ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HMIFHPHL_00001 6.01e-107 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HMIFHPHL_00002 3.28e-197 cylA - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HMIFHPHL_00003 1.1e-177 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
HMIFHPHL_00005 1.01e-117 ydhK - - M - - - Protein of unknown function (DUF1541)
HMIFHPHL_00006 1.08e-245 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
HMIFHPHL_00007 6.18e-283 - - - S - - - Calcineurin-like phosphoesterase
HMIFHPHL_00008 1.74e-69 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HMIFHPHL_00009 1.05e-33 - - - S - - - Fic/DOC family
HMIFHPHL_00010 1.05e-31 - - - S - - - Bacteriophage abortive infection AbiH
HMIFHPHL_00011 4.09e-213 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HMIFHPHL_00012 5.8e-46 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HMIFHPHL_00013 5.81e-88 - - - L - - - Transposase
HMIFHPHL_00014 2.47e-174 mob - - D - - - Plasmid recombination enzyme
HMIFHPHL_00017 9.73e-208 - - - L - - - Replication protein
HMIFHPHL_00018 9.07e-107 - - - EGP - - - Major Facilitator
HMIFHPHL_00019 3.63e-247 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
HMIFHPHL_00020 4.27e-308 - - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HMIFHPHL_00021 2.97e-21 - - - S - - - Transglycosylase associated protein
HMIFHPHL_00022 4.68e-19 - - - S - - - Domain of unknown function (DUF4355)
HMIFHPHL_00023 6.24e-83 - - - S - - - Domain of unknown function (DUF4355)
HMIFHPHL_00024 8.26e-33 gpG - - - - - - -
HMIFHPHL_00025 0.0 cidC 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HMIFHPHL_00026 1.52e-64 - - - L - - - Transposase and inactivated derivatives, IS30 family
HMIFHPHL_00027 5.46e-84 - - - M - - - ErfK YbiS YcfS YnhG
HMIFHPHL_00028 3.92e-45 - - - - - - - -
HMIFHPHL_00030 1.76e-90 - - - K - - - Helix-turn-helix XRE-family like proteins
HMIFHPHL_00032 1.31e-139 - - - L - - - Integrase
HMIFHPHL_00033 4.17e-55 - - - K - - - prlF antitoxin for toxin YhaV_toxin
HMIFHPHL_00034 1.2e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
HMIFHPHL_00035 2.77e-77 - - - - - - - -
HMIFHPHL_00036 2.54e-42 cspA - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HMIFHPHL_00037 5.09e-55 - - - - - - - -
HMIFHPHL_00038 7.39e-21 - - - - - - - -
HMIFHPHL_00039 1.87e-139 - - - L - - - Integrase
HMIFHPHL_00040 1.11e-59 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
HMIFHPHL_00041 5.03e-75 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
HMIFHPHL_00042 1.44e-114 - - - S ko:K07090 - ko00000 membrane transporter protein
HMIFHPHL_00043 2.21e-117 ung2 - - L - - - Uracil-DNA glycosylase
HMIFHPHL_00044 6.67e-157 pnb - - C - - - nitroreductase
HMIFHPHL_00045 4.95e-86 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
HMIFHPHL_00046 2.23e-150 - - - S - - - Elongation factor G-binding protein, N-terminal
HMIFHPHL_00047 0.0 - - - C - - - FMN_bind
HMIFHPHL_00048 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HMIFHPHL_00049 1.39e-202 - - - K - - - LysR family
HMIFHPHL_00050 5.88e-94 - - - C - - - FMN binding
HMIFHPHL_00051 4.48e-98 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMIFHPHL_00052 4.06e-211 - - - S - - - KR domain
HMIFHPHL_00053 9.51e-203 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
HMIFHPHL_00054 5.07e-157 ydgI - - C - - - Nitroreductase family
HMIFHPHL_00055 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
HMIFHPHL_00056 1.56e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HMIFHPHL_00057 2.66e-249 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HMIFHPHL_00058 0.0 - - - S - - - Putative threonine/serine exporter
HMIFHPHL_00059 6.86e-175 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HMIFHPHL_00060 0.0 hpaH 1.14.14.8, 1.14.14.9 - Q ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 ko00000,ko00001,ko01000 4-hydroxyphenylacetate
HMIFHPHL_00061 1.65e-106 - - - S - - - ASCH
HMIFHPHL_00062 3.06e-165 - - - F - - - glutamine amidotransferase
HMIFHPHL_00063 1.67e-220 - - - K - - - WYL domain
HMIFHPHL_00064 1.63e-152 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HMIFHPHL_00065 0.0 fusA1 - - J - - - elongation factor G
HMIFHPHL_00066 1.15e-163 - - - S - - - Protein of unknown function
HMIFHPHL_00067 1.74e-194 - - - EG - - - EamA-like transporter family
HMIFHPHL_00068 3.5e-117 yfbM - - K - - - FR47-like protein
HMIFHPHL_00069 5.46e-149 - - - S - - - DJ-1/PfpI family
HMIFHPHL_00070 2.93e-235 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
HMIFHPHL_00071 7.81e-67 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HMIFHPHL_00072 1.15e-299 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
HMIFHPHL_00073 9.01e-215 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HMIFHPHL_00074 9.06e-180 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HMIFHPHL_00075 2.38e-99 - - - - - - - -
HMIFHPHL_00076 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HMIFHPHL_00077 2.4e-180 - - - - - - - -
HMIFHPHL_00078 4.07e-05 - - - - - - - -
HMIFHPHL_00079 5.9e-186 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HMIFHPHL_00080 1.67e-54 - - - - - - - -
HMIFHPHL_00081 4.29e-166 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HMIFHPHL_00082 9.79e-192 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HMIFHPHL_00083 1.84e-235 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
HMIFHPHL_00084 1.39e-156 rcfB - - K - - - Crp-like helix-turn-helix domain
HMIFHPHL_00085 7.9e-306 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
HMIFHPHL_00086 7.58e-162 larB - - S ko:K06898 - ko00000 AIR carboxylase
HMIFHPHL_00087 3.08e-175 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HMIFHPHL_00088 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HMIFHPHL_00089 6.38e-194 larE - - S ko:K06864 - ko00000 NAD synthase
HMIFHPHL_00090 2.89e-226 - - - C - - - Zinc-binding dehydrogenase
HMIFHPHL_00092 1.87e-175 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HMIFHPHL_00093 7.44e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HMIFHPHL_00094 3.97e-145 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HMIFHPHL_00095 4.15e-261 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HMIFHPHL_00096 2.39e-174 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HMIFHPHL_00097 0.0 - - - L - - - HIRAN domain
HMIFHPHL_00098 3.55e-109 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HMIFHPHL_00099 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
HMIFHPHL_00100 7.06e-157 - - - - - - - -
HMIFHPHL_00101 2.94e-191 - - - I - - - Alpha/beta hydrolase family
HMIFHPHL_00102 0.0 pacL1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HMIFHPHL_00103 2.92e-38 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
HMIFHPHL_00104 5.13e-144 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
HMIFHPHL_00105 1.27e-98 - - - K - - - Transcriptional regulator
HMIFHPHL_00106 2.31e-95 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HMIFHPHL_00107 2.14e-39 - - - S - - - Protein of unknown function (DUF3021)
HMIFHPHL_00108 7.39e-87 - - - K - - - LytTr DNA-binding domain
HMIFHPHL_00109 1.8e-288 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HMIFHPHL_00110 2.21e-65 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HMIFHPHL_00111 2.79e-274 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
HMIFHPHL_00113 1.34e-198 morA - - S - - - reductase
HMIFHPHL_00114 8.21e-213 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo keto reductase
HMIFHPHL_00115 7.84e-106 - - - F - - - Nucleoside 2-deoxyribosyltransferase like
HMIFHPHL_00116 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HMIFHPHL_00117 1.1e-129 - - - - - - - -
HMIFHPHL_00118 0.0 - - - - - - - -
HMIFHPHL_00119 6.22e-266 - - - C - - - Oxidoreductase
HMIFHPHL_00120 7.71e-192 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
HMIFHPHL_00121 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_00122 2.57e-128 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
HMIFHPHL_00124 6.21e-167 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HMIFHPHL_00125 4.14e-72 - - - K - - - Transcriptional regulator PadR-like family
HMIFHPHL_00126 2.12e-180 - - - - - - - -
HMIFHPHL_00127 1.54e-185 - - - - - - - -
HMIFHPHL_00128 1.95e-114 - - - - - - - -
HMIFHPHL_00129 8.33e-184 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
HMIFHPHL_00130 7.04e-217 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HMIFHPHL_00131 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
HMIFHPHL_00132 8.03e-151 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
HMIFHPHL_00133 0.0 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
HMIFHPHL_00134 2.04e-99 - - - T - - - ECF transporter, substrate-specific component
HMIFHPHL_00136 1.85e-121 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
HMIFHPHL_00137 2.35e-243 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
HMIFHPHL_00138 3.88e-239 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
HMIFHPHL_00139 7.88e-131 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
HMIFHPHL_00140 6.76e-75 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
HMIFHPHL_00141 4e-172 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HMIFHPHL_00142 2.65e-245 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HMIFHPHL_00143 1.83e-231 yvdE - - K - - - helix_turn _helix lactose operon repressor
HMIFHPHL_00144 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
HMIFHPHL_00145 9.45e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HMIFHPHL_00146 3.74e-302 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMIFHPHL_00147 2.83e-206 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HMIFHPHL_00148 1.01e-190 malA - - S - - - maltodextrose utilization protein MalA
HMIFHPHL_00149 0.0 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
HMIFHPHL_00150 3.47e-267 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HMIFHPHL_00151 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HMIFHPHL_00152 0.0 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
HMIFHPHL_00153 2.01e-206 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
HMIFHPHL_00154 1.17e-60 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
HMIFHPHL_00155 1.08e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HMIFHPHL_00156 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HMIFHPHL_00157 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HMIFHPHL_00158 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HMIFHPHL_00159 2.4e-230 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
HMIFHPHL_00160 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HMIFHPHL_00161 9.92e-212 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
HMIFHPHL_00162 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HMIFHPHL_00163 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HMIFHPHL_00164 5.99e-213 mleR - - K - - - LysR substrate binding domain
HMIFHPHL_00165 0.0 - - - M - - - domain protein
HMIFHPHL_00167 1.03e-201 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HMIFHPHL_00168 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HMIFHPHL_00169 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HMIFHPHL_00170 9.25e-103 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HMIFHPHL_00171 1.45e-278 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMIFHPHL_00172 1.24e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HMIFHPHL_00173 2.73e-147 pgm1 - - G - - - phosphoglycerate mutase
HMIFHPHL_00174 1.01e-228 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
HMIFHPHL_00175 6.33e-46 - - - - - - - -
HMIFHPHL_00176 1.15e-79 - - - S - - - Domain of unknown function (DU1801)
HMIFHPHL_00177 1.53e-208 fbpA - - K - - - Domain of unknown function (DUF814)
HMIFHPHL_00178 7.45e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMIFHPHL_00179 3.81e-18 - - - - - - - -
HMIFHPHL_00180 3.18e-77 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMIFHPHL_00181 5.66e-74 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMIFHPHL_00182 0.0 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
HMIFHPHL_00183 2.13e-150 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
HMIFHPHL_00184 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HMIFHPHL_00185 1.43e-131 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
HMIFHPHL_00186 6.07e-117 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
HMIFHPHL_00187 1.25e-200 dkgB - - S - - - reductase
HMIFHPHL_00188 1.05e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMIFHPHL_00189 7.81e-88 - - - - - - - -
HMIFHPHL_00190 9.05e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMIFHPHL_00191 1.56e-221 - - - P - - - Major Facilitator Superfamily
HMIFHPHL_00192 5.55e-283 - - - C - - - FAD dependent oxidoreductase
HMIFHPHL_00193 1.73e-126 - - - K - - - Helix-turn-helix domain
HMIFHPHL_00194 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HMIFHPHL_00195 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HMIFHPHL_00196 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
HMIFHPHL_00197 5.33e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMIFHPHL_00198 2.61e-282 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
HMIFHPHL_00199 4.91e-111 - - - - - - - -
HMIFHPHL_00200 5.62e-75 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HMIFHPHL_00201 7.19e-68 - - - - - - - -
HMIFHPHL_00202 3.51e-125 - - - - - - - -
HMIFHPHL_00203 2.98e-90 - - - - - - - -
HMIFHPHL_00204 1.2e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
HMIFHPHL_00205 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
HMIFHPHL_00206 2.21e-127 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
HMIFHPHL_00207 2.8e-161 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
HMIFHPHL_00208 1.65e-295 pts3C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMIFHPHL_00209 6.14e-53 - - - - - - - -
HMIFHPHL_00210 2.65e-269 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HMIFHPHL_00211 2.45e-269 dho 3.5.2.3 - S ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Amidohydrolase family
HMIFHPHL_00212 5.06e-259 selA 2.9.1.1 - H ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 L-seryl-tRNA selenium transferase
HMIFHPHL_00213 1.74e-166 - 4.1.2.14 - S ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 ko00000,ko00001,ko00002,ko01000 KDGP aldolase
HMIFHPHL_00214 3.34e-244 - 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
HMIFHPHL_00215 2.13e-124 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
HMIFHPHL_00216 5.78e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HMIFHPHL_00217 7.54e-211 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HMIFHPHL_00218 6.72e-203 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
HMIFHPHL_00219 1.27e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HMIFHPHL_00220 7.55e-58 - - - S - - - Protein of unknown function (DUF2089)
HMIFHPHL_00221 1.1e-56 - - - - - - - -
HMIFHPHL_00222 1.68e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
HMIFHPHL_00223 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HMIFHPHL_00224 0.0 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HMIFHPHL_00225 0.0 pts5ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HMIFHPHL_00226 2.13e-184 - - - - - - - -
HMIFHPHL_00227 6.2e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HMIFHPHL_00228 7.84e-92 - - - - - - - -
HMIFHPHL_00229 8.9e-96 ywnA - - K - - - Transcriptional regulator
HMIFHPHL_00230 5.2e-156 - - - K - - - Bacterial regulatory proteins, tetR family
HMIFHPHL_00231 4.02e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HMIFHPHL_00232 1.15e-152 - - - - - - - -
HMIFHPHL_00233 2.41e-56 - - - - - - - -
HMIFHPHL_00234 1.55e-55 - - - - - - - -
HMIFHPHL_00235 0.0 ydiC - - EGP - - - Major Facilitator
HMIFHPHL_00236 3.66e-85 - - - K - - - helix_turn_helix, mercury resistance
HMIFHPHL_00237 1.15e-147 hpk2 - - T - - - Histidine kinase
HMIFHPHL_00238 1.4e-148 hpk2 - - T - - - Histidine kinase
HMIFHPHL_00239 3.28e-166 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
HMIFHPHL_00240 2.42e-65 - - - - - - - -
HMIFHPHL_00241 1.96e-167 yidA - - K - - - Helix-turn-helix domain, rpiR family
HMIFHPHL_00242 6.86e-311 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMIFHPHL_00243 3.35e-75 - - - - - - - -
HMIFHPHL_00244 2.87e-56 - - - - - - - -
HMIFHPHL_00245 1.76e-236 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HMIFHPHL_00246 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
HMIFHPHL_00247 1.49e-63 - - - - - - - -
HMIFHPHL_00248 2.04e-158 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HMIFHPHL_00249 1.17e-135 - - - K - - - transcriptional regulator
HMIFHPHL_00250 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
HMIFHPHL_00251 8.31e-139 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HMIFHPHL_00252 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
HMIFHPHL_00253 1.84e-295 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HMIFHPHL_00254 4.87e-156 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HMIFHPHL_00255 1.13e-171 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
HMIFHPHL_00256 4.75e-157 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HMIFHPHL_00257 1.01e-47 - - - M - - - LysM domain protein
HMIFHPHL_00258 1.43e-82 - - - M - - - LysM domain protein
HMIFHPHL_00259 4.2e-88 gcsH1 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Glycine cleavage H-protein
HMIFHPHL_00260 9.03e-229 - - - - - - - -
HMIFHPHL_00261 6.88e-170 - - - - - - - -
HMIFHPHL_00262 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
HMIFHPHL_00263 2.03e-75 - - - - - - - -
HMIFHPHL_00264 9.17e-285 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMIFHPHL_00265 1.08e-101 - - - S ko:K02348 - ko00000 GNAT family
HMIFHPHL_00266 1.24e-99 - - - K - - - Transcriptional regulator
HMIFHPHL_00267 1.17e-288 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HMIFHPHL_00268 1.79e-52 - - - - - - - -
HMIFHPHL_00269 5.3e-265 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HMIFHPHL_00270 5.58e-181 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HMIFHPHL_00271 3.14e-190 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HMIFHPHL_00272 8.8e-264 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HMIFHPHL_00273 3.02e-124 - - - K - - - Cupin domain
HMIFHPHL_00274 8.08e-110 - - - S - - - ASCH
HMIFHPHL_00275 1.88e-111 - - - K - - - GNAT family
HMIFHPHL_00276 2.05e-115 - - - K - - - acetyltransferase
HMIFHPHL_00277 2.06e-30 - - - - - - - -
HMIFHPHL_00278 5.05e-79 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HMIFHPHL_00279 1.85e-208 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HMIFHPHL_00280 1.08e-243 - - - - - - - -
HMIFHPHL_00281 0.0 acdH 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
HMIFHPHL_00282 8.16e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
HMIFHPHL_00283 2.36e-305 xylP1 - - G - - - MFS/sugar transport protein
HMIFHPHL_00284 1.43e-170 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
HMIFHPHL_00285 3.48e-40 - - - - - - - -
HMIFHPHL_00286 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HMIFHPHL_00287 6.4e-54 - - - - - - - -
HMIFHPHL_00288 1.54e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HMIFHPHL_00289 2.48e-226 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HMIFHPHL_00290 4.03e-81 - - - S - - - CHY zinc finger
HMIFHPHL_00291 6.62e-286 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HMIFHPHL_00292 1.1e-280 - - - - - - - -
HMIFHPHL_00293 8.13e-199 tagG - - U ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
HMIFHPHL_00294 9.42e-258 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HMIFHPHL_00295 6.53e-58 - - - - - - - -
HMIFHPHL_00296 4.63e-119 - - - K - - - Transcriptional regulator PadR-like family
HMIFHPHL_00297 0.0 - - - P - - - Major Facilitator Superfamily
HMIFHPHL_00298 3.5e-307 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
HMIFHPHL_00299 2.12e-225 hicD1 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HMIFHPHL_00300 8.95e-60 - - - - - - - -
HMIFHPHL_00301 1.22e-131 zmp1 - - O - - - Zinc-dependent metalloprotease
HMIFHPHL_00302 1.44e-154 rpiA2 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HMIFHPHL_00303 0.0 sufI - - Q - - - Multicopper oxidase
HMIFHPHL_00304 5.34e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
HMIFHPHL_00305 1.31e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HMIFHPHL_00306 3.25e-294 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HMIFHPHL_00307 5.89e-108 - - - K - - - Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HMIFHPHL_00308 2.16e-103 - - - - - - - -
HMIFHPHL_00309 3.45e-103 accB3 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HMIFHPHL_00310 1.49e-223 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
HMIFHPHL_00311 4.67e-205 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HMIFHPHL_00312 3.34e-101 - 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA-DNA hybrid ribonuclease activity
HMIFHPHL_00313 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HMIFHPHL_00314 4.47e-229 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_00315 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulphide oxidoreductase
HMIFHPHL_00316 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMIFHPHL_00317 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
HMIFHPHL_00318 3.55e-173 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HMIFHPHL_00319 0.0 - - - M - - - domain protein
HMIFHPHL_00320 1.24e-166 - - - M - - - dTDP-4-dehydrorhamnose reductase activity
HMIFHPHL_00321 2.23e-97 - - - - - - - -
HMIFHPHL_00322 1.4e-53 - - - - - - - -
HMIFHPHL_00323 5.32e-51 - - - - - - - -
HMIFHPHL_00324 4.56e-154 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HMIFHPHL_00325 1.84e-261 - - - EGP - - - Transporter, major facilitator family protein
HMIFHPHL_00326 5.9e-188 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
HMIFHPHL_00327 3.91e-211 - - - K - - - Transcriptional regulator
HMIFHPHL_00328 2.8e-190 - - - S - - - hydrolase
HMIFHPHL_00330 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HMIFHPHL_00331 8.8e-265 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HMIFHPHL_00334 4.45e-149 - - - - - - - -
HMIFHPHL_00336 3.04e-140 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HMIFHPHL_00337 3.44e-53 plnD - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HMIFHPHL_00338 2.48e-52 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
HMIFHPHL_00339 1.03e-201 is18 - - L - - - Integrase core domain
HMIFHPHL_00340 1.17e-94 plnD - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HMIFHPHL_00341 3.87e-165 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HMIFHPHL_00342 1.93e-31 plnF - - - - - - -
HMIFHPHL_00343 8.82e-32 - - - - - - - -
HMIFHPHL_00344 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HMIFHPHL_00345 6.08e-309 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
HMIFHPHL_00346 5.49e-142 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HMIFHPHL_00347 1.1e-20 plnU - - S ko:K07052 - ko00000 CAAX protease self-immunity
HMIFHPHL_00348 2.83e-80 plnU - - S ko:K07052 - ko00000 CAAX protease self-immunity
HMIFHPHL_00349 5.64e-130 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
HMIFHPHL_00350 3.34e-147 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HMIFHPHL_00351 5.5e-42 - - - - - - - -
HMIFHPHL_00352 0.0 - - - L - - - DNA helicase
HMIFHPHL_00353 5.87e-181 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
HMIFHPHL_00354 8.19e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HMIFHPHL_00355 2.12e-163 - - - K - - - UbiC transcription regulator-associated domain protein
HMIFHPHL_00356 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMIFHPHL_00357 9.68e-34 - - - - - - - -
HMIFHPHL_00358 3.55e-99 - - - S - - - Domain of unknown function (DUF3284)
HMIFHPHL_00359 0.0 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMIFHPHL_00360 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HMIFHPHL_00361 6.97e-209 - - - GK - - - ROK family
HMIFHPHL_00362 9.75e-175 yecA - - K - - - Helix-turn-helix domain, rpiR family
HMIFHPHL_00363 3.43e-243 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMIFHPHL_00364 4.28e-263 - - - - - - - -
HMIFHPHL_00365 5.08e-194 - - - S - - - Psort location Cytoplasmic, score
HMIFHPHL_00366 2.35e-215 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HMIFHPHL_00367 1.37e-290 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
HMIFHPHL_00368 4.65e-229 - - - - - - - -
HMIFHPHL_00369 2.14e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
HMIFHPHL_00370 1.12e-205 yunF - - F - - - Protein of unknown function DUF72
HMIFHPHL_00371 5.43e-91 - - - F - - - DNA mismatch repair protein MutT
HMIFHPHL_00372 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMIFHPHL_00373 1.49e-272 - - - EGP ko:K02030 - ko00000,ko00002,ko02000 Drug resistance transporter Bcr CflA subfamily
HMIFHPHL_00374 1.63e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
HMIFHPHL_00375 1.6e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HMIFHPHL_00376 2.5e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HMIFHPHL_00377 6.87e-50 veg - - S - - - Biofilm formation stimulator VEG
HMIFHPHL_00378 1.07e-207 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HMIFHPHL_00379 1.9e-230 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
HMIFHPHL_00380 8.05e-166 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HMIFHPHL_00381 6.39e-169 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HMIFHPHL_00382 1.96e-189 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HMIFHPHL_00383 3.28e-298 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMIFHPHL_00384 2.82e-196 bla1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HMIFHPHL_00385 3.26e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMIFHPHL_00386 1.82e-232 - - - S - - - DUF218 domain
HMIFHPHL_00387 3.53e-178 - - - - - - - -
HMIFHPHL_00388 9.78e-190 yxeH - - S - - - hydrolase
HMIFHPHL_00389 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
HMIFHPHL_00390 2.46e-197 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
HMIFHPHL_00391 2.87e-101 ywiB - - S - - - Domain of unknown function (DUF1934)
HMIFHPHL_00392 2.96e-89 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HMIFHPHL_00393 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMIFHPHL_00394 5.84e-312 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMIFHPHL_00395 2.28e-290 sdaC - - E ko:K03837 - ko00000,ko02000 amino acid
HMIFHPHL_00396 7.51e-159 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HMIFHPHL_00397 2.81e-202 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HMIFHPHL_00398 6.59e-170 - - - S - - - YheO-like PAS domain
HMIFHPHL_00399 4.01e-36 - - - - - - - -
HMIFHPHL_00400 2.08e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMIFHPHL_00401 1.26e-305 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HMIFHPHL_00402 1.91e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HMIFHPHL_00403 1.49e-273 - - - J - - - translation release factor activity
HMIFHPHL_00404 3.14e-164 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
HMIFHPHL_00405 1.79e-119 lemA - - S ko:K03744 - ko00000 LemA family
HMIFHPHL_00406 5.58e-195 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HMIFHPHL_00407 1.84e-189 - - - - - - - -
HMIFHPHL_00408 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HMIFHPHL_00409 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HMIFHPHL_00410 9.32e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HMIFHPHL_00411 5e-275 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMIFHPHL_00412 2.58e-85 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HMIFHPHL_00413 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HMIFHPHL_00414 2.77e-248 - - - P ko:K02051 - ko00000,ko00002,ko02000 ABC transporter, substratebinding protein
HMIFHPHL_00415 1.06e-202 - - - U ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMIFHPHL_00416 2.02e-171 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HMIFHPHL_00417 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HMIFHPHL_00418 4.32e-259 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HMIFHPHL_00419 2.09e-243 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HMIFHPHL_00420 1.61e-292 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HMIFHPHL_00421 2.36e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HMIFHPHL_00422 2.12e-274 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
HMIFHPHL_00423 2.63e-241 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMIFHPHL_00424 1.3e-110 queT - - S - - - QueT transporter
HMIFHPHL_00425 4.87e-148 - - - S - - - (CBS) domain
HMIFHPHL_00426 0.0 - - - S - - - Putative peptidoglycan binding domain
HMIFHPHL_00427 2.79e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HMIFHPHL_00428 8.29e-129 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HMIFHPHL_00429 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMIFHPHL_00430 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HMIFHPHL_00431 7.72e-57 yabO - - J - - - S4 domain protein
HMIFHPHL_00433 2.02e-83 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HMIFHPHL_00434 1.07e-103 yabR - - J ko:K07571 - ko00000 RNA binding
HMIFHPHL_00435 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMIFHPHL_00436 4.3e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HMIFHPHL_00437 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMIFHPHL_00438 1.93e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HMIFHPHL_00439 5.33e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMIFHPHL_00440 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HMIFHPHL_00441 8.74e-09 - - - L ko:K07487 - ko00000 Transposase
HMIFHPHL_00444 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HMIFHPHL_00445 1.5e-194 - - - S - - - Calcineurin-like phosphoesterase
HMIFHPHL_00449 9.02e-66 - - - S - - - Cupin 2, conserved barrel domain protein
HMIFHPHL_00450 1.38e-71 - - - S - - - Cupin domain
HMIFHPHL_00451 1.31e-213 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
HMIFHPHL_00452 9.2e-247 ysdE - - P - - - Citrate transporter
HMIFHPHL_00453 1.06e-195 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HMIFHPHL_00454 1.08e-174 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMIFHPHL_00455 6.88e-279 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMIFHPHL_00456 5.41e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HMIFHPHL_00457 2.31e-176 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HMIFHPHL_00458 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMIFHPHL_00459 5.27e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HMIFHPHL_00460 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HMIFHPHL_00461 6.3e-95 - - - - ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 -
HMIFHPHL_00462 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
HMIFHPHL_00463 3.76e-107 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HMIFHPHL_00464 1.71e-302 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HMIFHPHL_00465 8.77e-204 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HMIFHPHL_00467 6.84e-158 - - - G - - - Peptidase_C39 like family
HMIFHPHL_00468 6.46e-218 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HMIFHPHL_00469 4.51e-172 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
HMIFHPHL_00470 4.22e-216 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
HMIFHPHL_00471 9.05e-85 manO - - S - - - Domain of unknown function (DUF956)
HMIFHPHL_00472 0.0 levR - - K - - - Sigma-54 interaction domain
HMIFHPHL_00473 7.19e-94 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HMIFHPHL_00474 4.5e-113 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HMIFHPHL_00475 2.58e-228 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMIFHPHL_00476 1.87e-84 accB1 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin-requiring enzyme
HMIFHPHL_00477 4.82e-315 accC1 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase C-terminal domain
HMIFHPHL_00478 6.07e-183 accD1 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HMIFHPHL_00479 1.23e-177 accA1 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HMIFHPHL_00480 1.32e-233 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HMIFHPHL_00481 7.53e-215 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
HMIFHPHL_00482 7.04e-226 - - - EG - - - EamA-like transporter family
HMIFHPHL_00483 1.91e-165 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMIFHPHL_00484 1.12e-147 zmp2 - - O - - - Zinc-dependent metalloprotease
HMIFHPHL_00485 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HMIFHPHL_00486 1.62e-158 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HMIFHPHL_00487 8.47e-69 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
HMIFHPHL_00488 9.43e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
HMIFHPHL_00489 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HMIFHPHL_00490 4.91e-265 yacL - - S - - - domain protein
HMIFHPHL_00491 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMIFHPHL_00492 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HMIFHPHL_00493 1.35e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HMIFHPHL_00494 1.49e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMIFHPHL_00495 5.87e-127 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
HMIFHPHL_00496 4.58e-130 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
HMIFHPHL_00497 4.55e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HMIFHPHL_00498 1e-39 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HMIFHPHL_00499 1.89e-128 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HMIFHPHL_00500 2.81e-202 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HMIFHPHL_00501 9.76e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMIFHPHL_00502 2.69e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMIFHPHL_00503 3.72e-105 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMIFHPHL_00504 2.76e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMIFHPHL_00505 8.29e-226 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HMIFHPHL_00506 2.26e-84 - - - L - - - nuclease
HMIFHPHL_00507 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMIFHPHL_00508 5.03e-50 - - - K - - - Helix-turn-helix domain
HMIFHPHL_00509 2.37e-140 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HMIFHPHL_00510 2.47e-253 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMIFHPHL_00511 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMIFHPHL_00512 8.42e-50 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
HMIFHPHL_00513 6.7e-141 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HMIFHPHL_00514 1.26e-117 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMIFHPHL_00515 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMIFHPHL_00516 1.39e-60 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HMIFHPHL_00517 6.22e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMIFHPHL_00518 1.01e-51 yaaL - - S - - - Protein of unknown function (DUF2508)
HMIFHPHL_00519 1.56e-296 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMIFHPHL_00520 4.97e-67 - 2.7.1.194 - G ko:K02821,ko:K03483 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMIFHPHL_00521 3.77e-53 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HMIFHPHL_00522 4.67e-280 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HMIFHPHL_00523 1.16e-128 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
HMIFHPHL_00524 1.05e-151 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMIFHPHL_00525 1.39e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
HMIFHPHL_00526 2.33e-239 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HMIFHPHL_00527 8.46e-77 yabA - - L - - - Involved in initiation control of chromosome replication
HMIFHPHL_00528 2.64e-213 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMIFHPHL_00529 3.17e-191 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HMIFHPHL_00530 4.95e-246 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HMIFHPHL_00531 3.77e-270 phnW 2.6.1.37 - E ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000,ko01007 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HMIFHPHL_00532 2.8e-187 phnX 3.11.1.1 - E ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the HAD-like hydrolase superfamily. PhnX family
HMIFHPHL_00533 3.33e-184 phnE1 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HMIFHPHL_00534 6.51e-178 phnE2 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter permease
HMIFHPHL_00535 3.12e-175 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HMIFHPHL_00536 3.46e-242 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
HMIFHPHL_00537 6.84e-167 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
HMIFHPHL_00538 4.66e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
HMIFHPHL_00539 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HMIFHPHL_00540 2.1e-248 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMIFHPHL_00541 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
HMIFHPHL_00542 3.67e-154 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HMIFHPHL_00543 2.38e-140 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
HMIFHPHL_00544 9.82e-55 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMIFHPHL_00545 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMIFHPHL_00546 0.0 ydaO - - E - - - amino acid
HMIFHPHL_00547 7.29e-247 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
HMIFHPHL_00548 6.57e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HMIFHPHL_00549 3.7e-149 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
HMIFHPHL_00550 7.63e-14 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
HMIFHPHL_00551 4.55e-275 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
HMIFHPHL_00552 2.94e-164 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
HMIFHPHL_00553 1.27e-129 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HMIFHPHL_00554 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMIFHPHL_00555 1.69e-257 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HMIFHPHL_00556 1.28e-276 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
HMIFHPHL_00557 1.49e-170 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HMIFHPHL_00558 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMIFHPHL_00559 6.91e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HMIFHPHL_00560 2.22e-206 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HMIFHPHL_00561 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
HMIFHPHL_00562 9.78e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMIFHPHL_00563 2.31e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMIFHPHL_00564 1.55e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HMIFHPHL_00565 2.78e-65 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
HMIFHPHL_00566 2.87e-71 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
HMIFHPHL_00567 2.55e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HMIFHPHL_00568 1.04e-211 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMIFHPHL_00569 1.34e-233 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HMIFHPHL_00570 1.13e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HMIFHPHL_00571 6.37e-160 - - - T - - - Putative diguanylate phosphodiesterase
HMIFHPHL_00572 0.0 nox - - C - - - NADH oxidase
HMIFHPHL_00573 3.69e-206 ydaJ - - G - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
HMIFHPHL_00574 2.45e-310 - - - - - - - -
HMIFHPHL_00575 3.93e-255 - - - S - - - Protein conserved in bacteria
HMIFHPHL_00576 2.74e-277 ydaM - - M - - - Glycosyl transferase family group 2
HMIFHPHL_00577 1.27e-147 - - - S - - - Bacterial cellulose synthase subunit
HMIFHPHL_00578 1.46e-222 - - - S - - - Bacterial cellulose synthase subunit
HMIFHPHL_00579 7.91e-172 - - - T - - - diguanylate cyclase activity
HMIFHPHL_00580 8.65e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HMIFHPHL_00581 4.31e-141 yviA - - S - - - Protein of unknown function (DUF421)
HMIFHPHL_00582 7.54e-99 - - - S - - - Protein of unknown function (DUF3290)
HMIFHPHL_00583 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HMIFHPHL_00584 2.4e-169 - - - T - - - Putative diguanylate phosphodiesterase
HMIFHPHL_00585 0.0 nox2 - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HMIFHPHL_00586 1.89e-134 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HMIFHPHL_00587 5.33e-268 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
HMIFHPHL_00588 9.45e-152 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
HMIFHPHL_00589 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMIFHPHL_00590 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HMIFHPHL_00591 2.21e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HMIFHPHL_00592 7.5e-302 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HMIFHPHL_00593 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HMIFHPHL_00594 8.62e-114 - - - S - - - Short repeat of unknown function (DUF308)
HMIFHPHL_00595 1.4e-206 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HMIFHPHL_00596 9.2e-243 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HMIFHPHL_00597 1.21e-215 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HMIFHPHL_00598 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HMIFHPHL_00599 1.55e-225 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMIFHPHL_00600 5.11e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMIFHPHL_00602 1.14e-311 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
HMIFHPHL_00603 5.75e-242 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
HMIFHPHL_00604 2.02e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMIFHPHL_00605 1.31e-285 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HMIFHPHL_00606 7.15e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMIFHPHL_00607 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMIFHPHL_00608 2.42e-169 - - - - - - - -
HMIFHPHL_00609 0.0 eriC - - P ko:K03281 - ko00000 chloride
HMIFHPHL_00610 1.76e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HMIFHPHL_00611 6.62e-180 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
HMIFHPHL_00612 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HMIFHPHL_00613 2.4e-107 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HMIFHPHL_00614 5.92e-268 - - - M - - - Domain of unknown function (DUF5011)
HMIFHPHL_00615 6.32e-146 - - - M - - - Domain of unknown function (DUF5011)
HMIFHPHL_00616 0.0 - - - M - - - Domain of unknown function (DUF5011)
HMIFHPHL_00617 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HMIFHPHL_00618 9.36e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_00619 7.98e-137 - - - - - - - -
HMIFHPHL_00620 1.98e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
HMIFHPHL_00621 5.71e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HMIFHPHL_00622 3.52e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
HMIFHPHL_00623 1.07e-104 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
HMIFHPHL_00624 2.52e-114 - - - J - - - Acetyltransferase (GNAT) domain
HMIFHPHL_00625 7.18e-131 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HMIFHPHL_00626 2.53e-198 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HMIFHPHL_00627 3.09e-213 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
HMIFHPHL_00628 6.24e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HMIFHPHL_00629 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
HMIFHPHL_00630 3.07e-119 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HMIFHPHL_00631 5.68e-156 - - - S - - - Protein of unknown function (DUF1361)
HMIFHPHL_00632 8.33e-192 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMIFHPHL_00633 2.18e-182 ybbR - - S - - - YbbR-like protein
HMIFHPHL_00634 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMIFHPHL_00635 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMIFHPHL_00636 3.15e-158 - - - T - - - EAL domain
HMIFHPHL_00637 3.82e-188 - 3.1.3.23 - S ko:K07757 - ko00000,ko01000 Sucrose-6F-phosphate phosphohydrolase
HMIFHPHL_00638 1.21e-135 - - - K - - - Bacterial regulatory proteins, tetR family
HMIFHPHL_00639 2.07e-263 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HMIFHPHL_00640 3.38e-70 - - - - - - - -
HMIFHPHL_00641 2.49e-95 - - - - - - - -
HMIFHPHL_00642 7.06e-169 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
HMIFHPHL_00643 7.34e-180 - - - EGP - - - Transmembrane secretion effector
HMIFHPHL_00644 2.09e-42 - - - G ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
HMIFHPHL_00645 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMIFHPHL_00646 2.91e-182 - - - - - - - -
HMIFHPHL_00648 5.45e-94 spx1 - - P ko:K16509 - ko00000 ArsC family
HMIFHPHL_00649 3.88e-46 - - - - - - - -
HMIFHPHL_00650 8.47e-117 - - - V - - - VanZ like family
HMIFHPHL_00651 1.31e-315 - - - EGP - - - Major Facilitator
HMIFHPHL_00652 4.45e-226 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HMIFHPHL_00653 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HMIFHPHL_00654 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HMIFHPHL_00655 2.72e-196 licD - - M ko:K07271 - ko00000,ko01000 LicD family
HMIFHPHL_00656 6.16e-107 - - - K - - - Transcriptional regulator
HMIFHPHL_00657 1.36e-27 - - - - - - - -
HMIFHPHL_00658 1.79e-287 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HMIFHPHL_00659 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HMIFHPHL_00660 3.16e-197 ribC1 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HMIFHPHL_00661 0.0 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HMIFHPHL_00662 6.37e-232 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HMIFHPHL_00663 1.23e-229 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HMIFHPHL_00664 0.0 oatA - - I - - - Acyltransferase
HMIFHPHL_00665 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HMIFHPHL_00666 1.89e-90 - - - O - - - OsmC-like protein
HMIFHPHL_00667 3.8e-61 - - - - - - - -
HMIFHPHL_00668 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
HMIFHPHL_00669 6.12e-115 - - - - - - - -
HMIFHPHL_00670 5.24e-191 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
HMIFHPHL_00671 7.48e-96 - - - F - - - Nudix hydrolase
HMIFHPHL_00672 1.48e-27 - - - - - - - -
HMIFHPHL_00673 7.32e-136 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
HMIFHPHL_00674 2.02e-106 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HMIFHPHL_00675 8.84e-18 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
HMIFHPHL_00676 1.01e-188 - - - - - - - -
HMIFHPHL_00677 1.99e-145 gph1 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant
HMIFHPHL_00678 3.21e-268 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HMIFHPHL_00679 1.03e-217 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMIFHPHL_00680 1.28e-54 - - - - - - - -
HMIFHPHL_00682 2.3e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_00683 3.39e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HMIFHPHL_00684 3.14e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HMIFHPHL_00685 1.27e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HMIFHPHL_00686 2.1e-109 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HMIFHPHL_00687 4.68e-198 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HMIFHPHL_00688 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HMIFHPHL_00689 1.57e-182 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
HMIFHPHL_00690 0.0 steT - - E ko:K03294 - ko00000 amino acid
HMIFHPHL_00691 3.1e-96 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HMIFHPHL_00692 1.03e-189 - - - S - - - Sulfite exporter TauE/SafE
HMIFHPHL_00693 2.96e-91 - - - K - - - MarR family
HMIFHPHL_00694 2.27e-269 - - - EGP - - - Major Facilitator Superfamily
HMIFHPHL_00695 2.93e-109 - - - S ko:K07090 - ko00000 membrane transporter protein
HMIFHPHL_00696 3.36e-124 - - - K - - - Bacterial regulatory proteins, tetR family
HMIFHPHL_00697 1.7e-299 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HMIFHPHL_00698 4.6e-102 rppH3 - - F - - - NUDIX domain
HMIFHPHL_00699 3.5e-64 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
HMIFHPHL_00700 1.61e-36 - - - - - - - -
HMIFHPHL_00701 1.35e-165 pgm3 - - G - - - Phosphoglycerate mutase family
HMIFHPHL_00702 2.07e-161 gpm2 - - G - - - Phosphoglycerate mutase family
HMIFHPHL_00703 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
HMIFHPHL_00704 1.19e-226 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HMIFHPHL_00705 1.08e-27 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HMIFHPHL_00706 4.28e-89 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HMIFHPHL_00707 1.15e-59 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HMIFHPHL_00708 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HMIFHPHL_00709 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HMIFHPHL_00710 5.07e-118 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
HMIFHPHL_00711 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HMIFHPHL_00712 1.46e-211 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
HMIFHPHL_00713 1.22e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HMIFHPHL_00714 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HMIFHPHL_00715 1.08e-71 - - - - - - - -
HMIFHPHL_00716 5.57e-83 - - - K - - - Helix-turn-helix domain
HMIFHPHL_00717 0.0 - - - L - - - AAA domain
HMIFHPHL_00718 2.01e-149 XK27_07075 - - V ko:K07052 - ko00000 CAAX protease self-immunity
HMIFHPHL_00719 1.85e-75 - - - K - - - HxlR-like helix-turn-helix
HMIFHPHL_00720 1.36e-301 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
HMIFHPHL_00721 3.61e-281 - - - S - - - Cysteine-rich secretory protein family
HMIFHPHL_00722 2.09e-60 - - - S - - - MORN repeat
HMIFHPHL_00723 0.0 XK27_09800 - - I - - - Acyltransferase family
HMIFHPHL_00724 1.81e-50 ydaS - - S - - - Transglycosylase associated protein
HMIFHPHL_00725 1.95e-116 - - - - - - - -
HMIFHPHL_00726 5.74e-32 - - - - - - - -
HMIFHPHL_00727 1.1e-93 asp1 - - S - - - Asp23 family, cell envelope-related function
HMIFHPHL_00728 1.04e-94 asp2 - - S - - - Asp23 family, cell envelope-related function
HMIFHPHL_00729 3.91e-190 yisK 3.7.1.5, 4.1.1.68 - Q ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Fumarylacetoacetate (FAA) hydrolase family
HMIFHPHL_00730 7.69e-214 yjdB - - S - - - Domain of unknown function (DUF4767)
HMIFHPHL_00731 5.21e-62 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
HMIFHPHL_00732 8.9e-131 - - - G - - - Glycogen debranching enzyme
HMIFHPHL_00733 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
HMIFHPHL_00734 0.0 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HMIFHPHL_00735 3.94e-59 - - - S - - - MazG-like family
HMIFHPHL_00736 3.83e-116 XK27_09665 - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
HMIFHPHL_00737 0.0 - - - M - - - MucBP domain
HMIFHPHL_00738 5.65e-269 - - - M - - - MucBP domain
HMIFHPHL_00739 1.42e-08 - - - - - - - -
HMIFHPHL_00740 1.27e-115 - - - S - - - AAA domain
HMIFHPHL_00741 1.83e-180 - - - K - - - sequence-specific DNA binding
HMIFHPHL_00742 1.09e-123 - - - K - - - Helix-turn-helix domain
HMIFHPHL_00743 6.52e-219 - - - K - - - Transcriptional regulator
HMIFHPHL_00744 0.0 - - - C - - - FMN_bind
HMIFHPHL_00746 3.54e-105 - - - K - - - Transcriptional regulator
HMIFHPHL_00747 4.71e-149 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HMIFHPHL_00748 6.25e-149 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HMIFHPHL_00749 6.04e-161 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HMIFHPHL_00750 3.39e-255 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
HMIFHPHL_00751 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HMIFHPHL_00752 2.19e-289 - - - L - - - DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HMIFHPHL_00753 9.05e-55 - - - - - - - -
HMIFHPHL_00754 4.95e-44 - - - L - - - leucine-zipper of insertion element IS481
HMIFHPHL_00755 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HMIFHPHL_00756 4.05e-210 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HMIFHPHL_00757 5.06e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HMIFHPHL_00758 8.34e-179 - - - S - - - NADPH-dependent FMN reductase
HMIFHPHL_00759 5.55e-244 - - - - - - - -
HMIFHPHL_00760 1.89e-277 yibE - - S - - - overlaps another CDS with the same product name
HMIFHPHL_00761 8.44e-163 yibF - - S - - - overlaps another CDS with the same product name
HMIFHPHL_00762 5.57e-131 - - - K - - - FR47-like protein
HMIFHPHL_00763 1.5e-156 gpm5 - - G - - - Phosphoglycerate mutase family
HMIFHPHL_00764 3.33e-64 - - - - - - - -
HMIFHPHL_00765 2.1e-246 - - - I - - - alpha/beta hydrolase fold
HMIFHPHL_00766 0.0 xylP2 - - G - - - symporter
HMIFHPHL_00767 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMIFHPHL_00768 1.2e-281 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
HMIFHPHL_00769 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HMIFHPHL_00770 2.41e-66 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
HMIFHPHL_00771 4.09e-155 azlC - - E - - - branched-chain amino acid
HMIFHPHL_00772 1.75e-47 - - - K - - - MerR HTH family regulatory protein
HMIFHPHL_00773 1.46e-170 - - - - - - - -
HMIFHPHL_00774 1.57e-151 - - - S - - - Domain of unknown function (DUF4811)
HMIFHPHL_00775 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HMIFHPHL_00776 4.51e-111 - - - K - - - MerR HTH family regulatory protein
HMIFHPHL_00777 1.36e-77 - - - - - - - -
HMIFHPHL_00778 2.94e-155 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
HMIFHPHL_00779 1.78e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HMIFHPHL_00780 3.78e-168 - - - S - - - Putative threonine/serine exporter
HMIFHPHL_00781 7.76e-100 - - - S - - - Threonine/Serine exporter, ThrE
HMIFHPHL_00782 2.34e-242 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HMIFHPHL_00783 2.05e-153 - - - I - - - phosphatase
HMIFHPHL_00784 1.11e-197 - - - I - - - alpha/beta hydrolase fold
HMIFHPHL_00785 3.03e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HMIFHPHL_00786 1.7e-118 - - - K - - - Transcriptional regulator
HMIFHPHL_00787 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HMIFHPHL_00788 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
HMIFHPHL_00789 1.29e-153 dacB 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
HMIFHPHL_00790 1.11e-148 dgk2 - - F - - - deoxynucleoside kinase
HMIFHPHL_00791 4.64e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMIFHPHL_00799 9.78e-102 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HMIFHPHL_00800 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMIFHPHL_00801 1.16e-140 - - - K - - - Bacterial regulatory proteins, tetR family
HMIFHPHL_00802 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMIFHPHL_00803 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMIFHPHL_00804 1.81e-150 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
HMIFHPHL_00805 4.19e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HMIFHPHL_00806 1.19e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HMIFHPHL_00807 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMIFHPHL_00808 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HMIFHPHL_00809 4.34e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMIFHPHL_00810 9.83e-141 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HMIFHPHL_00811 2.27e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HMIFHPHL_00812 6.61e-193 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMIFHPHL_00813 1.85e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HMIFHPHL_00814 3.59e-69 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HMIFHPHL_00815 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HMIFHPHL_00816 8.29e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HMIFHPHL_00817 1.11e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HMIFHPHL_00818 1.96e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HMIFHPHL_00819 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HMIFHPHL_00820 4.8e-66 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HMIFHPHL_00821 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMIFHPHL_00822 4.99e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMIFHPHL_00823 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMIFHPHL_00824 1.75e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMIFHPHL_00825 5.32e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HMIFHPHL_00826 8.44e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HMIFHPHL_00827 1.32e-91 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HMIFHPHL_00828 5.95e-300 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMIFHPHL_00829 1.84e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HMIFHPHL_00830 1.19e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMIFHPHL_00831 9.65e-79 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMIFHPHL_00832 7.71e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMIFHPHL_00833 1.8e-219 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMIFHPHL_00834 7.76e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HMIFHPHL_00835 4.15e-233 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HMIFHPHL_00836 1.41e-122 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
HMIFHPHL_00837 2.19e-111 - - - S - - - NusG domain II
HMIFHPHL_00838 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HMIFHPHL_00839 3.19e-194 - - - S - - - FMN_bind
HMIFHPHL_00840 4.37e-264 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMIFHPHL_00841 1.98e-197 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMIFHPHL_00842 2.01e-211 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMIFHPHL_00843 1.68e-184 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMIFHPHL_00844 3.06e-194 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMIFHPHL_00845 4.58e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMIFHPHL_00846 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HMIFHPHL_00847 8.51e-210 yitS - - S - - - Uncharacterised protein, DegV family COG1307
HMIFHPHL_00848 1.94e-232 - - - S - - - Membrane
HMIFHPHL_00849 1.24e-257 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
HMIFHPHL_00850 1.88e-275 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HMIFHPHL_00851 5.76e-150 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HMIFHPHL_00852 3.89e-210 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMIFHPHL_00853 7.76e-234 aroF 2.5.1.54 - E ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 DAHP synthetase I family
HMIFHPHL_00854 3.14e-254 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HMIFHPHL_00855 3.59e-128 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HMIFHPHL_00856 4.56e-179 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HMIFHPHL_00857 1.51e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
HMIFHPHL_00858 2.34e-146 - 4.2.1.2, 4.2.1.32 - C ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
HMIFHPHL_00859 5.21e-226 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
HMIFHPHL_00860 6.07e-252 - - - K - - - Helix-turn-helix domain
HMIFHPHL_00861 9.07e-196 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HMIFHPHL_00862 2.04e-170 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HMIFHPHL_00863 7.94e-51 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HMIFHPHL_00864 9.85e-186 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
HMIFHPHL_00865 1.29e-87 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HMIFHPHL_00866 2.11e-222 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HMIFHPHL_00867 1.18e-66 - - - - - - - -
HMIFHPHL_00868 9.2e-215 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HMIFHPHL_00869 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HMIFHPHL_00870 8.69e-230 citR - - K - - - sugar-binding domain protein
HMIFHPHL_00871 1.92e-264 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
HMIFHPHL_00872 5.31e-242 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HMIFHPHL_00873 1.23e-58 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
HMIFHPHL_00874 6.7e-210 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
HMIFHPHL_00875 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
HMIFHPHL_00876 9.85e-186 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
HMIFHPHL_00877 4.88e-33 - - - K - - - sequence-specific DNA binding
HMIFHPHL_00879 3.88e-20 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HMIFHPHL_00880 3.02e-180 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HMIFHPHL_00881 1.7e-67 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HMIFHPHL_00882 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HMIFHPHL_00883 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HMIFHPHL_00884 5.03e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HMIFHPHL_00885 4.54e-207 mleR2 - - K - - - LysR family transcriptional regulator
HMIFHPHL_00886 6.5e-215 mleR - - K - - - LysR family
HMIFHPHL_00887 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
HMIFHPHL_00888 2.6e-212 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
HMIFHPHL_00889 0.0 - - - E ko:K03294 - ko00000 Amino Acid
HMIFHPHL_00890 4.37e-128 - - - S - - - ECF transporter, substrate-specific component
HMIFHPHL_00891 2.48e-32 - - - - - - - -
HMIFHPHL_00892 0.0 - - - S ko:K06889 - ko00000 Alpha beta
HMIFHPHL_00893 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
HMIFHPHL_00894 7.76e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
HMIFHPHL_00895 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HMIFHPHL_00896 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HMIFHPHL_00897 3.13e-207 - - - S - - - L,D-transpeptidase catalytic domain
HMIFHPHL_00898 2.11e-233 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HMIFHPHL_00899 8.5e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HMIFHPHL_00900 3.86e-235 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HMIFHPHL_00901 1.69e-146 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
HMIFHPHL_00902 2.01e-134 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HMIFHPHL_00903 4.61e-120 yebE - - S - - - UPF0316 protein
HMIFHPHL_00904 1.39e-279 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HMIFHPHL_00905 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HMIFHPHL_00906 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMIFHPHL_00907 9.48e-263 camS - - S - - - sex pheromone
HMIFHPHL_00908 5.11e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMIFHPHL_00909 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HMIFHPHL_00910 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMIFHPHL_00911 6.46e-242 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
HMIFHPHL_00912 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMIFHPHL_00913 5.56e-130 yobS - - K - - - Bacterial regulatory proteins, tetR family
HMIFHPHL_00914 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
HMIFHPHL_00915 7.06e-307 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMIFHPHL_00916 2.87e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HMIFHPHL_00917 5.63e-196 gntR - - K - - - rpiR family
HMIFHPHL_00918 4.68e-187 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HMIFHPHL_00919 7.34e-83 - - - S - - - Domain of unknown function (DUF4828)
HMIFHPHL_00920 6.22e-43 cspP - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
HMIFHPHL_00921 1.94e-245 mocA - - S - - - Oxidoreductase
HMIFHPHL_00922 5.62e-316 yfmL - - L - - - DEAD DEAH box helicase
HMIFHPHL_00924 3.93e-99 - - - T - - - Universal stress protein family
HMIFHPHL_00925 1.1e-313 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMIFHPHL_00926 1.93e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HMIFHPHL_00928 7.62e-97 - - - - - - - -
HMIFHPHL_00929 1.18e-138 - - - - - - - -
HMIFHPHL_00930 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HMIFHPHL_00931 4.49e-279 pbpX - - V - - - Beta-lactamase
HMIFHPHL_00932 3.2e-265 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HMIFHPHL_00933 1.01e-199 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HMIFHPHL_00934 3.98e-169 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HMIFHPHL_00935 6.08e-277 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HMIFHPHL_00937 2.23e-10 cap5B - - D - - - NUBPL iron-transfer P-loop NTPase
HMIFHPHL_00938 7.12e-09 - - - V - - - Beta-lactamase
HMIFHPHL_00939 1.43e-28 - - - S - - - O-antigen ligase like membrane protein
HMIFHPHL_00940 5.78e-100 cps3J - - M - - - Domain of unknown function (DUF4422)
HMIFHPHL_00941 2e-117 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
HMIFHPHL_00942 1.4e-62 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMIFHPHL_00943 6.89e-68 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
HMIFHPHL_00944 2.02e-214 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HMIFHPHL_00945 1.33e-82 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
HMIFHPHL_00946 2.89e-129 - - - M - - - Parallel beta-helix repeats
HMIFHPHL_00947 2.52e-238 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HMIFHPHL_00948 3.69e-130 - - - L - - - Integrase
HMIFHPHL_00949 0.0 - - - M - - - domain protein
HMIFHPHL_00950 5.36e-97 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HMIFHPHL_00951 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HMIFHPHL_00952 1.38e-155 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
HMIFHPHL_00953 9.02e-70 - - - - - - - -
HMIFHPHL_00954 1.04e-45 - - - S - - - Protein of unknown function (DUF2922)
HMIFHPHL_00955 1.95e-41 - - - - - - - -
HMIFHPHL_00956 8.39e-38 - - - - - - - -
HMIFHPHL_00957 4.14e-132 - - - K - - - DNA-templated transcription, initiation
HMIFHPHL_00958 2.82e-170 - - - - - - - -
HMIFHPHL_00959 1.01e-181 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
HMIFHPHL_00960 6.62e-138 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
HMIFHPHL_00961 1.94e-170 lytE - - M - - - NlpC/P60 family
HMIFHPHL_00962 5.64e-64 - - - K - - - sequence-specific DNA binding
HMIFHPHL_00963 7.17e-39 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
HMIFHPHL_00964 1.67e-166 pbpX - - V - - - Beta-lactamase
HMIFHPHL_00965 2.09e-215 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HMIFHPHL_00966 1.13e-257 yueF - - S - - - AI-2E family transporter
HMIFHPHL_00967 6.04e-94 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
HMIFHPHL_00968 7.89e-290 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
HMIFHPHL_00969 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HMIFHPHL_00970 4.97e-218 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HMIFHPHL_00971 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HMIFHPHL_00972 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HMIFHPHL_00973 0.0 - - - - - - - -
HMIFHPHL_00974 1.49e-252 - - - M - - - MucBP domain
HMIFHPHL_00975 1.36e-208 lysR5 - - K - - - LysR substrate binding domain
HMIFHPHL_00976 1.01e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
HMIFHPHL_00977 3.85e-76 ywjH - - S - - - Protein of unknown function (DUF1634)
HMIFHPHL_00978 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HMIFHPHL_00979 3.44e-210 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMIFHPHL_00980 3.59e-241 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMIFHPHL_00981 4.86e-258 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HMIFHPHL_00982 5.67e-231 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HMIFHPHL_00983 3.4e-85 - - - K - - - Winged helix DNA-binding domain
HMIFHPHL_00984 2.5e-132 - - - L - - - Integrase
HMIFHPHL_00985 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
HMIFHPHL_00986 5.6e-41 - - - - - - - -
HMIFHPHL_00987 1.24e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
HMIFHPHL_00988 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMIFHPHL_00989 1.41e-285 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HMIFHPHL_00990 8.31e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HMIFHPHL_00991 2.16e-241 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMIFHPHL_00992 6.56e-292 dacA2 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HMIFHPHL_00993 7.9e-289 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HMIFHPHL_00994 1.56e-46 ykuJ - - S - - - Protein of unknown function (DUF1797)
HMIFHPHL_00995 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMIFHPHL_00996 1.66e-48 - - - - - - - -
HMIFHPHL_00997 3.83e-30 - - - - - - - -
HMIFHPHL_00998 0.0 traA - - L - - - MobA MobL family protein
HMIFHPHL_00999 3.06e-94 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HMIFHPHL_01000 2.59e-57 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMIFHPHL_01001 2.22e-159 epsB - - M - - - biosynthesis protein
HMIFHPHL_01002 4.78e-163 ywqD - - D - - - Capsular exopolysaccharide family
HMIFHPHL_01003 3.96e-173 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HMIFHPHL_01004 1.62e-227 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
HMIFHPHL_01005 5.43e-156 tuaA - - M - - - Bacterial sugar transferase
HMIFHPHL_01006 8.75e-61 - - - M - - - transferase activity, transferring glycosyl groups
HMIFHPHL_01007 1.52e-65 wcaA - - M - - - Glycosyl transferase family 2
HMIFHPHL_01009 1.78e-23 epsJ1 - - M - - - glycosyl transferase family 2
HMIFHPHL_01011 3.52e-18 - - - L ko:K07497 - ko00000 4.5 Transposon and IS
HMIFHPHL_01012 2.81e-133 cps2J - - S - - - Polysaccharide biosynthesis protein
HMIFHPHL_01013 2.18e-82 - - - L - - - the current gene model (or a revised gene model) may contain a frame shift
HMIFHPHL_01014 4.58e-155 - - - L - - - Transposase and inactivated derivatives, IS30 family
HMIFHPHL_01015 1.99e-69 - - - L - - - recombinase activity
HMIFHPHL_01017 2.7e-79 - - - D - - - AAA domain
HMIFHPHL_01018 9.78e-123 repE - - K - - - Primase C terminal 1 (PriCT-1)
HMIFHPHL_01031 3.26e-119 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
HMIFHPHL_01032 5.46e-238 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
HMIFHPHL_01033 1.25e-124 - - - - - - - -
HMIFHPHL_01034 1.58e-122 - - - K - - - Acetyltransferase (GNAT) domain
HMIFHPHL_01035 2.52e-201 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HMIFHPHL_01036 5.29e-146 - - - K - - - helix_turn_helix, arabinose operon control protein
HMIFHPHL_01037 3.42e-185 lipA - - I - - - Carboxylesterase family
HMIFHPHL_01038 5.91e-208 - - - P - - - Major Facilitator Superfamily
HMIFHPHL_01039 5.42e-142 - - - GK - - - ROK family
HMIFHPHL_01040 9.33e-293 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HMIFHPHL_01041 2.95e-239 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HMIFHPHL_01042 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HMIFHPHL_01043 3.21e-215 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
HMIFHPHL_01044 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HMIFHPHL_01045 3.35e-157 - - - - - - - -
HMIFHPHL_01046 2.78e-273 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMIFHPHL_01047 0.0 mdr - - EGP - - - Major Facilitator
HMIFHPHL_01048 4.01e-301 - - - N - - - Cell shape-determining protein MreB
HMIFHPHL_01049 0.0 - - - S - - - Pfam Methyltransferase
HMIFHPHL_01050 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HMIFHPHL_01051 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HMIFHPHL_01052 9.32e-40 - - - - - - - -
HMIFHPHL_01053 3.54e-121 mraW1 - - J - - - Putative rRNA methylase
HMIFHPHL_01054 1.03e-160 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HMIFHPHL_01055 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HMIFHPHL_01056 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HMIFHPHL_01057 5.04e-176 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HMIFHPHL_01058 5.24e-194 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMIFHPHL_01059 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
HMIFHPHL_01060 2.16e-109 - - - T - - - Belongs to the universal stress protein A family
HMIFHPHL_01061 8.38e-258 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
HMIFHPHL_01062 8.86e-219 ugpA - - U ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMIFHPHL_01063 3.05e-193 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HMIFHPHL_01064 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HMIFHPHL_01065 6.36e-161 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HMIFHPHL_01066 2.07e-155 dgk2 - - F - - - deoxynucleoside kinase
HMIFHPHL_01067 3.55e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HMIFHPHL_01068 1.2e-314 XK27_06930 - - V ko:K01421 - ko00000 domain protein
HMIFHPHL_01070 2.45e-162 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
HMIFHPHL_01071 2.66e-111 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HMIFHPHL_01072 1.49e-225 - - - K ko:K01990 - ko00000,ko00002,ko02000 LytTr DNA-binding domain
HMIFHPHL_01074 2.95e-199 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMIFHPHL_01075 5.2e-85 - - - K - - - helix_turn_helix, mercury resistance
HMIFHPHL_01076 1.64e-151 - - - GM - - - NAD(P)H-binding
HMIFHPHL_01077 9.36e-205 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HMIFHPHL_01078 1.97e-191 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HMIFHPHL_01079 7.83e-140 - - - - - - - -
HMIFHPHL_01080 8.83e-285 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HMIFHPHL_01081 9.01e-179 agrA - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HMIFHPHL_01082 5.37e-74 - - - - - - - -
HMIFHPHL_01083 4.56e-78 - - - - - - - -
HMIFHPHL_01084 4.31e-146 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
HMIFHPHL_01085 2.2e-111 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
HMIFHPHL_01086 8.82e-119 - - - - - - - -
HMIFHPHL_01087 7.12e-62 - - - - - - - -
HMIFHPHL_01088 0.0 uvrA2 - - L - - - ABC transporter
HMIFHPHL_01091 3.27e-91 - - - - - - - -
HMIFHPHL_01092 9.03e-16 - - - - - - - -
HMIFHPHL_01093 3.89e-237 - - - - - - - -
HMIFHPHL_01094 4.91e-117 gtcA1 - - S - - - Teichoic acid glycosylation protein
HMIFHPHL_01095 8.01e-77 - - - S - - - Protein of unknown function (DUF1516)
HMIFHPHL_01096 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HMIFHPHL_01097 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HMIFHPHL_01098 0.0 - - - S - - - Protein conserved in bacteria
HMIFHPHL_01099 7.32e-292 sat 2.7.7.4 - H ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HMIFHPHL_01100 3.72e-145 cysC 2.7.1.25 - F ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HMIFHPHL_01101 2.54e-225 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain
HMIFHPHL_01102 0.0 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
HMIFHPHL_01103 0.0 - - - P - - - Sodium:sulfate symporter transmembrane region
HMIFHPHL_01104 2.69e-316 dinF - - V - - - MatE
HMIFHPHL_01105 1.79e-42 - - - - - - - -
HMIFHPHL_01108 1.21e-103 yybD - - S ko:K02348 - ko00000 Acetyltransferase (GNAT) domain
HMIFHPHL_01109 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HMIFHPHL_01110 4.83e-108 - - - - - - - -
HMIFHPHL_01111 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HMIFHPHL_01112 3.99e-116 - - - - - - - -
HMIFHPHL_01113 0.0 celR - - K - - - PRD domain
HMIFHPHL_01114 2.7e-104 - - - S - - - Domain of unknown function (DUF3284)
HMIFHPHL_01115 2.37e-68 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
HMIFHPHL_01116 4.9e-64 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HMIFHPHL_01117 2.15e-303 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMIFHPHL_01118 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HMIFHPHL_01119 3.13e-274 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
HMIFHPHL_01120 1.72e-148 yciB - - M - - - ErfK YbiS YcfS YnhG
HMIFHPHL_01121 1.65e-46 dltC2 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMIFHPHL_01122 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 Alanine-glyoxylate amino-transferase
HMIFHPHL_01123 3.29e-132 argO - - S ko:K06895 - ko00000,ko02000 LysE type translocator
HMIFHPHL_01124 1.08e-268 arcT - - E - - - Aminotransferase
HMIFHPHL_01125 2.07e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HMIFHPHL_01126 2.43e-18 - - - - - - - -
HMIFHPHL_01127 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HMIFHPHL_01128 9.94e-71 yheA - - S - - - Belongs to the UPF0342 family
HMIFHPHL_01129 6.08e-294 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
HMIFHPHL_01130 0.0 yhaN - - L - - - AAA domain
HMIFHPHL_01131 3.45e-239 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
HMIFHPHL_01132 8.64e-272 - - - - - - - -
HMIFHPHL_01133 6.9e-233 - - - M - - - Peptidase family S41
HMIFHPHL_01134 9.36e-227 - - - K - - - LysR substrate binding domain
HMIFHPHL_01135 9.9e-144 - - - S - - - NADPH-dependent FMN reductase
HMIFHPHL_01136 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HMIFHPHL_01137 1.81e-128 - - - - - - - -
HMIFHPHL_01138 4.08e-101 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
HMIFHPHL_01139 1.15e-235 ykoT - - M - - - Glycosyl transferase family 2
HMIFHPHL_01140 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMIFHPHL_01141 4.29e-26 - - - S - - - NUDIX domain
HMIFHPHL_01142 5.87e-144 - - - S - - - membrane
HMIFHPHL_01143 0.0 - - - S - - - membrane
HMIFHPHL_01144 8.58e-218 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HMIFHPHL_01145 8.71e-111 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
HMIFHPHL_01146 1.86e-287 ribA 3.5.4.25, 4.1.99.12 - H ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HMIFHPHL_01147 1.05e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HMIFHPHL_01148 2.9e-125 - - - S ko:K09962 - ko00000 Nucleotidyltransferase
HMIFHPHL_01149 3.39e-138 - - - - - - - -
HMIFHPHL_01150 3.3e-151 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
HMIFHPHL_01151 5.71e-145 - - - K - - - Bacterial regulatory proteins, tetR family
HMIFHPHL_01152 8.6e-308 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
HMIFHPHL_01153 0.0 - - - - - - - -
HMIFHPHL_01154 4.75e-80 - - - - - - - -
HMIFHPHL_01155 3.36e-248 - - - S - - - Fn3-like domain
HMIFHPHL_01156 2.82e-138 - - - S - - - WxL domain surface cell wall-binding
HMIFHPHL_01157 5.76e-135 - - - S - - - WxL domain surface cell wall-binding
HMIFHPHL_01158 1.09e-196 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HMIFHPHL_01159 6.76e-73 - - - - - - - -
HMIFHPHL_01160 3.6e-106 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
HMIFHPHL_01161 4.47e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_01162 1.11e-282 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HMIFHPHL_01163 7.24e-197 ytmP - - M - - - Choline/ethanolamine kinase
HMIFHPHL_01164 2.8e-155 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HMIFHPHL_01165 2.94e-71 ytzB - - S - - - Peptidase propeptide and YPEB domain
HMIFHPHL_01166 1.45e-145 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMIFHPHL_01167 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HMIFHPHL_01168 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HMIFHPHL_01169 3.04e-29 - - - S - - - Virus attachment protein p12 family
HMIFHPHL_01170 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
HMIFHPHL_01171 5.8e-47 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
HMIFHPHL_01172 1.1e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
HMIFHPHL_01173 5.21e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
HMIFHPHL_01174 6.39e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HMIFHPHL_01175 2.71e-108 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
HMIFHPHL_01176 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
HMIFHPHL_01177 7.63e-249 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HMIFHPHL_01178 4.63e-177 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HMIFHPHL_01179 4.07e-78 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMIFHPHL_01180 1.13e-108 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMIFHPHL_01181 9.53e-107 - - - C - - - Flavodoxin
HMIFHPHL_01182 6.26e-92 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
HMIFHPHL_01183 5.33e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
HMIFHPHL_01184 3.92e-248 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HMIFHPHL_01185 1.98e-278 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Transporter, major facilitator family protein
HMIFHPHL_01186 4.08e-78 - - - S - - - Iron-sulfur cluster assembly protein
HMIFHPHL_01187 7.79e-203 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HMIFHPHL_01188 1.31e-62 - - - H - - - geranyltranstransferase activity
HMIFHPHL_01189 5.52e-111 - - - H - - - geranyltranstransferase activity
HMIFHPHL_01190 6.4e-235 - - - - - - - -
HMIFHPHL_01191 3.67e-65 - - - - - - - -
HMIFHPHL_01192 1.83e-150 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
HMIFHPHL_01193 2.15e-220 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
HMIFHPHL_01194 1.48e-98 - 2.7.13.3 - T ko:K07683,ko:K10851 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 phosphoenolpyruvate-protein phosphotransferase activity
HMIFHPHL_01195 8.84e-52 - - - - - - - -
HMIFHPHL_01196 2.33e-128 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HMIFHPHL_01197 1.08e-111 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HMIFHPHL_01198 2.87e-117 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
HMIFHPHL_01199 2.21e-295 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
HMIFHPHL_01200 1.34e-108 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
HMIFHPHL_01201 1.12e-244 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
HMIFHPHL_01202 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HMIFHPHL_01203 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
HMIFHPHL_01204 8.2e-127 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 Nitrate reductase delta subunit
HMIFHPHL_01205 2.69e-158 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
HMIFHPHL_01206 4.78e-223 - - - - - - - -
HMIFHPHL_01207 4.4e-97 - - - - - - - -
HMIFHPHL_01208 4.4e-126 - - - S - - - Protein of unknown function (DUF2975)
HMIFHPHL_01209 6.66e-39 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HMIFHPHL_01210 8.51e-155 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HMIFHPHL_01211 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMIFHPHL_01212 3.19e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HMIFHPHL_01213 9.54e-134 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMIFHPHL_01214 1.58e-117 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMIFHPHL_01215 1.78e-316 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
HMIFHPHL_01216 6.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HMIFHPHL_01217 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMIFHPHL_01218 2.37e-109 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HMIFHPHL_01219 6.92e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HMIFHPHL_01220 6.88e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMIFHPHL_01221 4.59e-73 - - - - - - - -
HMIFHPHL_01222 7.03e-307 - - - L ko:K07478 - ko00000 AAA C-terminal domain
HMIFHPHL_01223 5.83e-251 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HMIFHPHL_01224 1.64e-83 ydeP - - K - - - Transcriptional regulator, HxlR family
HMIFHPHL_01225 2.39e-175 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HMIFHPHL_01226 9.51e-317 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
HMIFHPHL_01227 1.49e-112 - - - - - - - -
HMIFHPHL_01228 5.7e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
HMIFHPHL_01229 8.98e-275 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
HMIFHPHL_01230 2.19e-67 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
HMIFHPHL_01231 4.19e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMIFHPHL_01232 1.71e-149 yqeK - - H - - - Hydrolase, HD family
HMIFHPHL_01233 1.06e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMIFHPHL_01234 3.3e-180 yqeM - - Q - - - Methyltransferase
HMIFHPHL_01235 2.5e-279 ylbM - - S - - - Belongs to the UPF0348 family
HMIFHPHL_01236 3.66e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HMIFHPHL_01237 1.19e-121 - - - S - - - Peptidase propeptide and YPEB domain
HMIFHPHL_01238 3.12e-168 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMIFHPHL_01239 2.25e-41 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMIFHPHL_01240 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HMIFHPHL_01241 3.12e-311 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HMIFHPHL_01242 1.38e-155 csrR - - K - - - response regulator
HMIFHPHL_01243 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMIFHPHL_01244 1.93e-218 ubiA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HMIFHPHL_01245 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
HMIFHPHL_01246 9.59e-289 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HMIFHPHL_01247 5.08e-122 - - - S - - - SdpI/YhfL protein family
HMIFHPHL_01248 8.09e-208 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMIFHPHL_01249 2.36e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HMIFHPHL_01250 4.46e-179 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMIFHPHL_01251 1.72e-120 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HMIFHPHL_01252 1.09e-83 yodB - - K - - - Transcriptional regulator, HxlR family
HMIFHPHL_01253 2.8e-256 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HMIFHPHL_01254 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMIFHPHL_01255 6.11e-249 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HMIFHPHL_01256 7.5e-146 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HMIFHPHL_01257 1.09e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMIFHPHL_01258 1.32e-143 - - - S - - - membrane
HMIFHPHL_01259 5.72e-99 - - - K - - - LytTr DNA-binding domain
HMIFHPHL_01260 6.12e-72 yneR - - S - - - Belongs to the HesB IscA family
HMIFHPHL_01261 0.0 - - - S - - - membrane
HMIFHPHL_01262 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HMIFHPHL_01263 5.33e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HMIFHPHL_01264 2.67e-131 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HMIFHPHL_01265 3.52e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
HMIFHPHL_01266 6.33e-46 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
HMIFHPHL_01267 2.6e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HMIFHPHL_01268 1.62e-141 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
HMIFHPHL_01269 6.68e-89 yqhL - - P - - - Rhodanese-like protein
HMIFHPHL_01270 1.44e-31 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
HMIFHPHL_01271 6.38e-178 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
HMIFHPHL_01272 6.58e-225 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMIFHPHL_01273 7.79e-85 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
HMIFHPHL_01274 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HMIFHPHL_01275 2.07e-204 - - - - - - - -
HMIFHPHL_01276 3.16e-231 - - - - - - - -
HMIFHPHL_01277 2.92e-126 - - - S - - - Protein conserved in bacteria
HMIFHPHL_01278 1.27e-72 - - - - - - - -
HMIFHPHL_01279 2.97e-41 - - - - - - - -
HMIFHPHL_01282 9.81e-27 - - - - - - - -
HMIFHPHL_01283 8.15e-125 - - - K - - - Transcriptional regulator
HMIFHPHL_01284 1.55e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HMIFHPHL_01285 7.97e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
HMIFHPHL_01286 2.33e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HMIFHPHL_01287 6.04e-249 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HMIFHPHL_01288 1.43e-129 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMIFHPHL_01289 1.7e-96 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
HMIFHPHL_01290 9.43e-90 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMIFHPHL_01291 4.82e-194 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMIFHPHL_01292 2.81e-313 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMIFHPHL_01293 7.55e-44 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMIFHPHL_01294 6.68e-206 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HMIFHPHL_01295 4.49e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HMIFHPHL_01296 5.28e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HMIFHPHL_01297 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HMIFHPHL_01298 4.51e-284 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_01299 7.11e-135 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HMIFHPHL_01300 3.8e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HMIFHPHL_01301 1.36e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMIFHPHL_01302 8.28e-73 - - - - - - - -
HMIFHPHL_01303 6.96e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HMIFHPHL_01304 3.93e-41 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HMIFHPHL_01305 5.04e-278 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HMIFHPHL_01306 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMIFHPHL_01307 3.51e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMIFHPHL_01308 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HMIFHPHL_01309 1.62e-173 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HMIFHPHL_01310 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HMIFHPHL_01311 1.71e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMIFHPHL_01312 2.22e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HMIFHPHL_01313 2.61e-160 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HMIFHPHL_01314 1.61e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HMIFHPHL_01315 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
HMIFHPHL_01316 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
HMIFHPHL_01317 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HMIFHPHL_01318 2.17e-244 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HMIFHPHL_01319 3.33e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMIFHPHL_01320 4.49e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMIFHPHL_01321 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HMIFHPHL_01322 3.47e-294 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HMIFHPHL_01323 1.46e-77 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HMIFHPHL_01324 9.38e-301 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMIFHPHL_01325 1.6e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HMIFHPHL_01326 9.99e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HMIFHPHL_01327 1.29e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HMIFHPHL_01328 4.49e-179 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HMIFHPHL_01329 3.15e-78 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMIFHPHL_01330 1.03e-66 - - - - - - - -
HMIFHPHL_01331 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
HMIFHPHL_01332 4.49e-112 - - - - - - - -
HMIFHPHL_01333 1.32e-77 - - - K - - - Bacterial regulatory proteins, tetR family
HMIFHPHL_01334 5.35e-153 - - - C - - - nadph quinone reductase
HMIFHPHL_01335 2.33e-72 - - - K - - - transcriptional regulator (AraC family)
HMIFHPHL_01336 8.44e-144 - - - G - - - Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HMIFHPHL_01337 6.44e-81 - - - G - - - Bacterial alpha-L-rhamnosidase C-terminal domain
HMIFHPHL_01338 9.82e-136 gph - - G ko:K03292 - ko00000 transporter
HMIFHPHL_01339 4.17e-86 - - - GK - - - ROK family
HMIFHPHL_01340 1.43e-178 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
HMIFHPHL_01341 5.4e-175 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HMIFHPHL_01342 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
HMIFHPHL_01344 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I, N terminal region
HMIFHPHL_01345 8.08e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Peptidase C26
HMIFHPHL_01346 1.42e-224 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HMIFHPHL_01347 5.93e-166 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
HMIFHPHL_01348 1.57e-142 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
HMIFHPHL_01349 3.77e-289 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HMIFHPHL_01350 2.79e-182 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HMIFHPHL_01351 1.45e-126 entB - - Q - - - Isochorismatase family
HMIFHPHL_01352 2.9e-226 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
HMIFHPHL_01353 1.95e-88 ybbJ - - K - - - Acetyltransferase (GNAT) family
HMIFHPHL_01354 1.62e-276 - - - E - - - glutamate:sodium symporter activity
HMIFHPHL_01355 3.38e-274 hipO1 - - E ko:K21613 - ko00000,ko01000,ko01002 Peptidase family M20/M25/M40
HMIFHPHL_01356 2.3e-253 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HMIFHPHL_01357 1.49e-77 - - - S - - - Protein of unknown function (DUF1648)
HMIFHPHL_01359 2.79e-185 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HMIFHPHL_01360 3.65e-226 yneE - - K - - - Transcriptional regulator
HMIFHPHL_01361 8.55e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HMIFHPHL_01362 8.02e-230 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMIFHPHL_01363 1.06e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMIFHPHL_01364 8.52e-216 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
HMIFHPHL_01365 5.14e-162 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HMIFHPHL_01366 1.8e-288 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HMIFHPHL_01367 2.14e-95 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HMIFHPHL_01368 1.71e-91 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
HMIFHPHL_01369 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
HMIFHPHL_01370 3.72e-202 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HMIFHPHL_01371 4.82e-179 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
HMIFHPHL_01372 2.29e-175 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HMIFHPHL_01373 1.18e-127 - - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
HMIFHPHL_01374 1.48e-161 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HMIFHPHL_01375 3.73e-207 - - - K - - - LysR substrate binding domain
HMIFHPHL_01376 5.77e-113 ykhA - - I - - - Thioesterase superfamily
HMIFHPHL_01377 5.36e-247 rsgA_2 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMIFHPHL_01378 1.49e-121 - - - K - - - transcriptional regulator
HMIFHPHL_01379 0.0 - - - EGP - - - Major Facilitator
HMIFHPHL_01380 1.14e-193 - - - O - - - Band 7 protein
HMIFHPHL_01381 8.14e-47 - - - L - - - Pfam:Integrase_AP2
HMIFHPHL_01385 1.19e-13 - - - - - - - -
HMIFHPHL_01387 6.04e-71 - - - - - - - -
HMIFHPHL_01388 2.02e-39 - - - - - - - -
HMIFHPHL_01389 8e-275 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HMIFHPHL_01390 9.96e-147 - 1.14.99.53 AA10 S ko:K21713 - ko00000,ko01000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
HMIFHPHL_01391 7.75e-65 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
HMIFHPHL_01392 1.19e-54 - - - - - - - -
HMIFHPHL_01393 6.05e-108 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
HMIFHPHL_01394 4.34e-99 - - - T - - - Belongs to the universal stress protein A family
HMIFHPHL_01395 3.92e-87 - - - S - - - Protein of unknown function (DUF805)
HMIFHPHL_01396 1.03e-210 - - - I - - - Diacylglycerol kinase catalytic domain
HMIFHPHL_01397 1.51e-48 - - - - - - - -
HMIFHPHL_01398 5.79e-21 - - - - - - - -
HMIFHPHL_01399 2.1e-22 - - - S - - - transglycosylase associated protein
HMIFHPHL_01400 4e-40 - - - S - - - CsbD-like
HMIFHPHL_01401 1.06e-53 - - - - - - - -
HMIFHPHL_01402 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HMIFHPHL_01403 8.39e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
HMIFHPHL_01404 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HMIFHPHL_01405 1.04e-218 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
HMIFHPHL_01406 5.03e-182 - - - U ko:K10716 - ko00000,ko02000 Ion channel
HMIFHPHL_01407 1.52e-67 - - - - - - - -
HMIFHPHL_01408 3.23e-58 - - - - - - - -
HMIFHPHL_01409 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HMIFHPHL_01410 0.0 - - - E ko:K03294 - ko00000 Amino Acid
HMIFHPHL_01411 3.86e-192 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HMIFHPHL_01412 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
HMIFHPHL_01413 2.07e-151 - - - S - - - Domain of unknown function (DUF4767)
HMIFHPHL_01414 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HMIFHPHL_01415 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HMIFHPHL_01416 3.36e-247 galM2 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HMIFHPHL_01417 8.61e-251 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HMIFHPHL_01418 1.77e-262 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
HMIFHPHL_01419 1.1e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
HMIFHPHL_01420 2.1e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
HMIFHPHL_01421 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HMIFHPHL_01422 2.53e-107 ypmB - - S - - - protein conserved in bacteria
HMIFHPHL_01423 2.55e-288 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HMIFHPHL_01424 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HMIFHPHL_01425 1.13e-165 dnaD - - L ko:K02086 - ko00000 Replication initiation and membrane attachment
HMIFHPHL_01427 7.74e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMIFHPHL_01428 1.41e-141 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HMIFHPHL_01429 2.15e-201 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HMIFHPHL_01430 1.31e-109 - - - T - - - Universal stress protein family
HMIFHPHL_01431 0.0 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMIFHPHL_01432 4.66e-233 ftpB - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HMIFHPHL_01433 8.03e-229 phnT 3.6.3.30 - P ko:K02010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HMIFHPHL_01434 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
HMIFHPHL_01435 3.6e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HMIFHPHL_01436 2.12e-142 ypsA - - S - - - Belongs to the UPF0398 family
HMIFHPHL_01437 9.98e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HMIFHPHL_01439 4.11e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HMIFHPHL_01440 1.26e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HMIFHPHL_01441 1.96e-177 - - - P - - - Major Facilitator Superfamily
HMIFHPHL_01442 8.93e-115 - - - P - - - Major Facilitator Superfamily
HMIFHPHL_01443 4.17e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HMIFHPHL_01444 3.2e-95 - - - S - - - SnoaL-like domain
HMIFHPHL_01445 5.32e-49 - - - M - - - Glycosyltransferase, group 2 family protein
HMIFHPHL_01446 2.07e-229 - - - M - - - Glycosyltransferase, group 2 family protein
HMIFHPHL_01447 9.4e-33 mccF - - V - - - LD-carboxypeptidase
HMIFHPHL_01448 4.02e-216 mccF - - V - - - LD-carboxypeptidase
HMIFHPHL_01449 1.66e-101 - - - K - - - Acetyltransferase (GNAT) domain
HMIFHPHL_01450 2.13e-312 - - - M ko:K07273 - ko00000 hydrolase, family 25
HMIFHPHL_01451 2.38e-233 - - - V - - - LD-carboxypeptidase
HMIFHPHL_01452 1.71e-160 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
HMIFHPHL_01453 4.65e-157 - - - P ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HMIFHPHL_01454 9.84e-212 - - - - - - - -
HMIFHPHL_01455 3.69e-187 - - - S - - - hydrolase activity, acting on ester bonds
HMIFHPHL_01456 2.44e-267 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
HMIFHPHL_01457 4.66e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
HMIFHPHL_01458 5.89e-81 esbA - - S - - - Family of unknown function (DUF5322)
HMIFHPHL_01459 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HMIFHPHL_01460 1.65e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HMIFHPHL_01461 9.72e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HMIFHPHL_01462 1.9e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMIFHPHL_01463 1.71e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
HMIFHPHL_01464 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HMIFHPHL_01465 0.0 - - - S - - - Bacterial membrane protein, YfhO
HMIFHPHL_01466 2.01e-145 - - - G - - - Phosphoglycerate mutase family
HMIFHPHL_01467 7.89e-43 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
HMIFHPHL_01469 2.24e-167 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
HMIFHPHL_01470 2.08e-92 - - - S - - - LuxR family transcriptional regulator
HMIFHPHL_01471 3.42e-176 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
HMIFHPHL_01473 3.78e-117 - - - F - - - NUDIX domain
HMIFHPHL_01474 1.74e-179 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_01475 6.28e-48 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HMIFHPHL_01476 6.36e-99 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HMIFHPHL_01477 0.0 FbpA - - K - - - Fibronectin-binding protein
HMIFHPHL_01478 1.97e-87 - - - K - - - Transcriptional regulator
HMIFHPHL_01479 1.11e-205 - - - S - - - EDD domain protein, DegV family
HMIFHPHL_01480 1.43e-100 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
HMIFHPHL_01481 8.31e-170 - - - S - - - Protein of unknown function (DUF975)
HMIFHPHL_01482 4.74e-39 - - - - - - - -
HMIFHPHL_01483 2.37e-65 - - - - - - - -
HMIFHPHL_01484 4.87e-191 - - - C - - - Domain of unknown function (DUF4931)
HMIFHPHL_01485 3.04e-261 pmrB - - EGP - - - Major Facilitator Superfamily
HMIFHPHL_01487 1.33e-67 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
HMIFHPHL_01488 9.3e-167 yejC - - S - - - Protein of unknown function (DUF1003)
HMIFHPHL_01489 2.59e-177 XK27_00890 - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
HMIFHPHL_01490 1.23e-311 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HMIFHPHL_01491 3.9e-176 - - - - - - - -
HMIFHPHL_01492 7.79e-78 - - - - - - - -
HMIFHPHL_01493 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HMIFHPHL_01494 2.25e-288 - - - - - - - -
HMIFHPHL_01495 7.15e-165 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HMIFHPHL_01496 1.47e-243 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HMIFHPHL_01497 1.66e-249 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - H ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMIFHPHL_01498 0.0 tarL 2.7.8.14, 2.7.8.47 - H ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMIFHPHL_01499 1.47e-117 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HMIFHPHL_01500 1.6e-93 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HMIFHPHL_01501 2.27e-304 gshR1 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HMIFHPHL_01502 1.98e-66 - - - - - - - -
HMIFHPHL_01503 4.3e-313 - - - M - - - Glycosyl transferase family group 2
HMIFHPHL_01504 1.64e-153 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMIFHPHL_01505 1.39e-174 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMIFHPHL_01506 5.95e-203 - - - L - - - Phage integrase, N-terminal SAM-like domain
HMIFHPHL_01507 1.07e-43 - - - S - - - YozE SAM-like fold
HMIFHPHL_01508 9.17e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMIFHPHL_01509 3.8e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HMIFHPHL_01510 3.21e-215 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
HMIFHPHL_01511 1.56e-227 - - - K - - - Transcriptional regulator
HMIFHPHL_01512 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMIFHPHL_01513 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMIFHPHL_01514 9.76e-137 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HMIFHPHL_01515 1.27e-217 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HMIFHPHL_01516 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HMIFHPHL_01517 6.84e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HMIFHPHL_01518 1.5e-227 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
HMIFHPHL_01519 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HMIFHPHL_01520 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMIFHPHL_01521 8.11e-203 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
HMIFHPHL_01522 5e-176 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMIFHPHL_01523 2.25e-207 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HMIFHPHL_01525 5.13e-292 XK27_05470 - - E - - - Methionine synthase
HMIFHPHL_01526 1.22e-219 cpsY - - K - - - Transcriptional regulator, LysR family
HMIFHPHL_01527 5.18e-222 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
HMIFHPHL_01528 5.85e-159 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HMIFHPHL_01529 4.28e-253 XK27_00915 - - C - - - Luciferase-like monooxygenase
HMIFHPHL_01530 0.0 qacA - - EGP - - - Major Facilitator
HMIFHPHL_01531 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HMIFHPHL_01532 9.33e-48 yozE - - S - - - Belongs to the UPF0346 family
HMIFHPHL_01533 9.42e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
HMIFHPHL_01534 8.39e-209 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
HMIFHPHL_01535 2.03e-189 WQ51_01275 - - S - - - EDD domain protein, DegV family
HMIFHPHL_01536 1.8e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HMIFHPHL_01537 4.04e-242 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HMIFHPHL_01538 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_01539 6.46e-109 - - - - - - - -
HMIFHPHL_01540 8.58e-290 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HMIFHPHL_01541 5.66e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HMIFHPHL_01542 1.29e-192 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HMIFHPHL_01543 7.1e-292 XK27_05225 - - S - - - Tetratricopeptide repeat protein
HMIFHPHL_01544 5.57e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMIFHPHL_01545 2.06e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HMIFHPHL_01546 1.98e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HMIFHPHL_01547 1.27e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HMIFHPHL_01548 2.82e-38 - - - M - - - Lysin motif
HMIFHPHL_01549 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HMIFHPHL_01550 3.38e-252 - - - S - - - Helix-turn-helix domain
HMIFHPHL_01551 2.24e-126 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HMIFHPHL_01552 2.69e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HMIFHPHL_01553 1.3e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HMIFHPHL_01554 7.1e-176 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMIFHPHL_01555 3.99e-92 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMIFHPHL_01556 3.13e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
HMIFHPHL_01557 7.94e-218 yitL - - S ko:K00243 - ko00000 S1 domain
HMIFHPHL_01558 2.51e-98 ytwI - - S - - - Protein of unknown function (DUF441)
HMIFHPHL_01559 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HMIFHPHL_01560 8.69e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HMIFHPHL_01561 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HMIFHPHL_01562 2.02e-39 - - - S - - - Protein of unknown function (DUF2929)
HMIFHPHL_01563 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMIFHPHL_01564 3.7e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HMIFHPHL_01565 1.61e-251 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HMIFHPHL_01566 8.34e-165 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HMIFHPHL_01567 5.84e-294 - - - M - - - O-Antigen ligase
HMIFHPHL_01568 8.81e-166 drrB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
HMIFHPHL_01569 3.85e-209 drrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HMIFHPHL_01570 2.74e-112 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HMIFHPHL_01571 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HMIFHPHL_01572 1.59e-60 - - - P - - - Rhodanese Homology Domain
HMIFHPHL_01573 7.43e-119 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
HMIFHPHL_01574 5.78e-268 - - - - - - - -
HMIFHPHL_01575 6.09e-281 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
HMIFHPHL_01576 1.51e-232 - - - C - - - Zinc-binding dehydrogenase
HMIFHPHL_01577 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
HMIFHPHL_01578 5.18e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMIFHPHL_01579 4.6e-307 - - - U ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
HMIFHPHL_01580 4.38e-102 - - - K - - - Transcriptional regulator
HMIFHPHL_01581 3.34e-267 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HMIFHPHL_01582 0.0 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HMIFHPHL_01583 5.87e-177 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
HMIFHPHL_01584 9.89e-138 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
HMIFHPHL_01585 1.08e-92 spx2 - - P ko:K16509 - ko00000 ArsC family
HMIFHPHL_01586 1.56e-90 - - - S - - - Protein of unknown function (DUF1722)
HMIFHPHL_01587 5.7e-146 - - - GM - - - epimerase
HMIFHPHL_01588 0.0 - - - S - - - Zinc finger, swim domain protein
HMIFHPHL_01589 6.13e-105 - - - K - - - Bacterial regulatory proteins, tetR family
HMIFHPHL_01590 1.86e-272 - - - S - - - membrane
HMIFHPHL_01591 2.15e-07 - - - K - - - transcriptional regulator
HMIFHPHL_01592 4.05e-90 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HMIFHPHL_01593 6.03e-36 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMIFHPHL_01594 7.51e-147 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
HMIFHPHL_01595 2.31e-132 thgA3 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
HMIFHPHL_01596 2.49e-167 - - - K - - - Helix-turn-helix domain, rpiR family
HMIFHPHL_01597 9.18e-207 - - - S - - - Alpha beta hydrolase
HMIFHPHL_01598 4.32e-147 - - - GM - - - NmrA-like family
HMIFHPHL_01599 2.12e-102 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
HMIFHPHL_01600 5.72e-207 - - - K - - - Transcriptional regulator
HMIFHPHL_01601 3.78e-221 cryZ 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
HMIFHPHL_01603 0.0 nox4 - - C - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HMIFHPHL_01604 1.11e-134 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
HMIFHPHL_01605 4.7e-262 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMIFHPHL_01606 7.05e-172 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
HMIFHPHL_01607 4.17e-204 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HMIFHPHL_01609 6.64e-109 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HMIFHPHL_01610 4.73e-95 - - - K - - - MarR family
HMIFHPHL_01611 1.28e-148 - - - S - - - Psort location CytoplasmicMembrane, score
HMIFHPHL_01612 0.000138 yjdF - - S - - - Protein of unknown function (DUF2992)
HMIFHPHL_01613 4.36e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_01614 2.02e-168 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HMIFHPHL_01615 6.08e-253 - - - - - - - -
HMIFHPHL_01616 5.23e-256 - - - - - - - -
HMIFHPHL_01617 2.45e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_01618 6.86e-85 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HMIFHPHL_01619 1.74e-251 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMIFHPHL_01620 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HMIFHPHL_01621 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HMIFHPHL_01622 8.64e-224 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HMIFHPHL_01623 2.84e-189 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HMIFHPHL_01624 7.92e-217 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HMIFHPHL_01625 1.15e-94 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HMIFHPHL_01626 1.81e-108 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMIFHPHL_01627 4.81e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
HMIFHPHL_01628 9.21e-94 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
HMIFHPHL_01629 1.09e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HMIFHPHL_01630 2.32e-194 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HMIFHPHL_01631 3.65e-166 - - - C - - - Enoyl-(Acyl carrier protein) reductase
HMIFHPHL_01632 5.8e-217 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HMIFHPHL_01633 4.51e-285 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMIFHPHL_01634 4.35e-204 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMIFHPHL_01635 2.61e-132 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMIFHPHL_01636 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HMIFHPHL_01637 2.47e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HMIFHPHL_01638 2.83e-200 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
HMIFHPHL_01639 1.79e-211 - - - G - - - Fructosamine kinase
HMIFHPHL_01640 5.97e-151 yjcF - - J - - - HAD-hyrolase-like
HMIFHPHL_01641 8.2e-102 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HMIFHPHL_01642 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMIFHPHL_01643 2.56e-76 - - - - - - - -
HMIFHPHL_01644 7.36e-171 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HMIFHPHL_01645 2.04e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
HMIFHPHL_01646 1.35e-148 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HMIFHPHL_01647 4.78e-65 - - - - - - - -
HMIFHPHL_01648 1.73e-67 - - - - - - - -
HMIFHPHL_01649 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMIFHPHL_01650 1.68e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HMIFHPHL_01651 5.75e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMIFHPHL_01652 6.6e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
HMIFHPHL_01653 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMIFHPHL_01654 8.59e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
HMIFHPHL_01655 8.49e-266 pbpX2 - - V - - - Beta-lactamase
HMIFHPHL_01656 2.54e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HMIFHPHL_01657 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HMIFHPHL_01658 1.72e-115 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMIFHPHL_01659 4.42e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMIFHPHL_01660 2.06e-170 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
HMIFHPHL_01661 6.48e-243 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HMIFHPHL_01662 6.29e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMIFHPHL_01663 3.99e-112 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HMIFHPHL_01664 2.84e-244 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
HMIFHPHL_01665 1.92e-301 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HMIFHPHL_01666 1.63e-121 - - - - - - - -
HMIFHPHL_01667 2.12e-274 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HMIFHPHL_01668 0.0 - - - G - - - Major Facilitator
HMIFHPHL_01669 3.04e-71 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMIFHPHL_01670 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMIFHPHL_01671 3.28e-63 ylxQ - - J - - - ribosomal protein
HMIFHPHL_01672 2.95e-65 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
HMIFHPHL_01673 4.46e-275 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HMIFHPHL_01674 9.74e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HMIFHPHL_01675 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMIFHPHL_01676 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HMIFHPHL_01677 4.64e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HMIFHPHL_01678 1.13e-175 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HMIFHPHL_01679 3.17e-190 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMIFHPHL_01680 9.83e-113 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMIFHPHL_01681 3.01e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HMIFHPHL_01682 1.88e-194 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMIFHPHL_01683 6.33e-185 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HMIFHPHL_01684 2.92e-172 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
HMIFHPHL_01685 1.92e-239 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMIFHPHL_01686 1.69e-65 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
HMIFHPHL_01687 3.13e-173 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
HMIFHPHL_01688 1.71e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
HMIFHPHL_01689 3.96e-44 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
HMIFHPHL_01690 7.68e-48 ynzC - - S - - - UPF0291 protein
HMIFHPHL_01691 7.22e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HMIFHPHL_01692 7.8e-123 - - - - - - - -
HMIFHPHL_01693 1.34e-277 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
HMIFHPHL_01694 1.01e-100 - - - - - - - -
HMIFHPHL_01695 3.81e-87 - - - - - - - -
HMIFHPHL_01696 4.63e-226 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase like family 2
HMIFHPHL_01699 5.32e-12 - - - S - - - Short C-terminal domain
HMIFHPHL_01700 8.66e-21 - - - S - - - Short C-terminal domain
HMIFHPHL_01701 9.99e-05 - - - S - - - Short C-terminal domain
HMIFHPHL_01702 1.51e-53 - - - L - - - HTH-like domain
HMIFHPHL_01703 3.53e-43 - - - L ko:K07483 - ko00000 transposase activity
HMIFHPHL_01704 8.56e-74 - - - S - - - Phage integrase family
HMIFHPHL_01707 1.75e-43 - - - - - - - -
HMIFHPHL_01708 3.41e-182 - - - Q - - - Methyltransferase
HMIFHPHL_01709 2.84e-75 ybjQ - - S - - - Belongs to the UPF0145 family
HMIFHPHL_01710 2.87e-270 - - - EGP - - - Major facilitator Superfamily
HMIFHPHL_01711 4.57e-135 - - - K - - - Helix-turn-helix domain
HMIFHPHL_01712 1.52e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HMIFHPHL_01713 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HMIFHPHL_01714 1.84e-67 - - - S - - - Lipopolysaccharide assembly protein A domain
HMIFHPHL_01715 7.09e-180 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HMIFHPHL_01716 5.87e-228 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HMIFHPHL_01717 6.62e-62 - - - - - - - -
HMIFHPHL_01718 5.19e-310 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMIFHPHL_01719 3.02e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
HMIFHPHL_01720 2.99e-218 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HMIFHPHL_01721 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
HMIFHPHL_01722 0.0 - 3.1.4.53 - S ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
HMIFHPHL_01723 1.74e-298 cps4J - - S - - - MatE
HMIFHPHL_01724 1.38e-227 cps4I - - M - - - Glycosyltransferase like family 2
HMIFHPHL_01725 1.23e-293 - - - - - - - -
HMIFHPHL_01726 9.67e-229 cps4G - - M - - - Glycosyltransferase Family 4
HMIFHPHL_01727 2.65e-248 cps4F - - M - - - Glycosyl transferases group 1
HMIFHPHL_01728 3.86e-163 tuaA - - M - - - Bacterial sugar transferase
HMIFHPHL_01729 8.35e-229 cps4D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
HMIFHPHL_01730 5.54e-189 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HMIFHPHL_01731 4.97e-157 ywqD - - D - - - Capsular exopolysaccharide family
HMIFHPHL_01732 8.45e-162 epsB - - M - - - biosynthesis protein
HMIFHPHL_01733 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMIFHPHL_01734 3.97e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_01735 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HMIFHPHL_01736 5.12e-31 - - - - - - - -
HMIFHPHL_01737 6.47e-95 - - - S - - - Iron-sulphur cluster biosynthesis
HMIFHPHL_01738 4.41e-59 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HMIFHPHL_01739 1.3e-65 - - - S - - - mazG nucleotide pyrophosphohydrolase
HMIFHPHL_01740 9.6e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HMIFHPHL_01741 7.8e-300 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMIFHPHL_01742 3.21e-288 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMIFHPHL_01743 4.38e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMIFHPHL_01744 9.34e-201 - - - S - - - Tetratricopeptide repeat
HMIFHPHL_01745 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMIFHPHL_01746 1.29e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMIFHPHL_01747 3.15e-261 - - - EGP - - - Major Facilitator Superfamily
HMIFHPHL_01748 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HMIFHPHL_01749 1.18e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HMIFHPHL_01750 2.07e-240 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HMIFHPHL_01751 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HMIFHPHL_01752 7.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HMIFHPHL_01753 5.47e-157 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
HMIFHPHL_01754 1.05e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HMIFHPHL_01755 2.99e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMIFHPHL_01756 9.66e-129 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
HMIFHPHL_01757 1.91e-66 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
HMIFHPHL_01758 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HMIFHPHL_01759 2.06e-260 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HMIFHPHL_01760 0.0 - - - - - - - -
HMIFHPHL_01761 0.0 icaA - - M - - - Glycosyl transferase family group 2
HMIFHPHL_01762 9.51e-135 - - - - - - - -
HMIFHPHL_01763 6.8e-69 - - - - - - - -
HMIFHPHL_01764 1.4e-173 - - - - - - - -
HMIFHPHL_01765 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HMIFHPHL_01766 1.23e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
HMIFHPHL_01767 2.64e-62 yktA - - S - - - Belongs to the UPF0223 family
HMIFHPHL_01768 5.06e-208 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
HMIFHPHL_01769 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
HMIFHPHL_01770 2.36e-285 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HMIFHPHL_01771 6.35e-230 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
HMIFHPHL_01772 7.02e-268 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
HMIFHPHL_01773 3.95e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMIFHPHL_01774 6.45e-111 - - - - - - - -
HMIFHPHL_01775 4.86e-45 ykzG - - S - - - Belongs to the UPF0356 family
HMIFHPHL_01776 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMIFHPHL_01777 1.2e-240 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HMIFHPHL_01778 2.16e-39 - - - - - - - -
HMIFHPHL_01779 2.62e-168 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
HMIFHPHL_01780 5.35e-220 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMIFHPHL_01781 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HMIFHPHL_01782 1.02e-155 - - - S - - - repeat protein
HMIFHPHL_01783 2.41e-157 pgm6 - - G - - - phosphoglycerate mutase
HMIFHPHL_01784 0.0 - - - N - - - domain, Protein
HMIFHPHL_01785 2.75e-243 - - - S - - - Bacterial protein of unknown function (DUF916)
HMIFHPHL_01786 4.17e-153 - - - N - - - WxL domain surface cell wall-binding
HMIFHPHL_01787 4.64e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
HMIFHPHL_01788 9.64e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
HMIFHPHL_01789 6.7e-285 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HMIFHPHL_01790 2.86e-74 XK27_04120 - - S - - - Putative amino acid metabolism
HMIFHPHL_01791 3.69e-278 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HMIFHPHL_01792 5.85e-158 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HMIFHPHL_01793 7.74e-47 - - - - - - - -
HMIFHPHL_01794 1.43e-124 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HMIFHPHL_01795 3.46e-242 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HMIFHPHL_01796 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMIFHPHL_01797 6.52e-124 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
HMIFHPHL_01798 1.19e-186 ylmH - - S - - - S4 domain protein
HMIFHPHL_01799 6.45e-49 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
HMIFHPHL_01800 1.56e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HMIFHPHL_01801 9.39e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMIFHPHL_01802 1.18e-310 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HMIFHPHL_01803 2.34e-208 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HMIFHPHL_01804 1.43e-252 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMIFHPHL_01805 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMIFHPHL_01806 2.81e-231 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMIFHPHL_01807 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HMIFHPHL_01808 7.01e-76 ftsL - - D - - - Cell division protein FtsL
HMIFHPHL_01809 2.12e-225 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMIFHPHL_01810 7.24e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HMIFHPHL_01811 3.22e-82 - - - S - - - Protein of unknown function (DUF3397)
HMIFHPHL_01812 1.43e-223 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HMIFHPHL_01813 2.69e-226 - - - L ko:K07482 - ko00000 Integrase core domain
HMIFHPHL_01814 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HMIFHPHL_01815 2.02e-123 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMIFHPHL_01816 1.76e-147 - - - S ko:K07118 - ko00000 NAD(P)H-binding
HMIFHPHL_01817 6.93e-299 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HMIFHPHL_01818 2.64e-39 - 3.4.15.6 - E ko:K13282 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
HMIFHPHL_01819 1.12e-207 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
HMIFHPHL_01820 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMIFHPHL_01821 9.52e-264 XK27_05220 - - S - - - AI-2E family transporter
HMIFHPHL_01822 2.68e-75 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
HMIFHPHL_01823 1.6e-246 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HMIFHPHL_01824 7.21e-150 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
HMIFHPHL_01825 6.31e-222 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HMIFHPHL_01826 1.29e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMIFHPHL_01827 9.08e-157 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HMIFHPHL_01828 2.24e-148 yjbH - - Q - - - Thioredoxin
HMIFHPHL_01829 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HMIFHPHL_01830 3.19e-264 coiA - - S ko:K06198 - ko00000 Competence protein
HMIFHPHL_01831 1.18e-168 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HMIFHPHL_01832 9.28e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HMIFHPHL_01833 4.66e-177 yhfI - - S - - - Metallo-beta-lactamase superfamily
HMIFHPHL_01834 1.08e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HMIFHPHL_01856 4.51e-84 - - - - - - - -
HMIFHPHL_01857 2e-98 yugI - - J ko:K07570,ko:K07571 - ko00000 general stress protein
HMIFHPHL_01858 5.16e-141 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMIFHPHL_01859 7.18e-153 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
HMIFHPHL_01860 3.3e-151 - - - S - - - Protein of unknown function (DUF1461)
HMIFHPHL_01861 7.18e-189 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HMIFHPHL_01862 1.96e-116 yutD - - S - - - Protein of unknown function (DUF1027)
HMIFHPHL_01863 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HMIFHPHL_01864 1.36e-149 - - - S - - - Calcineurin-like phosphoesterase
HMIFHPHL_01865 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HMIFHPHL_01866 4.7e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMIFHPHL_01867 9.44e-238 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HMIFHPHL_01869 7.53e-112 - - - S - - - Prokaryotic N-terminal methylation motif
HMIFHPHL_01870 3.03e-27 - - - - ko:K02671 - ko00000,ko02035,ko02044 -
HMIFHPHL_01871 1.5e-108 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
HMIFHPHL_01872 1.97e-72 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
HMIFHPHL_01873 6.2e-242 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
HMIFHPHL_01874 8.95e-225 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
HMIFHPHL_01875 2.06e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMIFHPHL_01876 2.21e-168 yebC - - K - - - Transcriptional regulatory protein
HMIFHPHL_01877 1.16e-63 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
HMIFHPHL_01878 7.88e-211 - - - G - - - Xylose isomerase domain protein TIM barrel
HMIFHPHL_01879 5.44e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HMIFHPHL_01880 1.55e-275 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HMIFHPHL_01881 9.11e-106 - - - K - - - helix_turn_helix, mercury resistance
HMIFHPHL_01882 1.04e-07 - - - L ko:K07487 - ko00000 Transposase
HMIFHPHL_01883 1.6e-96 - - - - - - - -
HMIFHPHL_01884 1.88e-75 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HMIFHPHL_01885 2.31e-202 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
HMIFHPHL_01886 6.72e-289 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HMIFHPHL_01887 2.29e-112 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HMIFHPHL_01888 7.94e-114 ykuL - - S - - - (CBS) domain
HMIFHPHL_01889 4.53e-122 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
HMIFHPHL_01890 8.49e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMIFHPHL_01891 8.74e-195 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HMIFHPHL_01892 2.57e-118 yslB - - S - - - Protein of unknown function (DUF2507)
HMIFHPHL_01893 3e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HMIFHPHL_01894 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HMIFHPHL_01895 1.06e-49 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HMIFHPHL_01896 1.31e-63 yrzB - - S - - - Belongs to the UPF0473 family
HMIFHPHL_01897 5.39e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMIFHPHL_01898 5e-57 yrzL - - S - - - Belongs to the UPF0297 family
HMIFHPHL_01899 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMIFHPHL_01900 2.79e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HMIFHPHL_01901 8.32e-227 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
HMIFHPHL_01902 2.04e-275 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMIFHPHL_01903 1.32e-63 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HMIFHPHL_01904 9.91e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HMIFHPHL_01905 5.87e-256 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HMIFHPHL_01906 2.62e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMIFHPHL_01907 2.83e-138 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMIFHPHL_01908 1.25e-119 - - - - - - - -
HMIFHPHL_01909 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HMIFHPHL_01910 5.5e-93 - - - - - - - -
HMIFHPHL_01911 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HMIFHPHL_01912 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HMIFHPHL_01913 6.18e-197 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 YmdB-like protein
HMIFHPHL_01914 6.57e-291 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HMIFHPHL_01915 2.43e-264 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMIFHPHL_01916 6.34e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HMIFHPHL_01917 1.92e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMIFHPHL_01918 8.15e-172 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
HMIFHPHL_01919 0.0 ymfH - - S - - - Peptidase M16
HMIFHPHL_01920 1.44e-295 ymfF - - S - - - Peptidase M16 inactive domain protein
HMIFHPHL_01921 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HMIFHPHL_01922 2.61e-199 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HMIFHPHL_01923 3.17e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_01924 1.89e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HMIFHPHL_01925 1.23e-187 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
HMIFHPHL_01926 3.81e-150 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HMIFHPHL_01927 1.34e-114 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
HMIFHPHL_01928 3.76e-184 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HMIFHPHL_01929 1.74e-211 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
HMIFHPHL_01930 1.15e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
HMIFHPHL_01931 9.36e-317 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HMIFHPHL_01932 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMIFHPHL_01933 5.06e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HMIFHPHL_01934 2.6e-298 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
HMIFHPHL_01935 7.66e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMIFHPHL_01936 8.66e-276 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HMIFHPHL_01937 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HMIFHPHL_01938 5.28e-105 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HMIFHPHL_01939 2.15e-137 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HMIFHPHL_01940 4.02e-145 yktB - - S - - - Belongs to the UPF0637 family
HMIFHPHL_01941 2.82e-105 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
HMIFHPHL_01942 6.4e-142 - - - S - - - Protein of unknown function (DUF1648)
HMIFHPHL_01943 3.19e-59 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HMIFHPHL_01944 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HMIFHPHL_01945 7.27e-303 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HMIFHPHL_01946 1.34e-52 - - - - - - - -
HMIFHPHL_01947 2.37e-107 uspA - - T - - - universal stress protein
HMIFHPHL_01948 6.65e-260 bla2 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HMIFHPHL_01949 4.7e-207 - - - K - - - Helix-turn-helix XRE-family like proteins
HMIFHPHL_01950 0.0 glpQ3 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
HMIFHPHL_01951 6.54e-273 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HMIFHPHL_01952 7.55e-242 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HMIFHPHL_01953 3.26e-227 - - - S - - - Protein of unknown function (DUF2785)
HMIFHPHL_01954 3.34e-215 hicD3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HMIFHPHL_01955 3.03e-191 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HMIFHPHL_01956 2.1e-151 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HMIFHPHL_01957 2.24e-239 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMIFHPHL_01958 3.2e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
HMIFHPHL_01959 8.74e-280 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HMIFHPHL_01960 2.54e-46 - - - S - - - Protein of unknown function (DUF2969)
HMIFHPHL_01961 1.52e-57 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
HMIFHPHL_01962 1.44e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
HMIFHPHL_01963 1.68e-132 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HMIFHPHL_01964 2.94e-315 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMIFHPHL_01965 5.95e-74 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HMIFHPHL_01966 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMIFHPHL_01967 9.14e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMIFHPHL_01968 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMIFHPHL_01969 2.03e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMIFHPHL_01970 5.41e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMIFHPHL_01971 1.81e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMIFHPHL_01972 4.82e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HMIFHPHL_01973 1.44e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
HMIFHPHL_01974 7.81e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HMIFHPHL_01975 5.03e-296 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HMIFHPHL_01976 2.09e-242 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HMIFHPHL_01977 9.87e-204 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMIFHPHL_01978 1.88e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMIFHPHL_01979 1.54e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HMIFHPHL_01980 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
HMIFHPHL_01981 7.16e-173 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
HMIFHPHL_01982 2.87e-249 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HMIFHPHL_01983 4.58e-246 ampC - - V - - - Beta-lactamase
HMIFHPHL_01984 2.46e-40 - - - - - - - -
HMIFHPHL_01985 1.9e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HMIFHPHL_01986 1.33e-77 - - - - - - - -
HMIFHPHL_01987 2.66e-182 - - - - - - - -
HMIFHPHL_01988 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
HMIFHPHL_01989 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_01990 7.39e-85 yxeA - - S - - - Protein of unknown function (DUF1093)
HMIFHPHL_01991 2.96e-182 icaB - - G - - - Polysaccharide deacetylase
HMIFHPHL_01992 6.18e-144 - - - - - - - -
HMIFHPHL_01994 4.73e-61 - - - S - - - Bacteriophage holin
HMIFHPHL_01995 7.86e-65 - - - - - - - -
HMIFHPHL_01996 1.55e-255 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HMIFHPHL_01998 1.58e-95 - - - S - - - Protein of unknown function (DUF1617)
HMIFHPHL_01999 0.0 - - - LM - - - DNA recombination
HMIFHPHL_02000 9.32e-81 - - - - - - - -
HMIFHPHL_02001 0.0 - - - D - - - domain protein
HMIFHPHL_02002 3.76e-32 - - - - - - - -
HMIFHPHL_02003 1.42e-83 - - - - - - - -
HMIFHPHL_02004 7.42e-102 - - - S - - - Phage tail tube protein, TTP
HMIFHPHL_02005 3.49e-72 - - - - - - - -
HMIFHPHL_02006 9.24e-116 - - - - - - - -
HMIFHPHL_02007 9.63e-68 - - - - - - - -
HMIFHPHL_02008 2.9e-68 - - - - - - - -
HMIFHPHL_02010 2.08e-222 - - - S - - - Phage major capsid protein E
HMIFHPHL_02011 2.84e-64 - - - - - - - -
HMIFHPHL_02014 3.05e-41 - - - - - - - -
HMIFHPHL_02015 0.0 - - - S - - - Phage Mu protein F like protein
HMIFHPHL_02016 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
HMIFHPHL_02017 4.38e-306 - - - S - - - Terminase-like family
HMIFHPHL_02018 4.61e-105 - - - L ko:K07474 - ko00000 Terminase small subunit
HMIFHPHL_02019 1.71e-18 - - - - - - - -
HMIFHPHL_02020 6.49e-25 - - - - - - - -
HMIFHPHL_02026 2.51e-105 - - - S - - - Phage transcriptional regulator, ArpU family
HMIFHPHL_02027 9.69e-117 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
HMIFHPHL_02028 4.14e-20 - - - - - - - -
HMIFHPHL_02029 5.7e-87 - - - L - - - Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HMIFHPHL_02030 4.73e-83 - - - - - - - -
HMIFHPHL_02031 1.88e-66 - - - - - - - -
HMIFHPHL_02032 2.09e-212 - - - L - - - DnaD domain protein
HMIFHPHL_02033 5.87e-177 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
HMIFHPHL_02034 7.41e-198 - - - L ko:K07455 - ko00000,ko03400 RecT family
HMIFHPHL_02035 8.69e-92 - - - - - - - -
HMIFHPHL_02037 2.12e-101 - - - - - - - -
HMIFHPHL_02038 1.82e-69 - - - - - - - -
HMIFHPHL_02041 2.62e-08 - - - K - - - Transcriptional regulator, XRE family
HMIFHPHL_02042 1.19e-24 - - - K - - - Cro/C1-type HTH DNA-binding domain
HMIFHPHL_02045 7.19e-51 - - - K - - - Helix-turn-helix
HMIFHPHL_02046 1.32e-80 - - - K - - - Helix-turn-helix domain
HMIFHPHL_02047 7.82e-97 - - - E - - - IrrE N-terminal-like domain
HMIFHPHL_02048 2.29e-92 - - - - - - - -
HMIFHPHL_02050 4.6e-16 - - - M - - - LysM domain
HMIFHPHL_02055 2.78e-48 - - - S - - - Domain of unknown function DUF1829
HMIFHPHL_02056 3.66e-276 int3 - - L - - - Belongs to the 'phage' integrase family
HMIFHPHL_02058 1.15e-39 - - - - - - - -
HMIFHPHL_02060 1.28e-51 - - - - - - - -
HMIFHPHL_02061 1.09e-56 - - - - - - - -
HMIFHPHL_02062 1.05e-108 - - - K - - - MarR family
HMIFHPHL_02063 0.0 - - - D - - - nuclear chromosome segregation
HMIFHPHL_02064 0.0 inlJ - - M - - - MucBP domain
HMIFHPHL_02065 3.26e-24 - - - - - - - -
HMIFHPHL_02066 1.56e-22 - - - - - - - -
HMIFHPHL_02067 1.07e-26 - - - - - - - -
HMIFHPHL_02068 9.35e-24 - - - - - - - -
HMIFHPHL_02069 9.35e-24 - - - - - - - -
HMIFHPHL_02070 9.35e-24 - - - - - - - -
HMIFHPHL_02071 2.16e-26 - - - - - - - -
HMIFHPHL_02072 4.63e-24 - - - - - - - -
HMIFHPHL_02073 0.0 - 3.6.3.44 - P ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter transmembrane region
HMIFHPHL_02074 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HMIFHPHL_02075 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_02076 6.12e-32 - - - - - - - -
HMIFHPHL_02077 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HMIFHPHL_02078 2.51e-200 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
HMIFHPHL_02079 1.83e-277 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
HMIFHPHL_02080 0.0 yclK - - T - - - Histidine kinase
HMIFHPHL_02081 1.45e-173 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
HMIFHPHL_02082 2.12e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
HMIFHPHL_02083 1.06e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
HMIFHPHL_02084 1.8e-218 - - - EG - - - EamA-like transporter family
HMIFHPHL_02086 6.24e-120 - - - S - - - ECF-type riboflavin transporter, S component
HMIFHPHL_02087 1.31e-64 - - - - - - - -
HMIFHPHL_02088 6.83e-274 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
HMIFHPHL_02089 8.05e-178 - - - F - - - NUDIX domain
HMIFHPHL_02090 2.68e-32 - - - - - - - -
HMIFHPHL_02092 2e-207 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HMIFHPHL_02093 1.43e-221 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
HMIFHPHL_02094 5.92e-107 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
HMIFHPHL_02095 2.29e-48 - - - - - - - -
HMIFHPHL_02096 1.11e-45 - - - - - - - -
HMIFHPHL_02097 9.39e-277 - - - T - - - diguanylate cyclase
HMIFHPHL_02098 0.0 - - - S - - - ABC transporter, ATP-binding protein
HMIFHPHL_02099 9.24e-140 - - - K ko:K06977 - ko00000 acetyltransferase
HMIFHPHL_02100 5.76e-107 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMIFHPHL_02101 9.2e-62 - - - - - - - -
HMIFHPHL_02102 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HMIFHPHL_02103 1.31e-242 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMIFHPHL_02104 8.13e-208 - - - S - - - Uncharacterised protein, DegV family COG1307
HMIFHPHL_02105 8.69e-295 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
HMIFHPHL_02106 6.08e-312 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HMIFHPHL_02107 2.18e-213 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
HMIFHPHL_02108 2.29e-225 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HMIFHPHL_02109 6.03e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HMIFHPHL_02110 1.38e-180 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_02111 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
HMIFHPHL_02112 2.34e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
HMIFHPHL_02113 1.01e-176 yceF - - P ko:K05794 - ko00000 membrane
HMIFHPHL_02114 4.99e-125 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HMIFHPHL_02115 3.68e-256 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HMIFHPHL_02116 1.07e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
HMIFHPHL_02117 6.12e-78 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HMIFHPHL_02118 1.27e-172 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HMIFHPHL_02119 6.84e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HMIFHPHL_02120 2.23e-142 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HMIFHPHL_02121 2.46e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
HMIFHPHL_02122 1.92e-299 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HMIFHPHL_02123 1.69e-151 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HMIFHPHL_02124 1.39e-276 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HMIFHPHL_02125 1.12e-208 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
HMIFHPHL_02126 3.05e-282 ysaA - - V - - - RDD family
HMIFHPHL_02127 7.28e-213 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HMIFHPHL_02128 1.71e-67 - - - S - - - Domain of unknown function (DU1801)
HMIFHPHL_02129 2.54e-17 rmeB - - K - - - transcriptional regulator, MerR family
HMIFHPHL_02130 6.86e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMIFHPHL_02131 1.35e-236 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HMIFHPHL_02132 1.45e-46 - - - - - - - -
HMIFHPHL_02133 3.1e-144 - - - S - - - Protein of unknown function (DUF1211)
HMIFHPHL_02134 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
HMIFHPHL_02135 0.0 - - - M - - - domain protein
HMIFHPHL_02136 2.11e-98 yjcF - - S - - - Acetyltransferase (GNAT) domain
HMIFHPHL_02137 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMIFHPHL_02138 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
HMIFHPHL_02139 4.01e-236 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HMIFHPHL_02140 1.68e-180 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HMIFHPHL_02141 2.22e-248 - - - S - - - domain, Protein
HMIFHPHL_02142 7.05e-216 - - - S - - - Polyphosphate kinase 2 (PPK2)
HMIFHPHL_02143 1.05e-127 - - - C - - - Nitroreductase family
HMIFHPHL_02144 1.23e-228 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
HMIFHPHL_02145 1.64e-207 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMIFHPHL_02146 7.45e-196 - - - U ko:K05340 - ko00000,ko02000 sugar transport
HMIFHPHL_02147 2.22e-209 - - - GK - - - ROK family
HMIFHPHL_02148 2.08e-199 - 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMIFHPHL_02149 1.18e-172 rdrA - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
HMIFHPHL_02150 0.0 pflD 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
HMIFHPHL_02151 1.75e-227 - - - K - - - sugar-binding domain protein
HMIFHPHL_02152 1.81e-160 mipB 2.2.1.2 - H ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
HMIFHPHL_02153 2.13e-182 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HMIFHPHL_02154 2.89e-224 ccpB - - K - - - lacI family
HMIFHPHL_02155 4.34e-202 - - - K - - - Helix-turn-helix domain, rpiR family
HMIFHPHL_02156 2.48e-227 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HMIFHPHL_02157 1.49e-251 yhhX - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HMIFHPHL_02158 0.0 nhaP2 - - P ko:K03316 - ko00000 Sodium proton antiporter
HMIFHPHL_02159 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HMIFHPHL_02160 7.71e-138 pncA - - Q - - - Isochorismatase family
HMIFHPHL_02161 3.77e-172 - - - - - - - -
HMIFHPHL_02162 5e-162 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HMIFHPHL_02163 8.34e-86 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
HMIFHPHL_02164 7.2e-61 - - - S - - - Enterocin A Immunity
HMIFHPHL_02165 2.2e-221 ybcH - - D ko:K06889 - ko00000 Alpha beta
HMIFHPHL_02166 0.0 pepF2 - - E - - - Oligopeptidase F
HMIFHPHL_02167 1.4e-95 - - - K - - - Transcriptional regulator
HMIFHPHL_02168 7.58e-210 - - - - - - - -
HMIFHPHL_02170 2.09e-63 - - - - - - - -
HMIFHPHL_02171 4.98e-47 - - - - - - - -
HMIFHPHL_02172 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HMIFHPHL_02173 1e-89 - - - - - - - -
HMIFHPHL_02174 2.4e-186 - - - S ko:K06889 - ko00000 Dienelactone hydrolase family
HMIFHPHL_02175 9.89e-74 ytpP - - CO - - - Thioredoxin
HMIFHPHL_02176 4.51e-261 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
HMIFHPHL_02177 3.89e-62 - - - - - - - -
HMIFHPHL_02178 1.57e-71 - - - - - - - -
HMIFHPHL_02179 8.1e-105 - - - S - - - Protein of unknown function (DUF2798)
HMIFHPHL_02180 4.05e-98 - - - - - - - -
HMIFHPHL_02181 4.15e-78 - - - - - - - -
HMIFHPHL_02182 4.26e-250 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HMIFHPHL_02183 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
HMIFHPHL_02184 1.63e-95 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HMIFHPHL_02185 3.82e-188 agaD - - G ko:K02747,ko:K02796,ko:K10986 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
HMIFHPHL_02186 2.12e-184 - - - G ko:K02746,ko:K10985 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
HMIFHPHL_02187 6.08e-112 - 2.7.1.191 - K ko:K02745,ko:K02794,ko:K10984 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HMIFHPHL_02188 5.87e-166 - - - K ko:K03710 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HMIFHPHL_02189 1.02e-102 uspA3 - - T - - - universal stress protein
HMIFHPHL_02190 1.19e-201 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HMIFHPHL_02191 3.77e-24 - - - - - - - -
HMIFHPHL_02192 1.09e-55 - - - S - - - zinc-ribbon domain
HMIFHPHL_02193 8.5e-98 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HMIFHPHL_02194 4.05e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
HMIFHPHL_02195 1.38e-30 - - - S - - - Protein of unknown function (DUF2929)
HMIFHPHL_02196 5.31e-285 - - - M - - - Glycosyl transferases group 1
HMIFHPHL_02197 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HMIFHPHL_02198 3.74e-205 - - - S - - - Putative esterase
HMIFHPHL_02199 3.53e-169 - - - K - - - Transcriptional regulator
HMIFHPHL_02200 4.75e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HMIFHPHL_02201 6.08e-179 - - - - - - - -
HMIFHPHL_02202 1.97e-150 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HMIFHPHL_02203 8.05e-179 rrp8 - - K - - - LytTr DNA-binding domain
HMIFHPHL_02204 4e-117 - - - K - - - Domain of unknown function (DUF1836)
HMIFHPHL_02205 6.31e-79 - - - - - - - -
HMIFHPHL_02206 2.61e-96 hsp2 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HMIFHPHL_02207 2.97e-76 - - - - - - - -
HMIFHPHL_02208 0.0 yhdP - - S - - - Transporter associated domain
HMIFHPHL_02209 1.18e-114 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
HMIFHPHL_02210 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
HMIFHPHL_02211 1.17e-270 yttB - - EGP - - - Major Facilitator
HMIFHPHL_02212 2.84e-82 - - - K - - - helix_turn_helix, mercury resistance
HMIFHPHL_02213 1.27e-219 - - - C - - - Zinc-binding dehydrogenase
HMIFHPHL_02214 4.71e-74 - - - S - - - SdpI/YhfL protein family
HMIFHPHL_02215 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HMIFHPHL_02216 0.0 gabR - - K ko:K00375 - ko00000,ko03000 Bacterial regulatory proteins, gntR family
HMIFHPHL_02217 1.02e-277 araT2 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HMIFHPHL_02218 1.84e-204 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMIFHPHL_02219 3.59e-26 - - - - - - - -
HMIFHPHL_02220 2.09e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
HMIFHPHL_02221 5.73e-208 mleR - - K - - - LysR family
HMIFHPHL_02222 1.29e-148 - - - GM - - - NAD(P)H-binding
HMIFHPHL_02223 3.86e-124 - - - K - - - Acetyltransferase (GNAT) family
HMIFHPHL_02224 4.22e-260 - - - EGP - - - Transmembrane secretion effector
HMIFHPHL_02225 7.54e-115 yrxA - - S ko:K07105 - ko00000 3H domain
HMIFHPHL_02226 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMIFHPHL_02227 2.13e-152 - - - K - - - Transcriptional regulator
HMIFHPHL_02228 9.76e-234 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HMIFHPHL_02229 4.29e-173 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HMIFHPHL_02230 1.91e-316 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
HMIFHPHL_02231 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HMIFHPHL_02232 0.0 pbg5 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HMIFHPHL_02233 6.7e-74 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
HMIFHPHL_02234 1.86e-64 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HMIFHPHL_02235 6.37e-169 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
HMIFHPHL_02236 1.4e-181 epsV - - S - - - glycosyl transferase family 2
HMIFHPHL_02237 1.75e-156 pgm7 - - G - - - Phosphoglycerate mutase family
HMIFHPHL_02238 3.11e-106 - - - - - - - -
HMIFHPHL_02239 5.06e-196 - - - S - - - hydrolase
HMIFHPHL_02240 2.5e-234 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMIFHPHL_02241 2.8e-204 - - - EG - - - EamA-like transporter family
HMIFHPHL_02242 4.12e-226 serA1 - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HMIFHPHL_02243 3.78e-132 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HMIFHPHL_02244 0.0 - - - - ko:K21471 - ko00000,ko01000,ko01002,ko01011 -
HMIFHPHL_02245 4.75e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
HMIFHPHL_02246 0.0 - - - M - - - Domain of unknown function (DUF5011)
HMIFHPHL_02247 0.0 - - - M - - - Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HMIFHPHL_02248 4.3e-44 - - - - - - - -
HMIFHPHL_02249 2.55e-166 aroC1 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Type I 3-dehydroquinase
HMIFHPHL_02250 0.0 ycaM - - E - - - amino acid
HMIFHPHL_02251 1.41e-100 - - - K - - - Winged helix DNA-binding domain
HMIFHPHL_02252 4.07e-212 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
HMIFHPHL_02253 2.95e-207 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
HMIFHPHL_02254 1.3e-209 - - - K - - - Transcriptional regulator
HMIFHPHL_02256 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HMIFHPHL_02257 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HMIFHPHL_02258 1.12e-216 oroP - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
HMIFHPHL_02259 6.64e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMIFHPHL_02260 1.09e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HMIFHPHL_02261 1.04e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HMIFHPHL_02262 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HMIFHPHL_02263 3.36e-272 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HMIFHPHL_02264 2.38e-310 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HMIFHPHL_02265 2.46e-220 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HMIFHPHL_02266 7.13e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMIFHPHL_02267 0.0 pucR_2 - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
HMIFHPHL_02268 4.41e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
HMIFHPHL_02269 5.67e-280 pbuG - - S ko:K06901 - ko00000,ko02000 Permease family
HMIFHPHL_02270 4.71e-208 - - - GM - - - NmrA-like family
HMIFHPHL_02271 1.25e-199 - - - T - - - EAL domain
HMIFHPHL_02272 1.85e-121 - - - - - - - -
HMIFHPHL_02273 4.1e-234 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
HMIFHPHL_02274 1.6e-47 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
HMIFHPHL_02275 1.15e-160 - - - E - - - Methionine synthase
HMIFHPHL_02276 6.66e-281 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HMIFHPHL_02277 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HMIFHPHL_02278 5.35e-133 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HMIFHPHL_02279 2.97e-243 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HMIFHPHL_02280 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HMIFHPHL_02281 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMIFHPHL_02282 6.91e-164 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMIFHPHL_02283 1.17e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMIFHPHL_02284 3.39e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HMIFHPHL_02285 2.87e-270 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HMIFHPHL_02286 3.77e-104 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HMIFHPHL_02287 7.9e-305 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
HMIFHPHL_02288 9.92e-143 - - - S - - - NADPH-dependent FMN reductase
HMIFHPHL_02289 4.94e-244 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
HMIFHPHL_02290 4.81e-188 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HMIFHPHL_02291 3.44e-152 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
HMIFHPHL_02292 4.15e-191 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HMIFHPHL_02293 3.7e-233 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
HMIFHPHL_02294 2.05e-178 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_02295 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HMIFHPHL_02296 4.76e-56 - - - - - - - -
HMIFHPHL_02297 8.2e-81 - - - K - - - Transcriptional regulator, GntR family
HMIFHPHL_02298 2.64e-210 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_02299 3.41e-190 - - - - - - - -
HMIFHPHL_02300 2.7e-104 usp5 - - T - - - universal stress protein
HMIFHPHL_02301 1.08e-47 - - - - - - - -
HMIFHPHL_02302 5.7e-95 gtcA - - S - - - Teichoic acid glycosylation protein
HMIFHPHL_02303 1.76e-114 - - - - - - - -
HMIFHPHL_02304 4.01e-65 - - - - - - - -
HMIFHPHL_02305 4.79e-13 - - - - - - - -
HMIFHPHL_02306 5.86e-297 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HMIFHPHL_02307 1.16e-110 - - - F - - - belongs to the nudix hydrolase family
HMIFHPHL_02308 5.07e-150 - - - - - - - -
HMIFHPHL_02309 1.21e-69 - - - - - - - -
HMIFHPHL_02311 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HMIFHPHL_02312 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
HMIFHPHL_02313 4.65e-186 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HMIFHPHL_02314 7.13e-30 - - - S - - - Pentapeptide repeats (8 copies)
HMIFHPHL_02315 1.19e-141 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HMIFHPHL_02316 4.61e-132 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
HMIFHPHL_02317 2.26e-91 - - - FG - - - Scavenger mRNA decapping enzyme C-term binding
HMIFHPHL_02318 6.58e-173 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HMIFHPHL_02319 3.94e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
HMIFHPHL_02320 6.01e-270 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HMIFHPHL_02321 4.43e-294 - - - S - - - Sterol carrier protein domain
HMIFHPHL_02322 1.36e-11 - - - EGP - - - Transmembrane secretion effector
HMIFHPHL_02323 1.97e-110 - - - S - - - Pfam:DUF3816
HMIFHPHL_02324 1.21e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMIFHPHL_02325 3.63e-143 - - - - - - - -
HMIFHPHL_02326 3.09e-229 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HMIFHPHL_02327 3.84e-185 - - - S - - - Peptidase_C39 like family
HMIFHPHL_02328 1.04e-120 - - - S - - - Protein of unknown function (DUF1694)
HMIFHPHL_02330 2.28e-148 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HMIFHPHL_02331 9.38e-189 - - - KT - - - helix_turn_helix, mercury resistance
HMIFHPHL_02332 3.41e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMIFHPHL_02333 1.86e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
HMIFHPHL_02334 1.2e-240 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HMIFHPHL_02335 7.14e-157 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_02336 2.76e-117 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
HMIFHPHL_02337 4.9e-239 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
HMIFHPHL_02338 2.92e-126 ywjB - - H - - - RibD C-terminal domain
HMIFHPHL_02339 1.97e-258 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HMIFHPHL_02340 9.01e-155 - - - S - - - Membrane
HMIFHPHL_02341 2.11e-199 mleP3 - - S ko:K07088 - ko00000 Membrane transport protein
HMIFHPHL_02342 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
HMIFHPHL_02343 2.75e-170 - - - EGP - - - Major Facilitator Superfamily
HMIFHPHL_02344 2.41e-70 - - - EGP - - - Major Facilitator Superfamily
HMIFHPHL_02345 4.18e-162 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HMIFHPHL_02346 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HMIFHPHL_02347 4.03e-104 - - - S - - - Domain of unknown function (DUF4811)
HMIFHPHL_02348 8.99e-133 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HMIFHPHL_02349 4.38e-222 - - - S - - - Conserved hypothetical protein 698
HMIFHPHL_02350 1.14e-191 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
HMIFHPHL_02351 0.0 tagE5 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
HMIFHPHL_02352 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HMIFHPHL_02353 1.09e-56 - - - M - - - LysM domain protein
HMIFHPHL_02354 1.58e-74 - - - M - - - LysM domain
HMIFHPHL_02355 1.66e-118 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Metal binding domain of Ada
HMIFHPHL_02356 6.5e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
HMIFHPHL_02357 2.86e-213 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_02358 5.31e-267 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HMIFHPHL_02359 2.54e-104 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HMIFHPHL_02360 2.77e-46 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HMIFHPHL_02361 3.32e-72 cmd 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
HMIFHPHL_02362 1.94e-99 yphH - - S - - - Cupin domain
HMIFHPHL_02363 1.27e-103 - - - K - - - transcriptional regulator, MerR family
HMIFHPHL_02364 1.7e-298 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HMIFHPHL_02365 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HMIFHPHL_02366 2.88e-155 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_02368 1.19e-150 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HMIFHPHL_02369 3.18e-141 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HMIFHPHL_02370 1.03e-150 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HMIFHPHL_02371 2.08e-110 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HMIFHPHL_02372 8.4e-112 - - - - - - - -
HMIFHPHL_02373 6.25e-112 yvbK - - K - - - GNAT family
HMIFHPHL_02374 9.76e-50 - - - - - - - -
HMIFHPHL_02375 2.81e-64 - - - - - - - -
HMIFHPHL_02376 3.16e-144 pgm8 - - G - - - Histidine phosphatase superfamily (branch 1)
HMIFHPHL_02377 2.65e-78 - - - S - - - Domain of unknown function (DUF4440)
HMIFHPHL_02378 5.25e-201 - - - K - - - LysR substrate binding domain
HMIFHPHL_02379 6.2e-135 - - - GM - - - NAD(P)H-binding
HMIFHPHL_02380 1.37e-246 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HMIFHPHL_02381 1.18e-193 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HMIFHPHL_02382 1.28e-45 - - - - - - - -
HMIFHPHL_02383 2.1e-99 - - - T - - - Belongs to the universal stress protein A family
HMIFHPHL_02384 2.09e-124 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
HMIFHPHL_02385 5.89e-161 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HMIFHPHL_02386 3.28e-79 - - - - - - - -
HMIFHPHL_02387 9.15e-132 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HMIFHPHL_02388 3.31e-283 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HMIFHPHL_02389 1.86e-132 - - - M - - - Protein of unknown function (DUF3737)
HMIFHPHL_02390 5.17e-249 - - - C - - - Aldo/keto reductase family
HMIFHPHL_02392 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HMIFHPHL_02393 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HMIFHPHL_02394 3.85e-315 - - - EGP - - - Major Facilitator
HMIFHPHL_02398 1.32e-304 yhgE - - V ko:K01421 - ko00000 domain protein
HMIFHPHL_02399 3.01e-124 - - - K - - - Transcriptional regulator (TetR family)
HMIFHPHL_02400 6.88e-71 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HMIFHPHL_02401 8.76e-195 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
HMIFHPHL_02402 1.39e-134 yokL3 - - J - - - Acetyltransferase (GNAT) domain
HMIFHPHL_02403 3.05e-126 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HMIFHPHL_02404 6.3e-169 - - - M - - - Phosphotransferase enzyme family
HMIFHPHL_02405 2.34e-284 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HMIFHPHL_02406 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
HMIFHPHL_02407 1.57e-188 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HMIFHPHL_02408 0.0 - - - S - - - Predicted membrane protein (DUF2207)
HMIFHPHL_02409 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
HMIFHPHL_02410 1.15e-265 - - - EGP - - - Major facilitator Superfamily
HMIFHPHL_02411 1.13e-221 ropB - - K - - - Helix-turn-helix XRE-family like proteins
HMIFHPHL_02412 1.18e-225 - 3.4.11.5 - I ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HMIFHPHL_02413 0.0 - - - E ko:K03294 - ko00000 Amino acid permease
HMIFHPHL_02414 2.83e-297 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
HMIFHPHL_02415 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
HMIFHPHL_02416 2.85e-206 - - - I - - - alpha/beta hydrolase fold
HMIFHPHL_02417 1.01e-167 treR - - K ko:K03486 - ko00000,ko03000 UTRA
HMIFHPHL_02418 0.0 - - - - - - - -
HMIFHPHL_02419 2e-52 - - - S - - - Cytochrome B5
HMIFHPHL_02420 8.68e-118 pts21A - - G ko:K02755 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HMIFHPHL_02421 2.05e-279 - - - T - - - Diguanylate cyclase, GGDEF domain
HMIFHPHL_02422 1.63e-162 - - - T - - - Putative diguanylate phosphodiesterase
HMIFHPHL_02423 3.83e-135 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMIFHPHL_02424 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
HMIFHPHL_02425 1.56e-108 - - - - - - - -
HMIFHPHL_02426 5.97e-96 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HMIFHPHL_02427 1.59e-243 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMIFHPHL_02428 7.3e-245 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMIFHPHL_02429 3.7e-30 - - - - - - - -
HMIFHPHL_02430 7.03e-74 - - - - - - - -
HMIFHPHL_02431 2.33e-43 - - - - - - - -
HMIFHPHL_02432 3.46e-210 - - - K - - - LysR substrate binding domain
HMIFHPHL_02433 2.4e-311 - - - P - - - Sodium:sulfate symporter transmembrane region
HMIFHPHL_02434 0.0 - 4.1.1.98 - H ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HMIFHPHL_02435 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HMIFHPHL_02436 2.29e-183 - - - S - - - zinc-ribbon domain
HMIFHPHL_02438 3.54e-49 - - - - - - - -
HMIFHPHL_02439 1.48e-171 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
HMIFHPHL_02440 2.35e-231 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HMIFHPHL_02441 0.0 - - - I - - - acetylesterase activity
HMIFHPHL_02442 8.38e-174 - - - M - - - Collagen binding domain
HMIFHPHL_02443 1.48e-107 - - - M - - - Collagen binding domain
HMIFHPHL_02444 3.43e-206 yicL - - EG - - - EamA-like transporter family
HMIFHPHL_02445 1.38e-162 - - - E - - - lipolytic protein G-D-S-L family
HMIFHPHL_02446 2.13e-140 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
HMIFHPHL_02447 7.36e-68 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
HMIFHPHL_02448 4.17e-144 - - - K - - - Transcriptional regulator C-terminal region
HMIFHPHL_02449 8.76e-63 - - - K - - - HxlR-like helix-turn-helix
HMIFHPHL_02450 6.42e-65 - - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
HMIFHPHL_02455 1.86e-71 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HMIFHPHL_02456 3.61e-78 agrC 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HMIFHPHL_02457 4.35e-206 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HMIFHPHL_02458 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HMIFHPHL_02459 5.24e-124 - - - K - - - Transcriptional regulator, MarR family
HMIFHPHL_02460 8.08e-154 ydgI3 - - C - - - Nitroreductase family
HMIFHPHL_02461 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HMIFHPHL_02462 2.28e-173 - - - S ko:K05833 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HMIFHPHL_02463 6.09e-124 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HMIFHPHL_02464 7.28e-218 XK27_00670 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HMIFHPHL_02465 0.0 - - - - - - - -
HMIFHPHL_02466 1.4e-82 - - - - - - - -
HMIFHPHL_02467 2.62e-240 - - - S - - - Cell surface protein
HMIFHPHL_02468 1.27e-137 - - - S - - - WxL domain surface cell wall-binding
HMIFHPHL_02469 1.91e-124 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
HMIFHPHL_02470 2.78e-158 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
HMIFHPHL_02471 1.28e-180 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
HMIFHPHL_02472 1.88e-192 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
HMIFHPHL_02473 3.96e-196 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
HMIFHPHL_02474 1.04e-269 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
HMIFHPHL_02476 1.15e-43 - - - - - - - -
HMIFHPHL_02477 2.93e-169 zmp3 - - O - - - Zinc-dependent metalloprotease
HMIFHPHL_02478 2.88e-106 gtcA3 - - S - - - GtrA-like protein
HMIFHPHL_02479 1.36e-156 - - - K - - - Helix-turn-helix XRE-family like proteins
HMIFHPHL_02480 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HMIFHPHL_02481 1.18e-94 usp2 - - T - - - Belongs to the universal stress protein A family
HMIFHPHL_02482 7.03e-62 - - - - - - - -
HMIFHPHL_02483 1.81e-150 - - - S - - - SNARE associated Golgi protein
HMIFHPHL_02484 3.36e-62 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
HMIFHPHL_02485 7.89e-124 - - - P - - - Cadmium resistance transporter
HMIFHPHL_02486 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_02487 0.0 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
HMIFHPHL_02488 5.83e-84 - - - - - - - -
HMIFHPHL_02489 1.58e-204 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HMIFHPHL_02490 1.21e-73 - - - - - - - -
HMIFHPHL_02491 3.41e-192 - - - K - - - Helix-turn-helix domain
HMIFHPHL_02492 3.21e-99 pts23A - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HMIFHPHL_02493 7.47e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HMIFHPHL_02494 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMIFHPHL_02495 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HMIFHPHL_02496 5.04e-234 - - - GM - - - Male sterility protein
HMIFHPHL_02497 2.1e-99 - - - K - - - helix_turn_helix, mercury resistance
HMIFHPHL_02498 6.58e-94 - - - M - - - LysM domain
HMIFHPHL_02499 1.23e-129 - - - M - - - Lysin motif
HMIFHPHL_02500 3.95e-50 - - - S - - - SdpI/YhfL protein family
HMIFHPHL_02501 1.58e-72 nudA - - S - - - ASCH
HMIFHPHL_02502 2.35e-211 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HMIFHPHL_02503 8.76e-121 - - - - - - - -
HMIFHPHL_02504 3.18e-154 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
HMIFHPHL_02505 8.51e-268 - - - T - - - diguanylate cyclase
HMIFHPHL_02506 7.43e-97 - - - S - - - Psort location Cytoplasmic, score
HMIFHPHL_02507 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
HMIFHPHL_02508 2.69e-276 - - - - - - - -
HMIFHPHL_02509 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HMIFHPHL_02510 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_02511 2.65e-289 amd - - E - - - Peptidase family M20/M25/M40
HMIFHPHL_02512 5.97e-209 yhxD - - IQ - - - KR domain
HMIFHPHL_02514 1.14e-91 - - - - - - - -
HMIFHPHL_02515 2.03e-184 - - - K - - - Helix-turn-helix XRE-family like proteins
HMIFHPHL_02516 0.0 - - - E - - - Amino Acid
HMIFHPHL_02517 1.67e-86 lysM - - M - - - LysM domain
HMIFHPHL_02518 4.2e-286 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
HMIFHPHL_02519 6.8e-272 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
HMIFHPHL_02520 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HMIFHPHL_02521 3.65e-59 - - - S - - - Cupredoxin-like domain
HMIFHPHL_02522 7.85e-84 - - - S - - - Cupredoxin-like domain
HMIFHPHL_02523 0.0 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HMIFHPHL_02524 2.81e-181 - - - K - - - Helix-turn-helix domain
HMIFHPHL_02525 7.02e-50 - - - S ko:K07343 - ko00000 TfoX C-terminal domain
HMIFHPHL_02526 1.77e-288 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HMIFHPHL_02527 5.31e-104 - - - - - - - -
HMIFHPHL_02528 1.18e-183 - - - - - - - -
HMIFHPHL_02529 2.69e-99 - - - - - - - -
HMIFHPHL_02530 5.14e-246 - - - S - - - Cell surface protein
HMIFHPHL_02531 9.97e-136 - - - S - - - WxL domain surface cell wall-binding
HMIFHPHL_02532 6.57e-226 - - - C - - - Alcohol dehydrogenase GroES-like domain
HMIFHPHL_02533 5.83e-87 - - - S - - - Iron-sulphur cluster biosynthesis
HMIFHPHL_02534 2.07e-147 - - - S - - - GyrI-like small molecule binding domain
HMIFHPHL_02535 1.25e-240 ynjC - - S - - - Cell surface protein
HMIFHPHL_02537 2.7e-131 - - - S - - - WxL domain surface cell wall-binding
HMIFHPHL_02538 1.47e-83 - - - - - - - -
HMIFHPHL_02539 4.86e-307 - - - NU - - - Mycoplasma protein of unknown function, DUF285
HMIFHPHL_02540 4.8e-156 - - - - - - - -
HMIFHPHL_02541 1.02e-147 - - - S - - - Haloacid dehalogenase-like hydrolase
HMIFHPHL_02542 3.25e-81 ytcD - - K - - - Transcriptional regulator, HxlR family
HMIFHPHL_02543 1.81e-272 - - - EGP - - - Major Facilitator
HMIFHPHL_02544 7.81e-148 - - - M - - - ErfK YbiS YcfS YnhG
HMIFHPHL_02545 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HMIFHPHL_02546 1.38e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HMIFHPHL_02547 1.77e-282 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HMIFHPHL_02548 1.59e-130 - - - K - - - Bacterial regulatory proteins, tetR family
HMIFHPHL_02549 5.35e-216 - - - GM - - - NmrA-like family
HMIFHPHL_02550 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HMIFHPHL_02551 0.0 - - - M - - - Glycosyl hydrolases family 25
HMIFHPHL_02552 1.62e-62 - - - S - - - Domain of unknown function (DUF1905)
HMIFHPHL_02553 1.27e-83 - - - K - - - HxlR-like helix-turn-helix
HMIFHPHL_02554 3.27e-170 - - - S - - - KR domain
HMIFHPHL_02555 2.64e-122 - - - K - - - Bacterial regulatory proteins, tetR family
HMIFHPHL_02556 3.47e-244 - 1.1.1.219 - GM ko:K00091 - ko00000,ko01000 Male sterility protein
HMIFHPHL_02557 1.27e-129 - - - S - - - Protein of unknown function (DUF1211)
HMIFHPHL_02558 6.6e-228 ydhF - - S - - - Aldo keto reductase
HMIFHPHL_02559 0.0 yfjF - - U - - - Sugar (and other) transporter
HMIFHPHL_02560 7.57e-141 - - - K - - - Bacterial regulatory proteins, tetR family
HMIFHPHL_02561 3.35e-217 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HMIFHPHL_02562 6.37e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HMIFHPHL_02563 1.81e-228 fhuB - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMIFHPHL_02564 1.92e-218 fhuG - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMIFHPHL_02565 3.74e-120 - - - K - - - Bacterial regulatory proteins, tetR family
HMIFHPHL_02566 3.2e-209 - - - GM - - - NmrA-like family
HMIFHPHL_02567 2.47e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HMIFHPHL_02568 9.43e-95 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HMIFHPHL_02569 7.45e-194 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HMIFHPHL_02570 3.18e-84 - - - K - - - helix_turn_helix, mercury resistance
HMIFHPHL_02571 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
HMIFHPHL_02572 2.76e-229 - - - S - - - Bacterial protein of unknown function (DUF916)
HMIFHPHL_02573 6.38e-115 - - - S - - - WxL domain surface cell wall-binding
HMIFHPHL_02574 8e-266 - - - NU - - - Mycoplasma protein of unknown function, DUF285
HMIFHPHL_02575 1.97e-151 - - - K - - - Bacterial regulatory proteins, tetR family
HMIFHPHL_02576 0.0 lepA2 - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMIFHPHL_02577 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
HMIFHPHL_02578 4.54e-202 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
HMIFHPHL_02580 0.0 - - - S - - - MucBP domain
HMIFHPHL_02582 9.82e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HMIFHPHL_02583 1.9e-148 - - - K ko:K03489 - ko00000,ko03000 UTRA
HMIFHPHL_02584 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HMIFHPHL_02585 9.2e-317 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMIFHPHL_02586 2.09e-85 - - - - - - - -
HMIFHPHL_02587 5.15e-16 - - - - - - - -
HMIFHPHL_02588 5.61e-54 pcaC 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
HMIFHPHL_02589 3.41e-31 - - - K - - - helix_turn_helix, mercury resistance
HMIFHPHL_02590 5.75e-83 - - - S - - - Protein of unknown function (DUF1093)
HMIFHPHL_02591 4.17e-280 - - - S - - - Membrane
HMIFHPHL_02592 8.21e-57 - - - S - - - Protein of unknown function (DUF3781)
HMIFHPHL_02593 4.12e-123 yoaZ - - S - - - intracellular protease amidase
HMIFHPHL_02594 5.57e-69 - - - K - - - HxlR-like helix-turn-helix
HMIFHPHL_02595 3.91e-189 - - - C - - - Alcohol dehydrogenase GroES-like domain
HMIFHPHL_02596 5.49e-261 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
HMIFHPHL_02597 3.12e-118 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
HMIFHPHL_02598 1.9e-153 yciB - - M - - - ErfK YbiS YcfS YnhG
HMIFHPHL_02599 6.79e-53 - - - - - - - -
HMIFHPHL_02600 5.06e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMIFHPHL_02601 5.35e-232 ydbI - - K - - - AI-2E family transporter
HMIFHPHL_02602 2.66e-270 xylR - - GK - - - ROK family
HMIFHPHL_02603 5.21e-151 - - - - - - - -
HMIFHPHL_02604 3.66e-295 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HMIFHPHL_02605 1.16e-210 - - - - - - - -
HMIFHPHL_02606 3.49e-184 pkn2 - - KLT - - - Protein tyrosine kinase
HMIFHPHL_02607 2.46e-35 pkn2 - - KLT - - - Protein tyrosine kinase
HMIFHPHL_02608 9.58e-35 - - - S - - - Protein of unknown function (DUF4064)
HMIFHPHL_02609 2.47e-125 - - - S - - - Domain of unknown function (DUF4352)
HMIFHPHL_02610 7.97e-98 - - - S - - - Psort location Cytoplasmic, score
HMIFHPHL_02612 5.01e-71 - - - - - - - -
HMIFHPHL_02613 1.37e-140 - - - S ko:K07090 - ko00000 membrane transporter protein
HMIFHPHL_02614 5.93e-73 - - - S - - - branched-chain amino acid
HMIFHPHL_02615 2.05e-167 - - - E - - - branched-chain amino acid
HMIFHPHL_02616 6.77e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HMIFHPHL_02617 6.25e-304 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HMIFHPHL_02618 5.61e-273 hpk31 - - T - - - Histidine kinase
HMIFHPHL_02619 1.14e-159 vanR - - K - - - response regulator
HMIFHPHL_02620 2.4e-161 - - - S - - - Protein of unknown function (DUF1275)
HMIFHPHL_02621 3.3e-208 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HMIFHPHL_02622 3.49e-270 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMIFHPHL_02623 3.49e-160 - - - S - - - Protein of unknown function (DUF1129)
HMIFHPHL_02624 6.6e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMIFHPHL_02625 1.4e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
HMIFHPHL_02626 6.14e-202 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HMIFHPHL_02627 1.01e-175 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
HMIFHPHL_02628 7.39e-192 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HMIFHPHL_02629 3e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HMIFHPHL_02630 1.66e-288 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
HMIFHPHL_02631 6.93e-198 - - - S - - - Bacterial membrane protein, YfhO
HMIFHPHL_02632 2.58e-189 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HMIFHPHL_02633 3.36e-216 - - - K - - - LysR substrate binding domain
HMIFHPHL_02634 8.42e-302 - - - EK - - - Aminotransferase, class I
HMIFHPHL_02635 1.11e-169 fliY - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HMIFHPHL_02636 2.11e-158 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HMIFHPHL_02637 3.02e-176 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_02638 1.03e-160 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HMIFHPHL_02639 8.83e-127 - - - KT - - - response to antibiotic
HMIFHPHL_02640 8.52e-70 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
HMIFHPHL_02641 6.03e-133 - - - S - - - Protein of unknown function (DUF1700)
HMIFHPHL_02642 1.95e-201 - - - S - - - Putative adhesin
HMIFHPHL_02643 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HMIFHPHL_02644 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HMIFHPHL_02645 1.5e-232 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
HMIFHPHL_02646 3.73e-263 - - - S - - - DUF218 domain
HMIFHPHL_02647 9.95e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
HMIFHPHL_02648 2.93e-151 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HMIFHPHL_02649 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMIFHPHL_02650 6.26e-101 - - - - - - - -
HMIFHPHL_02651 1.7e-262 - 4.1.1.45 - E ko:K03392,ko:K07045 ko00380,ko01100,map00380,map01100 ko00000,ko00001,ko00002,ko01000 amidohydrolase
HMIFHPHL_02652 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HMIFHPHL_02653 2.01e-307 - - - S - - - Neutral/alkaline non-lysosomal ceramidase, N-terminal
HMIFHPHL_02654 7.42e-296 - - - - - - - -
HMIFHPHL_02655 3.91e-211 - - - K - - - LysR substrate binding domain
HMIFHPHL_02656 2.21e-193 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
HMIFHPHL_02657 8.33e-189 - - - S - - - haloacid dehalogenase-like hydrolase
HMIFHPHL_02658 2.24e-116 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HMIFHPHL_02659 0.0 mngB 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Glycosyl hydrolases family 38 N-terminal domain
HMIFHPHL_02660 6.69e-155 fptC - - U ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase system, EIIC
HMIFHPHL_02661 2.52e-35 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HMIFHPHL_02662 5.55e-22 - - - G ko:K11203 - ko00000,ko00002,ko02000 PTS system, fructose subfamily
HMIFHPHL_02663 2.11e-104 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMIFHPHL_02664 4.08e-101 - - - K - - - MerR family regulatory protein
HMIFHPHL_02665 1.52e-199 - - - GM - - - NmrA-like family
HMIFHPHL_02666 0.0 pts28ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HMIFHPHL_02667 2.94e-163 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
HMIFHPHL_02669 5.01e-129 - - - S - - - NADPH-dependent FMN reductase
HMIFHPHL_02670 3.43e-303 - - - S - - - module of peptide synthetase
HMIFHPHL_02671 2.08e-138 - - - - - - - -
HMIFHPHL_02672 1.55e-114 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HMIFHPHL_02673 7.43e-77 - - - S - - - Enterocin A Immunity
HMIFHPHL_02674 3.74e-48 - - - S - - - Phospholipase_D-nuclease N-terminal
HMIFHPHL_02675 1.54e-214 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
HMIFHPHL_02676 2.8e-135 - - - J - - - Acetyltransferase (GNAT) domain
HMIFHPHL_02677 4.14e-84 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
HMIFHPHL_02678 2.88e-164 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
HMIFHPHL_02679 3.84e-186 WQ51_01275 - - S - - - EDD domain protein, DegV family
HMIFHPHL_02680 1.03e-34 - - - - - - - -
HMIFHPHL_02681 1.48e-152 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
HMIFHPHL_02682 1.83e-211 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
HMIFHPHL_02683 1.6e-140 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
HMIFHPHL_02684 8.52e-212 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
HMIFHPHL_02685 4.68e-235 - - - D ko:K06889 - ko00000 Alpha beta
HMIFHPHL_02686 1.67e-250 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HMIFHPHL_02687 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HMIFHPHL_02688 2.49e-73 - - - S - - - Enterocin A Immunity
HMIFHPHL_02689 7.41e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HMIFHPHL_02690 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMIFHPHL_02691 7.21e-236 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMIFHPHL_02692 2.5e-188 ptp2 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HMIFHPHL_02693 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMIFHPHL_02695 7.21e-81 - - - - - - - -
HMIFHPHL_02696 0.0 yhdG - - E ko:K03294 - ko00000 C-terminus of AA_permease
HMIFHPHL_02698 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HMIFHPHL_02699 4.34e-211 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMIFHPHL_02700 1.54e-228 ydbI - - K - - - AI-2E family transporter
HMIFHPHL_02701 3.95e-275 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HMIFHPHL_02702 1.15e-77 - - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
HMIFHPHL_02703 1.97e-60 qacH - - U ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
HMIFHPHL_02704 2.94e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
HMIFHPHL_02705 7.27e-73 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
HMIFHPHL_02706 1.3e-207 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
HMIFHPHL_02707 8.03e-28 - - - - - - - -
HMIFHPHL_02708 3.91e-124 tag2 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HMIFHPHL_02709 1.37e-271 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
HMIFHPHL_02710 3.47e-135 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
HMIFHPHL_02711 2.75e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HMIFHPHL_02712 1.8e-134 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
HMIFHPHL_02713 1.59e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HMIFHPHL_02714 9.61e-84 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HMIFHPHL_02715 4.08e-107 cvpA - - S - - - Colicin V production protein
HMIFHPHL_02716 5.61e-216 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HMIFHPHL_02717 5.3e-316 - - - EGP - - - Major Facilitator
HMIFHPHL_02719 1.07e-52 - - - - - - - -
HMIFHPHL_02720 3.74e-125 - - - V - - - VanZ like family
HMIFHPHL_02721 1.87e-249 - - - V - - - Beta-lactamase
HMIFHPHL_02722 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
HMIFHPHL_02723 1.12e-206 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMIFHPHL_02724 8.93e-71 - - - S - - - Pfam:DUF59
HMIFHPHL_02725 7.39e-224 ydhF - - S - - - Aldo keto reductase
HMIFHPHL_02726 2.42e-127 - - - FG - - - HIT domain
HMIFHPHL_02727 5.09e-51 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
HMIFHPHL_02728 4.29e-101 - - - - - - - -
HMIFHPHL_02729 5.3e-157 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HMIFHPHL_02730 0.0 - - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
HMIFHPHL_02731 0.0 cadA - - P - - - P-type ATPase
HMIFHPHL_02733 1.57e-158 - - - S - - - YjbR
HMIFHPHL_02734 4.34e-281 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
HMIFHPHL_02735 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HMIFHPHL_02736 5.84e-255 glmS2 - - M - - - SIS domain
HMIFHPHL_02737 3.58e-36 - - - S - - - Belongs to the LOG family
HMIFHPHL_02738 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HMIFHPHL_02739 7.23e-316 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HMIFHPHL_02740 2.48e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HMIFHPHL_02741 6.74e-112 pgpA - - I - - - Phosphatidylglycerophosphatase A
HMIFHPHL_02742 1.36e-209 - - - GM - - - NmrA-like family
HMIFHPHL_02743 4.31e-86 - - - K ko:K22296 - ko00000,ko03000 Winged helix DNA-binding domain
HMIFHPHL_02744 9.97e-94 spxA - - P ko:K16509 - ko00000 ArsC family
HMIFHPHL_02745 2e-86 yeaO - - S - - - Protein of unknown function, DUF488
HMIFHPHL_02746 1.7e-70 - - - - - - - -
HMIFHPHL_02747 4.98e-275 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
HMIFHPHL_02748 2.11e-82 - - - - - - - -
HMIFHPHL_02749 1.11e-111 - - - - - - - -
HMIFHPHL_02750 4.58e-103 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HMIFHPHL_02751 2.27e-74 - - - - - - - -
HMIFHPHL_02752 4.79e-21 - - - - - - - -
HMIFHPHL_02753 1.2e-148 - - - GM - - - NmrA-like family
HMIFHPHL_02754 7.23e-107 - - - S ko:K02348 - ko00000 GNAT family
HMIFHPHL_02755 1.63e-203 - - - EG - - - EamA-like transporter family
HMIFHPHL_02756 2.66e-155 - - - S - - - membrane
HMIFHPHL_02757 2.55e-145 - - - S - - - VIT family
HMIFHPHL_02758 8.48e-241 pva2 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
HMIFHPHL_02759 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HMIFHPHL_02760 8.01e-97 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
HMIFHPHL_02761 4.26e-54 - - - - - - - -
HMIFHPHL_02762 8.43e-97 - - - S - - - COG NOG18757 non supervised orthologous group
HMIFHPHL_02763 1.45e-313 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
HMIFHPHL_02764 7.21e-35 - - - - - - - -
HMIFHPHL_02765 6.02e-64 - - - - - - - -
HMIFHPHL_02766 8.4e-85 - - - S - - - Protein of unknown function (DUF1398)
HMIFHPHL_02767 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HMIFHPHL_02768 1.77e-282 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HMIFHPHL_02769 6.99e-230 ybcH - - D ko:K06889 - ko00000 Alpha beta
HMIFHPHL_02770 6.1e-101 - - - K - - - Domain of unknown function (DUF1836)
HMIFHPHL_02771 1.14e-110 - - - F - - - Nucleoside 2-deoxyribosyltransferase
HMIFHPHL_02772 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
HMIFHPHL_02773 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HMIFHPHL_02774 2.8e-205 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
HMIFHPHL_02775 4.55e-208 yvgN - - C - - - Aldo keto reductase
HMIFHPHL_02776 2.57e-171 - - - S - - - Putative threonine/serine exporter
HMIFHPHL_02777 2.07e-102 - - - S - - - Threonine/Serine exporter, ThrE
HMIFHPHL_02779 2.33e-209 comA - - V ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HMIFHPHL_02782 3.68e-57 - - - S - - - Protein of unknown function (DUF1093)
HMIFHPHL_02783 5.43e-190 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HMIFHPHL_02784 4.88e-117 ymdB - - S - - - Macro domain protein
HMIFHPHL_02785 6.47e-124 - - - K ko:K22041 - ko00000,ko03000 transcriptional regulator
HMIFHPHL_02786 1.58e-66 - - - - - - - -
HMIFHPHL_02787 9.81e-212 - - - S - - - Protein of unknown function (DUF1002)
HMIFHPHL_02788 0.0 - - - - - - - -
HMIFHPHL_02789 1.94e-245 - - - S - - - Bacterial protein of unknown function (DUF916)
HMIFHPHL_02790 5.48e-171 - - - S - - - WxL domain surface cell wall-binding
HMIFHPHL_02791 1.63e-176 yesN - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HMIFHPHL_02792 5.33e-114 - - - K - - - Winged helix DNA-binding domain
HMIFHPHL_02793 3.81e-150 - - - K - - - Bacterial regulatory proteins, tetR family
HMIFHPHL_02794 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
HMIFHPHL_02795 4.45e-38 - - - - - - - -
HMIFHPHL_02796 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
HMIFHPHL_02797 8.22e-107 - - - M - - - PFAM NLP P60 protein
HMIFHPHL_02798 6.18e-71 - - - - - - - -
HMIFHPHL_02799 9.96e-82 - - - - - - - -
HMIFHPHL_02802 9.32e-84 - - - V - - - VanZ like family
HMIFHPHL_02803 4.18e-16 - - - K - - - Cro/C1-type HTH DNA-binding domain
HMIFHPHL_02804 1.53e-139 - - - - - - - -
HMIFHPHL_02805 1.22e-68 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
HMIFHPHL_02806 1.32e-203 - - - S ko:K07045 - ko00000 Amidohydrolase
HMIFHPHL_02807 2.55e-131 - - - K - - - transcriptional regulator
HMIFHPHL_02808 5.05e-232 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
HMIFHPHL_02809 4.16e-175 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HMIFHPHL_02810 7.15e-164 - - - S - - - Gram-negative-bacterium-type cell wall biogenesis
HMIFHPHL_02811 1.9e-230 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HMIFHPHL_02812 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
HMIFHPHL_02813 9.44e-183 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HMIFHPHL_02814 2.34e-72 trxA3 - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin-like domain
HMIFHPHL_02815 2.79e-54 yrkD - - S - - - Metal-sensitive transcriptional repressor
HMIFHPHL_02816 1.01e-26 - - - - - - - -
HMIFHPHL_02817 5.82e-124 dpsB - - P - - - Belongs to the Dps family
HMIFHPHL_02818 2.98e-44 copZ - - P - - - Heavy-metal-associated domain
HMIFHPHL_02819 2.59e-152 rcfA - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
HMIFHPHL_02820 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HMIFHPHL_02821 5.23e-107 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HMIFHPHL_02822 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
HMIFHPHL_02823 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
HMIFHPHL_02824 1.22e-221 - - - S - - - Cell surface protein
HMIFHPHL_02825 1.01e-158 - - - S - - - WxL domain surface cell wall-binding
HMIFHPHL_02826 4.23e-129 - - - S - - - WxL domain surface cell wall-binding
HMIFHPHL_02827 7.83e-60 - - - - - - - -
HMIFHPHL_02828 1.72e-135 yezE - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
HMIFHPHL_02829 1.03e-65 - - - - - - - -
HMIFHPHL_02830 1.19e-313 - - - S - - - Putative metallopeptidase domain
HMIFHPHL_02831 4.03e-283 - - - S - - - associated with various cellular activities
HMIFHPHL_02832 3.94e-140 aqpZ - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HMIFHPHL_02833 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
HMIFHPHL_02834 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HMIFHPHL_02835 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HMIFHPHL_02836 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
HMIFHPHL_02837 2.74e-241 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HMIFHPHL_02838 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HMIFHPHL_02839 1.23e-294 - - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
HMIFHPHL_02840 0.0 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HMIFHPHL_02841 5.06e-298 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
HMIFHPHL_02842 1.29e-235 - - - K - - - helix_turn_helix, arabinose operon control protein
HMIFHPHL_02843 3.9e-143 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
HMIFHPHL_02844 3.4e-100 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HMIFHPHL_02845 1.19e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HMIFHPHL_02846 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HMIFHPHL_02847 2.09e-244 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HMIFHPHL_02848 1.65e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HMIFHPHL_02849 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HMIFHPHL_02850 2.24e-236 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
HMIFHPHL_02851 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HMIFHPHL_02852 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HMIFHPHL_02853 1.43e-251 galM3 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HMIFHPHL_02854 3.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HMIFHPHL_02855 5.16e-248 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
HMIFHPHL_02856 2.36e-84 - - - S - - - pyridoxamine 5-phosphate
HMIFHPHL_02857 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HMIFHPHL_02858 3.68e-230 apbE3 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMIFHPHL_02859 1.17e-168 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HMIFHPHL_02860 4.63e-275 - - - G - - - Transporter
HMIFHPHL_02861 1.66e-215 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMIFHPHL_02862 5.79e-209 - - - K - - - Transcriptional regulator, LysR family
HMIFHPHL_02863 4.07e-269 - - - G - - - Major Facilitator Superfamily
HMIFHPHL_02864 2.09e-83 - - - - - - - -
HMIFHPHL_02865 2.63e-200 estA - - S - - - Putative esterase
HMIFHPHL_02866 1.82e-172 - - - K - - - UTRA domain
HMIFHPHL_02867 1.87e-316 pts29C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMIFHPHL_02868 8.04e-208 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HMIFHPHL_02869 8.36e-203 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
HMIFHPHL_02870 2.26e-269 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HMIFHPHL_02871 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HMIFHPHL_02872 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HMIFHPHL_02873 3.72e-200 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HMIFHPHL_02874 0.0 pbg9 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HMIFHPHL_02875 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HMIFHPHL_02876 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HMIFHPHL_02877 1.3e-203 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HMIFHPHL_02878 0.0 treP 2.4.1.64 GH65 G ko:K05342 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HMIFHPHL_02879 1.08e-221 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
HMIFHPHL_02880 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HMIFHPHL_02881 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
HMIFHPHL_02883 2.83e-237 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HMIFHPHL_02884 2.58e-186 yxeH - - S - - - hydrolase
HMIFHPHL_02885 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HMIFHPHL_02886 8.34e-147 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HMIFHPHL_02887 2.47e-307 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HMIFHPHL_02888 4.22e-60 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system galactitol-specific IIB component
HMIFHPHL_02889 6.42e-101 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMIFHPHL_02890 0.0 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMIFHPHL_02891 4.53e-146 gph3 - - S - - - Haloacid dehalogenase-like hydrolase
HMIFHPHL_02892 5.26e-247 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
HMIFHPHL_02893 8.37e-296 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HMIFHPHL_02894 6e-60 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HMIFHPHL_02895 4.66e-105 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMIFHPHL_02896 3.05e-161 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
HMIFHPHL_02897 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HMIFHPHL_02898 3.5e-93 - - - S - - - Protein of unknown function (DUF1694)
HMIFHPHL_02899 3.25e-131 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
HMIFHPHL_02900 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
HMIFHPHL_02901 1.06e-175 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HMIFHPHL_02902 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
HMIFHPHL_02903 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HMIFHPHL_02904 3.44e-262 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
HMIFHPHL_02905 1.06e-159 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HMIFHPHL_02906 5.6e-292 - - - S - - - Pyridine nucleotide-disulphide oxidoreductase
HMIFHPHL_02907 2.43e-91 - - - S - - - Pyrimidine dimer DNA glycosylase
HMIFHPHL_02908 2.1e-116 - - - T - - - ECF transporter, substrate-specific component
HMIFHPHL_02909 1.06e-16 - - - - - - - -
HMIFHPHL_02910 1.96e-21 ytgB - - S - - - Transglycosylase associated protein
HMIFHPHL_02911 0.0 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
HMIFHPHL_02912 1.32e-101 nrp - - K ko:K16509 - ko00000 ArsC family
HMIFHPHL_02913 3.67e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HMIFHPHL_02914 7.01e-286 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HMIFHPHL_02915 3.82e-24 - - - - - - - -
HMIFHPHL_02916 1.01e-125 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HMIFHPHL_02917 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
HMIFHPHL_02919 8.03e-256 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HMIFHPHL_02920 0.0 pox4 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HMIFHPHL_02921 5.03e-95 - - - K - - - Transcriptional regulator
HMIFHPHL_02922 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HMIFHPHL_02923 1.65e-93 yueI - - S - - - Protein of unknown function (DUF1694)
HMIFHPHL_02924 1.45e-162 - - - S - - - Membrane
HMIFHPHL_02925 7.58e-210 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HMIFHPHL_02926 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
HMIFHPHL_02927 4.22e-74 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
HMIFHPHL_02928 0.0 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HMIFHPHL_02929 2.67e-310 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
HMIFHPHL_02930 1.44e-230 rhaR - - K - - - helix_turn_helix, arabinose operon control protein
HMIFHPHL_02931 1.49e-179 - - - K - - - DeoR C terminal sensor domain
HMIFHPHL_02932 3.71e-105 pts36A 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMIFHPHL_02933 2.47e-68 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HMIFHPHL_02934 0.0 pts36C - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HMIFHPHL_02936 7.16e-173 - 4.1.2.17 - G ko:K01628 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Class II Aldolase and Adducin N-terminal domain
HMIFHPHL_02937 1.17e-55 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HMIFHPHL_02939 4.18e-27 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HMIFHPHL_02941 1.93e-43 glvR - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
HMIFHPHL_02942 2.97e-288 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HMIFHPHL_02943 5.05e-299 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
HMIFHPHL_02944 2.22e-88 - - - S - - - Haloacid dehalogenase-like hydrolase
HMIFHPHL_02946 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HMIFHPHL_02947 9e-310 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
HMIFHPHL_02948 2.6e-234 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
HMIFHPHL_02949 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HMIFHPHL_02950 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HMIFHPHL_02951 8.82e-122 - - - U - - - Protein of unknown function DUF262
HMIFHPHL_02952 6.12e-82 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
HMIFHPHL_02953 9.65e-307 dinF - - V - - - MatE
HMIFHPHL_02955 1.04e-219 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HMIFHPHL_02957 1.23e-11 - - - L ko:K07487 - ko00000 Transposase
HMIFHPHL_02958 0.0 bgl 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HMIFHPHL_02959 1.76e-199 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HMIFHPHL_02960 0.0 - 2.3.1.204, 3.2.1.170, 3.2.1.24 GH38 G ko:K01191,ko:K15524,ko:K16869 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Glycosyl hydrolases family 38 N-terminal domain
HMIFHPHL_02961 0.0 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
HMIFHPHL_02962 1.95e-250 - - - K - - - Transcriptional regulator
HMIFHPHL_02963 0.0 ypdD - - G - - - Glycosyl hydrolase family 92
HMIFHPHL_02964 1.09e-275 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HMIFHPHL_02965 3.76e-212 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HMIFHPHL_02966 0.0 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
HMIFHPHL_02967 0.0 - 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMIFHPHL_02968 1.71e-139 ypcB - - S - - - integral membrane protein
HMIFHPHL_02969 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
HMIFHPHL_02970 0.0 ypcG - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Domain of unknown function (DUF3502)
HMIFHPHL_02971 6.47e-213 lplC - - U ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMIFHPHL_02972 1.29e-231 ypdA - - U ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMIFHPHL_02973 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
HMIFHPHL_02974 3.87e-199 - - - K - - - helix_turn_helix, arabinose operon control protein
HMIFHPHL_02975 0.0 mdlA2 - - V ko:K06147 - ko00000,ko02000 ABC transporter
HMIFHPHL_02976 0.0 yknV - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HMIFHPHL_02977 2.99e-247 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
HMIFHPHL_02978 1.91e-201 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
HMIFHPHL_02979 6.96e-83 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
HMIFHPHL_02980 2.92e-233 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
HMIFHPHL_02981 1.23e-129 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
HMIFHPHL_02982 3.33e-113 srlM1 - - K - - - Glucitol operon activator protein (GutM)
HMIFHPHL_02983 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
HMIFHPHL_02984 9e-185 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
HMIFHPHL_02985 2.53e-209 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
HMIFHPHL_02986 4.99e-88 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HMIFHPHL_02987 7.82e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMIFHPHL_02988 4.04e-241 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HMIFHPHL_02989 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HMIFHPHL_02990 2.51e-103 - - - T - - - Universal stress protein family
HMIFHPHL_02991 7.43e-130 padR - - K - - - Virulence activator alpha C-term
HMIFHPHL_02992 2.71e-135 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
HMIFHPHL_02993 1.75e-186 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
HMIFHPHL_02994 3.66e-113 - - - K - - - Acetyltransferase (GNAT) domain
HMIFHPHL_02995 4.02e-203 degV1 - - S - - - DegV family
HMIFHPHL_02996 1.43e-80 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
HMIFHPHL_02997 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
HMIFHPHL_02999 2.76e-141 sip3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HMIFHPHL_03000 0.0 - - - - - - - -
HMIFHPHL_03002 2.88e-207 - - - S - - - Bacterial protein of unknown function (DUF916)
HMIFHPHL_03003 1.31e-143 - - - S - - - Cell surface protein
HMIFHPHL_03004 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HMIFHPHL_03005 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMIFHPHL_03006 2.37e-173 jag - - S ko:K06346 - ko00000 R3H domain protein
HMIFHPHL_03007 9.2e-306 - - - Q - - - Imidazolonepropionase and related amidohydrolases
HMIFHPHL_03008 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HMIFHPHL_03009 2.57e-157 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMIFHPHL_03010 3.08e-74 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HMIFHPHL_03011 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMIFHPHL_03012 8.19e-267 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HMIFHPHL_03013 3.82e-51 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
HMIFHPHL_03014 7.24e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMIFHPHL_03015 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMIFHPHL_03016 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMIFHPHL_03017 5.95e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HMIFHPHL_03018 1.68e-108 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMIFHPHL_03019 2.69e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMIFHPHL_03020 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HMIFHPHL_03021 3.44e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HMIFHPHL_03022 8.77e-317 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HMIFHPHL_03023 4.96e-289 yttB - - EGP - - - Major Facilitator
HMIFHPHL_03024 9e-184 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMIFHPHL_03025 1.88e-291 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HMIFHPHL_03027 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HMIFHPHL_03028 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HMIFHPHL_03029 6.65e-282 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HMIFHPHL_03030 3.49e-269 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
HMIFHPHL_03031 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
HMIFHPHL_03032 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HMIFHPHL_03033 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HMIFHPHL_03035 8.38e-184 - - - S - - - haloacid dehalogenase-like hydrolase
HMIFHPHL_03036 1.1e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HMIFHPHL_03037 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
HMIFHPHL_03038 3.21e-104 - - - S - - - Pyridoxamine 5'-phosphate oxidase
HMIFHPHL_03039 4.37e-43 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock protein domain
HMIFHPHL_03040 2.54e-50 - - - - - - - -
HMIFHPHL_03042 2.22e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HMIFHPHL_03043 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMIFHPHL_03044 3.55e-313 yycH - - S - - - YycH protein
HMIFHPHL_03045 3.54e-195 yycI - - S - - - YycH protein
HMIFHPHL_03046 1.71e-200 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
HMIFHPHL_03047 1.5e-253 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
HMIFHPHL_03048 6.08e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMIFHPHL_03049 1.38e-95 - - - M - - - Glycosyl hydrolases family 25
HMIFHPHL_03050 2.52e-07 - - - S - - - Bacteriophage A118-like holin, Hol118
HMIFHPHL_03055 4.57e-162 - - - LM - - - DNA recombination
HMIFHPHL_03057 4.34e-213 - - - L - - - Phage tail tape measure protein TP901
HMIFHPHL_03059 1.07e-43 - - - S - - - Phage tail tube protein
HMIFHPHL_03060 4.57e-29 - - - - - - - -
HMIFHPHL_03061 1.32e-44 - - - - - - - -
HMIFHPHL_03062 8.66e-32 - - - - - - - -
HMIFHPHL_03063 1.35e-22 - - - - - - - -
HMIFHPHL_03064 6.41e-141 - - - S - - - Phage capsid family
HMIFHPHL_03065 2.3e-70 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Clp protease
HMIFHPHL_03066 1.16e-126 - - - S - - - Phage portal protein
HMIFHPHL_03067 1.08e-222 - - - S - - - Phage Terminase
HMIFHPHL_03068 9.2e-16 - - - - - - - -
HMIFHPHL_03071 3.58e-34 - - - V - - - HNH nucleases
HMIFHPHL_03073 3.89e-52 - - - - - - - -
HMIFHPHL_03074 1.07e-19 - - - S - - - Domain of unknown function (DUF4145)
HMIFHPHL_03076 1.02e-72 - - - S - - - YopX protein
HMIFHPHL_03078 1.05e-22 - - - - - - - -
HMIFHPHL_03080 1.44e-52 - - - S - - - VRR_NUC
HMIFHPHL_03081 5.21e-165 - - - S ko:K06919 - ko00000 Virulence-associated protein E
HMIFHPHL_03082 8.23e-98 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
HMIFHPHL_03083 6.33e-28 - - - - - - - -
HMIFHPHL_03084 1.41e-93 - - - L - - - AAA domain
HMIFHPHL_03085 1.74e-217 - - - S - - - helicase activity
HMIFHPHL_03086 1.29e-52 - - - S - - - Siphovirus Gp157
HMIFHPHL_03092 1.53e-11 - - - - - - - -
HMIFHPHL_03093 5.72e-27 - - - - - - - -
HMIFHPHL_03100 1.63e-87 - - - S ko:K09705 - ko00000 Cupin superfamily (DUF985)
HMIFHPHL_03101 6.08e-139 - - - K - - - Putative ATP-dependent DNA helicase recG C-terminal
HMIFHPHL_03102 1.43e-66 - - - L - - - Belongs to the 'phage' integrase family
HMIFHPHL_03103 3.04e-241 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMIFHPHL_03105 4.48e-85 - - - - - - - -
HMIFHPHL_03106 5.73e-73 - - - - - - - -
HMIFHPHL_03107 3.52e-195 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
HMIFHPHL_03108 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
HMIFHPHL_03109 1.67e-182 - - - U ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMIFHPHL_03110 1.18e-193 - - - U ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMIFHPHL_03111 6.74e-316 - - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HMIFHPHL_03112 2.98e-269 msmK2 - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HMIFHPHL_03113 7.44e-186 - - - D - - - AAA domain
HMIFHPHL_03114 4.16e-46 - - - - - - - -
HMIFHPHL_03116 1.59e-49 - - - - - - - -
HMIFHPHL_03117 1.95e-45 ydaT - - - - - - -
HMIFHPHL_03119 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HMIFHPHL_03121 6.3e-200 - - - L ko:K07482 - ko00000 Integrase core domain
HMIFHPHL_03122 2.64e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
HMIFHPHL_03123 1.74e-72 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HMIFHPHL_03124 6.45e-98 - - - L - - - Transposase and inactivated derivatives, IS30 family
HMIFHPHL_03125 1.36e-245 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
HMIFHPHL_03126 1.02e-212 ugpA - - U ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMIFHPHL_03127 3.69e-193 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HMIFHPHL_03128 3.69e-312 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HMIFHPHL_03129 6.06e-156 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HMIFHPHL_03130 8.52e-60 - - - L - - - Transposase and inactivated derivatives, IS30 family
HMIFHPHL_03131 6.21e-62 - - - L - - - Transposase and inactivated derivatives, IS30 family
HMIFHPHL_03132 6.95e-70 - - - L - - - recombinase activity
HMIFHPHL_03133 1.15e-77 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HMIFHPHL_03134 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HMIFHPHL_03135 9.02e-82 kdpE - - KT ko:K02483,ko:K07667 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
HMIFHPHL_03136 3.9e-222 kdpD 2.7.13.3 - T ko:K07646 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HMIFHPHL_03137 2.47e-44 kdpC 3.6.3.12 - P ko:K01548 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HMIFHPHL_03138 0.0 kdpB 3.6.3.12 - P ko:K01547 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HMIFHPHL_03139 3.63e-217 kdpA - - P - - - Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HMIFHPHL_03141 1.41e-32 - - - T - - - Pfam Adenylate and Guanylate cyclase catalytic domain
HMIFHPHL_03143 8.73e-216 - - - M - - - transferase activity, transferring glycosyl groups
HMIFHPHL_03144 3.06e-245 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HMIFHPHL_03145 2.98e-177 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HMIFHPHL_03146 1.12e-198 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
HMIFHPHL_03147 1.92e-71 - - - - - - - -
HMIFHPHL_03148 4.8e-86 - - - - - - - -
HMIFHPHL_03150 5.45e-233 - - - L - - - Transposase and inactivated derivatives, IS30 family
HMIFHPHL_03151 1.14e-05 - - - S - - - Protein of unknown function (DUF3800)
HMIFHPHL_03152 2.71e-242 - - - L - - - Psort location Cytoplasmic, score
HMIFHPHL_03153 2.66e-84 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HMIFHPHL_03154 1.25e-209 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HMIFHPHL_03155 1.35e-256 - - - L - - - MobA MobL family protein
HMIFHPHL_03156 4.81e-36 - - - H - - - RibD C-terminal domain
HMIFHPHL_03157 0.0 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HMIFHPHL_03158 2.71e-232 traA - - L - - - MobA MobL family protein
HMIFHPHL_03159 6.52e-36 - - - - - - - -
HMIFHPHL_03160 9.29e-51 - - - - - - - -
HMIFHPHL_03161 2.22e-38 - - - S - - - protein conserved in bacteria
HMIFHPHL_03162 3.67e-37 - - - - - - - -
HMIFHPHL_03163 6.51e-64 repA - - S - - - Replication initiator protein A
HMIFHPHL_03164 1.62e-197 - - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
HMIFHPHL_03165 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HMIFHPHL_03166 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HMIFHPHL_03167 8.95e-26 - - - - - - - -
HMIFHPHL_03168 8.6e-20 - - - - - - - -
HMIFHPHL_03169 2.85e-53 - - - - - - - -
HMIFHPHL_03170 5.3e-110 - - - - - - - -
HMIFHPHL_03171 4.88e-59 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
HMIFHPHL_03172 4.06e-67 repA - - S - - - Replication initiator protein A
HMIFHPHL_03174 6.13e-127 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
HMIFHPHL_03176 5.32e-167 - - - S - - - haloacid dehalogenase-like hydrolase
HMIFHPHL_03177 4.6e-147 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HMIFHPHL_03178 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
HMIFHPHL_03180 7.16e-65 ysnF - - S - - - Heat induced stress protein YflT
HMIFHPHL_03182 7.04e-11 - - - M - - - Lysin motif
HMIFHPHL_03184 4.97e-127 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
HMIFHPHL_03187 7.32e-46 - - - - - - - -
HMIFHPHL_03188 5.82e-124 tnpR1 - - L - - - Resolvase, N terminal domain
HMIFHPHL_03189 4.88e-200 is18 - - L - - - Integrase core domain
HMIFHPHL_03190 2.48e-52 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
HMIFHPHL_03191 1.73e-174 - - - L - - - Replication protein

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)