriptional regulator
KIOFINJO_00762	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KIOFINJO_00763	7.71e-77	phnA	-	-	P	ko:K06193	ko01120,map01120	ko00000	Alkylphosphonate utilization operon protein PhnA
KIOFINJO_00764	1.26e-62	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter (Permease
KIOFINJO_00765	5.28e-146	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOFINJO_00766	9.52e-204	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
KIOFINJO_00767	1.97e-191	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KIOFINJO_00768	2.18e-10	-	-	-	-	-	-	-	-
KIOFINJO_00769	5.44e-34	-	-	-	-	-	-	-	-
KIOFINJO_00770	1.96e-82	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
KIOFINJO_00771	2.22e-22	adhP	1.1.1.1	-	P	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
KIOFINJO_00772	4.41e-106	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
KIOFINJO_00773	7.95e-30	-	-	-	-	-	-	-	-
KIOFINJO_00774	0.0	sthIR	3.1.21.5	-	S	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction
KIOFINJO_00775	0.0	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	Adenine specific DNA methylase Mod
KIOFINJO_00776	1.51e-115	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	Adenine specific DNA methylase Mod
KIOFINJO_00777	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
KIOFINJO_00778	1.05e-161	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
KIOFINJO_00779	9e-72	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KIOFINJO_00780	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KIOFINJO_00781	5.63e-113	niaX	-	-	-	ko:K16788	-	ko00000,ko02000	-
KIOFINJO_00782	7.82e-118	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
KIOFINJO_00783	1.21e-93	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
KIOFINJO_00784	6.36e-54	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
KIOFINJO_00785	1.46e-203	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KIOFINJO_00786	1.72e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KIOFINJO_00787	5.35e-217	-	-	-	GK	-	-	-	ROK family
KIOFINJO_00788	2e-203	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
KIOFINJO_00789	1.25e-89	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KIOFINJO_00790	5.38e-68	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KIOFINJO_00791	3.76e-306	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KIOFINJO_00792	1.03e-198	-	-	-	S	-	-	-	TraX protein
KIOFINJO_00793	2.93e-157	spaR	-	-	KT	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIOFINJO_00794	0.0	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
KIOFINJO_00795	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KIOFINJO_00796	1.03e-197	XK27_05470	-	-	E	-	-	-	Methionine synthase
KIOFINJO_00797	1.84e-32	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KIOFINJO_00798	1.54e-46	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KIOFINJO_00799	1.81e-61	pspE	-	-	P	ko:K03972	-	ko00000	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KIOFINJO_00800	5.99e-118	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
KIOFINJO_00801	3.14e-71	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	Acetoin reductase
KIOFINJO_00802	1.01e-24	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	Acetoin reductase
KIOFINJO_00803	2.92e-303	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KIOFINJO_00804	3.51e-86	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KIOFINJO_00808	3.63e-71	-	-	-	K	ko:K15773	-	ko00000,ko02048,ko03000	peptidyl-tyrosine sulfation
KIOFINJO_00809	4.48e-170	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KIOFINJO_00810	3.37e-176	nikQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport protein
KIOFINJO_00811	7.11e-227	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
KIOFINJO_00812	2.96e-205	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KIOFINJO_00813	4.71e-142	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KIOFINJO_00814	1.83e-169	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KIOFINJO_00815	2.25e-100	ureE	-	-	O	ko:K03187	-	ko00000	enzyme active site formation
KIOFINJO_00816	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KIOFINJO_00817	3.78e-72	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
KIOFINJO_00818	1.02e-61	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
KIOFINJO_00819	7.25e-123	ureI	-	-	S	ko:K03191	ko05120,map05120	ko00000,ko00001,ko02000	AmiS/UreI family transporter
KIOFINJO_00820	1.17e-65	-	-	-	S	-	-	-	Domain of unknown function (DUF4173)
KIOFINJO_00821	9.51e-43	-	-	-	S	-	-	-	Domain of unknown function (DUF4173)
KIOFINJO_00822	6.22e-58	yhaI	-	-	L	-	-	-	Membrane
KIOFINJO_00823	9.82e-92	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KIOFINJO_00824	4.06e-81	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	protein secretion by the type I secretion system
KIOFINJO_00825	5.61e-46	-	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	protein secretion by the type I secretion system
KIOFINJO_00826	7.97e-147	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KIOFINJO_00827	3.36e-46	-	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	protein secretion by the type I secretion system
KIOFINJO_00828	1.46e-206	-	-	-	K	ko:K20342,ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
KIOFINJO_00829	2.22e-146	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Membrane-associated phospholipid phosphatase
KIOFINJO_00830	4.83e-118	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KIOFINJO_00831	6.62e-103	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KIOFINJO_00832	2.41e-315	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	Potassium transporter peripheral membrane component
KIOFINJO_00833	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
KIOFINJO_00834	6.55e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
KIOFINJO_00835	3.14e-179	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
KIOFINJO_00836	7.56e-129	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KIOFINJO_00837	1.66e-156	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KIOFINJO_00838	3.55e-176	xerD	-	-	L	-	-	-	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
KIOFINJO_00839	1.49e-112	ykuL	-	-	S	-	-	-	CBS domain
KIOFINJO_00840	7.82e-128	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
KIOFINJO_00841	2.33e-236	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KIOFINJO_00842	9.38e-189	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
KIOFINJO_00843	5.74e-48	-	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
KIOFINJO_00844	3.67e-120	-	-	-	K	-	-	-	transcriptional regulator
KIOFINJO_00845	1.42e-310	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KIOFINJO_00848	2.43e-145	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
KIOFINJO_00849	8.25e-121	XK27_09705	-	-	S	ko:K06950	-	ko00000	HD superfamily hydrolase
KIOFINJO_00850	6.83e-169	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KIOFINJO_00851	9.51e-61	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
KIOFINJO_00852	5.31e-212	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KIOFINJO_00853	1.13e-108	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
KIOFINJO_00854	1.17e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KIOFINJO_00855	0.0	mltG	-	-	ADL	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KIOFINJO_00856	5.33e-76	XK27_09675	-	-	K	ko:K07105	-	ko00000	-acetyltransferase
KIOFINJO_00857	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
KIOFINJO_00858	3.69e-27	XK27_11680	-	-	-	-	-	-	-
KIOFINJO_00859	0.0	snf	-	-	L	-	-	-	Superfamily II DNA RNA helicases, SNF2 family'
KIOFINJO_00860	4.11e-123	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KIOFINJO_00861	1.02e-158	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
KIOFINJO_00862	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KIOFINJO_00863	3.86e-143	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
KIOFINJO_00864	1.3e-214	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
KIOFINJO_00865	1.52e-57	acuB	-	-	S	ko:K04767	-	ko00000	IMP dehydrogenase activity
KIOFINJO_00866	2.41e-92	acuB	-	-	S	ko:K04767	-	ko00000	IMP dehydrogenase activity
KIOFINJO_00867	1.32e-157	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
KIOFINJO_00868	6.57e-176	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
KIOFINJO_00869	7.76e-183	livM	-	-	E	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KIOFINJO_00870	8.19e-190	livH	-	-	E	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KIOFINJO_00871	3.94e-271	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
KIOFINJO_00872	4.33e-62	ylbG	-	-	S	-	-	-	UPF0298 protein
KIOFINJO_00873	2.34e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
KIOFINJO_00874	1.53e-134	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KIOFINJO_00875	1.06e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KIOFINJO_00876	3.28e-06	sacB	2.4.1.10, 2.4.1.9	GH68	G	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Belongs to the glycosyl hydrolase 68 family
KIOFINJO_00878	5.65e-286	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KIOFINJO_00879	1.76e-258	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
KIOFINJO_00880	3.07e-114	pacL	-	-	P	-	-	-	cation transport ATPase
KIOFINJO_00881	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
KIOFINJO_00882	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KIOFINJO_00883	9.48e-300	femA	2.3.2.17	-	V	ko:K11694	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	protein involved in methicillin resistance
KIOFINJO_00885	1.63e-50	-	3.2.2.10	-	L	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
KIOFINJO_00886	1.44e-29	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
KIOFINJO_00887	9.81e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KIOFINJO_00888	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KIOFINJO_00889	2.19e-56	ylxQ	-	-	J	-	-	-	ribosomal protein
KIOFINJO_00890	6.68e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Nucleic-acid-binding protein implicated in transcription termination
KIOFINJO_00891	2.65e-270	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
KIOFINJO_00892	3.06e-105	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
KIOFINJO_00893	1.29e-280	brpA	-	-	K	-	-	-	Transcriptional
KIOFINJO_00894	6.67e-120	-	-	-	M	-	-	-	Acetyltransferase GNAT Family
KIOFINJO_00895	1.54e-101	ydiB	-	-	M	ko:K06925	-	ko00000,ko03016	ATPase or kinase
KIOFINJO_00896	3.61e-206	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
KIOFINJO_00897	3.9e-91	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
KIOFINJO_00898	3.94e-190	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
KIOFINJO_00899	1.84e-181	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Metal-dependent hydrolase
KIOFINJO_00900	5.66e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
KIOFINJO_00901	4.38e-164	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	pts system
KIOFINJO_00902	2.99e-217	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
KIOFINJO_00903	1.85e-82	manO	-	-	S	-	-	-	protein conserved in bacteria
KIOFINJO_00904	4.86e-308	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KIOFINJO_00905	5.89e-30	-	-	-	S	-	-	-	Protein of unknown function DUF262
KIOFINJO_00906	8.33e-234	-	-	-	S	-	-	-	CRISPR-associated protein Csn2 subfamily St
KIOFINJO_00907	8.44e-71	-	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KIOFINJO_00908	6.55e-221	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KIOFINJO_00909	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KIOFINJO_00910	3.62e-123	-	-	-	-	-	-	-	-
KIOFINJO_00912	4.96e-59	dam	2.1.1.72	-	L	ko:K07318	-	ko00000,ko01000,ko02048	D12 class N6 adenine-specific DNA methyltransferase
KIOFINJO_00913	2.13e-44	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
KIOFINJO_00914	4.4e-110	-	-	-	-	-	-	-	-
KIOFINJO_00915	0.0	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KIOFINJO_00916	7.4e-126	mip	-	-	S	-	-	-	hydroperoxide reductase activity
KIOFINJO_00917	4.67e-258	-	-	-	I	-	-	-	acyl-CoA dehydrogenase
KIOFINJO_00918	1.23e-205	ydiA	-	-	P	ko:K11041	ko05150,map05150	ko00000,ko00001,ko02042	C4-dicarboxylate transporter malic acid transport
KIOFINJO_00919	4.81e-136	msrR	-	-	K	-	-	-	Transcriptional regulator
KIOFINJO_00920	2.79e-85	msrR	-	-	K	-	-	-	Transcriptional regulator
KIOFINJO_00921	3.43e-197	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
KIOFINJO_00922	1.6e-113	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KIOFINJO_00923	1.02e-298	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KIOFINJO_00924	2.67e-222	hicD2	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
KIOFINJO_00925	1.48e-71	XK26_04240	-	-	S	-	-	-	Belongs to the UPF0342 family
KIOFINJO_00926	1.11e-263	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
KIOFINJO_00927	1.29e-279	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KIOFINJO_00928	2.5e-258	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KIOFINJO_00929	1.96e-207	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KIOFINJO_00930	3.99e-158	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KIOFINJO_00931	2.51e-281	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
KIOFINJO_00932	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
KIOFINJO_00933	5.04e-314	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KIOFINJO_00934	1.03e-101	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
KIOFINJO_00935	1.71e-264	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
KIOFINJO_00936	9.83e-187	XK27_07735	-	-	S	-	-	-	YjbR
KIOFINJO_00937	1.2e-33	XK27_07735	-	-	S	-	-	-	YjbR
KIOFINJO_00938	1.34e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	Catabolite control protein A
KIOFINJO_00939	9.95e-268	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Belongs to the peptidase M24B family
KIOFINJO_00940	1.08e-84	yugI	-	-	J	ko:K07570	-	ko00000	RNA binding protein, contains ribosomal protein S1 domain
KIOFINJO_00941	0.0	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KIOFINJO_00942	5.69e-105	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KIOFINJO_00943	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KIOFINJO_00944	1.06e-44	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
KIOFINJO_00945	7.22e-282	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	Major Facilitator
KIOFINJO_00946	4.45e-136	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KIOFINJO_00947	2.33e-199	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KIOFINJO_00948	2.35e-212	era	-	-	M	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KIOFINJO_00949	1.16e-83	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
KIOFINJO_00950	2.18e-112	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KIOFINJO_00951	9.96e-69	licT	-	-	K	ko:K02538,ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
KIOFINJO_00952	3.61e-84	licT	-	-	K	ko:K02538,ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
KIOFINJO_00953	1.85e-136	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KIOFINJO_00954	4.37e-152	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
KIOFINJO_00955	1.9e-253	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
KIOFINJO_00956	5.03e-192	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KIOFINJO_00957	1.71e-202	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KIOFINJO_00958	5.04e-29	-	-	-	I	-	-	-	Alpha/beta hydrolase family
KIOFINJO_00959	2.87e-47	yugF	-	-	I	-	-	-	carboxylic ester hydrolase activity
KIOFINJO_00960	6.95e-12	-	-	-	-	-	-	-	-
KIOFINJO_00961	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
KIOFINJO_00962	8.63e-102	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain protein
KIOFINJO_00963	4.45e-169	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOFINJO_00964	3.24e-151	-	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KIOFINJO_00965	1.15e-47	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
KIOFINJO_00966	5.71e-234	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KIOFINJO_00967	2.87e-315	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
KIOFINJO_00968	6.22e-167	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
KIOFINJO_00969	7.82e-111	XK27_09440	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
KIOFINJO_00970	5.47e-66	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
KIOFINJO_00971	2.66e-68	ydgJ	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	inositol 2-dehydrogenase activity
KIOFINJO_00972	1.61e-36	-	2.7.7.15	-	S	ko:K00968	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	inositol 2-dehydrogenase activity
KIOFINJO_00973	8.6e-11	-	-	-	S	-	-	-	oxidoreductase
KIOFINJO_00974	9.58e-104	murN	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	FemAB family
KIOFINJO_00975	4.23e-165	murN	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	FemAB family
KIOFINJO_00976	1.37e-87	-	-	-	M	-	-	-	Pfam SNARE associated Golgi protein
KIOFINJO_00977	5.3e-41	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
KIOFINJO_00978	9.86e-38	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
KIOFINJO_00981	1.44e-268	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein S1
KIOFINJO_00984	3.44e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
KIOFINJO_00985	4.29e-256	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KIOFINJO_00986	5e-300	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KIOFINJO_00987	9.73e-257	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KIOFINJO_00988	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KIOFINJO_00989	1.49e-138	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KIOFINJO_00990	1.1e-20	-	-	-	L	-	-	-	Helix-hairpin-helix DNA-binding motif class 1
KIOFINJO_00991	5.22e-41	-	-	-	S	-	-	-	Domain of unknown function (DUF1912)
KIOFINJO_00992	3.53e-227	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	Homocysteine
KIOFINJO_00993	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
KIOFINJO_00994	6.75e-144	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
KIOFINJO_00995	3.61e-224	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KIOFINJO_00996	5.17e-50	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KIOFINJO_00997	2.97e-30	-	-	-	-	-	-	-	-
KIOFINJO_00998	7.02e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KIOFINJO_00999	3.63e-214	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KIOFINJO_01000	3.13e-279	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	synthase
KIOFINJO_01001	6.15e-298	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
KIOFINJO_01002	1.05e-153	hly-III	-	-	K	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
KIOFINJO_01003	6.8e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
KIOFINJO_01004	2.02e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
KIOFINJO_01005	2.88e-220	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KIOFINJO_01006	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KIOFINJO_01007	5.47e-29	-	-	-	-	-	-	-	-
KIOFINJO_01008	0.0	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
KIOFINJO_01009	4.93e-243	dgs	2.4.1.208	GT4	M	ko:K13677	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
KIOFINJO_01010	1.15e-59	-	-	-	M	ko:K02460	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	domain protein
KIOFINJO_01011	9.15e-10	-	-	-	M	ko:K02460	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	domain protein
KIOFINJO_01013	7.33e-152	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KIOFINJO_01014	1.47e-41	-	-	-	-	-	-	-	-
KIOFINJO_01015	8.64e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	AdP-ribose pyrophosphatase
KIOFINJO_01016	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KIOFINJO_01017	3.21e-244	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KIOFINJO_01018	8.32e-229	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
KIOFINJO_01019	3.24e-222	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
KIOFINJO_01020	2.19e-193	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
KIOFINJO_01021	3.96e-137	-	-	-	J	ko:K09962	-	ko00000	protein conserved in bacteria
KIOFINJO_01022	0.0	merA	-	-	C	-	-	-	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KIOFINJO_01024	3.82e-57	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
KIOFINJO_01025	1.29e-24	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	alanine dehydrogenase activity
KIOFINJO_01026	3.04e-279	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KIOFINJO_01027	3.68e-170	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
KIOFINJO_01028	8.88e-147	-	-	-	S	-	-	-	VIT family
KIOFINJO_01029	3.69e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
KIOFINJO_01031	3.94e-40	XK27_00085	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
KIOFINJO_01032	3.93e-250	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
KIOFINJO_01033	1.79e-157	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
KIOFINJO_01034	1.17e-214	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
KIOFINJO_01035	1.96e-280	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KIOFINJO_01036	3.51e-170	rr02	-	-	KT	-	-	-	response regulator
KIOFINJO_01037	2.59e-294	hk02	-	-	T	-	-	-	signal transduction protein with a C-terminal ATPase domain
KIOFINJO_01038	1.03e-163	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KIOFINJO_01039	1.09e-248	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KIOFINJO_01040	0.0	lmrA	-	-	V	ko:K06147,ko:K18888	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
KIOFINJO_01041	0.0	msbA_1	-	-	V	ko:K18887	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
KIOFINJO_01043	2.46e-69	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KIOFINJO_01044	3.14e-101	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KIOFINJO_01045	4.71e-37	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	efflux transmembrane transporter activity
KIOFINJO_01046	6.91e-34	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	efflux transmembrane transporter activity
KIOFINJO_01047	8.95e-44	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	permease protein
KIOFINJO_01048	5.34e-54	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	permease protein
KIOFINJO_01049	4.46e-48	yknX	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KIOFINJO_01050	1.86e-34	yknX	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KIOFINJO_01051	9.74e-161	-	-	-	J	-	-	-	Putative SAM-dependent methyltransferase
KIOFINJO_01052	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthetase ammonia chain
KIOFINJO_01053	1.12e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthetase glutamine chain
KIOFINJO_01054	8.28e-222	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
KIOFINJO_01055	2.87e-288	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	uracil Permease
KIOFINJO_01056	6.68e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KIOFINJO_01057	3.6e-210	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
KIOFINJO_01058	1.4e-100	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KIOFINJO_01059	3.2e-214	lysR	-	-	K	-	-	-	transcriptional regulator (lysR family)
KIOFINJO_01064	2.29e-75	ppiA	5.2.1.8	-	O	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KIOFINJO_01065	2.72e-102	-	2.7.1.211	-	G	ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	PTS glucose transporter subunit IIA
KIOFINJO_01066	3.13e-122	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
KIOFINJO_01067	6.05e-93	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
KIOFINJO_01068	3.11e-35	-	2.7.1.208, 2.7.1.211	-	G	ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KIOFINJO_01070	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	permease
KIOFINJO_01071	1.42e-52	ynzC	-	-	S	-	-	-	UPF0291 protein
KIOFINJO_01072	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
KIOFINJO_01073	1.36e-33	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
KIOFINJO_01074	2.48e-226	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
KIOFINJO_01075	3.77e-81	-	-	-	-	-	-	-	-
KIOFINJO_01076	3.92e-34	-	-	-	-	-	-	-	-
KIOFINJO_01077	4.34e-73	-	-	-	-	-	-	-	-
KIOFINJO_01078	7.12e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KIOFINJO_01079	1.78e-32	yjbB	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
KIOFINJO_01080	2.33e-36	phoU_1	-	-	P	ko:K03324	-	ko00000,ko02000	sodium-dependent phosphate transmembrane transporter activity
KIOFINJO_01081	2.01e-42	phoU_1	-	-	P	ko:K03324	-	ko00000,ko02000	sodium-dependent phosphate transmembrane transporter activity
KIOFINJO_01082	7.55e-192	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KIOFINJO_01083	2.28e-140	mur1	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	mannosyl-glycoprotein
KIOFINJO_01084	3.27e-71	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
KIOFINJO_01085	1.26e-297	amt	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium Transporter
KIOFINJO_01086	7.25e-206	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KIOFINJO_01087	2.84e-73	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
KIOFINJO_01088	8.56e-179	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
KIOFINJO_01089	1.58e-206	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	dna polymerase iii
KIOFINJO_01090	5.91e-143	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KIOFINJO_01091	6.58e-175	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KIOFINJO_01092	7.86e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KIOFINJO_01093	1.43e-292	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
KIOFINJO_01094	6.23e-97	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
KIOFINJO_01095	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KIOFINJO_01096	9.48e-204	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KIOFINJO_01097	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KIOFINJO_01098	1.05e-114	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KIOFINJO_01099	1.78e-102	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase F(0) sector subunit b
KIOFINJO_01100	2.46e-157	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
KIOFINJO_01101	5.88e-23	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KIOFINJO_01102	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KIOFINJO_01103	7.86e-23	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KIOFINJO_01104	7.34e-63	-	2.3.1.128, 5.2.1.8	-	J	ko:K03768,ko:K03790	-	ko00000,ko01000,ko03009,ko03110	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KIOFINJO_01105	1.55e-131	-	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KIOFINJO_01106	3.61e-17	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
KIOFINJO_01108	5.44e-30	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	Transporter
KIOFINJO_01109	6.45e-96	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	Transporter
KIOFINJO_01110	1.29e-198	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KIOFINJO_01111	1.47e-303	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
KIOFINJO_01112	9.02e-132	icaB	-	-	G	-	-	-	deacetylase
KIOFINJO_01113	6.48e-267	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
KIOFINJO_01114	7.33e-164	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
KIOFINJO_01115	2.82e-94	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KIOFINJO_01116	1.76e-173	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KIOFINJO_01117	8.21e-245	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KIOFINJO_01118	8.57e-292	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	mutations do not affect methionine salvage in vivo however
KIOFINJO_01119	2.32e-189	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KIOFINJO_01120	2.35e-184	-	3.4.17.14, 3.5.1.28	-	NU	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036	amidase activity
KIOFINJO_01121	6.15e-57	-	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	pathogenesis
KIOFINJO_01122	4.2e-131	-	-	-	M	-	-	-	GBS Bsp-like repeat
KIOFINJO_01123	1.22e-29	-	-	-	M	-	-	-	GBS Bsp-like repeat
KIOFINJO_01124	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KIOFINJO_01125	3.25e-237	prsA	3.1.3.16, 5.2.1.8	-	O	ko:K01802,ko:K03769,ko:K07533,ko:K20074	-	ko00000,ko01000,ko01009,ko03110	peptidyl-prolyl cis-trans isomerase activity
KIOFINJO_01126	2.39e-164	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-Methyltransferase
KIOFINJO_01127	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
KIOFINJO_01128	3.31e-238	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
KIOFINJO_01129	9.23e-214	-	-	-	K	-	-	-	transcriptional regulator (lysR family)
KIOFINJO_01130	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KIOFINJO_01134	9.19e-244	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
KIOFINJO_01135	1.12e-90	sip	-	-	M	-	-	-	LysM domain protein
KIOFINJO_01136	5.13e-170	pcsB	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
KIOFINJO_01137	1.52e-116	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KIOFINJO_01138	2.45e-182	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
KIOFINJO_01143	3.27e-34	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
KIOFINJO_01144	1.12e-13	rfaB	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
KIOFINJO_01145	8.26e-87	-	-	-	L	ko:K07498	-	ko00000	DDE domain
KIOFINJO_01146	1.32e-11	-	-	-	L	ko:K07498	-	ko00000	DDE domain
KIOFINJO_01147	6.15e-118	-	-	-	V	-	-	-	VanZ like family
KIOFINJO_01148	4.28e-128	cps2J	-	-	S	-	-	-	Polysaccharide biosynthesis protein
KIOFINJO_01149	8.18e-64	-	-	-	GM	-	-	-	Polysaccharide pyruvyl transferase
KIOFINJO_01150	6.09e-19	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
KIOFINJO_01151	5.95e-08	-	-	-	S	-	-	-	EpsG family
KIOFINJO_01152	2.44e-72	-	-	-	S	-	-	-	Glycosyltransferase like family 2
KIOFINJO_01153	1.18e-48	-	2.3.1.79	-	M	ko:K00661	-	ko00000,ko01000	Hexapeptide repeat of succinyl-transferase
KIOFINJO_01154	2.32e-67	-	-	-	G	-	-	-	Glycosyl transferase 4-like domain
KIOFINJO_01155	5.44e-104	-	-	-	M	-	-	-	Glycosyl transferase 4-like
KIOFINJO_01157	3.82e-74	-	-	-	M	-	-	-	Bacterial sugar transferase
KIOFINJO_01158	1.89e-149	cpsD	-	-	D	-	-	-	COG0489 ATPases involved in chromosome partitioning
KIOFINJO_01159	4.95e-150	capA	-	-	M	-	-	-	biosynthesis protein
KIOFINJO_01160	1.1e-173	cpsB	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	Capsular polysaccharide biosynthesis protein
KIOFINJO_01161	3.18e-315	cps4A	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
KIOFINJO_01162	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	purine nucleoside phosphorylase
KIOFINJO_01163	9.24e-153	gat	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	glutamine amidotransferase
KIOFINJO_01164	2.97e-72	clcA_2	-	-	P	ko:K03281	-	ko00000	chloride channel
KIOFINJO_01165	5.05e-192	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KIOFINJO_01166	5.55e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1697)
KIOFINJO_01167	4.48e-299	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KIOFINJO_01168	2.91e-156	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KIOFINJO_01169	4.42e-45	-	-	-	V	-	-	-	Glucan-binding protein C
KIOFINJO_01170	2.28e-144	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
KIOFINJO_01171	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Dipeptidase
KIOFINJO_01172	2.78e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
KIOFINJO_01173	9.78e-112	XK27_03610	-	-	K	-	-	-	Gnat family
KIOFINJO_01174	1.39e-33	-	-	-	L	ko:K07491	-	ko00000	Transposase
KIOFINJO_01175	1.61e-55	-	-	-	L	ko:K07491	-	ko00000	Transposase
KIOFINJO_01176	1.82e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KIOFINJO_01177	5.79e-39	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
KIOFINJO_01178	1.56e-115	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KIOFINJO_01179	1.44e-156	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
KIOFINJO_01180	1.64e-42	XK27_09115	-	-	M	-	-	-	LysM domain
KIOFINJO_01181	1.12e-119	ebsA	-	-	S	-	-	-	Family of unknown function (DUF5322)
KIOFINJO_01182	1.76e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
KIOFINJO_01184	3.12e-100	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	carboxypeptidase activity
KIOFINJO_01185	1.77e-119	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
KIOFINJO_01187	2.48e-176	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
KIOFINJO_01188	1.73e-232	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KIOFINJO_01189	3.55e-109	-	-	-	S	-	-	-	Putative small multi-drug export protein
KIOFINJO_01190	1.15e-98	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
KIOFINJO_01191	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
KIOFINJO_01192	1.96e-130	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
KIOFINJO_01193	3.56e-65	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
KIOFINJO_01194	6.81e-295	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
KIOFINJO_01195	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KIOFINJO_01196	3.84e-185	-	-	-	S	-	-	-	SseB protein N-terminal domain
KIOFINJO_01197	7.75e-145	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine acetyltransferase
KIOFINJO_01198	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
KIOFINJO_01199	2.1e-90	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KIOFINJO_01202	1.23e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KIOFINJO_01203	6.97e-121	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
KIOFINJO_01204	2.23e-199	yitS	-	-	S	-	-	-	DegV family
KIOFINJO_01205	1.22e-42	-	-	-	K	-	-	-	helix-turn-helix
KIOFINJO_01206	4e-234	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KIOFINJO_01207	7.02e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KIOFINJO_01208	1.49e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
KIOFINJO_01209	3.37e-43	-	-	-	K	-	-	-	Peptidase S24-like
KIOFINJO_01211	6.28e-125	-	-	-	S	ko:K20483	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lantibiotic dehydratase, C terminus
KIOFINJO_01212	0.0	-	-	-	S	ko:K20483	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lantibiotic dehydratase, C terminus
KIOFINJO_01213	1.97e-295	spaC2	-	-	V	ko:K20484	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lanthionine synthetase C family protein
KIOFINJO_01214	2.6e-236	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KIOFINJO_01215	5.31e-120	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Divergent AAA domain protein
KIOFINJO_01216	3.75e-63	int	-	-	L	-	-	-	Belongs to the 'phage' integrase family
KIOFINJO_01217	9.43e-34	int	-	-	L	-	-	-	Belongs to the 'phage' integrase family
KIOFINJO_01218	8.09e-19	-	-	-	S	-	-	-	Helix-turn-helix domain
KIOFINJO_01220	1.43e-169	-	-	-	-	-	-	-	-
KIOFINJO_01221	2.1e-52	-	-	-	-	-	-	-	-
KIOFINJO_01222	3.51e-27	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
KIOFINJO_01223	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KIOFINJO_01224	3.03e-257	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KIOFINJO_01225	4.86e-74	yitW	-	-	K	-	-	-	metal-sulfur cluster biosynthetic enzyme
KIOFINJO_01226	1.37e-220	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	COG0463, glycosyltransferases involved in cell wall biogenesis
KIOFINJO_01227	1.9e-207	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KIOFINJO_01228	1.68e-277	-	-	-	S	-	-	-	membrane protein involved in the export of O-antigen and teichoic acid
KIOFINJO_01229	3.53e-178	-	-	-	M	-	-	-	Glycosyltransferase group 2 family protein
KIOFINJO_01230	4.19e-51	arnC	-	-	M	ko:K00786	-	ko00000,ko01000	group 2 family protein
KIOFINJO_01231	1.69e-161	-	-	-	S	-	-	-	Glycosyl transferase family 2
KIOFINJO_01232	2.21e-63	-	-	-	S	ko:K09153	-	ko00000	Uncharacterized conserved protein (DUF2304)
KIOFINJO_01233	1.07e-134	-	-	-	S	-	-	-	Glycosyltransferase group 2 family protein
KIOFINJO_01234	7.51e-285	rgpA	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
KIOFINJO_01235	1.14e-226	rgpB	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
KIOFINJO_01236	1.38e-184	rgpC	-	-	GM	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
KIOFINJO_01237	2.99e-291	rgpD	3.6.3.40	-	P	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KIOFINJO_01238	0.0	-	-	GT4	M	ko:K00754	-	ko00000,ko01000	transferase activity, transferring glycosyl groups
KIOFINJO_01239	0.0	rgpF	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
KIOFINJO_01240	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
KIOFINJO_01241	7.98e-155	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
KIOFINJO_01242	1.83e-166	-	-	-	T	ko:K07010	-	ko00000,ko01002	peptidase C26
KIOFINJO_01243	9.11e-151	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KIOFINJO_01244	1.77e-78	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
KIOFINJO_01245	1.12e-264	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
KIOFINJO_01246	2.07e-226	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KIOFINJO_01247	5.5e-134	yjbK	-	-	S	-	-	-	Adenylate cyclase
KIOFINJO_01248	5.61e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Gtp pyrophosphokinase
KIOFINJO_01249	1.19e-197	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KIOFINJO_01250	7.67e-222	yjbO	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
KIOFINJO_01251	1.15e-233	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
KIOFINJO_01252	5.86e-52	-	-	-	L	ko:K07483	-	ko00000	transposase activity
KIOFINJO_01253	2.9e-29	-	-	-	L	-	-	-	Transposase
KIOFINJO_01254	2.04e-38	-	-	-	L	ko:K07497	-	ko00000	transposition
KIOFINJO_01255	9.59e-141	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
KIOFINJO_01256	3.41e-277	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
KIOFINJO_01257	8.42e-51	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	Hydrolase, tatd
KIOFINJO_01258	6.36e-187	dtpT	-	-	U	ko:K03305	-	ko00000	POT family
KIOFINJO_01259	1.06e-95	dtpT	-	-	E	ko:K03305	-	ko00000	transporter
KIOFINJO_01260	9.11e-77	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
KIOFINJO_01261	2.58e-11	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	amidase activity
KIOFINJO_01262	6.16e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KIOFINJO_01263	6.87e-162	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KIOFINJO_01264	3.25e-92	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
KIOFINJO_01265	4.72e-18	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
KIOFINJO_01266	3.18e-262	csm5	-	-	L	ko:K19140	-	ko00000,ko02048	CRISPR-associated RAMP protein, Csm5 family
KIOFINJO_01267	2.1e-215	csm4	-	-	L	ko:K19139	-	ko00000,ko02048	CRISPR-associated RAMP protein, Csm4 family
KIOFINJO_01268	8.03e-151	csm3	-	-	L	ko:K09002	-	ko00000,ko02048	RAMP superfamily
KIOFINJO_01269	7.5e-83	-	-	-	L	ko:K19138	-	ko00000,ko02048	Pfam:DUF310
KIOFINJO_01270	0.0	csm1	-	-	S	ko:K07016	-	ko00000,ko02048	CRISPR-associated protein Csm1 family
KIOFINJO_01271	1.32e-98	csm1	-	-	S	ko:K07016	-	ko00000,ko02048	CRISPR-associated protein Csm1 family
KIOFINJO_01272	7.74e-174	-	-	-	S	-	-	-	Pfam:DUF2276
KIOFINJO_01273	2.91e-72	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KIOFINJO_01274	3.79e-92	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	maintenance of DNA repeat elements
KIOFINJO_01275	7.21e-143	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	maintenance of DNA repeat elements
KIOFINJO_01276	1.28e-224	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KIOFINJO_01277	5.05e-191	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KIOFINJO_01278	2.12e-125	thiJ	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1 family
KIOFINJO_01279	1.69e-116	-	-	-	S	-	-	-	TraX protein
KIOFINJO_01280	0.000908	-	-	-	S	-	-	-	TraX protein
KIOFINJO_01281	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
KIOFINJO_01283	2.84e-35	dinF	-	-	V	-	-	-	Mate efflux family protein
KIOFINJO_01284	1.7e-95	dinF	-	-	V	-	-	-	Mate efflux family protein
KIOFINJO_01285	3.53e-24	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type enterochelin transport system, periplasmic component
KIOFINJO_01286	2.48e-09	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
KIOFINJO_01287	2.4e-153	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant 1
KIOFINJO_01288	6.92e-187	-	-	-	F	-	-	-	Phosphorylase superfamily
KIOFINJO_01291	2.95e-104	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KIOFINJO_01292	3.95e-24	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KIOFINJO_01293	2.92e-11	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
KIOFINJO_01294	1.38e-250	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Dehydrogenase
KIOFINJO_01295	2.72e-177	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
KIOFINJO_01296	2.11e-69	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
KIOFINJO_01297	9.1e-205	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
KIOFINJO_01298	8.71e-128	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
KIOFINJO_01299	9.28e-15	-	-	-	-	-	-	-	-
KIOFINJO_01300	7.85e-143	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KIOFINJO_01301	2.23e-140	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (Permease
KIOFINJO_01302	8.95e-91	supH	3.1.3.102, 3.1.3.104	-	Q	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	phosphatase activity
KIOFINJO_01303	5.25e-114	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
KIOFINJO_01304	2.04e-255	XK27_12525	-	-	S	-	-	-	hmm pf01594
KIOFINJO_01305	6.76e-39	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	beta-glucosidase activity
KIOFINJO_01306	2.93e-130	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KIOFINJO_01307	6.88e-58	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	beta-glucosidase activity
KIOFINJO_01308	4.17e-50	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KIOFINJO_01309	8.7e-53	-	-	-	S	-	-	-	granule-associated protein
KIOFINJO_01310	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	unusual protein kinase
KIOFINJO_01311	1.43e-111	-	-	-	E	-	-	-	GDSL-like protein
KIOFINJO_01312	5.5e-203	-	-	-	S	-	-	-	Phospholipase, patatin family
KIOFINJO_01313	3.63e-188	dacA1	3.4.16.4	-	M	ko:K01286	-	ko00000,ko01000	Belongs to the peptidase S11 family
KIOFINJO_01314	1.57e-33	dacA1	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
KIOFINJO_01315	2.7e-277	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KIOFINJO_01316	3.23e-162	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KIOFINJO_01317	2.07e-300	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KIOFINJO_01318	9.16e-78	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
KIOFINJO_01319	2.9e-53	-	-	-	P	-	-	-	membrane protein (DUF2207)
KIOFINJO_01320	1.07e-236	acoA	1.2.4.1	-	C	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
KIOFINJO_01321	6.82e-232	acoB	1.2.4.1	-	C	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KIOFINJO_01322	2.12e-275	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KIOFINJO_01323	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
KIOFINJO_01324	2.33e-29	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	GBS Bsp-like repeat
KIOFINJO_01325	1.09e-91	-	3.2.1.17	-	M	ko:K01185,ko:K07273	-	ko00000,ko01000	lysozyme activity
KIOFINJO_01326	1.16e-304	-	-	-	L	-	-	-	Transposase
KIOFINJO_01327	5.71e-201	-	-	-	K	ko:K20374	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
KIOFINJO_01328	2.11e-221	-	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KIOFINJO_01329	8.28e-135	-	-	-	L	-	-	-	nUDIX hydrolase
KIOFINJO_01330	2.04e-13	murA2	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KIOFINJO_01331	1.26e-212	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
KIOFINJO_01332	8.99e-114	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
KIOFINJO_01333	1.48e-82	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase activity
KIOFINJO_01334	2.79e-82	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase activity
KIOFINJO_01335	2.17e-243	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KIOFINJO_01336	1.77e-143	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOFINJO_01337	9.8e-75	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KIOFINJO_01338	3.28e-179	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KIOFINJO_01339	1.03e-202	ilvH	-	-	S	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
KIOFINJO_01340	5.41e-123	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
KIOFINJO_01341	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOFINJO_01342	1.18e-189	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
KIOFINJO_01343	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KIOFINJO_01344	2.41e-15	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	L-ascorbate 6-phosphate lactonase
KIOFINJO_01345	1.98e-157	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
KIOFINJO_01346	1.22e-310	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	COG0168 Trk-type K transport systems, membrane components
KIOFINJO_01347	1.5e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Ribosomal RNA small subunit methyltransferase G
KIOFINJO_01348	7.37e-120	ylbN	-	-	K	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
KIOFINJO_01349	2.69e-158	csrR	-	-	T	-	-	-	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIOFINJO_01350	0.0	covS	-	-	T	-	-	-	Histidine kinase
KIOFINJO_01351	1.46e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KIOFINJO_01352	7.74e-278	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
KIOFINJO_01353	5.34e-214	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
KIOFINJO_01354	1.72e-315	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
KIOFINJO_01355	0.0	-	-	-	P	-	-	-	ABC transporter transmembrane region
KIOFINJO_01357	2.13e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein l17
KIOFINJO_01358	5.37e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KIOFINJO_01359	1.57e-80	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KIOFINJO_01360	4.42e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KIOFINJO_01361	3.26e-22	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
KIOFINJO_01362	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KIOFINJO_01363	2.61e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KIOFINJO_01364	3.68e-294	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KIOFINJO_01365	3.45e-85	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
KIOFINJO_01366	2e-32	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein l30
KIOFINJO_01367	9.94e-104	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KIOFINJO_01368	7.15e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KIOFINJO_01369	1.44e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KIOFINJO_01370	3.78e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KIOFINJO_01371	2.03e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KIOFINJO_01372	5.86e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KIOFINJO_01373	3.99e-64	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KIOFINJO_01374	1.04e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KIOFINJO_01375	7.55e-53	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KIOFINJO_01376	4.36e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
KIOFINJO_01377	3.58e-93	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KIOFINJO_01378	1.1e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KIOFINJO_01379	1.21e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KIOFINJO_01380	8.13e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KIOFINJO_01381	7.19e-196	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KIOFINJO_01382	6e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KIOFINJO_01383	2.13e-135	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
KIOFINJO_01384	2.23e-142	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KIOFINJO_01385	7.41e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
KIOFINJO_01386	1.78e-240	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KIOFINJO_01387	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase
KIOFINJO_01388	2.43e-47	-	-	-	S	-	-	-	MORN repeat protein
KIOFINJO_01389	3.25e-106	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KIOFINJO_01390	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KIOFINJO_01391	3.59e-123	flaR	-	-	F	-	-	-	topology modulation protein
KIOFINJO_01392	3.14e-244	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KIOFINJO_01393	3.96e-253	-	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	Involved in molybdopterin and thiamine biosynthesis, family 2
KIOFINJO_01394	2.73e-172	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPase activity
KIOFINJO_01395	1.23e-160	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
KIOFINJO_01396	3.45e-83	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional
KIOFINJO_01397	5.04e-37	-	-	-	S	-	-	-	overlaps another CDS with the same product name
KIOFINJO_01398	6.53e-138	-	-	-	S	-	-	-	overlaps another CDS with the same product name
KIOFINJO_01399	3.4e-189	XK27_02985	-	-	S	-	-	-	overlaps another CDS with the same product name
KIOFINJO_01400	1.39e-312	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KIOFINJO_01401	1.51e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
KIOFINJO_01402	6.79e-62	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-directed 5'-3' RNA polymerase activity
KIOFINJO_01403	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KIOFINJO_01404	1.55e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KIOFINJO_01405	1.1e-314	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KIOFINJO_01406	7.75e-170	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
KIOFINJO_01407	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
KIOFINJO_01408	4.61e-156	yvqF	-	-	KT	ko:K11622	ko02020,map02020	ko00000,ko00001	membrane
KIOFINJO_01409	4.58e-224	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KIOFINJO_01410	1.29e-99	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KIOFINJO_01413	6.44e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KIOFINJO_01414	5.45e-172	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
KIOFINJO_01415	2.23e-119	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
KIOFINJO_01416	1.21e-106	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
KIOFINJO_01417	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
KIOFINJO_01418	7.27e-206	-	-	-	S	-	-	-	CHAP domain
KIOFINJO_01419	1.65e-305	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
KIOFINJO_01420	2.66e-99	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KIOFINJO_01421	1.03e-261	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KIOFINJO_01422	1.69e-181	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase
KIOFINJO_01423	9.67e-35	-	-	-	-	-	-	-	-
KIOFINJO_01424	3.66e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KIOFINJO_01425	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KIOFINJO_01426	1.36e-90	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
KIOFINJO_01427	5.42e-75	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
KIOFINJO_01428	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KIOFINJO_01429	6.4e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
KIOFINJO_01430	2.17e-81	-	-	-	KT	-	-	-	phosphorelay signal transduction system
KIOFINJO_01432	3.92e-142	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KIOFINJO_01433	4.43e-262	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KIOFINJO_01435	3.08e-134	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KIOFINJO_01436	1.07e-36	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	3-methyladenine DNA glycosylase
KIOFINJO_01437	1.19e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
KIOFINJO_01438	3.79e-254	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KIOFINJO_01439	1.27e-86	spxA_2	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
KIOFINJO_01440	2.9e-26	-	-	-	K	-	-	-	Helix-turn-helix domain
KIOFINJO_01444	9.89e-51	-	-	-	-	-	-	-	-
KIOFINJO_01445	1.74e-52	-	-	-	-	-	-	-	-
KIOFINJO_01446	5.48e-123	-	-	-	L	-	-	-	helicase
KIOFINJO_01447	7.77e-88	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
KIOFINJO_01449	8.21e-99	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
KIOFINJO_01450	2.59e-180	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
KIOFINJO_01451	6.56e-17	XK27_12190	-	-	S	-	-	-	protein conserved in bacteria
KIOFINJO_01453	3.24e-114	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	biotin synthase
KIOFINJO_01454	0.0	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
KIOFINJO_01455	1.5e-229	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
KIOFINJO_01457	6.79e-90	ytxH	-	-	S	-	-	-	General stress protein
KIOFINJO_01458	1.07e-25	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KIOFINJO_01459	4.33e-190	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KIOFINJO_01460	1.42e-218	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KIOFINJO_01461	5.93e-55	WQ51_05770	-	-	KT	-	-	-	PspC domain
KIOFINJO_01462	3.63e-113	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
KIOFINJO_01463	0.0	tex	-	-	K	ko:K06959	-	ko00000	Transcriptional accessory protein
KIOFINJO_01465	2.92e-202	XK27_03015	-	-	S	ko:K07089	-	ko00000	permease
KIOFINJO_01466	2.06e-192	XK27_03010	-	-	S	ko:K08986	-	ko00000	TIGR03943 family
KIOFINJO_01467	2.69e-167	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KIOFINJO_01468	6.62e-53	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KIOFINJO_01469	1.1e-50	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KIOFINJO_01470	7.2e-109	ciaR	-	-	T	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIOFINJO_01471	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
KIOFINJO_01472	6.6e-158	coaB	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	Phosphopantothenate-cysteine ligase
KIOFINJO_01473	2.39e-63	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KIOFINJO_01474	6.2e-46	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KIOFINJO_01475	3.72e-121	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
KIOFINJO_01476	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
KIOFINJO_01477	2.65e-212	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	reductase
KIOFINJO_01478	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KIOFINJO_01480	0.0	pabB	2.6.1.85, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13950	ko00790,map00790	ko00000,ko00001,ko01000,ko01007	component I
KIOFINJO_01481	0.0	-	3.6.3.2, 3.6.3.6, 3.6.3.8	-	P	ko:K01531,ko:K01535,ko:K01537	ko00190,map00190	ko00000,ko00001,ko01000	cation transport ATPase
KIOFINJO_01482	1.98e-40	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	rRNA binding
KIOFINJO_01483	1.22e-222	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
KIOFINJO_01484	1.51e-138	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase small domain protein
KIOFINJO_01485	6.15e-36	pdp	2.4.2.2, 2.4.2.4	-	F	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	ko00000,ko00001,ko01000	phosphorylase activity
KIOFINJO_01486	5.3e-33	pdp	2.4.2.2, 2.4.2.4	-	F	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	ko00000,ko00001,ko01000	phosphorylase activity
KIOFINJO_01487	6.61e-78	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KIOFINJO_01488	6.79e-85	pdp	2.4.2.2, 2.4.2.4	-	F	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	ko00000,ko00001,ko01000	phosphorylase activity
KIOFINJO_01489	9.02e-28	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KIOFINJO_01490	1.32e-83	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KIOFINJO_01491	4.51e-75	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KIOFINJO_01492	1.22e-245	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
KIOFINJO_01493	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KIOFINJO_01494	3.21e-245	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KIOFINJO_01495	1.04e-220	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KIOFINJO_01496	4.54e-157	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
KIOFINJO_01497	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
KIOFINJO_01498	6.64e-38	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
KIOFINJO_01499	3.8e-106	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
KIOFINJO_01500	1.57e-278	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
KIOFINJO_01501	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KIOFINJO_01504	9.42e-242	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KIOFINJO_01505	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KIOFINJO_01506	4.66e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KIOFINJO_01507	4.89e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KIOFINJO_01508	7.65e-185	purR	-	-	F	ko:K09685	-	ko00000,ko03000	operon repressor
KIOFINJO_01509	1.13e-227	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	3'-5' exoribonuclease yhaM
KIOFINJO_01510	4.63e-236	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC domain protein
KIOFINJO_01511	1.92e-153	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
KIOFINJO_01512	2.76e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
KIOFINJO_01513	5.55e-211	rsgA	3.1.3.100	-	G	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KIOFINJO_01515	1.06e-199	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KIOFINJO_01516	1.81e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KIOFINJO_01517	4.49e-185	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	Hydrolase, tatd
KIOFINJO_01518	8.04e-99	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
KIOFINJO_01519	5.36e-68	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
KIOFINJO_01520	1.5e-184	-	-	-	S	-	-	-	Macro domain protein
KIOFINJO_01521	3.24e-14	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	thioesterase
KIOFINJO_01523	2.75e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KIOFINJO_01524	2.17e-35	-	-	-	-	-	-	-	-
KIOFINJO_01525	1.06e-278	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KIOFINJO_01526	5.05e-186	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
KIOFINJO_01527	1.33e-231	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KIOFINJO_01528	1.93e-46	acpP_1	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KIOFINJO_01529	1.5e-167	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
KIOFINJO_01530	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KIOFINJO_01531	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KIOFINJO_01532	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KIOFINJO_01533	5.98e-242	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
KIOFINJO_01534	6.85e-132	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KIOFINJO_01535	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
KIOFINJO_01536	4.98e-96	isp2	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	pathogenesis
KIOFINJO_01537	6.53e-118	-	-	-	L	ko:K07498	-	ko00000	Transposase
KIOFINJO_01538	1.81e-55	capA	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
KIOFINJO_01539	9.29e-138	capA	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein
KIOFINJO_01540	4.9e-72	capA	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein
KIOFINJO_01541	5.05e-52	XK27_08630	-	-	T	ko:K07166	-	ko00000	UPF0237 protein
KIOFINJO_01542	9.68e-309	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
KIOFINJO_01543	4.6e-150	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase
KIOFINJO_01544	5.21e-183	yodJ	3.4.16.4, 3.4.17.14	-	M	ko:K01286,ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
KIOFINJO_01545	2.17e-133	acmA	3.2.1.17	-	NU	ko:K01185,ko:K02395	-	ko00000,ko01000,ko02035	amidase activity
KIOFINJO_01546	4.82e-254	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KIOFINJO_01547	8.45e-107	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KIOFINJO_01548	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
KIOFINJO_01549	8.22e-194	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KIOFINJO_01550	7.45e-179	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KIOFINJO_01551	5.13e-63	thiD	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	phosphomethylpyrimidine kinase
KIOFINJO_01552	3.02e-102	thiD	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	phosphomethylpyrimidine kinase
KIOFINJO_01553	2.97e-82	hmpT	-	-	S	-	-	-	membrane
KIOFINJO_01554	1.93e-122	-	-	-	S	ko:K06889	-	ko00000	thiolester hydrolase activity
KIOFINJO_01555	1.2e-186	-	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
KIOFINJO_01556	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KIOFINJO_01557	6.15e-195	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KIOFINJO_01558	3.93e-99	yhaI	-	-	L	-	-	-	Membrane
KIOFINJO_01559	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
KIOFINJO_01560	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
KIOFINJO_01561	1.72e-141	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KIOFINJO_01562	8.82e-124	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
KIOFINJO_01563	5.86e-68	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KIOFINJO_01564	1.07e-283	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
KIOFINJO_01565	0.0	mapZ	-	-	D	ko:K20073	-	ko00000	Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
KIOFINJO_01566	6.33e-233	-	-	-	L	ko:K07482	-	ko00000	Transposase and inactivated derivatives IS30 family
KIOFINJO_01567	8.57e-177	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
KIOFINJO_01568	2.86e-269	arcT	-	-	E	-	-	-	Aminotransferase
KIOFINJO_01569	1.87e-176	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
KIOFINJO_01570	1.66e-185	XK27_04395	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
KIOFINJO_01571	7.49e-110	XK27_04400	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	Nudix family
KIOFINJO_01572	1.46e-145	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KIOFINJO_01573	1.38e-302	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KIOFINJO_01574	2.41e-74	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
KIOFINJO_01575	1.27e-39	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
KIOFINJO_01576	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type amino acid transport signal transduction systems periplasmic component domain
KIOFINJO_01577	7.15e-176	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOFINJO_01578	1.84e-24	XK27_00735	-	-	-	-	-	-	-
KIOFINJO_01579	1.9e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KIOFINJO_01580	8.41e-11	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
KIOFINJO_01581	2.22e-173	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
KIOFINJO_01584	3.48e-140	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
KIOFINJO_01585	4.33e-69	-	-	-	V	-	-	-	Psort location Cytoplasmic, score
KIOFINJO_01586	4.34e-202	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
KIOFINJO_01587	0.0	-	-	-	C	ko:K06871	-	ko00000	Arylsulfatase regulator (Fe-S oxidoreductase)
KIOFINJO_01588	1.14e-261	-	-	-	V	ko:K06148	-	ko00000,ko02000	(ABC) transporter
KIOFINJO_01589	8.68e-37	-	-	-	V	ko:K06148	-	ko00000,ko02000	(ABC) transporter
KIOFINJO_01591	3.11e-55	-	-	-	S	-	-	-	Domain of unknown function (DUF4299)
KIOFINJO_01592	1.25e-85	-	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	protein possibly involved in aromatic compounds catabolism
KIOFINJO_01593	1.14e-197	-	-	-	EG	-	-	-	Permeases of the drug metabolite transporter (DMT) superfamily
KIOFINJO_01595	1.69e-145	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	phosphoserine phosphatase
KIOFINJO_01596	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KIOFINJO_01597	2.91e-150	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KIOFINJO_01598	1.71e-289	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KIOFINJO_01599	1.07e-141	-	-	-	S	-	-	-	IA, variant 1
KIOFINJO_01600	4.46e-151	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	effector of murein hydrolase
KIOFINJO_01601	5.26e-77	lrgA	-	-	S	ko:K06518	-	ko00000,ko02000	Effector of murein hydrolase LrgA
KIOFINJO_01603	2.92e-78	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
KIOFINJO_01604	3.47e-72	ogt	2.1.1.63, 3.2.2.20	-	L	ko:K00567,ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	methylated-DNA-[protein]-cysteine S-methyltransferase activity
KIOFINJO_01605	2.61e-281	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KIOFINJO_01606	5.63e-136	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
KIOFINJO_01607	3.61e-267	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KIOFINJO_01608	1.7e-149	-	-	-	GK	-	-	-	ROK family
KIOFINJO_01609	1.61e-93	gloA	4.4.1.5	-	E	ko:K01759,ko:K15772	ko00620,ko02010,map00620,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Lactoylglutathione lyase
KIOFINJO_01610	2.63e-157	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	HflC and HflK could regulate a protease
KIOFINJO_01611	1.85e-05	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	HflC and HflK could regulate a protease
KIOFINJO_01612	3.44e-263	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	spermidine putrescine ABC transporter
KIOFINJO_01613	2.44e-169	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component II
KIOFINJO_01614	1.15e-178	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component I
KIOFINJO_01615	7.96e-272	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KIOFINJO_01616	3.1e-219	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
KIOFINJO_01617	1.13e-113	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KIOFINJO_01618	1.05e-81	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KIOFINJO_01619	0.0	amy	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
KIOFINJO_01620	1.29e-188	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KIOFINJO_01621	1.17e-129	folE	3.5.4.16	-	F	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	gtp cyclohydrolase
KIOFINJO_01622	0.0	ydaO	-	-	E	-	-	-	amino acid
KIOFINJO_01623	2.35e-305	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
KIOFINJO_01624	9.09e-50	ylqC	-	-	L	ko:K06960	-	ko00000	Belongs to the UPF0109 family
KIOFINJO_01625	1.87e-57	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
KIOFINJO_01626	5.38e-219	tehB	2.1.1.265	-	PQ	ko:K16868	-	ko00000,ko01000	tellurite resistance protein tehb
KIOFINJO_01627	2.43e-202	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
KIOFINJO_01628	1.22e-97	-	-	-	S	-	-	-	QueT transporter
KIOFINJO_01629	2.33e-155	-	-	-	L	-	-	-	Transposase DDE domain
KIOFINJO_01630	3.86e-237	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KIOFINJO_01631	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KIOFINJO_01632	2.79e-111	ccl	-	-	S	-	-	-	cog cog4708
KIOFINJO_01633	2.35e-205	rbn	-	-	E	ko:K07058	-	ko00000	Belongs to the UPF0761 family
KIOFINJO_01634	2.86e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
KIOFINJO_01635	6.58e-296	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
KIOFINJO_01636	5.58e-126	XK27_07830	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase GNAT Family
KIOFINJO_01637	2.59e-296	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KIOFINJO_01638	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
KIOFINJO_01639	4.12e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
KIOFINJO_01640	1.76e-183	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
KIOFINJO_01641	3.54e-117	nodB3	-	-	G	-	-	-	polysaccharide deacetylase
KIOFINJO_01642	7.67e-66	nodB3	-	-	G	-	-	-	polysaccharide deacetylase
KIOFINJO_01643	6.12e-181	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase
KIOFINJO_01644	4.12e-56	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
KIOFINJO_01645	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KIOFINJO_01646	6.14e-205	corA	-	-	P	-	-	-	CorA-like protein
KIOFINJO_01647	1.07e-82	yjqA	-	-	S	-	-	-	Bacterial PH domain
KIOFINJO_01648	4.57e-129	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter
KIOFINJO_01649	2.62e-203	rgg	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
KIOFINJO_01650	5.97e-188	yjbB	-	-	G	-	-	-	Permeases of the major facilitator superfamily
KIOFINJO_01651	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KIOFINJO_01652	1.15e-155	ywaF	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
KIOFINJO_01653	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KIOFINJO_01656	9.46e-200	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
KIOFINJO_01657	2.01e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOFINJO_01658	1.4e-148	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter (Permease
KIOFINJO_01659	8.58e-149	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter (Permease
KIOFINJO_01660	1.12e-246	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
KIOFINJO_01661	9.48e-43	copZ	-	-	P	-	-	-	Heavy metal-associated domain protein
KIOFINJO_01662	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
KIOFINJO_01663	3.66e-98	copY	-	-	K	-	-	-	negative regulation of transcription, DNA-templated
KIOFINJO_01664	1.23e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KIOFINJO_01665	2.76e-288	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KIOFINJO_01666	3.9e-131	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the TrpF family
KIOFINJO_01667	7.94e-173	trpC	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
KIOFINJO_01668	3.86e-210	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KIOFINJO_01669	2.47e-136	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	anthranilate
KIOFINJO_01670	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KIOFINJO_01671	3.63e-57	MA20_20425	2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5	-	E	ko:K00800,ko:K03785,ko:K04092,ko:K04782	ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
KIOFINJO_01672	1.25e-74	-	-	-	-	-	-	-	-
KIOFINJO_01673	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
KIOFINJO_01674	3.83e-35	-	-	-	-	-	-	-	-
KIOFINJO_01675	5.31e-59	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KIOFINJO_01676	2.2e-61	-	-	-	L	-	-	-	transposase activity
KIOFINJO_01677	1.4e-40	-	-	-	K	-	-	-	transcriptional regulator, MerR family
KIOFINJO_01678	1.31e-135	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
KIOFINJO_01679	1.41e-80	WQ51_02910	-	-	S	-	-	-	Protein of unknown function, DUF536
KIOFINJO_01680	1.23e-82	XK27_02560	-	-	S	-	-	-	cog cog2151
KIOFINJO_01681	0.0	ilvD	4.2.1.9	-	E	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
KIOFINJO_01682	3.35e-289	ytfP	-	-	S	ko:K07007	-	ko00000	Flavoprotein
KIOFINJO_01684	4.36e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KIOFINJO_01685	8.46e-197	ytmP	-	-	M	-	-	-	Phosphotransferase
KIOFINJO_01686	2.57e-230	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
KIOFINJO_01687	1.5e-171	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
KIOFINJO_01688	2.93e-93	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KIOFINJO_01689	2.23e-13	-	-	-	-	-	-	-	-
KIOFINJO_01690	4.85e-143	-	-	-	-	-	-	-	-
KIOFINJO_01691	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	ATP-dependent Clp protease ATP-binding subunit
KIOFINJO_01692	1.46e-261	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
KIOFINJO_01693	3.24e-178	XK27_06665	-	-	Q	-	-	-	Methyltransferase domain protein
KIOFINJO_01694	9.81e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KIOFINJO_01695	2.01e-139	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
KIOFINJO_01696	1.11e-152	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KIOFINJO_01697	1.59e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
KIOFINJO_01698	2.78e-275	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KIOFINJO_01699	1.84e-127	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
KIOFINJO_01700	8.57e-197	-	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KIOFINJO_01701	1.02e-85	-	-	-	-	-	-	-	-
KIOFINJO_01702	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KIOFINJO_01703	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KIOFINJO_01704	7.49e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KIOFINJO_01705	4.51e-35	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
KIOFINJO_01706	3.8e-43	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
KIOFINJO_01707	1.85e-120	ascB	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KIOFINJO_01708	1.12e-190	ascB	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KIOFINJO_01709	3.96e-125	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KIOFINJO_01710	8.06e-198	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
KIOFINJO_01711	3.02e-130	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	isochorismatase
KIOFINJO_01712	6.34e-182	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KIOFINJO_01713	3.71e-303	aspC	2.6.1.2, 2.6.1.66	-	E	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
KIOFINJO_01714	7.54e-99	XK27_03180	-	-	T	-	-	-	universal stress protein
KIOFINJO_01716	6.98e-202	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KIOFINJO_01717	2.02e-304	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	COG1253 Hemolysins and related proteins containing CBS domains
KIOFINJO_01718	1.29e-185	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOFINJO_01719	0.0	nhaP1	-	-	P	ko:K03316	-	ko00000	NhaP-type Na H and K H antiporters
KIOFINJO_01721	1.82e-126	mraW1	-	-	J	-	-	-	(SAM)-dependent
KIOFINJO_01722	1.51e-236	ytqA	-	-	S	ko:K07139	-	ko00000	radical SAM protein
KIOFINJO_01723	1.61e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
KIOFINJO_01724	7.91e-115	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KIOFINJO_01725	9.01e-121	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
KIOFINJO_01726	4.78e-220	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KIOFINJO_01727	3.45e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF4059)
KIOFINJO_01728	3.38e-170	tcyN	3.6.3.21	-	E	ko:K02028,ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOFINJO_01729	1.37e-221	yxeN	-	-	P	ko:K02029,ko:K16959,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOFINJO_01730	1.12e-191	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC-type amino acid transport signal transduction systems, periplasmic component domain
KIOFINJO_01732	8.1e-261	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KIOFINJO_01733	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	formate acetyltransferase'
KIOFINJO_01734	1.35e-156	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	carbonic anhydrase
KIOFINJO_01735	1.49e-48	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KIOFINJO_01736	5.76e-44	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KIOFINJO_01737	2.05e-59	hsdS_1	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
KIOFINJO_01738	7.75e-44	-	-	-	D	-	-	-	nuclear chromosome segregation
KIOFINJO_01739	6.36e-105	-	-	-	L	ko:K04763	-	ko00000,ko03036	DNA integration
KIOFINJO_01740	3.03e-159	XK27_05540	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
KIOFINJO_01741	7e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
KIOFINJO_01742	7.19e-152	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
KIOFINJO_01743	1.19e-35	-	-	-	-	-	-	-	-
KIOFINJO_01744	4.14e-235	-	-	-	V	-	-	-	COG1680 Beta-lactamase class C and other penicillin binding proteins
KIOFINJO_01745	6.61e-179	cppA	-	-	E	-	-	-	CppA N-terminal
KIOFINJO_01746	6.33e-233	-	-	-	L	ko:K07482	-	ko00000	Transposase and inactivated derivatives IS30 family
KIOFINJO_01747	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
KIOFINJO_01748	8.03e-91	-	-	-	K	ko:K22103	-	ko00000,ko03000	transcriptional regulator (DeoR family)
KIOFINJO_01749	2.46e-50	-	-	-	K	ko:K22103	-	ko00000,ko03000	transcriptional regulator (DeoR family)
KIOFINJO_01750	3.96e-49	cof	-	-	Q	-	-	-	phosphatase activity
KIOFINJO_01751	2.86e-74	cof	-	-	Q	-	-	-	phosphatase activity
KIOFINJO_01752	2.28e-110	-	3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27	-	I	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
KIOFINJO_01753	2.8e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
KIOFINJO_01754	1.27e-34	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Belongs to the SecE SEC61-gamma family
KIOFINJO_01755	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
KIOFINJO_01756	5.78e-213	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
KIOFINJO_01757	1.15e-39	-	-	-	J	-	-	-	TM2 domain
KIOFINJO_01758	1.35e-56	-	-	-	-	-	-	-	-
KIOFINJO_01761	9.7e-298	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
KIOFINJO_01762	2.36e-73	amd	-	-	E	-	-	-	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KIOFINJO_01764	1.04e-171	-	-	-	L	-	-	-	Transposase
KIOFINJO_01766	1.34e-172	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
KIOFINJO_01767	7.46e-178	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
KIOFINJO_01768	3.07e-169	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
KIOFINJO_01769	9.01e-75	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
KIOFINJO_01770	3.15e-175	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
KIOFINJO_01771	5.16e-272	nirJ	-	-	C	ko:K06139,ko:K22227	-	ko00000	radical SAM domain protein
KIOFINJO_01774	4.16e-199	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
KIOFINJO_01775	3.71e-57	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-Shock Protein
KIOFINJO_01776	2.63e-44	-	-	-	K	-	-	-	Cold shock protein domain
KIOFINJO_01777	4.41e-55	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	dipeptidase activity
KIOFINJO_01778	5.22e-117	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KIOFINJO_01779	1.2e-207	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
KIOFINJO_01780	2.6e-233	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
KIOFINJO_01781	2.08e-209	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
KIOFINJO_01782	3.26e-177	yejC	-	-	S	-	-	-	cyclic nucleotide-binding protein
KIOFINJO_01783	4.9e-24	-	-	-	D	-	-	-	nuclear chromosome segregation
KIOFINJO_01784	4.7e-123	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
KIOFINJO_01785	7.78e-176	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KIOFINJO_01786	3.49e-107	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
KIOFINJO_01787	1.58e-160	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KIOFINJO_01788	1.84e-83	aldR	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
KIOFINJO_01795	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KIOFINJO_01796	1.46e-300	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
KIOFINJO_01797	4.88e-49	XK27_02060	-	-	S	-	-	-	Transglycosylase associated protein
KIOFINJO_01798	1.44e-72	badR	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
KIOFINJO_01799	1.13e-125	XK27_03570	-	-	S	ko:K19784	-	ko00000	reductase
KIOFINJO_01800	1.29e-44	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
KIOFINJO_01801	2.39e-207	-	-	-	EGP	-	-	-	Transmembrane secretion effector
KIOFINJO_01802	6.6e-42	-	-	-	EGP	-	-	-	Transmembrane secretion effector
KIOFINJO_01803	3.75e-100	-	-	-	F	-	-	-	NUDIX domain
KIOFINJO_01804	4.98e-231	-	-	-	F	-	-	-	NUDIX domain
KIOFINJO_01805	0.0	-	-	-	Q	-	-	-	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KIOFINJO_01806	8.41e-260	amiE	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KIOFINJO_01807	2.01e-213	amiD	-	-	P	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOFINJO_01808	7.6e-31	amiC	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOFINJO_01809	1.87e-306	amiC	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOFINJO_01810	0.0	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
KIOFINJO_01811	3.74e-38	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
KIOFINJO_01812	7.59e-212	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
KIOFINJO_01813	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KIOFINJO_01815	2.76e-111	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
KIOFINJO_01816	1.12e-66	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
KIOFINJO_01817	8.98e-194	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
KIOFINJO_01818	7.37e-80	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine acetyltransferase
KIOFINJO_01820	6.82e-16	-	-	-	H	-	-	-	gamma-glutamylcysteine synthetase
KIOFINJO_01821	2.3e-20	-	-	-	H	-	-	-	gamma-glutamylcysteine synthetase
KIOFINJO_01822	7.87e-144	-	6.3.2.2	-	H	ko:K01919,ko:K06048	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	ergothioneine biosynthetic process
KIOFINJO_01824	9.95e-211	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	aldolase
KIOFINJO_01825	0.0	copB	3.6.3.4	-	P	ko:K01533	-	ko00000,ko01000	P-type ATPase
KIOFINJO_01826	1.35e-282	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
KIOFINJO_01827	2.03e-250	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
KIOFINJO_01828	1.53e-212	-	-	-	L	ko:K07497	-	ko00000	integrase core domain
KIOFINJO_01829	1.86e-67	-	-	-	L	-	-	-	Transposase
KIOFINJO_01830	7.69e-18	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
KIOFINJO_01831	1.64e-98	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
KIOFINJO_01832	2.58e-113	-	-	-	L	-	-	-	Transposase
KIOFINJO_01833	0.0	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
KIOFINJO_01834	1.49e-54	-	-	-	V	ko:K18996,ko:K19171	-	ko00000,ko02048,ko03032	(ABC) transporter
KIOFINJO_01835	4.12e-98	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
KIOFINJO_01836	1.32e-97	zmpB	-	-	M	ko:K08643	-	ko00000,ko01000,ko01002	M26 IgA1-specific Metallo-endopeptidase C-terminal region
KIOFINJO_01837	5.97e-253	-	-	-	M	ko:K08643	-	ko00000,ko01000,ko01002	translation initiation factor activity
KIOFINJO_01838	1.18e-34	-	-	-	L	ko:K07497	-	ko00000	transposition
KIOFINJO_01839	1.7e-13	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
KIOFINJO_01840	1.4e-236	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
KIOFINJO_01841	3.3e-282	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KIOFINJO_01842	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDPglucose--hexose-1-phosphate uridylyltransferase
KIOFINJO_01843	6.03e-248	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
KIOFINJO_01844	1.69e-257	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
KIOFINJO_01845	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	transporter
KIOFINJO_01846	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
KIOFINJO_01847	2.27e-293	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KIOFINJO_01848	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	ATPase involved in DNA repair
KIOFINJO_01850	2.96e-14	-	-	-	-	-	-	-	-
KIOFINJO_01851	0.0	-	-	-	M	-	-	-	family 8
KIOFINJO_01852	1.96e-12	-	-	-	-	-	-	-	-
KIOFINJO_01853	6.23e-11	-	-	-	-	-	-	-	-
KIOFINJO_01854	4.88e-140	-	-	-	E	-	-	-	LysE type translocator
KIOFINJO_01856	1.08e-14	-	-	-	IQ	-	-	-	PFAM AMP-dependent synthetase and ligase
KIOFINJO_01857	1.63e-150	-	-	-	-	-	-	-	-
KIOFINJO_01858	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KIOFINJO_01859	8.65e-81	-	-	-	-	-	-	-	-
KIOFINJO_01861	7.54e-83	-	-	-	S	-	-	-	Signal peptide protein, YSIRK family
KIOFINJO_01862	7.28e-70	saeR	-	-	K	ko:K10682	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
KIOFINJO_01863	1.58e-50	BP1961	-	-	P	-	-	-	nitric oxide dioxygenase activity
KIOFINJO_01865	0.0	XK27_07020	-	-	S	-	-	-	Belongs to the UPF0371 family
KIOFINJO_01866	1.29e-158	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
KIOFINJO_01867	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
KIOFINJO_01868	1.68e-180	-	-	-	S	-	-	-	Abortive infection C-terminus
KIOFINJO_01869	4.11e-12	-	-	-	-	-	-	-	-
KIOFINJO_01870	7.36e-70	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
KIOFINJO_01871	1.11e-203	yvgN	-	-	C	-	-	-	reductase
KIOFINJO_01872	1.23e-06	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
KIOFINJO_01873	9.58e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
KIOFINJO_01874	1.42e-143	ydgI	-	-	C	-	-	-	Nitroreductase
KIOFINJO_01875	6.14e-297	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KIOFINJO_01876	1.84e-203	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KIOFINJO_01877	2.96e-100	ywnA_2	-	-	K	-	-	-	Transcriptional regulator
KIOFINJO_01878	1.08e-118	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
KIOFINJO_01879	2.85e-141	XK27_02070	-	-	S	ko:K07078	-	ko00000	nitroreductase
KIOFINJO_01880	4.6e-294	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
KIOFINJO_01881	3.31e-35	csbD	-	-	K	-	-	-	CsbD-like
KIOFINJO_01882	1.4e-65	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
KIOFINJO_01883	1.39e-88	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
KIOFINJO_01884	8.11e-299	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
KIOFINJO_01885	5.65e-231	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KIOFINJO_01887	3.03e-63	-	-	-	C	ko:K08317	-	ko00000,ko01000	glycerol dehydrogenase
KIOFINJO_01888	1.61e-51	-	-	-	C	ko:K08317	-	ko00000,ko01000	glycerol dehydrogenase
KIOFINJO_01889	2.11e-187	ykrV3	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	mutations do not affect methionine salvage in vivo however
KIOFINJO_01890	3.99e-141	-	-	-	S	-	-	-	MmgE/PrpD family
KIOFINJO_01891	7.54e-58	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KIOFINJO_01892	8.13e-93	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOFINJO_01893	2.66e-118	yxeO	-	-	E	ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
KIOFINJO_01894	1.9e-250	-	4.3.2.2, 5.5.1.2	-	F	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase
KIOFINJO_01895	1.04e-115	yxeM	-	-	ET	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
KIOFINJO_01896	2.01e-241	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KIOFINJO_01897	1.2e-315	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
KIOFINJO_01898	3.14e-46	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
KIOFINJO_01899	9.96e-97	pbuX	-	-	F	ko:K16169	-	ko00000,ko02000	xanthine permease
KIOFINJO_01900	4.61e-97	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
KIOFINJO_01901	3.72e-87	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KIOFINJO_01902	1.29e-159	graR	-	-	KT	ko:K19082	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIOFINJO_01903	4.75e-220	-	-	-	T	-	-	-	Histidine kinase
KIOFINJO_01904	3e-171	yxdL	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
KIOFINJO_01905	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
KIOFINJO_01906	6.33e-46	XK27_05000	-	-	S	ko:K06940	-	ko00000	metal cluster binding
KIOFINJO_01907	5.54e-105	-	-	-	F	-	-	-	cytidine deaminase activity
KIOFINJO_01908	2.73e-213	yocS	-	-	S	ko:K03453	-	ko00000	Transporter
KIOFINJO_01911	1.52e-205	XK27_09825	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
KIOFINJO_01912	8.66e-172	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
KIOFINJO_01913	1.75e-238	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KIOFINJO_01914	7.23e-135	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KIOFINJO_01915	1.21e-128	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	transport system, permease component
KIOFINJO_01916	3.09e-45	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	transport system, permease component
KIOFINJO_01917	2.06e-188	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
KIOFINJO_01919	2.03e-192	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
KIOFINJO_01920	8.06e-158	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
KIOFINJO_01921	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KIOFINJO_01922	1.2e-262	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
KIOFINJO_01923	0.0	-	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
KIOFINJO_01924	1.09e-143	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
KIOFINJO_01925	3.49e-217	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
KIOFINJO_01926	2.69e-178	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
KIOFINJO_01927	6.45e-124	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KIOFINJO_01928	7.3e-85	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	biotin transmembrane transporter activity
KIOFINJO_01929	6.13e-91	yfnB	3.8.1.2	-	E	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	hydrolase
KIOFINJO_01930	1.85e-48	yfnB	3.8.1.2	-	E	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	hydrolase
KIOFINJO_01931	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KIOFINJO_01932	7.61e-309	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol