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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
OIOLDKHP_00001	4.83e-259	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
OIOLDKHP_00002	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
OIOLDKHP_00004	4.32e-103	-	-	-	F	-	-	-	Hydrolase, nudix family
OIOLDKHP_00005	1.34e-73	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
OIOLDKHP_00006	2.33e-87	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
OIOLDKHP_00007	6.24e-11	-	2.3.1.178	-	M	ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	ko00000,ko00001,ko00002,ko01000	phosphinothricin N-acetyltransferase activity
OIOLDKHP_00008	5.59e-71	-	-	-	M	-	-	-	GNAT acetyltransferase
OIOLDKHP_00010	3.42e-245	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
OIOLDKHP_00011	2.77e-84	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
OIOLDKHP_00012	4.36e-236	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
OIOLDKHP_00013	1.17e-98	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
OIOLDKHP_00014	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
OIOLDKHP_00015	1.58e-143	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
OIOLDKHP_00016	1.77e-158	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
OIOLDKHP_00017	1.64e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF441)
OIOLDKHP_00018	8.84e-76	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OIOLDKHP_00019	2.3e-127	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
OIOLDKHP_00020	3.83e-79	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OIOLDKHP_00021	9.74e-76	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OIOLDKHP_00022	6.85e-49	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OIOLDKHP_00023	6.04e-275	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OIOLDKHP_00024	4.03e-102	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OIOLDKHP_00025	3.63e-155	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
OIOLDKHP_00026	7.73e-226	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
OIOLDKHP_00027	2.75e-124	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
OIOLDKHP_00029	4.7e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
OIOLDKHP_00030	1.55e-37	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
OIOLDKHP_00031	3.02e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
OIOLDKHP_00038	7.66e-80	-	-	-	H	-	-	-	Methyltransferase domain
OIOLDKHP_00039	2.27e-90	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
OIOLDKHP_00040	1.58e-51	-	-	-	M	-	-	-	Acetyltransferase (GNAT) family
OIOLDKHP_00042	1.15e-29	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
OIOLDKHP_00043	2.29e-51	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
OIOLDKHP_00044	2.66e-106	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
OIOLDKHP_00045	5.99e-40	-	-	-	S	-	-	-	CHY zinc finger
OIOLDKHP_00046	7.27e-53	ywnA	-	-	K	-	-	-	Transcriptional regulator
OIOLDKHP_00047	8.23e-105	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
OIOLDKHP_00050	2.66e-156	-	-	-	M	-	-	-	Glycosyl transferases group 1
OIOLDKHP_00051	4.57e-79	-	-	-	M	-	-	-	Glycosyl transferases group 1
OIOLDKHP_00052	5.49e-208	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OIOLDKHP_00053	3.08e-183	-	5.1.3.6	-	GM	ko:K08679	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	RmlD substrate binding domain
OIOLDKHP_00054	8.45e-125	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
OIOLDKHP_00055	4.83e-72	-	-	-	M	-	-	-	Glycosyl transferases group 1
OIOLDKHP_00056	4.05e-146	-	-	-	S	-	-	-	Glycosyltransferase WbsX
OIOLDKHP_00057	6.8e-64	-	-	-	-	-	-	-	-
OIOLDKHP_00059	3.22e-71	-	-	-	M	-	-	-	Glycosyltransferase like family 2
OIOLDKHP_00060	1.86e-45	rfbF	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
OIOLDKHP_00061	4.36e-91	-	-	-	M	-	-	-	Glycosyltransferase Family 4
OIOLDKHP_00062	2.32e-94	-	-	-	M	-	-	-	glycosyl transferase group 1
OIOLDKHP_00063	7.95e-98	-	-	-	M	-	-	-	glycosyl transferase group 1
OIOLDKHP_00064	3.26e-152	-	-	-	M	-	-	-	Glycosyl transferases group 1
OIOLDKHP_00065	1.52e-35	-	-	-	S	ko:K19429	-	ko00000,ko01000	Bacterial transferase hexapeptide (six repeats)
OIOLDKHP_00066	1.26e-99	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
OIOLDKHP_00067	1.51e-210	epsN	-	-	M	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
OIOLDKHP_00068	1.75e-276	capD	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
OIOLDKHP_00069	5.73e-82	-	-	-	D	-	-	-	AAA domain
OIOLDKHP_00070	8.89e-59	-	-	-	M	-	-	-	Chain length determinant protein
OIOLDKHP_00071	3e-53	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Protease synthase and sporulation negative regulatory protein pai 1
OIOLDKHP_00072	9.71e-225	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
OIOLDKHP_00073	3.87e-82	-	-	-	-	-	-	-	-
OIOLDKHP_00074	4.55e-105	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
OIOLDKHP_00075	3.53e-144	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
OIOLDKHP_00076	1.84e-76	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
OIOLDKHP_00077	4e-240	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
OIOLDKHP_00078	5.92e-33	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
OIOLDKHP_00079	2.63e-265	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
OIOLDKHP_00081	4.18e-80	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
OIOLDKHP_00082	1.11e-68	-	-	-	S	-	-	-	Membrane
OIOLDKHP_00083	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
OIOLDKHP_00084	1.82e-77	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
OIOLDKHP_00085	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
OIOLDKHP_00086	8.4e-66	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
OIOLDKHP_00087	4.69e-36	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
OIOLDKHP_00088	4.61e-153	-	-	-	T	-	-	-	diguanylate cyclase activity
OIOLDKHP_00089	8.13e-276	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
OIOLDKHP_00090	2.81e-91	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
OIOLDKHP_00091	4.94e-255	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
OIOLDKHP_00092	3.66e-197	-	-	-	S	-	-	-	Protein conserved in bacteria
OIOLDKHP_00093	1.2e-43	-	-	-	S	-	-	-	Protein conserved in bacteria
OIOLDKHP_00094	1.26e-235	-	-	-	-	-	-	-	-
OIOLDKHP_00095	7.49e-161	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
OIOLDKHP_00096	1.76e-36	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
OIOLDKHP_00098	7.17e-183	pbuO_1	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
OIOLDKHP_00099	1.25e-196	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
OIOLDKHP_00100	3.48e-134	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
OIOLDKHP_00101	9.22e-121	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
OIOLDKHP_00102	4.93e-276	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
OIOLDKHP_00103	1.09e-253	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
OIOLDKHP_00104	5.29e-178	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
OIOLDKHP_00105	1.06e-243	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
OIOLDKHP_00106	2.32e-203	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
OIOLDKHP_00107	3.05e-48	-	-	-	M	-	-	-	LysM domain
OIOLDKHP_00108	1.38e-25	-	-	-	P	-	-	-	Rhodanese Homology Domain
OIOLDKHP_00109	1.8e-67	-	-	-	M	-	-	-	LysM domain protein
OIOLDKHP_00110	7.86e-116	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
OIOLDKHP_00111	4.26e-108	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
OIOLDKHP_00113	8.05e-91	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
OIOLDKHP_00114	1.84e-130	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OIOLDKHP_00115	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OIOLDKHP_00116	1.14e-91	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
OIOLDKHP_00117	5.69e-104	ylmH	-	-	S	-	-	-	S4 domain protein
OIOLDKHP_00118	8.19e-27	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
OIOLDKHP_00119	8.14e-43	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
OIOLDKHP_00120	1.29e-228	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OIOLDKHP_00121	6.07e-240	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
OIOLDKHP_00122	6.44e-76	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
OIOLDKHP_00123	8.63e-195	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OIOLDKHP_00124	2.97e-233	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OIOLDKHP_00125	3.64e-172	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OIOLDKHP_00126	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
OIOLDKHP_00127	1.05e-13	ftsL	-	-	D	-	-	-	Essential cell division protein
OIOLDKHP_00128	3.67e-180	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
OIOLDKHP_00129	3.76e-82	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
OIOLDKHP_00131	5.43e-196	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
OIOLDKHP_00133	4.54e-124	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
OIOLDKHP_00134	3.24e-138	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
OIOLDKHP_00135	2.01e-115	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
OIOLDKHP_00136	3.02e-122	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
OIOLDKHP_00137	7.95e-163	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
OIOLDKHP_00138	1.77e-98	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
OIOLDKHP_00139	9.34e-71	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
OIOLDKHP_00140	1.64e-121	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
OIOLDKHP_00141	3.34e-207	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
OIOLDKHP_00142	1.96e-29	-	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
OIOLDKHP_00143	1.31e-101	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
OIOLDKHP_00144	1.97e-168	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
OIOLDKHP_00145	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
OIOLDKHP_00146	1.44e-248	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OIOLDKHP_00147	5.87e-204	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
OIOLDKHP_00148	1.4e-224	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OIOLDKHP_00149	1.81e-72	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
OIOLDKHP_00150	5.9e-130	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OIOLDKHP_00151	4.14e-31	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
OIOLDKHP_00152	7.05e-242	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
OIOLDKHP_00154	6.35e-97	uspA	-	-	T	-	-	-	universal stress protein
OIOLDKHP_00155	4.17e-70	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
OIOLDKHP_00156	5.17e-253	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
OIOLDKHP_00157	1.2e-157	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
OIOLDKHP_00159	5.95e-96	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
OIOLDKHP_00160	3e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
OIOLDKHP_00161	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
OIOLDKHP_00162	0.0	-	-	-	S	-	-	-	membrane
OIOLDKHP_00163	4.3e-104	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OIOLDKHP_00164	1.17e-266	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
OIOLDKHP_00165	3.93e-127	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
OIOLDKHP_00166	3.04e-179	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
OIOLDKHP_00168	1.68e-22	-	-	-	-	-	-	-	-
OIOLDKHP_00169	4.8e-253	oatA	-	-	I	-	-	-	Acyltransferase
OIOLDKHP_00170	9.11e-270	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OIOLDKHP_00171	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
OIOLDKHP_00172	9.92e-178	-	1.1.1.29	-	C	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OIOLDKHP_00175	8.44e-52	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
OIOLDKHP_00176	4.41e-94	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OIOLDKHP_00177	3.55e-79	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
OIOLDKHP_00178	5.23e-54	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
OIOLDKHP_00179	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
OIOLDKHP_00180	3.86e-20	cvpA	-	-	S	-	-	-	Colicin V production protein
OIOLDKHP_00181	3.67e-17	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OIOLDKHP_00182	4.23e-44	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
OIOLDKHP_00183	1.57e-78	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OIOLDKHP_00184	2.44e-49	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
OIOLDKHP_00185	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OIOLDKHP_00186	1.06e-236	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
OIOLDKHP_00187	1.25e-153	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
OIOLDKHP_00188	3.5e-18	-	-	-	-	-	-	-	-
OIOLDKHP_00189	6.8e-185	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OIOLDKHP_00190	4.44e-85	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
OIOLDKHP_00191	4.95e-311	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
OIOLDKHP_00192	3.54e-150	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
OIOLDKHP_00193	2.92e-264	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
OIOLDKHP_00195	3.61e-79	uspA3	-	-	T	-	-	-	universal stress protein
OIOLDKHP_00197	1.06e-20	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
OIOLDKHP_00198	5.96e-263	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
OIOLDKHP_00199	2.88e-231	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OIOLDKHP_00200	1.45e-193	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
OIOLDKHP_00201	2.19e-91	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
OIOLDKHP_00202	1.41e-287	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OIOLDKHP_00203	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OIOLDKHP_00204	4.38e-256	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
OIOLDKHP_00205	1.84e-203	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OIOLDKHP_00206	2.09e-111	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OIOLDKHP_00207	7.25e-85	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
OIOLDKHP_00208	5.2e-116	ymfI	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
OIOLDKHP_00209	5.66e-184	ymfH	-	-	S	-	-	-	Peptidase M16
OIOLDKHP_00210	1.2e-135	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
OIOLDKHP_00211	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
OIOLDKHP_00212	2.62e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
OIOLDKHP_00213	2.88e-124	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
OIOLDKHP_00214	8.29e-83	-	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
OIOLDKHP_00215	1.61e-207	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
OIOLDKHP_00216	7e-250	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OIOLDKHP_00217	8.5e-24	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
OIOLDKHP_00218	1.53e-163	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
OIOLDKHP_00219	1.59e-38	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
OIOLDKHP_00220	1.1e-284	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIOLDKHP_00221	1.16e-84	ybbR	-	-	S	-	-	-	YbbR-like protein
OIOLDKHP_00222	1.95e-162	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OIOLDKHP_00223	3.92e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
OIOLDKHP_00224	4.26e-146	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
OIOLDKHP_00225	4.75e-90	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
OIOLDKHP_00226	1e-72	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
OIOLDKHP_00227	7.01e-181	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
OIOLDKHP_00228	1.52e-134	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OIOLDKHP_00229	1.68e-148	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
OIOLDKHP_00230	7.86e-53	-	-	-	-	-	-	-	-
OIOLDKHP_00231	4.3e-91	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
OIOLDKHP_00232	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
OIOLDKHP_00233	1.19e-32	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
OIOLDKHP_00234	6.32e-224	eriC	-	-	P	ko:K03281	-	ko00000	chloride
OIOLDKHP_00235	5.39e-189	-	-	-	E	-	-	-	Major Facilitator Superfamily
OIOLDKHP_00236	8.04e-212	yclK	-	-	T	-	-	-	Histidine kinase
OIOLDKHP_00237	1.95e-134	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
OIOLDKHP_00238	5.56e-151	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIOLDKHP_00239	4.33e-298	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
OIOLDKHP_00240	9.95e-165	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
OIOLDKHP_00241	1.99e-264	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
OIOLDKHP_00242	1.19e-231	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OIOLDKHP_00243	1.59e-174	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
OIOLDKHP_00245	2.07e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
OIOLDKHP_00246	5.86e-191	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
OIOLDKHP_00247	9.11e-195	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
OIOLDKHP_00248	7.15e-161	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
OIOLDKHP_00249	4.6e-101	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
OIOLDKHP_00250	1.23e-107	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
OIOLDKHP_00251	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
OIOLDKHP_00252	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
OIOLDKHP_00253	1.47e-50	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
OIOLDKHP_00254	3.42e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
OIOLDKHP_00255	3.71e-09	-	-	-	S	-	-	-	Putative adhesin
OIOLDKHP_00256	8.46e-23	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
OIOLDKHP_00259	1.68e-295	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OIOLDKHP_00260	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
OIOLDKHP_00261	3.27e-130	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
OIOLDKHP_00262	2.58e-211	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
OIOLDKHP_00263	3.85e-153	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
OIOLDKHP_00264	1.8e-132	potC	-	-	U	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
OIOLDKHP_00265	1.19e-201	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
OIOLDKHP_00266	1.12e-168	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
OIOLDKHP_00267	9.74e-147	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
OIOLDKHP_00268	1.93e-138	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
OIOLDKHP_00269	2.49e-87	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
OIOLDKHP_00270	6.58e-70	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
OIOLDKHP_00271	6.13e-286	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OIOLDKHP_00272	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
OIOLDKHP_00273	2.22e-131	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
OIOLDKHP_00274	1.12e-72	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
OIOLDKHP_00275	3.04e-59	-	-	-	C	-	-	-	Flavodoxin
OIOLDKHP_00276	2.91e-76	yphH	-	-	S	-	-	-	Cupin domain
OIOLDKHP_00277	3.59e-60	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
OIOLDKHP_00278	3.1e-178	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
OIOLDKHP_00279	1.81e-136	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
OIOLDKHP_00280	1.87e-188	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIOLDKHP_00281	5.23e-119	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
OIOLDKHP_00282	3.22e-168	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
OIOLDKHP_00283	2.84e-107	-	-	-	C	-	-	-	nitroreductase
OIOLDKHP_00284	2.51e-105	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
OIOLDKHP_00285	1.16e-136	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
OIOLDKHP_00286	6.07e-214	npr	1.11.1.1	-	S	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
OIOLDKHP_00287	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
OIOLDKHP_00289	6.24e-192	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIOLDKHP_00290	1.02e-73	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
OIOLDKHP_00291	2.56e-163	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
OIOLDKHP_00292	6.63e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF4256)
OIOLDKHP_00295	1.49e-223	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
OIOLDKHP_00296	6.13e-212	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
OIOLDKHP_00297	5.48e-230	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OIOLDKHP_00298	4.36e-291	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
OIOLDKHP_00299	6.7e-187	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
OIOLDKHP_00300	2.36e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
OIOLDKHP_00301	1.23e-79	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
OIOLDKHP_00302	2.52e-17	-	-	-	-	-	-	-	-
OIOLDKHP_00303	3.81e-37	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
OIOLDKHP_00304	2.79e-281	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
OIOLDKHP_00305	1.39e-111	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
OIOLDKHP_00306	4.7e-192	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
OIOLDKHP_00307	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
OIOLDKHP_00308	2.33e-57	cps3F	-	-	-	-	-	-	-
OIOLDKHP_00309	2.22e-108	-	-	-	S	-	-	-	Membrane
OIOLDKHP_00310	0.0	-	-	-	E	-	-	-	Amino acid permease
OIOLDKHP_00311	1.69e-291	cadA	-	-	P	-	-	-	P-type ATPase
OIOLDKHP_00312	2.47e-146	degV	-	-	S	-	-	-	EDD domain protein, DegV family
OIOLDKHP_00313	5.86e-189	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
OIOLDKHP_00314	1.68e-69	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
OIOLDKHP_00315	3.23e-36	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
OIOLDKHP_00316	6.07e-186	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OIOLDKHP_00317	1.48e-171	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
OIOLDKHP_00318	2.28e-92	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
OIOLDKHP_00319	1.18e-207	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
OIOLDKHP_00320	6.29e-21	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
OIOLDKHP_00321	1.04e-284	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
OIOLDKHP_00322	6.86e-159	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
OIOLDKHP_00323	1.39e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1634)
OIOLDKHP_00324	2.82e-147	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
OIOLDKHP_00325	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
OIOLDKHP_00326	8.29e-143	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OIOLDKHP_00327	5.85e-168	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OIOLDKHP_00328	2.17e-35	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
OIOLDKHP_00329	1.44e-10	-	-	-	K	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
OIOLDKHP_00330	7.39e-104	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
OIOLDKHP_00331	1.03e-110	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
OIOLDKHP_00332	3.93e-80	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
OIOLDKHP_00333	8.77e-205	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OIOLDKHP_00334	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
OIOLDKHP_00335	1.49e-121	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
OIOLDKHP_00336	7.08e-105	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OIOLDKHP_00337	1.13e-68	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
OIOLDKHP_00338	3.51e-158	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
OIOLDKHP_00339	3.75e-200	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
OIOLDKHP_00340	0.0	ydaO	-	-	E	-	-	-	amino acid
OIOLDKHP_00341	0.0	-	-	-	P	ko:K12952	-	ko00000,ko01000	COG COG0474 Cation transport ATPase
OIOLDKHP_00342	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
OIOLDKHP_00343	1.7e-46	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OIOLDKHP_00344	4.03e-41	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
OIOLDKHP_00345	5.32e-127	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OIOLDKHP_00346	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
OIOLDKHP_00347	2.51e-206	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OIOLDKHP_00348	1.9e-19	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
OIOLDKHP_00349	3.7e-88	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
OIOLDKHP_00350	2.82e-178	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
OIOLDKHP_00351	6.03e-105	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
OIOLDKHP_00352	9.92e-121	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OIOLDKHP_00353	3.85e-52	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
OIOLDKHP_00354	3.76e-104	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
OIOLDKHP_00355	2.18e-83	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OIOLDKHP_00356	4.16e-39	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
OIOLDKHP_00357	6.62e-126	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OIOLDKHP_00358	3.8e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OIOLDKHP_00359	5.45e-268	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OIOLDKHP_00360	2.23e-80	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
OIOLDKHP_00361	1.11e-96	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
OIOLDKHP_00362	5.56e-37	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
OIOLDKHP_00363	1.81e-58	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
OIOLDKHP_00364	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OIOLDKHP_00365	1.1e-203	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OIOLDKHP_00366	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OIOLDKHP_00367	7.33e-71	-	-	-	-	-	-	-	-
OIOLDKHP_00368	2.18e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
OIOLDKHP_00369	2.21e-97	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OIOLDKHP_00370	9.98e-150	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
OIOLDKHP_00371	2.58e-88	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OIOLDKHP_00372	3.13e-109	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
OIOLDKHP_00373	3.08e-16	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
OIOLDKHP_00374	3.3e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
OIOLDKHP_00375	1.24e-67	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
OIOLDKHP_00376	1.88e-138	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIOLDKHP_00377	3.45e-73	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OIOLDKHP_00378	2.26e-263	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
OIOLDKHP_00379	7.38e-313	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIOLDKHP_00380	1.38e-195	yacL	-	-	S	-	-	-	domain protein
OIOLDKHP_00381	1.32e-282	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OIOLDKHP_00382	3.38e-95	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
OIOLDKHP_00383	1.17e-25	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
OIOLDKHP_00384	5.18e-281	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
OIOLDKHP_00385	2.56e-45	-	-	-	S	-	-	-	Enterocin A Immunity
OIOLDKHP_00386	2.04e-109	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OIOLDKHP_00387	2.13e-163	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
OIOLDKHP_00388	2.66e-148	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OIOLDKHP_00390	1.13e-54	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
OIOLDKHP_00391	5.71e-316	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
OIOLDKHP_00392	1.86e-165	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
OIOLDKHP_00393	2.18e-307	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OIOLDKHP_00394	3.32e-113	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
OIOLDKHP_00395	9.25e-124	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
OIOLDKHP_00396	4.28e-115	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OIOLDKHP_00399	4.29e-260	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
OIOLDKHP_00400	3.31e-282	-	-	-	L	-	-	-	Probable transposase
OIOLDKHP_00401	2.73e-74	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
OIOLDKHP_00402	5.8e-110	-	-	-	S	-	-	-	hydrolase
OIOLDKHP_00403	3.45e-261	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
OIOLDKHP_00404	4.07e-109	-	-	-	F	-	-	-	glutamine amidotransferase
OIOLDKHP_00405	1.8e-32	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
OIOLDKHP_00406	3.53e-64	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
OIOLDKHP_00407	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
OIOLDKHP_00410	4.42e-253	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OIOLDKHP_00411	3.9e-240	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OIOLDKHP_00412	5.02e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
OIOLDKHP_00413	4.53e-79	-	-	-	-	-	-	-	-
OIOLDKHP_00414	5.29e-317	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
OIOLDKHP_00416	2.54e-98	-	-	-	S	-	-	-	Cell surface protein
OIOLDKHP_00419	1.01e-229	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
OIOLDKHP_00420	2.19e-81	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
OIOLDKHP_00421	8.1e-225	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
OIOLDKHP_00422	1.32e-282	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
OIOLDKHP_00423	1.5e-40	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
OIOLDKHP_00424	1.53e-181	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OIOLDKHP_00426	5e-64	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
OIOLDKHP_00427	1.84e-116	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
OIOLDKHP_00428	1.63e-196	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
OIOLDKHP_00429	1.8e-56	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
OIOLDKHP_00430	4.74e-74	-	-	-	-	-	-	-	-
OIOLDKHP_00431	3.8e-53	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
OIOLDKHP_00432	3.84e-31	-	-	-	S	-	-	-	Cytochrome B5
OIOLDKHP_00434	7.94e-80	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
OIOLDKHP_00435	6.34e-242	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OIOLDKHP_00436	9.74e-126	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
OIOLDKHP_00437	1.42e-135	yueF	-	-	S	-	-	-	AI-2E family transporter
OIOLDKHP_00438	3.8e-201	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
OIOLDKHP_00439	1.97e-146	tagH	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
OIOLDKHP_00440	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OIOLDKHP_00441	3.67e-40	-	-	-	-	-	-	-	-
OIOLDKHP_00442	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
OIOLDKHP_00443	1.1e-281	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
OIOLDKHP_00444	3.21e-139	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
OIOLDKHP_00445	7.51e-226	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OIOLDKHP_00446	1.26e-207	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIOLDKHP_00447	1.72e-252	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
OIOLDKHP_00448	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
OIOLDKHP_00449	1.34e-130	-	-	-	G	-	-	-	MucBP domain
OIOLDKHP_00450	4.34e-32	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
OIOLDKHP_00451	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
OIOLDKHP_00452	1.5e-22	-	-	-	-	-	-	-	-
OIOLDKHP_00453	5.69e-49	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
OIOLDKHP_00454	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OIOLDKHP_00455	1.27e-203	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
OIOLDKHP_00456	3.2e-164	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
OIOLDKHP_00457	8.79e-166	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OIOLDKHP_00458	3.45e-36	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
OIOLDKHP_00459	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
OIOLDKHP_00460	6.22e-80	-	-	-	-	-	-	-	-
OIOLDKHP_00462	2.55e-26	recD2_2	3.1.11.5	-	L	ko:K01144	-	ko00000,ko01000	PIF1-like helicase
OIOLDKHP_00464	9.35e-63	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
OIOLDKHP_00466	6.71e-110	-	-	-	S	-	-	-	overlaps another CDS with the same product name
OIOLDKHP_00467	2.25e-156	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
OIOLDKHP_00468	3.51e-124	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
OIOLDKHP_00469	1.41e-43	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
OIOLDKHP_00470	1.25e-19	-	-	-	S	-	-	-	Belongs to the UPF0173 family
OIOLDKHP_00471	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
OIOLDKHP_00472	3.47e-98	-	-	-	F	-	-	-	Phosphorylase superfamily
OIOLDKHP_00473	1.82e-33	-	-	-	-	-	-	-	-
OIOLDKHP_00474	8.27e-141	dkgB	-	-	S	-	-	-	reductase
OIOLDKHP_00475	6.97e-27	rimL	1.1.1.25	-	J	ko:K00014,ko:K03817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OIOLDKHP_00476	2.25e-216	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIOLDKHP_00477	7.9e-257	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OIOLDKHP_00478	3.43e-72	-	-	-	EGP	-	-	-	Transmembrane secretion effector
OIOLDKHP_00479	7.37e-175	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
OIOLDKHP_00480	1.26e-68	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
OIOLDKHP_00481	6.82e-235	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OIOLDKHP_00482	4.5e-135	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
OIOLDKHP_00483	4.72e-160	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OIOLDKHP_00484	3.5e-190	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
OIOLDKHP_00485	3.94e-249	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
OIOLDKHP_00486	1.93e-253	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
OIOLDKHP_00488	3.01e-193	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
OIOLDKHP_00489	3.59e-148	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OIOLDKHP_00490	5.97e-63	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
OIOLDKHP_00491	5.51e-171	arcT	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
OIOLDKHP_00492	1.1e-114	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
OIOLDKHP_00493	5.45e-31	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
OIOLDKHP_00494	2.66e-169	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
OIOLDKHP_00495	4.87e-112	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OIOLDKHP_00496	4.02e-130	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
OIOLDKHP_00497	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIOLDKHP_00498	3.93e-163	-	-	-	-	-	-	-	-
OIOLDKHP_00499	1.67e-188	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
OIOLDKHP_00500	1.49e-54	-	-	-	ET	-	-	-	Bacterial extracellular solute-binding proteins, family 3
OIOLDKHP_00501	2.39e-41	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
OIOLDKHP_00502	2.58e-130	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
OIOLDKHP_00503	6.86e-105	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
OIOLDKHP_00504	1.13e-128	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
OIOLDKHP_00505	1.15e-216	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
OIOLDKHP_00506	1.12e-159	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OIOLDKHP_00507	0.0	-	-	-	L	-	-	-	DNA helicase
OIOLDKHP_00510	7.44e-51	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OIOLDKHP_00511	3.64e-135	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OIOLDKHP_00512	6.61e-224	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
OIOLDKHP_00513	2.67e-158	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
OIOLDKHP_00514	3.61e-43	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
OIOLDKHP_00515	3.33e-97	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
OIOLDKHP_00516	2.23e-209	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OIOLDKHP_00517	1.43e-164	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OIOLDKHP_00518	2.76e-91	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
OIOLDKHP_00519	8.75e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
OIOLDKHP_00520	1.13e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
OIOLDKHP_00521	1.15e-187	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
OIOLDKHP_00522	1.69e-153	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
OIOLDKHP_00523	3.19e-192	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
OIOLDKHP_00524	6.65e-103	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	sugar-binding domain protein
OIOLDKHP_00525	8.66e-120	baeS	-	-	T	-	-	-	Histidine kinase
OIOLDKHP_00526	1.51e-101	yfiK	-	-	K	ko:K02479	-	ko00000,ko02022	Bacterial regulatory proteins, luxR family
OIOLDKHP_00527	1.82e-149	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
OIOLDKHP_00528	1.22e-89	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
OIOLDKHP_00529	1.29e-51	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OIOLDKHP_00530	1.24e-43	-	-	-	K	-	-	-	MerR HTH family regulatory protein
OIOLDKHP_00531	1.41e-246	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
OIOLDKHP_00532	5.63e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
OIOLDKHP_00533	3.58e-51	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
OIOLDKHP_00534	9.45e-76	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
OIOLDKHP_00535	5.62e-92	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
OIOLDKHP_00536	7.88e-116	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
OIOLDKHP_00537	1.9e-71	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
OIOLDKHP_00538	4.12e-110	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
OIOLDKHP_00539	5.71e-28	-	-	-	-	-	-	-	-
OIOLDKHP_00540	2.33e-19	-	-	-	M	-	-	-	Glycosyltransferase like family 2
OIOLDKHP_00541	7.12e-68	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
OIOLDKHP_00542	2.17e-74	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
OIOLDKHP_00543	1.2e-144	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
OIOLDKHP_00544	3.91e-229	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
OIOLDKHP_00545	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
OIOLDKHP_00546	2.23e-270	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
OIOLDKHP_00547	1.77e-155	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
OIOLDKHP_00548	2.31e-94	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
OIOLDKHP_00549	7.67e-71	ymdB	-	-	L	-	-	-	phosphatase homologous to the C-terminal domain of histone macroH2A1
OIOLDKHP_00550	6.71e-32	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
OIOLDKHP_00551	5.29e-59	yyaT	-	-	K	ko:K02348	-	ko00000	protein acetylation
OIOLDKHP_00552	1.29e-11	-	-	-	-	-	-	-	-
OIOLDKHP_00553	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
OIOLDKHP_00554	1.53e-278	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
OIOLDKHP_00555	3.14e-44	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
OIOLDKHP_00556	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
OIOLDKHP_00557	2.72e-278	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OIOLDKHP_00558	5.55e-188	-	-	-	G	-	-	-	Transporter, major facilitator family protein
OIOLDKHP_00559	3.59e-114	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
OIOLDKHP_00560	5.29e-191	hpk31	-	-	T	-	-	-	Histidine kinase
OIOLDKHP_00561	1.21e-145	vanR	-	-	K	-	-	-	response regulator
OIOLDKHP_00562	2.23e-105	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
OIOLDKHP_00563	9.18e-116	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
OIOLDKHP_00564	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OIOLDKHP_00565	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
OIOLDKHP_00566	2.95e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OIOLDKHP_00567	4.06e-30	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
OIOLDKHP_00568	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OIOLDKHP_00569	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OIOLDKHP_00570	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
OIOLDKHP_00571	6.91e-73	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
OIOLDKHP_00573	6.07e-152	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
OIOLDKHP_00574	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
OIOLDKHP_00575	1.12e-198	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
OIOLDKHP_00576	5.09e-233	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
OIOLDKHP_00577	1.38e-165	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
OIOLDKHP_00592	1.25e-273	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
OIOLDKHP_00593	6.03e-96	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
OIOLDKHP_00596	3.7e-111	-	-	-	S	-	-	-	AAA domain
OIOLDKHP_00597	6.86e-25	-	-	-	S	-	-	-	TerB N-terminal domain
OIOLDKHP_00598	3.05e-69	-	-	-	S	-	-	-	sequence-specific DNA binding
OIOLDKHP_00599	2.76e-23	-	-	-	-	-	-	-	-
OIOLDKHP_00605	8.36e-31	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
OIOLDKHP_00607	8.9e-96	-	-	-	S	-	-	-	AAA domain
OIOLDKHP_00608	5.52e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
OIOLDKHP_00609	9.9e-120	-	-	-	S	-	-	-	Putative HNHc nuclease
OIOLDKHP_00610	6.71e-19	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
OIOLDKHP_00611	2.79e-47	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
OIOLDKHP_00612	1.04e-157	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
OIOLDKHP_00614	1.66e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
OIOLDKHP_00616	1.03e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
OIOLDKHP_00621	6.94e-38	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
OIOLDKHP_00625	3.41e-52	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
OIOLDKHP_00626	3.72e-223	-	-	-	S	-	-	-	Pfam:Terminase_3C
OIOLDKHP_00627	3.09e-176	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
OIOLDKHP_00628	5.48e-112	-	-	-	S	-	-	-	Phage minor capsid protein 2
OIOLDKHP_00630	9.27e-30	-	-	-	S	-	-	-	Phage minor structural protein GP20
OIOLDKHP_00631	1.01e-123	-	-	-	S	-	-	-	T=7 icosahedral viral capsid
OIOLDKHP_00633	9.25e-40	-	-	-	S	-	-	-	Minor capsid protein
OIOLDKHP_00636	3.72e-50	-	-	-	N	-	-	-	domain, Protein
OIOLDKHP_00638	6.29e-49	-	-	-	S	-	-	-	Bacteriophage Gp15 protein
OIOLDKHP_00639	6.46e-114	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
OIOLDKHP_00641	7.73e-118	-	-	-	M	-	-	-	Prophage endopeptidase tail
OIOLDKHP_00643	4.72e-29	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
OIOLDKHP_00646	2.55e-65	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
OIOLDKHP_00647	2.85e-119	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
OIOLDKHP_00648	1.08e-117	dedA	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
OIOLDKHP_00649	4.54e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
OIOLDKHP_00650	1.19e-145	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
OIOLDKHP_00651	4.29e-77	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
OIOLDKHP_00652	9.2e-73	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
OIOLDKHP_00653	1.22e-238	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
OIOLDKHP_00654	1.41e-123	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
OIOLDKHP_00658	7.13e-18	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
OIOLDKHP_00659	4.34e-36	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
OIOLDKHP_00660	7.88e-122	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
OIOLDKHP_00661	5.53e-153	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
OIOLDKHP_00662	4.05e-130	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OIOLDKHP_00663	4e-153	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
OIOLDKHP_00664	4.81e-54	-	-	-	S	-	-	-	VanZ like family
OIOLDKHP_00665	1.26e-202	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
OIOLDKHP_00666	9.17e-219	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
OIOLDKHP_00668	6.19e-10	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OIOLDKHP_00670	2.81e-95	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OIOLDKHP_00671	1.38e-46	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
OIOLDKHP_00672	6.12e-83	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
OIOLDKHP_00673	4.88e-54	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
OIOLDKHP_00674	5.45e-107	-	-	-	S	-	-	-	membrane
OIOLDKHP_00675	1.39e-100	-	-	-	S	-	-	-	VIT family
OIOLDKHP_00676	4.94e-188	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
OIOLDKHP_00677	2.26e-73	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
OIOLDKHP_00678	6.43e-149	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OIOLDKHP_00679	2.14e-146	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OIOLDKHP_00680	1.35e-154	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
OIOLDKHP_00681	2.58e-150	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
OIOLDKHP_00682	1.07e-125	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
OIOLDKHP_00683	5.02e-54	yjbH	-	-	Q	-	-	-	Thioredoxin
OIOLDKHP_00684	2.49e-288	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
OIOLDKHP_00685	1.87e-85	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
OIOLDKHP_00686	6.97e-63	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
OIOLDKHP_00687	2.75e-144	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
OIOLDKHP_00688	1.41e-26	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
OIOLDKHP_00690	1.54e-116	XK27_05145	-	-	L	-	-	-	Belongs to the 'phage' integrase family
OIOLDKHP_00691	4.88e-19	-	-	-	E	-	-	-	Zn peptidase
OIOLDKHP_00692	9.08e-38	-	-	-	S	-	-	-	sequence-specific DNA binding
OIOLDKHP_00693	1.84e-06	-	-	-	K	ko:K18831,ko:K21498	-	ko00000,ko02048,ko03000	addiction module antidote protein HigA
OIOLDKHP_00695	7.65e-54	-	-	-	S	-	-	-	AntA/AntB antirepressor
OIOLDKHP_00699	7.96e-67	-	-	-	S	-	-	-	DNA binding
OIOLDKHP_00700	9.51e-15	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
OIOLDKHP_00701	4.95e-47	-	-	-	S	-	-	-	ERF superfamily
OIOLDKHP_00702	1.14e-77	-	-	-	S	-	-	-	Putative HNHc nuclease
OIOLDKHP_00703	1.57e-23	-	-	-	L	-	-	-	NUMOD4 motif
OIOLDKHP_00705	1.42e-28	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
OIOLDKHP_00706	5.22e-09	dnaC	-	-	L	ko:K02315	-	ko00000,ko03032	DNA replication protein
OIOLDKHP_00710	6.64e-41	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
OIOLDKHP_00719	2.13e-217	-	-	-	KL	-	-	-	DNA methylase
OIOLDKHP_00720	2.25e-54	-	-	-	S	-	-	-	endonuclease activity
OIOLDKHP_00721	6.25e-182	-	-	-	S	-	-	-	Terminase-like family
OIOLDKHP_00722	3.01e-159	-	-	-	S	-	-	-	Phage portal protein
OIOLDKHP_00723	1.35e-69	-	-	-	S	-	-	-	Phage Mu protein F like protein
OIOLDKHP_00726	6.47e-99	-	-	-	-	-	-	-	-
OIOLDKHP_00727	1.23e-34	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
OIOLDKHP_00729	1.9e-24	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
OIOLDKHP_00730	5.52e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF3168)
OIOLDKHP_00731	3.71e-79	-	-	-	S	-	-	-	Phage major tail protein 2
OIOLDKHP_00732	1.04e-32	-	-	-	S	-	-	-	Pfam:Phage_TAC_12
OIOLDKHP_00733	1.85e-36	-	-	-	-	-	-	-	-
OIOLDKHP_00734	9.77e-147	-	-	-	D	-	-	-	Phage tail tape measure protein
OIOLDKHP_00735	9.3e-110	-	-	-	S	-	-	-	phage tail
OIOLDKHP_00736	6.87e-275	-	-	-	M	-	-	-	Prophage endopeptidase tail
OIOLDKHP_00738	3.92e-45	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
OIOLDKHP_00741	1.88e-103	-	-	-	G	-	-	-	Peptidase_C39 like family
OIOLDKHP_00742	5.62e-272	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
OIOLDKHP_00743	4.68e-88	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
OIOLDKHP_00744	9.26e-205	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
OIOLDKHP_00745	3.74e-119	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
OIOLDKHP_00746	1.23e-85	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
OIOLDKHP_00747	7.22e-197	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
OIOLDKHP_00748	2.83e-65	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
OIOLDKHP_00749	7.43e-186	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
OIOLDKHP_00750	1.08e-57	cps3I	-	-	G	-	-	-	Acyltransferase family
OIOLDKHP_00751	4.55e-20	-	-	-	-	-	-	-	-
OIOLDKHP_00752	2.91e-150	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
OIOLDKHP_00753	7.7e-190	XK27_08315	-	-	M	-	-	-	Sulfatase
OIOLDKHP_00754	7.59e-88	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
OIOLDKHP_00755	6.73e-72	-	-	-	-	-	-	-	-
OIOLDKHP_00756	3.39e-109	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
OIOLDKHP_00757	5.79e-77	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
OIOLDKHP_00758	4.49e-94	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OIOLDKHP_00759	1.7e-222	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
OIOLDKHP_00760	1.72e-160	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
OIOLDKHP_00761	7.25e-214	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
OIOLDKHP_00762	4.64e-113	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
OIOLDKHP_00763	3.63e-127	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
OIOLDKHP_00764	1.5e-87	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OIOLDKHP_00765	5.34e-135	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
OIOLDKHP_00766	4.75e-215	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
OIOLDKHP_00767	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
OIOLDKHP_00768	5.11e-263	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
OIOLDKHP_00769	7.63e-237	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
OIOLDKHP_00771	5.63e-110	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OIOLDKHP_00772	3.3e-52	-	-	-	-	-	-	-	-
OIOLDKHP_00773	1.12e-151	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
OIOLDKHP_00774	3.42e-59	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
OIOLDKHP_00775	6.24e-277	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
OIOLDKHP_00776	4.23e-79	-	-	-	S	-	-	-	Helix-turn-helix domain
OIOLDKHP_00777	1.62e-156	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
OIOLDKHP_00778	1.12e-15	-	-	-	M	-	-	-	Lysin motif
OIOLDKHP_00779	1.45e-111	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
OIOLDKHP_00780	4.22e-106	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
OIOLDKHP_00781	5.08e-197	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
OIOLDKHP_00782	2.42e-88	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OIOLDKHP_00783	4.18e-40	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
OIOLDKHP_00784	4.63e-199	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OIOLDKHP_00785	6.69e-115	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
OIOLDKHP_00787	3.08e-276	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OIOLDKHP_00788	1.94e-222	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
OIOLDKHP_00789	4.73e-40	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OIOLDKHP_00790	3.32e-191	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OIOLDKHP_00791	1.73e-78	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphatase family
OIOLDKHP_00792	2.24e-220	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
OIOLDKHP_00793	1.93e-287	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
OIOLDKHP_00794	2.02e-48	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
OIOLDKHP_00796	2.83e-26	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
OIOLDKHP_00797	1.62e-140	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	Domain of unknown function (DUF4162)
OIOLDKHP_00798	3.32e-105	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type Na efflux pump, permease component
OIOLDKHP_00799	2.08e-121	-	-	-	EG	-	-	-	EamA-like transporter family
OIOLDKHP_00800	6.14e-100	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
OIOLDKHP_00801	3.72e-236	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OIOLDKHP_00802	3.4e-53	-	-	-	S	-	-	-	ASCH
OIOLDKHP_00803	3.9e-91	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase, peptidase S26
OIOLDKHP_00804	1.19e-147	-	-	-	S	-	-	-	EDD domain protein, DegV family
OIOLDKHP_00805	2.07e-52	-	-	-	K	-	-	-	Transcriptional regulator
OIOLDKHP_00806	2.54e-251	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
OIOLDKHP_00807	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OIOLDKHP_00808	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OIOLDKHP_00809	1.38e-106	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
OIOLDKHP_00810	9.22e-53	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
OIOLDKHP_00812	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
OIOLDKHP_00813	1.7e-211	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
OIOLDKHP_00814	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
OIOLDKHP_00815	6.47e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
OIOLDKHP_00816	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
OIOLDKHP_00817	3.26e-255	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
OIOLDKHP_00818	5.49e-54	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
OIOLDKHP_00819	1.16e-201	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
OIOLDKHP_00820	1.79e-119	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OIOLDKHP_00822	4.91e-104	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
OIOLDKHP_00823	4.92e-165	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OIOLDKHP_00824	1.34e-220	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
OIOLDKHP_00825	1.24e-173	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
OIOLDKHP_00826	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
OIOLDKHP_00827	7.72e-257	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
OIOLDKHP_00828	2.75e-190	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
OIOLDKHP_00829	1.21e-174	-	-	-	EG	-	-	-	EamA-like transporter family
OIOLDKHP_00830	6.31e-93	-	-	-	L	-	-	-	DNA alkylation repair enzyme
OIOLDKHP_00831	1.76e-232	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
OIOLDKHP_00832	5.44e-130	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OIOLDKHP_00833	6.85e-98	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
OIOLDKHP_00834	2.05e-185	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
OIOLDKHP_00836	2.95e-07	-	-	-	D	-	-	-	nuclear chromosome segregation
OIOLDKHP_00841	5.02e-50	-	-	-	-	-	-	-	-
OIOLDKHP_00842	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
OIOLDKHP_00843	1.46e-34	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
OIOLDKHP_00844	8.9e-48	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
OIOLDKHP_00845	3.81e-218	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
OIOLDKHP_00846	3.6e-57	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
OIOLDKHP_00848	4.96e-111	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
OIOLDKHP_00849	4.06e-218	araT1	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
OIOLDKHP_00850	4.04e-148	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
OIOLDKHP_00851	1.09e-184	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
OIOLDKHP_00852	3.69e-172	-	-	-	K	-	-	-	Transcriptional regulator
OIOLDKHP_00853	3.01e-114	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OIOLDKHP_00854	6.09e-109	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
OIOLDKHP_00855	5.19e-238	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
OIOLDKHP_00856	1.09e-140	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
OIOLDKHP_00857	7.51e-257	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
OIOLDKHP_00858	2.49e-97	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OIOLDKHP_00859	1.69e-164	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
OIOLDKHP_00860	3.83e-56	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OIOLDKHP_00861	1.03e-71	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
OIOLDKHP_00862	2.53e-71	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
OIOLDKHP_00863	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIOLDKHP_00864	1.24e-96	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
OIOLDKHP_00865	8.39e-147	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
OIOLDKHP_00866	1.21e-54	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
OIOLDKHP_00867	4.12e-182	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
OIOLDKHP_00868	5.6e-17	-	-	-	-	-	-	-	-
OIOLDKHP_00869	2e-88	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
OIOLDKHP_00870	4.31e-127	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
OIOLDKHP_00871	5.39e-162	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OIOLDKHP_00872	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OIOLDKHP_00873	7.45e-220	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OIOLDKHP_00874	3.97e-56	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
OIOLDKHP_00875	1.95e-88	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
OIOLDKHP_00876	1.15e-109	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIOLDKHP_00879	1.85e-12	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
OIOLDKHP_00880	2.88e-48	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
OIOLDKHP_00881	1.62e-49	-	-	-	E	-	-	-	Zn peptidase
OIOLDKHP_00883	1.81e-36	-	-	-	S	-	-	-	Short C-terminal domain
OIOLDKHP_00884	1.13e-23	-	-	-	L	-	-	-	nuclease
OIOLDKHP_00885	1.28e-17	-	-	-	-	-	-	-	-
OIOLDKHP_00886	7.48e-21	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
OIOLDKHP_00888	8.88e-11	-	-	-	L	-	-	-	Pfam:Integrase_AP2
OIOLDKHP_00889	6.84e-116	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
OIOLDKHP_00891	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
OIOLDKHP_00892	1.27e-49	-	-	-	S	-	-	-	repeat protein
OIOLDKHP_00893	2.93e-129	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
OIOLDKHP_00894	2.05e-255	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
OIOLDKHP_00895	3.73e-164	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
OIOLDKHP_00896	1.17e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
OIOLDKHP_00897	6.67e-257	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
OIOLDKHP_00898	1.42e-264	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OIOLDKHP_00899	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OIOLDKHP_00900	1.96e-106	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
OIOLDKHP_00901	1.67e-123	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OIOLDKHP_00902	2.54e-170	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OIOLDKHP_00903	1.77e-33	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
OIOLDKHP_00904	4.58e-68	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
OIOLDKHP_00905	2.14e-99	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
OIOLDKHP_00907	1.27e-135	ydhF	-	-	S	-	-	-	Aldo keto reductase
OIOLDKHP_00908	1.83e-31	-	-	-	K	-	-	-	Transcriptional regulator
OIOLDKHP_00909	7.26e-171	-	-	-	C	-	-	-	Aldo keto reductase
OIOLDKHP_00910	7.52e-74	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OIOLDKHP_00911	1.36e-200	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OIOLDKHP_00912	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
OIOLDKHP_00913	1.45e-167	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
OIOLDKHP_00914	1.85e-136	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
OIOLDKHP_00915	2.69e-142	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OIOLDKHP_00916	5.44e-87	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
OIOLDKHP_00917	1.87e-75	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
OIOLDKHP_00918	5.93e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
OIOLDKHP_00919	2.08e-148	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
OIOLDKHP_00922	6.21e-126	-	-	-	M	-	-	-	Glycosyltransferase like family 2
OIOLDKHP_00923	6.04e-107	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
OIOLDKHP_00924	3.38e-116	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
OIOLDKHP_00925	4.35e-160	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OIOLDKHP_00926	1.41e-98	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OIOLDKHP_00927	1.26e-107	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OIOLDKHP_00928	8.09e-72	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
OIOLDKHP_00929	4.9e-300	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
OIOLDKHP_00930	1.05e-179	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
OIOLDKHP_00931	1.71e-46	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
OIOLDKHP_00932	2.21e-275	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
OIOLDKHP_00933	2.58e-119	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
OIOLDKHP_00934	2.94e-155	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
OIOLDKHP_00935	5.67e-173	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
OIOLDKHP_00936	3.76e-143	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
OIOLDKHP_00937	1.69e-132	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
OIOLDKHP_00938	8.94e-184	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
OIOLDKHP_00939	1.71e-90	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
OIOLDKHP_00940	3.64e-63	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
OIOLDKHP_00941	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
OIOLDKHP_00942	2.81e-74	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
OIOLDKHP_00943	6.94e-28	-	-	-	-	-	-	-	-
OIOLDKHP_00945	2.58e-156	-	-	-	K	-	-	-	LysR substrate binding domain
OIOLDKHP_00946	2.77e-242	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIOLDKHP_00947	1.23e-118	-	-	-	S	-	-	-	Acyltransferase family
OIOLDKHP_00948	3.96e-202	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
OIOLDKHP_00949	2.81e-291	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
OIOLDKHP_00950	6.95e-96	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OIOLDKHP_00951	1.71e-175	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
OIOLDKHP_00952	1.24e-282	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OIOLDKHP_00953	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OIOLDKHP_00954	4.77e-132	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OIOLDKHP_00955	9.14e-41	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OIOLDKHP_00956	6.07e-123	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
OIOLDKHP_00957	5.17e-167	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
OIOLDKHP_00958	3.35e-65	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OIOLDKHP_00959	2.14e-95	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
OIOLDKHP_00960	2.86e-24	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
OIOLDKHP_00961	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OIOLDKHP_00962	4.34e-126	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
OIOLDKHP_00963	1.23e-37	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
OIOLDKHP_00964	4.09e-124	-	-	-	-	-	-	-	-
OIOLDKHP_00965	2.51e-22	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
OIOLDKHP_00968	1.78e-19	-	-	-	S	-	-	-	head morphogenesis protein, SPP1 gp7 family
OIOLDKHP_00969	3.3e-236	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
OIOLDKHP_00970	3.77e-102	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
OIOLDKHP_00971	2.27e-86	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
OIOLDKHP_00972	5.79e-54	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
OIOLDKHP_00973	3.68e-144	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
OIOLDKHP_00974	5.48e-96	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
OIOLDKHP_00975	2.39e-258	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIOLDKHP_00976	2.19e-191	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
OIOLDKHP_00977	1.74e-80	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
OIOLDKHP_00978	4.37e-70	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
OIOLDKHP_00979	2.04e-114	nanK	-	-	GK	-	-	-	ROK family
OIOLDKHP_00980	4.39e-162	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
OIOLDKHP_00981	4.52e-118	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
OIOLDKHP_00982	2.33e-95	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
OIOLDKHP_00983	1.31e-45	yphA	-	-	GM	-	-	-	NAD dependent epimerase/dehydratase family
OIOLDKHP_00984	2.16e-271	potE	-	-	E	-	-	-	Amino Acid
OIOLDKHP_00985	1.16e-08	-	-	-	-	-	-	-	-
OIOLDKHP_00986	5.44e-43	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OIOLDKHP_00987	2.94e-289	fusA1	-	-	J	-	-	-	elongation factor G
OIOLDKHP_00989	0.000189	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
OIOLDKHP_00991	8.26e-127	-	-	-	L	-	-	-	PLD-like domain
OIOLDKHP_00992	1.63e-63	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
OIOLDKHP_00993	3.54e-42	-	-	-	L	ko:K07483	-	ko00000	Transposase
OIOLDKHP_00994	3.68e-124	-	-	-	K	-	-	-	Transcriptional regulator
OIOLDKHP_00995	1.92e-264	arsR	-	-	K	-	-	-	DNA-binding transcription factor activity
OIOLDKHP_00996	1.73e-93	-	-	-	H	-	-	-	ThiF family
OIOLDKHP_00997	2.15e-298	-	-	-	EGP	-	-	-	Major Facilitator
OIOLDKHP_00998	1.68e-133	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
OIOLDKHP_00999	8.64e-128	-	-	-	EGP	-	-	-	Major Facilitator
OIOLDKHP_01002	6.36e-14	-	-	-	S	-	-	-	Domain of unknown function (DUF4176)
OIOLDKHP_01004	6.65e-41	-	-	-	-	-	-	-	-
OIOLDKHP_01005	6.74e-33	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
OIOLDKHP_01006	3.7e-141	-	-	-	-	-	-	-	-
OIOLDKHP_01007	2.09e-131	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
OIOLDKHP_01008	6.87e-312	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
OIOLDKHP_01009	2.12e-227	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
OIOLDKHP_01010	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OIOLDKHP_01011	1.09e-80	mipB	2.2.1.2	-	H	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
OIOLDKHP_01012	2.21e-47	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
OIOLDKHP_01013	7.39e-173	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
OIOLDKHP_01014	1.93e-106	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
OIOLDKHP_01015	7.01e-57	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
OIOLDKHP_01016	7.16e-94	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
OIOLDKHP_01017	4.79e-141	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
OIOLDKHP_01018	2.11e-204	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
OIOLDKHP_01019	6.42e-125	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
OIOLDKHP_01020	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
OIOLDKHP_01022	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
OIOLDKHP_01023	2.44e-89	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
OIOLDKHP_01029	2.79e-17	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
OIOLDKHP_01030	2.18e-52	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
OIOLDKHP_01031	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
OIOLDKHP_01032	2.21e-47	-	-	-	-	-	-	-	-
OIOLDKHP_01034	1.31e-160	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
OIOLDKHP_01035	6.78e-16	licT	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
OIOLDKHP_01036	5.43e-102	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
OIOLDKHP_01037	5.52e-173	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
OIOLDKHP_01038	5.2e-45	-	-	-	S	-	-	-	Replication initiator protein A (RepA) N-terminus
OIOLDKHP_01039	3.24e-142	-	-	-	L	-	-	-	Initiator Replication protein
OIOLDKHP_01043	3.84e-26	-	-	-	L	-	-	-	PLD-like domain
OIOLDKHP_01044	3.51e-74	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
OIOLDKHP_01045	2.43e-64	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
OIOLDKHP_01046	2.4e-41	-	-	-	L	-	-	-	MULE transposase domain
OIOLDKHP_01048	5.57e-80	-	-	-	V	-	-	-	HNH endonuclease
OIOLDKHP_01049	2.3e-28	-	-	-	L	-	-	-	MULE transposase domain
OIOLDKHP_01050	5.94e-64	-	-	-	L	-	-	-	MULE transposase domain
OIOLDKHP_01051	4.85e-168	-	-	-	F	-	-	-	NUDIX domain
OIOLDKHP_01052	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OIOLDKHP_01053	8.1e-11	pncA	-	-	Q	-	-	-	Isochorismatase family
OIOLDKHP_01054	7.95e-263	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OIOLDKHP_01055	8.79e-307	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
OIOLDKHP_01056	7.88e-87	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
OIOLDKHP_01057	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
OIOLDKHP_01058	7.44e-15	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OIOLDKHP_01059	5.31e-72	lssY	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
OIOLDKHP_01060	2.53e-106	lysR5	-	-	K	-	-	-	LysR substrate binding domain
OIOLDKHP_01061	5.78e-104	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
OIOLDKHP_01062	1.47e-54	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
OIOLDKHP_01063	5.53e-253	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
OIOLDKHP_01066	8.28e-64	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
OIOLDKHP_01067	1.27e-62	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
OIOLDKHP_01073	2.4e-191	-	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
OIOLDKHP_01074	2.42e-200	-	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
OIOLDKHP_01075	2.94e-168	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
OIOLDKHP_01076	9.31e-122	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
OIOLDKHP_01077	3.61e-232	-	-	-	L	-	-	-	Probable transposase
OIOLDKHP_01078	2.28e-73	-	-	-	M	-	-	-	Cna protein B-type domain
OIOLDKHP_01079	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
OIOLDKHP_01080	2.44e-104	-	-	-	-	-	-	-	-
OIOLDKHP_01081	8.14e-62	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
OIOLDKHP_01082	8.52e-200	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
OIOLDKHP_01083	2.24e-15	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
OIOLDKHP_01084	1.41e-30	-	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
OIOLDKHP_01085	0.0	-	-	-	L	-	-	-	MobA MobL family protein
OIOLDKHP_01086	6.89e-37	-	-	-	-	-	-	-	-
OIOLDKHP_01087	2.96e-55	-	-	-	-	-	-	-	-
OIOLDKHP_01088	5.46e-161	-	-	-	S	-	-	-	protein conserved in bacteria
OIOLDKHP_01089	1.99e-35	-	-	-	-	-	-	-	-
OIOLDKHP_01090	1.68e-53	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
OIOLDKHP_01091	1.4e-68	-	-	-	S	-	-	-	Fic/DOC family
OIOLDKHP_01099	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
OIOLDKHP_01100	9.07e-86	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
OIOLDKHP_01101	1.18e-258	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
OIOLDKHP_01102	6.89e-82	-	-	-	C	-	-	-	FMN binding
OIOLDKHP_01103	2.03e-291	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OIOLDKHP_01105	4.97e-199	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
OIOLDKHP_01106	2e-77	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
OIOLDKHP_01107	5.3e-12	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
OIOLDKHP_01108	1.36e-103	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
OIOLDKHP_01109	5.93e-128	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
OIOLDKHP_01110	1.49e-165	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cobalamin-independent synthase, Catalytic domain
OIOLDKHP_01111	1.14e-92	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
OIOLDKHP_01112	1.2e-248	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
OIOLDKHP_01113	2.56e-203	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
OIOLDKHP_01114	1.6e-70	oxyR5	-	-	K	-	-	-	Transcriptional regulator
OIOLDKHP_01115	1.54e-243	-	-	-	C	-	-	-	FMN_bind
OIOLDKHP_01116	3.59e-149	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
OIOLDKHP_01117	1.69e-254	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
OIOLDKHP_01118	8.38e-178	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
OIOLDKHP_01119	1.92e-101	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
OIOLDKHP_01120	2.41e-168	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
OIOLDKHP_01121	5.03e-190	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
OIOLDKHP_01122	1.82e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
OIOLDKHP_01123	1.02e-26	-	-	-	S	-	-	-	Cupredoxin-like domain
OIOLDKHP_01124	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
OIOLDKHP_01125	3.17e-78	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
OIOLDKHP_01126	2.18e-72	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
OIOLDKHP_01127	6.95e-112	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OIOLDKHP_01128	1.07e-277	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
OIOLDKHP_01129	4.36e-254	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
OIOLDKHP_01130	3.98e-189	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIOLDKHP_01131	7.43e-217	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIOLDKHP_01132	6.06e-230	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
OIOLDKHP_01133	1.99e-196	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
OIOLDKHP_01134	5.22e-21	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
OIOLDKHP_01135	9.59e-265	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
OIOLDKHP_01136	1.53e-143	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
OIOLDKHP_01137	2.35e-51	-	-	-	K	-	-	-	LytTr DNA-binding domain
OIOLDKHP_01139	2.6e-191	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
OIOLDKHP_01140	4.63e-30	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
OIOLDKHP_01141	2.53e-60	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
OIOLDKHP_01142	5.58e-69	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OIOLDKHP_01143	1.49e-208	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
OIOLDKHP_01144	4.78e-86	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter
OIOLDKHP_01145	1.78e-130	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
OIOLDKHP_01146	1.22e-57	ytcD	-	-	K	-	-	-	HxlR-like helix-turn-helix
OIOLDKHP_01147	5.75e-155	ytbE	-	-	S	-	-	-	reductase
OIOLDKHP_01148	1.11e-93	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OIOLDKHP_01150	1.16e-122	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
OIOLDKHP_01151	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
OIOLDKHP_01153	2.78e-54	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
OIOLDKHP_01154	1.37e-61	hmpT	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
OIOLDKHP_01155	1.26e-84	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
OIOLDKHP_01156	3.07e-06	sdpI	-	-	S	-	-	-	Protein of unknown function (DUF1648)
OIOLDKHP_01157	7.86e-140	dat	2.6.1.21	-	EH	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	PFAM aminotransferase, class IV
OIOLDKHP_01158	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
OIOLDKHP_01159	3.54e-59	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
OIOLDKHP_01160	4.55e-68	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
OIOLDKHP_01161	1.02e-08	-	-	-	-	-	-	-	-
OIOLDKHP_01165	1.3e-93	-	-	-	S	ko:K06919	-	ko00000	DNA primase
OIOLDKHP_01166	2.68e-23	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
OIOLDKHP_01172	6.79e-44	-	-	-	K	-	-	-	COG3617 Prophage antirepressor
OIOLDKHP_01175	1.59e-30	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
OIOLDKHP_01176	6.24e-156	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
OIOLDKHP_01177	1.8e-69	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
OIOLDKHP_01178	2.21e-73	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
OIOLDKHP_01179	1.42e-42	-	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
OIOLDKHP_01180	1.71e-97	azlC	-	-	E	-	-	-	branched-chain amino acid
OIOLDKHP_01181	1.13e-75	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
OIOLDKHP_01182	3.49e-149	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
OIOLDKHP_01183	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
OIOLDKHP_01184	2.67e-45	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
OIOLDKHP_01185	2.17e-240	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
OIOLDKHP_01186	1.85e-96	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
OIOLDKHP_01187	2.31e-141	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
OIOLDKHP_01189	4.78e-263	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
OIOLDKHP_01190	2.02e-78	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
OIOLDKHP_01191	6.92e-143	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
OIOLDKHP_01192	2.16e-192	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
OIOLDKHP_01193	2.82e-88	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
OIOLDKHP_01194	4.88e-66	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
OIOLDKHP_01195	3.08e-135	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
OIOLDKHP_01196	1.41e-220	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
OIOLDKHP_01197	2.19e-257	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
OIOLDKHP_01198	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
OIOLDKHP_01199	1.01e-236	noxE	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
OIOLDKHP_01200	1.66e-51	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
OIOLDKHP_01201	3.9e-134	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
OIOLDKHP_01202	8.27e-128	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
OIOLDKHP_01203	4.77e-122	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
OIOLDKHP_01204	3.75e-49	-	-	-	K	-	-	-	Transcriptional regulator
OIOLDKHP_01205	6.4e-138	-	-	-	P	-	-	-	Integral membrane protein TerC family
OIOLDKHP_01206	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
OIOLDKHP_01207	1.63e-85	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OIOLDKHP_01208	2.44e-235	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
OIOLDKHP_01209	5.09e-56	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
OIOLDKHP_01210	1.09e-121	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
OIOLDKHP_01212	4.21e-53	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
OIOLDKHP_01213	2.83e-199	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
OIOLDKHP_01214	1.57e-123	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OIOLDKHP_01215	1.42e-197	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OIOLDKHP_01216	3.93e-180	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIOLDKHP_01217	1.75e-45	-	-	-	-	-	-	-	-
OIOLDKHP_01218	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
OIOLDKHP_01219	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
OIOLDKHP_01220	7.22e-83	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
OIOLDKHP_01222	7.04e-93	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
OIOLDKHP_01223	1.36e-78	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
OIOLDKHP_01224	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
OIOLDKHP_01225	1.29e-91	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
OIOLDKHP_01226	1.17e-161	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
OIOLDKHP_01227	7.29e-130	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
OIOLDKHP_01228	8.74e-104	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
OIOLDKHP_01229	4.97e-153	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
OIOLDKHP_01230	1.02e-138	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
OIOLDKHP_01231	3.11e-33	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
OIOLDKHP_01232	2.94e-242	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
OIOLDKHP_01233	3.13e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
OIOLDKHP_01234	4.28e-115	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
OIOLDKHP_01235	1.87e-69	-	-	-	I	-	-	-	Alpha/beta hydrolase family
OIOLDKHP_01236	5.51e-50	-	-	-	-	-	-	-	-
OIOLDKHP_01237	1.47e-131	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
OIOLDKHP_01238	1.6e-126	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
OIOLDKHP_01239	3.47e-138	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
OIOLDKHP_01240	9.84e-72	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
OIOLDKHP_01241	4.71e-128	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
OIOLDKHP_01242	1.88e-114	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
OIOLDKHP_01243	8.26e-36	adhR	-	-	K	-	-	-	transcriptional regulator
OIOLDKHP_01244	3.12e-87	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
OIOLDKHP_01246	7.81e-193	-	-	-	EGP	-	-	-	Major Facilitator
OIOLDKHP_01247	1.69e-80	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
OIOLDKHP_01248	6.16e-113	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
OIOLDKHP_01249	1.67e-45	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
OIOLDKHP_01250	2.84e-148	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
OIOLDKHP_01251	3.23e-77	-	-	-	S	-	-	-	Glycosyltransferase like family 2
OIOLDKHP_01252	5.46e-181	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OIOLDKHP_01253	2.26e-130	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
OIOLDKHP_01254	7.5e-238	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
OIOLDKHP_01255	5.97e-166	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
OIOLDKHP_01256	7.12e-147	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
OIOLDKHP_01258	6.57e-108	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
OIOLDKHP_01259	4.12e-173	-	-	-	L	-	-	-	AAA ATPase domain
OIOLDKHP_01260	3.9e-138	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD/REP helicase N-terminal domain
OIOLDKHP_01261	5.23e-114	-	-	-	M	-	-	-	Glycosyl transferase family 8
OIOLDKHP_01262	8.03e-50	-	-	-	M	-	-	-	group 2 family protein
OIOLDKHP_01263	7.59e-114	-	-	-	-	-	-	-	-
OIOLDKHP_01264	1.43e-30	-	-	-	M	-	-	-	family 8
OIOLDKHP_01266	5.72e-83	-	-	-	S	ko:K16710	-	ko00000	Polysaccharide pyruvyl transferase
OIOLDKHP_01267	7.76e-140	cps2J	-	-	S	-	-	-	Polysaccharide biosynthesis protein
OIOLDKHP_01269	1.35e-91	epsB	-	-	M	-	-	-	biosynthesis protein
OIOLDKHP_01270	5.47e-118	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
OIOLDKHP_01271	1.15e-139	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
OIOLDKHP_01272	1.11e-162	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
OIOLDKHP_01273	5.65e-114	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
OIOLDKHP_01274	1.82e-148	-	-	-	M	-	-	-	Core-2/I-Branching enzyme
OIOLDKHP_01275	2.85e-247	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
OIOLDKHP_01276	2.34e-234	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
OIOLDKHP_01277	1.31e-81	-	-	-	D	-	-	-	Peptidase family M23
OIOLDKHP_01279	9.89e-172	tetA	-	-	EGP	ko:K08151,ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko01504,ko02000	Major facilitator Superfamily
OIOLDKHP_01280	2.51e-43	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
OIOLDKHP_01281	1.26e-268	potE	-	-	E	-	-	-	Amino Acid
OIOLDKHP_01282	1.64e-239	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
OIOLDKHP_01283	3.91e-143	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
OIOLDKHP_01284	8.17e-51	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
OIOLDKHP_01285	7.86e-171	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
OIOLDKHP_01286	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
OIOLDKHP_01287	4.21e-47	-	-	-	-	-	-	-	-
OIOLDKHP_01289	7.79e-18	-	-	-	-	-	-	-	-
OIOLDKHP_01290	1.47e-113	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
OIOLDKHP_01291	6.56e-50	blpT	-	-	-	-	-	-	-
OIOLDKHP_01292	2.04e-25	ps105	-	-	-	-	-	-	-
OIOLDKHP_01295	2.04e-171	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
OIOLDKHP_01296	1.6e-24	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
OIOLDKHP_01297	1.19e-151	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OIOLDKHP_01298	1.22e-195	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
OIOLDKHP_01299	1.51e-25	-	-	-	-	-	-	-	-
OIOLDKHP_01303	7.15e-147	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
OIOLDKHP_01304	7.02e-27	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
OIOLDKHP_01306	9.8e-113	saeS	2.7.13.3	-	T	ko:K10681	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
OIOLDKHP_01307	5.02e-98	saeR	-	-	K	ko:K10682	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
OIOLDKHP_01308	5.89e-132	-	-	-	S	-	-	-	Signal peptide protein, YSIRK family
OIOLDKHP_01309	1.38e-93	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
OIOLDKHP_01310	4.18e-46	-	-	-	-	-	-	-	-
OIOLDKHP_01311	6.78e-218	repA	-	-	S	-	-	-	Replication initiator protein A
OIOLDKHP_01312	2.3e-68	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
OIOLDKHP_01313	1.34e-166	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
OIOLDKHP_01314	5.3e-59	-	-	-	V	-	-	-	type I restriction modification DNA specificity domain
OIOLDKHP_01315	6.33e-152	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
OIOLDKHP_01316	4.25e-58	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
OIOLDKHP_01318	3.21e-58	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
OIOLDKHP_01319	5.73e-17	XK27_08315	-	-	M	-	-	-	Sulfatase
OIOLDKHP_01320	4.77e-199	XK27_08315	-	-	M	-	-	-	Sulfatase
OIOLDKHP_01322	6.82e-212	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
OIOLDKHP_01323	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
OIOLDKHP_01324	1.68e-108	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
OIOLDKHP_01325	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
OIOLDKHP_01326	1.14e-81	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
OIOLDKHP_01327	5.94e-107	pncA	-	-	Q	-	-	-	isochorismatase
OIOLDKHP_01328	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
OIOLDKHP_01329	3.72e-131	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
OIOLDKHP_01330	6.68e-219	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIOLDKHP_01331	1.7e-55	hxlR	-	-	K	-	-	-	Transcriptional regulator, HxlR family
OIOLDKHP_01332	5.43e-209	-	-	-	C	-	-	-	Luciferase-like monooxygenase
OIOLDKHP_01333	7.62e-234	-	-	-	L	-	-	-	Probable transposase
OIOLDKHP_01334	1.75e-86	-	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
OIOLDKHP_01335	4.86e-148	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
OIOLDKHP_01336	2.62e-97	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
OIOLDKHP_01337	8.37e-76	-	-	-	EG	-	-	-	EamA-like transporter family
OIOLDKHP_01338	3.2e-148	ydbI	-	-	K	-	-	-	AI-2E family transporter
OIOLDKHP_01339	6.34e-217	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
OIOLDKHP_01340	3.53e-158	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OIOLDKHP_01341	0.000331	-	-	-	S	-	-	-	zinc-ribbon domain
OIOLDKHP_01343	7.9e-135	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
OIOLDKHP_01344	6.22e-164	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
OIOLDKHP_01345	7.19e-19	-	-	-	-	-	-	-	-
OIOLDKHP_01346	8.82e-133	-	-	-	E	-	-	-	AzlC protein
OIOLDKHP_01347	2.61e-52	-	-	-	S	-	-	-	branched-chain amino acid
OIOLDKHP_01348	2.24e-80	-	-	-	I	-	-	-	alpha/beta hydrolase fold
OIOLDKHP_01349	1.7e-23	-	-	-	-	-	-	-	-
OIOLDKHP_01350	9.17e-75	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
OIOLDKHP_01351	2.39e-27	-	-	-	-	-	-	-	-
OIOLDKHP_01352	1.17e-116	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
OIOLDKHP_01353	3.57e-115	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
OIOLDKHP_01354	1.37e-37	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
OIOLDKHP_01355	9.59e-104	-	-	-	S	-	-	-	Putative threonine/serine exporter
OIOLDKHP_01356	4.85e-65	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
OIOLDKHP_01357	6.16e-157	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
OIOLDKHP_01358	1.2e-109	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
OIOLDKHP_01359	3.2e-45	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
OIOLDKHP_01360	1.09e-28	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OIOLDKHP_01361	1.18e-28	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OIOLDKHP_01362	6.6e-84	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
OIOLDKHP_01364	3.64e-67	ccl	-	-	S	-	-	-	QueT transporter
OIOLDKHP_01365	7.29e-46	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
OIOLDKHP_01366	4.48e-131	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
OIOLDKHP_01367	1.24e-137	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
OIOLDKHP_01368	3.68e-219	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OIOLDKHP_01369	1.84e-122	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OIOLDKHP_01370	6.38e-110	-	-	-	S	-	-	-	Alpha beta hydrolase
OIOLDKHP_01371	2.42e-57	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OIOLDKHP_01372	1.39e-174	-	-	-	V	-	-	-	MatE
OIOLDKHP_01373	6.88e-200	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
OIOLDKHP_01374	1.99e-92	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIOLDKHP_01375	2.28e-125	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
OIOLDKHP_01376	3.21e-162	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
OIOLDKHP_01377	3.21e-93	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
OIOLDKHP_01378	2.76e-33	-	-	-	-	-	-	-	-
OIOLDKHP_01379	6.84e-232	yhdP	-	-	S	-	-	-	Transporter associated domain
OIOLDKHP_01380	1.01e-100	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
OIOLDKHP_01381	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
OIOLDKHP_01382	5.89e-316	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
OIOLDKHP_01383	6.14e-269	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
OIOLDKHP_01384	1e-68	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
OIOLDKHP_01385	2.03e-16	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
OIOLDKHP_01386	2.23e-123	-	-	-	-	-	-	-	-
OIOLDKHP_01387	3.89e-17	-	-	-	-	-	-	-	-
OIOLDKHP_01388	2.45e-132	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
OIOLDKHP_01389	4.84e-126	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
OIOLDKHP_01390	4.89e-111	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
OIOLDKHP_01391	1.88e-104	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
OIOLDKHP_01392	5.79e-240	steT	-	-	E	ko:K03294	-	ko00000	amino acid
OIOLDKHP_01393	2.79e-14	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
OIOLDKHP_01394	8.32e-188	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
OIOLDKHP_01395	1.63e-68	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
OIOLDKHP_01396	4.32e-100	-	-	-	K	-	-	-	rpiR family
OIOLDKHP_01397	8.14e-223	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OIOLDKHP_01398	3.24e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
OIOLDKHP_01399	1.34e-138	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OIOLDKHP_01400	6.55e-130	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
OIOLDKHP_01401	1.34e-52	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
OIOLDKHP_01402	4.58e-183	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OIOLDKHP_01403	5.93e-60	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OIOLDKHP_01404	9.15e-72	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OIOLDKHP_01405	1.62e-149	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OIOLDKHP_01406	8.95e-95	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OIOLDKHP_01407	2.63e-32	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
OIOLDKHP_01408	5.05e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OIOLDKHP_01409	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OIOLDKHP_01410	3.84e-62	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OIOLDKHP_01411	1.61e-119	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OIOLDKHP_01412	4.1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OIOLDKHP_01413	5.17e-86	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OIOLDKHP_01414	4.99e-113	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OIOLDKHP_01415	2.4e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OIOLDKHP_01416	2.08e-106	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OIOLDKHP_01417	1.65e-31	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
OIOLDKHP_01418	1.13e-88	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
OIOLDKHP_01419	1.05e-266	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
OIOLDKHP_01420	8.94e-143	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
OIOLDKHP_01421	7.16e-47	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OIOLDKHP_01422	1.72e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
OIOLDKHP_01423	7.34e-74	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OIOLDKHP_01424	1.24e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OIOLDKHP_01425	1.93e-198	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OIOLDKHP_01426	4.47e-71	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
OIOLDKHP_01427	2.27e-127	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OIOLDKHP_01428	8.76e-140	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OIOLDKHP_01429	3.1e-138	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OIOLDKHP_01430	6.22e-160	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
OIOLDKHP_01431	1.04e-99	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OIOLDKHP_01432	2.29e-79	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
OIOLDKHP_01434	2.82e-307	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
OIOLDKHP_01435	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
OIOLDKHP_01436	1.01e-79	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
OIOLDKHP_01437	8.99e-111	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
OIOLDKHP_01438	1.24e-137	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
OIOLDKHP_01439	2.1e-41	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
OIOLDKHP_01440	1.84e-110	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
OIOLDKHP_01441	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
OIOLDKHP_01442	2.6e-62	-	-	-	M	-	-	-	LysM domain protein
OIOLDKHP_01444	4.11e-142	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
OIOLDKHP_01445	2.64e-128	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
OIOLDKHP_01446	8.18e-73	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
OIOLDKHP_01447	1.43e-68	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
OIOLDKHP_01448	1.17e-260	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OIOLDKHP_01449	5.16e-179	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OIOLDKHP_01450	2.2e-110	-	-	-	S	-	-	-	(CBS) domain
OIOLDKHP_01451	4.72e-201	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
OIOLDKHP_01452	1.45e-95	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
OIOLDKHP_01453	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OIOLDKHP_01454	3.29e-173	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
OIOLDKHP_01455	1.1e-42	yabO	-	-	J	-	-	-	S4 domain protein
OIOLDKHP_01456	2.11e-28	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
OIOLDKHP_01457	1.23e-62	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
OIOLDKHP_01458	1.62e-118	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
OIOLDKHP_01459	2.49e-100	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
OIOLDKHP_01460	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIOLDKHP_01461	6.53e-167	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OIOLDKHP_01462	2.4e-214	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OIOLDKHP_01463	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
OIOLDKHP_01471	2.92e-189	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
OIOLDKHP_01472	7.81e-147	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
OIOLDKHP_01473	2.2e-187	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
OIOLDKHP_01474	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
OIOLDKHP_01475	6.09e-96	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
OIOLDKHP_01476	3.42e-31	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
OIOLDKHP_01477	9.49e-22	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily
OIOLDKHP_01478	7.87e-111	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OIOLDKHP_01479	1.41e-32	-	-	-	-	-	-	-	-
OIOLDKHP_01480	1.47e-30	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
OIOLDKHP_01481	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OIOLDKHP_01482	1.93e-315	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OIOLDKHP_01483	2.12e-250	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OIOLDKHP_01484	6.79e-246	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
OIOLDKHP_01485	9.71e-274	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OIOLDKHP_01486	0.000483	-	-	-	S	-	-	-	Tetratricopeptide repeat
OIOLDKHP_01487	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OIOLDKHP_01488	2.18e-146	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIOLDKHP_01489	1.06e-52	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OIOLDKHP_01490	1.33e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
OIOLDKHP_01491	2.49e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
OIOLDKHP_01492	2.91e-249	-	-	-	E	ko:K03294	-	ko00000	amino acid
OIOLDKHP_01493	4.4e-78	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
OIOLDKHP_01494	2.25e-144	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
OIOLDKHP_01495	3.22e-74	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OIOLDKHP_01496	1.99e-37	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
OIOLDKHP_01497	1.32e-55	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
OIOLDKHP_01498	9.04e-263	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OIOLDKHP_01499	1.51e-53	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OIOLDKHP_01500	1.12e-187	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
OIOLDKHP_01501	1.04e-290	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
OIOLDKHP_01502	1.2e-128	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
OIOLDKHP_01503	9.72e-35	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIOLDKHP_01504	1.08e-180	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
OIOLDKHP_01505	1.56e-305	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OIOLDKHP_01506	4.92e-302	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
OIOLDKHP_01507	7.35e-69	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
OIOLDKHP_01508	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
OIOLDKHP_01509	6.12e-73	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
OIOLDKHP_01510	1.38e-145	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
OIOLDKHP_01511	3.99e-238	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
OIOLDKHP_01512	3.18e-115	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
OIOLDKHP_01513	2.9e-191	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OIOLDKHP_01514	1.55e-177	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OIOLDKHP_01515	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OIOLDKHP_01516	1.87e-153	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OIOLDKHP_01517	8.22e-30	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
OIOLDKHP_01518	8.34e-132	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
OIOLDKHP_01519	5.39e-120	-	-	-	M	-	-	-	Phosphotransferase enzyme family
OIOLDKHP_01520	7.81e-35	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
OIOLDKHP_01521	2.21e-236	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
OIOLDKHP_01522	2.21e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
OIOLDKHP_01523	3.25e-36	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
OIOLDKHP_01524	2.82e-214	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
OIOLDKHP_01525	2.53e-261	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OIOLDKHP_01526	8.32e-21	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
OIOLDKHP_01527	3.59e-69	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
OIOLDKHP_01528	8.04e-313	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OIOLDKHP_01529	9.43e-181	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OIOLDKHP_01530	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OIOLDKHP_01531	8.06e-74	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OIOLDKHP_01532	2.96e-57	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OIOLDKHP_01533	1.39e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OIOLDKHP_01534	2.33e-124	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
OIOLDKHP_01535	2.18e-129	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OIOLDKHP_01536	1.9e-171	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
OIOLDKHP_01537	7.51e-114	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
OIOLDKHP_01538	1.04e-230	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OIOLDKHP_01539	1.19e-111	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
OIOLDKHP_01540	1.79e-278	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
OIOLDKHP_01541	9.35e-141	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
OIOLDKHP_01542	1.67e-137	ampC	-	-	V	-	-	-	Beta-lactamase
OIOLDKHP_01543	1.83e-41	-	-	-	-	-	-	-	-
OIOLDKHP_01544	7.44e-153	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
OIOLDKHP_01545	8.61e-258	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
OIOLDKHP_01547	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
OIOLDKHP_01548	5.74e-218	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
OIOLDKHP_01549	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
OIOLDKHP_01550	3.65e-75	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OIOLDKHP_01551	1.51e-165	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
OIOLDKHP_01552	7.4e-120	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
OIOLDKHP_01553	1.92e-150	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OIOLDKHP_01554	6.33e-74	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OIOLDKHP_01555	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OIOLDKHP_01556	2.85e-35	ylxQ	-	-	J	-	-	-	ribosomal protein
OIOLDKHP_01557	3.32e-53	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
OIOLDKHP_01558	1.25e-216	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
OIOLDKHP_01559	4.7e-85	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
OIOLDKHP_01560	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OIOLDKHP_01561	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
OIOLDKHP_01562	2.52e-196	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
OIOLDKHP_01563	1.58e-131	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
OIOLDKHP_01564	2.86e-134	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OIOLDKHP_01565	8.26e-105	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
OIOLDKHP_01566	1.02e-147	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
OIOLDKHP_01567	8.28e-64	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
OIOLDKHP_01568	6.13e-47	-	2.1.1.63	-	H	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIOLDKHP_01570	3.28e-312	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
OIOLDKHP_01571	1.3e-59	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
OIOLDKHP_01572	1.56e-257	ynbB	-	-	P	-	-	-	aluminum resistance
OIOLDKHP_01573	6.09e-141	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OIOLDKHP_01574	6.17e-24	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
OIOLDKHP_01575	1.19e-59	yqhL	-	-	P	-	-	-	Rhodanese-like protein
OIOLDKHP_01576	8.22e-203	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
OIOLDKHP_01577	2.47e-34	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
OIOLDKHP_01578	2.24e-90	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
OIOLDKHP_01579	2.55e-49	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OIOLDKHP_01580	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
OIOLDKHP_01582	1.14e-85	yciQ	-	-	P	-	-	-	membrane protein (DUF2207)
OIOLDKHP_01583	2.16e-58	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
OIOLDKHP_01584	2.28e-118	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
OIOLDKHP_01585	3.98e-36	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
OIOLDKHP_01586	7.41e-41	ynzC	-	-	S	-	-	-	UPF0291 protein
OIOLDKHP_01587	1.29e-106	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OIOLDKHP_01588	3.33e-235	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
OIOLDKHP_01589	5.91e-65	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
OIOLDKHP_01590	6.31e-154	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
OIOLDKHP_01591	8.84e-104	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
OIOLDKHP_01592	1.44e-23	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OIOLDKHP_01593	7.01e-183	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OIOLDKHP_01594	3.85e-132	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OIOLDKHP_01595	7.18e-47	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OIOLDKHP_01596	1.4e-60	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
OIOLDKHP_01597	3.77e-123	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OIOLDKHP_01598	1.45e-48	-	-	-	S	-	-	-	Protein conserved in bacteria
OIOLDKHP_01599	1.61e-147	-	-	-	-	-	-	-	-
OIOLDKHP_01600	4.27e-143	-	-	-	-	-	-	-	-
OIOLDKHP_01601	3.4e-119	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
OIOLDKHP_01602	2.24e-16	-	3.5.1.28	CBM50	M	ko:K22409	-	ko00000,ko01000	Lysin motif
OIOLDKHP_01603	5.63e-195	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
OIOLDKHP_01604	3.03e-183	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
OIOLDKHP_01605	2.04e-69	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
OIOLDKHP_01606	5.64e-69	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
OIOLDKHP_01607	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
OIOLDKHP_01608	9.8e-152	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
OIOLDKHP_01609	1.31e-154	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
OIOLDKHP_01610	4.88e-90	-	-	-	K	-	-	-	Sugar-specific transcriptional regulator TrmB
OIOLDKHP_01611	6.71e-214	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
OIOLDKHP_01612	4.06e-228	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
OIOLDKHP_01613	0.0	-	-	-	E	-	-	-	Amino acid permease
OIOLDKHP_01614	9.38e-110	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
OIOLDKHP_01615	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
OIOLDKHP_01616	1.35e-95	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
OIOLDKHP_01617	3.51e-270	-	-	-	G	ko:K16211	-	ko00000,ko02000	Transporter, major facilitator family protein
OIOLDKHP_01618	1.64e-126	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
OIOLDKHP_01619	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
OIOLDKHP_01622	1.39e-201	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
OIOLDKHP_01623	3.09e-160	mocA	-	-	S	-	-	-	Oxidoreductase
OIOLDKHP_01624	7.99e-33	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
OIOLDKHP_01625	4.58e-213	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
OIOLDKHP_01626	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
OIOLDKHP_01627	6.37e-244	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
OIOLDKHP_01628	7.84e-157	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
OIOLDKHP_01629	8.3e-210	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OIOLDKHP_01630	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OIOLDKHP_01631	3.8e-275	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
OIOLDKHP_01632	5.43e-46	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
OIOLDKHP_01633	1.46e-277	gdhA	1.4.1.3, 1.4.1.4	-	E	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	ko00000,ko00001,ko00002,ko01000,ko04147	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
OIOLDKHP_01634	2.28e-262	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
OIOLDKHP_01635	1.32e-41	-	-	-	K	-	-	-	GNAT family
OIOLDKHP_01636	1.96e-54	-	-	-	-	-	-	-	-
OIOLDKHP_01638	1.27e-228	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
OIOLDKHP_01639	1.3e-118	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
OIOLDKHP_01640	1.79e-148	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OIOLDKHP_01641	5.56e-124	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
OIOLDKHP_01642	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
OIOLDKHP_01643	1.21e-45	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
OIOLDKHP_01644	1.56e-254	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
OIOLDKHP_01645	1.37e-96	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
OIOLDKHP_01646	7.37e-77	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
OIOLDKHP_01647	2.31e-81	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
OIOLDKHP_01648	2.15e-162	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
OIOLDKHP_01649	1.69e-313	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
OIOLDKHP_01650	7.97e-90	mleR	-	-	K	-	-	-	LysR family
OIOLDKHP_01651	1.81e-74	napB	-	-	K	-	-	-	transcriptional
OIOLDKHP_01652	1.17e-52	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
OIOLDKHP_01653	2.3e-78	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
OIOLDKHP_01654	2.15e-59	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
OIOLDKHP_01655	4.3e-284	-	-	-	M	-	-	-	Rib/alpha-like repeat
OIOLDKHP_01657	1.14e-129	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
OIOLDKHP_01658	1.28e-76	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
OIOLDKHP_01659	5.38e-204	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OIOLDKHP_01660	3.66e-50	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
OIOLDKHP_01661	3.63e-267	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
OIOLDKHP_01662	1.38e-249	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
OIOLDKHP_01663	1.77e-300	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
OIOLDKHP_01664	4.82e-20	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
OIOLDKHP_01665	1e-221	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
OIOLDKHP_01666	3.47e-75	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
OIOLDKHP_01667	2.11e-122	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OIOLDKHP_01668	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
OIOLDKHP_01669	3.59e-92	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
OIOLDKHP_01670	1.1e-84	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
OIOLDKHP_01673	4.88e-205	spoVK	-	-	O	ko:K06413	-	ko00000	PFAM ATPase family associated with various cellular activities (AAA)
OIOLDKHP_01674	4.9e-288	-	-	-	S	-	-	-	Protein of unknown function DUF262
OIOLDKHP_01675	7.27e-92	-	-	-	S	-	-	-	Domain of unknown function (DUF3841)
OIOLDKHP_01676	6.05e-75	-	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
OIOLDKHP_01677	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
OIOLDKHP_01678	2.13e-265	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OIOLDKHP_01679	8.82e-184	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
OIOLDKHP_01680	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIOLDKHP_01681	4.18e-294	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
OIOLDKHP_01682	1.34e-50	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIOLDKHP_01683	1.39e-204	camS	-	-	S	-	-	-	sex pheromone
OIOLDKHP_01684	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OIOLDKHP_01685	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
OIOLDKHP_01686	1.64e-182	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OIOLDKHP_01694	1.46e-157	yvgN	-	-	C	-	-	-	Aldo keto reductase
OIOLDKHP_01695	3.98e-155	yvgN	-	-	C	-	-	-	Aldo keto reductase
OIOLDKHP_01696	8.22e-90	rdrB	-	-	K	ko:K02444,ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
OIOLDKHP_01697	1.28e-60	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
OIOLDKHP_01698	9.32e-55	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
OIOLDKHP_01699	3.52e-287	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
OIOLDKHP_01701	2.32e-132	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
OIOLDKHP_01703	9.99e-40	-	-	-	S	-	-	-	COG NOG19168 non supervised orthologous group
OIOLDKHP_01704	2.89e-240	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
OIOLDKHP_01706	3.92e-135	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
OIOLDKHP_01708	1.06e-64	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
OIOLDKHP_01710	4.71e-68	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
OIOLDKHP_01711	1.18e-128	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	Adenine specific DNA methylase Mod
OIOLDKHP_01712	2.78e-69	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
OIOLDKHP_01713	9.74e-68	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	Adenine specific DNA methylase Mod
OIOLDKHP_01714	1.83e-140	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	Adenine specific DNA methylase Mod
OIOLDKHP_01715	1.35e-66	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
OIOLDKHP_01716	2.47e-140	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	Adenine specific DNA methylase Mod
OIOLDKHP_01717	0.0	sthIR	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
OIOLDKHP_01719	1.25e-14	-	-	-	-	-	-	-	-
OIOLDKHP_01720	6.17e-62	-	-	-	L	ko:K07451,ko:K07453	-	ko00000,ko01000,ko02048	HNH endonuclease
OIOLDKHP_01723	8.31e-152	potE2	-	-	E	ko:K03294	-	ko00000	amino acid
OIOLDKHP_01724	3.98e-41	potE2	-	-	E	ko:K03294	-	ko00000	amino acid
OIOLDKHP_01725	2.15e-90	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
OIOLDKHP_01726	2.43e-85	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
OIOLDKHP_01727	1.92e-148	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OIOLDKHP_01728	2.29e-75	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
OIOLDKHP_01729	3.26e-102	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
OIOLDKHP_01730	4.15e-61	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
OIOLDKHP_01733	1.73e-49	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
OIOLDKHP_01734	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
OIOLDKHP_01735	1.22e-66	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
OIOLDKHP_01736	2.01e-76	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
OIOLDKHP_01737	2.85e-197	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
OIOLDKHP_01738	8.45e-120	-	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
OIOLDKHP_01739	1.43e-160	-	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
OIOLDKHP_01740	1.54e-55	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
OIOLDKHP_01741	2.64e-26	tnp	-	-	-	ko:K07498	-	ko00000	-
OIOLDKHP_01742	1.32e-33	-	-	-	L	ko:K07498	-	ko00000	Transposase
OIOLDKHP_01743	3.43e-45	-	-	-	P	-	-	-	Heavy-metal-associated domain
OIOLDKHP_01744	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
OIOLDKHP_01745	1.2e-28	-	-	-	L	ko:K07483	-	ko00000	PFAM transposase IS3 IS911 family protein
OIOLDKHP_01746	1.31e-46	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
OIOLDKHP_01747	3.04e-44	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
OIOLDKHP_01748	3.08e-167	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
OIOLDKHP_01749	1.14e-121	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
OIOLDKHP_01750	6.52e-90	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
OIOLDKHP_01751	3.01e-176	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
OIOLDKHP_01752	1.73e-148	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
OIOLDKHP_01753	4.85e-270	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	FAD binding domain
OIOLDKHP_01754	2.97e-175	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OIOLDKHP_01755	2.98e-90	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
OIOLDKHP_01756	5.14e-180	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase family
OIOLDKHP_01760	4.9e-24	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
OIOLDKHP_01761	1.44e-101	bsh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
OIOLDKHP_01762	5.45e-14	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
OIOLDKHP_01763	2.12e-48	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
OIOLDKHP_01764	2.37e-97	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
OIOLDKHP_01765	1.09e-73	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
OIOLDKHP_01766	5.51e-67	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
OIOLDKHP_01767	6.88e-100	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
OIOLDKHP_01768	1.15e-126	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
OIOLDKHP_01769	8.24e-99	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
OIOLDKHP_01770	1.42e-34	-	-	-	-	-	-	-	-
OIOLDKHP_01771	5.32e-18	-	-	-	-	-	-	-	-
OIOLDKHP_01772	1.07e-141	rssA	-	-	S	-	-	-	Phospholipase, patatin family
OIOLDKHP_01773	5.49e-175	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OIOLDKHP_01774	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
OIOLDKHP_01775	1.25e-63	-	-	-	S	-	-	-	VIT family
OIOLDKHP_01776	9.19e-304	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
OIOLDKHP_01777	1.15e-53	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
OIOLDKHP_01778	1.39e-182	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OIOLDKHP_01779	1.3e-180	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
OIOLDKHP_01780	7.42e-148	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
OIOLDKHP_01781	6.35e-281	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
OIOLDKHP_01782	9.03e-317	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
OIOLDKHP_01783	1.1e-172	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
OIOLDKHP_01784	5.16e-146	ddh	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OIOLDKHP_01785	1.72e-39	-	-	-	S	-	-	-	Belongs to the HesB IscA family
OIOLDKHP_01786	1.38e-83	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
OIOLDKHP_01788	5e-67	-	-	-	K	-	-	-	LysR substrate binding domain
OIOLDKHP_01789	1.66e-152	-	-	-	S	-	-	-	Conserved hypothetical protein 698
OIOLDKHP_01790	2.06e-253	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
OIOLDKHP_01791	3.78e-138	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OIOLDKHP_01792	8.2e-65	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
OIOLDKHP_01793	2.29e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
OIOLDKHP_01794	1.1e-257	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OIOLDKHP_01795	8.98e-202	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
OIOLDKHP_01796	4.51e-27	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
OIOLDKHP_01797	1.38e-192	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OIOLDKHP_01798	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OIOLDKHP_01799	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OIOLDKHP_01800	7.37e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
OIOLDKHP_01801	6.48e-89	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
OIOLDKHP_01802	3.82e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OIOLDKHP_01803	4.29e-140	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
OIOLDKHP_01804	9.4e-148	-	-	-	S	-	-	-	Glycosyl transferase family 2
OIOLDKHP_01805	2.26e-81	-	-	-	D	-	-	-	peptidase
OIOLDKHP_01806	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
OIOLDKHP_01807	3.01e-60	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
OIOLDKHP_01808	6.14e-52	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
OIOLDKHP_01809	2.65e-306	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
OIOLDKHP_01810	5.01e-22	yneR	-	-	-	-	-	-	-
OIOLDKHP_01811	3.57e-290	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OIOLDKHP_01812	2.16e-283	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
OIOLDKHP_01813	2.34e-136	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
OIOLDKHP_01814	1.29e-192	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
OIOLDKHP_01815	4.15e-12	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
OIOLDKHP_01816	1.27e-140	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
OIOLDKHP_01817	1.86e-212	-	-	-	S	-	-	-	Putative threonine/serine exporter
OIOLDKHP_01818	6.27e-90	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
OIOLDKHP_01819	9.44e-121	yicL	-	-	EG	-	-	-	EamA-like transporter family
OIOLDKHP_01820	2.25e-278	pepF	-	-	E	-	-	-	Oligopeptidase F
OIOLDKHP_01821	2.04e-137	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
OIOLDKHP_01822	2.85e-224	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
OIOLDKHP_01823	4.63e-175	-	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
OIOLDKHP_01824	3.41e-79	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
OIOLDKHP_01825	2.51e-31	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
OIOLDKHP_01827	1.06e-216	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
OIOLDKHP_01828	4.68e-41	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
OIOLDKHP_01829	4.36e-269	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
OIOLDKHP_01830	1.11e-286	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
OIOLDKHP_01832	4.44e-107	-	-	-	S	ko:K19175	-	ko00000,ko02048	Domain of unknown function DUF87
OIOLDKHP_01834	4.07e-135	yxeH	-	-	S	-	-	-	hydrolase
OIOLDKHP_01835	2.43e-151	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
OIOLDKHP_01836	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
OIOLDKHP_01837	7.57e-126	yycH	-	-	S	-	-	-	YycH protein
OIOLDKHP_01838	4.75e-100	yycI	-	-	S	-	-	-	YycH protein
OIOLDKHP_01839	4.78e-41	-	-	-	S	-	-	-	YjbR
OIOLDKHP_01840	1.85e-147	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
OIOLDKHP_01841	2.33e-187	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
OIOLDKHP_01842	7.88e-94	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OIOLDKHP_01843	2.65e-52	-	-	-	GM	-	-	-	NAD(P)H-binding
OIOLDKHP_01844	3.67e-34	-	-	-	K	-	-	-	MarR family transcriptional regulator
OIOLDKHP_01845	5.45e-112	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
OIOLDKHP_01846	7.15e-58	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
OIOLDKHP_01847	5.32e-260	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	glycerol-3-phosphate transporter
OIOLDKHP_01848	1.72e-38	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
OIOLDKHP_01849	3.75e-23	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
OIOLDKHP_01850	5.93e-49	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
OIOLDKHP_01851	4.34e-93	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
OIOLDKHP_01852	1.27e-272	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
OIOLDKHP_01853	1.62e-186	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
OIOLDKHP_01854	3.57e-186	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
OIOLDKHP_01855	2.07e-106	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OIOLDKHP_01856	3.54e-140	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
OIOLDKHP_01857	2.65e-252	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
OIOLDKHP_01858	2.65e-35	-	-	-	-	-	-	-	-
OIOLDKHP_01859	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
OIOLDKHP_01860	1.01e-77	-	-	-	T	-	-	-	Universal stress protein family
OIOLDKHP_01862	5.42e-272	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
OIOLDKHP_01863	2.87e-213	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
OIOLDKHP_01882	5.21e-226	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OIOLDKHP_01883	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
OIOLDKHP_01884	6.58e-245	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
OIOLDKHP_01885	5.68e-243	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
OIOLDKHP_01886	2.41e-78	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
OIOLDKHP_01887	5.46e-105	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OIOLDKHP_01888	4.38e-242	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
OIOLDKHP_01889	3.01e-78	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
OIOLDKHP_01890	2.41e-91	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
OIOLDKHP_01891	0.0	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
OIOLDKHP_01893	1.26e-48	-	-	-	-	-	-	-	-
OIOLDKHP_01894	9.26e-87	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
OIOLDKHP_01895	1.29e-79	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
OIOLDKHP_01896	4.92e-128	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OIOLDKHP_01897	1.48e-36	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIOLDKHP_01898	2.98e-131	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
OIOLDKHP_01899	3.82e-126	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
OIOLDKHP_01900	5.79e-247	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OIOLDKHP_01901	2.34e-60	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
OIOLDKHP_01902	5.39e-83	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
OIOLDKHP_01903	2.06e-274	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
OIOLDKHP_01904	3.3e-160	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OIOLDKHP_01905	4.27e-130	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
OIOLDKHP_01906	7.35e-140	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
OIOLDKHP_01907	1.27e-289	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OIOLDKHP_01908	2.1e-305	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
OIOLDKHP_01909	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
OIOLDKHP_01910	1.05e-152	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
OIOLDKHP_01911	3.09e-59	ykuL	-	-	S	-	-	-	CBS domain
OIOLDKHP_01912	1.39e-91	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
OIOLDKHP_01913	4.06e-224	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
OIOLDKHP_01914	9.23e-115	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
OIOLDKHP_01916	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
OIOLDKHP_01917	2.92e-28	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
OIOLDKHP_01918	6.56e-163	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
OIOLDKHP_01919	1.22e-144	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
OIOLDKHP_01921	3.15e-69	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
OIOLDKHP_01922	1.76e-121	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
OIOLDKHP_01923	8.95e-85	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
OIOLDKHP_01924	3.39e-125	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
OIOLDKHP_01925	8.2e-131	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
OIOLDKHP_01926	2.95e-59	ytpP	-	-	CO	-	-	-	Thioredoxin
OIOLDKHP_01927	2.48e-97	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OIOLDKHP_01928	5.61e-297	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
OIOLDKHP_01929	1.24e-282	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
OIOLDKHP_01930	6.4e-80	phaJ	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
OIOLDKHP_01931	4.37e-88	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
OIOLDKHP_01932	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OIOLDKHP_01933	5.99e-137	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
OIOLDKHP_01934	2.15e-62	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OIOLDKHP_01935	1.04e-85	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OIOLDKHP_01936	2.46e-95	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
OIOLDKHP_01937	1.15e-136	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
OIOLDKHP_01938	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OIOLDKHP_01939	1.25e-102	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OIOLDKHP_01940	4.44e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
OIOLDKHP_01941	5.01e-69	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OIOLDKHP_01942	3.33e-91	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
OIOLDKHP_01943	2.94e-229	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
OIOLDKHP_01944	1.36e-40	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
OIOLDKHP_01945	1e-98	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OIOLDKHP_01946	2.96e-92	yqeK	-	-	H	-	-	-	Hydrolase, HD family
OIOLDKHP_01947	2.79e-65	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
OIOLDKHP_01948	2.64e-103	-	-	-	H	-	-	-	Nodulation protein S (NodS)
OIOLDKHP_01949	3.25e-153	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
OIOLDKHP_01950	1.58e-73	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
OIOLDKHP_01951	8.93e-35	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
OIOLDKHP_01952	9.97e-114	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
OIOLDKHP_01953	6.9e-120	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
OIOLDKHP_01954	6.9e-37	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
OIOLDKHP_01955	4.91e-172	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
OIOLDKHP_01956	7.31e-164	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OIOLDKHP_01957	1.82e-49	-	-	-	-	-	-	-	-
OIOLDKHP_01958	4.68e-119	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
OIOLDKHP_01959	9.37e-76	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OIOLDKHP_01960	8.57e-198	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OIOLDKHP_01961	3.59e-285	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OIOLDKHP_01962	1.03e-133	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
OIOLDKHP_01964	1.46e-141	csrR	-	-	K	-	-	-	response regulator