ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
DEFGHCHL_00001 1.19e-151 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DEFGHCHL_00002 1.6e-24 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
DEFGHCHL_00003 3.54e-172 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
DEFGHCHL_00004 4.27e-143 - - - - - - - -
DEFGHCHL_00005 1.61e-147 - - - - - - - -
DEFGHCHL_00006 1.45e-48 - - - S - - - Protein conserved in bacteria
DEFGHCHL_00007 3.77e-123 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DEFGHCHL_00008 1.4e-60 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
DEFGHCHL_00009 1.77e-47 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DEFGHCHL_00010 1.91e-132 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DEFGHCHL_00011 3.49e-183 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DEFGHCHL_00012 1.44e-23 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DEFGHCHL_00013 2.19e-104 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
DEFGHCHL_00014 3.64e-153 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
DEFGHCHL_00015 5.91e-65 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
DEFGHCHL_00016 4.25e-235 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
DEFGHCHL_00017 1.83e-106 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DEFGHCHL_00018 7.41e-41 ynzC - - S - - - UPF0291 protein
DEFGHCHL_00019 3.98e-36 yneF - - S ko:K09976 - ko00000 UPF0154 protein
DEFGHCHL_00020 2.28e-118 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
DEFGHCHL_00021 2.16e-58 - - - S - - - mazG nucleotide pyrophosphohydrolase
DEFGHCHL_00022 1.14e-85 yciQ - - P - - - membrane protein (DUF2207)
DEFGHCHL_00024 7.58e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
DEFGHCHL_00025 2.55e-49 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DEFGHCHL_00026 1.11e-90 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
DEFGHCHL_00027 2.47e-34 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
DEFGHCHL_00028 8.22e-203 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
DEFGHCHL_00029 2.92e-60 yqhL - - P - - - Rhodanese-like protein
DEFGHCHL_00030 6.17e-24 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
DEFGHCHL_00031 6.09e-141 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DEFGHCHL_00032 1.56e-257 ynbB - - P - - - aluminum resistance
DEFGHCHL_00033 1.3e-59 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
DEFGHCHL_00034 3.28e-312 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
DEFGHCHL_00036 6.13e-47 - 2.1.1.63 - H ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DEFGHCHL_00037 8.28e-64 manO - - S - - - Domain of unknown function (DUF956)
DEFGHCHL_00038 1.02e-147 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
DEFGHCHL_00039 8.26e-105 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DEFGHCHL_00040 2.86e-134 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DEFGHCHL_00041 1.58e-131 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
DEFGHCHL_00042 2.52e-196 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
DEFGHCHL_00043 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DEFGHCHL_00044 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DEFGHCHL_00045 1.16e-85 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
DEFGHCHL_00046 1.25e-216 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
DEFGHCHL_00047 3.32e-53 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
DEFGHCHL_00048 2.85e-35 ylxQ - - J - - - ribosomal protein
DEFGHCHL_00049 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DEFGHCHL_00050 6.33e-74 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DEFGHCHL_00051 1.16e-151 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DEFGHCHL_00052 7.4e-120 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
DEFGHCHL_00053 1.51e-165 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DEFGHCHL_00054 3.65e-75 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DEFGHCHL_00055 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
DEFGHCHL_00056 5.74e-218 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DEFGHCHL_00057 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DEFGHCHL_00059 8.61e-258 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
DEFGHCHL_00060 7.44e-153 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
DEFGHCHL_00061 1.83e-41 - - - - - - - -
DEFGHCHL_00062 2.52e-139 ampC - - V - - - Beta-lactamase
DEFGHCHL_00063 9.35e-141 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
DEFGHCHL_00064 1.79e-278 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
DEFGHCHL_00065 1.19e-111 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
DEFGHCHL_00066 5.99e-230 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DEFGHCHL_00067 7.51e-114 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DEFGHCHL_00068 1.9e-171 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DEFGHCHL_00069 8.89e-129 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DEFGHCHL_00070 2.33e-124 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
DEFGHCHL_00071 1.39e-27 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DEFGHCHL_00072 2.96e-57 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DEFGHCHL_00073 1.62e-73 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DEFGHCHL_00074 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DEFGHCHL_00075 3.29e-181 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DEFGHCHL_00076 8.04e-313 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DEFGHCHL_00077 3.59e-69 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
DEFGHCHL_00078 8.32e-21 ywzB - - S - - - Protein of unknown function (DUF1146)
DEFGHCHL_00079 2.53e-261 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DEFGHCHL_00080 2.82e-214 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
DEFGHCHL_00081 3.25e-36 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
DEFGHCHL_00082 2.21e-19 - - - S - - - Protein of unknown function (DUF2969)
DEFGHCHL_00083 8.97e-236 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
DEFGHCHL_00084 9.86e-36 spxA 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
DEFGHCHL_00085 4.4e-119 - - - M - - - Phosphotransferase enzyme family
DEFGHCHL_00086 2.39e-131 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
DEFGHCHL_00087 8.22e-30 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DEFGHCHL_00088 1.87e-153 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DEFGHCHL_00089 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DEFGHCHL_00090 1.55e-177 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DEFGHCHL_00091 7.17e-192 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DEFGHCHL_00092 3.18e-115 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
DEFGHCHL_00093 3.99e-238 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
DEFGHCHL_00094 1.38e-145 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DEFGHCHL_00095 4.31e-73 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
DEFGHCHL_00096 1.33e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
DEFGHCHL_00097 7.35e-69 yloU - - S - - - Asp23 family, cell envelope-related function
DEFGHCHL_00098 3.47e-302 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
DEFGHCHL_00099 1.56e-305 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DEFGHCHL_00100 1.08e-180 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DEFGHCHL_00101 9.72e-35 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEFGHCHL_00102 4.17e-129 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DEFGHCHL_00103 1.65e-289 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
DEFGHCHL_00104 1.12e-187 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DEFGHCHL_00105 1.51e-53 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DEFGHCHL_00106 9.04e-263 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DEFGHCHL_00107 1.32e-55 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
DEFGHCHL_00108 1.99e-37 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
DEFGHCHL_00109 3.22e-74 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DEFGHCHL_00110 2.25e-144 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
DEFGHCHL_00111 4.4e-78 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
DEFGHCHL_00112 2.91e-249 - - - E ko:K03294 - ko00000 amino acid
DEFGHCHL_00113 2.49e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DEFGHCHL_00114 1.33e-43 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
DEFGHCHL_00115 2.6e-53 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DEFGHCHL_00116 2.18e-146 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEFGHCHL_00117 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DEFGHCHL_00118 0.000361 - - - S - - - Tetratricopeptide repeat
DEFGHCHL_00119 9.71e-274 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DEFGHCHL_00120 6.79e-246 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DEFGHCHL_00121 5.22e-251 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DEFGHCHL_00122 1.93e-315 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DEFGHCHL_00123 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DEFGHCHL_00124 1.47e-30 ykzG - - S - - - Belongs to the UPF0356 family
DEFGHCHL_00125 1.41e-32 - - - - - - - -
DEFGHCHL_00126 1.36e-111 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DEFGHCHL_00127 9.49e-22 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily
DEFGHCHL_00128 3.42e-31 yktA - - S - - - Belongs to the UPF0223 family
DEFGHCHL_00129 1.22e-95 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
DEFGHCHL_00130 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
DEFGHCHL_00131 2.2e-187 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
DEFGHCHL_00132 7.81e-147 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
DEFGHCHL_00133 2.92e-189 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
DEFGHCHL_00134 4.34e-126 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
DEFGHCHL_00135 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DEFGHCHL_00136 2.86e-24 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
DEFGHCHL_00137 2.14e-95 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
DEFGHCHL_00138 3.35e-65 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DEFGHCHL_00139 4.23e-166 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
DEFGHCHL_00140 6.07e-123 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
DEFGHCHL_00141 9.14e-41 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DEFGHCHL_00142 4.77e-132 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DEFGHCHL_00143 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DEFGHCHL_00144 1.24e-282 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DEFGHCHL_00145 4.9e-175 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
DEFGHCHL_00146 6.95e-96 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DEFGHCHL_00147 6.93e-292 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
DEFGHCHL_00148 3.96e-202 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
DEFGHCHL_00149 1.23e-118 - - - S - - - Acyltransferase family
DEFGHCHL_00150 2.77e-242 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DEFGHCHL_00151 2.58e-156 - - - K - - - LysR substrate binding domain
DEFGHCHL_00153 6.94e-28 - - - - - - - -
DEFGHCHL_00154 2.81e-74 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
DEFGHCHL_00155 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
DEFGHCHL_00156 3.64e-63 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
DEFGHCHL_00157 1.71e-90 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
DEFGHCHL_00158 1.4e-185 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
DEFGHCHL_00159 4.16e-133 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
DEFGHCHL_00160 3.76e-143 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DEFGHCHL_00161 5.67e-173 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
DEFGHCHL_00162 2.53e-156 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
DEFGHCHL_00163 6.38e-120 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
DEFGHCHL_00164 1.25e-274 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
DEFGHCHL_00165 1.35e-46 ypmB - - S - - - Protein conserved in bacteria
DEFGHCHL_00166 2.59e-180 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
DEFGHCHL_00167 6.95e-300 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
DEFGHCHL_00168 8.09e-72 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
DEFGHCHL_00169 1.26e-107 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DEFGHCHL_00170 3.63e-101 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEFGHCHL_00171 1.24e-159 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
DEFGHCHL_00172 3.38e-116 - - - M - - - transferase activity, transferring glycosyl groups
DEFGHCHL_00173 6.04e-107 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
DEFGHCHL_00174 1.25e-125 - - - M - - - Glycosyltransferase like family 2
DEFGHCHL_00177 2.08e-148 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
DEFGHCHL_00178 5.93e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
DEFGHCHL_00179 1.87e-75 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
DEFGHCHL_00181 5.44e-87 - - - L - - - Phage integrase, N-terminal SAM-like domain
DEFGHCHL_00182 1.89e-142 ypjC - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
DEFGHCHL_00183 1.85e-136 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DEFGHCHL_00184 5.86e-167 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DEFGHCHL_00185 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
DEFGHCHL_00186 1.36e-200 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DEFGHCHL_00187 7.52e-74 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DEFGHCHL_00188 5.11e-171 - - - C - - - Aldo keto reductase
DEFGHCHL_00189 1.83e-31 - - - K - - - Transcriptional regulator
DEFGHCHL_00190 5.16e-135 ydhF - - S - - - Aldo keto reductase
DEFGHCHL_00192 3.49e-98 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
DEFGHCHL_00193 7.98e-69 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
DEFGHCHL_00194 1.77e-33 yozE - - S - - - Belongs to the UPF0346 family
DEFGHCHL_00195 2.54e-170 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DEFGHCHL_00196 1.67e-123 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DEFGHCHL_00197 5.03e-49 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
DEFGHCHL_00198 2.54e-40 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
DEFGHCHL_00199 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DEFGHCHL_00200 4.06e-264 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DEFGHCHL_00201 6.67e-257 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
DEFGHCHL_00202 1.17e-105 - - - K - - - Bacterial regulatory proteins, tetR family
DEFGHCHL_00203 6.46e-165 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
DEFGHCHL_00204 2.05e-255 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
DEFGHCHL_00205 4.16e-129 pgm - - G - - - Phosphoglycerate mutase family
DEFGHCHL_00206 2.03e-48 - - - S - - - repeat protein
DEFGHCHL_00207 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DEFGHCHL_00209 8.63e-20 - - - - - - - -
DEFGHCHL_00212 5.71e-110 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DEFGHCHL_00213 1.95e-88 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
DEFGHCHL_00214 3.97e-56 yodB - - K - - - Transcriptional regulator, HxlR family
DEFGHCHL_00215 7.45e-220 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DEFGHCHL_00216 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DEFGHCHL_00217 1.15e-163 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DEFGHCHL_00218 4.31e-127 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
DEFGHCHL_00219 2e-88 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DEFGHCHL_00220 5.6e-17 - - - - - - - -
DEFGHCHL_00221 1.01e-182 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
DEFGHCHL_00222 5.19e-56 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
DEFGHCHL_00223 3.09e-149 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
DEFGHCHL_00224 2.49e-96 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DEFGHCHL_00225 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DEFGHCHL_00226 2.53e-71 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DEFGHCHL_00227 1.27e-72 yjcF - - J - - - HAD-hyrolase-like
DEFGHCHL_00228 3.83e-56 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DEFGHCHL_00229 1.19e-164 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
DEFGHCHL_00230 2.49e-97 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DEFGHCHL_00231 7.51e-257 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
DEFGHCHL_00232 1.29e-141 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
DEFGHCHL_00233 1.24e-236 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
DEFGHCHL_00234 6.09e-109 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DEFGHCHL_00235 3.01e-114 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DEFGHCHL_00236 3.17e-173 - - - K - - - Transcriptional regulator
DEFGHCHL_00237 5.38e-185 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
DEFGHCHL_00238 4.04e-148 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
DEFGHCHL_00239 4.06e-218 araT1 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
DEFGHCHL_00240 3.49e-111 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
DEFGHCHL_00242 3.6e-57 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DEFGHCHL_00243 9.38e-219 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
DEFGHCHL_00244 8.9e-48 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
DEFGHCHL_00245 1.46e-34 - - - S - - - Family of unknown function (DUF5322)
DEFGHCHL_00246 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
DEFGHCHL_00247 8.73e-51 - - - - - - - -
DEFGHCHL_00250 8.31e-185 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
DEFGHCHL_00251 6.85e-98 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
DEFGHCHL_00252 3.83e-130 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DEFGHCHL_00253 1.76e-232 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
DEFGHCHL_00254 6.31e-93 - - - L - - - DNA alkylation repair enzyme
DEFGHCHL_00255 1.72e-174 - - - EG - - - EamA-like transporter family
DEFGHCHL_00256 2.75e-190 XK27_05225 - - S - - - Tetratricopeptide repeat protein
DEFGHCHL_00257 2.21e-256 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
DEFGHCHL_00258 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
DEFGHCHL_00259 1.24e-173 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
DEFGHCHL_00260 1.1e-219 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
DEFGHCHL_00261 4.92e-165 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DEFGHCHL_00262 1.21e-104 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
DEFGHCHL_00264 7.27e-119 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DEFGHCHL_00265 6.7e-201 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
DEFGHCHL_00266 5.49e-54 XK27_04120 - - S - - - Putative amino acid metabolism
DEFGHCHL_00267 5.64e-256 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DEFGHCHL_00268 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DEFGHCHL_00269 6.47e-21 - - - S - - - Protein of unknown function (DUF2929)
DEFGHCHL_00270 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
DEFGHCHL_00271 1.7e-211 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
DEFGHCHL_00272 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
DEFGHCHL_00274 6.49e-53 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
DEFGHCHL_00275 1.38e-106 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DEFGHCHL_00276 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DEFGHCHL_00277 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DEFGHCHL_00278 1.84e-246 FbpA - - K - - - Fibronectin-binding protein
DEFGHCHL_00279 2.07e-52 - - - K - - - Transcriptional regulator
DEFGHCHL_00280 4.15e-148 - - - S - - - EDD domain protein, DegV family
DEFGHCHL_00281 6.76e-92 - 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase, peptidase S26
DEFGHCHL_00282 3.4e-53 - - - S - - - ASCH
DEFGHCHL_00283 2.62e-236 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DEFGHCHL_00284 2.87e-98 - - - S - - - Calcineurin-like phosphoesterase
DEFGHCHL_00285 1.47e-116 - - - EG - - - EamA-like transporter family
DEFGHCHL_00286 4.69e-105 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-type Na efflux pump, permease component
DEFGHCHL_00287 3.45e-142 natA - - S ko:K01990 - ko00000,ko00002,ko02000 Domain of unknown function (DUF4162)
DEFGHCHL_00288 2.83e-26 - - - K - - - Psort location Cytoplasmic, score
DEFGHCHL_00290 2.02e-48 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DEFGHCHL_00291 1.17e-288 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
DEFGHCHL_00292 3.19e-220 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
DEFGHCHL_00293 3.34e-76 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Low molecular weight phosphatase family
DEFGHCHL_00294 3.32e-191 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DEFGHCHL_00295 4.73e-40 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DEFGHCHL_00296 1.94e-222 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
DEFGHCHL_00297 1.25e-275 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DEFGHCHL_00299 2.72e-114 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
DEFGHCHL_00300 8.94e-197 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DEFGHCHL_00301 5.92e-40 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
DEFGHCHL_00302 2.42e-88 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DEFGHCHL_00303 2.07e-196 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
DEFGHCHL_00304 1.71e-105 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Ami_3
DEFGHCHL_00305 1.02e-111 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
DEFGHCHL_00306 1.79e-27 - - - M - - - Lysin motif
DEFGHCHL_00307 2.83e-157 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
DEFGHCHL_00308 5.38e-77 - - - S - - - Helix-turn-helix domain
DEFGHCHL_00309 6.24e-277 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
DEFGHCHL_00310 3.42e-59 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
DEFGHCHL_00311 4.53e-151 icaA - - M - - - Glycosyl transferase family group 2
DEFGHCHL_00312 3.3e-52 - - - - - - - -
DEFGHCHL_00313 6.77e-61 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DEFGHCHL_00314 1.29e-35 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DEFGHCHL_00316 7.63e-237 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DEFGHCHL_00317 2.39e-261 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DEFGHCHL_00318 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
DEFGHCHL_00319 4.75e-215 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
DEFGHCHL_00320 1.16e-143 - - - EGP ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
DEFGHCHL_00321 5.29e-157 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
DEFGHCHL_00322 4.84e-92 - - - K - - - Transcriptional regulator
DEFGHCHL_00323 1.33e-135 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
DEFGHCHL_00324 4.82e-89 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DEFGHCHL_00325 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
DEFGHCHL_00326 4.89e-89 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
DEFGHCHL_00327 4.74e-161 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
DEFGHCHL_00328 2.97e-129 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
DEFGHCHL_00329 1.24e-103 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
DEFGHCHL_00330 4.97e-153 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
DEFGHCHL_00331 2.06e-138 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
DEFGHCHL_00332 1.48e-31 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
DEFGHCHL_00333 5.93e-242 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DEFGHCHL_00334 2.21e-73 - - - S - - - Protein of unknown function (DUF1129)
DEFGHCHL_00335 2.14e-45 - - - - - - - -
DEFGHCHL_00336 5.14e-132 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
DEFGHCHL_00337 1.6e-126 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
DEFGHCHL_00338 4.23e-139 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
DEFGHCHL_00339 1.98e-71 - - - S - - - ECF transporter, substrate-specific component
DEFGHCHL_00340 6.05e-131 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
DEFGHCHL_00341 1.88e-114 - - - S - - - NADPH-dependent FMN reductase
DEFGHCHL_00342 8.26e-36 adhR - - K - - - transcriptional regulator
DEFGHCHL_00343 1.34e-88 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
DEFGHCHL_00345 1.04e-190 - - - EGP - - - Major Facilitator
DEFGHCHL_00346 1.03e-81 - - - S - - - Haloacid dehalogenase-like hydrolase
DEFGHCHL_00347 2.62e-114 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
DEFGHCHL_00348 1.3e-47 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
DEFGHCHL_00349 7e-149 cps3J - - M - - - Domain of unknown function (DUF4422)
DEFGHCHL_00350 1.61e-75 - - - S - - - Glycosyltransferase like family 2
DEFGHCHL_00351 1.45e-79 - - - S - - - Glycosyltransferase like family 2
DEFGHCHL_00352 1.71e-184 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DEFGHCHL_00353 2.26e-130 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
DEFGHCHL_00354 2.56e-213 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DEFGHCHL_00355 3.15e-161 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
DEFGHCHL_00356 7.12e-147 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
DEFGHCHL_00358 9.26e-109 tcaA - - S ko:K21463 - ko00000 response to antibiotic
DEFGHCHL_00360 1.73e-219 wchF - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
DEFGHCHL_00361 1.17e-146 - - - G - - - Glycosyltransferase Family 4
DEFGHCHL_00362 9.62e-82 - - - S - - - Hexapeptide repeat of succinyl-transferase
DEFGHCHL_00363 3.41e-178 - - - M - - - Glycosyl transferase family 2
DEFGHCHL_00364 5.01e-05 yibD - GT2 M ko:K19354 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferases involved in cell wall biogenesis
DEFGHCHL_00366 6.97e-52 - - - M - - - Glycosyltransferase like family 2
DEFGHCHL_00367 1.52e-18 - - - S - - - Hexapeptide repeat of succinyl-transferase
DEFGHCHL_00368 4.66e-163 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
DEFGHCHL_00369 2.24e-51 - - - S - - - Acyltransferase family
DEFGHCHL_00371 4.01e-270 ugd 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 UDP binding domain
DEFGHCHL_00372 2.84e-98 epsB - - M - - - biosynthesis protein
DEFGHCHL_00373 3.85e-118 ywqD - - D - - - Capsular exopolysaccharide family
DEFGHCHL_00374 5.99e-142 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
DEFGHCHL_00375 1.15e-162 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
DEFGHCHL_00376 5.92e-116 epsE2 - - M - - - Bacterial sugar transferase
DEFGHCHL_00377 5.92e-120 - - - M - - - Core-2/I-Branching enzyme
DEFGHCHL_00378 9.57e-248 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
DEFGHCHL_00379 1.12e-62 - - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase, family 2
DEFGHCHL_00380 2.62e-202 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
DEFGHCHL_00381 2.69e-68 - - - - - - - -
DEFGHCHL_00382 1.31e-91 - - - M - - - transferase activity, transferring glycosyl groups
DEFGHCHL_00383 2.35e-80 - - - D - - - Peptidase family M23
DEFGHCHL_00385 1.55e-208 - - - C - - - Luciferase-like monooxygenase
DEFGHCHL_00386 6.93e-55 hxlR - - K - - - Transcriptional regulator, HxlR family
DEFGHCHL_00387 6.68e-219 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
DEFGHCHL_00388 8.92e-134 gntR - - K - - - UbiC transcription regulator-associated domain protein
DEFGHCHL_00389 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
DEFGHCHL_00390 5.94e-107 pncA - - Q - - - isochorismatase
DEFGHCHL_00391 1.14e-81 pgm1 - - G - - - phosphoglycerate mutase
DEFGHCHL_00392 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DEFGHCHL_00393 1.68e-108 treR - - K ko:K03486 - ko00000,ko03000 UTRA
DEFGHCHL_00394 8.27e-316 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
DEFGHCHL_00395 1.18e-212 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
DEFGHCHL_00397 3.99e-227 XK27_08315 - - M - - - Sulfatase
DEFGHCHL_00398 1.87e-65 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
DEFGHCHL_00399 4.64e-113 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DEFGHCHL_00400 2.54e-214 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
DEFGHCHL_00401 2.1e-161 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DEFGHCHL_00402 8.47e-223 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
DEFGHCHL_00403 1.49e-97 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DEFGHCHL_00404 1.84e-187 XK27_08315 - - M - - - Sulfatase
DEFGHCHL_00405 4.93e-148 - - - S - - - Bacterial membrane protein YfhO
DEFGHCHL_00406 1.06e-120 - - - S - - - Bacterial membrane protein, YfhO
DEFGHCHL_00407 4.72e-09 - - - S - - - Psort location CytoplasmicMembrane, score
DEFGHCHL_00408 2.69e-53 - - - S - - - Bacterial membrane protein, YfhO
DEFGHCHL_00409 4.55e-20 - - - - - - - -
DEFGHCHL_00410 3e-36 - - - S - - - Psort location CytoplasmicMembrane, score
DEFGHCHL_00411 8.65e-185 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
DEFGHCHL_00412 2.11e-67 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
DEFGHCHL_00413 1.19e-195 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
DEFGHCHL_00414 8.69e-86 - - - S - - - NADPH-dependent FMN reductase
DEFGHCHL_00415 1.06e-118 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
DEFGHCHL_00416 4.6e-205 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
DEFGHCHL_00417 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
DEFGHCHL_00418 5.12e-39 gtcA - - S - - - Teichoic acid glycosylation protein
DEFGHCHL_00419 2.86e-145 - - - M - - - Glycosyl transferase family 2
DEFGHCHL_00420 2.32e-28 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
DEFGHCHL_00421 1.33e-95 - - - - - - - -
DEFGHCHL_00422 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
DEFGHCHL_00423 2.25e-170 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
DEFGHCHL_00424 1.12e-55 - - - E - - - GDSL-like Lipase/Acylhydrolase
DEFGHCHL_00425 3.91e-143 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
DEFGHCHL_00426 2.45e-241 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
DEFGHCHL_00427 1.26e-268 potE - - E - - - Amino Acid
DEFGHCHL_00428 1.24e-43 - - - S - - - MazG nucleotide pyrophosphohydrolase domain
DEFGHCHL_00429 5.37e-169 tetA - - EGP ko:K08151,ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko01504,ko02000 Major facilitator Superfamily
DEFGHCHL_00431 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
DEFGHCHL_00432 9.07e-86 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
DEFGHCHL_00433 1.18e-258 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
DEFGHCHL_00434 6.89e-82 - - - C - - - FMN binding
DEFGHCHL_00435 4.09e-291 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DEFGHCHL_00437 4.97e-199 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DEFGHCHL_00438 2e-77 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
DEFGHCHL_00439 5.3e-12 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
DEFGHCHL_00440 1.67e-104 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
DEFGHCHL_00441 2.41e-127 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
DEFGHCHL_00442 2.6e-166 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cobalamin-independent synthase, Catalytic domain
DEFGHCHL_00443 1.14e-92 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
DEFGHCHL_00444 1.2e-248 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
DEFGHCHL_00445 2.56e-203 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
DEFGHCHL_00446 1.6e-70 oxyR5 - - K - - - Transcriptional regulator
DEFGHCHL_00447 8.83e-243 - - - C - - - FMN_bind
DEFGHCHL_00448 1.03e-148 pepL 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
DEFGHCHL_00449 2.42e-254 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
DEFGHCHL_00450 8e-176 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
DEFGHCHL_00451 4.75e-102 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
DEFGHCHL_00452 1.32e-84 - - - G - - - PTS system sorbose subfamily IIB component
DEFGHCHL_00453 7.67e-139 - - - G - - - PTS system sorbose-specific iic component
DEFGHCHL_00454 1.68e-157 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
DEFGHCHL_00455 2.02e-51 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
DEFGHCHL_00456 2.06e-291 treC - - G - - - Psort location Cytoplasmic, score
DEFGHCHL_00457 1.41e-142 - - - K - - - helix_turn _helix lactose operon repressor
DEFGHCHL_00458 9.64e-168 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
DEFGHCHL_00459 2.64e-98 - - - S - - - intracellular protease amidase
DEFGHCHL_00460 1.12e-28 - - - K - - - transcriptional regulator
DEFGHCHL_00461 3.55e-190 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
DEFGHCHL_00462 5.2e-57 - - - S - - - Cupredoxin-like domain
DEFGHCHL_00463 4.15e-26 - - - S - - - Cupredoxin-like domain
DEFGHCHL_00464 1.95e-316 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
DEFGHCHL_00465 3.17e-78 pgm3 - - G - - - phosphoglycerate mutase family
DEFGHCHL_00466 1.14e-69 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
DEFGHCHL_00467 6.95e-112 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DEFGHCHL_00468 1.85e-278 yifK - - E ko:K03293 - ko00000 Amino acid permease
DEFGHCHL_00469 1.53e-254 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
DEFGHCHL_00470 1.39e-189 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEFGHCHL_00471 1.06e-216 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEFGHCHL_00472 3.5e-229 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
DEFGHCHL_00473 1.99e-196 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
DEFGHCHL_00474 5.22e-21 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
DEFGHCHL_00475 9.59e-265 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
DEFGHCHL_00476 1.53e-143 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
DEFGHCHL_00477 2.35e-51 - - - K - - - LytTr DNA-binding domain
DEFGHCHL_00479 2.6e-191 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
DEFGHCHL_00480 4.63e-30 - - - K - - - Transcriptional regulator C-terminal region
DEFGHCHL_00481 2.53e-60 - - - S - - - Short repeat of unknown function (DUF308)
DEFGHCHL_00482 5.58e-69 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DEFGHCHL_00483 3e-208 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
DEFGHCHL_00484 4.78e-86 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter
DEFGHCHL_00485 1.78e-130 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
DEFGHCHL_00486 1.22e-57 ytcD - - K - - - HxlR-like helix-turn-helix
DEFGHCHL_00487 5.75e-155 ytbE - - S - - - reductase
DEFGHCHL_00488 1.11e-93 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DEFGHCHL_00489 2.78e-54 - - - K - - - Acetyltransferase GNAT Family
DEFGHCHL_00490 1.37e-61 hmpT - - S - - - ECF-type riboflavin transporter, S component
DEFGHCHL_00491 1.26e-84 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
DEFGHCHL_00492 3.07e-06 sdpI - - S - - - Protein of unknown function (DUF1648)
DEFGHCHL_00493 7.86e-140 dat 2.6.1.21 - EH ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 PFAM aminotransferase, class IV
DEFGHCHL_00494 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
DEFGHCHL_00495 3.54e-59 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
DEFGHCHL_00496 4.55e-68 - - - K - - - Transcriptional regulator C-terminal region
DEFGHCHL_00497 1.8e-69 jag - - S ko:K06346 - ko00000 R3H domain protein
DEFGHCHL_00498 2.21e-73 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
DEFGHCHL_00499 1.42e-42 - - - S - - - Branched-chain amino acid transport protein (AzlD)
DEFGHCHL_00500 1.4e-96 azlC - - E - - - branched-chain amino acid
DEFGHCHL_00501 3.96e-76 - - - F - - - Nucleoside 2-deoxyribosyltransferase
DEFGHCHL_00502 7.04e-149 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
DEFGHCHL_00503 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
DEFGHCHL_00504 1.89e-45 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
DEFGHCHL_00505 2.17e-240 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
DEFGHCHL_00506 1.85e-96 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
DEFGHCHL_00507 5.69e-142 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
DEFGHCHL_00509 1.23e-265 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
DEFGHCHL_00510 8.21e-78 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
DEFGHCHL_00511 5.15e-145 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
DEFGHCHL_00512 2.16e-192 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
DEFGHCHL_00513 2.82e-88 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
DEFGHCHL_00514 4.88e-66 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
DEFGHCHL_00515 3.08e-135 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
DEFGHCHL_00516 2.84e-220 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
DEFGHCHL_00517 2.7e-258 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
DEFGHCHL_00518 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DEFGHCHL_00519 1.44e-236 noxE - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
DEFGHCHL_00520 1.66e-51 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
DEFGHCHL_00522 3.9e-134 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
DEFGHCHL_00523 7.11e-129 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
DEFGHCHL_00524 9.62e-122 fliY - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
DEFGHCHL_00525 3.75e-49 - - - K - - - Transcriptional regulator
DEFGHCHL_00526 6.4e-138 - - - P - - - Integral membrane protein TerC family
DEFGHCHL_00527 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
DEFGHCHL_00528 1.63e-85 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DEFGHCHL_00529 2.44e-235 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
DEFGHCHL_00530 5.09e-56 - - - K - - - Transcriptional regulator, GntR family
DEFGHCHL_00531 1.09e-121 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DEFGHCHL_00533 4.21e-53 ybjQ - - S - - - Belongs to the UPF0145 family
DEFGHCHL_00534 2.83e-199 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
DEFGHCHL_00535 1.28e-122 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DEFGHCHL_00536 2.46e-198 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DEFGHCHL_00537 3.93e-180 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DEFGHCHL_00538 5e-45 - - - - - - - -
DEFGHCHL_00539 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
DEFGHCHL_00540 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
DEFGHCHL_00541 5.09e-83 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
DEFGHCHL_00543 8.59e-94 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
DEFGHCHL_00544 1.47e-78 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Possible lysine decarboxylase
DEFGHCHL_00545 2.8e-15 - - - GKT - - - COG3711 Transcriptional antiterminator
DEFGHCHL_00546 5.96e-74 yvbG - - U ko:K05595 - ko00000,ko02000 MarC family integral membrane protein
DEFGHCHL_00547 3.31e-231 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
DEFGHCHL_00548 5.17e-63 - - - S - - - Membrane
DEFGHCHL_00549 1.8e-94 - - - K - - - helix_turn_helix, arabinose operon control protein
DEFGHCHL_00550 4.7e-239 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
DEFGHCHL_00551 1.26e-272 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
DEFGHCHL_00552 8.21e-53 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
DEFGHCHL_00553 2.46e-277 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
DEFGHCHL_00554 2.63e-140 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
DEFGHCHL_00556 7.06e-27 - - - S - - - YjcQ protein
DEFGHCHL_00557 3.81e-134 - - - L - - - Belongs to the 'phage' integrase family
DEFGHCHL_00559 3.1e-64 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
DEFGHCHL_00560 3.85e-36 - - - K - - - Cro/C1-type HTH DNA-binding domain
DEFGHCHL_00561 1.17e-103 - - - S - - - Putative inner membrane protein (DUF1819)
DEFGHCHL_00562 8.69e-89 - - - S - - - Domain of unknown function (DUF1788)
DEFGHCHL_00563 0.0 - - - K - - - RNA-binding protein homologous to eukaryotic snRNP
DEFGHCHL_00564 0.0 - - - V - - - restriction
DEFGHCHL_00565 0.0 - - - S - - - TIGR02687 family
DEFGHCHL_00566 0.0 - 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 Putative ATP-dependent Lon protease
DEFGHCHL_00567 7.01e-56 - - - - - - - -
DEFGHCHL_00568 1.9e-48 - - - - - - - -
DEFGHCHL_00571 2.61e-16 - - - - - - - -
DEFGHCHL_00574 3.88e-215 potE2 - - E ko:K03294 - ko00000 amino acid
DEFGHCHL_00575 2.58e-184 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
DEFGHCHL_00576 1.29e-146 queH 1.17.99.6 - C ko:K09765 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DEFGHCHL_00577 7.61e-74 - - - K - - - Domain of unknown function (DUF1836)
DEFGHCHL_00578 2.16e-100 yitS - - S - - - EDD domain protein, DegV family
DEFGHCHL_00579 1.25e-31 - - - K - - - Cro/C1-type HTH DNA-binding domain
DEFGHCHL_00580 7.8e-38 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
DEFGHCHL_00581 8.19e-62 - - - S - - - ORF6N domain
DEFGHCHL_00587 2.36e-30 - - - S - - - Bacteriophage Mu Gam like protein
DEFGHCHL_00589 2.69e-94 - - - S - - - AAA domain
DEFGHCHL_00590 9.53e-42 - - - S - - - Protein of unknown function (DUF669)
DEFGHCHL_00591 5.72e-119 - - - S - - - Putative HNHc nuclease
DEFGHCHL_00592 7.03e-48 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
DEFGHCHL_00593 3.65e-158 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 DnaB-like helicase C terminal domain
DEFGHCHL_00595 1.66e-52 - - - S - - - Protein of unknown function (DUF1064)
DEFGHCHL_00597 1.03e-52 - - - S - - - Protein of unknown function (DUF1064)
DEFGHCHL_00602 1.64e-40 - - - S - - - Phage transcriptional regulator, ArpU family
DEFGHCHL_00606 3.81e-29 - - - - - - - -
DEFGHCHL_00607 1.71e-90 - - - L - - - HNH nucleases
DEFGHCHL_00608 2.89e-105 - - - L - - - Phage terminase, small subunit
DEFGHCHL_00609 0.0 - - - S - - - Phage Terminase
DEFGHCHL_00611 1.75e-257 - - - S - - - Phage portal protein
DEFGHCHL_00612 8.22e-153 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
DEFGHCHL_00613 2.32e-279 - - - S - - - Phage capsid family
DEFGHCHL_00614 4.39e-29 - - - S - - - Phage gp6-like head-tail connector protein
DEFGHCHL_00615 5.23e-77 - - - S - - - Phage head-tail joining protein
DEFGHCHL_00616 2.21e-70 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
DEFGHCHL_00617 8.11e-73 - - - S - - - Protein of unknown function (DUF806)
DEFGHCHL_00618 6.88e-98 - - - S - - - Phage tail tube protein
DEFGHCHL_00619 1.05e-23 - - - S - - - Phage tail assembly chaperone proteins, TAC
DEFGHCHL_00621 0.0 - - - L - - - Phage tail tape measure protein TP901
DEFGHCHL_00622 8.81e-100 - - - S - - - Phage tail protein
DEFGHCHL_00623 2.3e-156 rny - - D ko:K12088,ko:K18682 ko03018,ko05120,map03018,map05120 ko00000,ko00001,ko00002,ko01000,ko02044,ko03019 peptidase
DEFGHCHL_00625 4.22e-31 - - - S - - - Calcineurin-like phosphoesterase
DEFGHCHL_00630 4.34e-13 - - - S - - - Bacteriophage holin
DEFGHCHL_00631 3.28e-165 - - - M - - - Glycosyl hydrolases family 25
DEFGHCHL_00637 3.58e-273 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
DEFGHCHL_00638 1.53e-61 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
DEFGHCHL_00639 1.87e-85 coiA - - S ko:K06198 - ko00000 Competence protein
DEFGHCHL_00640 3.54e-288 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
DEFGHCHL_00641 1.01e-53 yjbH - - Q - - - Thioredoxin
DEFGHCHL_00642 1.76e-124 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
DEFGHCHL_00643 2.58e-150 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
DEFGHCHL_00644 6.71e-155 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
DEFGHCHL_00645 7.48e-147 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DEFGHCHL_00646 5.27e-148 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DEFGHCHL_00647 6.44e-73 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
DEFGHCHL_00648 1.21e-188 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
DEFGHCHL_00649 1.39e-100 - - - S - - - VIT family
DEFGHCHL_00650 2.71e-107 - - - S - - - membrane
DEFGHCHL_00651 1.97e-53 - - - K - - - Domain of unknown function (DUF1836)
DEFGHCHL_00652 8.68e-83 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
DEFGHCHL_00653 3.39e-47 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
DEFGHCHL_00654 3.43e-96 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DEFGHCHL_00656 6.19e-10 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DEFGHCHL_00658 9.17e-219 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
DEFGHCHL_00659 1.26e-202 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
DEFGHCHL_00660 4.81e-54 - - - S - - - VanZ like family
DEFGHCHL_00661 4e-153 yebC - - K - - - Transcriptional regulatory protein
DEFGHCHL_00662 4.05e-130 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEFGHCHL_00663 5.53e-153 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
DEFGHCHL_00664 7.88e-122 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
DEFGHCHL_00665 4.34e-36 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
DEFGHCHL_00666 7.13e-18 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
DEFGHCHL_00670 1.41e-123 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
DEFGHCHL_00671 3.13e-239 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
DEFGHCHL_00672 9.2e-73 - - - S - - - Calcineurin-like phosphoesterase
DEFGHCHL_00673 4.29e-77 yutD - - S - - - Protein of unknown function (DUF1027)
DEFGHCHL_00674 3.4e-145 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DEFGHCHL_00675 4.54e-38 - - - S - - - Protein of unknown function (DUF1461)
DEFGHCHL_00676 3.79e-118 dedA - - S ko:K03975 - ko00000 SNARE associated Golgi protein
DEFGHCHL_00677 1.63e-118 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
DEFGHCHL_00678 2.55e-65 yugI - - J ko:K07570 - ko00000 general stress protein
DEFGHCHL_00679 1.6e-262 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DEFGHCHL_00680 2.64e-308 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
DEFGHCHL_00681 3.19e-86 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
DEFGHCHL_00682 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
DEFGHCHL_00683 2.9e-14 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEFGHCHL_00684 3.04e-71 lssY 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
DEFGHCHL_00685 1.02e-105 lysR5 - - K - - - LysR substrate binding domain
DEFGHCHL_00686 3.16e-153 - - - S ko:K07090 - ko00000 membrane transporter protein
DEFGHCHL_00687 1.39e-42 - - - S - - - Protein of unknown function (DUF1634)
DEFGHCHL_00688 9.74e-159 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
DEFGHCHL_00689 2.98e-284 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
DEFGHCHL_00690 5.68e-21 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
DEFGHCHL_00691 1.44e-208 - - - EGP ko:K18934 - ko00000,ko02000 Major Facilitator Superfamily
DEFGHCHL_00692 1.18e-103 - - - S - - - L,D-transpeptidase catalytic domain
DEFGHCHL_00693 1.7e-175 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
DEFGHCHL_00694 6.07e-186 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DEFGHCHL_00695 1.86e-35 yuxO - - Q - - - Thioesterase superfamily
DEFGHCHL_00696 1.18e-69 - - - F - - - glutamine amidotransferase
DEFGHCHL_00697 2.05e-189 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
DEFGHCHL_00698 2.47e-146 degV - - S - - - EDD domain protein, DegV family
DEFGHCHL_00699 2.03e-169 cadA - - P - - - P-type ATPase
DEFGHCHL_00700 1.09e-107 cadA - - P - - - P-type ATPase
DEFGHCHL_00701 0.0 - - - E - - - Amino acid permease
DEFGHCHL_00702 2.11e-106 - - - S - - - Membrane
DEFGHCHL_00703 1.66e-57 cps3F - - - - - - -
DEFGHCHL_00704 1.22e-182 - - - Q - - - Imidazolonepropionase and related amidohydrolases
DEFGHCHL_00705 3.11e-188 - - - E - - - glutamate:sodium symporter activity
DEFGHCHL_00706 1.62e-176 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
DEFGHCHL_00707 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
DEFGHCHL_00708 2.91e-53 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
DEFGHCHL_00709 2.78e-23 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
DEFGHCHL_00711 3.58e-137 XK27_09655 - - S - - - Virulence protein RhuM family
DEFGHCHL_00712 3.58e-158 yvgN - - C - - - Aldo keto reductase
DEFGHCHL_00713 3.87e-131 - - - S ko:K07089 - ko00000 Predicted permease
DEFGHCHL_00714 1.71e-80 - - - S - - - Sulphur transport
DEFGHCHL_00715 1.15e-23 - - - O - - - Belongs to the sulfur carrier protein TusA family
DEFGHCHL_00716 2.75e-147 - - - P - - - Rhodanese Homology Domain
DEFGHCHL_00718 1.68e-291 prdA 1.21.4.1 - EJ ko:K10793 ko00330,map00330 ko00000,ko00001,ko01000 Glycine/sarcosine/betaine reductase component B subunits
DEFGHCHL_00719 6.38e-34 - - - S - - - Psort location Cytoplasmic, score
DEFGHCHL_00720 8.02e-85 prdB - - S - - - the current gene model (or a revised gene model) may contain a premature stop
DEFGHCHL_00721 2.69e-42 - - - S - - - the current gene model (or a revised gene model) may contain a premature stop
DEFGHCHL_00722 2.76e-90 - - - S - - - An automated process has identified a potential problem with this gene model
DEFGHCHL_00723 6.97e-87 - - - EJ - - - Glycine/sarcosine/betaine reductase component B subunits
DEFGHCHL_00724 3.01e-182 - 5.1.1.4 - E ko:K01777 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 Proline racemase
DEFGHCHL_00725 5.57e-123 - - - S - - - Sulfite exporter TauE/SafE
DEFGHCHL_00726 1.53e-280 - - - E - - - amino acid
DEFGHCHL_00727 2.05e-61 yedF - - O - - - Belongs to the sulfur carrier protein TusA family
DEFGHCHL_00729 4.63e-169 selB - - J ko:K03833 - ko00000,ko03012 Elongation factor SelB, winged helix
DEFGHCHL_00730 1.37e-137 - - - E - - - Serine hydroxymethyltransferase
DEFGHCHL_00731 1.12e-142 selA 2.9.1.1 - J ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
DEFGHCHL_00732 3.75e-38 - - - S - - - Iron-sulfur cluster assembly protein
DEFGHCHL_00733 3.12e-235 - - - C - - - RnfC Barrel sandwich hybrid domain
DEFGHCHL_00734 2.28e-124 selD 2.7.9.3 - E ko:K01008 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000,ko03016 AIR synthase related protein, C-terminal domain
DEFGHCHL_00735 1.31e-187 - - - S ko:K07112 - ko00000 Sulphur transport
DEFGHCHL_00736 4.23e-38 - - - O - - - Belongs to the sulfur carrier protein TusA family
DEFGHCHL_00740 1.64e-182 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DEFGHCHL_00741 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
DEFGHCHL_00742 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DEFGHCHL_00743 1.39e-204 camS - - S - - - sex pheromone
DEFGHCHL_00744 1.34e-50 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEFGHCHL_00745 5.93e-294 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DEFGHCHL_00746 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEFGHCHL_00747 5.09e-183 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
DEFGHCHL_00748 3.02e-265 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DEFGHCHL_00749 4.47e-154 - - - L ko:K07448 - ko00000,ko02048 Mrr N-terminal domain
DEFGHCHL_00751 1e-96 rha - - K - - - phage regulatory protein, rha family
DEFGHCHL_00752 4.38e-26 - - - - - - - -
DEFGHCHL_00753 3.16e-09 - - - - - - - -
DEFGHCHL_00754 5.08e-89 - - - L - - - AAA domain
DEFGHCHL_00755 3.6e-27 - - - K - - - Cro/C1-type HTH DNA-binding domain
DEFGHCHL_00756 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
DEFGHCHL_00757 1.26e-200 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 cog cog0286
DEFGHCHL_00758 1.94e-47 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
DEFGHCHL_00759 8.65e-62 - - - V - - - Type I restriction modification DNA specificity domain
DEFGHCHL_00760 3.02e-115 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DEFGHCHL_00761 9.25e-124 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
DEFGHCHL_00762 4.05e-114 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
DEFGHCHL_00763 3.1e-307 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DEFGHCHL_00764 3.23e-166 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
DEFGHCHL_00765 4e-316 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
DEFGHCHL_00766 2.41e-56 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
DEFGHCHL_00768 1.08e-147 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEFGHCHL_00769 4.29e-163 - - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
DEFGHCHL_00770 5.83e-109 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DEFGHCHL_00771 2.56e-45 - - - S - - - Enterocin A Immunity
DEFGHCHL_00772 6.03e-280 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
DEFGHCHL_00773 1.17e-25 HA62_12640 - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
DEFGHCHL_00774 4.81e-95 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
DEFGHCHL_00775 1.38e-284 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DEFGHCHL_00776 1.38e-195 yacL - - S - - - domain protein
DEFGHCHL_00777 7.38e-313 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DEFGHCHL_00778 3.05e-261 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
DEFGHCHL_00779 3.45e-73 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DEFGHCHL_00780 2.29e-139 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DEFGHCHL_00781 3.89e-92 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
DEFGHCHL_00782 3.3e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
DEFGHCHL_00783 1.78e-15 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DEFGHCHL_00784 3.13e-109 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
DEFGHCHL_00785 2.58e-88 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DEFGHCHL_00786 9.98e-150 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DEFGHCHL_00787 2.21e-97 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DEFGHCHL_00788 2.18e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DEFGHCHL_00789 6.01e-70 - - - - - - - -
DEFGHCHL_00790 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DEFGHCHL_00791 1.1e-203 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DEFGHCHL_00792 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DEFGHCHL_00793 1.81e-58 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
DEFGHCHL_00794 1.36e-37 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
DEFGHCHL_00795 3.19e-96 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
DEFGHCHL_00796 1.11e-80 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DEFGHCHL_00797 3.13e-267 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DEFGHCHL_00798 3.8e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DEFGHCHL_00799 6.62e-126 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DEFGHCHL_00800 4.16e-39 yaaL - - S - - - Protein of unknown function (DUF2508)
DEFGHCHL_00801 1.53e-83 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DEFGHCHL_00802 2.31e-105 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
DEFGHCHL_00803 3.85e-52 yabA - - L - - - Involved in initiation control of chromosome replication
DEFGHCHL_00804 2.83e-120 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DEFGHCHL_00805 9.93e-104 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
DEFGHCHL_00806 1.34e-176 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
DEFGHCHL_00807 5.25e-88 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
DEFGHCHL_00808 1.9e-19 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
DEFGHCHL_00809 5.06e-206 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DEFGHCHL_00810 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
DEFGHCHL_00811 1.52e-126 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DEFGHCHL_00812 7.13e-42 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
DEFGHCHL_00813 1.7e-46 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DEFGHCHL_00814 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DEFGHCHL_00815 0.0 - - - P ko:K12952 - ko00000,ko01000 COG COG0474 Cation transport ATPase
DEFGHCHL_00816 0.0 ydaO - - E - - - amino acid
DEFGHCHL_00817 3.75e-200 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
DEFGHCHL_00818 1.74e-158 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
DEFGHCHL_00819 4.87e-65 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
DEFGHCHL_00820 7.08e-105 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DEFGHCHL_00821 1.95e-119 yycB - - P ko:K03449 - ko00000,ko02000 Major Facilitator Superfamily
DEFGHCHL_00822 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DEFGHCHL_00823 4.56e-207 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DEFGHCHL_00824 4.95e-81 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
DEFGHCHL_00825 1.03e-110 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
DEFGHCHL_00826 5.23e-104 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DEFGHCHL_00827 1.02e-10 - - - K ko:K03973 - ko00000,ko02048,ko03000 PspC domain
DEFGHCHL_00828 2.17e-35 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
DEFGHCHL_00829 1.76e-169 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DEFGHCHL_00830 2.89e-143 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DEFGHCHL_00831 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
DEFGHCHL_00832 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DEFGHCHL_00833 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DEFGHCHL_00834 1.23e-107 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DEFGHCHL_00835 4.6e-101 - - - GM - - - NAD dependent epimerase dehydratase family protein
DEFGHCHL_00836 7.15e-161 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
DEFGHCHL_00837 9.11e-195 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
DEFGHCHL_00838 1.44e-191 whiA - - K ko:K09762 - ko00000 May be required for sporulation
DEFGHCHL_00839 2.07e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DEFGHCHL_00841 1.59e-174 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
DEFGHCHL_00842 1.19e-231 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DEFGHCHL_00843 1.99e-264 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
DEFGHCHL_00844 9.95e-165 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DEFGHCHL_00845 4.33e-298 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DEFGHCHL_00846 2.86e-167 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DEFGHCHL_00847 1.95e-134 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
DEFGHCHL_00848 8.04e-212 yclK - - T - - - Histidine kinase
DEFGHCHL_00849 5.39e-189 - - - E - - - Major Facilitator Superfamily
DEFGHCHL_00850 6.32e-224 eriC - - P ko:K03281 - ko00000 chloride
DEFGHCHL_00851 1.19e-32 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
DEFGHCHL_00852 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DEFGHCHL_00853 4.3e-91 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DEFGHCHL_00854 3.91e-53 - - - - - - - -
DEFGHCHL_00855 1.18e-148 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
DEFGHCHL_00856 1.52e-134 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DEFGHCHL_00857 7.01e-181 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
DEFGHCHL_00858 7.04e-73 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
DEFGHCHL_00859 2.74e-89 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
DEFGHCHL_00860 2.46e-145 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
DEFGHCHL_00861 3.92e-92 - - - S - - - Protein of unknown function (DUF1361)
DEFGHCHL_00862 1.95e-162 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DEFGHCHL_00863 3.21e-87 ybbR - - S - - - YbbR-like protein
DEFGHCHL_00864 1.1e-284 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DEFGHCHL_00865 1.59e-38 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
DEFGHCHL_00866 1.53e-163 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
DEFGHCHL_00867 8.5e-24 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
DEFGHCHL_00868 7e-250 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DEFGHCHL_00869 1.61e-207 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DEFGHCHL_00870 8.29e-83 - - - J ko:K03976 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
DEFGHCHL_00871 2.88e-124 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
DEFGHCHL_00872 2.62e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DEFGHCHL_00873 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
DEFGHCHL_00874 4.82e-135 ymfF - - S - - - Peptidase M16 inactive domain protein
DEFGHCHL_00875 2.81e-184 ymfH - - S - - - Peptidase M16
DEFGHCHL_00876 5.2e-116 ymfI 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
DEFGHCHL_00877 7.25e-85 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
DEFGHCHL_00878 2.09e-111 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DEFGHCHL_00879 1.84e-203 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DEFGHCHL_00880 1.78e-255 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
DEFGHCHL_00881 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DEFGHCHL_00882 1.41e-287 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DEFGHCHL_00883 2.19e-91 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DEFGHCHL_00884 1.45e-193 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DEFGHCHL_00885 2.88e-231 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DEFGHCHL_00886 1.4e-261 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DEFGHCHL_00887 1.06e-20 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
DEFGHCHL_00889 3.61e-79 uspA3 - - T - - - universal stress protein
DEFGHCHL_00891 2.06e-264 - - - E ko:K03294 - ko00000 Amino Acid
DEFGHCHL_00892 3.54e-150 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
DEFGHCHL_00893 4.95e-311 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
DEFGHCHL_00894 3.13e-85 lutC - - S ko:K00782 - ko00000 LUD domain
DEFGHCHL_00895 7.88e-184 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DEFGHCHL_00896 3.5e-18 - - - - - - - -
DEFGHCHL_00897 1.25e-153 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
DEFGHCHL_00898 4.29e-236 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DEFGHCHL_00899 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DEFGHCHL_00900 2.44e-49 yrzL - - S - - - Belongs to the UPF0297 family
DEFGHCHL_00901 3.16e-78 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DEFGHCHL_00902 4.23e-44 yrzB - - S - - - Belongs to the UPF0473 family
DEFGHCHL_00903 3.67e-17 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DEFGHCHL_00904 3.86e-20 cvpA - - S - - - Colicin V production protein
DEFGHCHL_00905 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DEFGHCHL_00906 1.23e-52 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
DEFGHCHL_00907 3.55e-79 yslB - - S - - - Protein of unknown function (DUF2507)
DEFGHCHL_00908 3.11e-94 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DEFGHCHL_00909 2.57e-53 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
DEFGHCHL_00912 2.44e-178 - 1.1.1.29 - C ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEFGHCHL_00913 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DEFGHCHL_00914 1.65e-272 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DEFGHCHL_00915 8.36e-254 oatA - - I - - - Acyltransferase
DEFGHCHL_00916 1.68e-22 - - - - - - - -
DEFGHCHL_00918 3.04e-179 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DEFGHCHL_00919 3.93e-127 yqjQ - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
DEFGHCHL_00920 1.17e-266 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
DEFGHCHL_00921 4.3e-104 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DEFGHCHL_00922 0.0 - - - S - - - membrane
DEFGHCHL_00923 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
DEFGHCHL_00924 3e-36 - - - S - - - Protein of unknown function (DUF3290)
DEFGHCHL_00925 5.95e-96 yviA - - S - - - Protein of unknown function (DUF421)
DEFGHCHL_00927 5.94e-158 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
DEFGHCHL_00928 1.48e-252 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
DEFGHCHL_00929 1.19e-69 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
DEFGHCHL_00930 6.08e-95 uspA - - T - - - universal stress protein
DEFGHCHL_00932 7.05e-242 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
DEFGHCHL_00933 4.14e-31 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
DEFGHCHL_00934 5.9e-130 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DEFGHCHL_00935 6.33e-73 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
DEFGHCHL_00936 2.45e-225 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DEFGHCHL_00937 5.87e-204 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
DEFGHCHL_00938 1.44e-248 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DEFGHCHL_00939 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DEFGHCHL_00940 2.43e-169 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
DEFGHCHL_00941 3.22e-102 radC - - L ko:K03630 - ko00000 DNA repair protein
DEFGHCHL_00942 1.96e-29 - - - K ko:K03704 - ko00000,ko03000 Cold shock
DEFGHCHL_00943 2.35e-207 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
DEFGHCHL_00944 1.64e-121 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
DEFGHCHL_00945 1.33e-70 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
DEFGHCHL_00946 3.56e-98 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
DEFGHCHL_00947 7.95e-163 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
DEFGHCHL_00948 3.02e-122 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
DEFGHCHL_00949 2.01e-115 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
DEFGHCHL_00950 3.24e-138 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
DEFGHCHL_00951 4.54e-124 ybcH - - D ko:K06889 - ko00000 Alpha beta
DEFGHCHL_00952 1.16e-05 - - - S - - - Protein of unknown function (DUF4044)
DEFGHCHL_00953 7.7e-196 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
DEFGHCHL_00955 5.35e-82 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
DEFGHCHL_00956 3.67e-180 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DEFGHCHL_00957 1.05e-13 ftsL - - D - - - Essential cell division protein
DEFGHCHL_00958 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
DEFGHCHL_00959 3.64e-172 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DEFGHCHL_00960 2.97e-233 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DEFGHCHL_00961 1.05e-195 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DEFGHCHL_00962 6.44e-76 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DEFGHCHL_00963 6.07e-240 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DEFGHCHL_00964 1.29e-228 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DEFGHCHL_00965 8.14e-43 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DEFGHCHL_00966 8.19e-27 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
DEFGHCHL_00967 5.69e-104 ylmH - - S - - - S4 domain protein
DEFGHCHL_00968 1.61e-91 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
DEFGHCHL_00969 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DEFGHCHL_00970 4.52e-131 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
DEFGHCHL_00971 8.05e-91 - - - O - - - ADP-ribosylglycohydrolase
DEFGHCHL_00973 4.26e-108 - - - C - - - Domain of unknown function (DUF4931)
DEFGHCHL_00974 7.86e-116 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
DEFGHCHL_00975 6.35e-66 - - - M - - - LysM domain protein
DEFGHCHL_00976 1.38e-25 - - - P - - - Rhodanese Homology Domain
DEFGHCHL_00977 3.05e-48 - - - M - - - LysM domain
DEFGHCHL_00978 2.32e-203 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
DEFGHCHL_00979 1.06e-243 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
DEFGHCHL_00980 5.29e-178 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
DEFGHCHL_00981 1.34e-254 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
DEFGHCHL_00982 4.26e-277 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter transmembrane region
DEFGHCHL_00983 4.59e-121 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
DEFGHCHL_00984 1.73e-134 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
DEFGHCHL_00985 6.22e-197 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
DEFGHCHL_00986 2.61e-183 pbuO_1 - - S ko:K06901 - ko00000,ko02000 Permease family
DEFGHCHL_00988 4.46e-37 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
DEFGHCHL_00989 2.76e-163 ydaJ - - G - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
DEFGHCHL_00990 4.64e-238 - - - - - - - -
DEFGHCHL_00991 5.19e-257 - - - S - - - Protein conserved in bacteria
DEFGHCHL_00992 3.38e-101 ydaM - - M - - - Glycosyl transferase family group 2
DEFGHCHL_00993 5.69e-103 ydaM - - M - - - Glycosyl transferase family group 2
DEFGHCHL_00994 0.0 - - - S - - - Bacterial cellulose synthase subunit
DEFGHCHL_00995 1.32e-152 - - - T - - - diguanylate cyclase activity
DEFGHCHL_00996 6.02e-37 - - - T - - - Putative diguanylate phosphodiesterase
DEFGHCHL_00997 2.41e-65 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
DEFGHCHL_00998 0.0 - - - L - - - Helicase C-terminal domain protein
DEFGHCHL_00999 2.8e-178 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
DEFGHCHL_01000 1.13e-122 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
DEFGHCHL_01001 1.07e-170 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
DEFGHCHL_01002 8.44e-201 - - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
DEFGHCHL_01003 8.38e-192 - - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
DEFGHCHL_01004 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
DEFGHCHL_01005 4.47e-229 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
DEFGHCHL_01006 4.15e-313 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
DEFGHCHL_01007 5.98e-131 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
DEFGHCHL_01008 2.85e-138 - - - - - - - -
DEFGHCHL_01009 5.69e-54 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
DEFGHCHL_01010 3.97e-59 - - - - - - - -
DEFGHCHL_01012 5.37e-129 - - - EGP - - - Major Facilitator
DEFGHCHL_01013 1.89e-86 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
DEFGHCHL_01014 1.76e-297 - - - EGP - - - Major Facilitator
DEFGHCHL_01015 1.67e-91 - - - H - - - ThiF family
DEFGHCHL_01016 2.25e-263 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
DEFGHCHL_01017 5.23e-124 - - - K - - - Transcriptional regulator
DEFGHCHL_01018 3.53e-32 - - - L ko:K07483 - ko00000 Transposase
DEFGHCHL_01019 5.39e-101 - - - L - - - Transposase and inactivated derivatives IS30 family
DEFGHCHL_01020 6.01e-61 B4168_4126 - - L ko:K07493 - ko00000 Transposase
DEFGHCHL_01021 3.13e-116 - - - - - - - -
DEFGHCHL_01022 1.04e-247 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
DEFGHCHL_01023 2.47e-57 ydeP - - K - - - Transcriptional regulator, HxlR family
DEFGHCHL_01024 7.43e-36 - - - - - - - -
DEFGHCHL_01025 0.0 - - - L - - - MobA MobL family protein
DEFGHCHL_01026 6.71e-36 - - - - - - - -
DEFGHCHL_01027 1.72e-54 - - - - - - - -
DEFGHCHL_01028 4.3e-158 - - - S - - - protein conserved in bacteria
DEFGHCHL_01029 1.99e-35 - - - - - - - -
DEFGHCHL_01030 1.07e-53 - - - L - - - Addiction module antitoxin, RelB DinJ family
DEFGHCHL_01031 5.58e-170 - - - S - - - Fic/DOC family
DEFGHCHL_01032 2.23e-216 repA - - S - - - Replication initiator protein A
DEFGHCHL_01033 4.18e-46 - - - - - - - -
DEFGHCHL_01034 6.36e-190 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
DEFGHCHL_01035 3.51e-74 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
DEFGHCHL_01036 2.43e-64 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
DEFGHCHL_01037 2.3e-28 - - - L - - - MULE transposase domain
DEFGHCHL_01038 1.03e-64 - - - L - - - MULE transposase domain
DEFGHCHL_01039 2.92e-169 - - - F - - - NUDIX domain
DEFGHCHL_01040 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DEFGHCHL_01041 3.4e-131 pncA - - Q - - - Isochorismatase family
DEFGHCHL_01042 3.57e-137 - - - L - - - Helix-turn-helix domain
DEFGHCHL_01043 1.28e-143 - - - L ko:K07497 - ko00000 hmm pf00665
DEFGHCHL_01044 9.8e-113 saeS 2.7.13.3 - T ko:K10681 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
DEFGHCHL_01045 1.76e-98 saeR - - K ko:K10682 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
DEFGHCHL_01047 1.38e-165 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
DEFGHCHL_01048 5.35e-235 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DEFGHCHL_01049 2.75e-199 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
DEFGHCHL_01050 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
DEFGHCHL_01051 2.47e-151 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DEFGHCHL_01053 6.91e-73 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
DEFGHCHL_01054 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DEFGHCHL_01055 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DEFGHCHL_01056 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DEFGHCHL_01057 3.5e-214 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
DEFGHCHL_01058 6.3e-271 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
DEFGHCHL_01060 7.37e-78 - - - T - - - Universal stress protein family
DEFGHCHL_01061 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
DEFGHCHL_01062 2.65e-35 - - - - - - - -
DEFGHCHL_01063 7.58e-252 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
DEFGHCHL_01064 2.14e-141 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
DEFGHCHL_01065 1.46e-106 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DEFGHCHL_01066 1.25e-186 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
DEFGHCHL_01067 1.62e-186 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
DEFGHCHL_01068 1.8e-272 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
DEFGHCHL_01069 4.34e-93 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
DEFGHCHL_01070 5.71e-28 - - - - - - - -
DEFGHCHL_01071 5.45e-130 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
DEFGHCHL_01072 3.37e-151 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEFGHCHL_01073 4.49e-57 - - - K - - - helix_turn_helix isocitrate lyase regulation
DEFGHCHL_01074 7.12e-68 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
DEFGHCHL_01075 1.08e-74 - - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
DEFGHCHL_01076 3.4e-144 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
DEFGHCHL_01077 7.87e-229 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
DEFGHCHL_01078 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DEFGHCHL_01079 1.1e-270 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
DEFGHCHL_01080 6.57e-186 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
DEFGHCHL_01081 2.39e-119 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
DEFGHCHL_01082 2.24e-16 - 3.5.1.28 CBM50 M ko:K22409 - ko00000,ko01000 Lysin motif
DEFGHCHL_01083 5.63e-195 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
DEFGHCHL_01084 3.03e-183 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
DEFGHCHL_01085 2.18e-69 ykuP - - C ko:K03839 - ko00000 Flavodoxin
DEFGHCHL_01086 5.64e-69 gtcA - - S - - - Teichoic acid glycosylation protein
DEFGHCHL_01087 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
DEFGHCHL_01088 9.8e-152 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
DEFGHCHL_01089 1.31e-154 - - - S - - - Sulfite exporter TauE/SafE
DEFGHCHL_01090 2.43e-90 - - - K - - - Sugar-specific transcriptional regulator TrmB
DEFGHCHL_01091 1.65e-214 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
DEFGHCHL_01092 1.22e-229 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 Thermophilic metalloprotease (M29)
DEFGHCHL_01093 0.0 - - - E - - - Amino acid permease
DEFGHCHL_01094 3.85e-48 - - - - - - - -
DEFGHCHL_01096 3.22e-161 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
DEFGHCHL_01097 3.71e-21 bglG - - K ko:K03488 - ko00000,ko03000 antiterminator
DEFGHCHL_01098 1.55e-110 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 .Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome down-regulated in Spo0A mutant
DEFGHCHL_01099 9.94e-44 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
DEFGHCHL_01100 1.02e-156 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
DEFGHCHL_01101 3.46e-46 - - - S - - - Replication initiator protein A (RepA) N-terminus
DEFGHCHL_01102 3.24e-142 - - - L - - - Initiator Replication protein
DEFGHCHL_01105 1.56e-46 - - - L - - - PLD-like domain
DEFGHCHL_01106 4.77e-162 - - - L - - - PLD-like domain
DEFGHCHL_01107 1.82e-100 - - - S - - - Fic/DOC family
DEFGHCHL_01108 1.66e-217 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DEFGHCHL_01109 1.46e-141 csrR - - K - - - response regulator
DEFGHCHL_01111 7.69e-136 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DEFGHCHL_01112 3.59e-285 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DEFGHCHL_01113 3.15e-200 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DEFGHCHL_01114 1.89e-75 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DEFGHCHL_01115 4.68e-119 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
DEFGHCHL_01116 1.82e-49 - - - - - - - -
DEFGHCHL_01119 9.11e-37 - - - K - - - Helix-turn-helix XRE-family like proteins
DEFGHCHL_01123 3.03e-33 - - - S - - - Domain of unknown function (DUF4352)
DEFGHCHL_01124 2.6e-40 - - - - - - - -
DEFGHCHL_01125 2.94e-99 - - - L - - - Belongs to the 'phage' integrase family
DEFGHCHL_01126 7.31e-164 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DEFGHCHL_01127 4.91e-172 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
DEFGHCHL_01128 6.9e-37 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
DEFGHCHL_01129 9.79e-120 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
DEFGHCHL_01130 9.97e-114 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
DEFGHCHL_01131 8.93e-35 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
DEFGHCHL_01132 1.58e-73 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
DEFGHCHL_01133 3.25e-153 ylbM - - S - - - Belongs to the UPF0348 family
DEFGHCHL_01134 2.64e-103 - - - H - - - Nodulation protein S (NodS)
DEFGHCHL_01135 2.79e-65 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DEFGHCHL_01136 1.2e-91 yqeK - - H - - - Hydrolase, HD family
DEFGHCHL_01137 1e-98 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DEFGHCHL_01138 1.36e-40 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
DEFGHCHL_01139 2.94e-229 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
DEFGHCHL_01140 3.33e-91 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
DEFGHCHL_01141 5.01e-69 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DEFGHCHL_01142 4.44e-34 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
DEFGHCHL_01143 1.25e-102 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DEFGHCHL_01144 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DEFGHCHL_01145 3.39e-136 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
DEFGHCHL_01146 2.46e-95 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
DEFGHCHL_01147 1.04e-85 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DEFGHCHL_01148 2.15e-62 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DEFGHCHL_01149 1.04e-137 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DEFGHCHL_01150 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEFGHCHL_01151 4.37e-88 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
DEFGHCHL_01152 6.4e-80 phaJ - - I - - - N-terminal half of MaoC dehydratase
DEFGHCHL_01153 1.24e-282 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
DEFGHCHL_01154 2.9e-297 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
DEFGHCHL_01155 1.43e-96 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DEFGHCHL_01156 2.95e-59 ytpP - - CO - - - Thioredoxin
DEFGHCHL_01157 8.2e-131 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DEFGHCHL_01158 3.39e-125 ytmP - - M - - - Choline/ethanolamine kinase
DEFGHCHL_01159 3.98e-88 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
DEFGHCHL_01160 4.7e-121 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DEFGHCHL_01161 3.15e-69 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
DEFGHCHL_01163 1.22e-144 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DEFGHCHL_01164 6.56e-163 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
DEFGHCHL_01165 2.92e-28 yheA - - S - - - Belongs to the UPF0342 family
DEFGHCHL_01166 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
DEFGHCHL_01168 2.42e-117 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
DEFGHCHL_01169 5.76e-224 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
DEFGHCHL_01170 1.39e-91 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
DEFGHCHL_01171 2.26e-59 ykuL - - S - - - CBS domain
DEFGHCHL_01172 1.05e-152 gla - - U ko:K02440 - ko00000,ko02000 Major intrinsic protein
DEFGHCHL_01173 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DEFGHCHL_01174 2.98e-305 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
DEFGHCHL_01175 3.82e-291 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DEFGHCHL_01176 7.35e-140 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
DEFGHCHL_01177 4.27e-130 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
DEFGHCHL_01178 3.3e-160 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DEFGHCHL_01179 2.06e-274 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
DEFGHCHL_01180 5.39e-83 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DEFGHCHL_01181 2.34e-60 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DEFGHCHL_01182 5.79e-247 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DEFGHCHL_01183 1.09e-125 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
DEFGHCHL_01184 2.98e-131 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
DEFGHCHL_01185 1.48e-36 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEFGHCHL_01186 3e-129 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEFGHCHL_01187 1.29e-79 - - - K - - - Transcriptional regulator, MarR family
DEFGHCHL_01188 7.61e-86 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DEFGHCHL_01189 5.97e-49 - - - - - - - -
DEFGHCHL_01191 5.57e-225 - - - S - - - Protein of unknown function DUF262
DEFGHCHL_01192 2.17e-242 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
DEFGHCHL_01193 8.94e-104 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DEFGHCHL_01194 9.74e-78 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
DEFGHCHL_01195 9.88e-244 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
DEFGHCHL_01196 4.35e-247 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
DEFGHCHL_01197 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
DEFGHCHL_01198 5.21e-226 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DEFGHCHL_01199 3.4e-259 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
DEFGHCHL_01200 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
DEFGHCHL_01202 3.91e-28 - - - F - - - Hydrolase of X-linked nucleoside diphosphate N terminal
DEFGHCHL_01203 6.25e-72 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
DEFGHCHL_01204 1.2e-87 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
DEFGHCHL_01205 8.4e-94 - - - M - - - GNAT acetyltransferase
DEFGHCHL_01215 3.95e-244 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Adenine deaminase C-terminal domain
DEFGHCHL_01216 1.13e-83 ypsA - - S - - - Belongs to the UPF0398 family
DEFGHCHL_01217 6.51e-238 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
DEFGHCHL_01218 1.17e-98 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DEFGHCHL_01219 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
DEFGHCHL_01220 3.17e-143 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
DEFGHCHL_01221 1.02e-157 yitL - - S ko:K00243 - ko00000 S1 domain
DEFGHCHL_01222 1.64e-67 - - - S - - - Protein of unknown function (DUF441)
DEFGHCHL_01223 8.84e-76 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DEFGHCHL_01224 2.3e-127 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
DEFGHCHL_01225 3.83e-79 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DEFGHCHL_01226 1.58e-74 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DEFGHCHL_01227 6.85e-49 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DEFGHCHL_01228 6.04e-275 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DEFGHCHL_01229 4.03e-102 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DEFGHCHL_01230 3.63e-155 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
DEFGHCHL_01231 1.56e-225 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
DEFGHCHL_01232 1.94e-124 ytlR - - I - - - Diacylglycerol kinase catalytic domain
DEFGHCHL_01233 2.1e-91 - - - - - - - -
DEFGHCHL_01236 1.51e-09 - - - M - - - LysM domain
DEFGHCHL_01237 4.7e-57 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
DEFGHCHL_01238 1.55e-37 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
DEFGHCHL_01239 3.02e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
DEFGHCHL_01246 3.37e-81 - - - H - - - Methyltransferase domain
DEFGHCHL_01247 4.71e-90 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
DEFGHCHL_01248 1.37e-52 - - - M - - - Acetyltransferase (GNAT) family
DEFGHCHL_01250 2.27e-29 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
DEFGHCHL_01251 2.29e-51 ybbB - - S - - - Protein of unknown function (DUF1211)
DEFGHCHL_01253 2.66e-106 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
DEFGHCHL_01254 2.25e-39 - - - S - - - CHY zinc finger
DEFGHCHL_01255 7.27e-53 ywnA - - K - - - Transcriptional regulator
DEFGHCHL_01256 8.23e-105 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
DEFGHCHL_01259 2.86e-149 - - - M - - - Glycosyl transferases group 1
DEFGHCHL_01260 1.61e-37 - - - M - - - Glycosyl transferases group 1
DEFGHCHL_01261 1.43e-08 - - - M - - - Glycosyl transferases group 1
DEFGHCHL_01262 3.52e-225 - 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DEFGHCHL_01263 1.87e-184 - 5.1.3.6 - GM ko:K08679 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 RmlD substrate binding domain
DEFGHCHL_01264 5.3e-126 - - - S - - - Psort location CytoplasmicMembrane, score
DEFGHCHL_01265 1.36e-74 - - - M - - - Glycosyl transferases group 1
DEFGHCHL_01266 9.65e-147 - - - S - - - Glycosyltransferase WbsX
DEFGHCHL_01267 5.39e-63 - - - - - - - -
DEFGHCHL_01268 1.21e-08 - - - S - - - EpsG family
DEFGHCHL_01269 4.01e-72 - - - M - - - Glycosyltransferase like family 2
DEFGHCHL_01270 1.02e-46 - - GT2 S ko:K12990 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyltransferase
DEFGHCHL_01271 6.52e-89 - - - M - - - Glycosyltransferase Family 4
DEFGHCHL_01272 9.03e-97 - - - M - - - glycosyl transferase group 1
DEFGHCHL_01273 3.26e-152 - - - M - - - Glycosyl transferases group 1
DEFGHCHL_01274 7.59e-36 - - - S ko:K19429 - ko00000,ko01000 Bacterial transferase hexapeptide (six repeats)
DEFGHCHL_01275 4.04e-99 - - - M ko:K13012 - ko00000,ko01005 Bacterial sugar transferase
DEFGHCHL_01276 2.49e-209 epsN - - M ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
DEFGHCHL_01277 7.85e-259 capD - - GM - - - Polysaccharide biosynthesis protein
DEFGHCHL_01278 1.41e-82 - - - D - - - AAA domain
DEFGHCHL_01279 9.81e-61 - - - M - - - Chain length determinant protein
DEFGHCHL_01280 1.44e-53 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
DEFGHCHL_01281 1.69e-225 rsmF - - J - - - NOL1 NOP2 sun family protein
DEFGHCHL_01282 1.17e-81 - - - - - - - -
DEFGHCHL_01283 1.84e-104 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
DEFGHCHL_01284 5.02e-144 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
DEFGHCHL_01285 2.34e-77 yokL3 - - J - - - Acetyltransferase (GNAT) domain
DEFGHCHL_01286 5.68e-240 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DEFGHCHL_01287 5.92e-33 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
DEFGHCHL_01288 3.73e-265 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
DEFGHCHL_01290 1.19e-79 - - - K - - - helix_turn_helix, arabinose operon control protein
DEFGHCHL_01291 2.74e-69 - - - S - - - Membrane
DEFGHCHL_01292 8.6e-211 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
DEFGHCHL_01293 1.24e-120 B4168_4126 - - L ko:K07493 - ko00000 Transposase
DEFGHCHL_01294 1.59e-15 - - - S - - - Protein of unknown function (DUF3021)
DEFGHCHL_01295 3.13e-35 - - - K ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
DEFGHCHL_01296 4.18e-75 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
DEFGHCHL_01297 1.2e-94 cylA - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
DEFGHCHL_01298 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
DEFGHCHL_01299 1.35e-121 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DEFGHCHL_01300 2.44e-104 - - - - - - - -
DEFGHCHL_01301 5.49e-65 - - - L - - - Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DEFGHCHL_01302 0.0 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
DEFGHCHL_01303 8.78e-94 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
DEFGHCHL_01304 2.31e-167 - - - L - - - Belongs to the 'phage' integrase family
DEFGHCHL_01305 1.98e-44 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
DEFGHCHL_01306 4.29e-260 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
DEFGHCHL_01307 4.62e-116 - - - L ko:K07484 - ko00000 Transposase IS66 family
DEFGHCHL_01308 3.01e-39 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
DEFGHCHL_01309 3.22e-62 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain protein
DEFGHCHL_01310 4.25e-58 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
DEFGHCHL_01312 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DEFGHCHL_01313 3.45e-36 ykuJ - - S - - - Protein of unknown function (DUF1797)
DEFGHCHL_01314 2.51e-165 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DEFGHCHL_01315 1.84e-163 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
DEFGHCHL_01316 2.56e-203 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
DEFGHCHL_01317 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DEFGHCHL_01318 5.69e-49 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
DEFGHCHL_01319 1.5e-22 - - - - - - - -
DEFGHCHL_01320 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
DEFGHCHL_01321 1.24e-31 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
DEFGHCHL_01322 6.64e-131 - - - G - - - MucBP domain
DEFGHCHL_01323 1.55e-61 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
DEFGHCHL_01324 3.64e-303 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
DEFGHCHL_01325 4.92e-252 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
DEFGHCHL_01326 1.26e-207 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
DEFGHCHL_01327 1.07e-225 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DEFGHCHL_01328 3.21e-139 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
DEFGHCHL_01329 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
DEFGHCHL_01330 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 -beta-galactosidase
DEFGHCHL_01331 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DEFGHCHL_01332 1.97e-146 tagH 3.6.3.40 - GM ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
DEFGHCHL_01333 3.8e-201 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
DEFGHCHL_01334 8.16e-135 yueF - - S - - - AI-2E family transporter
DEFGHCHL_01335 9.74e-126 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
DEFGHCHL_01336 1.81e-241 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DEFGHCHL_01337 2.25e-79 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
DEFGHCHL_01339 3.84e-31 - - - S - - - Cytochrome B5
DEFGHCHL_01340 2.05e-53 ytlR - - I - - - Diacylglycerol kinase catalytic domain
DEFGHCHL_01341 2.05e-75 - - - - - - - -
DEFGHCHL_01342 3.12e-57 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
DEFGHCHL_01343 4.01e-197 yngD - - S ko:K07097 - ko00000 DHHA1 domain
DEFGHCHL_01344 9.14e-117 yunF - - F - - - Protein of unknown function DUF72
DEFGHCHL_01345 5e-64 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
DEFGHCHL_01347 7.6e-182 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DEFGHCHL_01348 1.5e-40 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DEFGHCHL_01349 1.32e-282 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
DEFGHCHL_01350 2.32e-224 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DEFGHCHL_01351 2.99e-81 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
DEFGHCHL_01352 7.55e-78 yciB - - M - - - ErfK YbiS YcfS YnhG
DEFGHCHL_01354 2.54e-105 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
DEFGHCHL_01355 2.89e-229 pbuG - - S ko:K06901 - ko00000,ko02000 permease
DEFGHCHL_01357 3.5e-99 - - - S - - - Cell surface protein
DEFGHCHL_01359 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
DEFGHCHL_01360 1.29e-78 - - - - - - - -
DEFGHCHL_01361 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
DEFGHCHL_01362 1.93e-240 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DEFGHCHL_01363 4.42e-253 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DEFGHCHL_01365 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DEFGHCHL_01366 1.75e-57 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
DEFGHCHL_01367 1.8e-32 ywiB - - S - - - Domain of unknown function (DUF1934)
DEFGHCHL_01368 4.97e-110 - - - F - - - glutamine amidotransferase
DEFGHCHL_01369 1.15e-259 ywfO - - S ko:K06885 - ko00000 HD domain protein
DEFGHCHL_01370 7.11e-111 - - - S - - - hydrolase
DEFGHCHL_01371 3.72e-133 - - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
DEFGHCHL_01372 7.3e-79 - - - - - - - -
DEFGHCHL_01374 6.89e-26 recD2_2 3.1.11.5 - L ko:K01144 - ko00000,ko01000 PIF1-like helicase
DEFGHCHL_01376 1.68e-61 spoVK - - O - - - ATPase family associated with various cellular activities (AAA)
DEFGHCHL_01378 6.71e-110 - - - S - - - overlaps another CDS with the same product name
DEFGHCHL_01379 1.59e-156 yibE - - S - - - overlaps another CDS with the same product name
DEFGHCHL_01380 4.69e-122 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DEFGHCHL_01381 3.1e-36 ytkL - - S - - - Belongs to the UPF0173 family
DEFGHCHL_01382 2.27e-30 bCE_4747 - - S - - - Beta-lactamase superfamily domain
DEFGHCHL_01383 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
DEFGHCHL_01384 9.74e-100 - - - F - - - Phosphorylase superfamily
DEFGHCHL_01385 2.13e-32 - - - - - - - -
DEFGHCHL_01386 1.94e-139 dkgB - - S - - - Aldo/keto reductase family
DEFGHCHL_01387 1.76e-24 rimL 1.1.1.25 - J ko:K00014,ko:K03817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko03009 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEFGHCHL_01388 2.25e-216 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DEFGHCHL_01389 7.9e-257 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DEFGHCHL_01390 4.84e-72 - - - EGP - - - Transmembrane secretion effector
DEFGHCHL_01391 7.37e-175 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
DEFGHCHL_01392 2.08e-67 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
DEFGHCHL_01393 6.82e-235 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DEFGHCHL_01394 9.41e-142 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
DEFGHCHL_01395 4.48e-158 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEFGHCHL_01396 3.5e-190 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
DEFGHCHL_01397 1.6e-248 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
DEFGHCHL_01398 2.24e-252 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
DEFGHCHL_01400 2.59e-194 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
DEFGHCHL_01401 5.09e-148 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DEFGHCHL_01402 1.03e-61 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
DEFGHCHL_01403 1.36e-171 arcT - - E - - - Cys/Met metabolism PLP-dependent enzyme
DEFGHCHL_01404 7.69e-115 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
DEFGHCHL_01405 1.9e-31 veg - - S - - - Biofilm formation stimulator VEG
DEFGHCHL_01406 1.61e-170 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DEFGHCHL_01407 5.68e-111 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DEFGHCHL_01408 3.62e-133 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
DEFGHCHL_01409 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEFGHCHL_01410 1.85e-161 - - - - - - - -
DEFGHCHL_01411 2.66e-191 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
DEFGHCHL_01412 1.49e-54 - - - ET - - - Bacterial extracellular solute-binding proteins, family 3
DEFGHCHL_01413 2.7e-40 - - - K - - - Bacterial regulatory proteins, tetR family
DEFGHCHL_01414 5.19e-130 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
DEFGHCHL_01415 1.58e-105 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
DEFGHCHL_01416 2.78e-129 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
DEFGHCHL_01417 2.82e-217 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
DEFGHCHL_01418 9.15e-45 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DEFGHCHL_01419 1.22e-90 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DEFGHCHL_01420 0.0 - - - L - - - DNA helicase
DEFGHCHL_01422 1.77e-155 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
DEFGHCHL_01423 3.17e-94 lemA - - S ko:K03744 - ko00000 LemA family
DEFGHCHL_01424 1.2e-67 ymdB - - L - - - phosphatase homologous to the C-terminal domain of histone macroH2A1
DEFGHCHL_01425 5.29e-59 yyaT - - K ko:K02348 - ko00000 protein acetylation
DEFGHCHL_01426 1.29e-11 - - - - - - - -
DEFGHCHL_01427 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
DEFGHCHL_01428 3.61e-213 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
DEFGHCHL_01429 1.24e-45 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
DEFGHCHL_01430 4.44e-44 - - - K - - - Bacterial regulatory proteins, tetR family
DEFGHCHL_01431 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DEFGHCHL_01432 4.12e-64 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DEFGHCHL_01433 1.22e-199 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DEFGHCHL_01434 1.18e-149 - - - G - - - Transporter, major facilitator family protein
DEFGHCHL_01435 1.78e-26 - - - G - - - Transporter, major facilitator family protein
DEFGHCHL_01436 5.88e-113 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
DEFGHCHL_01437 5.29e-191 hpk31 - - T - - - Histidine kinase
DEFGHCHL_01438 1.21e-145 vanR - - K - - - response regulator
DEFGHCHL_01439 1.11e-105 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
DEFGHCHL_01440 3.83e-116 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
DEFGHCHL_01441 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DEFGHCHL_01442 1.39e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DEFGHCHL_01443 2.95e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DEFGHCHL_01444 2.24e-29 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
DEFGHCHL_01445 2.69e-07 - - - K ko:K03826 - ko00000,ko01000 Psort location Cytoplasmic, score 8.87
DEFGHCHL_01446 1.23e-21 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
DEFGHCHL_01447 1.83e-10 - - - K ko:K03826 - ko00000,ko01000 Acetyltransferase, GNAT family
DEFGHCHL_01449 1.73e-49 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DEFGHCHL_01450 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
DEFGHCHL_01451 1.22e-66 - - - C - - - Oxidoreductase NAD-binding domain
DEFGHCHL_01452 9.94e-77 - - - L ko:K07491 - ko00000 Transposase IS200 like
DEFGHCHL_01453 2.85e-197 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
DEFGHCHL_01454 8.45e-120 - - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
DEFGHCHL_01455 8.3e-160 - - - K ko:K21562 - ko00000,ko03000 helix_turn_helix, cAMP Regulatory protein
DEFGHCHL_01456 2.58e-53 - - - L ko:K07497 - ko00000 hmm pf00665
DEFGHCHL_01457 6.46e-27 tnp - - - ko:K07498 - ko00000 -
DEFGHCHL_01458 1.32e-33 - - - L ko:K07498 - ko00000 Transposase
DEFGHCHL_01459 3.43e-45 - - - P - - - Heavy-metal-associated domain
DEFGHCHL_01460 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
DEFGHCHL_01461 1.2e-28 - - - L ko:K07483 - ko00000 PFAM transposase IS3 IS911 family protein
DEFGHCHL_01462 6.56e-52 - - - L ko:K07497 - ko00000 Integrase core domain
DEFGHCHL_01463 1.71e-43 - - - L ko:K07497 - ko00000 Integrase core domain
DEFGHCHL_01464 2.01e-60 - - - EGP - - - Major Facilitator Superfamily
DEFGHCHL_01465 2.41e-43 - - - EGP - - - Major Facilitator Superfamily
DEFGHCHL_01466 7.05e-123 - - - EGP - - - Major Facilitator Superfamily
DEFGHCHL_01467 1.06e-88 - - - K - - - Transcriptional regulator, LysR family
DEFGHCHL_01468 6.08e-176 - - - G - - - Xylose isomerase-like TIM barrel
DEFGHCHL_01469 9.99e-148 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
DEFGHCHL_01470 1.7e-270 - 1.3.5.1, 1.3.5.4 - C ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 ko00000,ko00001,ko00002,ko01000 FAD binding domain
DEFGHCHL_01471 2.43e-174 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DEFGHCHL_01472 4.79e-89 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
DEFGHCHL_01473 6.28e-181 xerS - - L ko:K04763 - ko00000,ko03036 Phage integrase family
DEFGHCHL_01477 2.67e-112 bsh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
DEFGHCHL_01478 3.03e-88 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
DEFGHCHL_01479 3.36e-97 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
DEFGHCHL_01480 1.22e-72 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DEFGHCHL_01481 1.94e-67 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
DEFGHCHL_01482 6.88e-100 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
DEFGHCHL_01484 1.7e-12 yhaI - - S - - - Protein of unknown function (DUF805)
DEFGHCHL_01485 1.38e-06 lanR - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
DEFGHCHL_01486 1.15e-126 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DEFGHCHL_01487 3.52e-100 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
DEFGHCHL_01488 8.92e-35 - - - - - - - -
DEFGHCHL_01489 3.76e-18 - - - - - - - -
DEFGHCHL_01490 7.51e-142 rssA - - S - - - Phospholipase, patatin family
DEFGHCHL_01491 5.49e-175 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DEFGHCHL_01492 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
DEFGHCHL_01493 1.77e-63 - - - S - - - VIT family
DEFGHCHL_01494 2.63e-303 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
DEFGHCHL_01495 1.15e-53 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
DEFGHCHL_01496 2.09e-184 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DEFGHCHL_01497 7.04e-178 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
DEFGHCHL_01498 2.59e-148 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
DEFGHCHL_01499 2.22e-281 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
DEFGHCHL_01501 3.32e-26 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
DEFGHCHL_01502 3.04e-36 - - - K - - - Helix-turn-helix XRE-family like proteins
DEFGHCHL_01504 7.58e-43 - - - S - - - ABC-2 family transporter protein
DEFGHCHL_01505 2.14e-92 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
DEFGHCHL_01506 5.88e-130 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
DEFGHCHL_01507 6.55e-113 spaR - - KT ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
DEFGHCHL_01508 3.76e-91 spaC1 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C-like protein
DEFGHCHL_01509 1.3e-228 nisT - - V ko:K06147,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ATPases associated with a variety of cellular activities
DEFGHCHL_01510 2.07e-255 bsaB - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
DEFGHCHL_01512 3.83e-173 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
DEFGHCHL_01513 3.14e-147 ddh 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEFGHCHL_01514 1.26e-79 mipB 2.2.1.2 - H ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
DEFGHCHL_01515 2.21e-47 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
DEFGHCHL_01516 1.05e-172 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
DEFGHCHL_01517 1.93e-106 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
DEFGHCHL_01518 7.01e-57 srlM1 - - K - - - Glucitol operon activator protein (GutM)
DEFGHCHL_01519 7.16e-94 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
DEFGHCHL_01520 3.37e-141 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
DEFGHCHL_01521 6.35e-206 ytbD - - EGP ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
DEFGHCHL_01522 6.42e-125 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
DEFGHCHL_01523 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
DEFGHCHL_01524 2.7e-188 - - - M - - - YSIRK type signal peptide
DEFGHCHL_01525 5.16e-11 - - - M - - - domain protein
DEFGHCHL_01526 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 phosphatase activity
DEFGHCHL_01527 8.56e-90 - - - L - - - Phage integrase, N-terminal SAM-like domain
DEFGHCHL_01530 5.15e-114 - - - S - - - Haloacid dehalogenase-like hydrolase
DEFGHCHL_01531 5.5e-18 - - - - - - - -
DEFGHCHL_01533 3.3e-236 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
DEFGHCHL_01534 2.66e-102 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
DEFGHCHL_01535 2.27e-86 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
DEFGHCHL_01536 5.79e-54 yitW - - S - - - Iron-sulfur cluster assembly protein
DEFGHCHL_01537 5.41e-144 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
DEFGHCHL_01538 7.41e-81 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
DEFGHCHL_01539 1.02e-259 - - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEFGHCHL_01540 1.63e-193 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
DEFGHCHL_01541 1.51e-81 - - - G - - - Xylose isomerase domain protein TIM barrel
DEFGHCHL_01542 3.08e-70 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
DEFGHCHL_01543 2.9e-114 nanK - - GK - - - ROK family
DEFGHCHL_01544 4.39e-162 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
DEFGHCHL_01545 5.09e-118 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DEFGHCHL_01546 2.33e-95 - - - K - - - Helix-turn-helix domain, rpiR family
DEFGHCHL_01547 3.9e-38 yphA - - GM - - - NAD dependent epimerase/dehydratase family
DEFGHCHL_01548 4.36e-271 potE - - E - - - Amino Acid
DEFGHCHL_01549 1.16e-08 - - - - - - - -
DEFGHCHL_01550 5.44e-43 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DEFGHCHL_01551 3.32e-288 fusA1 - - J - - - elongation factor G
DEFGHCHL_01552 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DEFGHCHL_01553 1.38e-113 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DEFGHCHL_01554 8.88e-216 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
DEFGHCHL_01555 8.33e-151 - 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Alcohol dehydrogenase GroES-like domain
DEFGHCHL_01556 1.46e-233 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
DEFGHCHL_01557 1.36e-47 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
DEFGHCHL_01558 2.62e-52 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DEFGHCHL_01559 9.75e-78 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
DEFGHCHL_01560 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
DEFGHCHL_01561 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
DEFGHCHL_01562 2.4e-214 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DEFGHCHL_01563 4.39e-165 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DEFGHCHL_01564 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEFGHCHL_01565 2.49e-100 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
DEFGHCHL_01566 9.26e-119 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DEFGHCHL_01567 1.23e-62 yabR - - J ko:K07571 - ko00000 RNA binding
DEFGHCHL_01568 1.49e-28 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
DEFGHCHL_01569 1.1e-42 yabO - - J - - - S4 domain protein
DEFGHCHL_01570 6.6e-173 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
DEFGHCHL_01571 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DEFGHCHL_01572 3.56e-96 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DEFGHCHL_01573 8.16e-202 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
DEFGHCHL_01574 2.2e-110 - - - S - - - (CBS) domain
DEFGHCHL_01575 1.27e-179 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DEFGHCHL_01576 4.09e-261 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DEFGHCHL_01577 1.43e-68 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
DEFGHCHL_01578 8.18e-73 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
DEFGHCHL_01579 6.85e-130 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
DEFGHCHL_01580 1.25e-143 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
DEFGHCHL_01581 1.92e-60 - - - M - - - LysM domain protein
DEFGHCHL_01582 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
DEFGHCHL_01583 6.4e-111 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DEFGHCHL_01584 8.1e-44 - - - K - - - transcriptional regulator (TetR family)
DEFGHCHL_01585 9.3e-140 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
DEFGHCHL_01586 9.44e-113 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DEFGHCHL_01587 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
DEFGHCHL_01588 9.85e-308 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
DEFGHCHL_01590 2.29e-79 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
DEFGHCHL_01591 1.04e-99 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DEFGHCHL_01592 5.11e-159 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DEFGHCHL_01593 3.1e-138 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DEFGHCHL_01594 8.76e-140 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DEFGHCHL_01595 2.27e-127 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DEFGHCHL_01596 4.47e-71 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
DEFGHCHL_01597 1.93e-198 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DEFGHCHL_01598 1.24e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DEFGHCHL_01599 7.34e-74 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DEFGHCHL_01600 1.72e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
DEFGHCHL_01601 7.16e-47 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DEFGHCHL_01602 8.94e-143 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DEFGHCHL_01603 1.05e-266 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DEFGHCHL_01604 1.13e-88 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
DEFGHCHL_01605 1.65e-31 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
DEFGHCHL_01606 2.08e-106 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DEFGHCHL_01607 2.4e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DEFGHCHL_01608 4.99e-113 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DEFGHCHL_01609 5.17e-86 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DEFGHCHL_01610 4.1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DEFGHCHL_01611 1.61e-119 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DEFGHCHL_01612 3.84e-62 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DEFGHCHL_01613 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DEFGHCHL_01614 5.05e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DEFGHCHL_01615 2.63e-32 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
DEFGHCHL_01616 8.95e-95 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DEFGHCHL_01617 1.62e-149 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DEFGHCHL_01618 9.15e-72 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DEFGHCHL_01619 5.93e-60 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DEFGHCHL_01620 9.24e-183 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DEFGHCHL_01621 1.34e-52 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DEFGHCHL_01622 6.55e-130 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
DEFGHCHL_01623 2.82e-140 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DEFGHCHL_01624 3.24e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
DEFGHCHL_01625 7.36e-219 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DEFGHCHL_01626 6.12e-100 - - - K - - - rpiR family
DEFGHCHL_01627 1.15e-68 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
DEFGHCHL_01628 5.86e-188 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
DEFGHCHL_01629 2.79e-14 - - - K - - - Acetyltransferase (GNAT) domain
DEFGHCHL_01630 1e-240 steT - - E ko:K03294 - ko00000 amino acid
DEFGHCHL_01631 1.88e-104 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
DEFGHCHL_01632 4.89e-111 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
DEFGHCHL_01633 2.79e-125 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
DEFGHCHL_01634 7.01e-132 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
DEFGHCHL_01635 1.32e-17 - - - - - - - -
DEFGHCHL_01636 9.05e-123 - - - - - - - -
DEFGHCHL_01637 2.09e-16 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
DEFGHCHL_01638 2.87e-68 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
DEFGHCHL_01639 1.24e-268 yhdG - - E ko:K03294 - ko00000 Amino Acid
DEFGHCHL_01640 5.89e-316 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DEFGHCHL_01641 0.0 - - - L - - - Helicase C-terminal domain protein
DEFGHCHL_01642 1.77e-101 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
DEFGHCHL_01643 6.84e-232 yhdP - - S - - - Transporter associated domain
DEFGHCHL_01644 1.57e-32 - - - - - - - -
DEFGHCHL_01645 5.82e-97 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
DEFGHCHL_01646 1.13e-162 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
DEFGHCHL_01647 1.13e-125 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
DEFGHCHL_01648 1.28e-90 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEFGHCHL_01649 6.88e-200 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
DEFGHCHL_01650 2.8e-174 - - - V - - - MatE
DEFGHCHL_01651 6.55e-58 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DEFGHCHL_01652 5.52e-111 - - - S - - - Alpha beta hydrolase
DEFGHCHL_01653 5.27e-122 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DEFGHCHL_01654 5.23e-219 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
DEFGHCHL_01655 4.34e-138 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
DEFGHCHL_01656 9.04e-131 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
DEFGHCHL_01657 8.54e-45 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
DEFGHCHL_01658 1.09e-68 ccl - - S - - - QueT transporter
DEFGHCHL_01660 5.34e-83 - - - S - - - Uncharacterised protein, DegV family COG1307
DEFGHCHL_01661 1.18e-28 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DEFGHCHL_01662 3.11e-28 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DEFGHCHL_01663 7.86e-46 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
DEFGHCHL_01664 2.09e-110 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
DEFGHCHL_01665 3.06e-157 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
DEFGHCHL_01666 3.42e-65 - - - S - - - Threonine/Serine exporter, ThrE
DEFGHCHL_01667 1.11e-102 - - - S - - - Putative threonine/serine exporter
DEFGHCHL_01668 1.37e-37 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
DEFGHCHL_01669 3.57e-115 mntR - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
DEFGHCHL_01670 5.83e-117 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
DEFGHCHL_01671 2.39e-27 - - - - - - - -
DEFGHCHL_01672 9.17e-75 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatase
DEFGHCHL_01673 4.48e-24 - - - - - - - -
DEFGHCHL_01674 5.6e-80 - - - I - - - alpha/beta hydrolase fold
DEFGHCHL_01675 2.61e-52 - - - S - - - branched-chain amino acid
DEFGHCHL_01676 1.78e-132 - - - E - - - AzlC protein
DEFGHCHL_01677 1.28e-24 - - - - - - - -
DEFGHCHL_01678 6.22e-164 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
DEFGHCHL_01679 7.9e-135 yhgE - - V ko:K01421 - ko00000 domain protein
DEFGHCHL_01681 0.000248 - - - S - - - zinc-ribbon domain
DEFGHCHL_01684 1e-53 - - - S - - - virion core protein, lumpy skin disease virus
DEFGHCHL_01685 8.68e-159 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DEFGHCHL_01686 3.84e-218 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
DEFGHCHL_01687 2.26e-148 ydbI - - K - - - AI-2E family transporter
DEFGHCHL_01688 8.37e-76 - - - EG - - - EamA-like transporter family
DEFGHCHL_01689 4.55e-98 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
DEFGHCHL_01690 2.28e-146 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
DEFGHCHL_01691 2.78e-85 - 1.5.1.38 - S ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
DEFGHCHL_01692 3.82e-71 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
DEFGHCHL_01693 1.83e-230 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
DEFGHCHL_01694 1.9e-116 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
DEFGHCHL_01695 3.96e-92 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
DEFGHCHL_01696 2.58e-76 yceE - - S - - - haloacid dehalogenase-like hydrolase
DEFGHCHL_01697 7.18e-51 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
DEFGHCHL_01698 1.12e-41 - - - S - - - Domain of unknown function (DUF4811)
DEFGHCHL_01699 1.41e-246 ycnB - - U - - - Belongs to the major facilitator superfamily
DEFGHCHL_01700 2.49e-43 - - - K - - - MerR HTH family regulatory protein
DEFGHCHL_01701 1.29e-51 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DEFGHCHL_01702 1.22e-89 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
DEFGHCHL_01703 1.19e-147 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
DEFGHCHL_01704 1.46e-101 yfiK - - KT ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DEFGHCHL_01705 3.34e-122 baeS - - T - - - Histidine kinase
DEFGHCHL_01706 6.18e-101 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 sugar-binding domain protein
DEFGHCHL_01707 3.19e-192 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
DEFGHCHL_01708 1.69e-153 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
DEFGHCHL_01709 1.4e-188 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
DEFGHCHL_01710 1.61e-67 - - - S - - - Domain of unknown function (DUF956)
DEFGHCHL_01711 5.58e-93 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
DEFGHCHL_01712 2.89e-164 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DEFGHCHL_01713 8.6e-207 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEFGHCHL_01714 3.33e-97 ung2 - - L - - - Uracil-DNA glycosylase
DEFGHCHL_01715 3.61e-43 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
DEFGHCHL_01716 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
DEFGHCHL_01717 4.45e-136 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DEFGHCHL_01718 7.44e-51 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DEFGHCHL_01719 3e-38 - - - S - - - CRISPR-associated protein (Cas_Csn2)
DEFGHCHL_01720 1.77e-50 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
DEFGHCHL_01721 2.01e-27 - - - S - - - Protein of unknown function (DUF1700)
DEFGHCHL_01722 5.5e-08 - - - S - - - Putative adhesin
DEFGHCHL_01723 8.46e-23 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
DEFGHCHL_01726 2.91e-296 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DEFGHCHL_01727 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
DEFGHCHL_01728 2.31e-130 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
DEFGHCHL_01729 1.28e-211 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
DEFGHCHL_01730 3.85e-153 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
DEFGHCHL_01731 3.11e-133 potC - - U ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
DEFGHCHL_01732 1.19e-201 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
DEFGHCHL_01733 7.9e-169 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
DEFGHCHL_01734 9.74e-147 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
DEFGHCHL_01735 5.74e-138 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DEFGHCHL_01736 3.36e-85 yciB - - M - - - ErfK YbiS YcfS YnhG
DEFGHCHL_01737 2.68e-69 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DEFGHCHL_01738 2.49e-285 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DEFGHCHL_01739 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DEFGHCHL_01740 2.22e-131 pgm3 - - G - - - phosphoglycerate mutase
DEFGHCHL_01741 2.05e-70 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
DEFGHCHL_01742 6.33e-62 - - - C - - - Flavodoxin
DEFGHCHL_01743 5.24e-79 yphH - - S - - - Cupin domain
DEFGHCHL_01744 1.78e-60 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
DEFGHCHL_01745 5.89e-177 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
DEFGHCHL_01746 4.23e-135 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
DEFGHCHL_01747 1.32e-188 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DEFGHCHL_01748 6.39e-120 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
DEFGHCHL_01749 1.85e-167 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
DEFGHCHL_01750 2.84e-107 - - - C - - - nitroreductase
DEFGHCHL_01751 5.05e-105 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
DEFGHCHL_01752 1.16e-136 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
DEFGHCHL_01753 1.5e-214 npr 1.11.1.1 - S ko:K05910 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
DEFGHCHL_01754 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
DEFGHCHL_01756 1.78e-191 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DEFGHCHL_01757 1.02e-73 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
DEFGHCHL_01758 3.63e-163 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
DEFGHCHL_01759 2.09e-40 - - - S - - - Protein of unknown function (DUF4256)
DEFGHCHL_01763 6.07e-223 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
DEFGHCHL_01764 7.47e-213 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
DEFGHCHL_01765 2.72e-230 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DEFGHCHL_01766 2.52e-290 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
DEFGHCHL_01767 2.72e-186 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
DEFGHCHL_01768 9.52e-72 - - - S - - - Protein of unknown function (DUF975)
DEFGHCHL_01769 4.91e-79 - - - E - - - GDSL-like Lipase/Acylhydrolase family
DEFGHCHL_01770 1.01e-16 - - - - - - - -
DEFGHCHL_01771 3.81e-37 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
DEFGHCHL_01772 2.79e-281 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
DEFGHCHL_01773 1.39e-111 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
DEFGHCHL_01774 4.7e-192 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
DEFGHCHL_01775 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
DEFGHCHL_01776 7.12e-77 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain protein
DEFGHCHL_01777 1.08e-156 - - - S - - - Bacteriophage abortive infection AbiH
DEFGHCHL_01780 1.55e-205 spoVK - - O - - - ATPase family associated with various cellular activities (AAA)
DEFGHCHL_01781 4.9e-67 - - - K - - - Cro/C1-type HTH DNA-binding domain
DEFGHCHL_01783 4.21e-82 - - - S - - - Acetyltransferase (GNAT) domain
DEFGHCHL_01784 8.83e-93 ywlG - - S - - - Belongs to the UPF0340 family
DEFGHCHL_01785 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
DEFGHCHL_01786 2.11e-122 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DEFGHCHL_01787 6e-76 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DEFGHCHL_01788 2.02e-221 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
DEFGHCHL_01789 4.82e-20 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
DEFGHCHL_01790 7.52e-302 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
DEFGHCHL_01791 4.81e-250 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
DEFGHCHL_01792 3.63e-267 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
DEFGHCHL_01793 1.34e-51 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
DEFGHCHL_01794 1.32e-204 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DEFGHCHL_01795 1.28e-76 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
DEFGHCHL_01796 1.7e-129 ypuA - - S - - - Protein of unknown function (DUF1002)
DEFGHCHL_01798 3.1e-130 - - - M - - - Rib/alpha-like repeat
DEFGHCHL_01799 3.11e-112 - - - M - - - Rib/alpha-like repeat
DEFGHCHL_01800 1.15e-27 - - - M - - - Rib/alpha-like repeat
DEFGHCHL_01801 1.76e-58 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
DEFGHCHL_01802 2.3e-78 usp2 - - T - - - Belongs to the universal stress protein A family
DEFGHCHL_01803 3.34e-52 - - - K - - - Bacterial regulatory proteins, tetR family
DEFGHCHL_01804 3.65e-74 napB - - K - - - transcriptional
DEFGHCHL_01805 3.21e-89 mleR - - K - - - LysR family
DEFGHCHL_01806 1.96e-312 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
DEFGHCHL_01807 1.24e-161 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
DEFGHCHL_01808 1.63e-81 - - - S - - - ECF transporter, substrate-specific component
DEFGHCHL_01809 3.17e-78 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
DEFGHCHL_01810 5.57e-96 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DEFGHCHL_01811 1.28e-253 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
DEFGHCHL_01812 7.98e-49 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
DEFGHCHL_01813 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
DEFGHCHL_01814 5.56e-124 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
DEFGHCHL_01815 2.54e-148 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DEFGHCHL_01816 6.89e-118 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
DEFGHCHL_01817 5.17e-228 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
DEFGHCHL_01819 1.96e-54 - - - - - - - -
DEFGHCHL_01820 9.28e-42 - - - K - - - GNAT family
DEFGHCHL_01821 4.59e-262 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
DEFGHCHL_01822 1.02e-277 gdhA 1.4.1.3, 1.4.1.4 - E ko:K00261,ko:K00262 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 ko00000,ko00001,ko00002,ko01000,ko04147 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
DEFGHCHL_01823 2.89e-43 - - - O - - - ADP-ribosylglycohydrolase
DEFGHCHL_01824 3.59e-273 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
DEFGHCHL_01825 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DEFGHCHL_01826 1.95e-208 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DEFGHCHL_01827 9.63e-158 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
DEFGHCHL_01828 1.82e-243 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
DEFGHCHL_01829 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DEFGHCHL_01830 1.14e-213 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
DEFGHCHL_01831 7.99e-33 - - - S - - - Domain of unknown function (DUF4828)
DEFGHCHL_01832 1.08e-160 mocA - - S - - - Oxidoreductase
DEFGHCHL_01833 9.82e-202 yfmL - - L - - - DEAD DEAH box helicase
DEFGHCHL_01836 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
DEFGHCHL_01837 4.67e-126 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
DEFGHCHL_01838 3.51e-270 - - - G ko:K16211 - ko00000,ko02000 Transporter, major facilitator family protein
DEFGHCHL_01839 7.71e-95 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
DEFGHCHL_01840 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
DEFGHCHL_01841 7.68e-109 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
DEFGHCHL_01842 1.4e-38 - - - S - - - Belongs to the HesB IscA family
DEFGHCHL_01843 1.38e-83 icaB - - G - - - Polysaccharide deacetylase
DEFGHCHL_01845 5e-67 - - - K - - - LysR substrate binding domain
DEFGHCHL_01846 1.66e-152 - - - S - - - Conserved hypothetical protein 698
DEFGHCHL_01847 2.06e-253 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
DEFGHCHL_01848 3.78e-138 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DEFGHCHL_01849 8.2e-65 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DEFGHCHL_01850 2.29e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
DEFGHCHL_01851 1.1e-257 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DEFGHCHL_01852 8.98e-202 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DEFGHCHL_01853 4.51e-27 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
DEFGHCHL_01854 1.38e-192 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DEFGHCHL_01855 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DEFGHCHL_01856 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DEFGHCHL_01857 7.37e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
DEFGHCHL_01858 6.48e-89 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DEFGHCHL_01859 3.82e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DEFGHCHL_01860 4.29e-140 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
DEFGHCHL_01861 9.4e-148 - - - S - - - Glycosyl transferase family 2
DEFGHCHL_01862 2.26e-81 - - - D - - - peptidase
DEFGHCHL_01863 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
DEFGHCHL_01864 1.3e-48 - - - S - - - Protein of unknown function (DUF1211)
DEFGHCHL_01866 5.27e-53 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DEFGHCHL_01867 1.08e-305 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
DEFGHCHL_01868 5.01e-22 yneR - - - - - - -
DEFGHCHL_01869 7.19e-290 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DEFGHCHL_01870 7.54e-284 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
DEFGHCHL_01871 3.32e-136 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
DEFGHCHL_01872 1.05e-191 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
DEFGHCHL_01873 1.12e-11 yobS - - K - - - Bacterial regulatory proteins, tetR family
DEFGHCHL_01874 8.94e-141 - - - U ko:K05340 - ko00000,ko02000 sugar transport
DEFGHCHL_01875 3.74e-212 - - - S - - - Putative threonine/serine exporter
DEFGHCHL_01876 6.27e-90 - - - J - - - Acetyltransferase (GNAT) domain
DEFGHCHL_01877 4.69e-121 yicL - - EG - - - EamA-like transporter family
DEFGHCHL_01878 7.89e-279 pepF - - E - - - Oligopeptidase F
DEFGHCHL_01879 2.04e-137 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
DEFGHCHL_01880 2.01e-224 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
DEFGHCHL_01881 4.63e-175 - 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
DEFGHCHL_01882 2.06e-80 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
DEFGHCHL_01883 2.51e-31 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
DEFGHCHL_01885 1.06e-216 - - - S - - - Putative peptidoglycan binding domain
DEFGHCHL_01886 4.68e-41 - - - K - - - Transcriptional regulator, MarR family
DEFGHCHL_01887 2.16e-269 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
DEFGHCHL_01888 1.11e-286 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
DEFGHCHL_01890 3.56e-106 - - - S ko:K19175 - ko00000,ko02048 Domain of unknown function DUF87
DEFGHCHL_01892 5.63e-108 yxeH - - S - - - hydrolase
DEFGHCHL_01893 2.43e-151 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
DEFGHCHL_01894 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DEFGHCHL_01895 7.57e-126 yycH - - S - - - YycH protein
DEFGHCHL_01896 3.35e-100 yycI - - S - - - YycH protein
DEFGHCHL_01897 4.78e-41 - - - S - - - YjbR
DEFGHCHL_01898 1.46e-147 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
DEFGHCHL_01899 2.33e-187 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
DEFGHCHL_01900 7.88e-94 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DEFGHCHL_01901 2.65e-52 - - - GM - - - NAD(P)H-binding
DEFGHCHL_01902 2.59e-34 - - - K - - - MarR family transcriptional regulator
DEFGHCHL_01903 5.45e-112 - - - GM - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
DEFGHCHL_01904 7.15e-58 - - - S - - - PD-(D/E)XK nuclease family transposase
DEFGHCHL_01905 5.59e-262 glpT - - G ko:K02445 - ko00000,ko02000 glycerol-3-phosphate transporter

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)