ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HCBKCGNC_00001 9.92e-33 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HCBKCGNC_00002 2.09e-89 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCBKCGNC_00003 8.05e-91 - - - O - - - ADP-ribosylglycohydrolase
HCBKCGNC_00005 4.26e-108 - - - C - - - Domain of unknown function (DUF4931)
HCBKCGNC_00006 7.86e-116 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HCBKCGNC_00007 6.35e-66 - - - M - - - LysM domain protein
HCBKCGNC_00008 1.13e-24 - - - P - - - Rhodanese Homology Domain
HCBKCGNC_00009 3.05e-48 - - - M - - - LysM domain
HCBKCGNC_00010 2.32e-203 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
HCBKCGNC_00011 1.06e-243 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
HCBKCGNC_00012 5.29e-178 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
HCBKCGNC_00013 1.34e-254 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HCBKCGNC_00014 4.26e-277 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter transmembrane region
HCBKCGNC_00015 4.59e-121 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HCBKCGNC_00016 1.73e-134 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HCBKCGNC_00017 2.53e-196 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HCBKCGNC_00018 1.84e-183 pbuO_1 - - S ko:K06901 - ko00000,ko02000 Permease family
HCBKCGNC_00020 4.46e-37 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
HCBKCGNC_00021 2.76e-163 ydaJ - - G - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
HCBKCGNC_00022 4.64e-238 - - - - - - - -
HCBKCGNC_00023 5.19e-257 - - - S - - - Protein conserved in bacteria
HCBKCGNC_00024 1.72e-255 ydaM - - M - - - Glycosyl transferase family group 2
HCBKCGNC_00025 0.0 - - - S - - - Bacterial cellulose synthase subunit
HCBKCGNC_00026 1.32e-152 - - - T - - - diguanylate cyclase activity
HCBKCGNC_00027 6.02e-37 - - - T - - - Putative diguanylate phosphodiesterase
HCBKCGNC_00028 2.41e-65 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HCBKCGNC_00029 0.0 - - - L - - - Helicase C-terminal domain protein
HCBKCGNC_00030 0.0 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HCBKCGNC_00031 2.74e-69 - - - S - - - Membrane
HCBKCGNC_00032 1.19e-79 - - - K - - - helix_turn_helix, arabinose operon control protein
HCBKCGNC_00034 5.3e-265 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HCBKCGNC_00035 5.92e-33 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
HCBKCGNC_00036 5.68e-240 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HCBKCGNC_00037 2.34e-77 yokL3 - - J - - - Acetyltransferase (GNAT) domain
HCBKCGNC_00038 5.02e-144 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HCBKCGNC_00039 1.84e-104 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HCBKCGNC_00040 1.17e-81 - - - - - - - -
HCBKCGNC_00041 1.69e-225 rsmF - - J - - - NOL1 NOP2 sun family protein
HCBKCGNC_00042 1.44e-53 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HCBKCGNC_00043 9.81e-61 - - - M - - - Chain length determinant protein
HCBKCGNC_00044 1.41e-82 - - - D - - - AAA domain
HCBKCGNC_00045 1.66e-276 capD - - M - - - Psort location CytoplasmicMembrane, score
HCBKCGNC_00046 2.49e-209 epsN - - M ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
HCBKCGNC_00047 4.04e-99 - - - M ko:K13012 - ko00000,ko01005 Bacterial sugar transferase
HCBKCGNC_00048 7.87e-25 - - - S ko:K19429 - ko00000,ko01000 Bacterial transferase hexapeptide (six repeats)
HCBKCGNC_00049 4.68e-38 - - - GM ko:K13006,ko:K19429 - ko00000,ko01000,ko01005 COG0110 Acetyltransferase (isoleucine patch superfamily)
HCBKCGNC_00050 3.26e-152 - - - M - - - Glycosyl transferases group 1
HCBKCGNC_00051 9.03e-97 - - - M - - - glycosyl transferase group 1
HCBKCGNC_00052 1.29e-75 - - - M - - - Glycosyltransferase Family 4
HCBKCGNC_00053 1.02e-46 - - GT2 S ko:K12990 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyltransferase
HCBKCGNC_00054 4.01e-72 - - - M - - - Glycosyltransferase like family 2
HCBKCGNC_00055 1.21e-08 - - - S - - - EpsG family
HCBKCGNC_00056 5.39e-63 - - - - - - - -
HCBKCGNC_00057 9.65e-147 - - - S - - - Glycosyltransferase WbsX
HCBKCGNC_00058 1.36e-74 - - - M - - - Glycosyl transferases group 1
HCBKCGNC_00059 5.3e-126 - - - S - - - Psort location CytoplasmicMembrane, score
HCBKCGNC_00060 1.87e-184 - 5.1.3.6 - GM ko:K08679 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 RmlD substrate binding domain
HCBKCGNC_00061 3.52e-225 - 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HCBKCGNC_00062 4.57e-79 - - - M - - - Glycosyl transferases group 1
HCBKCGNC_00063 2.66e-156 - - - M - - - Glycosyl transferases group 1
HCBKCGNC_00066 8.23e-105 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
HCBKCGNC_00067 7.27e-53 ywnA - - K - - - Transcriptional regulator
HCBKCGNC_00068 2.25e-39 - - - S - - - CHY zinc finger
HCBKCGNC_00069 3.76e-106 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
HCBKCGNC_00070 2.29e-51 ybbB - - S - - - Protein of unknown function (DUF1211)
HCBKCGNC_00071 2.27e-29 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
HCBKCGNC_00073 1.37e-52 - - - M - - - Acetyltransferase (GNAT) family
HCBKCGNC_00074 6.67e-90 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
HCBKCGNC_00075 3.37e-81 - - - H - - - Methyltransferase domain
HCBKCGNC_00082 3.02e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HCBKCGNC_00083 1.55e-37 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
HCBKCGNC_00084 4.7e-57 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HCBKCGNC_00085 1.51e-09 - - - M - - - LysM domain
HCBKCGNC_00088 2.1e-91 - - - - - - - -
HCBKCGNC_00089 1.94e-124 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HCBKCGNC_00090 1.56e-225 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HCBKCGNC_00091 3.63e-155 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
HCBKCGNC_00092 4.03e-102 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HCBKCGNC_00093 6.04e-275 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HCBKCGNC_00094 6.85e-49 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCBKCGNC_00095 1.58e-74 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HCBKCGNC_00096 3.83e-79 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HCBKCGNC_00097 2.3e-127 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HCBKCGNC_00098 8.84e-76 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HCBKCGNC_00099 7.83e-56 - - - S - - - Protein of unknown function (DUF441)
HCBKCGNC_00100 3.06e-159 yitL - - S ko:K00243 - ko00000 S1 domain
HCBKCGNC_00101 3.17e-143 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
HCBKCGNC_00102 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
HCBKCGNC_00103 1.17e-98 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HCBKCGNC_00104 6.51e-238 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HCBKCGNC_00105 1.13e-83 ypsA - - S - - - Belongs to the UPF0398 family
HCBKCGNC_00106 3.95e-244 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Adenine deaminase C-terminal domain
HCBKCGNC_00108 8.4e-94 - - - M - - - GNAT acetyltransferase
HCBKCGNC_00109 1.2e-87 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HCBKCGNC_00110 6.25e-72 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HCBKCGNC_00111 3.91e-28 - - - F - - - Hydrolase of X-linked nucleoside diphosphate N terminal
HCBKCGNC_00113 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
HCBKCGNC_00114 3.4e-259 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
HCBKCGNC_00115 3.07e-162 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HCBKCGNC_00116 2.31e-167 - - - L - - - Belongs to the 'phage' integrase family
HCBKCGNC_00117 9.38e-83 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain protein
HCBKCGNC_00118 5.62e-76 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain protein
HCBKCGNC_00119 4.82e-89 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCBKCGNC_00120 1.33e-135 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
HCBKCGNC_00121 4.84e-92 - - - K - - - Transcriptional regulator
HCBKCGNC_00122 5.29e-157 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
HCBKCGNC_00123 2.03e-144 - - - EGP ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
HCBKCGNC_00124 4.75e-215 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HCBKCGNC_00125 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HCBKCGNC_00126 2.93e-262 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HCBKCGNC_00127 7.63e-237 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HCBKCGNC_00129 1.25e-108 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HCBKCGNC_00130 3.3e-52 - - - - - - - -
HCBKCGNC_00131 4.53e-151 icaA - - M - - - Glycosyl transferase family group 2
HCBKCGNC_00132 3.42e-59 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
HCBKCGNC_00133 6.24e-277 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HCBKCGNC_00134 5.38e-77 - - - S - - - Helix-turn-helix domain
HCBKCGNC_00135 2.83e-157 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HCBKCGNC_00136 1.79e-27 - - - M - - - Lysin motif
HCBKCGNC_00137 1.02e-111 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HCBKCGNC_00138 1.71e-105 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Ami_3
HCBKCGNC_00139 2.07e-196 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
HCBKCGNC_00140 2.42e-88 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HCBKCGNC_00141 5.92e-40 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HCBKCGNC_00142 5.4e-198 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HCBKCGNC_00143 2.72e-114 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HCBKCGNC_00145 1.25e-275 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCBKCGNC_00146 1.94e-222 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
HCBKCGNC_00147 4.73e-40 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCBKCGNC_00148 3.32e-191 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HCBKCGNC_00149 3.34e-76 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Low molecular weight phosphatase family
HCBKCGNC_00150 3.19e-220 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HCBKCGNC_00151 1.17e-288 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HCBKCGNC_00152 2.02e-48 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HCBKCGNC_00154 2.83e-26 - - - K - - - Psort location Cytoplasmic, score
HCBKCGNC_00155 3.45e-142 natA - - S ko:K01990 - ko00000,ko00002,ko02000 Domain of unknown function (DUF4162)
HCBKCGNC_00156 5.32e-104 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-type Na efflux pump, permease component
HCBKCGNC_00157 1.47e-116 - - - EG - - - EamA-like transporter family
HCBKCGNC_00158 1.42e-98 - - - S - - - Calcineurin-like phosphoesterase
HCBKCGNC_00159 4.33e-235 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HCBKCGNC_00160 3.4e-53 - - - S - - - ASCH
HCBKCGNC_00161 6.76e-92 - 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase, peptidase S26
HCBKCGNC_00162 4.15e-148 - - - S - - - EDD domain protein, DegV family
HCBKCGNC_00163 2.07e-52 - - - K - - - Transcriptional regulator
HCBKCGNC_00164 1.84e-246 FbpA - - K - - - Fibronectin-binding protein
HCBKCGNC_00165 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCBKCGNC_00166 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCBKCGNC_00167 1.38e-106 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HCBKCGNC_00168 6.49e-53 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
HCBKCGNC_00170 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HCBKCGNC_00171 1.7e-211 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HCBKCGNC_00172 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HCBKCGNC_00173 6.47e-21 - - - S - - - Protein of unknown function (DUF2929)
HCBKCGNC_00174 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HCBKCGNC_00175 5.64e-256 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HCBKCGNC_00176 5.49e-54 XK27_04120 - - S - - - Putative amino acid metabolism
HCBKCGNC_00177 6.7e-201 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HCBKCGNC_00178 7.27e-119 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HCBKCGNC_00180 1.21e-104 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HCBKCGNC_00181 4.92e-165 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HCBKCGNC_00182 1.34e-220 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HCBKCGNC_00183 1.24e-173 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HCBKCGNC_00184 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HCBKCGNC_00185 2.21e-256 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HCBKCGNC_00186 2.75e-190 XK27_05225 - - S - - - Tetratricopeptide repeat protein
HCBKCGNC_00187 1.72e-174 - - - EG - - - EamA-like transporter family
HCBKCGNC_00188 6.31e-93 - - - L - - - DNA alkylation repair enzyme
HCBKCGNC_00189 1.76e-232 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HCBKCGNC_00190 3.83e-130 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HCBKCGNC_00191 6.85e-98 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HCBKCGNC_00192 8.31e-185 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
HCBKCGNC_00195 8.73e-51 - - - - - - - -
HCBKCGNC_00196 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HCBKCGNC_00197 1.46e-34 - - - S - - - Family of unknown function (DUF5322)
HCBKCGNC_00198 8.9e-48 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
HCBKCGNC_00199 9.38e-219 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HCBKCGNC_00200 3.6e-57 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HCBKCGNC_00202 3.49e-111 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HCBKCGNC_00203 4.06e-218 araT1 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HCBKCGNC_00204 2.33e-147 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
HCBKCGNC_00205 5.38e-185 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
HCBKCGNC_00206 3.17e-173 - - - K - - - Transcriptional regulator
HCBKCGNC_00207 3.01e-114 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HCBKCGNC_00208 6.09e-109 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HCBKCGNC_00209 1.82e-238 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HCBKCGNC_00210 1.29e-141 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HCBKCGNC_00211 7.51e-257 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
HCBKCGNC_00212 2.49e-97 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HCBKCGNC_00213 1.19e-164 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HCBKCGNC_00214 3.83e-56 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HCBKCGNC_00215 1.27e-72 yjcF - - J - - - HAD-hyrolase-like
HCBKCGNC_00216 2.53e-71 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HCBKCGNC_00217 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HCBKCGNC_00218 2.49e-96 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HCBKCGNC_00219 3.09e-149 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
HCBKCGNC_00220 5.19e-56 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
HCBKCGNC_00221 1.01e-182 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
HCBKCGNC_00222 5.6e-17 - - - - - - - -
HCBKCGNC_00223 2e-88 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCBKCGNC_00224 4.31e-127 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HCBKCGNC_00225 1.15e-163 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HCBKCGNC_00226 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCBKCGNC_00227 7.45e-220 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HCBKCGNC_00228 3.97e-56 yodB - - K - - - Transcriptional regulator, HxlR family
HCBKCGNC_00229 1.95e-88 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HCBKCGNC_00230 5.71e-110 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCBKCGNC_00233 8.63e-20 - - - - - - - -
HCBKCGNC_00235 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HCBKCGNC_00236 2.03e-48 - - - S - - - repeat protein
HCBKCGNC_00237 4.16e-129 pgm - - G - - - Phosphoglycerate mutase family
HCBKCGNC_00238 2.05e-255 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
HCBKCGNC_00239 6.46e-165 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HCBKCGNC_00240 1.17e-105 - - - K - - - Bacterial regulatory proteins, tetR family
HCBKCGNC_00241 6.67e-257 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
HCBKCGNC_00242 1.16e-263 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HCBKCGNC_00243 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCBKCGNC_00244 1.96e-106 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
HCBKCGNC_00245 1.67e-123 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCBKCGNC_00246 2.54e-170 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HCBKCGNC_00247 1.77e-33 yozE - - S - - - Belongs to the UPF0346 family
HCBKCGNC_00248 7.98e-69 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
HCBKCGNC_00249 3.49e-98 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
HCBKCGNC_00251 5.16e-135 ydhF - - S - - - Aldo keto reductase
HCBKCGNC_00252 1.83e-31 - - - K - - - Transcriptional regulator
HCBKCGNC_00253 5.11e-171 - - - C - - - Aldo keto reductase
HCBKCGNC_00254 7.52e-74 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HCBKCGNC_00255 1.36e-200 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HCBKCGNC_00256 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
HCBKCGNC_00257 5.86e-167 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HCBKCGNC_00258 1.85e-136 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HCBKCGNC_00259 1.89e-142 ypjC - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCBKCGNC_00260 5.44e-87 - - - L - - - Phage integrase, N-terminal SAM-like domain
HCBKCGNC_00262 1.87e-75 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
HCBKCGNC_00263 5.93e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HCBKCGNC_00264 1.7e-147 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HCBKCGNC_00267 1.25e-125 - - - M - - - Glycosyltransferase like family 2
HCBKCGNC_00268 6.04e-107 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
HCBKCGNC_00269 3.38e-116 - - - M - - - transferase activity, transferring glycosyl groups
HCBKCGNC_00270 4.35e-160 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCBKCGNC_00271 4.23e-100 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCBKCGNC_00272 1.26e-107 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HCBKCGNC_00273 8.09e-72 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
HCBKCGNC_00274 6.95e-300 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HCBKCGNC_00275 2.59e-180 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HCBKCGNC_00276 1.35e-46 ypmB - - S - - - Protein conserved in bacteria
HCBKCGNC_00277 2.51e-274 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HCBKCGNC_00278 6.38e-120 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
HCBKCGNC_00279 2.53e-156 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
HCBKCGNC_00280 5.67e-173 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
HCBKCGNC_00281 3.76e-143 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HCBKCGNC_00282 4.16e-133 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HCBKCGNC_00283 2.12e-142 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HCBKCGNC_00285 1.71e-90 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HCBKCGNC_00286 3.64e-63 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
HCBKCGNC_00287 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HCBKCGNC_00288 2.81e-74 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HCBKCGNC_00289 6.94e-28 - - - - - - - -
HCBKCGNC_00291 2.58e-156 - - - K - - - LysR substrate binding domain
HCBKCGNC_00292 2.77e-242 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCBKCGNC_00293 1.23e-118 - - - S - - - Acyltransferase family
HCBKCGNC_00294 3.96e-202 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HCBKCGNC_00295 6.93e-292 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HCBKCGNC_00296 6.95e-96 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HCBKCGNC_00297 1.71e-175 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HCBKCGNC_00298 1.24e-282 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HCBKCGNC_00299 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCBKCGNC_00300 4.77e-132 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCBKCGNC_00301 9.14e-41 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCBKCGNC_00302 6.07e-123 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HCBKCGNC_00303 5.17e-167 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HCBKCGNC_00304 3.35e-65 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HCBKCGNC_00305 2.14e-95 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
HCBKCGNC_00306 2.86e-24 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
HCBKCGNC_00307 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HCBKCGNC_00308 4.34e-126 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HCBKCGNC_00309 2.92e-189 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
HCBKCGNC_00310 7.81e-147 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
HCBKCGNC_00311 2.2e-187 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HCBKCGNC_00312 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HCBKCGNC_00313 1.22e-95 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
HCBKCGNC_00314 3.42e-31 yktA - - S - - - Belongs to the UPF0223 family
HCBKCGNC_00315 9.49e-22 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily
HCBKCGNC_00316 1.36e-111 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCBKCGNC_00317 1.41e-32 - - - - - - - -
HCBKCGNC_00318 1.47e-30 ykzG - - S - - - Belongs to the UPF0356 family
HCBKCGNC_00319 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCBKCGNC_00320 1.93e-315 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HCBKCGNC_00321 5.22e-251 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HCBKCGNC_00322 6.79e-246 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HCBKCGNC_00323 9.71e-274 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HCBKCGNC_00324 0.000361 - - - S - - - Tetratricopeptide repeat
HCBKCGNC_00325 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCBKCGNC_00326 2.18e-146 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HCBKCGNC_00327 2.6e-53 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HCBKCGNC_00328 1.33e-43 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HCBKCGNC_00329 2.49e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HCBKCGNC_00330 2.38e-248 - - - E ko:K03294 - ko00000 amino acid
HCBKCGNC_00331 4.4e-78 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HCBKCGNC_00332 2.25e-144 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HCBKCGNC_00333 3.22e-74 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HCBKCGNC_00334 1.99e-37 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HCBKCGNC_00335 1.32e-55 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HCBKCGNC_00336 9.04e-263 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HCBKCGNC_00337 1.51e-53 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HCBKCGNC_00338 1.12e-187 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HCBKCGNC_00339 1.65e-289 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HCBKCGNC_00340 4.17e-129 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HCBKCGNC_00341 9.72e-35 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCBKCGNC_00342 1.08e-180 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HCBKCGNC_00343 1.56e-305 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HCBKCGNC_00344 3.47e-302 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
HCBKCGNC_00345 7.35e-69 yloU - - S - - - Asp23 family, cell envelope-related function
HCBKCGNC_00346 1.33e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HCBKCGNC_00347 4.31e-73 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HCBKCGNC_00348 1.38e-145 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HCBKCGNC_00349 1.61e-237 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HCBKCGNC_00350 3.18e-115 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HCBKCGNC_00351 7.17e-192 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HCBKCGNC_00352 1.55e-177 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HCBKCGNC_00353 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HCBKCGNC_00354 1.87e-153 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HCBKCGNC_00355 8.22e-30 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HCBKCGNC_00356 8.34e-132 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HCBKCGNC_00357 5.39e-120 - - - M - - - Phosphotransferase enzyme family
HCBKCGNC_00358 9.86e-36 spxA 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
HCBKCGNC_00359 2.21e-236 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HCBKCGNC_00360 2.21e-19 - - - S - - - Protein of unknown function (DUF2969)
HCBKCGNC_00361 3.25e-36 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
HCBKCGNC_00362 2.82e-214 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
HCBKCGNC_00363 2.53e-261 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCBKCGNC_00364 8.32e-21 ywzB - - S - - - Protein of unknown function (DUF1146)
HCBKCGNC_00365 3.59e-69 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HCBKCGNC_00366 8.04e-313 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HCBKCGNC_00367 3.29e-181 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HCBKCGNC_00368 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HCBKCGNC_00369 1.62e-73 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCBKCGNC_00370 2.96e-57 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HCBKCGNC_00371 1.39e-27 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCBKCGNC_00372 2.33e-124 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HCBKCGNC_00373 2.18e-129 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HCBKCGNC_00374 1.9e-171 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HCBKCGNC_00375 7.51e-114 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HCBKCGNC_00376 4.22e-230 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HCBKCGNC_00377 1.19e-111 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HCBKCGNC_00378 1.79e-278 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
HCBKCGNC_00379 9.35e-141 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
HCBKCGNC_00380 2.05e-138 ampC - - V - - - Beta-lactamase
HCBKCGNC_00381 1.83e-41 - - - - - - - -
HCBKCGNC_00382 7.44e-153 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HCBKCGNC_00383 8.61e-258 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HCBKCGNC_00385 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HCBKCGNC_00386 5.74e-218 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HCBKCGNC_00387 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HCBKCGNC_00388 3.65e-75 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HCBKCGNC_00389 1.51e-165 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HCBKCGNC_00390 7.4e-120 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HCBKCGNC_00391 1.16e-151 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HCBKCGNC_00392 6.33e-74 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HCBKCGNC_00393 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HCBKCGNC_00394 2.85e-35 ylxQ - - J - - - ribosomal protein
HCBKCGNC_00395 3.32e-53 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
HCBKCGNC_00396 1.25e-216 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HCBKCGNC_00397 1.16e-85 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HCBKCGNC_00398 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCBKCGNC_00399 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HCBKCGNC_00400 2.52e-196 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HCBKCGNC_00401 1.58e-131 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HCBKCGNC_00402 2.86e-134 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HCBKCGNC_00403 8.26e-105 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HCBKCGNC_00404 1.02e-147 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HCBKCGNC_00405 8.28e-64 manO - - S - - - Domain of unknown function (DUF956)
HCBKCGNC_00406 4.51e-40 ogt 2.1.1.63 - L ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HCBKCGNC_00409 3.28e-312 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HCBKCGNC_00410 1.3e-59 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
HCBKCGNC_00411 1.56e-257 ynbB - - P - - - aluminum resistance
HCBKCGNC_00412 6.09e-141 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HCBKCGNC_00413 6.17e-24 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
HCBKCGNC_00414 2.92e-60 yqhL - - P - - - Rhodanese-like protein
HCBKCGNC_00415 8.22e-203 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HCBKCGNC_00416 2.47e-34 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
HCBKCGNC_00417 1.11e-90 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
HCBKCGNC_00418 2.55e-49 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HCBKCGNC_00419 7.58e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HCBKCGNC_00421 1.14e-85 yciQ - - P - - - membrane protein (DUF2207)
HCBKCGNC_00422 2.16e-58 - - - S - - - mazG nucleotide pyrophosphohydrolase
HCBKCGNC_00423 2.28e-118 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HCBKCGNC_00424 3.98e-36 yneF - - S ko:K09976 - ko00000 UPF0154 protein
HCBKCGNC_00425 7.41e-41 ynzC - - S - - - UPF0291 protein
HCBKCGNC_00426 1.83e-106 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HCBKCGNC_00427 1.05e-235 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HCBKCGNC_00428 5.91e-65 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HCBKCGNC_00429 6.31e-154 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HCBKCGNC_00430 2.19e-104 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HCBKCGNC_00431 1.44e-23 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCBKCGNC_00432 9.95e-183 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCBKCGNC_00433 1.91e-132 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HCBKCGNC_00434 1.77e-47 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HCBKCGNC_00435 1.4e-60 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
HCBKCGNC_00436 3.77e-123 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HCBKCGNC_00437 1.45e-48 - - - S - - - Protein conserved in bacteria
HCBKCGNC_00438 1.61e-147 - - - - - - - -
HCBKCGNC_00439 4.27e-143 - - - - - - - -
HCBKCGNC_00440 3.54e-172 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
HCBKCGNC_00441 1.6e-24 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HCBKCGNC_00442 1.19e-151 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCBKCGNC_00443 3.54e-99 yitS - - S - - - EDD domain protein, DegV family
HCBKCGNC_00444 7.61e-74 - - - K - - - Domain of unknown function (DUF1836)
HCBKCGNC_00445 1.29e-146 queH 1.17.99.6 - C ko:K09765 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HCBKCGNC_00446 2.58e-184 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
HCBKCGNC_00447 1.93e-215 potE2 - - E ko:K03294 - ko00000 amino acid
HCBKCGNC_00450 2.61e-16 - - - - - - - -
HCBKCGNC_00453 1.9e-48 - - - - - - - -
HCBKCGNC_00454 7.01e-56 - - - - - - - -
HCBKCGNC_00455 0.0 - 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 Putative ATP-dependent Lon protease
HCBKCGNC_00456 0.0 - - - S - - - TIGR02687 family
HCBKCGNC_00457 0.0 - - - V - - - restriction
HCBKCGNC_00458 0.0 - - - K - - - RNA-binding protein homologous to eukaryotic snRNP
HCBKCGNC_00459 8.69e-89 - - - S - - - Domain of unknown function (DUF1788)
HCBKCGNC_00460 1.17e-103 - - - S - - - Putative inner membrane protein (DUF1819)
HCBKCGNC_00461 3.85e-36 - - - K - - - Cro/C1-type HTH DNA-binding domain
HCBKCGNC_00462 3.1e-64 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
HCBKCGNC_00464 3.81e-134 - - - L - - - Belongs to the 'phage' integrase family
HCBKCGNC_00465 7.06e-27 - - - S - - - YjcQ protein
HCBKCGNC_00467 6.46e-141 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HCBKCGNC_00468 2.46e-277 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
HCBKCGNC_00469 8.21e-53 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
HCBKCGNC_00470 1.26e-272 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HCBKCGNC_00471 4.7e-239 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
HCBKCGNC_00472 1.8e-94 - - - K - - - helix_turn_helix, arabinose operon control protein
HCBKCGNC_00473 5.17e-63 - - - S - - - Membrane
HCBKCGNC_00474 3.31e-231 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
HCBKCGNC_00475 5.14e-75 yvbG - - U ko:K05595 - ko00000,ko02000 MarC family integral membrane protein
HCBKCGNC_00476 2.8e-15 - - - GKT - - - COG3711 Transcriptional antiterminator
HCBKCGNC_00477 4.23e-38 - - - O - - - Belongs to the sulfur carrier protein TusA family
HCBKCGNC_00478 1.31e-187 - - - S ko:K07112 - ko00000 Sulphur transport
HCBKCGNC_00479 8.28e-125 selD 2.7.9.3 - E ko:K01008 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000,ko03016 Synthesizes selenophosphate from selenide and ATP
HCBKCGNC_00480 3.12e-235 - - - C - - - RnfC Barrel sandwich hybrid domain
HCBKCGNC_00481 3.75e-38 - - - S - - - Iron-sulfur cluster assembly protein
HCBKCGNC_00482 1.12e-142 selA 2.9.1.1 - J ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
HCBKCGNC_00483 1.37e-137 - - - E - - - Serine hydroxymethyltransferase
HCBKCGNC_00484 4.63e-169 selB - - J ko:K03833 - ko00000,ko03012 Elongation factor SelB, winged helix
HCBKCGNC_00486 2.05e-61 yedF - - O - - - Belongs to the sulfur carrier protein TusA family
HCBKCGNC_00487 1.53e-280 - - - E - - - amino acid
HCBKCGNC_00488 5.57e-123 - - - S - - - Sulfite exporter TauE/SafE
HCBKCGNC_00489 3.01e-182 - 5.1.1.4 - E ko:K01777 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 Proline racemase
HCBKCGNC_00490 6.97e-87 - - - EJ - - - Glycine/sarcosine/betaine reductase component B subunits
HCBKCGNC_00491 2.76e-90 - - - S - - - An automated process has identified a potential problem with this gene model
HCBKCGNC_00492 2.69e-42 - - - S - - - the current gene model (or a revised gene model) may contain a premature stop
HCBKCGNC_00493 8.02e-85 prdB - - S - - - the current gene model (or a revised gene model) may contain a premature stop
HCBKCGNC_00494 6.38e-34 - - - S - - - Psort location Cytoplasmic, score
HCBKCGNC_00495 1.68e-291 prdA 1.21.4.1 - EJ ko:K10793 ko00330,map00330 ko00000,ko00001,ko01000 Glycine/sarcosine/betaine reductase component B subunits
HCBKCGNC_00497 2.75e-147 - - - P - - - Rhodanese Homology Domain
HCBKCGNC_00498 1.15e-23 - - - O - - - Belongs to the sulfur carrier protein TusA family
HCBKCGNC_00499 1.71e-80 - - - S - - - Sulphur transport
HCBKCGNC_00500 3.87e-131 - - - S ko:K07089 - ko00000 Predicted permease
HCBKCGNC_00501 3.58e-158 yvgN - - C - - - Aldo keto reductase
HCBKCGNC_00503 1.36e-80 - - - D - - - Peptidase family M23
HCBKCGNC_00504 1.31e-91 - - - M - - - transferase activity, transferring glycosyl groups
HCBKCGNC_00505 4.85e-69 - - - - - - - -
HCBKCGNC_00506 2.62e-202 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HCBKCGNC_00507 1.12e-62 - - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase, family 2
HCBKCGNC_00508 9.57e-248 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HCBKCGNC_00509 5.92e-120 - - - M - - - Core-2/I-Branching enzyme
HCBKCGNC_00510 5.92e-116 epsE2 - - M - - - Bacterial sugar transferase
HCBKCGNC_00511 1.15e-162 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HCBKCGNC_00512 5.99e-142 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HCBKCGNC_00513 3.85e-118 ywqD - - D - - - Capsular exopolysaccharide family
HCBKCGNC_00514 2.84e-98 epsB - - M - - - biosynthesis protein
HCBKCGNC_00515 4.01e-270 ugd 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 UDP binding domain
HCBKCGNC_00517 2.24e-51 - - - S - - - Acyltransferase family
HCBKCGNC_00518 4.66e-163 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HCBKCGNC_00519 1.52e-18 - - - S - - - Hexapeptide repeat of succinyl-transferase
HCBKCGNC_00520 6.97e-52 - - - M - - - Glycosyltransferase like family 2
HCBKCGNC_00523 9.03e-05 yibD - GT2 M ko:K19354 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferases involved in cell wall biogenesis
HCBKCGNC_00524 9.71e-178 - - - M - - - Glycosyl transferase family 2
HCBKCGNC_00525 9.62e-82 - - - S - - - Hexapeptide repeat of succinyl-transferase
HCBKCGNC_00526 1.17e-146 - - - G - - - Glycosyltransferase Family 4
HCBKCGNC_00527 1.73e-219 wchF - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
HCBKCGNC_00529 2.04e-112 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HCBKCGNC_00531 7.12e-147 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
HCBKCGNC_00532 3.15e-161 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HCBKCGNC_00533 2.56e-213 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HCBKCGNC_00534 2.26e-130 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HCBKCGNC_00535 1.71e-184 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HCBKCGNC_00536 1.45e-79 - - - S - - - Glycosyltransferase like family 2
HCBKCGNC_00537 1.14e-75 - - - S - - - Glycosyltransferase like family 2
HCBKCGNC_00538 7e-149 cps3J - - M - - - Domain of unknown function (DUF4422)
HCBKCGNC_00539 1.3e-47 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
HCBKCGNC_00540 2.62e-114 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
HCBKCGNC_00541 1.03e-81 - - - S - - - Haloacid dehalogenase-like hydrolase
HCBKCGNC_00542 1.04e-190 - - - EGP - - - Major Facilitator
HCBKCGNC_00544 1.34e-88 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HCBKCGNC_00545 8.26e-36 adhR - - K - - - transcriptional regulator
HCBKCGNC_00546 1.88e-114 - - - S - - - NADPH-dependent FMN reductase
HCBKCGNC_00547 1.8e-123 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HCBKCGNC_00548 3.58e-72 - - - S - - - ECF transporter, substrate-specific component
HCBKCGNC_00549 4.23e-139 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HCBKCGNC_00550 1.6e-126 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HCBKCGNC_00551 5.14e-132 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HCBKCGNC_00552 1.52e-45 - - - - - - - -
HCBKCGNC_00553 2.21e-73 - - - S - - - Protein of unknown function (DUF1129)
HCBKCGNC_00554 5.93e-242 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HCBKCGNC_00555 1.48e-31 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
HCBKCGNC_00556 2.06e-138 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HCBKCGNC_00557 4.97e-153 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
HCBKCGNC_00558 1.24e-103 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HCBKCGNC_00559 2.97e-129 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HCBKCGNC_00560 4.74e-161 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HCBKCGNC_00561 4.89e-89 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
HCBKCGNC_00562 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HCBKCGNC_00563 2.59e-194 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
HCBKCGNC_00564 5.09e-148 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HCBKCGNC_00565 5.91e-61 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HCBKCGNC_00566 1.36e-171 arcT - - E - - - Cys/Met metabolism PLP-dependent enzyme
HCBKCGNC_00567 7.69e-115 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HCBKCGNC_00568 1.9e-31 veg - - S - - - Biofilm formation stimulator VEG
HCBKCGNC_00569 1.61e-170 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HCBKCGNC_00570 5.68e-111 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HCBKCGNC_00571 3.62e-133 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
HCBKCGNC_00572 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HCBKCGNC_00573 6.48e-162 - - - - - - - -
HCBKCGNC_00574 2.66e-191 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
HCBKCGNC_00575 1.49e-54 - - - ET - - - Bacterial extracellular solute-binding proteins, family 3
HCBKCGNC_00576 2.7e-40 - - - K - - - Bacterial regulatory proteins, tetR family
HCBKCGNC_00577 5.19e-130 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HCBKCGNC_00578 1.58e-105 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
HCBKCGNC_00579 2.78e-129 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HCBKCGNC_00580 2.82e-217 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HCBKCGNC_00581 1.12e-159 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HCBKCGNC_00582 0.0 - - - L - - - DNA helicase
HCBKCGNC_00584 1.77e-155 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HCBKCGNC_00585 3.17e-94 lemA - - S ko:K03744 - ko00000 LemA family
HCBKCGNC_00586 1.2e-67 ymdB - - L - - - phosphatase homologous to the C-terminal domain of histone macroH2A1
HCBKCGNC_00587 5.29e-59 yyaT - - K ko:K02348 - ko00000 protein acetylation
HCBKCGNC_00588 1.29e-11 - - - - - - - -
HCBKCGNC_00589 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
HCBKCGNC_00590 3.61e-213 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HCBKCGNC_00591 1.24e-45 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HCBKCGNC_00592 4.44e-44 - - - K - - - Bacterial regulatory proteins, tetR family
HCBKCGNC_00593 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HCBKCGNC_00594 1.28e-276 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HCBKCGNC_00595 1.18e-149 - - - G - - - Transporter, major facilitator family protein
HCBKCGNC_00596 1.78e-26 - - - G - - - Transporter, major facilitator family protein
HCBKCGNC_00597 5.88e-113 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HCBKCGNC_00598 3.05e-190 hpk31 - - T - - - Histidine kinase
HCBKCGNC_00599 1.21e-145 vanR - - K - - - response regulator
HCBKCGNC_00600 1.11e-105 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HCBKCGNC_00601 6.31e-115 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HCBKCGNC_00602 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HCBKCGNC_00603 1.39e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HCBKCGNC_00604 2.95e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HCBKCGNC_00605 3.15e-29 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
HCBKCGNC_00606 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCBKCGNC_00607 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCBKCGNC_00608 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HCBKCGNC_00609 6.91e-73 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HCBKCGNC_00611 2.47e-151 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HCBKCGNC_00612 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HCBKCGNC_00613 2.75e-199 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HCBKCGNC_00614 5.35e-235 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HCBKCGNC_00615 1.38e-165 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HCBKCGNC_00617 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HCBKCGNC_00618 9.07e-86 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HCBKCGNC_00619 1.18e-258 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HCBKCGNC_00620 6.89e-82 - - - C - - - FMN binding
HCBKCGNC_00621 4.09e-291 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HCBKCGNC_00623 4.97e-199 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HCBKCGNC_00624 2e-77 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
HCBKCGNC_00625 5.3e-12 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
HCBKCGNC_00626 1.36e-103 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HCBKCGNC_00627 5.93e-128 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
HCBKCGNC_00628 2.6e-166 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cobalamin-independent synthase, Catalytic domain
HCBKCGNC_00629 1.14e-92 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
HCBKCGNC_00630 1.2e-248 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HCBKCGNC_00631 2.56e-203 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HCBKCGNC_00632 1.6e-70 oxyR5 - - K - - - Transcriptional regulator
HCBKCGNC_00633 3.1e-243 - - - C - - - FMN_bind
HCBKCGNC_00634 1.03e-148 pepL 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HCBKCGNC_00635 2.42e-254 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HCBKCGNC_00636 8e-176 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HCBKCGNC_00637 4.75e-102 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
HCBKCGNC_00638 1.32e-84 - - - G - - - PTS system sorbose subfamily IIB component
HCBKCGNC_00639 7.67e-139 - - - G - - - PTS system sorbose-specific iic component
HCBKCGNC_00640 6.51e-155 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
HCBKCGNC_00641 2.02e-51 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HCBKCGNC_00642 2.06e-291 treC - - G - - - Psort location Cytoplasmic, score
HCBKCGNC_00643 1.41e-142 - - - K - - - helix_turn _helix lactose operon repressor
HCBKCGNC_00644 1.93e-167 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
HCBKCGNC_00645 2.64e-98 - - - S - - - intracellular protease amidase
HCBKCGNC_00646 1.12e-28 - - - K - - - transcriptional regulator
HCBKCGNC_00647 3.55e-190 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HCBKCGNC_00648 5.2e-57 - - - S - - - Cupredoxin-like domain
HCBKCGNC_00649 4.15e-26 - - - S - - - Cupredoxin-like domain
HCBKCGNC_00650 6.48e-317 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HCBKCGNC_00651 9.04e-78 pgm3 - - G - - - phosphoglycerate mutase family
HCBKCGNC_00652 1.14e-69 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
HCBKCGNC_00653 6.95e-112 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HCBKCGNC_00654 1.85e-278 yifK - - E ko:K03293 - ko00000 Amino acid permease
HCBKCGNC_00655 6.19e-254 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HCBKCGNC_00656 1.39e-189 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCBKCGNC_00657 1.06e-216 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCBKCGNC_00658 3.5e-229 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HCBKCGNC_00659 1.99e-196 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HCBKCGNC_00660 5.22e-21 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
HCBKCGNC_00661 9.59e-265 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HCBKCGNC_00662 1.53e-143 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
HCBKCGNC_00663 2.35e-51 - - - K - - - LytTr DNA-binding domain
HCBKCGNC_00665 2.6e-191 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
HCBKCGNC_00666 4.63e-30 - - - K - - - Transcriptional regulator C-terminal region
HCBKCGNC_00667 2.53e-60 - - - S - - - Short repeat of unknown function (DUF308)
HCBKCGNC_00668 5.58e-69 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HCBKCGNC_00669 1.49e-208 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
HCBKCGNC_00670 4.78e-86 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter
HCBKCGNC_00671 1.78e-130 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
HCBKCGNC_00672 1.22e-57 ytcD - - K - - - HxlR-like helix-turn-helix
HCBKCGNC_00673 5.75e-155 ytbE - - S - - - reductase
HCBKCGNC_00674 1.11e-93 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCBKCGNC_00675 2.78e-54 - - - K - - - Acetyltransferase GNAT Family
HCBKCGNC_00676 1.37e-61 hmpT - - S - - - ECF-type riboflavin transporter, S component
HCBKCGNC_00677 1.26e-84 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
HCBKCGNC_00678 3.07e-06 sdpI - - S - - - Protein of unknown function (DUF1648)
HCBKCGNC_00679 7.86e-140 dat 2.6.1.21 - EH ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 PFAM aminotransferase, class IV
HCBKCGNC_00680 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HCBKCGNC_00681 3.54e-59 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
HCBKCGNC_00682 4.55e-68 - - - K - - - Transcriptional regulator C-terminal region
HCBKCGNC_00683 1.8e-69 jag - - S ko:K06346 - ko00000 R3H domain protein
HCBKCGNC_00684 2.21e-73 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HCBKCGNC_00685 1.42e-42 - - - S - - - Branched-chain amino acid transport protein (AzlD)
HCBKCGNC_00686 1.4e-96 azlC - - E - - - branched-chain amino acid
HCBKCGNC_00687 3.96e-76 - - - F - - - Nucleoside 2-deoxyribosyltransferase
HCBKCGNC_00688 7.04e-149 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
HCBKCGNC_00689 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HCBKCGNC_00690 1.89e-45 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
HCBKCGNC_00691 4e-241 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
HCBKCGNC_00692 1.85e-96 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
HCBKCGNC_00693 5.69e-142 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
HCBKCGNC_00695 1.23e-265 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HCBKCGNC_00696 8.21e-78 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
HCBKCGNC_00697 5.15e-145 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
HCBKCGNC_00698 2.16e-192 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
HCBKCGNC_00699 2.82e-88 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
HCBKCGNC_00700 4.88e-66 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
HCBKCGNC_00701 3.08e-135 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HCBKCGNC_00702 2.84e-220 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
HCBKCGNC_00703 2.7e-258 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
HCBKCGNC_00704 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HCBKCGNC_00705 1.44e-236 noxE - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HCBKCGNC_00706 1.66e-51 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
HCBKCGNC_00708 3.9e-134 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HCBKCGNC_00709 7.11e-129 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HCBKCGNC_00710 9.62e-122 fliY - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HCBKCGNC_00711 3.75e-49 - - - K - - - Transcriptional regulator
HCBKCGNC_00712 6.4e-138 - - - P - - - Integral membrane protein TerC family
HCBKCGNC_00713 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HCBKCGNC_00714 1.63e-85 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCBKCGNC_00715 2.44e-235 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
HCBKCGNC_00716 5.09e-56 - - - K - - - Transcriptional regulator, GntR family
HCBKCGNC_00717 1.09e-121 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HCBKCGNC_00719 4.21e-53 ybjQ - - S - - - Belongs to the UPF0145 family
HCBKCGNC_00720 2.83e-199 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HCBKCGNC_00721 1.28e-122 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HCBKCGNC_00722 2.46e-198 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HCBKCGNC_00723 3.93e-180 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCBKCGNC_00724 5e-45 - - - - - - - -
HCBKCGNC_00725 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HCBKCGNC_00726 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HCBKCGNC_00727 5.09e-83 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
HCBKCGNC_00729 8.59e-94 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
HCBKCGNC_00730 1.47e-78 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Possible lysine decarboxylase
HCBKCGNC_00731 3.75e-200 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
HCBKCGNC_00732 0.0 ydaO - - E - - - amino acid
HCBKCGNC_00733 0.0 - - - P ko:K12952 - ko00000,ko01000 COG COG0474 Cation transport ATPase
HCBKCGNC_00734 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HCBKCGNC_00735 1.7e-46 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HCBKCGNC_00736 7.13e-42 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
HCBKCGNC_00737 1.52e-126 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HCBKCGNC_00738 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
HCBKCGNC_00739 5.06e-206 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HCBKCGNC_00740 1.9e-19 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HCBKCGNC_00741 5.25e-88 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
HCBKCGNC_00742 4.01e-178 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
HCBKCGNC_00743 9.93e-104 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HCBKCGNC_00744 2.83e-120 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HCBKCGNC_00745 3.85e-52 yabA - - L - - - Involved in initiation control of chromosome replication
HCBKCGNC_00746 2.31e-105 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HCBKCGNC_00747 1.53e-83 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HCBKCGNC_00748 4.16e-39 yaaL - - S - - - Protein of unknown function (DUF2508)
HCBKCGNC_00749 6.62e-126 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HCBKCGNC_00750 3.8e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HCBKCGNC_00751 3.13e-267 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCBKCGNC_00752 1.11e-80 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HCBKCGNC_00753 3.19e-96 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HCBKCGNC_00754 1.36e-37 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
HCBKCGNC_00755 1.81e-58 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
HCBKCGNC_00756 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCBKCGNC_00757 1.1e-203 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCBKCGNC_00758 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HCBKCGNC_00759 7.33e-71 - - - - - - - -
HCBKCGNC_00760 2.18e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HCBKCGNC_00761 2.21e-97 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HCBKCGNC_00762 9.98e-150 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HCBKCGNC_00763 2.58e-88 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HCBKCGNC_00764 3.13e-109 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HCBKCGNC_00765 1.78e-15 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HCBKCGNC_00766 3.3e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HCBKCGNC_00767 2.25e-91 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
HCBKCGNC_00768 2.29e-139 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCBKCGNC_00769 3.45e-73 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HCBKCGNC_00770 1.85e-262 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HCBKCGNC_00771 7.38e-313 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HCBKCGNC_00772 1.38e-195 yacL - - S - - - domain protein
HCBKCGNC_00773 1.38e-284 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HCBKCGNC_00774 4.81e-95 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
HCBKCGNC_00775 1.17e-25 HA62_12640 - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
HCBKCGNC_00776 1.48e-280 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HCBKCGNC_00777 2.56e-45 - - - S - - - Enterocin A Immunity
HCBKCGNC_00778 5.83e-109 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HCBKCGNC_00779 4.29e-163 - - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
HCBKCGNC_00780 1.08e-147 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HCBKCGNC_00782 2.41e-56 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HCBKCGNC_00783 7.99e-316 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
HCBKCGNC_00784 3.23e-166 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HCBKCGNC_00785 3.1e-307 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCBKCGNC_00786 4.05e-114 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HCBKCGNC_00787 9.25e-124 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HCBKCGNC_00788 3.02e-115 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCBKCGNC_00790 3.06e-41 - - - - - - - -
HCBKCGNC_00791 3.03e-33 - - - S - - - Domain of unknown function (DUF4352)
HCBKCGNC_00794 1.19e-47 - - - K - - - Peptidase S24-like
HCBKCGNC_00797 1.03e-19 - - - K - - - Cro/C1-type HTH DNA-binding domain
HCBKCGNC_00800 2.06e-19 - - - K - - - Helix-turn-helix XRE-family like proteins
HCBKCGNC_00801 4.23e-52 - - - S - - - DNA binding
HCBKCGNC_00808 6.02e-58 - - - S - - - Putative HNHc nuclease
HCBKCGNC_00809 7.4e-32 - - - L - - - N-terminal phage replisome organiser (Phage_rep_org_N)
HCBKCGNC_00812 1.36e-26 - - - - - - - -
HCBKCGNC_00813 8.04e-23 - - - - - - - -
HCBKCGNC_00814 2.1e-20 - - - - - - - -
HCBKCGNC_00823 2.23e-43 - - - S - - - Phage transcriptional regulator, ArpU family
HCBKCGNC_00824 2.3e-68 - - - V - - - Abi-like protein
HCBKCGNC_00825 8.32e-65 doc - - - ko:K07341 - ko00000,ko02048 -
HCBKCGNC_00828 3.81e-29 - - - - - - - -
HCBKCGNC_00829 4.37e-112 - - - L - - - HNH nucleases
HCBKCGNC_00830 1.05e-107 - - - L - - - Phage terminase, small subunit
HCBKCGNC_00831 0.0 - - - S - - - Phage Terminase
HCBKCGNC_00833 7.45e-245 - - - S - - - Phage portal protein
HCBKCGNC_00834 1.63e-145 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
HCBKCGNC_00835 3.54e-248 - - - S - - - Phage capsid family
HCBKCGNC_00836 7.62e-30 - - - S - - - Phage gp6-like head-tail connector protein
HCBKCGNC_00837 4.81e-64 - - - S - - - Phage head-tail joining protein
HCBKCGNC_00838 1.24e-65 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HCBKCGNC_00839 5.94e-75 - - - S - - - Protein of unknown function (DUF806)
HCBKCGNC_00840 4.18e-99 - - - S - - - Phage tail tube protein
HCBKCGNC_00841 1.3e-24 - - - S - - - Phage tail assembly chaperone proteins, TAC
HCBKCGNC_00843 0.0 - - - L - - - Phage tail tape measure protein TP901
HCBKCGNC_00844 8.81e-100 - - - S - - - Phage tail protein
HCBKCGNC_00845 3.65e-151 rny - - D ko:K12088,ko:K18682 ko03018,ko05120,map03018,map05120 ko00000,ko00001,ko00002,ko01000,ko02044,ko03019 peptidase
HCBKCGNC_00847 3.45e-29 - - - S - - - Calcineurin-like phosphoesterase
HCBKCGNC_00854 1.22e-27 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
HCBKCGNC_00855 1.18e-145 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
HCBKCGNC_00856 1.79e-65 yugI - - J ko:K07570 - ko00000 general stress protein
HCBKCGNC_00857 1.63e-118 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HCBKCGNC_00858 3.79e-118 dedA - - S ko:K03975 - ko00000 SNARE associated Golgi protein
HCBKCGNC_00859 4.54e-38 - - - S - - - Protein of unknown function (DUF1461)
HCBKCGNC_00860 1.19e-145 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HCBKCGNC_00861 4.29e-77 yutD - - S - - - Protein of unknown function (DUF1027)
HCBKCGNC_00862 9.2e-73 - - - S - - - Calcineurin-like phosphoesterase
HCBKCGNC_00863 3.13e-239 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HCBKCGNC_00864 1.41e-123 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HCBKCGNC_00868 7.13e-18 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
HCBKCGNC_00869 4.34e-36 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
HCBKCGNC_00870 7.88e-122 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
HCBKCGNC_00871 5.53e-153 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
HCBKCGNC_00872 4.05e-130 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCBKCGNC_00873 4e-153 yebC - - K - - - Transcriptional regulatory protein
HCBKCGNC_00874 4.81e-54 - - - S - - - VanZ like family
HCBKCGNC_00875 1.26e-202 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HCBKCGNC_00876 9.17e-219 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HCBKCGNC_00878 6.19e-10 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HCBKCGNC_00880 3.43e-96 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCBKCGNC_00881 3.39e-47 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HCBKCGNC_00882 8.68e-83 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
HCBKCGNC_00883 1.97e-53 - - - K - - - Domain of unknown function (DUF1836)
HCBKCGNC_00884 2.71e-107 - - - S - - - membrane
HCBKCGNC_00885 1.39e-100 - - - S - - - VIT family
HCBKCGNC_00886 1.21e-188 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
HCBKCGNC_00887 6.44e-73 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HCBKCGNC_00888 5.27e-148 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCBKCGNC_00889 7.48e-147 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCBKCGNC_00890 6.71e-155 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
HCBKCGNC_00891 2.58e-150 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HCBKCGNC_00892 1.76e-124 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HCBKCGNC_00893 1.01e-53 yjbH - - Q - - - Thioredoxin
HCBKCGNC_00894 3.54e-288 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HCBKCGNC_00895 1.87e-85 coiA - - S ko:K06198 - ko00000 Competence protein
HCBKCGNC_00896 1.53e-61 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HCBKCGNC_00897 3.58e-273 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
HCBKCGNC_00909 4.53e-54 - - - L ko:K07497 - ko00000 hmm pf00665
HCBKCGNC_00910 6.46e-27 tnp - - - ko:K07498 - ko00000 -
HCBKCGNC_00911 1.32e-33 - - - L ko:K07498 - ko00000 Transposase
HCBKCGNC_00912 3.43e-45 - - - P - - - Heavy-metal-associated domain
HCBKCGNC_00913 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
HCBKCGNC_00914 1.2e-28 - - - L ko:K07483 - ko00000 PFAM transposase IS3 IS911 family protein
HCBKCGNC_00915 6.56e-52 - - - L ko:K07497 - ko00000 Integrase core domain
HCBKCGNC_00916 1.71e-43 - - - L ko:K07497 - ko00000 Integrase core domain
HCBKCGNC_00917 7.6e-168 - - - EGP - - - Major Facilitator Superfamily
HCBKCGNC_00918 1.41e-122 - - - EGP - - - Major Facilitator Superfamily
HCBKCGNC_00919 3.72e-89 - - - K - - - Transcriptional regulator, LysR family
HCBKCGNC_00920 6.08e-176 - - - G - - - Xylose isomerase-like TIM barrel
HCBKCGNC_00921 9.99e-148 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HCBKCGNC_00922 2.95e-271 - 1.3.5.1, 1.3.5.4 - C ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HCBKCGNC_00923 2.43e-174 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HCBKCGNC_00924 4.79e-89 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HCBKCGNC_00925 6.28e-181 xerS - - L ko:K04763 - ko00000,ko03036 Phage integrase family
HCBKCGNC_00929 2.67e-112 bsh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
HCBKCGNC_00930 3.03e-88 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HCBKCGNC_00931 5.82e-98 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
HCBKCGNC_00932 1.22e-72 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HCBKCGNC_00933 1.94e-67 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
HCBKCGNC_00934 6.88e-100 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HCBKCGNC_00937 1.7e-12 yhaI - - S - - - Protein of unknown function (DUF805)
HCBKCGNC_00938 9.75e-07 lanR - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HCBKCGNC_00939 1.15e-126 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HCBKCGNC_00940 3.52e-100 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HCBKCGNC_00941 6.31e-35 - - - - - - - -
HCBKCGNC_00942 3.76e-18 - - - - - - - -
HCBKCGNC_00943 6.14e-141 rssA - - S - - - Phospholipase, patatin family
HCBKCGNC_00944 5.49e-175 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HCBKCGNC_00945 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
HCBKCGNC_00946 1.93e-253 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HCBKCGNC_00947 1.6e-248 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HCBKCGNC_00948 3.5e-190 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HCBKCGNC_00949 4.48e-158 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCBKCGNC_00950 9.41e-142 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HCBKCGNC_00951 6.82e-235 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HCBKCGNC_00952 1.26e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
HCBKCGNC_00953 7.37e-175 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HCBKCGNC_00954 4.84e-72 - - - EGP - - - Transmembrane secretion effector
HCBKCGNC_00955 7.9e-257 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HCBKCGNC_00956 2.25e-216 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCBKCGNC_00957 1.76e-24 rimL 1.1.1.25 - J ko:K00014,ko:K03817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko03009 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HCBKCGNC_00958 1.94e-139 dkgB - - S - - - Aldo/keto reductase family
HCBKCGNC_00959 2.13e-32 - - - - - - - -
HCBKCGNC_00960 3.94e-99 - - - F - - - Phosphorylase superfamily
HCBKCGNC_00961 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
HCBKCGNC_00962 2.45e-79 ytkL - - S - - - Beta-lactamase superfamily domain
HCBKCGNC_00963 4.69e-122 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HCBKCGNC_00964 1.59e-156 yibE - - S - - - overlaps another CDS with the same product name
HCBKCGNC_00965 6.71e-110 - - - S - - - overlaps another CDS with the same product name
HCBKCGNC_00967 1.68e-61 spoVK - - O - - - ATPase family associated with various cellular activities (AAA)
HCBKCGNC_00969 8.25e-26 recD2_2 3.1.11.5 - L ko:K01144 - ko00000,ko01000 PIF1-like helicase
HCBKCGNC_00971 7.3e-79 - - - - - - - -
HCBKCGNC_00972 1.03e-159 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
HCBKCGNC_00973 4.87e-65 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
HCBKCGNC_00976 6.27e-158 - - - S ko:K06919 - ko00000 D5 N terminal like
HCBKCGNC_00977 4.15e-45 - - - L - - - DNA replication protein
HCBKCGNC_00986 9.67e-42 - - - K - - - Helix-turn-helix XRE-family like proteins
HCBKCGNC_00988 3.98e-147 - - - L - - - Belongs to the 'phage' integrase family
HCBKCGNC_00989 7.08e-105 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HCBKCGNC_00990 1.95e-119 yycB - - P ko:K03449 - ko00000,ko02000 Major Facilitator Superfamily
HCBKCGNC_00991 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HCBKCGNC_00992 4.56e-207 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HCBKCGNC_00993 4.95e-81 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
HCBKCGNC_00994 1.03e-110 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HCBKCGNC_00995 5.23e-104 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HCBKCGNC_00996 1.02e-10 - - - K ko:K03973 - ko00000,ko02048,ko03000 PspC domain
HCBKCGNC_00997 2.17e-35 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
HCBKCGNC_00998 1.76e-169 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HCBKCGNC_00999 2.89e-143 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HCBKCGNC_01000 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HCBKCGNC_01001 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HCBKCGNC_01002 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HCBKCGNC_01003 1.23e-107 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HCBKCGNC_01004 4.6e-101 - - - GM - - - NAD dependent epimerase dehydratase family protein
HCBKCGNC_01005 7.15e-161 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HCBKCGNC_01006 9.11e-195 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HCBKCGNC_01007 2.05e-191 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HCBKCGNC_01008 2.07e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HCBKCGNC_01010 1.59e-174 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
HCBKCGNC_01011 1.19e-231 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HCBKCGNC_01012 1.99e-264 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HCBKCGNC_01013 9.95e-165 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HCBKCGNC_01014 4.33e-298 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCBKCGNC_01015 2.86e-167 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HCBKCGNC_01016 1.95e-134 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
HCBKCGNC_01017 8.04e-212 yclK - - T - - - Histidine kinase
HCBKCGNC_01018 5.39e-189 - - - E - - - Major Facilitator Superfamily
HCBKCGNC_01019 6.32e-224 eriC - - P ko:K03281 - ko00000 chloride
HCBKCGNC_01020 1.19e-32 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HCBKCGNC_01021 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HCBKCGNC_01022 4.3e-91 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HCBKCGNC_01023 3.91e-53 - - - - - - - -
HCBKCGNC_01024 1.18e-148 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
HCBKCGNC_01025 1.52e-134 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HCBKCGNC_01026 7.01e-181 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
HCBKCGNC_01027 7.04e-73 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
HCBKCGNC_01028 2.74e-89 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HCBKCGNC_01029 2.46e-145 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HCBKCGNC_01030 3.92e-92 - - - S - - - Protein of unknown function (DUF1361)
HCBKCGNC_01031 1.95e-162 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HCBKCGNC_01032 2.27e-87 ybbR - - S - - - YbbR-like protein
HCBKCGNC_01033 1.1e-284 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HCBKCGNC_01034 1.59e-38 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
HCBKCGNC_01035 1.53e-163 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HCBKCGNC_01036 8.5e-24 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
HCBKCGNC_01037 7e-250 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCBKCGNC_01038 1.61e-207 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCBKCGNC_01039 8.29e-83 - - - J ko:K03976 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
HCBKCGNC_01040 2.88e-124 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
HCBKCGNC_01041 2.62e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HCBKCGNC_01042 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HCBKCGNC_01043 1.2e-135 ymfF - - S - - - Peptidase M16 inactive domain protein
HCBKCGNC_01044 2.81e-184 ymfH - - S - - - Peptidase M16
HCBKCGNC_01045 5.2e-116 ymfI 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HCBKCGNC_01046 7.25e-85 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
HCBKCGNC_01047 2.09e-111 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HCBKCGNC_01048 1.84e-203 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HCBKCGNC_01049 1.78e-255 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HCBKCGNC_01050 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HCBKCGNC_01051 1.41e-287 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HCBKCGNC_01052 2.19e-91 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HCBKCGNC_01053 1.45e-193 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HCBKCGNC_01054 2.88e-231 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HCBKCGNC_01055 5.96e-263 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HCBKCGNC_01056 1.06e-20 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
HCBKCGNC_01058 3.61e-79 uspA3 - - T - - - universal stress protein
HCBKCGNC_01060 2.92e-264 - - - E ko:K03294 - ko00000 Amino Acid
HCBKCGNC_01061 3.54e-150 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
HCBKCGNC_01062 2.86e-310 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
HCBKCGNC_01063 3.13e-85 lutC - - S ko:K00782 - ko00000 LUD domain
HCBKCGNC_01064 7.88e-184 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCBKCGNC_01065 3.5e-18 - - - - - - - -
HCBKCGNC_01066 1.25e-153 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
HCBKCGNC_01067 4.29e-236 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HCBKCGNC_01068 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HCBKCGNC_01069 2.44e-49 yrzL - - S - - - Belongs to the UPF0297 family
HCBKCGNC_01070 3.16e-78 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HCBKCGNC_01071 4.23e-44 yrzB - - S - - - Belongs to the UPF0473 family
HCBKCGNC_01072 3.67e-17 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HCBKCGNC_01073 3.86e-20 cvpA - - S - - - Colicin V production protein
HCBKCGNC_01074 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HCBKCGNC_01075 5.23e-54 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HCBKCGNC_01076 3.55e-79 yslB - - S - - - Protein of unknown function (DUF2507)
HCBKCGNC_01077 4.41e-94 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HCBKCGNC_01078 2.57e-53 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
HCBKCGNC_01081 2.44e-178 - 1.1.1.29 - C ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCBKCGNC_01082 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HCBKCGNC_01083 1.65e-272 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HCBKCGNC_01084 8.36e-254 oatA - - I - - - Acyltransferase
HCBKCGNC_01085 1.68e-22 - - - - - - - -
HCBKCGNC_01087 3.04e-179 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HCBKCGNC_01088 1.59e-126 yqjQ - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
HCBKCGNC_01089 1.17e-266 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HCBKCGNC_01090 4.3e-104 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HCBKCGNC_01091 0.0 - - - S - - - membrane
HCBKCGNC_01092 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HCBKCGNC_01093 3e-36 - - - S - - - Protein of unknown function (DUF3290)
HCBKCGNC_01094 5.95e-96 yviA - - S - - - Protein of unknown function (DUF421)
HCBKCGNC_01096 5.94e-158 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HCBKCGNC_01097 5.17e-253 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HCBKCGNC_01098 1.19e-69 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HCBKCGNC_01099 6.08e-95 uspA - - T - - - universal stress protein
HCBKCGNC_01101 7.05e-242 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HCBKCGNC_01102 4.14e-31 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
HCBKCGNC_01103 5.9e-130 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HCBKCGNC_01104 6.33e-73 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HCBKCGNC_01105 2.45e-225 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HCBKCGNC_01106 2.81e-204 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HCBKCGNC_01107 1.44e-248 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HCBKCGNC_01108 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HCBKCGNC_01109 8.51e-170 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HCBKCGNC_01110 3.22e-102 radC - - L ko:K03630 - ko00000 DNA repair protein
HCBKCGNC_01111 1.96e-29 - - - K ko:K03704 - ko00000,ko03000 Cold shock
HCBKCGNC_01112 2.35e-207 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
HCBKCGNC_01113 1.64e-121 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HCBKCGNC_01114 1.33e-70 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
HCBKCGNC_01115 3.56e-98 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HCBKCGNC_01116 7.95e-163 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
HCBKCGNC_01117 3.02e-122 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HCBKCGNC_01118 2.01e-115 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HCBKCGNC_01119 3.24e-138 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HCBKCGNC_01120 4.54e-124 ybcH - - D ko:K06889 - ko00000 Alpha beta
HCBKCGNC_01121 1.16e-05 - - - S - - - Protein of unknown function (DUF4044)
HCBKCGNC_01122 7.7e-196 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
HCBKCGNC_01124 5.35e-82 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HCBKCGNC_01125 3.67e-180 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HCBKCGNC_01126 1.05e-13 ftsL - - D - - - Essential cell division protein
HCBKCGNC_01127 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HCBKCGNC_01128 3.64e-172 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HCBKCGNC_01129 2.97e-233 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HCBKCGNC_01130 1.05e-195 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HCBKCGNC_01131 6.44e-76 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HCBKCGNC_01132 6.07e-240 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HCBKCGNC_01133 1.29e-228 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HCBKCGNC_01134 8.14e-43 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HCBKCGNC_01135 8.19e-27 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
HCBKCGNC_01136 5.69e-104 ylmH - - S - - - S4 domain protein
HCBKCGNC_01137 1.61e-91 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
HCBKCGNC_01138 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HCBKCGNC_01139 1.5e-29 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCBKCGNC_01140 1.62e-176 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
HCBKCGNC_01141 8.89e-188 - - - E - - - glutamate:sodium symporter activity
HCBKCGNC_01142 3.01e-183 - - - Q - - - Imidazolonepropionase and related amidohydrolases
HCBKCGNC_01143 1.66e-57 cps3F - - - - - - -
HCBKCGNC_01145 6.41e-97 - - - S - - - Membrane
HCBKCGNC_01146 0.0 - - - E - - - Amino acid permease
HCBKCGNC_01147 1.51e-93 cadA - - P - - - P-type ATPase
HCBKCGNC_01148 1.95e-169 cadA - - P - - - P-type ATPase
HCBKCGNC_01149 2.47e-146 degV - - S - - - EDD domain protein, DegV family
HCBKCGNC_01150 2.05e-189 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
HCBKCGNC_01151 1.18e-69 - - - F - - - glutamine amidotransferase
HCBKCGNC_01152 1.86e-35 yuxO - - Q - - - Thioesterase superfamily
HCBKCGNC_01153 6.07e-186 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HCBKCGNC_01154 1.7e-175 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HCBKCGNC_01155 1.18e-103 - - - S - - - L,D-transpeptidase catalytic domain
HCBKCGNC_01156 1.44e-208 - - - EGP ko:K18934 - ko00000,ko02000 Major Facilitator Superfamily
HCBKCGNC_01157 5.68e-21 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HCBKCGNC_01158 2.98e-284 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HCBKCGNC_01159 9.74e-159 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HCBKCGNC_01160 1.39e-42 - - - S - - - Protein of unknown function (DUF1634)
HCBKCGNC_01161 3.16e-153 - - - S ko:K07090 - ko00000 membrane transporter protein
HCBKCGNC_01162 1.02e-105 lysR5 - - K - - - LysR substrate binding domain
HCBKCGNC_01163 3.04e-71 lssY 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
HCBKCGNC_01164 2.9e-14 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HCBKCGNC_01165 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HCBKCGNC_01166 3.19e-86 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
HCBKCGNC_01167 2.64e-308 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
HCBKCGNC_01168 1.6e-262 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HCBKCGNC_01169 8.47e-223 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
HCBKCGNC_01170 2.1e-161 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HCBKCGNC_01171 2.54e-214 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HCBKCGNC_01172 4.64e-113 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HCBKCGNC_01173 1.87e-65 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HCBKCGNC_01174 4.03e-08 XK27_08315 - - M - - - Sulfatase
HCBKCGNC_01175 2.16e-209 XK27_08315 - - M - - - Sulfatase
HCBKCGNC_01177 1.18e-212 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HCBKCGNC_01178 8.27e-316 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HCBKCGNC_01179 1.68e-108 treR - - K ko:K03486 - ko00000,ko03000 UTRA
HCBKCGNC_01180 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HCBKCGNC_01181 1.14e-81 pgm1 - - G - - - phosphoglycerate mutase
HCBKCGNC_01182 5.94e-107 pncA - - Q - - - isochorismatase
HCBKCGNC_01183 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HCBKCGNC_01184 7.07e-66 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HCBKCGNC_01185 8.92e-134 gntR - - K - - - UbiC transcription regulator-associated domain protein
HCBKCGNC_01186 6.68e-219 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HCBKCGNC_01187 6.93e-55 hxlR - - K - - - Transcriptional regulator, HxlR family
HCBKCGNC_01188 2.21e-208 - - - C - - - Luciferase-like monooxygenase
HCBKCGNC_01189 8.65e-62 - - - V - - - Type I restriction modification DNA specificity domain
HCBKCGNC_01190 1.94e-47 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
HCBKCGNC_01191 5.11e-200 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 cog cog0286
HCBKCGNC_01192 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
HCBKCGNC_01193 3.6e-27 - - - K - - - Cro/C1-type HTH DNA-binding domain
HCBKCGNC_01194 5.08e-89 - - - L - - - AAA domain
HCBKCGNC_01195 3.16e-09 - - - - - - - -
HCBKCGNC_01196 4.38e-26 - - - - - - - -
HCBKCGNC_01197 1e-96 rha - - K - - - phage regulatory protein, rha family
HCBKCGNC_01199 4.47e-154 - - - L ko:K07448 - ko00000,ko02048 Mrr N-terminal domain
HCBKCGNC_01200 3.02e-265 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCBKCGNC_01201 5.92e-182 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
HCBKCGNC_01202 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCBKCGNC_01203 5.93e-294 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HCBKCGNC_01204 1.34e-50 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCBKCGNC_01205 1.39e-204 camS - - S - - - sex pheromone
HCBKCGNC_01206 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HCBKCGNC_01207 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HCBKCGNC_01208 1.64e-182 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HCBKCGNC_01210 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HCBKCGNC_01211 4.6e-205 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HCBKCGNC_01212 1.5e-118 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HCBKCGNC_01213 8.69e-86 - - - S - - - NADPH-dependent FMN reductase
HCBKCGNC_01214 3.39e-195 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
HCBKCGNC_01215 2.11e-67 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
HCBKCGNC_01216 8.65e-185 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
HCBKCGNC_01217 3e-36 - - - S - - - Psort location CytoplasmicMembrane, score
HCBKCGNC_01218 4.55e-20 - - - - - - - -
HCBKCGNC_01219 2.69e-53 - - - S - - - Bacterial membrane protein, YfhO
HCBKCGNC_01220 4.72e-09 - - - S - - - Psort location CytoplasmicMembrane, score
HCBKCGNC_01221 1.06e-120 - - - S - - - Bacterial membrane protein, YfhO
HCBKCGNC_01222 4.93e-148 - - - S - - - Bacterial membrane protein YfhO
HCBKCGNC_01223 1.84e-187 XK27_08315 - - M - - - Sulfatase
HCBKCGNC_01225 5.57e-80 - - - V - - - HNH endonuclease
HCBKCGNC_01226 8.38e-169 - - - F - - - NUDIX domain
HCBKCGNC_01227 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCBKCGNC_01228 2.13e-134 pncA - - Q - - - Isochorismatase family
HCBKCGNC_01229 5.74e-129 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HCBKCGNC_01230 2.4e-312 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HCBKCGNC_01231 1.56e-229 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HCBKCGNC_01232 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HCBKCGNC_01233 2.06e-192 - - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HCBKCGNC_01234 2.42e-200 - - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HCBKCGNC_01235 3.07e-170 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HCBKCGNC_01236 3.25e-122 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
HCBKCGNC_01237 3.5e-214 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HCBKCGNC_01238 6.3e-271 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HCBKCGNC_01240 7.37e-78 - - - T - - - Universal stress protein family
HCBKCGNC_01241 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
HCBKCGNC_01242 2.65e-35 - - - - - - - -
HCBKCGNC_01243 7.58e-252 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HCBKCGNC_01244 2.14e-141 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HCBKCGNC_01245 1.46e-106 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HCBKCGNC_01246 1.25e-186 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
HCBKCGNC_01247 1.62e-186 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
HCBKCGNC_01248 3.13e-273 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HCBKCGNC_01249 4.34e-93 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HCBKCGNC_01269 5.21e-226 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HCBKCGNC_01270 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HCBKCGNC_01271 4.35e-247 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HCBKCGNC_01272 9.88e-244 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HCBKCGNC_01273 1.01e-77 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HCBKCGNC_01274 3.13e-104 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HCBKCGNC_01275 2.17e-242 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
HCBKCGNC_01276 5.57e-225 - - - S - - - Protein of unknown function DUF262
HCBKCGNC_01277 6.2e-38 tetA - - EGP ko:K08151,ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko01504,ko02000 Major facilitator Superfamily
HCBKCGNC_01278 5.91e-104 tetA - - EGP ko:K08151,ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko01504,ko02000 Major facilitator Superfamily
HCBKCGNC_01279 1.24e-43 - - - S - - - MazG nucleotide pyrophosphohydrolase domain
HCBKCGNC_01280 1.26e-268 potE - - E - - - Amino Acid
HCBKCGNC_01281 2.45e-241 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HCBKCGNC_01282 3.91e-143 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HCBKCGNC_01283 1.12e-55 - - - E - - - GDSL-like Lipase/Acylhydrolase
HCBKCGNC_01284 2.25e-170 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HCBKCGNC_01285 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HCBKCGNC_01286 2.63e-95 - - - - - - - -
HCBKCGNC_01287 2.32e-28 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HCBKCGNC_01288 2.86e-145 - - - M - - - Glycosyl transferase family 2
HCBKCGNC_01289 1.62e-30 gtcA - - S - - - Teichoic acid glycosylation protein
HCBKCGNC_01290 8.3e-160 - - - K ko:K21562 - ko00000,ko03000 helix_turn_helix, cAMP Regulatory protein
HCBKCGNC_01291 8.45e-120 - - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
HCBKCGNC_01292 2.85e-197 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HCBKCGNC_01293 9.94e-77 - - - L ko:K07491 - ko00000 Transposase IS200 like
HCBKCGNC_01294 1.22e-66 - - - C - - - Oxidoreductase NAD-binding domain
HCBKCGNC_01295 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HCBKCGNC_01296 1.73e-49 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HCBKCGNC_01298 1.83e-10 - - - K ko:K03826 - ko00000,ko01000 Acetyltransferase, GNAT family
HCBKCGNC_01299 1.23e-21 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HCBKCGNC_01300 2.69e-07 - - - K ko:K03826 - ko00000,ko01000 Psort location Cytoplasmic, score 8.87
HCBKCGNC_01301 8.46e-65 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
HCBKCGNC_01302 1.74e-74 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
HCBKCGNC_01303 6.36e-190 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
HCBKCGNC_01304 4.18e-46 - - - - - - - -
HCBKCGNC_01305 2.03e-242 repA - - S - - - Replication initiator protein A
HCBKCGNC_01306 5.03e-35 - - - - - - - -
HCBKCGNC_01307 2.49e-178 - - - S - - - Fic/DOC family
HCBKCGNC_01308 2.83e-58 - - - L - - - Addiction module antitoxin, RelB DinJ family
HCBKCGNC_01309 3.96e-37 - - - - - - - -
HCBKCGNC_01310 1.58e-38 - - - S - - - protein conserved in bacteria
HCBKCGNC_01311 2.13e-93 - - - S - - - protein conserved in bacteria
HCBKCGNC_01312 2.09e-55 - - - - - - - -
HCBKCGNC_01313 1.29e-32 - - - - - - - -
HCBKCGNC_01314 6.59e-221 - - - L - - - MobA MobL family protein
HCBKCGNC_01315 5.91e-211 - - - D - - - This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HCBKCGNC_01318 0.000248 - - - S - - - zinc-ribbon domain
HCBKCGNC_01320 7.9e-135 yhgE - - V ko:K01421 - ko00000 domain protein
HCBKCGNC_01321 6.22e-164 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HCBKCGNC_01322 1.28e-24 - - - - - - - -
HCBKCGNC_01323 1.78e-132 - - - E - - - AzlC protein
HCBKCGNC_01324 2.61e-52 - - - S - - - branched-chain amino acid
HCBKCGNC_01325 5.6e-80 - - - I - - - alpha/beta hydrolase fold
HCBKCGNC_01326 4.48e-24 - - - - - - - -
HCBKCGNC_01327 9.17e-75 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatase
HCBKCGNC_01328 2.39e-27 - - - - - - - -
HCBKCGNC_01329 5.83e-117 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HCBKCGNC_01330 3.57e-115 mntR - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
HCBKCGNC_01331 1.37e-37 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HCBKCGNC_01332 1.11e-102 - - - S - - - Putative threonine/serine exporter
HCBKCGNC_01333 3.42e-65 - - - S - - - Threonine/Serine exporter, ThrE
HCBKCGNC_01334 3.06e-157 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HCBKCGNC_01335 2.09e-110 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HCBKCGNC_01336 7.86e-46 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HCBKCGNC_01337 3.11e-28 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCBKCGNC_01338 1.18e-28 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCBKCGNC_01339 5.34e-83 - - - S - - - Uncharacterised protein, DegV family COG1307
HCBKCGNC_01341 1.09e-68 ccl - - S - - - QueT transporter
HCBKCGNC_01342 8.54e-45 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
HCBKCGNC_01343 9.04e-131 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HCBKCGNC_01344 4.34e-138 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
HCBKCGNC_01345 5.23e-219 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HCBKCGNC_01346 5.27e-122 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HCBKCGNC_01347 5.52e-111 - - - S - - - Alpha beta hydrolase
HCBKCGNC_01348 6.55e-58 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCBKCGNC_01349 2.8e-174 - - - V - - - MatE
HCBKCGNC_01350 6.88e-200 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HCBKCGNC_01351 1.28e-90 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HCBKCGNC_01352 1.13e-125 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HCBKCGNC_01353 1.13e-162 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HCBKCGNC_01354 9.47e-96 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HCBKCGNC_01355 1.57e-32 - - - - - - - -
HCBKCGNC_01356 7.94e-231 yhdP - - S - - - Transporter associated domain
HCBKCGNC_01357 1.77e-101 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HCBKCGNC_01358 0.0 - - - L - - - Helicase C-terminal domain protein
HCBKCGNC_01359 5.89e-316 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCBKCGNC_01360 1.24e-268 yhdG - - E ko:K03294 - ko00000 Amino Acid
HCBKCGNC_01361 2.87e-68 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HCBKCGNC_01362 2.09e-16 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
HCBKCGNC_01363 9.05e-123 - - - - - - - -
HCBKCGNC_01364 1.32e-17 - - - - - - - -
HCBKCGNC_01365 7.01e-132 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HCBKCGNC_01366 2.79e-125 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HCBKCGNC_01367 4.89e-111 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HCBKCGNC_01368 1.88e-104 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HCBKCGNC_01369 1e-240 steT - - E ko:K03294 - ko00000 amino acid
HCBKCGNC_01370 2.79e-14 - - - K - - - Acetyltransferase (GNAT) domain
HCBKCGNC_01371 5.86e-188 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HCBKCGNC_01372 1.15e-68 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HCBKCGNC_01373 6.12e-100 - - - K - - - rpiR family
HCBKCGNC_01374 7.36e-219 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HCBKCGNC_01375 3.24e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HCBKCGNC_01376 2.82e-140 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HCBKCGNC_01377 1.88e-129 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HCBKCGNC_01378 1.34e-52 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HCBKCGNC_01379 9.24e-183 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HCBKCGNC_01380 5.93e-60 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HCBKCGNC_01381 9.15e-72 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HCBKCGNC_01382 1.62e-149 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HCBKCGNC_01383 8.95e-95 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HCBKCGNC_01384 2.63e-32 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HCBKCGNC_01385 5.05e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HCBKCGNC_01386 4.95e-77 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HCBKCGNC_01387 3.84e-62 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HCBKCGNC_01388 1.61e-119 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HCBKCGNC_01389 4.1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCBKCGNC_01390 5.17e-86 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HCBKCGNC_01391 4.99e-113 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HCBKCGNC_01392 2.4e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HCBKCGNC_01393 2.08e-106 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HCBKCGNC_01394 1.65e-31 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HCBKCGNC_01395 1.13e-88 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HCBKCGNC_01396 1.05e-266 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HCBKCGNC_01397 8.94e-143 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HCBKCGNC_01398 7.16e-47 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HCBKCGNC_01399 1.72e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HCBKCGNC_01400 7.34e-74 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HCBKCGNC_01401 1.24e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HCBKCGNC_01402 1.93e-198 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCBKCGNC_01403 4.47e-71 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HCBKCGNC_01404 2.27e-127 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCBKCGNC_01405 8.76e-140 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCBKCGNC_01406 3.1e-138 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCBKCGNC_01407 6.22e-160 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HCBKCGNC_01408 1.04e-99 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HCBKCGNC_01409 2.29e-79 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HCBKCGNC_01411 1.98e-307 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
HCBKCGNC_01412 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HCBKCGNC_01413 9.44e-113 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HCBKCGNC_01414 9.3e-140 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HCBKCGNC_01415 8.1e-44 - - - K - - - transcriptional regulator (TetR family)
HCBKCGNC_01416 6.4e-111 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HCBKCGNC_01417 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HCBKCGNC_01418 1.92e-60 - - - M - - - LysM domain protein
HCBKCGNC_01419 1.25e-143 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HCBKCGNC_01420 6.85e-130 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
HCBKCGNC_01421 8.18e-73 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
HCBKCGNC_01422 1.43e-68 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HCBKCGNC_01423 4.09e-261 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HCBKCGNC_01424 4.44e-180 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCBKCGNC_01425 2.2e-110 - - - S - - - (CBS) domain
HCBKCGNC_01426 8.16e-202 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HCBKCGNC_01427 3.56e-96 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HCBKCGNC_01428 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HCBKCGNC_01429 1.32e-172 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HCBKCGNC_01430 1.1e-42 yabO - - J - - - S4 domain protein
HCBKCGNC_01431 1.49e-28 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HCBKCGNC_01432 1.23e-62 yabR - - J ko:K07571 - ko00000 RNA binding
HCBKCGNC_01433 9.26e-119 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HCBKCGNC_01434 2.49e-100 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HCBKCGNC_01435 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HCBKCGNC_01436 4.39e-165 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HCBKCGNC_01437 2.4e-214 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCBKCGNC_01438 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HCBKCGNC_01439 1e-53 - - - S - - - virion core protein, lumpy skin disease virus
HCBKCGNC_01440 8.68e-159 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HCBKCGNC_01441 3.84e-218 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HCBKCGNC_01442 2.26e-148 ydbI - - K - - - AI-2E family transporter
HCBKCGNC_01443 8.37e-76 - - - EG - - - EamA-like transporter family
HCBKCGNC_01444 4.55e-98 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
HCBKCGNC_01445 3.96e-147 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HCBKCGNC_01446 2.78e-85 - 1.5.1.38 - S ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
HCBKCGNC_01447 0.0 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
HCBKCGNC_01448 2.44e-104 - - - - - - - -
HCBKCGNC_01449 2.57e-60 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HCBKCGNC_01450 2.2e-202 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HCBKCGNC_01451 2.24e-15 - - - S - - - Protein of unknown function (DUF3021)
HCBKCGNC_01452 3.13e-35 - - - K ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
HCBKCGNC_01453 4.18e-75 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
HCBKCGNC_01454 4.86e-94 cylA - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
HCBKCGNC_01456 6.8e-140 - - - K - - - Bacterial regulatory proteins, tetR family
HCBKCGNC_01457 0.0 - - - EGP - - - Major Facilitator
HCBKCGNC_01458 3.17e-51 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
HCBKCGNC_01459 3.97e-136 - - - - - - - -
HCBKCGNC_01460 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HCBKCGNC_01461 8.17e-123 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HCBKCGNC_01462 3.23e-115 sip - - L - - - Belongs to the 'phage' integrase family
HCBKCGNC_01463 2.39e-42 - - - S - - - ParE toxin of type II toxin-antitoxin system, parDE
HCBKCGNC_01464 1.13e-30 - - - - - - - -
HCBKCGNC_01466 5.33e-18 - - - S - - - Domain of unknown function (DUF4393)
HCBKCGNC_01467 4.29e-260 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HCBKCGNC_01468 4.62e-116 - - - L ko:K07484 - ko00000 Transposase IS66 family
HCBKCGNC_01469 1.72e-38 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
HCBKCGNC_01470 6.57e-186 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HCBKCGNC_01471 1.1e-270 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HCBKCGNC_01472 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HCBKCGNC_01473 7.87e-229 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HCBKCGNC_01474 3.4e-144 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
HCBKCGNC_01475 1.08e-74 - - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
HCBKCGNC_01476 7.12e-68 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
HCBKCGNC_01477 4.49e-57 - - - K - - - helix_turn_helix isocitrate lyase regulation
HCBKCGNC_01478 3.37e-151 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCBKCGNC_01479 1.91e-130 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HCBKCGNC_01480 5.71e-28 - - - - - - - -
HCBKCGNC_01481 1.78e-111 - - - S - - - Predicted membrane protein (DUF2207)
HCBKCGNC_01482 3.82e-71 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HCBKCGNC_01483 1.83e-230 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
HCBKCGNC_01484 1.9e-116 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HCBKCGNC_01485 3.96e-92 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
HCBKCGNC_01486 2.35e-76 yceE - - S - - - haloacid dehalogenase-like hydrolase
HCBKCGNC_01487 7.18e-51 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HCBKCGNC_01488 1.12e-41 - - - S - - - Domain of unknown function (DUF4811)
HCBKCGNC_01489 1.41e-246 ycnB - - U - - - Belongs to the major facilitator superfamily
HCBKCGNC_01490 2.49e-43 - - - K - - - MerR HTH family regulatory protein
HCBKCGNC_01491 1.29e-51 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCBKCGNC_01492 1.22e-89 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HCBKCGNC_01493 1.19e-147 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HCBKCGNC_01494 1.46e-101 yfiK - - KT ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCBKCGNC_01495 3.34e-122 baeS - - T - - - Histidine kinase
HCBKCGNC_01496 6.18e-101 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 sugar-binding domain protein
HCBKCGNC_01497 3.19e-192 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HCBKCGNC_01498 1.69e-153 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
HCBKCGNC_01499 1.4e-188 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
HCBKCGNC_01500 1.61e-67 - - - S - - - Domain of unknown function (DUF956)
HCBKCGNC_01501 5.58e-93 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
HCBKCGNC_01502 2.89e-164 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HCBKCGNC_01503 8.6e-207 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCBKCGNC_01504 3.33e-97 ung2 - - L - - - Uracil-DNA glycosylase
HCBKCGNC_01505 8.95e-44 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HCBKCGNC_01506 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HCBKCGNC_01507 4.45e-136 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HCBKCGNC_01508 7.44e-51 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HCBKCGNC_01509 3e-38 - - - S - - - CRISPR-associated protein (Cas_Csn2)
HCBKCGNC_01510 1.77e-50 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
HCBKCGNC_01511 2.01e-27 - - - S - - - Protein of unknown function (DUF1700)
HCBKCGNC_01512 5.5e-08 - - - S - - - Putative adhesin
HCBKCGNC_01513 8.46e-23 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
HCBKCGNC_01516 2.91e-296 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HCBKCGNC_01517 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
HCBKCGNC_01518 2.31e-130 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HCBKCGNC_01519 2.11e-210 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HCBKCGNC_01520 3.85e-153 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HCBKCGNC_01521 3.11e-133 potC - - U ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HCBKCGNC_01522 1.19e-201 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HCBKCGNC_01523 7.9e-169 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HCBKCGNC_01524 9.74e-147 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HCBKCGNC_01525 5.74e-138 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HCBKCGNC_01526 3.36e-85 yciB - - M - - - ErfK YbiS YcfS YnhG
HCBKCGNC_01527 2.68e-69 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCBKCGNC_01528 2.49e-285 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HCBKCGNC_01529 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HCBKCGNC_01530 2.22e-131 pgm3 - - G - - - phosphoglycerate mutase
HCBKCGNC_01531 2.05e-70 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HCBKCGNC_01532 6.33e-62 - - - C - - - Flavodoxin
HCBKCGNC_01533 5.24e-79 yphH - - S - - - Cupin domain
HCBKCGNC_01534 1.78e-60 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
HCBKCGNC_01535 8.36e-177 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HCBKCGNC_01536 4.23e-135 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HCBKCGNC_01537 1.32e-188 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCBKCGNC_01538 2.24e-113 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HCBKCGNC_01539 1.85e-167 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HCBKCGNC_01540 2.84e-107 - - - C - - - nitroreductase
HCBKCGNC_01541 5.05e-105 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
HCBKCGNC_01542 1.16e-136 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
HCBKCGNC_01543 1.5e-214 npr 1.11.1.1 - S ko:K05910 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HCBKCGNC_01544 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
HCBKCGNC_01546 1.78e-191 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCBKCGNC_01547 1.02e-73 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HCBKCGNC_01548 3.63e-163 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HCBKCGNC_01549 5.64e-68 - - - S - - - Protein of unknown function (DUF4256)
HCBKCGNC_01552 6.07e-223 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
HCBKCGNC_01553 7.47e-213 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
HCBKCGNC_01554 2.72e-230 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HCBKCGNC_01555 1.77e-290 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
HCBKCGNC_01556 2.72e-186 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HCBKCGNC_01557 2.36e-72 - - - S - - - Protein of unknown function (DUF975)
HCBKCGNC_01558 4.91e-79 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HCBKCGNC_01559 1.01e-16 - - - - - - - -
HCBKCGNC_01560 3.81e-37 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
HCBKCGNC_01561 2.79e-281 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
HCBKCGNC_01562 1.39e-111 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
HCBKCGNC_01563 4.7e-192 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HCBKCGNC_01564 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
HCBKCGNC_01565 1.94e-40 - - - L - - - MULE transposase domain
HCBKCGNC_01566 1.77e-63 - - - S - - - VIT family
HCBKCGNC_01567 2.63e-303 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
HCBKCGNC_01568 1.15e-53 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
HCBKCGNC_01569 2.09e-184 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HCBKCGNC_01570 7.04e-178 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
HCBKCGNC_01571 2.59e-148 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
HCBKCGNC_01572 2.22e-281 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HCBKCGNC_01574 3.32e-26 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
HCBKCGNC_01575 3.04e-36 - - - K - - - Helix-turn-helix XRE-family like proteins
HCBKCGNC_01577 7.58e-43 - - - S - - - ABC-2 family transporter protein
HCBKCGNC_01578 1.06e-92 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HCBKCGNC_01579 5.88e-130 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
HCBKCGNC_01580 6.55e-113 spaR - - KT ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
HCBKCGNC_01581 2.66e-91 spaC1 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C-like protein
HCBKCGNC_01582 1.5e-227 nisT - - V ko:K06147,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ATPases associated with a variety of cellular activities
HCBKCGNC_01583 7.33e-256 bsaB - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
HCBKCGNC_01585 3.83e-173 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HCBKCGNC_01586 3.14e-147 ddh 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCBKCGNC_01587 1.26e-79 mipB 2.2.1.2 - H ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
HCBKCGNC_01588 2.21e-47 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
HCBKCGNC_01589 1.05e-172 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
HCBKCGNC_01590 1.93e-106 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
HCBKCGNC_01591 7.01e-57 srlM1 - - K - - - Glucitol operon activator protein (GutM)
HCBKCGNC_01592 7.16e-94 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
HCBKCGNC_01593 3.37e-141 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
HCBKCGNC_01594 6.35e-206 ytbD - - EGP ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
HCBKCGNC_01595 6.42e-125 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
HCBKCGNC_01596 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HCBKCGNC_01597 1.86e-189 - - - M - - - YSIRK type signal peptide
HCBKCGNC_01598 2.17e-08 - - - M - - - domain protein
HCBKCGNC_01599 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 phosphatase activity
HCBKCGNC_01600 8.56e-90 - - - L - - - Phage integrase, N-terminal SAM-like domain
HCBKCGNC_01603 2.68e-71 - - - S - - - Haloacid dehalogenase-like hydrolase
HCBKCGNC_01604 6.32e-24 - - - S - - - Haloacid dehalogenase-like hydrolase
HCBKCGNC_01605 4.81e-19 - - - - - - - -
HCBKCGNC_01607 3.3e-236 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HCBKCGNC_01608 2.66e-102 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
HCBKCGNC_01609 2.27e-86 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
HCBKCGNC_01610 5.79e-54 yitW - - S - - - Iron-sulfur cluster assembly protein
HCBKCGNC_01611 5.41e-144 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HCBKCGNC_01612 7.41e-81 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HCBKCGNC_01613 1.02e-259 - - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HCBKCGNC_01614 1.63e-193 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HCBKCGNC_01615 1.51e-81 - - - G - - - Xylose isomerase domain protein TIM barrel
HCBKCGNC_01616 3.08e-70 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
HCBKCGNC_01617 2.9e-114 nanK - - GK - - - ROK family
HCBKCGNC_01618 4.39e-162 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HCBKCGNC_01619 5.09e-118 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HCBKCGNC_01620 2.33e-95 - - - K - - - Helix-turn-helix domain, rpiR family
HCBKCGNC_01621 3.9e-38 yphA - - GM - - - NAD dependent epimerase/dehydratase family
HCBKCGNC_01622 4.36e-271 potE - - E - - - Amino Acid
HCBKCGNC_01623 1.16e-08 - - - - - - - -
HCBKCGNC_01624 5.44e-43 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCBKCGNC_01625 5.45e-287 fusA1 - - J - - - elongation factor G
HCBKCGNC_01626 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HCBKCGNC_01627 1.38e-113 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HCBKCGNC_01628 8.88e-216 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HCBKCGNC_01629 8.33e-151 - 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Alcohol dehydrogenase GroES-like domain
HCBKCGNC_01630 1.46e-233 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HCBKCGNC_01631 1.36e-47 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HCBKCGNC_01632 2.62e-52 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCBKCGNC_01633 9.75e-78 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
HCBKCGNC_01634 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HCBKCGNC_01635 1.82e-100 - - - S - - - Fic/DOC family
HCBKCGNC_01636 4.77e-162 - - - L - - - PLD-like domain
HCBKCGNC_01637 1.56e-46 - - - L - - - PLD-like domain
HCBKCGNC_01640 3.24e-142 - - - L - - - Initiator Replication protein
HCBKCGNC_01641 3.46e-46 - - - S - - - Replication initiator protein A (RepA) N-terminus
HCBKCGNC_01642 1.02e-156 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HCBKCGNC_01643 9.94e-44 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HCBKCGNC_01644 1.55e-110 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 .Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome down-regulated in Spo0A mutant
HCBKCGNC_01645 3.71e-21 bglG - - K ko:K03488 - ko00000,ko03000 antiterminator
HCBKCGNC_01646 3.22e-161 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
HCBKCGNC_01648 3.85e-48 - - - - - - - -
HCBKCGNC_01649 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
HCBKCGNC_01650 2.91e-53 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
HCBKCGNC_01651 2.78e-23 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HCBKCGNC_01653 3.58e-137 XK27_09655 - - S - - - Virulence protein RhuM family
HCBKCGNC_01654 7.12e-77 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain protein
HCBKCGNC_01655 1.08e-156 - - - S - - - Bacteriophage abortive infection AbiH
HCBKCGNC_01658 3.09e-205 spoVK - - O - - - ATPase family associated with various cellular activities (AAA)
HCBKCGNC_01659 4.9e-67 - - - K - - - Cro/C1-type HTH DNA-binding domain
HCBKCGNC_01661 4.21e-82 - - - S - - - Acetyltransferase (GNAT) domain
HCBKCGNC_01662 8.83e-93 ywlG - - S - - - Belongs to the UPF0340 family
HCBKCGNC_01663 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
HCBKCGNC_01664 2.46e-121 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HCBKCGNC_01665 6e-76 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HCBKCGNC_01666 2.02e-221 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
HCBKCGNC_01667 4.82e-20 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
HCBKCGNC_01668 7.52e-302 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HCBKCGNC_01669 4.81e-250 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HCBKCGNC_01670 3.63e-267 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HCBKCGNC_01671 7.1e-07 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HCBKCGNC_01672 1.32e-204 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCBKCGNC_01673 1.28e-76 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
HCBKCGNC_01674 1.7e-129 ypuA - - S - - - Protein of unknown function (DUF1002)
HCBKCGNC_01676 3.1e-130 - - - M - - - Rib/alpha-like repeat
HCBKCGNC_01677 3e-147 - - - M - - - Rib/alpha-like repeat
HCBKCGNC_01678 1.76e-58 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
HCBKCGNC_01679 2.3e-78 usp2 - - T - - - Belongs to the universal stress protein A family
HCBKCGNC_01680 3.34e-52 - - - K - - - Bacterial regulatory proteins, tetR family
HCBKCGNC_01681 3.65e-74 napB - - K - - - transcriptional
HCBKCGNC_01682 3.21e-89 mleR - - K - - - LysR family
HCBKCGNC_01683 3.4e-313 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
HCBKCGNC_01684 1.24e-161 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
HCBKCGNC_01685 1.63e-81 - - - S - - - ECF transporter, substrate-specific component
HCBKCGNC_01686 3.17e-78 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
HCBKCGNC_01687 5.57e-96 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HCBKCGNC_01688 1.28e-253 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
HCBKCGNC_01689 7.98e-49 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HCBKCGNC_01690 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HCBKCGNC_01691 5.56e-124 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HCBKCGNC_01692 2.54e-148 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HCBKCGNC_01693 6.89e-118 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HCBKCGNC_01694 5.17e-228 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
HCBKCGNC_01696 1.96e-54 - - - - - - - -
HCBKCGNC_01697 9.28e-42 - - - K - - - GNAT family
HCBKCGNC_01698 4.59e-262 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HCBKCGNC_01699 1.46e-277 gdhA 1.4.1.3, 1.4.1.4 - E ko:K00261,ko:K00262 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 ko00000,ko00001,ko00002,ko01000,ko04147 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
HCBKCGNC_01700 2.89e-43 - - - O - - - ADP-ribosylglycohydrolase
HCBKCGNC_01701 5.9e-272 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HCBKCGNC_01702 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HCBKCGNC_01703 2.38e-209 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HCBKCGNC_01704 9.63e-158 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
HCBKCGNC_01705 1.82e-243 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
HCBKCGNC_01706 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HCBKCGNC_01707 1.14e-213 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HCBKCGNC_01708 7.99e-33 - - - S - - - Domain of unknown function (DUF4828)
HCBKCGNC_01709 1.08e-160 mocA - - S - - - Oxidoreductase
HCBKCGNC_01710 1.62e-200 yfmL - - L - - - DEAD DEAH box helicase
HCBKCGNC_01713 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HCBKCGNC_01714 9.4e-126 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HCBKCGNC_01715 3.51e-270 - - - G ko:K16211 - ko00000,ko02000 Transporter, major facilitator family protein
HCBKCGNC_01716 1.76e-93 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HCBKCGNC_01717 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HCBKCGNC_01718 7.68e-109 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HCBKCGNC_01719 0.0 - - - E - - - Amino acid permease
HCBKCGNC_01720 1.22e-229 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 Thermophilic metalloprotease (M29)
HCBKCGNC_01721 1.65e-214 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HCBKCGNC_01722 2.43e-90 - - - K - - - Sugar-specific transcriptional regulator TrmB
HCBKCGNC_01723 1.31e-154 - - - S - - - Sulfite exporter TauE/SafE
HCBKCGNC_01724 9.8e-152 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
HCBKCGNC_01725 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HCBKCGNC_01726 5.64e-69 gtcA - - S - - - Teichoic acid glycosylation protein
HCBKCGNC_01727 2.18e-69 ykuP - - C ko:K03839 - ko00000 Flavodoxin
HCBKCGNC_01728 3.03e-183 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
HCBKCGNC_01729 5.63e-195 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HCBKCGNC_01730 2.24e-16 - 3.5.1.28 CBM50 M ko:K22409 - ko00000,ko01000 Lysin motif
HCBKCGNC_01731 5.69e-120 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HCBKCGNC_01732 1.4e-38 - - - S - - - Belongs to the HesB IscA family
HCBKCGNC_01733 1.38e-83 icaB - - G - - - Polysaccharide deacetylase
HCBKCGNC_01735 2.83e-66 - - - K - - - LysR substrate binding domain
HCBKCGNC_01736 1.66e-152 - - - S - - - Conserved hypothetical protein 698
HCBKCGNC_01737 2.06e-253 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
HCBKCGNC_01738 3.78e-138 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCBKCGNC_01739 8.2e-65 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HCBKCGNC_01740 2.29e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
HCBKCGNC_01741 1.1e-257 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HCBKCGNC_01742 8.98e-202 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HCBKCGNC_01743 4.51e-27 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
HCBKCGNC_01744 3.96e-192 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HCBKCGNC_01745 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCBKCGNC_01746 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCBKCGNC_01747 7.37e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HCBKCGNC_01748 6.48e-89 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HCBKCGNC_01749 3.82e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HCBKCGNC_01750 4.29e-140 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
HCBKCGNC_01751 9.4e-148 - - - S - - - Glycosyl transferase family 2
HCBKCGNC_01752 2.26e-81 - - - D - - - peptidase
HCBKCGNC_01753 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HCBKCGNC_01754 1.3e-48 - - - S - - - Protein of unknown function (DUF1211)
HCBKCGNC_01756 5.27e-53 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HCBKCGNC_01757 3.25e-307 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HCBKCGNC_01758 5.01e-22 yneR - - - - - - -
HCBKCGNC_01759 7.19e-290 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HCBKCGNC_01760 7.54e-284 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
HCBKCGNC_01761 3.32e-136 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HCBKCGNC_01762 1.05e-191 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HCBKCGNC_01763 1.12e-11 yobS - - K - - - Bacterial regulatory proteins, tetR family
HCBKCGNC_01764 8.94e-141 - - - U ko:K05340 - ko00000,ko02000 sugar transport
HCBKCGNC_01765 3.74e-212 - - - S - - - Putative threonine/serine exporter
HCBKCGNC_01766 6.27e-90 - - - J - - - Acetyltransferase (GNAT) domain
HCBKCGNC_01767 4.69e-121 yicL - - EG - - - EamA-like transporter family
HCBKCGNC_01768 7.89e-279 pepF - - E - - - Oligopeptidase F
HCBKCGNC_01769 2.04e-137 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HCBKCGNC_01770 2.01e-224 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HCBKCGNC_01771 4.63e-175 - 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
HCBKCGNC_01772 2.06e-80 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HCBKCGNC_01773 2.51e-31 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
HCBKCGNC_01775 1.06e-216 - - - S - - - Putative peptidoglycan binding domain
HCBKCGNC_01776 4.68e-41 - - - K - - - Transcriptional regulator, MarR family
HCBKCGNC_01777 3.56e-268 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HCBKCGNC_01778 1.11e-286 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
HCBKCGNC_01780 3.56e-106 - - - S ko:K19175 - ko00000,ko02048 Domain of unknown function DUF87
HCBKCGNC_01782 5.63e-108 yxeH - - S - - - hydrolase
HCBKCGNC_01783 2.43e-151 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HCBKCGNC_01784 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HCBKCGNC_01785 7.57e-126 yycH - - S - - - YycH protein
HCBKCGNC_01786 3.35e-100 yycI - - S - - - YycH protein
HCBKCGNC_01787 4.78e-41 - - - S - - - YjbR
HCBKCGNC_01788 1.46e-147 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
HCBKCGNC_01789 2.33e-187 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
HCBKCGNC_01790 7.88e-94 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HCBKCGNC_01791 2.65e-52 - - - GM - - - NAD(P)H-binding
HCBKCGNC_01792 3.67e-34 - - - K - - - MarR family transcriptional regulator
HCBKCGNC_01793 5.45e-112 - - - GM - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HCBKCGNC_01794 7.15e-58 - - - S - - - PD-(D/E)XK nuclease family transposase
HCBKCGNC_01795 5.59e-262 glpT - - G ko:K02445 - ko00000,ko02000 glycerol-3-phosphate transporter
HCBKCGNC_01796 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HCBKCGNC_01797 3.45e-36 ykuJ - - S - - - Protein of unknown function (DUF1797)
HCBKCGNC_01798 1.45e-164 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HCBKCGNC_01799 1.84e-163 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HCBKCGNC_01800 2.56e-203 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HCBKCGNC_01801 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HCBKCGNC_01802 5.69e-49 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
HCBKCGNC_01803 1.5e-22 - - - - - - - -
HCBKCGNC_01804 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
HCBKCGNC_01805 1.24e-31 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
HCBKCGNC_01806 6.64e-131 - - - G - - - MucBP domain
HCBKCGNC_01807 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HCBKCGNC_01808 4.92e-252 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HCBKCGNC_01809 1.26e-207 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HCBKCGNC_01810 1.07e-225 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HCBKCGNC_01811 3.21e-139 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HCBKCGNC_01812 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HCBKCGNC_01813 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 -beta-galactosidase
HCBKCGNC_01814 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HCBKCGNC_01815 1.97e-146 tagH 3.6.3.40 - GM ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HCBKCGNC_01816 3.8e-201 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HCBKCGNC_01817 8.16e-135 yueF - - S - - - AI-2E family transporter
HCBKCGNC_01818 9.74e-126 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
HCBKCGNC_01819 1.81e-241 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCBKCGNC_01820 2.25e-79 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
HCBKCGNC_01822 3.59e-29 - - - S - - - Cytochrome B5
HCBKCGNC_01823 2.05e-53 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HCBKCGNC_01824 3.5e-31 - - - - - - - -
HCBKCGNC_01825 6.13e-17 - - - - - - - -
HCBKCGNC_01826 3.12e-57 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HCBKCGNC_01827 8.08e-197 yngD - - S ko:K07097 - ko00000 DHHA1 domain
HCBKCGNC_01828 9.14e-117 yunF - - F - - - Protein of unknown function DUF72
HCBKCGNC_01829 5e-64 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HCBKCGNC_01831 7.6e-182 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HCBKCGNC_01832 1.5e-40 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HCBKCGNC_01833 1.32e-282 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HCBKCGNC_01834 2.32e-224 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HCBKCGNC_01835 2.99e-81 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
HCBKCGNC_01836 7.55e-78 yciB - - M - - - ErfK YbiS YcfS YnhG
HCBKCGNC_01838 2.54e-105 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HCBKCGNC_01839 2.89e-229 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HCBKCGNC_01841 3.5e-99 - - - S - - - Cell surface protein
HCBKCGNC_01843 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
HCBKCGNC_01844 1.29e-78 - - - - - - - -
HCBKCGNC_01845 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HCBKCGNC_01846 1.93e-240 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HCBKCGNC_01847 4.42e-253 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCBKCGNC_01849 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HCBKCGNC_01850 1.75e-57 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HCBKCGNC_01851 1.8e-32 ywiB - - S - - - Domain of unknown function (DUF1934)
HCBKCGNC_01852 4.97e-110 - - - F - - - glutamine amidotransferase
HCBKCGNC_01853 6.95e-261 ywfO - - S ko:K06885 - ko00000 HD domain protein
HCBKCGNC_01854 7.11e-111 - - - S - - - hydrolase
HCBKCGNC_01855 3.72e-133 - - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
HCBKCGNC_01857 5.97e-49 - - - - - - - -
HCBKCGNC_01858 7.61e-86 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HCBKCGNC_01859 1.29e-79 - - - K - - - Transcriptional regulator, MarR family
HCBKCGNC_01860 3e-129 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HCBKCGNC_01861 1.48e-36 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCBKCGNC_01862 2.98e-131 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
HCBKCGNC_01863 1.09e-125 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HCBKCGNC_01864 5.79e-247 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HCBKCGNC_01865 2.34e-60 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HCBKCGNC_01866 5.39e-83 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HCBKCGNC_01867 2.06e-274 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
HCBKCGNC_01868 3.3e-160 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HCBKCGNC_01869 4.27e-130 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
HCBKCGNC_01870 7.35e-140 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HCBKCGNC_01871 3.82e-291 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HCBKCGNC_01872 2.1e-305 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HCBKCGNC_01873 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HCBKCGNC_01874 1.05e-152 gla - - U ko:K02440 - ko00000,ko02000 Major intrinsic protein
HCBKCGNC_01875 3.09e-59 ykuL - - S - - - CBS domain
HCBKCGNC_01876 1.39e-91 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HCBKCGNC_01877 5.76e-224 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HCBKCGNC_01878 2.42e-117 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
HCBKCGNC_01880 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HCBKCGNC_01881 2.92e-28 yheA - - S - - - Belongs to the UPF0342 family
HCBKCGNC_01882 6.56e-163 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
HCBKCGNC_01883 1.22e-144 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HCBKCGNC_01885 3.15e-69 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
HCBKCGNC_01886 4.7e-121 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HCBKCGNC_01887 1.59e-87 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HCBKCGNC_01888 3.39e-125 ytmP - - M - - - Choline/ethanolamine kinase
HCBKCGNC_01889 8.2e-131 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HCBKCGNC_01890 2.95e-59 ytpP - - CO - - - Thioredoxin
HCBKCGNC_01891 1.43e-96 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCBKCGNC_01892 2.9e-297 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HCBKCGNC_01893 1.24e-282 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HCBKCGNC_01894 6.4e-80 phaJ - - I - - - N-terminal half of MaoC dehydratase
HCBKCGNC_01895 4.37e-88 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HCBKCGNC_01896 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HCBKCGNC_01897 1.04e-137 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HCBKCGNC_01898 2.15e-62 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HCBKCGNC_01899 1.04e-85 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HCBKCGNC_01900 2.46e-95 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
HCBKCGNC_01901 1.15e-136 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HCBKCGNC_01902 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HCBKCGNC_01903 1.25e-102 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HCBKCGNC_01904 4.44e-34 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HCBKCGNC_01905 5.01e-69 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HCBKCGNC_01906 3.33e-91 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
HCBKCGNC_01907 2.94e-229 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
HCBKCGNC_01908 1.36e-40 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
HCBKCGNC_01909 1e-98 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HCBKCGNC_01910 2.96e-92 yqeK - - H - - - Hydrolase, HD family
HCBKCGNC_01911 2.79e-65 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HCBKCGNC_01912 2.64e-103 - - - H - - - Nodulation protein S (NodS)
HCBKCGNC_01913 3.25e-153 ylbM - - S - - - Belongs to the UPF0348 family
HCBKCGNC_01914 1.58e-73 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HCBKCGNC_01915 8.93e-35 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HCBKCGNC_01916 9.97e-114 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
HCBKCGNC_01917 9.79e-120 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
HCBKCGNC_01918 6.9e-37 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
HCBKCGNC_01919 4.91e-172 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HCBKCGNC_01920 7.31e-164 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HCBKCGNC_01921 1.82e-49 - - - - - - - -
HCBKCGNC_01922 4.68e-119 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
HCBKCGNC_01923 1.89e-75 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HCBKCGNC_01924 3.15e-200 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HCBKCGNC_01925 3.59e-285 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HCBKCGNC_01926 7.69e-136 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HCBKCGNC_01928 1.46e-141 csrR - - K - - - response regulator
HCBKCGNC_01929 1.17e-217 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)