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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HDLNMDOO_00001	4.04e-126	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HDLNMDOO_00002	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HDLNMDOO_00003	2.14e-95	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HDLNMDOO_00004	3.35e-65	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HDLNMDOO_00005	5.17e-167	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HDLNMDOO_00006	6.07e-123	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HDLNMDOO_00007	9.14e-41	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDLNMDOO_00008	4.77e-132	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDLNMDOO_00009	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDLNMDOO_00010	1.24e-282	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HDLNMDOO_00011	1.71e-175	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HDLNMDOO_00012	6.95e-96	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HDLNMDOO_00013	6.93e-292	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HDLNMDOO_00014	3.96e-202	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HDLNMDOO_00015	1.23e-118	-	-	-	S	-	-	-	Acyltransferase family
HDLNMDOO_00016	2.77e-242	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDLNMDOO_00017	2.58e-156	-	-	-	K	-	-	-	LysR substrate binding domain
HDLNMDOO_00019	6.94e-28	-	-	-	-	-	-	-	-
HDLNMDOO_00020	2.81e-74	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HDLNMDOO_00021	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HDLNMDOO_00022	3.64e-63	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HDLNMDOO_00023	1.71e-90	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HDLNMDOO_00024	8.94e-184	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HDLNMDOO_00025	4.16e-133	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HDLNMDOO_00026	2.16e-142	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HDLNMDOO_00027	1.98e-173	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HDLNMDOO_00028	2.53e-156	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HDLNMDOO_00029	2.58e-119	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HDLNMDOO_00030	2.21e-275	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HDLNMDOO_00031	1.35e-46	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HDLNMDOO_00032	1.05e-179	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HDLNMDOO_00033	4.9e-300	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HDLNMDOO_00034	8.09e-72	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HDLNMDOO_00035	1.26e-107	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HDLNMDOO_00036	2.98e-100	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDLNMDOO_00037	4.35e-160	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDLNMDOO_00038	3.38e-116	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HDLNMDOO_00039	6.04e-107	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HDLNMDOO_00040	3.08e-126	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HDLNMDOO_00043	2.08e-148	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HDLNMDOO_00044	5.93e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HDLNMDOO_00045	1.87e-75	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HDLNMDOO_00047	5.44e-87	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HDLNMDOO_00048	2.69e-142	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDLNMDOO_00049	1.85e-136	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HDLNMDOO_00050	1.45e-167	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HDLNMDOO_00051	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HDLNMDOO_00052	1.36e-200	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HDLNMDOO_00053	7.52e-74	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HDLNMDOO_00054	5.11e-171	-	-	-	C	-	-	-	Aldo keto reductase
HDLNMDOO_00055	1.83e-31	-	-	-	K	-	-	-	Transcriptional regulator
HDLNMDOO_00056	1.27e-135	ydhF	-	-	S	-	-	-	Aldo keto reductase
HDLNMDOO_00058	2.14e-99	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HDLNMDOO_00059	4.58e-68	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HDLNMDOO_00060	1.77e-33	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HDLNMDOO_00061	2.54e-170	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HDLNMDOO_00062	1.67e-123	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDLNMDOO_00063	1.96e-106	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HDLNMDOO_00064	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HDLNMDOO_00065	1.42e-264	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HDLNMDOO_00066	6.67e-257	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
HDLNMDOO_00067	1.17e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLNMDOO_00068	3.73e-164	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HDLNMDOO_00069	2.05e-255	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HDLNMDOO_00070	2.93e-129	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
HDLNMDOO_00071	1.27e-49	-	-	-	S	-	-	-	repeat protein
HDLNMDOO_00072	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HDLNMDOO_00074	6.84e-116	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDLNMDOO_00075	8.88e-11	-	-	-	L	-	-	-	Pfam:Integrase_AP2
HDLNMDOO_00077	7.48e-21	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
HDLNMDOO_00078	1.28e-17	-	-	-	-	-	-	-	-
HDLNMDOO_00079	1.13e-23	-	-	-	L	-	-	-	nuclease
HDLNMDOO_00080	1.81e-36	-	-	-	S	-	-	-	Short C-terminal domain
HDLNMDOO_00082	1.62e-49	-	-	-	E	-	-	-	Zn peptidase
HDLNMDOO_00083	2.88e-48	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDLNMDOO_00084	1.85e-12	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
HDLNMDOO_00087	3.29e-109	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDLNMDOO_00088	1.95e-88	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HDLNMDOO_00089	3.97e-56	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HDLNMDOO_00090	7.45e-220	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HDLNMDOO_00091	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDLNMDOO_00092	1.54e-161	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HDLNMDOO_00093	4.31e-127	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HDLNMDOO_00094	2e-88	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDLNMDOO_00095	5.6e-17	-	-	-	-	-	-	-	-
HDLNMDOO_00096	1.01e-182	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HDLNMDOO_00097	1.21e-54	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
HDLNMDOO_00098	8.39e-147	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HDLNMDOO_00099	8.72e-97	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HDLNMDOO_00100	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HDLNMDOO_00101	2.53e-71	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HDLNMDOO_00102	1.03e-71	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
HDLNMDOO_00103	3.83e-56	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HDLNMDOO_00104	1.69e-164	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HDLNMDOO_00105	2.49e-97	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HDLNMDOO_00106	7.51e-257	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HDLNMDOO_00107	1.09e-140	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HDLNMDOO_00108	5.19e-238	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HDLNMDOO_00109	6.09e-109	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HDLNMDOO_00110	3.01e-114	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HDLNMDOO_00111	3.69e-172	-	-	-	K	-	-	-	Transcriptional regulator
HDLNMDOO_00112	1.09e-184	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HDLNMDOO_00113	4.04e-148	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HDLNMDOO_00114	4.06e-218	araT1	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HDLNMDOO_00115	4.96e-111	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HDLNMDOO_00117	3.6e-57	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HDLNMDOO_00118	3.81e-218	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HDLNMDOO_00119	8.9e-48	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HDLNMDOO_00120	1.46e-34	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
HDLNMDOO_00121	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HDLNMDOO_00122	4.34e-51	-	-	-	-	-	-	-	-
HDLNMDOO_00127	2.95e-07	-	-	-	D	-	-	-	nuclear chromosome segregation
HDLNMDOO_00129	2.05e-185	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HDLNMDOO_00130	6.85e-98	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HDLNMDOO_00131	5.44e-130	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HDLNMDOO_00132	1.76e-232	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HDLNMDOO_00133	6.31e-93	-	-	-	L	-	-	-	DNA alkylation repair enzyme
HDLNMDOO_00134	1.72e-174	-	-	-	EG	-	-	-	EamA-like transporter family
HDLNMDOO_00135	2.75e-190	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HDLNMDOO_00136	7.72e-257	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HDLNMDOO_00137	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HDLNMDOO_00138	1.24e-173	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HDLNMDOO_00139	1.34e-220	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HDLNMDOO_00140	4.92e-165	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HDLNMDOO_00141	4.91e-104	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HDLNMDOO_00143	1.79e-119	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HDLNMDOO_00144	1.16e-201	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HDLNMDOO_00145	5.49e-54	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HDLNMDOO_00146	3.26e-255	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HDLNMDOO_00147	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HDLNMDOO_00148	6.47e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HDLNMDOO_00149	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HDLNMDOO_00150	1.7e-211	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HDLNMDOO_00151	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HDLNMDOO_00153	9.22e-53	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HDLNMDOO_00154	1.38e-106	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HDLNMDOO_00155	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDLNMDOO_00156	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDLNMDOO_00157	2.54e-251	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HDLNMDOO_00158	2.07e-52	-	-	-	K	-	-	-	Transcriptional regulator
HDLNMDOO_00159	1.19e-147	-	-	-	S	-	-	-	EDD domain protein, DegV family
HDLNMDOO_00160	3.9e-91	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase, peptidase S26
HDLNMDOO_00161	4.83e-53	-	-	-	S	-	-	-	ASCH
HDLNMDOO_00162	3.72e-236	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HDLNMDOO_00163	6.14e-100	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HDLNMDOO_00164	2.08e-121	-	-	-	EG	-	-	-	EamA-like transporter family
HDLNMDOO_00165	3.32e-105	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type Na efflux pump, permease component
HDLNMDOO_00166	1.62e-140	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	Domain of unknown function (DUF4162)
HDLNMDOO_00167	2.83e-26	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HDLNMDOO_00169	2.02e-48	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HDLNMDOO_00170	1.93e-287	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HDLNMDOO_00171	2.24e-220	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HDLNMDOO_00172	1.73e-78	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphatase family
HDLNMDOO_00173	3.32e-191	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HDLNMDOO_00174	4.73e-40	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDLNMDOO_00175	1.94e-222	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HDLNMDOO_00176	4.83e-273	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDLNMDOO_00178	6.69e-115	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HDLNMDOO_00179	4.63e-199	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HDLNMDOO_00180	4.18e-40	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HDLNMDOO_00181	2.42e-88	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HDLNMDOO_00182	2.93e-196	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HDLNMDOO_00183	4.22e-106	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
HDLNMDOO_00184	1.45e-111	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HDLNMDOO_00185	1.12e-15	-	-	-	M	-	-	-	Lysin motif
HDLNMDOO_00186	1.62e-156	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HDLNMDOO_00187	4.23e-79	-	-	-	S	-	-	-	Helix-turn-helix domain
HDLNMDOO_00188	6.24e-277	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HDLNMDOO_00189	3.42e-59	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HDLNMDOO_00190	1.12e-151	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HDLNMDOO_00191	2.33e-52	-	-	-	-	-	-	-	-
HDLNMDOO_00192	1.81e-84	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDLNMDOO_00195	7.63e-237	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HDLNMDOO_00196	7.24e-263	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HDLNMDOO_00197	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HDLNMDOO_00198	4.75e-215	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HDLNMDOO_00199	5.34e-135	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDLNMDOO_00200	1.5e-87	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDLNMDOO_00201	2.42e-80	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HDLNMDOO_00202	1.21e-99	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain protein
HDLNMDOO_00203	1.34e-166	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDLNMDOO_00204	2.72e-98	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HDLNMDOO_00205	4.83e-259	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HDLNMDOO_00206	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HDLNMDOO_00208	4.32e-103	-	-	-	F	-	-	-	Hydrolase, nudix family
HDLNMDOO_00209	1.34e-73	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HDLNMDOO_00210	2.33e-87	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HDLNMDOO_00211	1.95e-92	-	-	-	M	-	-	-	GNAT acetyltransferase
HDLNMDOO_00213	3.42e-245	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
HDLNMDOO_00214	2.77e-84	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HDLNMDOO_00215	1.15e-11	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HDLNMDOO_00216	4.46e-211	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HDLNMDOO_00217	1.17e-98	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HDLNMDOO_00218	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HDLNMDOO_00219	1.58e-143	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HDLNMDOO_00220	1.77e-158	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HDLNMDOO_00221	1.64e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF441)
HDLNMDOO_00222	8.84e-76	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HDLNMDOO_00223	2.3e-127	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HDLNMDOO_00224	1.55e-78	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HDLNMDOO_00225	9.74e-76	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HDLNMDOO_00226	6.85e-49	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDLNMDOO_00227	6.04e-275	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HDLNMDOO_00228	4.03e-102	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HDLNMDOO_00229	3.63e-155	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HDLNMDOO_00230	7.73e-226	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HDLNMDOO_00231	4.51e-123	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HDLNMDOO_00233	4.7e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HDLNMDOO_00234	1.55e-37	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HDLNMDOO_00235	3.02e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HDLNMDOO_00242	7.66e-80	-	-	-	H	-	-	-	Methyltransferase domain
HDLNMDOO_00243	1.29e-89	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HDLNMDOO_00244	1.58e-51	-	-	-	M	-	-	-	Acetyltransferase (GNAT) family
HDLNMDOO_00246	3.18e-29	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
HDLNMDOO_00247	2.29e-51	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HDLNMDOO_00248	2.66e-106	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HDLNMDOO_00249	2.43e-39	-	-	-	S	-	-	-	CHY zinc finger
HDLNMDOO_00250	7.27e-53	ywnA	-	-	K	-	-	-	Transcriptional regulator
HDLNMDOO_00251	8.23e-105	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HDLNMDOO_00254	2.66e-156	-	-	-	M	-	-	-	Glycosyl transferases group 1
HDLNMDOO_00255	4.57e-79	-	-	-	M	-	-	-	Glycosyl transferases group 1
HDLNMDOO_00256	5.49e-208	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HDLNMDOO_00257	3.08e-183	-	5.1.3.6	-	GM	ko:K08679	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	RmlD substrate binding domain
HDLNMDOO_00258	8.45e-125	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDLNMDOO_00259	4.83e-72	-	-	-	M	-	-	-	Glycosyl transferases group 1
HDLNMDOO_00260	4.98e-147	-	-	-	S	-	-	-	Glycosyltransferase WbsX
HDLNMDOO_00261	6.8e-64	-	-	-	-	-	-	-	-
HDLNMDOO_00263	1.25e-05	-	-	-	M	-	-	-	Glycosyl transferase family 2
HDLNMDOO_00264	3.02e-40	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HDLNMDOO_00265	1.86e-45	rfbF	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
HDLNMDOO_00266	4.36e-91	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HDLNMDOO_00267	2.32e-94	-	-	-	M	-	-	-	glycosyl transferase group 1
HDLNMDOO_00268	7.95e-98	-	-	-	M	-	-	-	glycosyl transferase group 1
HDLNMDOO_00269	3.26e-152	-	-	-	M	-	-	-	Glycosyl transferases group 1
HDLNMDOO_00270	1.52e-35	-	-	-	S	ko:K19429	-	ko00000,ko01000	Bacterial transferase hexapeptide (six repeats)
HDLNMDOO_00271	1.26e-99	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
HDLNMDOO_00272	9.14e-212	epsN	-	-	M	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
HDLNMDOO_00273	5.81e-277	capD	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HDLNMDOO_00274	1.41e-82	-	-	-	D	-	-	-	AAA domain
HDLNMDOO_00275	1.57e-59	-	-	-	M	-	-	-	Chain length determinant protein
HDLNMDOO_00276	1.21e-52	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Protease synthase and sporulation negative regulatory protein pai 1
HDLNMDOO_00277	9.71e-225	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HDLNMDOO_00278	3.87e-82	-	-	-	-	-	-	-	-
HDLNMDOO_00279	4.55e-105	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HDLNMDOO_00280	3.53e-144	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HDLNMDOO_00281	1.84e-76	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HDLNMDOO_00282	4e-240	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HDLNMDOO_00283	5.92e-33	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HDLNMDOO_00284	2.63e-265	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HDLNMDOO_00286	4.18e-80	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HDLNMDOO_00287	1.11e-68	-	-	-	S	-	-	-	Membrane
HDLNMDOO_00288	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HDLNMDOO_00289	1.82e-77	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HDLNMDOO_00290	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HDLNMDOO_00291	8.4e-66	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HDLNMDOO_00292	4.69e-36	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HDLNMDOO_00293	4.61e-153	-	-	-	T	-	-	-	diguanylate cyclase activity
HDLNMDOO_00294	5.73e-276	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HDLNMDOO_00295	2.81e-91	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HDLNMDOO_00296	4.94e-255	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HDLNMDOO_00297	3.46e-255	-	-	-	S	-	-	-	Protein conserved in bacteria
HDLNMDOO_00298	1.26e-235	-	-	-	-	-	-	-	-
HDLNMDOO_00299	7.49e-161	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HDLNMDOO_00300	1.76e-36	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
HDLNMDOO_00302	3.36e-181	pbuO_1	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HDLNMDOO_00303	1.53e-197	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HDLNMDOO_00304	3.48e-134	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HDLNMDOO_00305	1.31e-120	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HDLNMDOO_00306	4.93e-276	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
HDLNMDOO_00307	1.34e-254	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HDLNMDOO_00308	5.29e-178	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HDLNMDOO_00309	1.06e-243	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HDLNMDOO_00310	2.32e-203	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HDLNMDOO_00311	3.05e-48	-	-	-	M	-	-	-	LysM domain
HDLNMDOO_00312	1.38e-25	-	-	-	P	-	-	-	Rhodanese Homology Domain
HDLNMDOO_00313	1.03e-66	-	-	-	M	-	-	-	LysM domain protein
HDLNMDOO_00314	7.86e-116	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HDLNMDOO_00315	2.45e-107	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HDLNMDOO_00317	8.05e-91	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HDLNMDOO_00318	4.52e-131	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDLNMDOO_00319	1.72e-39	-	-	-	S	-	-	-	Belongs to the HesB IscA family
HDLNMDOO_00320	1.38e-83	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
HDLNMDOO_00322	5e-67	-	-	-	K	-	-	-	LysR substrate binding domain
HDLNMDOO_00323	4.16e-150	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HDLNMDOO_00324	2.06e-253	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
HDLNMDOO_00325	3.78e-138	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDLNMDOO_00326	8.2e-65	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HDLNMDOO_00327	2.29e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HDLNMDOO_00328	1.1e-257	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HDLNMDOO_00329	8.98e-202	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HDLNMDOO_00330	4.51e-27	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
HDLNMDOO_00331	1.38e-192	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HDLNMDOO_00332	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDLNMDOO_00333	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDLNMDOO_00334	7.37e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HDLNMDOO_00335	6.48e-89	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HDLNMDOO_00336	3.82e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HDLNMDOO_00337	4.29e-140	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HDLNMDOO_00338	9.4e-148	-	-	-	S	-	-	-	Glycosyl transferase family 2
HDLNMDOO_00339	2.26e-81	-	-	-	D	-	-	-	peptidase
HDLNMDOO_00340	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HDLNMDOO_00341	2.6e-61	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HDLNMDOO_00342	6.14e-52	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HDLNMDOO_00343	2.65e-306	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HDLNMDOO_00344	5.01e-22	yneR	-	-	-	-	-	-	-
HDLNMDOO_00345	3.57e-290	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HDLNMDOO_00346	2.16e-283	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HDLNMDOO_00347	2.34e-136	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HDLNMDOO_00348	2.59e-192	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HDLNMDOO_00349	4.15e-12	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLNMDOO_00350	1.27e-140	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HDLNMDOO_00351	1.86e-212	-	-	-	S	-	-	-	Putative threonine/serine exporter
HDLNMDOO_00352	6.27e-90	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HDLNMDOO_00353	9.44e-121	yicL	-	-	EG	-	-	-	EamA-like transporter family
HDLNMDOO_00354	1.25e-47	pepF	-	-	E	-	-	-	Oligopeptidase F
HDLNMDOO_00355	2.07e-195	pepF	-	-	E	-	-	-	Oligopeptidase F
HDLNMDOO_00356	2.04e-137	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HDLNMDOO_00357	2.85e-224	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HDLNMDOO_00358	4.63e-175	-	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
HDLNMDOO_00359	3.41e-79	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HDLNMDOO_00360	2.51e-31	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HDLNMDOO_00362	1.06e-216	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HDLNMDOO_00363	4.68e-41	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HDLNMDOO_00364	1.08e-269	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLNMDOO_00365	1.11e-286	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
HDLNMDOO_00367	8.29e-107	-	-	-	S	ko:K19175	-	ko00000,ko02048	Domain of unknown function DUF87
HDLNMDOO_00369	4.07e-135	yxeH	-	-	S	-	-	-	hydrolase
HDLNMDOO_00370	2.43e-151	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HDLNMDOO_00371	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDLNMDOO_00372	7.57e-126	yycH	-	-	S	-	-	-	YycH protein
HDLNMDOO_00373	3.35e-100	yycI	-	-	S	-	-	-	YycH protein
HDLNMDOO_00374	4.78e-41	-	-	-	S	-	-	-	YjbR
HDLNMDOO_00375	1.46e-147	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HDLNMDOO_00376	2.33e-187	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HDLNMDOO_00377	7.88e-94	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HDLNMDOO_00378	7.57e-52	-	-	-	GM	-	-	-	NAD(P)H-binding
HDLNMDOO_00379	3.67e-34	-	-	-	K	-	-	-	MarR family transcriptional regulator
HDLNMDOO_00380	5.45e-112	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDLNMDOO_00381	2.54e-57	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HDLNMDOO_00383	1.52e-259	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	glycerol-3-phosphate transporter
HDLNMDOO_00384	1.72e-38	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
HDLNMDOO_00385	3.75e-23	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HDLNMDOO_00386	5.93e-49	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HDLNMDOO_00387	4.34e-93	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HDLNMDOO_00388	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HDLNMDOO_00389	3.45e-36	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HDLNMDOO_00390	8.79e-166	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDLNMDOO_00391	3.2e-164	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HDLNMDOO_00392	1.27e-203	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HDLNMDOO_00393	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HDLNMDOO_00394	5.69e-49	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HDLNMDOO_00395	1.5e-22	-	-	-	-	-	-	-	-
HDLNMDOO_00396	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HDLNMDOO_00397	4.34e-32	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
HDLNMDOO_00398	1.34e-130	-	-	-	G	-	-	-	MucBP domain
HDLNMDOO_00399	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HDLNMDOO_00400	1.72e-252	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HDLNMDOO_00401	1.26e-207	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HDLNMDOO_00402	7.51e-226	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HDLNMDOO_00403	3.21e-139	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HDLNMDOO_00404	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HDLNMDOO_00405	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
HDLNMDOO_00406	3.67e-40	-	-	-	-	-	-	-	-
HDLNMDOO_00407	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HDLNMDOO_00408	1.97e-146	tagH	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HDLNMDOO_00409	3.8e-201	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HDLNMDOO_00410	1.42e-135	yueF	-	-	S	-	-	-	AI-2E family transporter
HDLNMDOO_00411	9.74e-126	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HDLNMDOO_00412	6.34e-242	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDLNMDOO_00413	7.94e-80	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HDLNMDOO_00415	3.84e-31	-	-	-	S	-	-	-	Cytochrome B5
HDLNMDOO_00416	3.8e-53	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HDLNMDOO_00417	4.74e-74	-	-	-	-	-	-	-	-
HDLNMDOO_00418	1.8e-56	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HDLNMDOO_00419	5.69e-197	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
HDLNMDOO_00420	1.84e-116	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HDLNMDOO_00421	5e-64	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HDLNMDOO_00423	1.53e-181	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HDLNMDOO_00424	1.5e-40	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HDLNMDOO_00425	1.32e-282	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HDLNMDOO_00426	5.71e-225	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HDLNMDOO_00427	2.19e-81	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
HDLNMDOO_00428	1.01e-229	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HDLNMDOO_00430	2.54e-98	-	-	-	S	-	-	-	Cell surface protein
HDLNMDOO_00432	5.29e-317	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HDLNMDOO_00433	4.53e-79	-	-	-	-	-	-	-	-
HDLNMDOO_00434	5.02e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HDLNMDOO_00435	3.9e-240	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HDLNMDOO_00436	4.42e-253	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDLNMDOO_00439	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HDLNMDOO_00440	1.75e-57	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HDLNMDOO_00441	1.8e-32	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HDLNMDOO_00442	4.07e-109	-	-	-	F	-	-	-	glutamine amidotransferase
HDLNMDOO_00443	3.45e-261	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HDLNMDOO_00444	5.8e-110	-	-	-	S	-	-	-	hydrolase
HDLNMDOO_00445	1.93e-74	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HDLNMDOO_00446	3.31e-282	-	-	-	L	-	-	-	Probable transposase
HDLNMDOO_00447	2.92e-189	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HDLNMDOO_00448	7.81e-147	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HDLNMDOO_00449	2.2e-187	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HDLNMDOO_00450	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HDLNMDOO_00451	6.09e-96	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HDLNMDOO_00452	3.42e-31	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HDLNMDOO_00453	9.49e-22	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily
HDLNMDOO_00454	7.87e-111	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HDLNMDOO_00455	1.41e-32	-	-	-	-	-	-	-	-
HDLNMDOO_00456	1.47e-30	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HDLNMDOO_00457	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDLNMDOO_00458	1.93e-315	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HDLNMDOO_00459	5.22e-251	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HDLNMDOO_00460	1.37e-245	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HDLNMDOO_00461	9.71e-274	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HDLNMDOO_00462	0.000361	-	-	-	S	-	-	-	Tetratricopeptide repeat
HDLNMDOO_00463	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDLNMDOO_00464	2.18e-146	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HDLNMDOO_00465	2.6e-53	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HDLNMDOO_00466	1.33e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HDLNMDOO_00467	2.49e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HDLNMDOO_00468	2.91e-249	-	-	-	E	ko:K03294	-	ko00000	amino acid
HDLNMDOO_00469	4.4e-78	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HDLNMDOO_00470	1.3e-143	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HDLNMDOO_00471	3.22e-74	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HDLNMDOO_00472	1.99e-37	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HDLNMDOO_00473	1.32e-55	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HDLNMDOO_00474	9.04e-263	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HDLNMDOO_00475	1.51e-53	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HDLNMDOO_00476	1.12e-187	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HDLNMDOO_00477	1.17e-289	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HDLNMDOO_00478	1.2e-128	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HDLNMDOO_00479	9.72e-35	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDLNMDOO_00480	1.08e-180	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HDLNMDOO_00481	1.56e-305	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HDLNMDOO_00482	4.92e-302	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HDLNMDOO_00483	7.35e-69	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HDLNMDOO_00484	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HDLNMDOO_00485	1.23e-72	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HDLNMDOO_00486	1.38e-145	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HDLNMDOO_00487	1.61e-237	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HDLNMDOO_00488	5.23e-114	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HDLNMDOO_00489	2.9e-191	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HDLNMDOO_00490	1.55e-177	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HDLNMDOO_00491	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HDLNMDOO_00492	1.87e-153	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HDLNMDOO_00493	8.22e-30	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HDLNMDOO_00494	8.34e-132	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HDLNMDOO_00495	5.39e-120	-	-	-	M	-	-	-	Phosphotransferase enzyme family
HDLNMDOO_00496	9.47e-58	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HDLNMDOO_00497	6.1e-07	XK27_08315	-	-	M	-	-	-	Sulfatase
HDLNMDOO_00498	1.37e-210	XK27_08315	-	-	M	-	-	-	Sulfatase
HDLNMDOO_00500	6.82e-212	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HDLNMDOO_00501	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HDLNMDOO_00502	1.68e-108	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HDLNMDOO_00503	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDLNMDOO_00504	1.14e-81	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HDLNMDOO_00505	5.94e-107	pncA	-	-	Q	-	-	-	isochorismatase
HDLNMDOO_00506	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HDLNMDOO_00507	3.72e-131	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HDLNMDOO_00508	6.68e-219	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HDLNMDOO_00509	1.7e-55	hxlR	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HDLNMDOO_00510	6.32e-208	-	-	-	C	-	-	-	Luciferase-like monooxygenase
HDLNMDOO_00511	7.62e-234	-	-	-	L	-	-	-	Probable transposase
HDLNMDOO_00512	1.01e-85	-	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HDLNMDOO_00513	4.86e-148	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HDLNMDOO_00514	2.62e-97	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HDLNMDOO_00515	8.37e-76	-	-	-	EG	-	-	-	EamA-like transporter family
HDLNMDOO_00516	7.91e-149	ydbI	-	-	K	-	-	-	AI-2E family transporter
HDLNMDOO_00517	6.34e-217	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HDLNMDOO_00518	3.53e-158	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDLNMDOO_00519	0.000331	-	-	-	S	-	-	-	zinc-ribbon domain
HDLNMDOO_00521	7.9e-135	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HDLNMDOO_00522	6.22e-164	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HDLNMDOO_00523	7.19e-19	-	-	-	-	-	-	-	-
HDLNMDOO_00524	8.82e-133	-	-	-	E	-	-	-	AzlC protein
HDLNMDOO_00525	2.61e-52	-	-	-	S	-	-	-	branched-chain amino acid
HDLNMDOO_00526	2.24e-80	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HDLNMDOO_00527	1.7e-23	-	-	-	-	-	-	-	-
HDLNMDOO_00528	1.06e-73	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
HDLNMDOO_00529	2.39e-27	-	-	-	-	-	-	-	-
HDLNMDOO_00530	1.17e-116	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HDLNMDOO_00531	3.57e-115	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
HDLNMDOO_00532	1.37e-37	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HDLNMDOO_00533	9.59e-104	-	-	-	S	-	-	-	Putative threonine/serine exporter
HDLNMDOO_00534	4.85e-65	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HDLNMDOO_00535	1.52e-157	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HDLNMDOO_00536	3.97e-108	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HDLNMDOO_00537	6.45e-45	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HDLNMDOO_00538	1.09e-28	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDLNMDOO_00539	1.18e-28	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDLNMDOO_00540	6.6e-84	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HDLNMDOO_00542	3.64e-67	ccl	-	-	S	-	-	-	QueT transporter
HDLNMDOO_00543	7.29e-46	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HDLNMDOO_00544	4.48e-131	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HDLNMDOO_00545	1.24e-137	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
HDLNMDOO_00546	3.68e-219	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HDLNMDOO_00547	1.84e-122	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HDLNMDOO_00548	6.38e-110	-	-	-	S	-	-	-	Alpha beta hydrolase
HDLNMDOO_00550	6.24e-192	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDLNMDOO_00551	1.02e-73	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDLNMDOO_00552	2.56e-163	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HDLNMDOO_00553	2.84e-75	-	-	-	S	-	-	-	Protein of unknown function (DUF4256)
HDLNMDOO_00556	1.49e-223	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HDLNMDOO_00557	6.13e-212	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HDLNMDOO_00558	9.5e-231	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HDLNMDOO_00559	4.36e-291	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HDLNMDOO_00560	6.7e-187	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HDLNMDOO_00561	2.36e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HDLNMDOO_00562	1.23e-79	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HDLNMDOO_00563	6.27e-18	-	-	-	-	-	-	-	-
HDLNMDOO_00564	3.81e-37	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HDLNMDOO_00565	2.79e-281	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HDLNMDOO_00566	1.39e-111	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HDLNMDOO_00567	4.7e-192	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HDLNMDOO_00568	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HDLNMDOO_00569	2.33e-57	cps3F	-	-	-	-	-	-	-
HDLNMDOO_00570	2.22e-108	-	-	-	S	-	-	-	Membrane
HDLNMDOO_00571	0.0	-	-	-	E	-	-	-	Amino acid permease
HDLNMDOO_00572	1.69e-291	cadA	-	-	P	-	-	-	P-type ATPase
HDLNMDOO_00573	2.47e-146	degV	-	-	S	-	-	-	EDD domain protein, DegV family
HDLNMDOO_00574	5.86e-189	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HDLNMDOO_00575	1.68e-69	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
HDLNMDOO_00576	3.23e-36	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
HDLNMDOO_00577	6.07e-186	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HDLNMDOO_00578	1.48e-171	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HDLNMDOO_00579	1.18e-103	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HDLNMDOO_00580	1.18e-207	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
HDLNMDOO_00581	6.29e-21	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDLNMDOO_00582	1.04e-284	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HDLNMDOO_00583	6.86e-159	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HDLNMDOO_00584	1.39e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HDLNMDOO_00585	7.78e-154	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HDLNMDOO_00586	2.53e-106	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HDLNMDOO_00587	5.31e-72	lssY	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
HDLNMDOO_00588	7.44e-15	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HDLNMDOO_00589	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HDLNMDOO_00590	7.88e-87	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HDLNMDOO_00591	8.79e-307	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HDLNMDOO_00592	7.95e-263	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HDLNMDOO_00593	2.66e-148	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDLNMDOO_00594	2.13e-163	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HDLNMDOO_00595	2.04e-109	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDLNMDOO_00596	3.63e-45	-	-	-	S	-	-	-	Enterocin A Immunity
HDLNMDOO_00597	1.48e-280	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HDLNMDOO_00598	1.17e-25	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HDLNMDOO_00599	3.38e-95	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HDLNMDOO_00600	1.32e-282	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HDLNMDOO_00601	1.38e-195	yacL	-	-	S	-	-	-	domain protein
HDLNMDOO_00602	7.38e-313	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HDLNMDOO_00603	7.89e-264	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HDLNMDOO_00604	3.45e-73	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HDLNMDOO_00605	1.88e-138	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDLNMDOO_00606	1.93e-92	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HDLNMDOO_00607	3.3e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HDLNMDOO_00608	3.08e-16	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HDLNMDOO_00609	3.13e-109	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HDLNMDOO_00610	2.58e-88	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HDLNMDOO_00611	9.98e-150	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HDLNMDOO_00612	2.21e-97	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HDLNMDOO_00613	2.18e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HDLNMDOO_00614	7.33e-71	-	-	-	-	-	-	-	-
HDLNMDOO_00615	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDLNMDOO_00616	1.1e-203	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDLNMDOO_00617	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDLNMDOO_00618	1.81e-58	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
HDLNMDOO_00619	5.56e-37	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HDLNMDOO_00620	1.11e-96	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HDLNMDOO_00621	2.23e-80	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HDLNMDOO_00622	5.45e-268	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDLNMDOO_00623	3.8e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HDLNMDOO_00624	6.62e-126	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HDLNMDOO_00625	4.16e-39	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HDLNMDOO_00626	2.18e-83	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HDLNMDOO_00627	3.76e-104	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HDLNMDOO_00628	3.85e-52	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HDLNMDOO_00629	9.92e-121	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HDLNMDOO_00630	6.03e-105	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HDLNMDOO_00631	2.82e-178	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HDLNMDOO_00632	3.7e-88	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HDLNMDOO_00633	1.9e-19	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HDLNMDOO_00634	2.51e-206	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HDLNMDOO_00635	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HDLNMDOO_00636	5.32e-127	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HDLNMDOO_00637	4.03e-41	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDLNMDOO_00638	1.7e-46	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HDLNMDOO_00639	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HDLNMDOO_00640	0.0	-	-	-	P	ko:K12952	-	ko00000,ko01000	COG COG0474 Cation transport ATPase
HDLNMDOO_00641	0.0	ydaO	-	-	E	-	-	-	amino acid
HDLNMDOO_00643	7.44e-51	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDLNMDOO_00644	3.64e-135	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDLNMDOO_00645	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HDLNMDOO_00646	3.61e-43	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HDLNMDOO_00647	3.33e-97	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HDLNMDOO_00648	2.23e-209	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDLNMDOO_00649	1.43e-164	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HDLNMDOO_00650	2.76e-91	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HDLNMDOO_00651	8.75e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HDLNMDOO_00652	1.13e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
HDLNMDOO_00653	1.15e-187	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HDLNMDOO_00654	1.69e-153	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HDLNMDOO_00655	3.19e-192	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HDLNMDOO_00656	6.65e-103	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	sugar-binding domain protein
HDLNMDOO_00657	1.23e-119	baeS	-	-	T	-	-	-	Histidine kinase
HDLNMDOO_00658	1.51e-101	yfiK	-	-	K	ko:K02479	-	ko00000,ko02022	Bacterial regulatory proteins, luxR family
HDLNMDOO_00659	1.82e-149	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HDLNMDOO_00660	1.22e-89	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HDLNMDOO_00661	1.29e-51	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDLNMDOO_00662	1.24e-43	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HDLNMDOO_00663	1.41e-246	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HDLNMDOO_00664	5.63e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HDLNMDOO_00665	3.58e-51	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDLNMDOO_00666	9.45e-76	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HDLNMDOO_00667	5.62e-92	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HDLNMDOO_00668	7.88e-116	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HDLNMDOO_00669	1.9e-71	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HDLNMDOO_00670	1.47e-110	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HDLNMDOO_00671	5.71e-28	-	-	-	-	-	-	-	-
HDLNMDOO_00672	2.33e-19	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HDLNMDOO_00673	7.12e-68	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HDLNMDOO_00674	4.8e-43	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
HDLNMDOO_00675	1.2e-144	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HDLNMDOO_00676	3.91e-229	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HDLNMDOO_00677	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDLNMDOO_00678	2.23e-270	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HDLNMDOO_00679	1.88e-185	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HDLNMDOO_00680	1.77e-155	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HDLNMDOO_00681	2.31e-94	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HDLNMDOO_00682	7.67e-71	ymdB	-	-	L	-	-	-	phosphatase homologous to the C-terminal domain of histone macroH2A1
HDLNMDOO_00683	6.71e-32	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
HDLNMDOO_00684	8.72e-58	yyaT	-	-	K	ko:K02348	-	ko00000	protein acetylation
HDLNMDOO_00685	1.29e-11	-	-	-	-	-	-	-	-
HDLNMDOO_00686	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HDLNMDOO_00687	1.53e-278	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HDLNMDOO_00688	3.14e-44	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLNMDOO_00689	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLNMDOO_00690	2.72e-278	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HDLNMDOO_00691	5.55e-188	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HDLNMDOO_00692	3.59e-114	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HDLNMDOO_00693	5.29e-191	hpk31	-	-	T	-	-	-	Histidine kinase
HDLNMDOO_00694	1.21e-145	vanR	-	-	K	-	-	-	response regulator
HDLNMDOO_00695	2.23e-105	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HDLNMDOO_00696	3.83e-116	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HDLNMDOO_00697	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HDLNMDOO_00698	3.28e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HDLNMDOO_00699	2.95e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HDLNMDOO_00700	4.06e-30	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HDLNMDOO_00701	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDLNMDOO_00702	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDLNMDOO_00703	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HDLNMDOO_00704	6.91e-73	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HDLNMDOO_00706	6.07e-152	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HDLNMDOO_00707	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HDLNMDOO_00708	1.12e-198	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HDLNMDOO_00709	5.09e-233	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HDLNMDOO_00710	1.38e-165	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HDLNMDOO_00724	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HDLNMDOO_00725	9.07e-86	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HDLNMDOO_00726	1.18e-258	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HDLNMDOO_00727	6.89e-82	-	-	-	C	-	-	-	FMN binding
HDLNMDOO_00728	2.03e-291	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HDLNMDOO_00730	4.97e-199	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HDLNMDOO_00731	2e-77	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
HDLNMDOO_00732	5.3e-12	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HDLNMDOO_00733	1.36e-103	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HDLNMDOO_00734	5.93e-128	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HDLNMDOO_00735	2.6e-166	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cobalamin-independent synthase, Catalytic domain
HDLNMDOO_00736	1.14e-92	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HDLNMDOO_00737	1.2e-248	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HDLNMDOO_00738	2.56e-203	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HDLNMDOO_00739	1.6e-70	oxyR5	-	-	K	-	-	-	Transcriptional regulator
HDLNMDOO_00740	1.54e-243	-	-	-	C	-	-	-	FMN_bind
HDLNMDOO_00741	3.59e-149	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HDLNMDOO_00742	1.69e-254	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HDLNMDOO_00743	2.4e-177	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HDLNMDOO_00744	1.92e-101	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HDLNMDOO_00745	6e-169	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HDLNMDOO_00746	5.03e-190	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HDLNMDOO_00747	1.82e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
HDLNMDOO_00748	1.25e-27	-	-	-	S	-	-	-	Cupredoxin-like domain
HDLNMDOO_00749	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HDLNMDOO_00750	3.17e-78	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
HDLNMDOO_00751	2.18e-72	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HDLNMDOO_00752	6.95e-112	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HDLNMDOO_00753	1.07e-277	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HDLNMDOO_00754	6.19e-254	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HDLNMDOO_00755	3.98e-189	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDLNMDOO_00756	3.02e-216	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDLNMDOO_00757	6.06e-230	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDLNMDOO_00758	1.99e-196	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDLNMDOO_00759	2.55e-65	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
HDLNMDOO_00760	2.85e-119	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HDLNMDOO_00761	1.08e-117	dedA	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HDLNMDOO_00762	4.54e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HDLNMDOO_00763	1.19e-145	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HDLNMDOO_00764	4.29e-77	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HDLNMDOO_00765	2.63e-72	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HDLNMDOO_00766	1.22e-238	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HDLNMDOO_00767	1.41e-123	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HDLNMDOO_00771	7.13e-18	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
HDLNMDOO_00772	4.34e-36	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HDLNMDOO_00773	7.88e-122	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HDLNMDOO_00774	1.11e-152	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HDLNMDOO_00775	4.05e-130	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HDLNMDOO_00776	4e-153	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HDLNMDOO_00777	4.81e-54	-	-	-	S	-	-	-	VanZ like family
HDLNMDOO_00778	1.26e-202	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HDLNMDOO_00779	9.17e-219	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HDLNMDOO_00781	6.19e-10	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HDLNMDOO_00783	2.81e-95	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDLNMDOO_00784	1.38e-46	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HDLNMDOO_00785	6.12e-83	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HDLNMDOO_00786	4.88e-54	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HDLNMDOO_00787	5.45e-107	-	-	-	S	-	-	-	membrane
HDLNMDOO_00788	1.39e-100	-	-	-	S	-	-	-	VIT family
HDLNMDOO_00789	4.94e-188	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HDLNMDOO_00790	2.26e-73	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HDLNMDOO_00791	6.43e-149	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDLNMDOO_00792	2.14e-146	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDLNMDOO_00793	1.35e-154	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HDLNMDOO_00794	2.58e-150	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HDLNMDOO_00795	7.14e-124	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HDLNMDOO_00796	5.02e-54	yjbH	-	-	Q	-	-	-	Thioredoxin
HDLNMDOO_00797	2.49e-288	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HDLNMDOO_00798	1.87e-85	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HDLNMDOO_00799	1.22e-63	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HDLNMDOO_00800	1.25e-273	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HDLNMDOO_00823	5.21e-226	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HDLNMDOO_00824	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HDLNMDOO_00825	6.58e-245	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HDLNMDOO_00826	1.4e-243	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HDLNMDOO_00827	2.5e-78	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HDLNMDOO_00828	5.46e-105	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HDLNMDOO_00829	4.38e-242	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HDLNMDOO_00830	8.62e-127	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
HDLNMDOO_00831	0.0	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
HDLNMDOO_00833	1.26e-48	-	-	-	-	-	-	-	-
HDLNMDOO_00834	9.26e-87	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HDLNMDOO_00835	1.29e-79	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HDLNMDOO_00836	4.92e-128	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDLNMDOO_00837	1.48e-36	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDLNMDOO_00838	2.98e-131	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HDLNMDOO_00839	3.82e-126	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HDLNMDOO_00840	5.79e-247	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HDLNMDOO_00841	2.34e-60	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HDLNMDOO_00842	5.39e-83	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HDLNMDOO_00843	2.06e-274	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HDLNMDOO_00844	3.84e-159	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HDLNMDOO_00845	4.27e-130	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HDLNMDOO_00846	7.35e-140	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HDLNMDOO_00847	1.27e-289	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HDLNMDOO_00848	2.1e-305	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HDLNMDOO_00849	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HDLNMDOO_00850	1.05e-152	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
HDLNMDOO_00851	3.09e-59	ykuL	-	-	S	-	-	-	CBS domain
HDLNMDOO_00852	1.39e-91	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HDLNMDOO_00853	4.06e-224	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HDLNMDOO_00854	9.23e-115	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HDLNMDOO_00856	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HDLNMDOO_00857	2.92e-28	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HDLNMDOO_00858	6.56e-163	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HDLNMDOO_00859	1.22e-144	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HDLNMDOO_00861	3.15e-69	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HDLNMDOO_00862	1.76e-121	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLNMDOO_00863	1.59e-87	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HDLNMDOO_00864	3.39e-125	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HDLNMDOO_00865	8.2e-131	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HDLNMDOO_00866	2.95e-59	ytpP	-	-	CO	-	-	-	Thioredoxin
HDLNMDOO_00867	2.48e-97	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDLNMDOO_00868	4.87e-298	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HDLNMDOO_00869	1.24e-282	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HDLNMDOO_00870	3.17e-80	phaJ	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
HDLNMDOO_00871	4.37e-88	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HDLNMDOO_00872	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HDLNMDOO_00873	5.99e-137	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HDLNMDOO_00874	2.15e-62	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HDLNMDOO_00875	1.04e-85	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HDLNMDOO_00876	2.46e-95	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HDLNMDOO_00877	1.15e-136	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HDLNMDOO_00878	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HDLNMDOO_00879	1.25e-102	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HDLNMDOO_00880	4.44e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HDLNMDOO_00881	5.01e-69	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HDLNMDOO_00882	3.33e-91	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HDLNMDOO_00883	2.94e-229	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HDLNMDOO_00884	1.93e-40	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HDLNMDOO_00885	1e-98	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HDLNMDOO_00886	2.96e-92	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HDLNMDOO_00887	2.79e-65	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HDLNMDOO_00888	3.06e-102	-	-	-	H	-	-	-	Nodulation protein S (NodS)
HDLNMDOO_00889	2.29e-153	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HDLNMDOO_00890	1.58e-73	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HDLNMDOO_00891	8.93e-35	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HDLNMDOO_00892	9.97e-114	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HDLNMDOO_00893	4.86e-120	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HDLNMDOO_00894	6.9e-37	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HDLNMDOO_00895	4.91e-172	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HDLNMDOO_00896	7.31e-164	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HDLNMDOO_00897	1.82e-49	-	-	-	-	-	-	-	-
HDLNMDOO_00898	4.68e-119	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HDLNMDOO_00899	9.37e-76	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HDLNMDOO_00900	8.57e-198	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HDLNMDOO_00901	3.59e-285	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HDLNMDOO_00902	2.54e-134	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDLNMDOO_00904	1.46e-141	csrR	-	-	K	-	-	-	response regulator
HDLNMDOO_00905	1.17e-217	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDLNMDOO_00906	1.19e-151	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDLNMDOO_00907	1.6e-24	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HDLNMDOO_00908	2.04e-171	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HDLNMDOO_00909	4.27e-143	-	-	-	-	-	-	-	-
HDLNMDOO_00910	1.61e-147	-	-	-	-	-	-	-	-
HDLNMDOO_00911	1.45e-48	-	-	-	S	-	-	-	Protein conserved in bacteria
HDLNMDOO_00912	3.77e-123	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HDLNMDOO_00913	1.4e-60	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HDLNMDOO_00914	7.18e-47	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HDLNMDOO_00915	3.85e-132	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HDLNMDOO_00916	7.01e-183	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDLNMDOO_00917	1.44e-23	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDLNMDOO_00918	8.84e-104	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HDLNMDOO_00919	6.31e-154	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HDLNMDOO_00920	5.91e-65	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HDLNMDOO_00921	3.33e-235	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HDLNMDOO_00922	1.29e-106	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HDLNMDOO_00923	1.82e-41	ynzC	-	-	S	-	-	-	UPF0291 protein
HDLNMDOO_00924	3.98e-36	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
HDLNMDOO_00925	2.28e-118	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HDLNMDOO_00926	2.16e-58	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HDLNMDOO_00927	1.14e-85	yciQ	-	-	P	-	-	-	membrane protein (DUF2207)
HDLNMDOO_00929	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HDLNMDOO_00930	2.55e-49	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HDLNMDOO_00931	1.11e-90	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HDLNMDOO_00932	2.47e-34	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HDLNMDOO_00933	8.22e-203	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HDLNMDOO_00934	1.19e-59	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HDLNMDOO_00935	6.17e-24	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HDLNMDOO_00936	6.09e-141	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HDLNMDOO_00937	1.56e-257	ynbB	-	-	P	-	-	-	aluminum resistance
HDLNMDOO_00938	1.3e-59	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HDLNMDOO_00939	3.28e-312	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HDLNMDOO_00941	6.13e-47	-	2.1.1.63	-	H	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HDLNMDOO_00942	8.28e-64	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HDLNMDOO_00943	1.02e-147	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HDLNMDOO_00944	8.26e-105	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HDLNMDOO_00945	2.86e-134	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HDLNMDOO_00946	1.58e-131	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HDLNMDOO_00947	2.52e-196	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HDLNMDOO_00948	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HDLNMDOO_00949	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDLNMDOO_00950	4.7e-85	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HDLNMDOO_00951	1.25e-216	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HDLNMDOO_00952	3.32e-53	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HDLNMDOO_00953	2.85e-35	ylxQ	-	-	J	-	-	-	ribosomal protein
HDLNMDOO_00954	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HDLNMDOO_00955	2.58e-73	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HDLNMDOO_00956	1.65e-151	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HDLNMDOO_00957	1.83e-120	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HDLNMDOO_00958	1.51e-165	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HDLNMDOO_00959	3.65e-75	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HDLNMDOO_00960	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HDLNMDOO_00961	5.74e-218	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HDLNMDOO_00962	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HDLNMDOO_00964	8.61e-258	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDLNMDOO_00965	7.44e-153	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDLNMDOO_00966	1.83e-41	-	-	-	-	-	-	-	-
HDLNMDOO_00967	2.05e-138	ampC	-	-	V	-	-	-	Beta-lactamase
HDLNMDOO_00968	9.35e-141	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HDLNMDOO_00969	1.79e-278	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HDLNMDOO_00970	1.19e-111	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HDLNMDOO_00971	1.04e-230	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HDLNMDOO_00972	7.51e-114	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HDLNMDOO_00973	1.9e-171	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HDLNMDOO_00974	2.18e-129	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HDLNMDOO_00975	2.33e-124	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HDLNMDOO_00976	1.39e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDLNMDOO_00977	2.96e-57	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HDLNMDOO_00978	1.62e-73	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDLNMDOO_00979	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HDLNMDOO_00980	3.29e-181	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HDLNMDOO_00981	8.04e-313	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HDLNMDOO_00982	3.59e-69	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HDLNMDOO_00983	8.32e-21	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HDLNMDOO_00984	2.53e-261	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDLNMDOO_00985	2.82e-214	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HDLNMDOO_00986	3.25e-36	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HDLNMDOO_00987	2.21e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HDLNMDOO_00988	2.21e-236	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HDLNMDOO_00989	7.81e-35	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HDLNMDOO_00990	4.64e-113	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HDLNMDOO_00991	7.25e-214	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HDLNMDOO_00992	1.72e-160	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HDLNMDOO_00993	3.43e-222	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HDLNMDOO_00994	4.49e-94	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HDLNMDOO_00995	5.79e-77	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDLNMDOO_00996	3.39e-109	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
HDLNMDOO_00997	6.73e-72	-	-	-	-	-	-	-	-
HDLNMDOO_00998	7.59e-88	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HDLNMDOO_00999	7.7e-190	XK27_08315	-	-	M	-	-	-	Sulfatase
HDLNMDOO_01000	2.91e-150	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
HDLNMDOO_01001	4.55e-20	-	-	-	-	-	-	-	-
HDLNMDOO_01002	5.46e-58	cps3I	-	-	G	-	-	-	Acyltransferase family
HDLNMDOO_01003	7.43e-186	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HDLNMDOO_01004	2.83e-65	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HDLNMDOO_01005	7.22e-197	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HDLNMDOO_01006	1.23e-85	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HDLNMDOO_01007	3.74e-119	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HDLNMDOO_01008	9.26e-205	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HDLNMDOO_01009	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HDLNMDOO_01010	2.89e-92	-	-	-	G	-	-	-	Peptidase_C39 like family
HDLNMDOO_01012	4.78e-263	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HDLNMDOO_01013	1.17e-77	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLNMDOO_01014	4.2e-144	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
HDLNMDOO_01015	2.16e-192	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HDLNMDOO_01016	2.82e-88	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HDLNMDOO_01017	4.88e-66	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HDLNMDOO_01018	3.08e-135	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HDLNMDOO_01019	1.41e-220	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HDLNMDOO_01020	6.23e-257	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HDLNMDOO_01021	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HDLNMDOO_01022	1.01e-236	noxE	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HDLNMDOO_01023	1.66e-51	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HDLNMDOO_01024	3.9e-134	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDLNMDOO_01025	7.11e-129	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDLNMDOO_01026	4.77e-122	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HDLNMDOO_01027	3.75e-49	-	-	-	K	-	-	-	Transcriptional regulator
HDLNMDOO_01028	6.4e-138	-	-	-	P	-	-	-	Integral membrane protein TerC family
HDLNMDOO_01029	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HDLNMDOO_01030	1.63e-85	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDLNMDOO_01031	2.44e-235	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HDLNMDOO_01032	5.09e-56	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HDLNMDOO_01033	1.09e-121	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLNMDOO_01035	1.23e-37	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HDLNMDOO_01036	4.09e-124	-	-	-	-	-	-	-	-
HDLNMDOO_01037	9.64e-17	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
HDLNMDOO_01040	1.78e-19	-	-	-	S	-	-	-	head morphogenesis protein, SPP1 gp7 family
HDLNMDOO_01041	3.3e-236	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HDLNMDOO_01042	3.77e-102	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HDLNMDOO_01043	2.27e-86	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HDLNMDOO_01044	5.79e-54	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HDLNMDOO_01045	3.68e-144	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HDLNMDOO_01046	5.48e-96	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HDLNMDOO_01047	2.39e-258	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HDLNMDOO_01048	1.09e-191	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HDLNMDOO_01049	1.74e-80	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HDLNMDOO_01050	4.37e-70	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HDLNMDOO_01051	2.04e-114	nanK	-	-	GK	-	-	-	ROK family
HDLNMDOO_01052	4.39e-162	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HDLNMDOO_01053	4.52e-118	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HDLNMDOO_01054	6.64e-95	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HDLNMDOO_01055	2.11e-44	yphA	-	-	GM	-	-	-	NAD dependent epimerase/dehydratase family
HDLNMDOO_01056	2.16e-271	potE	-	-	E	-	-	-	Amino Acid
HDLNMDOO_01057	1.16e-08	-	-	-	-	-	-	-	-
HDLNMDOO_01058	5.44e-43	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HDLNMDOO_01059	2.94e-289	fusA1	-	-	J	-	-	-	elongation factor G
HDLNMDOO_01061	0.000189	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
HDLNMDOO_01063	6.5e-121	-	-	-	L	-	-	-	PLD-like domain
HDLNMDOO_01064	4.55e-68	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HDLNMDOO_01065	3.54e-59	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
HDLNMDOO_01066	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HDLNMDOO_01067	7.86e-140	dat	2.6.1.21	-	EH	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	PFAM aminotransferase, class IV
HDLNMDOO_01068	3.07e-06	sdpI	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HDLNMDOO_01069	1.26e-84	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HDLNMDOO_01070	1.37e-61	hmpT	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HDLNMDOO_01071	2.78e-54	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
HDLNMDOO_01073	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HDLNMDOO_01074	8.17e-123	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLNMDOO_01076	1.11e-93	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDLNMDOO_01077	6.69e-154	ytbE	-	-	S	-	-	-	reductase
HDLNMDOO_01078	1.22e-57	ytcD	-	-	K	-	-	-	HxlR-like helix-turn-helix
HDLNMDOO_01079	1.78e-130	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HDLNMDOO_01080	4.78e-86	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter
HDLNMDOO_01081	1.49e-208	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HDLNMDOO_01082	5.58e-69	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HDLNMDOO_01083	2.53e-60	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HDLNMDOO_01084	4.63e-30	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HDLNMDOO_01085	2.6e-191	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HDLNMDOO_01087	2.35e-51	-	-	-	K	-	-	-	LytTr DNA-binding domain
HDLNMDOO_01088	1.53e-143	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HDLNMDOO_01089	9.59e-265	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HDLNMDOO_01090	5.22e-21	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HDLNMDOO_01091	4.03e-153	npr	1.11.1.1	-	S	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HDLNMDOO_01092	1.16e-136	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
HDLNMDOO_01093	2.51e-105	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HDLNMDOO_01094	4.69e-106	-	-	-	C	-	-	-	nitroreductase
HDLNMDOO_01095	3.22e-168	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HDLNMDOO_01096	5.23e-119	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDLNMDOO_01097	1.87e-188	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDLNMDOO_01098	1.81e-136	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HDLNMDOO_01099	3.1e-178	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HDLNMDOO_01100	3.59e-60	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
HDLNMDOO_01101	2.91e-76	yphH	-	-	S	-	-	-	Cupin domain
HDLNMDOO_01102	3.04e-59	-	-	-	C	-	-	-	Flavodoxin
HDLNMDOO_01103	1.12e-72	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDLNMDOO_01104	2.22e-131	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
HDLNMDOO_01105	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HDLNMDOO_01106	6.13e-286	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HDLNMDOO_01107	6.58e-70	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDLNMDOO_01108	2.49e-87	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HDLNMDOO_01109	1.93e-138	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLNMDOO_01110	9.74e-147	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HDLNMDOO_01111	1.12e-168	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HDLNMDOO_01112	4.18e-46	-	-	-	-	-	-	-	-
HDLNMDOO_01113	1.17e-218	repA	-	-	S	-	-	-	Replication initiator protein A
HDLNMDOO_01114	5.58e-170	-	-	-	S	-	-	-	Fic/DOC family
HDLNMDOO_01115	1.07e-53	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
HDLNMDOO_01116	1.99e-35	-	-	-	-	-	-	-	-
HDLNMDOO_01117	5.46e-161	-	-	-	S	-	-	-	protein conserved in bacteria
HDLNMDOO_01118	2.96e-55	-	-	-	-	-	-	-	-
HDLNMDOO_01119	6.89e-37	-	-	-	-	-	-	-	-
HDLNMDOO_01120	0.0	-	-	-	L	-	-	-	MobA MobL family protein
HDLNMDOO_01121	7.09e-57	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HDLNMDOO_01122	3.11e-249	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HDLNMDOO_01123	4.12e-119	-	-	-	-	-	-	-	-
HDLNMDOO_01124	1.38e-93	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
HDLNMDOO_01125	1.19e-74	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HDLNMDOO_01126	1.56e-35	-	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
HDLNMDOO_01127	2.24e-15	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HDLNMDOO_01128	8.52e-200	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HDLNMDOO_01129	8.14e-62	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HDLNMDOO_01130	2.44e-104	-	-	-	-	-	-	-	-
HDLNMDOO_01131	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HDLNMDOO_01137	1.16e-16	xre	-	-	K	-	-	-	sequence-specific DNA binding
HDLNMDOO_01139	3.92e-41	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDLNMDOO_01141	1.61e-146	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDLNMDOO_01143	7.08e-105	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HDLNMDOO_01144	1.49e-121	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
HDLNMDOO_01145	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HDLNMDOO_01146	8.77e-205	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HDLNMDOO_01147	4.95e-81	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HDLNMDOO_01148	1.03e-110	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HDLNMDOO_01149	7.39e-104	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDLNMDOO_01150	1.44e-10	-	-	-	K	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HDLNMDOO_01151	2.17e-35	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HDLNMDOO_01152	5.85e-168	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HDLNMDOO_01153	8.29e-143	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HDLNMDOO_01154	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HDLNMDOO_01157	2.44e-89	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HDLNMDOO_01158	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
HDLNMDOO_01160	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HDLNMDOO_01161	6.42e-125	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HDLNMDOO_01162	3.66e-205	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
HDLNMDOO_01163	4.79e-141	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HDLNMDOO_01164	7.16e-94	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HDLNMDOO_01165	7.01e-57	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HDLNMDOO_01166	1.93e-106	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HDLNMDOO_01167	7.39e-173	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HDLNMDOO_01168	2.21e-47	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HDLNMDOO_01169	1.09e-80	mipB	2.2.1.2	-	H	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
HDLNMDOO_01170	1.27e-272	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HDLNMDOO_01171	1.62e-186	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HDLNMDOO_01172	1.78e-186	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HDLNMDOO_01173	2.07e-106	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HDLNMDOO_01174	3.54e-140	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HDLNMDOO_01175	2.51e-192	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HDLNMDOO_01176	2.65e-35	-	-	-	-	-	-	-	-
HDLNMDOO_01177	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HDLNMDOO_01178	1.01e-77	-	-	-	T	-	-	-	Universal stress protein family
HDLNMDOO_01180	5.42e-272	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDLNMDOO_01181	3.5e-214	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HDLNMDOO_01185	1.64e-182	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HDLNMDOO_01186	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HDLNMDOO_01187	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDLNMDOO_01188	1.39e-204	camS	-	-	S	-	-	-	sex pheromone
HDLNMDOO_01189	1.34e-50	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDLNMDOO_01190	4.18e-294	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HDLNMDOO_01191	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDLNMDOO_01192	8.82e-184	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HDLNMDOO_01193	6.09e-265	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDLNMDOO_01194	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
HDLNMDOO_01195	1.65e-36	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HDLNMDOO_01196	1.81e-46	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HDLNMDOO_01197	1.29e-57	-	-	-	K	ko:K07727	-	ko00000,ko03000	addiction module antidote protein HigA
HDLNMDOO_01198	6.42e-17	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HDLNMDOO_01200	7.56e-17	-	-	-	-	-	-	-	-
HDLNMDOO_01201	6.72e-27	-	-	-	-	-	-	-	-
HDLNMDOO_01202	1.32e-20	-	-	-	-	-	-	-	-
HDLNMDOO_01206	3.99e-205	-	-	-	D	-	-	-	AAA domain
HDLNMDOO_01207	2.5e-131	-	-	-	S	-	-	-	AAA domain
HDLNMDOO_01208	2.98e-65	-	-	-	-	-	-	-	-
HDLNMDOO_01209	1.89e-51	-	-	-	-	-	-	-	-
HDLNMDOO_01210	1.5e-99	-	-	-	-	-	-	-	-
HDLNMDOO_01211	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HDLNMDOO_01212	0.0	-	-	-	L	-	-	-	Primase C terminal 2 (PriCT-2)
HDLNMDOO_01213	1.61e-58	-	-	-	S	-	-	-	magnesium ion binding
HDLNMDOO_01223	1.53e-27	-	-	-	-	-	-	-	-
HDLNMDOO_01224	2.75e-209	-	-	-	S	ko:K06909	-	ko00000	Terminase RNAseH like domain
HDLNMDOO_01225	2.25e-175	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HDLNMDOO_01226	1.59e-118	-	-	-	S	-	-	-	Phage minor capsid protein 2
HDLNMDOO_01229	1.03e-28	-	-	-	S	-	-	-	Phage minor structural protein GP20
HDLNMDOO_01230	2.89e-123	-	-	-	S	-	-	-	T=7 icosahedral viral capsid
HDLNMDOO_01232	2.65e-39	-	-	-	S	-	-	-	Minor capsid protein
HDLNMDOO_01235	5.53e-32	-	-	-	N	-	-	-	domain, Protein
HDLNMDOO_01237	3.88e-50	-	-	-	S	-	-	-	Bacteriophage Gp15 protein
HDLNMDOO_01238	3.06e-113	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HDLNMDOO_01240	3.62e-71	rny	-	-	D	ko:K12088,ko:K18682	ko03018,ko05120,map03018,map05120	ko00000,ko00001,ko00002,ko01000,ko02044,ko03019	peptidase
HDLNMDOO_01242	1.37e-89	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HDLNMDOO_01247	3.42e-15	-	-	-	S	-	-	-	Bacteriophage holin
HDLNMDOO_01248	1.33e-164	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HDLNMDOO_01252	1.25e-153	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HDLNMDOO_01253	1.06e-236	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HDLNMDOO_01254	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HDLNMDOO_01255	2.44e-49	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HDLNMDOO_01256	1.57e-78	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HDLNMDOO_01257	4.23e-44	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HDLNMDOO_01258	3.67e-17	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HDLNMDOO_01259	3.86e-20	cvpA	-	-	S	-	-	-	Colicin V production protein
HDLNMDOO_01260	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HDLNMDOO_01261	5.23e-54	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HDLNMDOO_01262	3.55e-79	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HDLNMDOO_01263	4.41e-94	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HDLNMDOO_01264	2.57e-53	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HDLNMDOO_01267	8.53e-179	-	1.1.1.29	-	C	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDLNMDOO_01268	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HDLNMDOO_01269	2.73e-271	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HDLNMDOO_01270	4.16e-254	oatA	-	-	I	-	-	-	Acyltransferase
HDLNMDOO_01271	1.68e-22	-	-	-	-	-	-	-	-
HDLNMDOO_01273	3.04e-179	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HDLNMDOO_01274	3.93e-127	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
HDLNMDOO_01275	1.17e-266	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HDLNMDOO_01276	4.3e-104	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HDLNMDOO_01277	0.0	-	-	-	S	-	-	-	membrane
HDLNMDOO_01278	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HDLNMDOO_01279	3e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HDLNMDOO_01280	5.95e-96	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HDLNMDOO_01282	5.94e-158	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HDLNMDOO_01283	5.17e-253	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HDLNMDOO_01284	4.17e-70	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HDLNMDOO_01285	6.35e-97	uspA	-	-	T	-	-	-	universal stress protein
HDLNMDOO_01287	7.05e-242	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HDLNMDOO_01288	4.14e-31	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HDLNMDOO_01289	5.9e-130	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HDLNMDOO_01290	1.81e-72	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HDLNMDOO_01291	1.4e-224	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HDLNMDOO_01292	5.87e-204	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HDLNMDOO_01293	1.44e-248	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HDLNMDOO_01294	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HDLNMDOO_01295	3.44e-169	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HDLNMDOO_01296	1.31e-101	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HDLNMDOO_01297	1.96e-29	-	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
HDLNMDOO_01298	2.35e-207	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HDLNMDOO_01299	1.64e-121	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HDLNMDOO_01300	6.58e-71	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HDLNMDOO_01301	3.56e-98	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HDLNMDOO_01302	7.95e-163	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HDLNMDOO_01303	3.02e-122	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HDLNMDOO_01304	2.01e-115	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDLNMDOO_01305	3.24e-138	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HDLNMDOO_01306	4.54e-124	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HDLNMDOO_01307	1.16e-05	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HDLNMDOO_01308	5.43e-196	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HDLNMDOO_01310	5.35e-82	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HDLNMDOO_01311	3.67e-180	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HDLNMDOO_01312	1.05e-13	ftsL	-	-	D	-	-	-	Essential cell division protein
HDLNMDOO_01313	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HDLNMDOO_01314	5.17e-172	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HDLNMDOO_01315	2.97e-233	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HDLNMDOO_01316	8.63e-195	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HDLNMDOO_01317	1.83e-75	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HDLNMDOO_01318	6.07e-240	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HDLNMDOO_01319	1.29e-228	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HDLNMDOO_01320	8.14e-43	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HDLNMDOO_01321	8.19e-27	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HDLNMDOO_01322	5.69e-104	ylmH	-	-	S	-	-	-	S4 domain protein
HDLNMDOO_01323	1.14e-91	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HDLNMDOO_01324	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HDLNMDOO_01325	1.55e-84	-	-	-	D	-	-	-	Peptidase family M23
HDLNMDOO_01327	9.89e-172	tetA	-	-	EGP	ko:K08151,ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko01504,ko02000	Major facilitator Superfamily
HDLNMDOO_01328	2.51e-43	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
HDLNMDOO_01329	1.26e-268	potE	-	-	E	-	-	-	Amino Acid
HDLNMDOO_01330	1.64e-239	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HDLNMDOO_01331	3.91e-143	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDLNMDOO_01332	8.17e-51	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HDLNMDOO_01333	7.86e-171	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HDLNMDOO_01334	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HDLNMDOO_01336	9.67e-20	-	-	-	-	-	-	-	-
HDLNMDOO_01337	5.78e-104	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HDLNMDOO_01338	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HDLNMDOO_01341	4.13e-64	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HDLNMDOO_01342	9.7e-62	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HDLNMDOO_01351	2.04e-25	ps105	-	-	-	-	-	-	-
HDLNMDOO_01352	6.56e-50	blpT	-	-	-	-	-	-	-
HDLNMDOO_01353	1.47e-113	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HDLNMDOO_01354	7.79e-18	-	-	-	-	-	-	-	-
HDLNMDOO_01356	3.33e-265	arsR	-	-	K	-	-	-	DNA-binding transcription factor activity
HDLNMDOO_01357	3.68e-124	-	-	-	K	-	-	-	Transcriptional regulator
HDLNMDOO_01358	3.54e-42	-	-	-	L	ko:K07483	-	ko00000	Transposase
HDLNMDOO_01359	1.63e-63	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HDLNMDOO_01360	6.76e-54	-	-	-	S	-	-	-	Signal peptide protein, YSIRK family
HDLNMDOO_01361	1.24e-98	saeR	-	-	K	ko:K10682	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HDLNMDOO_01362	9.8e-113	saeS	2.7.13.3	-	T	ko:K10681	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HDLNMDOO_01363	4.79e-32	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDLNMDOO_01364	1.79e-140	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HDLNMDOO_01365	1.8e-58	pncA	-	-	Q	-	-	-	Isochorismatase family
HDLNMDOO_01366	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDLNMDOO_01367	4.85e-168	-	-	-	F	-	-	-	NUDIX domain
HDLNMDOO_01368	1.19e-201	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDLNMDOO_01369	1.8e-132	potC	-	-	U	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDLNMDOO_01370	3.85e-153	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDLNMDOO_01371	6.33e-212	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HDLNMDOO_01372	3.81e-129	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HDLNMDOO_01373	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HDLNMDOO_01374	4.13e-296	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HDLNMDOO_01377	6.95e-22	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HDLNMDOO_01378	3.71e-09	-	-	-	S	-	-	-	Putative adhesin
HDLNMDOO_01379	3.42e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HDLNMDOO_01380	1.47e-50	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
HDLNMDOO_01381	2.09e-131	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HDLNMDOO_01382	1.14e-310	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HDLNMDOO_01383	2.12e-227	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLNMDOO_01384	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HDLNMDOO_01385	2.4e-191	-	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HDLNMDOO_01386	2.42e-200	-	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HDLNMDOO_01387	2.94e-168	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HDLNMDOO_01388	9.31e-122	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HDLNMDOO_01389	2.4e-141	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HDLNMDOO_01390	1.85e-96	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HDLNMDOO_01391	2.17e-240	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HDLNMDOO_01392	2.67e-45	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HDLNMDOO_01393	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HDLNMDOO_01394	3.49e-149	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HDLNMDOO_01395	1.13e-75	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HDLNMDOO_01396	1.71e-97	azlC	-	-	E	-	-	-	branched-chain amino acid
HDLNMDOO_01397	1.42e-42	-	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HDLNMDOO_01398	2.21e-73	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDLNMDOO_01399	1.8e-69	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HDLNMDOO_01401	1.13e-54	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HDLNMDOO_01402	1.71e-316	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HDLNMDOO_01403	1.86e-165	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HDLNMDOO_01404	3.1e-307	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDLNMDOO_01405	3.32e-113	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HDLNMDOO_01406	9.25e-124	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HDLNMDOO_01407	4.28e-115	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HDLNMDOO_01410	4.29e-260	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HDLNMDOO_01412	3.17e-51	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HDLNMDOO_01413	6.65e-41	-	-	-	-	-	-	-	-
HDLNMDOO_01415	6.36e-14	-	-	-	S	-	-	-	Domain of unknown function (DUF4176)
HDLNMDOO_01419	8.64e-128	-	-	-	EGP	-	-	-	Major Facilitator
HDLNMDOO_01420	1.68e-133	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HDLNMDOO_01421	4.92e-298	-	-	-	EGP	-	-	-	Major Facilitator
HDLNMDOO_01427	2.34e-16	xre	-	-	K	-	-	-	sequence-specific DNA binding
HDLNMDOO_01429	1.33e-16	-	-	-	K	-	-	-	Transcriptional regulator, Cro CI family
HDLNMDOO_01430	3.75e-200	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HDLNMDOO_01431	3.51e-158	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HDLNMDOO_01432	1.13e-68	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HDLNMDOO_01433	3.84e-26	-	-	-	L	-	-	-	PLD-like domain
HDLNMDOO_01437	3.24e-142	-	-	-	L	-	-	-	Initiator Replication protein
HDLNMDOO_01438	5.2e-45	-	-	-	S	-	-	-	Replication initiator protein A (RepA) N-terminus
HDLNMDOO_01439	9.04e-172	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDLNMDOO_01440	5.43e-102	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HDLNMDOO_01441	6.78e-16	licT	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HDLNMDOO_01442	1.31e-160	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HDLNMDOO_01444	2.21e-47	-	-	-	-	-	-	-	-
HDLNMDOO_01445	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HDLNMDOO_01446	2.18e-52	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
HDLNMDOO_01447	2.79e-17	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HDLNMDOO_01455	3.58e-158	yvgN	-	-	C	-	-	-	Aldo keto reductase
HDLNMDOO_01456	3.98e-155	yvgN	-	-	C	-	-	-	Aldo keto reductase
HDLNMDOO_01457	8.22e-90	rdrB	-	-	K	ko:K02444,ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HDLNMDOO_01458	1.28e-60	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDLNMDOO_01459	9.32e-55	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HDLNMDOO_01460	3.52e-287	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HDLNMDOO_01462	1.4e-133	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
HDLNMDOO_01464	9.99e-40	-	-	-	S	-	-	-	COG NOG19168 non supervised orthologous group
HDLNMDOO_01465	2.89e-240	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDLNMDOO_01467	3.92e-135	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDLNMDOO_01469	1.06e-64	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HDLNMDOO_01471	7.63e-69	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
HDLNMDOO_01472	1.29e-226	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	Adenine specific DNA methylase Mod
HDLNMDOO_01473	6.79e-219	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
HDLNMDOO_01474	0.0	sthIR	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
HDLNMDOO_01477	1.25e-14	-	-	-	-	-	-	-	-
HDLNMDOO_01478	1.53e-62	-	-	-	L	ko:K07451,ko:K07453	-	ko00000,ko01000,ko02048	HNH endonuclease
HDLNMDOO_01481	2.73e-215	potE2	-	-	E	ko:K03294	-	ko00000	amino acid
HDLNMDOO_01482	2.15e-90	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HDLNMDOO_01483	2.43e-85	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HDLNMDOO_01484	1.92e-148	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HDLNMDOO_01485	2.29e-75	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HDLNMDOO_01486	8.07e-103	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
HDLNMDOO_01487	4.15e-61	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HDLNMDOO_01490	1.73e-49	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HDLNMDOO_01491	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HDLNMDOO_01492	1.22e-66	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
HDLNMDOO_01493	2.01e-76	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HDLNMDOO_01494	2.85e-197	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HDLNMDOO_01495	8.45e-120	-	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
HDLNMDOO_01496	1.43e-160	-	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
HDLNMDOO_01497	1.54e-55	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HDLNMDOO_01498	2.64e-26	tnp	-	-	-	ko:K07498	-	ko00000	-
HDLNMDOO_01499	1.32e-33	-	-	-	L	ko:K07498	-	ko00000	Transposase
HDLNMDOO_01500	3.43e-45	-	-	-	P	-	-	-	Heavy-metal-associated domain
HDLNMDOO_01501	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
HDLNMDOO_01502	1.2e-28	-	-	-	L	ko:K07483	-	ko00000	PFAM transposase IS3 IS911 family protein
HDLNMDOO_01503	6.56e-52	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HDLNMDOO_01504	3.04e-44	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HDLNMDOO_01505	3.08e-167	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HDLNMDOO_01506	1.62e-121	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HDLNMDOO_01507	6.52e-90	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HDLNMDOO_01508	3.01e-176	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HDLNMDOO_01509	4.95e-148	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HDLNMDOO_01510	1.39e-269	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HDLNMDOO_01511	2.97e-175	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HDLNMDOO_01512	2.98e-90	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HDLNMDOO_01513	5.14e-180	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase family
HDLNMDOO_01517	4.9e-24	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDLNMDOO_01518	3.33e-100	bsh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HDLNMDOO_01519	1.06e-13	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HDLNMDOO_01520	2.12e-48	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HDLNMDOO_01521	2.37e-97	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HDLNMDOO_01522	1.22e-72	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDLNMDOO_01523	5.51e-67	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HDLNMDOO_01524	6.88e-100	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HDLNMDOO_01525	1.15e-126	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HDLNMDOO_01526	8.24e-99	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HDLNMDOO_01527	1.42e-34	-	-	-	-	-	-	-	-
HDLNMDOO_01528	5.32e-18	-	-	-	-	-	-	-	-
HDLNMDOO_01529	1.07e-141	rssA	-	-	S	-	-	-	Phospholipase, patatin family
HDLNMDOO_01530	5.49e-175	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDLNMDOO_01531	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HDLNMDOO_01532	1.25e-63	-	-	-	S	-	-	-	VIT family
HDLNMDOO_01533	9.19e-304	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HDLNMDOO_01534	1.15e-53	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HDLNMDOO_01535	1.39e-182	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HDLNMDOO_01536	1.3e-180	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HDLNMDOO_01537	7.42e-148	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HDLNMDOO_01538	6.35e-281	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HDLNMDOO_01539	9.03e-317	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
HDLNMDOO_01540	1.1e-172	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HDLNMDOO_01541	3.14e-147	ddh	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDLNMDOO_01545	3.99e-75	-	-	-	S	ko:K06919	-	ko00000	DNA primase
HDLNMDOO_01546	5.57e-80	-	-	-	V	-	-	-	HNH endonuclease
HDLNMDOO_01548	2.4e-41	-	-	-	L	-	-	-	MULE transposase domain
HDLNMDOO_01549	6.74e-47	SERPINA3	-	-	V	ko:K04525	-	ko00000	Serine protease inhibitor
HDLNMDOO_01550	3.51e-74	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
HDLNMDOO_01551	2.43e-64	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HDLNMDOO_01552	2.71e-176	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDLNMDOO_01553	3.04e-33	-	-	-	-	-	-	-	-
HDLNMDOO_01554	6.22e-80	-	-	-	-	-	-	-	-
HDLNMDOO_01556	2.55e-26	recD2_2	3.1.11.5	-	L	ko:K01144	-	ko00000,ko01000	PIF1-like helicase
HDLNMDOO_01558	9.35e-63	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
HDLNMDOO_01560	6.71e-110	-	-	-	S	-	-	-	overlaps another CDS with the same product name
HDLNMDOO_01561	9.11e-156	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HDLNMDOO_01562	3.51e-124	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HDLNMDOO_01563	3.99e-43	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
HDLNMDOO_01564	1.25e-19	-	-	-	S	-	-	-	Belongs to the UPF0173 family
HDLNMDOO_01565	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HDLNMDOO_01566	3.47e-98	-	-	-	F	-	-	-	Phosphorylase superfamily
HDLNMDOO_01567	1.82e-33	-	-	-	-	-	-	-	-
HDLNMDOO_01568	8.27e-141	dkgB	-	-	S	-	-	-	reductase
HDLNMDOO_01569	6.97e-27	rimL	1.1.1.25	-	J	ko:K00014,ko:K03817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HDLNMDOO_01570	2.25e-216	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDLNMDOO_01571	7.9e-257	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HDLNMDOO_01572	3.43e-72	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HDLNMDOO_01573	7.37e-175	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HDLNMDOO_01574	1.26e-68	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
HDLNMDOO_01575	6.82e-235	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HDLNMDOO_01576	1.82e-134	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HDLNMDOO_01577	7.78e-159	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDLNMDOO_01578	8.18e-189	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HDLNMDOO_01579	3.94e-249	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HDLNMDOO_01580	1.93e-253	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HDLNMDOO_01581	1.77e-162	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HDLNMDOO_01582	4.34e-13	-	-	-	S	-	-	-	Bacteriophage holin
HDLNMDOO_01587	4.22e-31	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HDLNMDOO_01589	1.11e-155	rny	-	-	D	ko:K12088,ko:K18682	ko03018,ko05120,map03018,map05120	ko00000,ko00001,ko00002,ko01000,ko02044,ko03019	peptidase
HDLNMDOO_01590	1.06e-99	-	-	-	S	-	-	-	Phage tail protein
HDLNMDOO_01591	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HDLNMDOO_01593	7.39e-24	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
HDLNMDOO_01594	4.18e-99	-	-	-	S	-	-	-	Phage tail tube protein
HDLNMDOO_01595	5.71e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
HDLNMDOO_01596	1.11e-68	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HDLNMDOO_01597	4.14e-74	-	-	-	S	-	-	-	Phage head-tail joining protein
HDLNMDOO_01598	4.39e-29	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HDLNMDOO_01599	6.61e-247	-	-	-	S	-	-	-	Phage capsid family
HDLNMDOO_01600	4.68e-145	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HDLNMDOO_01601	3.28e-244	-	-	-	S	-	-	-	Phage portal protein
HDLNMDOO_01603	0.0	-	-	-	S	-	-	-	Phage Terminase
HDLNMDOO_01604	2.89e-105	-	-	-	L	-	-	-	Phage terminase, small subunit
HDLNMDOO_01605	1.71e-90	-	-	-	L	-	-	-	HNH nucleases
HDLNMDOO_01607	6.94e-45	-	-	-	-	-	-	-	-
HDLNMDOO_01608	1.79e-68	-	-	-	V	-	-	-	Abi-like protein
HDLNMDOO_01609	7.34e-42	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
HDLNMDOO_01614	5.81e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
HDLNMDOO_01616	6.62e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
HDLNMDOO_01618	4.21e-157	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
HDLNMDOO_01619	1.72e-30	-	-	-	L	-	-	-	Helix-turn-helix domain
HDLNMDOO_01620	2.7e-117	-	-	-	S	-	-	-	Putative HNHc nuclease
HDLNMDOO_01621	3.48e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
HDLNMDOO_01622	4.42e-96	-	-	-	S	-	-	-	AAA domain
HDLNMDOO_01624	1.67e-30	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
HDLNMDOO_01630	4.4e-102	-	-	-	S	-	-	-	DNA binding
HDLNMDOO_01631	1.44e-18	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDLNMDOO_01632	1.08e-21	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HDLNMDOO_01634	4.14e-23	-	-	-	-	-	-	-	-
HDLNMDOO_01637	3.23e-50	-	-	-	K	-	-	-	Peptidase S24-like
HDLNMDOO_01639	3.81e-86	-	-	-	S	-	-	-	AAA ATPase domain
HDLNMDOO_01640	9.66e-129	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	DNA methyltransferase
HDLNMDOO_01641	7e-117	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDLNMDOO_01643	3.18e-195	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HDLNMDOO_01644	3.59e-148	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HDLNMDOO_01645	5.1e-62	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HDLNMDOO_01646	5.51e-171	arcT	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
HDLNMDOO_01647	1.09e-114	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDLNMDOO_01648	5.45e-31	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HDLNMDOO_01649	2.66e-169	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HDLNMDOO_01650	4.87e-112	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HDLNMDOO_01651	4.02e-130	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HDLNMDOO_01652	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HDLNMDOO_01653	3.93e-163	-	-	-	-	-	-	-	-
HDLNMDOO_01654	1.67e-188	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HDLNMDOO_01655	1.49e-54	-	-	-	ET	-	-	-	Bacterial extracellular solute-binding proteins, family 3
HDLNMDOO_01656	2.39e-41	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLNMDOO_01657	2.58e-130	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HDLNMDOO_01658	6.86e-105	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HDLNMDOO_01659	1.13e-128	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HDLNMDOO_01660	1.15e-216	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HDLNMDOO_01661	2.75e-160	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDLNMDOO_01662	0.0	-	-	-	L	-	-	-	DNA helicase
HDLNMDOO_01664	1.78e-126	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDLNMDOO_01665	1.15e-60	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HDLNMDOO_01672	4.25e-58	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HDLNMDOO_01673	6.05e-75	-	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
HDLNMDOO_01674	5.38e-94	-	-	-	S	-	-	-	Domain of unknown function (DUF3841)
HDLNMDOO_01675	4.9e-288	-	-	-	S	-	-	-	Protein of unknown function DUF262
HDLNMDOO_01676	2.73e-204	spoVK	-	-	O	ko:K06413	-	ko00000	PFAM ATPase family associated with various cellular activities (AAA)
HDLNMDOO_01678	1.1e-84	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HDLNMDOO_01679	3.59e-92	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HDLNMDOO_01680	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HDLNMDOO_01681	2.11e-122	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDLNMDOO_01682	3.47e-75	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HDLNMDOO_01683	1e-221	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HDLNMDOO_01684	4.82e-20	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
HDLNMDOO_01685	1.77e-300	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HDLNMDOO_01686	1.38e-249	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HDLNMDOO_01687	3.63e-267	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HDLNMDOO_01688	3.66e-50	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HDLNMDOO_01689	5.38e-204	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDLNMDOO_01690	1.28e-76	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
HDLNMDOO_01691	1.14e-129	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HDLNMDOO_01693	4.3e-284	-	-	-	M	-	-	-	Rib/alpha-like repeat
HDLNMDOO_01694	2.15e-59	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HDLNMDOO_01695	2.3e-78	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HDLNMDOO_01696	1.17e-52	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDLNMDOO_01697	3.65e-74	napB	-	-	K	-	-	-	transcriptional
HDLNMDOO_01698	7.97e-90	mleR	-	-	K	-	-	-	LysR family
HDLNMDOO_01699	1.96e-312	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HDLNMDOO_01700	3.55e-161	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HDLNMDOO_01701	2.31e-81	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HDLNMDOO_01702	7.37e-77	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HDLNMDOO_01703	1.37e-96	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HDLNMDOO_01704	1.56e-254	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HDLNMDOO_01705	1.21e-45	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HDLNMDOO_01706	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HDLNMDOO_01707	5.56e-124	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HDLNMDOO_01708	1.79e-148	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HDLNMDOO_01709	1.3e-118	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HDLNMDOO_01710	1.72e-226	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HDLNMDOO_01712	1.96e-54	-	-	-	-	-	-	-	-
HDLNMDOO_01713	1.32e-41	-	-	-	K	-	-	-	GNAT family
HDLNMDOO_01714	2.28e-262	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HDLNMDOO_01715	1.46e-277	gdhA	1.4.1.3, 1.4.1.4	-	E	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	ko00000,ko00001,ko00002,ko01000,ko04147	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
HDLNMDOO_01716	5.43e-46	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HDLNMDOO_01717	1.54e-274	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HDLNMDOO_01718	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HDLNMDOO_01719	1.67e-209	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HDLNMDOO_01720	9.63e-158	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HDLNMDOO_01721	1.82e-243	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HDLNMDOO_01722	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HDLNMDOO_01723	1.14e-213	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HDLNMDOO_01724	7.99e-33	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HDLNMDOO_01725	3.09e-160	mocA	-	-	S	-	-	-	Oxidoreductase
HDLNMDOO_01726	1.39e-201	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HDLNMDOO_01729	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HDLNMDOO_01730	1.64e-126	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HDLNMDOO_01731	3.51e-270	-	-	-	G	ko:K16211	-	ko00000,ko02000	Transporter, major facilitator family protein
HDLNMDOO_01732	1.35e-95	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HDLNMDOO_01733	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HDLNMDOO_01734	9.38e-110	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HDLNMDOO_01735	0.0	-	-	-	E	-	-	-	Amino acid permease
HDLNMDOO_01736	1.22e-229	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
HDLNMDOO_01737	6.71e-214	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HDLNMDOO_01738	4.88e-90	-	-	-	K	-	-	-	Sugar-specific transcriptional regulator TrmB
HDLNMDOO_01739	1.31e-154	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HDLNMDOO_01740	9.8e-152	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
HDLNMDOO_01741	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HDLNMDOO_01742	5.64e-69	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HDLNMDOO_01743	2.04e-69	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HDLNMDOO_01744	3.03e-183	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HDLNMDOO_01745	5.63e-195	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HDLNMDOO_01746	2.24e-16	-	3.5.1.28	CBM50	M	ko:K22409	-	ko00000,ko01000	Lysin motif
HDLNMDOO_01747	8.07e-120	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HDLNMDOO_01748	2.75e-115	-	-	-	L	-	-	-	Probable transposase
HDLNMDOO_01749	2.42e-57	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDLNMDOO_01750	1.39e-174	-	-	-	V	-	-	-	MatE
HDLNMDOO_01751	6.88e-200	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HDLNMDOO_01752	1.99e-92	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HDLNMDOO_01753	2.28e-125	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HDLNMDOO_01754	2.26e-162	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HDLNMDOO_01755	3.21e-93	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HDLNMDOO_01756	2.76e-33	-	-	-	-	-	-	-	-
HDLNMDOO_01757	6.84e-232	yhdP	-	-	S	-	-	-	Transporter associated domain
HDLNMDOO_01758	1.01e-100	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HDLNMDOO_01759	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HDLNMDOO_01760	5.89e-316	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HDLNMDOO_01761	6.14e-269	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HDLNMDOO_01762	1e-68	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HDLNMDOO_01763	2.03e-16	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HDLNMDOO_01764	2.23e-123	-	-	-	-	-	-	-	-
HDLNMDOO_01765	3.89e-17	-	-	-	-	-	-	-	-
HDLNMDOO_01766	2.45e-132	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDLNMDOO_01767	8.41e-127	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDLNMDOO_01768	4.89e-111	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDLNMDOO_01769	1.88e-104	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDLNMDOO_01770	5.79e-240	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HDLNMDOO_01771	2.79e-14	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HDLNMDOO_01772	8.32e-188	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HDLNMDOO_01773	1.63e-68	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HDLNMDOO_01774	4.32e-100	-	-	-	K	-	-	-	rpiR family
HDLNMDOO_01775	2.99e-218	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HDLNMDOO_01776	3.24e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HDLNMDOO_01777	2.82e-140	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HDLNMDOO_01778	6.55e-130	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HDLNMDOO_01779	1.34e-52	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HDLNMDOO_01780	4.58e-183	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HDLNMDOO_01781	5.93e-60	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HDLNMDOO_01782	9.15e-72	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HDLNMDOO_01783	1.62e-149	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HDLNMDOO_01784	8.95e-95	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HDLNMDOO_01785	2.63e-32	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HDLNMDOO_01786	5.05e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HDLNMDOO_01787	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HDLNMDOO_01788	3.84e-62	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HDLNMDOO_01789	1.61e-119	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HDLNMDOO_01790	4.1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HDLNMDOO_01791	5.17e-86	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HDLNMDOO_01792	4.99e-113	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HDLNMDOO_01793	2.4e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HDLNMDOO_01794	2.08e-106	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HDLNMDOO_01795	1.65e-31	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HDLNMDOO_01796	1.13e-88	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HDLNMDOO_01797	4.28e-266	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HDLNMDOO_01798	8.94e-143	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HDLNMDOO_01799	7.16e-47	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HDLNMDOO_01800	1.72e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HDLNMDOO_01801	7.34e-74	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HDLNMDOO_01802	1.24e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HDLNMDOO_01803	1.93e-198	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDLNMDOO_01804	4.47e-71	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HDLNMDOO_01805	2.27e-127	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDLNMDOO_01806	8.76e-140	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDLNMDOO_01807	3.1e-138	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDLNMDOO_01808	6.22e-160	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HDLNMDOO_01809	1.04e-99	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HDLNMDOO_01810	2.29e-79	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HDLNMDOO_01812	2.82e-307	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HDLNMDOO_01813	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HDLNMDOO_01814	1.01e-79	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HDLNMDOO_01815	6.34e-111	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDLNMDOO_01816	1.24e-137	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HDLNMDOO_01817	2.1e-41	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
HDLNMDOO_01818	1.84e-110	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HDLNMDOO_01819	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HDLNMDOO_01820	2.6e-62	-	-	-	M	-	-	-	LysM domain protein
HDLNMDOO_01822	4.11e-142	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HDLNMDOO_01823	2.64e-128	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HDLNMDOO_01824	8.18e-73	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
HDLNMDOO_01825	1.43e-68	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HDLNMDOO_01826	1.17e-260	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HDLNMDOO_01827	5.16e-179	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDLNMDOO_01828	2.2e-110	-	-	-	S	-	-	-	(CBS) domain
HDLNMDOO_01829	4.72e-201	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HDLNMDOO_01830	1.45e-95	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HDLNMDOO_01831	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HDLNMDOO_01832	3.29e-173	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HDLNMDOO_01833	1.1e-42	yabO	-	-	J	-	-	-	S4 domain protein
HDLNMDOO_01834	2.11e-28	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HDLNMDOO_01835	1.23e-62	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HDLNMDOO_01836	1.62e-118	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HDLNMDOO_01837	2.49e-100	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HDLNMDOO_01838	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HDLNMDOO_01839	6.53e-167	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HDLNMDOO_01840	2.4e-214	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDLNMDOO_01841	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HDLNMDOO_01842	2.05e-40	-	-	-	-	-	-	-	-
HDLNMDOO_01843	5.35e-113	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HDLNMDOO_01844	3.5e-18	-	-	-	-	-	-	-	-
HDLNMDOO_01845	6.8e-185	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDLNMDOO_01846	4.44e-85	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
HDLNMDOO_01847	1.16e-309	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
HDLNMDOO_01848	7.2e-106	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
HDLNMDOO_01849	2.88e-17	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
HDLNMDOO_01850	2.92e-264	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HDLNMDOO_01852	3.61e-79	uspA3	-	-	T	-	-	-	universal stress protein
HDLNMDOO_01854	1.06e-20	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
HDLNMDOO_01855	5.96e-263	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HDLNMDOO_01856	2.88e-231	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HDLNMDOO_01857	2.39e-192	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HDLNMDOO_01858	2.19e-91	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HDLNMDOO_01859	1.41e-287	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HDLNMDOO_01860	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HDLNMDOO_01861	4.38e-256	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HDLNMDOO_01862	1.84e-203	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HDLNMDOO_01863	2.09e-111	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HDLNMDOO_01864	7.25e-85	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HDLNMDOO_01865	5.2e-116	ymfI	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HDLNMDOO_01866	1.61e-183	ymfH	-	-	S	-	-	-	Peptidase M16
HDLNMDOO_01867	1.2e-135	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HDLNMDOO_01868	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HDLNMDOO_01869	2.62e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HDLNMDOO_01870	2.88e-124	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HDLNMDOO_01871	8.29e-83	-	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
HDLNMDOO_01872	1.61e-207	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HDLNMDOO_01873	7e-250	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HDLNMDOO_01874	8.5e-24	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HDLNMDOO_01875	6.2e-163	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HDLNMDOO_01876	1.59e-38	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HDLNMDOO_01877	1.82e-283	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HDLNMDOO_01878	4.54e-87	ybbR	-	-	S	-	-	-	YbbR-like protein
HDLNMDOO_01879	1.95e-162	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HDLNMDOO_01880	3.2e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
HDLNMDOO_01881	4.26e-146	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HDLNMDOO_01882	4.75e-90	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HDLNMDOO_01883	1e-72	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HDLNMDOO_01884	7.01e-181	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HDLNMDOO_01885	1.52e-134	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HDLNMDOO_01886	1.68e-148	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HDLNMDOO_01887	7.86e-53	-	-	-	-	-	-	-	-
HDLNMDOO_01888	4.3e-91	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HDLNMDOO_01889	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HDLNMDOO_01890	1.19e-32	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HDLNMDOO_01891	6.32e-224	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HDLNMDOO_01892	5.39e-189	-	-	-	E	-	-	-	Major Facilitator Superfamily
HDLNMDOO_01893	8.04e-212	yclK	-	-	T	-	-	-	Histidine kinase
HDLNMDOO_01894	1.13e-133	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HDLNMDOO_01895	5.56e-151	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDLNMDOO_01896	4.33e-298	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDLNMDOO_01897	9.95e-165	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HDLNMDOO_01898	1.99e-264	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HDLNMDOO_01899	4.83e-231	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HDLNMDOO_01900	1.59e-174	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HDLNMDOO_01902	2.07e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HDLNMDOO_01903	5.86e-191	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HDLNMDOO_01904	9.11e-195	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HDLNMDOO_01905	7.15e-161	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HDLNMDOO_01906	4.6e-101	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
HDLNMDOO_01907	1.23e-107	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HDLNMDOO_01908	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HDLNMDOO_01909	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HDLNMDOO_01910	2.34e-234	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HDLNMDOO_01911	2.85e-247	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HDLNMDOO_01912	1.82e-148	-	-	-	M	-	-	-	Core-2/I-Branching enzyme
HDLNMDOO_01913	5.65e-114	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
HDLNMDOO_01914	1.11e-162	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HDLNMDOO_01915	1.15e-139	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HDLNMDOO_01916	9.02e-117	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HDLNMDOO_01917	1.35e-91	epsB	-	-	M	-	-	-	biosynthesis protein
HDLNMDOO_01919	7.76e-140	cps2J	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HDLNMDOO_01920	5.72e-83	-	-	-	S	ko:K16710	-	ko00000	Polysaccharide pyruvyl transferase
HDLNMDOO_01922	1.7e-26	-	-	-	H	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
HDLNMDOO_01923	7.59e-114	-	-	-	-	-	-	-	-
HDLNMDOO_01924	5.72e-50	-	-	-	M	-	-	-	group 2 family protein
HDLNMDOO_01925	7.41e-114	-	-	-	M	-	-	-	Glycosyl transferase family 8
HDLNMDOO_01926	3.9e-138	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD/REP helicase N-terminal domain
HDLNMDOO_01927	4.12e-173	-	-	-	L	-	-	-	AAA ATPase domain
HDLNMDOO_01928	6.57e-108	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HDLNMDOO_01930	7.12e-147	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
HDLNMDOO_01931	5.97e-166	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HDLNMDOO_01932	4.52e-239	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HDLNMDOO_01933	2.26e-130	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HDLNMDOO_01934	5.46e-181	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HDLNMDOO_01935	3.23e-77	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HDLNMDOO_01936	1.64e-147	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HDLNMDOO_01937	1.67e-45	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDLNMDOO_01938	4.33e-113	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HDLNMDOO_01939	1.69e-80	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HDLNMDOO_01940	7.81e-193	-	-	-	EGP	-	-	-	Major Facilitator
HDLNMDOO_01942	3.12e-87	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HDLNMDOO_01943	8.26e-36	adhR	-	-	K	-	-	-	transcriptional regulator
HDLNMDOO_01944	1.88e-114	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HDLNMDOO_01945	1.35e-127	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HDLNMDOO_01946	9.84e-72	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HDLNMDOO_01947	4.93e-138	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HDLNMDOO_01948	1.6e-126	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HDLNMDOO_01949	1.47e-131	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HDLNMDOO_01950	5.51e-50	-	-	-	-	-	-	-	-
HDLNMDOO_01951	1.87e-69	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HDLNMDOO_01952	4.28e-115	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HDLNMDOO_01953	3.13e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HDLNMDOO_01954	2.94e-242	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HDLNMDOO_01955	3.11e-33	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HDLNMDOO_01956	1.02e-138	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HDLNMDOO_01957	2.02e-152	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HDLNMDOO_01958	8.74e-104	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HDLNMDOO_01959	7.29e-130	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HDLNMDOO_01960	1.17e-161	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HDLNMDOO_01961	2.13e-91	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HDLNMDOO_01962	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HDLNMDOO_01963	1.36e-78	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
HDLNMDOO_01964	2.46e-93	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HDLNMDOO_01966	5.09e-83	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HDLNMDOO_01967	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HDLNMDOO_01968	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HDLNMDOO_01969	1.75e-45	-	-	-	-	-	-	-	-
HDLNMDOO_01970	3.93e-180	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDLNMDOO_01971	1.42e-197	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HDLNMDOO_01972	1.57e-123	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HDLNMDOO_01973	2.83e-199	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase