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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HALMKLNM_00003	5.21e-226	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HALMKLNM_00004	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HALMKLNM_00005	8.03e-246	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HALMKLNM_00006	1.08e-240	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HALMKLNM_00007	6.66e-76	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HALMKLNM_00008	4.45e-104	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HALMKLNM_00009	3.58e-241	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HALMKLNM_00010	5.2e-225	-	-	-	S	-	-	-	Protein of unknown function DUF262
HALMKLNM_00012	1.26e-48	-	-	-	-	-	-	-	-
HALMKLNM_00013	9.26e-87	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HALMKLNM_00014	1.29e-79	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HALMKLNM_00015	6.05e-129	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HALMKLNM_00016	1.48e-36	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HALMKLNM_00017	6.94e-130	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HALMKLNM_00018	6.31e-125	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HALMKLNM_00019	4.97e-248	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HALMKLNM_00020	4.05e-61	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HALMKLNM_00021	4.61e-84	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HALMKLNM_00022	2.06e-274	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HALMKLNM_00023	3.3e-160	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HALMKLNM_00024	4.27e-130	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HALMKLNM_00025	7.35e-140	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HALMKLNM_00026	6.3e-290	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HALMKLNM_00027	2.1e-305	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HALMKLNM_00028	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HALMKLNM_00029	1.05e-152	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
HALMKLNM_00030	3.09e-59	ykuL	-	-	S	-	-	-	CBS domain
HALMKLNM_00031	3.44e-92	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HALMKLNM_00032	4.06e-224	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HALMKLNM_00033	3.24e-115	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HALMKLNM_00035	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HALMKLNM_00036	2.92e-28	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HALMKLNM_00037	6.56e-163	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HALMKLNM_00038	1.22e-144	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HALMKLNM_00040	3.15e-69	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HALMKLNM_00041	1.16e-121	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HALMKLNM_00042	1e-85	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HALMKLNM_00043	1.38e-124	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HALMKLNM_00044	8.2e-131	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HALMKLNM_00046	2.95e-59	ytpP	-	-	CO	-	-	-	Thioredoxin
HALMKLNM_00047	2.48e-97	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HALMKLNM_00048	5.61e-297	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HALMKLNM_00049	1.76e-282	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HALMKLNM_00050	6.4e-80	phaJ	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
HALMKLNM_00051	1.25e-87	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HALMKLNM_00052	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HALMKLNM_00053	5.99e-137	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HALMKLNM_00054	5.32e-63	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HALMKLNM_00055	1.04e-85	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HALMKLNM_00056	2.46e-95	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HALMKLNM_00057	3.28e-136	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HALMKLNM_00058	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HALMKLNM_00059	1.25e-102	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HALMKLNM_00060	4.44e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HALMKLNM_00061	5.01e-69	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HALMKLNM_00062	2.34e-91	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HALMKLNM_00063	2.94e-229	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HALMKLNM_00064	1.36e-40	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HALMKLNM_00065	1.43e-98	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HALMKLNM_00066	3.44e-91	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HALMKLNM_00067	2.79e-65	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HALMKLNM_00068	2.64e-103	-	-	-	H	-	-	-	Nodulation protein S (NodS)
HALMKLNM_00069	3.25e-153	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HALMKLNM_00070	1.58e-73	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HALMKLNM_00071	8.93e-35	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HALMKLNM_00072	5.76e-113	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HALMKLNM_00073	1.39e-119	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HALMKLNM_00074	9.8e-37	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HALMKLNM_00075	4.91e-172	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HALMKLNM_00076	7.31e-164	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HALMKLNM_00077	1.82e-49	-	-	-	-	-	-	-	-
HALMKLNM_00078	4.68e-119	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HALMKLNM_00079	9.37e-76	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HALMKLNM_00080	1.81e-199	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HALMKLNM_00081	3.59e-285	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HALMKLNM_00082	2.85e-138	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HALMKLNM_00084	1.46e-141	csrR	-	-	K	-	-	-	response regulator
HALMKLNM_00085	1.54e-218	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HALMKLNM_00086	1.19e-151	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HALMKLNM_00087	5.31e-23	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HALMKLNM_00088	1.36e-169	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HALMKLNM_00089	1.22e-142	-	-	-	-	-	-	-	-
HALMKLNM_00090	1.14e-147	-	-	-	-	-	-	-	-
HALMKLNM_00091	1.45e-48	-	-	-	S	-	-	-	Protein conserved in bacteria
HALMKLNM_00092	3.77e-123	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HALMKLNM_00093	1.4e-60	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HALMKLNM_00094	1.45e-46	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HALMKLNM_00095	3.85e-132	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HALMKLNM_00096	3.49e-183	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HALMKLNM_00097	1.44e-23	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HALMKLNM_00098	4.39e-104	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HALMKLNM_00099	3.13e-154	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HALMKLNM_00100	5.91e-65	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HALMKLNM_00101	3.69e-227	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HALMKLNM_00102	1.29e-106	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HALMKLNM_00103	7.41e-41	ynzC	-	-	S	-	-	-	UPF0291 protein
HALMKLNM_00104	1.62e-35	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
HALMKLNM_00105	3.24e-118	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HALMKLNM_00106	2.16e-58	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HALMKLNM_00107	2.76e-87	yciQ	-	-	P	-	-	-	membrane protein (DUF2207)
HALMKLNM_00109	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HALMKLNM_00110	5.52e-51	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HALMKLNM_00111	1.29e-89	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HALMKLNM_00112	2.47e-34	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HALMKLNM_00113	8.22e-203	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HALMKLNM_00114	3.96e-58	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HALMKLNM_00115	6.17e-24	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HALMKLNM_00116	6.09e-141	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HALMKLNM_00117	1.56e-257	ynbB	-	-	P	-	-	-	aluminum resistance
HALMKLNM_00118	1.3e-59	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HALMKLNM_00119	4.66e-312	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HALMKLNM_00121	6.13e-47	-	2.1.1.63	-	H	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HALMKLNM_00122	8.28e-64	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HALMKLNM_00123	1.02e-147	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HALMKLNM_00124	4.78e-104	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HALMKLNM_00125	2.86e-134	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HALMKLNM_00126	6.42e-131	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HALMKLNM_00127	3.58e-196	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HALMKLNM_00128	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HALMKLNM_00129	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HALMKLNM_00130	1.16e-85	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HALMKLNM_00131	1.25e-216	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HALMKLNM_00132	3.32e-53	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HALMKLNM_00133	4.38e-35	ylxQ	-	-	J	-	-	-	ribosomal protein
HALMKLNM_00134	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HALMKLNM_00135	6.33e-74	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HALMKLNM_00136	2.86e-152	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HALMKLNM_00137	5.22e-120	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HALMKLNM_00138	4.33e-165	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HALMKLNM_00139	3.65e-75	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HALMKLNM_00140	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HALMKLNM_00141	8.15e-218	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HALMKLNM_00142	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HALMKLNM_00144	1.74e-257	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HALMKLNM_00145	1.83e-153	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HALMKLNM_00146	1.83e-41	-	-	-	-	-	-	-	-
HALMKLNM_00147	4.38e-140	ampC	-	-	V	-	-	-	Beta-lactamase
HALMKLNM_00148	3.26e-141	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HALMKLNM_00149	1.21e-276	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HALMKLNM_00150	1.19e-111	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HALMKLNM_00151	1.04e-230	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HALMKLNM_00152	7.51e-114	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HALMKLNM_00153	1.9e-171	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HALMKLNM_00154	2.18e-129	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HALMKLNM_00155	2.33e-124	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HALMKLNM_00156	7.74e-34	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HALMKLNM_00157	4.19e-57	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HALMKLNM_00158	1.62e-73	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HALMKLNM_00159	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HALMKLNM_00160	3.29e-181	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HALMKLNM_00161	1.33e-311	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HALMKLNM_00162	6.22e-70	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HALMKLNM_00163	8.32e-21	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HALMKLNM_00164	1.78e-261	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HALMKLNM_00165	2.82e-214	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HALMKLNM_00166	1.77e-35	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HALMKLNM_00167	6.63e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HALMKLNM_00168	2.21e-236	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HALMKLNM_00169	9.86e-36	spxA	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HALMKLNM_00170	1.78e-118	-	-	-	M	-	-	-	Phosphotransferase enzyme family
HALMKLNM_00171	8.34e-132	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HALMKLNM_00172	8.22e-30	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HALMKLNM_00173	1.76e-151	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HALMKLNM_00174	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HALMKLNM_00175	3.13e-177	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HALMKLNM_00176	2.51e-192	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HALMKLNM_00177	1.11e-115	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HALMKLNM_00178	1.98e-238	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HALMKLNM_00179	1.38e-145	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HALMKLNM_00180	4.31e-73	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HALMKLNM_00181	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HALMKLNM_00182	7.35e-69	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HALMKLNM_00183	1.72e-302	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HALMKLNM_00184	3.84e-306	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HALMKLNM_00185	2.67e-181	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HALMKLNM_00186	9.72e-35	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HALMKLNM_00187	4.17e-129	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HALMKLNM_00188	7.36e-294	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HALMKLNM_00189	4.55e-187	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HALMKLNM_00190	6.15e-53	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HALMKLNM_00191	9.04e-263	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HALMKLNM_00192	1.32e-55	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HALMKLNM_00193	1.99e-37	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HALMKLNM_00194	1.6e-74	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HALMKLNM_00195	2.74e-145	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HALMKLNM_00196	2.19e-78	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HALMKLNM_00197	2.16e-251	-	-	-	E	ko:K03294	-	ko00000	amino acid
HALMKLNM_00198	2.49e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HALMKLNM_00199	1.33e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HALMKLNM_00200	2.6e-53	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HALMKLNM_00201	2.18e-146	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HALMKLNM_00202	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HALMKLNM_00203	3.51e-05	-	-	-	S	-	-	-	Tetratricopeptide repeat
HALMKLNM_00204	6.83e-274	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HALMKLNM_00205	6.79e-246	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HALMKLNM_00206	3.67e-251	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HALMKLNM_00207	3.69e-313	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HALMKLNM_00208	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HALMKLNM_00209	1.47e-30	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HALMKLNM_00210	3.51e-33	-	-	-	-	-	-	-	-
HALMKLNM_00211	7.87e-111	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HALMKLNM_00212	4.82e-21	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily
HALMKLNM_00213	3.57e-33	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HALMKLNM_00214	6.09e-96	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HALMKLNM_00215	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HALMKLNM_00216	3.81e-188	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HALMKLNM_00217	7.81e-147	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HALMKLNM_00218	9.75e-188	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HALMKLNM_00219	8.72e-126	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HALMKLNM_00220	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HALMKLNM_00221	2.86e-24	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HALMKLNM_00222	5.02e-94	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HALMKLNM_00223	3.35e-65	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HALMKLNM_00224	7.34e-167	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HALMKLNM_00225	8.62e-123	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HALMKLNM_00226	9.14e-41	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HALMKLNM_00227	1.37e-131	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HALMKLNM_00228	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HALMKLNM_00229	3.04e-283	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HALMKLNM_00230	9.88e-175	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HALMKLNM_00231	6.95e-96	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HALMKLNM_00232	8.15e-293	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HALMKLNM_00233	1.19e-203	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HALMKLNM_00234	5.56e-138	-	-	-	S	-	-	-	Acyltransferase family
HALMKLNM_00235	1.38e-242	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HALMKLNM_00236	1.82e-156	-	-	-	K	-	-	-	LysR substrate binding domain
HALMKLNM_00238	1.4e-27	-	-	-	-	-	-	-	-
HALMKLNM_00239	1.61e-73	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HALMKLNM_00240	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HALMKLNM_00241	1.68e-61	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HALMKLNM_00242	1.71e-90	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HALMKLNM_00243	1.24e-186	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HALMKLNM_00244	8.38e-133	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HALMKLNM_00245	8.17e-143	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HALMKLNM_00246	6.58e-172	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HALMKLNM_00247	2.94e-155	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HALMKLNM_00248	5.19e-119	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HALMKLNM_00249	1.57e-271	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HALMKLNM_00250	1.79e-44	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HALMKLNM_00251	1.22e-178	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HALMKLNM_00252	4.9e-300	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HALMKLNM_00253	5.12e-72	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HALMKLNM_00254	2.09e-106	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HALMKLNM_00255	6.01e-100	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HALMKLNM_00256	4.35e-160	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HALMKLNM_00257	6.79e-116	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HALMKLNM_00258	1.72e-110	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HALMKLNM_00259	1.25e-125	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HALMKLNM_00262	2.08e-148	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HALMKLNM_00263	5.93e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HALMKLNM_00264	1.87e-75	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HALMKLNM_00266	1.91e-87	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HALMKLNM_00267	2.69e-142	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HALMKLNM_00268	5.3e-136	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HALMKLNM_00269	3.57e-168	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HALMKLNM_00270	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HALMKLNM_00271	4.75e-201	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HALMKLNM_00272	6.15e-73	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HALMKLNM_00273	8.08e-168	-	-	-	C	-	-	-	Aldo keto reductase
HALMKLNM_00275	3.71e-142	ydhF	-	-	S	-	-	-	Aldo keto reductase
HALMKLNM_00277	2.64e-100	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HALMKLNM_00278	3.97e-69	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HALMKLNM_00279	1.77e-33	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HALMKLNM_00280	1.79e-170	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HALMKLNM_00281	1.67e-123	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HALMKLNM_00282	2.09e-108	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HALMKLNM_00283	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HALMKLNM_00284	2.46e-265	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HALMKLNM_00285	2.33e-257	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
HALMKLNM_00286	1.54e-36	cas6	-	-	S	-	-	-	CRISPR-associated endoribonuclease Cas6
HALMKLNM_00287	4.12e-250	csm1	-	-	S	ko:K07016	-	ko00000,ko02048	CRISPR-associated protein Csm1 family
HALMKLNM_00288	8.49e-37	-	-	-	L	ko:K19138	-	ko00000,ko02048	Pfam:DUF310
HALMKLNM_00289	3.82e-88	csm3	-	-	L	ko:K09002	-	ko00000,ko02048	RAMP superfamily
HALMKLNM_00290	2.22e-80	-	-	-	L	ko:K19139	-	ko00000,ko02048	CRISPR-associated RAMP protein, Csm4 family
HALMKLNM_00291	3.21e-85	csm5	-	-	L	ko:K19140	-	ko00000,ko02048	RAMP superfamily
HALMKLNM_00292	5.47e-110	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HALMKLNM_00293	1.48e-41	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HALMKLNM_00294	1.44e-87	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HALMKLNM_00295	2.93e-129	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
HALMKLNM_00296	1.19e-53	-	-	-	S	-	-	-	repeat protein
HALMKLNM_00297	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HALMKLNM_00299	8.63e-20	-	-	-	-	-	-	-	-
HALMKLNM_00302	2.32e-109	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HALMKLNM_00303	2.77e-88	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HALMKLNM_00304	1.97e-56	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HALMKLNM_00305	7.45e-220	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HALMKLNM_00306	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HALMKLNM_00307	1.15e-163	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HALMKLNM_00308	4.31e-127	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HALMKLNM_00309	2e-88	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HALMKLNM_00310	5.6e-17	-	-	-	-	-	-	-	-
HALMKLNM_00311	1.24e-183	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HALMKLNM_00312	8.52e-55	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
HALMKLNM_00313	5.35e-150	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HALMKLNM_00314	7.53e-98	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HALMKLNM_00315	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HALMKLNM_00316	7.24e-71	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HALMKLNM_00317	3.62e-72	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
HALMKLNM_00318	9.43e-57	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HALMKLNM_00319	1.69e-164	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HALMKLNM_00320	8.7e-98	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HALMKLNM_00321	1.07e-256	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HALMKLNM_00322	1.29e-141	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HALMKLNM_00323	1.2e-236	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HALMKLNM_00324	1.06e-109	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HALMKLNM_00325	5.8e-112	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HALMKLNM_00326	3.29e-173	-	-	-	K	-	-	-	Transcriptional regulator
HALMKLNM_00327	7.65e-185	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HALMKLNM_00328	4.04e-148	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HALMKLNM_00329	4.06e-218	araT1	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HALMKLNM_00330	3.49e-111	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HALMKLNM_00332	3.6e-57	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HALMKLNM_00333	6.61e-219	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HALMKLNM_00334	3.11e-48	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HALMKLNM_00335	5.89e-34	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
HALMKLNM_00336	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HALMKLNM_00337	2.15e-51	-	-	-	-	-	-	-	-
HALMKLNM_00340	9.6e-184	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HALMKLNM_00341	1.96e-97	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HALMKLNM_00342	6.65e-131	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HALMKLNM_00343	1.76e-232	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HALMKLNM_00344	5.93e-90	-	-	-	L	-	-	-	DNA alkylation repair enzyme
HALMKLNM_00345	2.44e-174	-	-	-	EG	-	-	-	EamA-like transporter family
HALMKLNM_00346	3.9e-190	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HALMKLNM_00347	4.46e-256	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HALMKLNM_00348	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HALMKLNM_00349	1.24e-173	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HALMKLNM_00350	1.56e-219	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HALMKLNM_00351	6.9e-163	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HALMKLNM_00352	1.47e-105	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HALMKLNM_00354	5.96e-118	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HALMKLNM_00355	4.72e-201	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HALMKLNM_00356	5.49e-54	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HALMKLNM_00357	5.64e-256	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HALMKLNM_00358	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HALMKLNM_00359	6.47e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HALMKLNM_00360	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HALMKLNM_00361	1.7e-211	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HALMKLNM_00362	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HALMKLNM_00364	6.49e-53	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HALMKLNM_00365	2.28e-105	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HALMKLNM_00366	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HALMKLNM_00367	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HALMKLNM_00368	1.79e-251	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HALMKLNM_00369	2.07e-52	-	-	-	K	-	-	-	Transcriptional regulator
HALMKLNM_00370	4.15e-148	-	-	-	S	-	-	-	EDD domain protein, DegV family
HALMKLNM_00371	6.76e-92	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase, peptidase S26
HALMKLNM_00372	1.51e-52	-	6.3.3.2	-	I	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Protein conserved in bacteria
HALMKLNM_00373	1.07e-235	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HALMKLNM_00374	4.16e-83	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HALMKLNM_00375	9.75e-120	-	-	-	EG	-	-	-	EamA-like transporter family
HALMKLNM_00376	1.07e-103	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type Na efflux pump, permease component
HALMKLNM_00377	9.85e-142	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	Domain of unknown function (DUF4162)
HALMKLNM_00378	2.83e-26	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HALMKLNM_00380	2.02e-48	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HALMKLNM_00381	3.35e-288	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HALMKLNM_00382	3.19e-220	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HALMKLNM_00383	1e-77	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphatase family
HALMKLNM_00384	3.32e-191	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HALMKLNM_00385	4.73e-40	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HALMKLNM_00386	5.28e-220	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HALMKLNM_00387	2.93e-274	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HALMKLNM_00389	3.85e-114	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HALMKLNM_00390	4.63e-199	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HALMKLNM_00391	5.92e-40	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HALMKLNM_00392	2.42e-88	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HALMKLNM_00393	6.89e-195	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HALMKLNM_00394	4.22e-106	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
HALMKLNM_00395	1.02e-111	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HALMKLNM_00396	1.12e-15	-	-	-	M	-	-	-	Lysin motif
HALMKLNM_00397	8.55e-154	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HALMKLNM_00398	1.2e-78	-	-	-	S	-	-	-	Helix-turn-helix domain
HALMKLNM_00399	2.54e-276	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HALMKLNM_00400	1.39e-58	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HALMKLNM_00401	2.97e-149	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HALMKLNM_00402	5.36e-51	-	-	-	-	-	-	-	-
HALMKLNM_00403	7.94e-110	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HALMKLNM_00406	7.63e-237	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HALMKLNM_00407	4.42e-264	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HALMKLNM_00408	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HALMKLNM_00409	4.75e-215	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HALMKLNM_00410	3.77e-135	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HALMKLNM_00411	4.22e-87	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HALMKLNM_00412	7.91e-102	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HALMKLNM_00413	5.43e-166	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HALMKLNM_00414	1.85e-111	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain protein
HALMKLNM_00415	2.93e-260	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HALMKLNM_00416	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HALMKLNM_00418	1.14e-101	-	-	-	F	-	-	-	Hydrolase, nudix family
HALMKLNM_00419	6.25e-72	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HALMKLNM_00420	1.64e-87	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HALMKLNM_00421	9.98e-05	-	-	-	J	-	-	-	GNAT acetyltransferase
HALMKLNM_00422	2.78e-71	-	-	-	M	-	-	-	GNAT acetyltransferase
HALMKLNM_00424	1.45e-241	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HALMKLNM_00425	5.59e-84	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HALMKLNM_00426	1.77e-235	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HALMKLNM_00427	1.17e-98	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HALMKLNM_00428	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HALMKLNM_00429	1.39e-142	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HALMKLNM_00430	3.06e-159	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HALMKLNM_00431	1.64e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF441)
HALMKLNM_00432	8.84e-76	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HALMKLNM_00433	2.3e-127	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HALMKLNM_00434	2.7e-79	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HALMKLNM_00435	2.42e-76	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HALMKLNM_00436	6.85e-49	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HALMKLNM_00437	6.25e-72	-	-	-	-	-	-	-	-
HALMKLNM_00438	4.92e-11	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HALMKLNM_00439	5.36e-07	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HALMKLNM_00440	2.69e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HALMKLNM_00441	0.000912	-	2.7.11.1	-	T	ko:K12132	-	ko00000,ko01000,ko01001	NACHT domain
HALMKLNM_00442	1.73e-274	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HALMKLNM_00443	4.03e-102	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HALMKLNM_00444	2.56e-155	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HALMKLNM_00445	1.28e-224	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HALMKLNM_00446	1.94e-124	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HALMKLNM_00447	5.99e-91	-	-	-	-	-	-	-	-
HALMKLNM_00449	1.47e-37	-	-	-	S	-	-	-	Cysteine-rich CPCC
HALMKLNM_00451	2e-09	-	-	-	M	-	-	-	LysM domain
HALMKLNM_00452	4.7e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HALMKLNM_00453	1.55e-37	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HALMKLNM_00454	3.02e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HALMKLNM_00461	4.18e-52	-	-	-	H	-	-	-	Methyltransferase domain
HALMKLNM_00462	6.84e-55	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HALMKLNM_00463	2.76e-52	-	-	-	M	-	-	-	Acetyltransferase (GNAT) family
HALMKLNM_00465	1.62e-29	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
HALMKLNM_00466	2.29e-51	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HALMKLNM_00468	2.66e-106	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HALMKLNM_00469	1.8e-40	-	-	-	S	-	-	-	CHY zinc finger
HALMKLNM_00470	2.08e-52	ywnA	-	-	K	-	-	-	Transcriptional regulator
HALMKLNM_00471	8.23e-105	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HALMKLNM_00474	7.16e-154	-	-	-	M	-	-	-	Glycosyl transferases group 1
HALMKLNM_00475	1.81e-78	-	-	-	M	-	-	-	Glycosyl transferases group 1
HALMKLNM_00476	3.52e-225	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HALMKLNM_00477	2.65e-184	-	5.1.3.6	-	GM	ko:K08679	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	RmlD substrate binding domain
HALMKLNM_00478	3.37e-124	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HALMKLNM_00479	2.2e-32	-	-	-	M	-	-	-	Glycosyl transferase
HALMKLNM_00480	2.54e-12	-	-	-	M	-	-	-	Glycosyl transferases group 1
HALMKLNM_00481	1.42e-146	-	-	-	S	-	-	-	Glycosyltransferase WbsX
HALMKLNM_00482	3.45e-51	-	-	-	-	-	-	-	-
HALMKLNM_00485	3.65e-70	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HALMKLNM_00486	1.86e-45	rfbF	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
HALMKLNM_00487	1.84e-88	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HALMKLNM_00488	4.2e-92	-	-	-	M	-	-	-	glycosyl transferase group 1
HALMKLNM_00489	9.03e-97	-	-	-	M	-	-	-	glycosyl transferase group 1
HALMKLNM_00490	1.24e-49	-	-	GT4	M	ko:K13004	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase 4-like
HALMKLNM_00491	2.17e-99	-	-	-	M	-	-	-	Glycosyl transferases group 1
HALMKLNM_00492	8.13e-52	-	-	-	S	ko:K13006,ko:K19429	-	ko00000,ko01000,ko01005	Bacterial transferase hexapeptide (six repeats)
HALMKLNM_00493	2.94e-98	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
HALMKLNM_00494	4.31e-210	epsN	-	-	M	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
HALMKLNM_00495	7.06e-85	-	-	-	GM	-	-	-	CoA-binding domain
HALMKLNM_00496	1.23e-96	capD	-	-	GM	-	-	-	CoA-binding domain
HALMKLNM_00497	4.38e-81	-	-	-	D	-	-	-	AAA domain
HALMKLNM_00498	4.45e-59	-	-	-	M	-	-	-	Chain length determinant protein
HALMKLNM_00499	2.35e-52	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HALMKLNM_00500	9.71e-225	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HALMKLNM_00501	3.87e-82	-	-	-	-	-	-	-	-
HALMKLNM_00502	4.55e-105	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HALMKLNM_00503	3.53e-144	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HALMKLNM_00504	9.13e-77	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HALMKLNM_00505	1.33e-238	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HALMKLNM_00506	5.92e-33	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HALMKLNM_00507	1.12e-266	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HALMKLNM_00509	8.38e-80	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HALMKLNM_00510	7.81e-69	-	-	-	S	-	-	-	Membrane
HALMKLNM_00511	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HALMKLNM_00512	1.05e-76	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HALMKLNM_00513	5.33e-230	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HALMKLNM_00514	5.12e-32	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HALMKLNM_00515	8.4e-66	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HALMKLNM_00516	2.78e-116	tnp2	-	-	L	-	-	-	Transposase
HALMKLNM_00517	6.61e-36	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HALMKLNM_00518	4.61e-153	-	-	-	T	-	-	-	diguanylate cyclase activity
HALMKLNM_00519	0.0	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HALMKLNM_00520	4.22e-223	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HALMKLNM_00521	2.99e-256	-	-	-	S	-	-	-	Protein conserved in bacteria
HALMKLNM_00522	1.54e-236	-	-	-	-	-	-	-	-
HALMKLNM_00523	2.76e-163	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HALMKLNM_00524	1.87e-48	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
HALMKLNM_00525	1.84e-183	pbuO_1	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HALMKLNM_00526	5.09e-196	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HALMKLNM_00527	7e-134	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HALMKLNM_00528	3.23e-121	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HALMKLNM_00529	4.26e-277	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
HALMKLNM_00530	7.71e-254	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HALMKLNM_00531	5.29e-178	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HALMKLNM_00532	4.3e-243	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HALMKLNM_00533	1.34e-202	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HALMKLNM_00534	4.09e-52	-	-	-	M	-	-	-	LysM domain
HALMKLNM_00535	5.6e-25	-	-	-	P	-	-	-	Rhodanese Homology Domain
HALMKLNM_00536	1.22e-66	-	-	-	M	-	-	-	LysM domain protein
HALMKLNM_00537	1.37e-116	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HALMKLNM_00538	5.22e-109	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HALMKLNM_00540	2e-91	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HALMKLNM_00541	3.7e-130	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HALMKLNM_00542	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HALMKLNM_00543	3.98e-92	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HALMKLNM_00544	1.4e-104	ylmH	-	-	S	-	-	-	S4 domain protein
HALMKLNM_00545	8.19e-27	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HALMKLNM_00546	8.14e-43	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HALMKLNM_00547	1.5e-227	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HALMKLNM_00548	6.07e-240	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HALMKLNM_00549	2.27e-76	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HALMKLNM_00550	8.63e-195	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HALMKLNM_00551	2.09e-233	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HALMKLNM_00552	1.21e-170	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HALMKLNM_00553	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HALMKLNM_00554	1.05e-13	ftsL	-	-	D	-	-	-	Essential cell division protein
HALMKLNM_00555	1.28e-180	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HALMKLNM_00556	2.65e-82	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HALMKLNM_00558	5.43e-196	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HALMKLNM_00559	1.16e-05	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HALMKLNM_00560	1.59e-124	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HALMKLNM_00561	6.52e-138	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HALMKLNM_00562	8.17e-115	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HALMKLNM_00563	3.02e-122	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HALMKLNM_00564	1.13e-162	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HALMKLNM_00565	8.33e-97	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HALMKLNM_00566	1.33e-70	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HALMKLNM_00567	6.08e-138	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HALMKLNM_00568	2.35e-207	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HALMKLNM_00569	1.96e-29	-	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
HALMKLNM_00570	2.27e-102	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HALMKLNM_00571	6.92e-169	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HALMKLNM_00572	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HALMKLNM_00573	2.9e-248	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HALMKLNM_00574	3.39e-203	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HALMKLNM_00575	2.64e-222	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HALMKLNM_00576	3.66e-72	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HALMKLNM_00577	5.9e-130	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HALMKLNM_00578	5.85e-31	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HALMKLNM_00579	1.1e-245	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HALMKLNM_00581	6.35e-97	uspA	-	-	T	-	-	-	universal stress protein
HALMKLNM_00582	2.81e-68	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HALMKLNM_00583	4.24e-252	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HALMKLNM_00584	3.96e-156	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HALMKLNM_00587	2.07e-58	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HALMKLNM_00588	7.22e-07	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HALMKLNM_00589	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HALMKLNM_00590	0.0	-	-	-	S	-	-	-	membrane
HALMKLNM_00591	3.03e-104	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HALMKLNM_00592	3.8e-265	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HALMKLNM_00593	6.81e-128	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
HALMKLNM_00594	1.44e-177	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HALMKLNM_00596	1.68e-22	-	-	-	-	-	-	-	-
HALMKLNM_00597	2.93e-254	oatA	-	-	I	-	-	-	Acyltransferase
HALMKLNM_00598	1.65e-272	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HALMKLNM_00599	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HALMKLNM_00600	1.21e-178	-	1.1.1.29	-	C	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HALMKLNM_00603	1.2e-51	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HALMKLNM_00604	4.2e-92	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HALMKLNM_00605	3.55e-79	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HALMKLNM_00606	5.23e-54	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HALMKLNM_00607	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HALMKLNM_00608	8.48e-19	cvpA	-	-	S	-	-	-	Colicin V production protein
HALMKLNM_00609	3.67e-17	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HALMKLNM_00610	4.23e-44	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HALMKLNM_00611	3.16e-78	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HALMKLNM_00612	2.44e-49	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HALMKLNM_00613	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HALMKLNM_00614	3.02e-236	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HALMKLNM_00615	3.08e-154	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HALMKLNM_00616	7.06e-18	-	-	-	-	-	-	-	-
HALMKLNM_00617	2.25e-183	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HALMKLNM_00618	3.61e-84	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
HALMKLNM_00619	1.65e-309	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
HALMKLNM_00620	3.54e-150	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
HALMKLNM_00621	2.92e-264	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HALMKLNM_00623	3.61e-79	uspA3	-	-	T	-	-	-	universal stress protein
HALMKLNM_00625	3.02e-20	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
HALMKLNM_00626	1.46e-263	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HALMKLNM_00627	1.66e-230	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HALMKLNM_00628	4.14e-193	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HALMKLNM_00629	8.88e-91	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HALMKLNM_00630	2.31e-286	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HALMKLNM_00631	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HALMKLNM_00632	8.83e-256	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HALMKLNM_00633	1.84e-203	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HALMKLNM_00634	1.41e-109	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HALMKLNM_00635	2.92e-84	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HALMKLNM_00636	1.82e-116	ymfI	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HALMKLNM_00637	1.12e-185	ymfH	-	-	S	-	-	-	Peptidase M16
HALMKLNM_00638	7.37e-137	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HALMKLNM_00639	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HALMKLNM_00640	2.62e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HALMKLNM_00641	3.52e-125	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HALMKLNM_00642	1.44e-83	-	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
HALMKLNM_00643	9.29e-207	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HALMKLNM_00644	6.01e-251	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HALMKLNM_00645	8.63e-113	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HALMKLNM_00646	4.44e-10	llrE	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HALMKLNM_00647	1.73e-23	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HALMKLNM_00648	3.57e-162	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HALMKLNM_00649	1.12e-38	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HALMKLNM_00650	1.57e-284	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HALMKLNM_00651	3.21e-87	ybbR	-	-	S	-	-	-	YbbR-like protein
HALMKLNM_00652	1.95e-162	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HALMKLNM_00653	3.92e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
HALMKLNM_00654	4.95e-145	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HALMKLNM_00655	3.34e-90	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HALMKLNM_00656	1e-72	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HALMKLNM_00657	7.01e-181	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HALMKLNM_00658	2.16e-134	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HALMKLNM_00659	6.82e-148	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HALMKLNM_00660	1.37e-53	-	-	-	-	-	-	-	-
HALMKLNM_00661	4.3e-91	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HALMKLNM_00662	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HALMKLNM_00663	1.19e-32	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HALMKLNM_00664	3.63e-223	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HALMKLNM_00665	1.54e-188	-	-	-	E	-	-	-	Major Facilitator Superfamily
HALMKLNM_00666	8.04e-212	yclK	-	-	T	-	-	-	Histidine kinase
HALMKLNM_00667	1.6e-133	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HALMKLNM_00668	2.02e-167	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HALMKLNM_00669	8.74e-298	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HALMKLNM_00670	9.95e-165	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HALMKLNM_00671	6.65e-263	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HALMKLNM_00672	1.19e-231	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HALMKLNM_00673	1.85e-173	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HALMKLNM_00675	2.07e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HALMKLNM_00676	2.05e-191	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HALMKLNM_00677	4.52e-195	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HALMKLNM_00678	7.15e-161	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HALMKLNM_00679	7.97e-102	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
HALMKLNM_00680	1.23e-107	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HALMKLNM_00681	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HALMKLNM_00682	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HALMKLNM_00683	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HALMKLNM_00684	4.11e-143	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HALMKLNM_00685	4.12e-168	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HALMKLNM_00686	3.44e-35	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HALMKLNM_00687	1.02e-10	-	-	-	K	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HALMKLNM_00688	9.27e-105	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HALMKLNM_00689	2.41e-109	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HALMKLNM_00690	1.4e-80	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HALMKLNM_00691	6.47e-207	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HALMKLNM_00692	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HALMKLNM_00693	1.57e-118	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
HALMKLNM_00694	1.74e-105	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HALMKLNM_00695	1.13e-68	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HALMKLNM_00696	1.51e-159	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HALMKLNM_00697	3.75e-200	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HALMKLNM_00698	0.0	ydaO	-	-	E	-	-	-	amino acid
HALMKLNM_00699	0.0	-	-	-	P	ko:K12952	-	ko00000,ko01000	COG COG0474 Cation transport ATPase
HALMKLNM_00700	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HALMKLNM_00701	1.7e-46	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HALMKLNM_00702	1.28e-39	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HALMKLNM_00703	5.32e-127	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HALMKLNM_00704	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HALMKLNM_00705	3.96e-203	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HALMKLNM_00706	2.77e-29	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HALMKLNM_00707	3.01e-87	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HALMKLNM_00708	2.82e-178	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HALMKLNM_00709	3.47e-104	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HALMKLNM_00710	3.66e-133	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HALMKLNM_00711	3.85e-52	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HALMKLNM_00712	1.19e-105	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HALMKLNM_00713	3.09e-83	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HALMKLNM_00714	2.93e-39	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HALMKLNM_00715	6.62e-126	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HALMKLNM_00716	3.8e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HALMKLNM_00717	1.16e-269	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HALMKLNM_00718	2.23e-80	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HALMKLNM_00719	1.11e-96	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HALMKLNM_00720	1.36e-37	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HALMKLNM_00721	1.81e-58	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
HALMKLNM_00722	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HALMKLNM_00723	1.1e-203	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HALMKLNM_00724	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HALMKLNM_00725	4.43e-72	-	-	-	-	-	-	-	-
HALMKLNM_00726	2.18e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HALMKLNM_00727	3.15e-97	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HALMKLNM_00728	9.98e-150	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HALMKLNM_00729	2.58e-88	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HALMKLNM_00730	3.13e-109	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HALMKLNM_00731	3.08e-16	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HALMKLNM_00732	3.2e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HALMKLNM_00733	1.93e-92	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HALMKLNM_00734	1.32e-138	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HALMKLNM_00735	1.71e-73	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HALMKLNM_00736	1.59e-263	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HALMKLNM_00737	1.22e-311	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HALMKLNM_00738	1.38e-195	yacL	-	-	S	-	-	-	domain protein
HALMKLNM_00739	8e-284	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HALMKLNM_00740	4.81e-95	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HALMKLNM_00741	5.52e-24	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HALMKLNM_00742	7.36e-281	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HALMKLNM_00744	1.34e-39	-	-	-	S	-	-	-	Enterocin A Immunity
HALMKLNM_00745	4.1e-109	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HALMKLNM_00746	1.23e-162	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HALMKLNM_00747	1.87e-148	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HALMKLNM_00749	3.25e-54	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HALMKLNM_00750	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HALMKLNM_00751	1.08e-164	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HALMKLNM_00752	1.26e-306	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HALMKLNM_00753	9.98e-115	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HALMKLNM_00754	9.25e-124	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HALMKLNM_00755	3.02e-115	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HALMKLNM_00758	4.29e-260	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HALMKLNM_00759	8.96e-91	-	-	-	L	ko:K07498	-	ko00000	Transposase IS66 family
HALMKLNM_00760	7.04e-55	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HALMKLNM_00761	2.48e-161	-	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
HALMKLNM_00762	7.24e-121	-	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
HALMKLNM_00763	1.97e-39	-	-	-	L	ko:K07498	-	ko00000	Transposase IS66 family
HALMKLNM_00764	3.24e-34	-	-	-	L	ko:K07498	-	ko00000	Transposase
HALMKLNM_00765	2.14e-67	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
HALMKLNM_00766	6.37e-122	-	-	-	L	-	-	-	Probable transposase
HALMKLNM_00767	1.6e-78	-	-	-	L	-	-	-	Resolvase, N-terminal domain
HALMKLNM_00768	3.22e-140	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HALMKLNM_00769	1.23e-34	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
HALMKLNM_00770	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HALMKLNM_00771	1.73e-49	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HALMKLNM_00772	2.06e-32	-	-	-	-	-	-	-	-
HALMKLNM_00774	3.55e-47	-	-	-	S	-	-	-	Enterocin A Immunity
HALMKLNM_00775	1.12e-100	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
HALMKLNM_00776	3.25e-75	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HALMKLNM_00777	2.23e-147	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HALMKLNM_00778	1.56e-185	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HALMKLNM_00779	7.81e-215	potE2	-	-	E	ko:K03294	-	ko00000	amino acid
HALMKLNM_00782	2.61e-16	-	-	-	-	-	-	-	-
HALMKLNM_00786	0.0	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
HALMKLNM_00787	0.0	-	-	-	V	-	-	-	DNA restriction-modification system
HALMKLNM_00788	4.9e-129	-	-	-	I	-	-	-	PLD-like domain
HALMKLNM_00789	1.11e-20	-	-	-	L	-	-	-	T/G mismatch-specific endonuclease activity
HALMKLNM_00791	2.23e-62	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HALMKLNM_00793	9.15e-134	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HALMKLNM_00794	3.22e-28	-	-	-	S	-	-	-	YjcQ protein
HALMKLNM_00796	6.28e-28	-	-	-	L	-	-	-	Transposase IS116/IS110/IS902 family
HALMKLNM_00797	5.14e-75	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
HALMKLNM_00798	1.66e-174	-	-	-	EG	ko:K06155	-	ko00000,ko02000	Gluconate
HALMKLNM_00799	6.34e-190	-	-	-	S	-	-	-	Protein conserved in bacteria
HALMKLNM_00800	2.8e-141	garR	1.1.1.60	-	I	ko:K00042	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HALMKLNM_00801	1.63e-70	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HALMKLNM_00802	9.95e-54	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HALMKLNM_00804	1.49e-223	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HALMKLNM_00805	7.47e-213	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HALMKLNM_00806	2.72e-230	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HALMKLNM_00807	2.52e-290	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HALMKLNM_00808	1.35e-186	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HALMKLNM_00809	2.03e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HALMKLNM_00810	1.96e-78	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HALMKLNM_00811	2.52e-17	-	-	-	-	-	-	-	-
HALMKLNM_00812	3.81e-37	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HALMKLNM_00813	6.55e-280	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HALMKLNM_00814	8e-111	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HALMKLNM_00815	1.11e-190	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HALMKLNM_00816	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HALMKLNM_00817	2.85e-57	cps3F	-	-	-	-	-	-	-
HALMKLNM_00818	1.28e-107	-	-	-	S	-	-	-	Membrane
HALMKLNM_00819	0.0	-	-	-	E	-	-	-	Amino acid permease
HALMKLNM_00820	8.92e-228	cadA	-	-	P	-	-	-	P-type ATPase
HALMKLNM_00821	1.59e-47	cadA	-	-	P	-	-	-	P-type ATPase
HALMKLNM_00822	1.01e-145	degV	-	-	S	-	-	-	EDD domain protein, DegV family
HALMKLNM_00823	6.83e-188	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HALMKLNM_00824	9.62e-69	-	-	-	F	-	-	-	glutamine amidotransferase
HALMKLNM_00825	1.43e-35	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
HALMKLNM_00826	6.07e-186	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HALMKLNM_00827	2.4e-49	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HALMKLNM_00828	7.97e-110	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HALMKLNM_00829	1.18e-103	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HALMKLNM_00830	9.44e-208	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
HALMKLNM_00831	2e-19	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HALMKLNM_00832	1.04e-284	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HALMKLNM_00833	3.22e-157	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HALMKLNM_00834	1.39e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HALMKLNM_00835	3.86e-154	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HALMKLNM_00836	1.91e-106	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HALMKLNM_00837	3.04e-71	lssY	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
HALMKLNM_00838	2.9e-14	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HALMKLNM_00839	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HALMKLNM_00840	1.59e-86	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HALMKLNM_00841	7.55e-308	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HALMKLNM_00842	1.6e-262	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HALMKLNM_00843	2.55e-65	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
HALMKLNM_00844	4.05e-119	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HALMKLNM_00845	1.08e-117	dedA	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HALMKLNM_00846	4.54e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HALMKLNM_00847	1.19e-145	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HALMKLNM_00848	6.45e-79	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HALMKLNM_00849	9.2e-73	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HALMKLNM_00850	1.22e-238	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HALMKLNM_00851	1.41e-123	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HALMKLNM_00855	1.42e-17	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
HALMKLNM_00856	4.34e-36	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HALMKLNM_00857	7.88e-122	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HALMKLNM_00858	2.24e-152	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HALMKLNM_00859	1.16e-129	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HALMKLNM_00860	4e-153	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HALMKLNM_00861	4.81e-54	-	-	-	S	-	-	-	VanZ like family
HALMKLNM_00862	1.26e-202	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HALMKLNM_00863	9.17e-219	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HALMKLNM_00864	8.56e-39	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
HALMKLNM_00865	2.25e-111	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HALMKLNM_00867	2.23e-10	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HALMKLNM_00869	9.82e-96	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HALMKLNM_00870	3.39e-47	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HALMKLNM_00871	8.68e-83	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HALMKLNM_00872	1.97e-53	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HALMKLNM_00873	2.71e-107	-	-	-	S	-	-	-	membrane
HALMKLNM_00874	1.39e-100	-	-	-	S	-	-	-	VIT family
HALMKLNM_00875	3.48e-188	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HALMKLNM_00876	9.13e-73	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HALMKLNM_00877	1.06e-147	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HALMKLNM_00878	1.24e-145	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HALMKLNM_00879	1.35e-154	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HALMKLNM_00880	2.58e-150	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HALMKLNM_00881	3.06e-125	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HALMKLNM_00882	1.01e-53	yjbH	-	-	Q	-	-	-	Thioredoxin
HALMKLNM_00883	9.03e-284	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HALMKLNM_00884	1.32e-85	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HALMKLNM_00885	4.74e-63	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HALMKLNM_00886	1.78e-273	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HALMKLNM_00890	7.64e-121	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HALMKLNM_00891	7.21e-169	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HALMKLNM_00892	9.86e-200	-	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HALMKLNM_00893	2.06e-192	-	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HALMKLNM_00894	1.41e-129	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HALMKLNM_00895	3.97e-136	-	-	-	-	-	-	-	-
HALMKLNM_00896	3.17e-51	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HALMKLNM_00897	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HALMKLNM_00898	6.8e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HALMKLNM_00899	2.49e-133	pncA	-	-	Q	-	-	-	Isochorismatase family
HALMKLNM_00900	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HALMKLNM_00901	8.38e-169	-	-	-	F	-	-	-	NUDIX domain
HALMKLNM_00902	5.57e-80	-	-	-	V	-	-	-	HNH endonuclease
HALMKLNM_00904	1.28e-184	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HALMKLNM_00905	6.23e-187	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HALMKLNM_00906	7.22e-107	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HALMKLNM_00907	2.14e-141	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HALMKLNM_00908	1.25e-250	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HALMKLNM_00909	2.65e-35	-	-	-	-	-	-	-	-
HALMKLNM_00910	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HALMKLNM_00911	2.88e-77	-	-	-	T	-	-	-	Universal stress protein family
HALMKLNM_00913	5.42e-272	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HALMKLNM_00914	3.5e-214	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HALMKLNM_00915	0.0	-	-	-	L	-	-	-	MobA MobL family protein
HALMKLNM_00916	1.29e-32	-	-	-	-	-	-	-	-
HALMKLNM_00917	2.09e-55	-	-	-	-	-	-	-	-
HALMKLNM_00918	7.56e-83	-	-	-	S	-	-	-	protein conserved in bacteria
HALMKLNM_00919	1.58e-38	-	-	-	S	-	-	-	protein conserved in bacteria
HALMKLNM_00920	3.96e-37	-	-	-	-	-	-	-	-
HALMKLNM_00921	2.83e-58	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
HALMKLNM_00922	2.49e-178	-	-	-	S	-	-	-	Fic/DOC family
HALMKLNM_00923	5.03e-35	-	-	-	-	-	-	-	-
HALMKLNM_00924	1.67e-241	repA	-	-	S	-	-	-	Replication initiator protein A
HALMKLNM_00925	4.18e-46	-	-	-	-	-	-	-	-
HALMKLNM_00926	6.36e-190	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HALMKLNM_00927	1.74e-74	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
HALMKLNM_00928	8.46e-65	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HALMKLNM_00929	1.2e-94	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
HALMKLNM_00930	4.18e-75	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HALMKLNM_00931	3.13e-35	-	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
HALMKLNM_00932	2.24e-15	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HALMKLNM_00933	2.2e-202	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HALMKLNM_00934	2.57e-60	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HALMKLNM_00935	2.44e-104	-	-	-	-	-	-	-	-
HALMKLNM_00936	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HALMKLNM_00937	5.19e-34	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HALMKLNM_00938	6.13e-86	-	-	-	L	ko:K07498	-	ko00000	Transposase
HALMKLNM_00939	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
HALMKLNM_00940	4.7e-43	-	-	-	P	-	-	-	Heavy-metal-associated domain
HALMKLNM_00941	3.6e-97	-	-	-	K	-	-	-	SIR2-like domain
HALMKLNM_00942	7.64e-27	-	-	-	-	-	-	-	-
HALMKLNM_00943	6.37e-141	-	-	-	K	-	-	-	IrrE N-terminal-like domain
HALMKLNM_00945	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HALMKLNM_00946	2.4e-214	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HALMKLNM_00947	3.77e-166	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HALMKLNM_00948	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HALMKLNM_00949	2.49e-100	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HALMKLNM_00950	3.67e-117	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HALMKLNM_00951	1.23e-62	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HALMKLNM_00952	1.49e-28	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HALMKLNM_00953	1.1e-42	yabO	-	-	J	-	-	-	S4 domain protein
HALMKLNM_00954	4.66e-173	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HALMKLNM_00955	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HALMKLNM_00956	1.68e-94	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HALMKLNM_00957	8.16e-202	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HALMKLNM_00958	2.2e-110	-	-	-	S	-	-	-	(CBS) domain
HALMKLNM_00959	6.3e-180	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HALMKLNM_00960	3.51e-262	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HALMKLNM_00961	1.43e-68	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HALMKLNM_00962	4.71e-72	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
HALMKLNM_00963	1.27e-131	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HALMKLNM_00964	2.18e-144	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HALMKLNM_00965	1.72e-60	-	-	-	M	-	-	-	LysM domain protein
HALMKLNM_00966	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HALMKLNM_00967	6.4e-111	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HALMKLNM_00968	5.22e-42	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
HALMKLNM_00969	1.72e-142	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HALMKLNM_00970	3.3e-113	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HALMKLNM_00971	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HALMKLNM_00972	5.67e-307	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HALMKLNM_00974	2.29e-79	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HALMKLNM_00975	1.04e-99	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HALMKLNM_00976	4.38e-160	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HALMKLNM_00977	3.1e-138	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HALMKLNM_00978	1.24e-139	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HALMKLNM_00979	1.31e-126	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HALMKLNM_00980	4.47e-71	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HALMKLNM_00981	1.93e-198	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HALMKLNM_00982	1.24e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HALMKLNM_00983	7.34e-74	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HALMKLNM_00984	1.72e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HALMKLNM_00985	7.16e-47	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HALMKLNM_00986	8.94e-143	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HALMKLNM_00987	1.05e-266	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HALMKLNM_00988	1.13e-88	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HALMKLNM_00989	1.65e-31	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HALMKLNM_00990	2.08e-106	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HALMKLNM_00991	2.4e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HALMKLNM_00992	4.99e-113	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HALMKLNM_00993	5.17e-86	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HALMKLNM_00994	4.1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HALMKLNM_00995	1.61e-119	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HALMKLNM_00996	3.84e-62	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HALMKLNM_00997	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HALMKLNM_00998	5.05e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HALMKLNM_00999	2.63e-32	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HALMKLNM_01000	8.95e-95	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HALMKLNM_01001	1.62e-149	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HALMKLNM_01002	2.63e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HALMKLNM_01003	5.93e-60	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HALMKLNM_01004	4.58e-183	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HALMKLNM_01005	1.34e-52	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HALMKLNM_01006	6.55e-130	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HALMKLNM_01007	2.82e-140	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HALMKLNM_01008	3.24e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HALMKLNM_01009	2.1e-218	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HALMKLNM_01010	1.07e-100	-	-	-	K	-	-	-	rpiR family
HALMKLNM_01011	1.63e-68	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HALMKLNM_01012	2.05e-172	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HALMKLNM_01013	2.79e-14	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HALMKLNM_01014	1e-240	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HALMKLNM_01015	1.88e-104	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HALMKLNM_01016	4.89e-111	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HALMKLNM_01017	2.79e-125	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HALMKLNM_01018	2.45e-132	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HALMKLNM_01019	1.32e-17	-	-	-	-	-	-	-	-
HALMKLNM_01020	3.67e-122	-	-	-	-	-	-	-	-
HALMKLNM_01021	2.09e-16	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HALMKLNM_01022	2.87e-68	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HALMKLNM_01023	2.5e-268	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HALMKLNM_01024	2.44e-315	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HALMKLNM_01025	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HALMKLNM_01026	1.01e-100	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HALMKLNM_01027	3.39e-232	yhdP	-	-	S	-	-	-	Transporter associated domain
HALMKLNM_01028	7.84e-33	-	-	-	-	-	-	-	-
HALMKLNM_01029	1.13e-93	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HALMKLNM_01030	3.21e-162	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HALMKLNM_01031	2.78e-126	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HALMKLNM_01032	5.65e-92	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HALMKLNM_01033	6.88e-200	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HALMKLNM_01034	1.39e-174	-	-	-	V	-	-	-	MatE
HALMKLNM_01035	1.32e-57	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HALMKLNM_01036	3.17e-110	-	-	-	S	-	-	-	Alpha beta hydrolase
HALMKLNM_01037	1.06e-121	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HALMKLNM_01038	1.5e-218	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HALMKLNM_01039	1.24e-137	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
HALMKLNM_01040	1.49e-129	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HALMKLNM_01041	8.54e-45	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HALMKLNM_01042	1.09e-68	ccl	-	-	S	-	-	-	QueT transporter
HALMKLNM_01044	6.6e-84	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HALMKLNM_01045	2.37e-28	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HALMKLNM_01046	1.91e-29	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HALMKLNM_01047	7.86e-46	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HALMKLNM_01048	1.48e-110	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HALMKLNM_01049	1.52e-157	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HALMKLNM_01050	1.19e-65	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HALMKLNM_01051	9.59e-104	-	-	-	S	-	-	-	Putative threonine/serine exporter
HALMKLNM_01052	1.37e-37	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HALMKLNM_01053	1.77e-115	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
HALMKLNM_01054	1.66e-116	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HALMKLNM_01055	1.71e-27	-	-	-	-	-	-	-	-
HALMKLNM_01056	1.3e-74	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
HALMKLNM_01057	4.48e-24	-	-	-	-	-	-	-	-
HALMKLNM_01058	3.45e-81	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HALMKLNM_01059	6.13e-51	-	-	-	S	-	-	-	branched-chain amino acid
HALMKLNM_01060	3.58e-132	-	-	-	E	-	-	-	AzlC protein
HALMKLNM_01061	2.11e-23	-	-	-	-	-	-	-	-
HALMKLNM_01062	5.1e-163	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HALMKLNM_01063	1.25e-156	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HALMKLNM_01071	2.43e-09	-	-	-	S	-	-	-	Mor transcription activator family
HALMKLNM_01072	3.27e-73	-	-	-	K	-	-	-	WYL domain
HALMKLNM_01073	3.53e-158	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HALMKLNM_01074	4.47e-217	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HALMKLNM_01075	7.91e-149	ydbI	-	-	K	-	-	-	AI-2E family transporter
HALMKLNM_01076	2.37e-75	-	-	-	EG	-	-	-	EamA-like transporter family
HALMKLNM_01077	4.32e-96	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HALMKLNM_01078	1.13e-146	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HALMKLNM_01079	4.46e-86	-	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HALMKLNM_01080	5.43e-209	-	-	-	C	-	-	-	Luciferase-like monooxygenase
HALMKLNM_01081	1.7e-55	hxlR	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HALMKLNM_01082	6.68e-219	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HALMKLNM_01083	2.09e-132	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HALMKLNM_01084	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HALMKLNM_01085	3.43e-106	pncA	-	-	Q	-	-	-	isochorismatase
HALMKLNM_01086	1.14e-81	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HALMKLNM_01087	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HALMKLNM_01088	1.68e-108	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HALMKLNM_01089	8.57e-315	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HALMKLNM_01090	2.77e-211	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HALMKLNM_01092	3.99e-131	XK27_08315	-	-	M	-	-	-	Sulfatase
HALMKLNM_01093	2.51e-105	XK27_08315	-	-	M	-	-	-	Sulfatase
HALMKLNM_01094	2.45e-66	-	-	-	S	-	-	-	peptidoglycan catabolic process
HALMKLNM_01095	6.4e-198	-	-	-	M	-	-	-	Belongs to the BCCT transporter (TC 2.A.15) family
HALMKLNM_01096	8.79e-109	-	-	-	M	-	-	-	Nucleotidyl transferase
HALMKLNM_01097	8.04e-220	-	-	-	M	-	-	-	Choline/ethanolamine kinase
HALMKLNM_01098	4.64e-113	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HALMKLNM_01099	1.46e-213	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HALMKLNM_01100	8.54e-161	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HALMKLNM_01101	2.42e-222	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HALMKLNM_01102	1.18e-152	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
HALMKLNM_01103	4.55e-20	-	-	-	-	-	-	-	-
HALMKLNM_01104	4.67e-91	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HALMKLNM_01105	8.65e-185	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HALMKLNM_01106	6.99e-66	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HALMKLNM_01107	8.36e-196	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HALMKLNM_01108	1.23e-85	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HALMKLNM_01109	3.27e-120	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HALMKLNM_01110	7.97e-206	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HALMKLNM_01111	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HALMKLNM_01113	2.97e-193	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HALMKLNM_01114	9.57e-248	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HALMKLNM_01115	7.09e-43	-	-	-	S	-	-	-	Acyltransferase family
HALMKLNM_01120	2.04e-79	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HALMKLNM_01121	2.14e-92	licD1	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HALMKLNM_01122	1.74e-67	-	-	-	-	-	-	-	-
HALMKLNM_01123	4.73e-116	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HALMKLNM_01124	1.21e-83	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
HALMKLNM_01125	4.86e-115	-	-	-	M	-	-	-	Core-2/I-Branching enzyme
HALMKLNM_01126	6.37e-47	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HALMKLNM_01127	2.95e-80	-	-	-	D	-	-	-	Peptidase family M23
HALMKLNM_01129	2.41e-163	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HALMKLNM_01130	3.12e-214	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HALMKLNM_01131	9.2e-130	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HALMKLNM_01132	9.87e-184	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HALMKLNM_01133	1.19e-115	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
HALMKLNM_01134	7.11e-75	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
HALMKLNM_01135	2.34e-47	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HALMKLNM_01136	3.44e-26	-	-	-	L	ko:K07482	-	ko00000	Integrase
HALMKLNM_01137	4.8e-95	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HALMKLNM_01144	1.94e-40	-	-	-	L	-	-	-	MULE transposase domain
HALMKLNM_01145	4.35e-48	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HALMKLNM_01146	5.89e-60	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
HALMKLNM_01147	7.73e-62	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
HALMKLNM_01148	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HALMKLNM_01149	7.49e-169	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HALMKLNM_01150	3.94e-56	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HALMKLNM_01151	3.91e-143	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HALMKLNM_01152	2e-240	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HALMKLNM_01153	6.18e-267	potE	-	-	E	-	-	-	Amino Acid
HALMKLNM_01154	2.51e-43	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
HALMKLNM_01155	1.78e-171	tetA	-	-	EGP	ko:K08151,ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko01504,ko02000	Major facilitator Superfamily
HALMKLNM_01156	6.25e-77	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HALMKLNM_01157	2.44e-149	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HALMKLNM_01158	2.09e-46	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HALMKLNM_01159	1.3e-114	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HALMKLNM_01160	1.03e-81	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HALMKLNM_01161	5.18e-191	-	-	-	EGP	-	-	-	Major Facilitator
HALMKLNM_01163	1.09e-87	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HALMKLNM_01164	1.29e-32	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
HALMKLNM_01165	7.64e-114	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HALMKLNM_01166	3.49e-130	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HALMKLNM_01167	8.04e-71	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HALMKLNM_01168	6.01e-139	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HALMKLNM_01169	6.5e-126	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HALMKLNM_01170	5.14e-132	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HALMKLNM_01171	2.75e-46	-	-	-	-	-	-	-	-
HALMKLNM_01172	3.04e-20	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HALMKLNM_01173	2.21e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HALMKLNM_01174	2.94e-242	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HALMKLNM_01175	3.11e-33	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HALMKLNM_01176	2.39e-137	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HALMKLNM_01177	4.97e-153	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HALMKLNM_01178	6.46e-85	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HALMKLNM_01179	7.29e-130	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HALMKLNM_01180	4.74e-161	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HALMKLNM_01181	2.48e-89	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HALMKLNM_01182	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HALMKLNM_01183	1.36e-78	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
HALMKLNM_01184	1e-92	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HALMKLNM_01186	2.06e-82	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HALMKLNM_01187	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HALMKLNM_01188	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HALMKLNM_01189	1.75e-45	-	-	-	-	-	-	-	-
HALMKLNM_01190	1.86e-178	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HALMKLNM_01191	1.42e-197	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HALMKLNM_01192	1.57e-123	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HALMKLNM_01193	1.15e-198	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HALMKLNM_01194	4.21e-53	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HALMKLNM_01196	3.12e-121	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HALMKLNM_01197	7.23e-56	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HALMKLNM_01198	2.84e-234	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HALMKLNM_01199	1.63e-85	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HALMKLNM_01200	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HALMKLNM_01201	6.4e-138	-	-	-	P	-	-	-	Integral membrane protein TerC family
HALMKLNM_01202	1.86e-49	-	-	-	K	-	-	-	Transcriptional regulator
HALMKLNM_01203	3.36e-122	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HALMKLNM_01204	1.17e-127	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HALMKLNM_01205	3.9e-134	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HALMKLNM_01206	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HALMKLNM_01207	1.34e-258	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HALMKLNM_01208	2e-220	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HALMKLNM_01209	3.08e-135	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HALMKLNM_01210	1.7e-66	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HALMKLNM_01211	4.9e-89	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HALMKLNM_01212	8.78e-192	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HALMKLNM_01213	1.04e-144	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
HALMKLNM_01214	2.02e-78	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HALMKLNM_01215	6.79e-263	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HALMKLNM_01217	1.68e-140	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HALMKLNM_01218	8.93e-97	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HALMKLNM_01219	4.35e-240	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HALMKLNM_01220	2.67e-45	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HALMKLNM_01221	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HALMKLNM_01222	2.02e-148	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HALMKLNM_01223	2.66e-74	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HALMKLNM_01224	1.71e-97	azlC	-	-	E	-	-	-	branched-chain amino acid
HALMKLNM_01225	1.46e-42	-	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HALMKLNM_01226	2.21e-73	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HALMKLNM_01227	1.8e-69	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HALMKLNM_01228	1.3e-67	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HALMKLNM_01229	8.75e-60	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
HALMKLNM_01230	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HALMKLNM_01231	3.19e-139	dat	2.6.1.21	-	EH	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	PFAM aminotransferase, class IV
HALMKLNM_01233	2.05e-86	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HALMKLNM_01234	7.89e-61	hmpT	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HALMKLNM_01235	1.3e-52	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
HALMKLNM_01237	4.2e-45	aguA	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Porphyromonas-type peptidyl-arginine deiminase
HALMKLNM_01238	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HALMKLNM_01239	2.34e-122	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HALMKLNM_01240	4.5e-25	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HALMKLNM_01245	1.16e-93	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HALMKLNM_01246	9.06e-152	ytbE	-	-	S	-	-	-	reductase
HALMKLNM_01247	1.22e-57	ytcD	-	-	K	-	-	-	HxlR-like helix-turn-helix
HALMKLNM_01248	2.53e-130	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HALMKLNM_01249	4.78e-86	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter
HALMKLNM_01250	1.49e-208	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HALMKLNM_01251	5.58e-69	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HALMKLNM_01252	1.03e-59	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HALMKLNM_01253	1.17e-30	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HALMKLNM_01254	8.69e-190	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HALMKLNM_01256	2.35e-51	-	-	-	K	-	-	-	LytTr DNA-binding domain
HALMKLNM_01257	9.27e-145	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HALMKLNM_01258	5.54e-264	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HALMKLNM_01259	1.85e-21	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HALMKLNM_01260	9.89e-197	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HALMKLNM_01261	3.5e-229	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HALMKLNM_01262	7.43e-217	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HALMKLNM_01263	1.97e-189	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HALMKLNM_01264	2.65e-255	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HALMKLNM_01265	5.46e-276	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HALMKLNM_01266	6.95e-112	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HALMKLNM_01267	7.69e-73	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HALMKLNM_01268	1.28e-77	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
HALMKLNM_01269	2.3e-314	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HALMKLNM_01270	4.15e-26	-	-	-	S	-	-	-	Cupredoxin-like domain
HALMKLNM_01271	5.2e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
HALMKLNM_01272	2.04e-189	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HALMKLNM_01273	1.12e-28	-	-	-	K	-	-	-	transcriptional regulator
HALMKLNM_01274	2.64e-98	-	-	-	S	-	-	-	intracellular protease amidase
HALMKLNM_01275	9.64e-168	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HALMKLNM_01276	3.48e-143	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HALMKLNM_01277	2.06e-291	treC	-	-	G	-	-	-	Psort location Cytoplasmic, score
HALMKLNM_01278	5.79e-51	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HALMKLNM_01279	1.13e-155	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HALMKLNM_01280	7.67e-139	-	-	-	G	-	-	-	PTS system sorbose-specific iic component
HALMKLNM_01281	1.26e-82	-	-	-	G	-	-	-	PTS system sorbose subfamily IIB component
HALMKLNM_01282	6.73e-102	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HALMKLNM_01283	6.87e-177	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HALMKLNM_01284	1.69e-254	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HALMKLNM_01285	1.46e-148	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HALMKLNM_01286	3.57e-242	-	-	-	C	-	-	-	FMN_bind
HALMKLNM_01287	1.13e-70	oxyR5	-	-	K	-	-	-	Transcriptional regulator
HALMKLNM_01288	6.02e-202	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HALMKLNM_01289	7.26e-250	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HALMKLNM_01290	8.35e-71	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HALMKLNM_01291	1.29e-166	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cobalamin-independent synthase, Catalytic domain
HALMKLNM_01292	1.84e-126	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HALMKLNM_01293	4.45e-104	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HALMKLNM_01294	1.28e-12	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HALMKLNM_01296	3.46e-78	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
HALMKLNM_01297	4.26e-200	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HALMKLNM_01299	2.37e-290	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HALMKLNM_01300	1.97e-81	-	-	-	C	-	-	-	FMN binding
HALMKLNM_01301	5.05e-260	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HALMKLNM_01302	9.07e-86	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HALMKLNM_01303	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HALMKLNM_01308	1.38e-113	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HALMKLNM_01309	7.12e-59	deoR_2	-	-	K	-	-	-	Putative sugar-binding domain
HALMKLNM_01310	6.07e-11	-	-	-	K	ko:K02466	-	ko00000	Glucitol operon activator protein (GutM)
HALMKLNM_01311	2e-138	pts38BC	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HALMKLNM_01312	2.31e-94	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HALMKLNM_01313	5.59e-16	-	-	-	G	-	-	-	PTS system glucitol/sorbitol-specific IIA component
HALMKLNM_01314	3.08e-237	-	-	-	E	-	-	-	SAF
HALMKLNM_01315	5.18e-145	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HALMKLNM_01316	1.72e-05	iolG2	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HALMKLNM_01317	8.11e-225	-	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HALMKLNM_01318	4.25e-161	iolG	1.1.1.18, 1.1.1.369	-	C	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HALMKLNM_01319	1.16e-54	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HALMKLNM_01320	6.87e-127	-	-	-	K	-	-	-	IrrE N-terminal-like domain
HALMKLNM_01321	4.97e-76	-	-	-	-	-	-	-	-
HALMKLNM_01322	2.26e-48	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HALMKLNM_01323	3.7e-15	-	-	-	L	-	-	-	hmm pf00665
HALMKLNM_01324	1.71e-66	-	-	-	L	-	-	-	Helix-turn-helix domain
HALMKLNM_01325	1.8e-272	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HALMKLNM_01327	3.7e-24	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HALMKLNM_01328	5.98e-52	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
HALMKLNM_01329	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HALMKLNM_01330	6.21e-07	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HALMKLNM_01331	1.67e-46	-	-	-	-	-	-	-	-
HALMKLNM_01333	3.22e-161	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HALMKLNM_01334	8.57e-12	bglG	-	-	K	ko:K03488	-	ko00000,ko03000	antiterminator
HALMKLNM_01335	2.04e-45	licT	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HALMKLNM_01336	7.1e-254	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Pts system
HALMKLNM_01337	8.02e-214	ascB	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HALMKLNM_01338	7.29e-45	-	-	-	S	-	-	-	Replication initiator protein A (RepA) N-terminus
HALMKLNM_01339	1.32e-141	-	-	-	L	-	-	-	Initiator Replication protein
HALMKLNM_01342	6.98e-174	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HALMKLNM_01343	4.77e-11	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HALMKLNM_01344	1.91e-287	fusA1	-	-	J	-	-	-	elongation factor G
HALMKLNM_01345	3.83e-43	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HALMKLNM_01346	4.74e-08	-	-	-	-	-	-	-	-
HALMKLNM_01347	1.92e-270	potE	-	-	E	-	-	-	Amino Acid
HALMKLNM_01348	2.46e-78	yphA	-	-	GM	-	-	-	NAD dependent epimerase/dehydratase family
HALMKLNM_01349	4.68e-95	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HALMKLNM_01350	2.52e-118	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HALMKLNM_01351	8.86e-162	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HALMKLNM_01352	4.36e-116	nanK	-	-	GK	-	-	-	ROK family
HALMKLNM_01353	4.37e-70	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HALMKLNM_01354	3.08e-75	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HALMKLNM_01355	1.09e-191	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HALMKLNM_01356	9.72e-258	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HALMKLNM_01357	3.18e-95	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HALMKLNM_01358	5.2e-94	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HALMKLNM_01359	1.05e-143	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HALMKLNM_01360	5.79e-54	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HALMKLNM_01361	3.22e-86	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HALMKLNM_01362	2.66e-102	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HALMKLNM_01363	4.02e-237	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HALMKLNM_01365	1.69e-19	-	-	-	-	-	-	-	-
HALMKLNM_01366	4.22e-113	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HALMKLNM_01367	7.3e-48	blpT	-	-	-	-	-	-	-
HALMKLNM_01368	1.3e-08	ps105	-	-	-	-	-	-	-
HALMKLNM_01377	1.62e-61	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HALMKLNM_01378	4.13e-64	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HALMKLNM_01383	2.44e-89	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HALMKLNM_01384	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
HALMKLNM_01385	1.63e-214	-	-	-	M	-	-	-	YSIRK type signal peptide
HALMKLNM_01386	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HALMKLNM_01387	6.42e-125	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HALMKLNM_01388	6.35e-206	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
HALMKLNM_01389	2.38e-141	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HALMKLNM_01390	7.16e-94	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HALMKLNM_01391	7.01e-57	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HALMKLNM_01392	1.12e-105	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HALMKLNM_01393	1.73e-171	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HALMKLNM_01394	2.21e-47	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HALMKLNM_01395	1.26e-79	mipB	2.2.1.2	-	H	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
HALMKLNM_01396	3.14e-147	ddh	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HALMKLNM_01397	3.83e-173	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HALMKLNM_01399	2.2e-91	bsaB	-	-	S	ko:K20483	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lantibiotic dehydratase, C terminus
HALMKLNM_01400	1.14e-147	bsaB	-	-	S	ko:K20483	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lantibiotic dehydratase, C terminus
HALMKLNM_01401	2.13e-227	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ATPases associated with a variety of cellular activities
HALMKLNM_01402	9.45e-92	spaC1	-	-	V	ko:K20484	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lanthionine synthetase C-like protein
HALMKLNM_01403	1.61e-113	spaR	-	-	KT	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HALMKLNM_01404	5.88e-130	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HALMKLNM_01405	1.06e-92	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HALMKLNM_01406	6e-42	-	-	-	S	-	-	-	ABC-2 family transporter protein
HALMKLNM_01408	3.04e-36	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HALMKLNM_01409	4.72e-26	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
HALMKLNM_01411	2.22e-281	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HALMKLNM_01412	5.23e-148	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HALMKLNM_01413	7.04e-178	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HALMKLNM_01414	2.42e-183	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HALMKLNM_01415	1.15e-53	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HALMKLNM_01416	2.63e-303	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HALMKLNM_01417	5.44e-63	-	-	-	S	-	-	-	VIT family
HALMKLNM_01418	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HALMKLNM_01419	5.49e-175	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HALMKLNM_01420	2.15e-141	rssA	-	-	S	-	-	-	Phospholipase, patatin family
HALMKLNM_01421	3.76e-18	-	-	-	-	-	-	-	-
HALMKLNM_01422	1.22e-22	-	-	-	-	-	-	-	-
HALMKLNM_01423	5e-100	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HALMKLNM_01424	1.15e-126	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HALMKLNM_01425	8.46e-101	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HALMKLNM_01426	1.94e-67	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HALMKLNM_01427	2.17e-73	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HALMKLNM_01428	2.89e-98	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HALMKLNM_01429	5.78e-39	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HALMKLNM_01430	4.32e-33	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HALMKLNM_01431	1.04e-130	bsh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HALMKLNM_01435	6.28e-181	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase family
HALMKLNM_01436	5.6e-90	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HALMKLNM_01437	8.49e-175	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HALMKLNM_01438	3.42e-270	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HALMKLNM_01439	1.73e-148	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HALMKLNM_01440	7.4e-177	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HALMKLNM_01441	6.52e-90	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HALMKLNM_01442	4.02e-122	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HALMKLNM_01443	3.56e-166	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HALMKLNM_01446	4.95e-184	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HALMKLNM_01447	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HALMKLNM_01448	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HALMKLNM_01449	6.9e-205	camS	-	-	S	-	-	-	sex pheromone
HALMKLNM_01450	1.34e-50	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HALMKLNM_01451	5.93e-294	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HALMKLNM_01452	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HALMKLNM_01453	8.82e-184	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HALMKLNM_01454	8.77e-268	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HALMKLNM_01456	0.0	mcrB	-	-	V	ko:K07452	-	ko00000,ko01000,ko02048	ATPase family associated with various cellular activities (AAA)
HALMKLNM_01457	1.21e-212	mcrC	-	-	V	ko:K19147	-	ko00000,ko02048	Psort location Cytoplasmic, score
HALMKLNM_01458	1.41e-285	mod	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
HALMKLNM_01459	0.0	res	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
HALMKLNM_01460	0.0	-	-	-	L	-	-	-	helicase activity
HALMKLNM_01461	2.62e-133	-	-	-	S	-	-	-	Domain of unknown function (DUF4343)
HALMKLNM_01462	1.22e-74	-	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
HALMKLNM_01464	1.12e-55	-	-	-	S	-	-	-	Domain of unknown function (DUF3841)
HALMKLNM_01465	7.03e-208	spoVK	-	-	O	ko:K06413	-	ko00000	PFAM ATPase family associated with various cellular activities (AAA)
HALMKLNM_01466	7.27e-200	-	-	-	C	-	-	-	Oxidoreductase
HALMKLNM_01467	5.1e-92	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HALMKLNM_01468	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HALMKLNM_01469	2.11e-122	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HALMKLNM_01470	6e-76	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HALMKLNM_01471	7.05e-222	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HALMKLNM_01472	2.77e-19	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
HALMKLNM_01473	4.35e-301	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HALMKLNM_01474	1.13e-248	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HALMKLNM_01475	1.8e-267	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HALMKLNM_01476	3.36e-48	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HALMKLNM_01477	1.54e-203	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HALMKLNM_01478	9.53e-79	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
HALMKLNM_01479	1.7e-129	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HALMKLNM_01481	6.98e-285	-	-	-	M	-	-	-	Rib/alpha-like repeat
HALMKLNM_01482	2.15e-59	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HALMKLNM_01483	2.3e-78	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HALMKLNM_01484	1.17e-52	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HALMKLNM_01485	2.99e-73	napB	-	-	K	-	-	-	transcriptional
HALMKLNM_01486	6.45e-89	mleR	-	-	K	-	-	-	LysR family
HALMKLNM_01487	4.83e-313	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HALMKLNM_01488	1.24e-161	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HALMKLNM_01489	8.09e-82	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HALMKLNM_01490	2.58e-77	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HALMKLNM_01491	1.6e-95	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HALMKLNM_01492	9.01e-254	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HALMKLNM_01493	2.27e-48	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HALMKLNM_01494	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HALMKLNM_01495	5.56e-124	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HALMKLNM_01496	1.79e-148	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HALMKLNM_01497	7.5e-118	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HALMKLNM_01498	4.46e-229	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HALMKLNM_01500	1.96e-54	-	-	-	-	-	-	-	-
HALMKLNM_01501	1.87e-41	-	-	-	K	-	-	-	GNAT family
HALMKLNM_01502	1.13e-262	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HALMKLNM_01503	1.46e-277	gdhA	1.4.1.3, 1.4.1.4	-	E	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	ko00000,ko00001,ko00002,ko01000,ko04147	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
HALMKLNM_01504	2.8e-46	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HALMKLNM_01505	8.86e-274	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HALMKLNM_01506	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HALMKLNM_01507	1.95e-208	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HALMKLNM_01508	1.94e-157	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HALMKLNM_01509	1.82e-243	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HALMKLNM_01510	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HALMKLNM_01511	9.89e-215	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HALMKLNM_01512	1.13e-32	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HALMKLNM_01513	7.62e-161	mocA	-	-	S	-	-	-	Oxidoreductase
HALMKLNM_01514	2.29e-200	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HALMKLNM_01517	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HALMKLNM_01518	4.67e-126	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HALMKLNM_01519	1.05e-271	-	-	-	G	ko:K16211	-	ko00000,ko02000	Transporter, major facilitator family protein
HALMKLNM_01520	3.1e-94	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HALMKLNM_01521	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HALMKLNM_01522	2.23e-110	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HALMKLNM_01523	1.67e-213	-	-	-	E	-	-	-	Amino acid permease
HALMKLNM_01524	1.92e-106	-	-	-	E	-	-	-	Amino acid permease
HALMKLNM_01525	7.04e-229	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
HALMKLNM_01526	1.92e-213	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HALMKLNM_01527	4.88e-90	-	-	-	K	-	-	-	Sugar-specific transcriptional regulator TrmB
HALMKLNM_01528	1.52e-153	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HALMKLNM_01529	8.01e-151	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
HALMKLNM_01530	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HALMKLNM_01531	5.64e-69	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HALMKLNM_01532	2.18e-69	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HALMKLNM_01533	3.03e-183	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HALMKLNM_01534	5.63e-195	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HALMKLNM_01535	2.24e-16	-	3.5.1.28	CBM50	M	ko:K22409	-	ko00000,ko01000	Lysin motif
HALMKLNM_01536	5.57e-118	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HALMKLNM_01539	3.97e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF4256)
HALMKLNM_01540	7e-161	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HALMKLNM_01541	1.02e-73	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HALMKLNM_01542	1.26e-191	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HALMKLNM_01544	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
HALMKLNM_01545	4.28e-214	npr	1.11.1.1	-	S	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HALMKLNM_01546	1.16e-136	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
HALMKLNM_01547	1.44e-104	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HALMKLNM_01548	2.84e-107	-	-	-	C	-	-	-	nitroreductase
HALMKLNM_01549	5.29e-167	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HALMKLNM_01550	5.23e-119	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HALMKLNM_01551	2.65e-188	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HALMKLNM_01552	6.31e-137	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HALMKLNM_01553	1.04e-178	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HALMKLNM_01554	1.03e-59	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
HALMKLNM_01555	1.23e-77	yphH	-	-	S	-	-	-	Cupin domain
HALMKLNM_01556	1.56e-62	-	-	-	C	-	-	-	Flavodoxin
HALMKLNM_01557	1.99e-70	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HALMKLNM_01558	1.56e-131	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
HALMKLNM_01559	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HALMKLNM_01560	6.13e-286	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HALMKLNM_01561	1.62e-70	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HALMKLNM_01562	2.89e-86	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HALMKLNM_01563	8.15e-138	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HALMKLNM_01564	9.74e-147	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HALMKLNM_01565	7.9e-169	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HALMKLNM_01566	5.67e-202	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HALMKLNM_01567	1.03e-131	potC	-	-	U	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HALMKLNM_01568	3.85e-153	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HALMKLNM_01569	8.99e-212	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HALMKLNM_01570	2.69e-129	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HALMKLNM_01571	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HALMKLNM_01572	4.13e-296	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HALMKLNM_01575	8.46e-23	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HALMKLNM_01576	1.23e-08	-	-	-	S	-	-	-	Putative adhesin
HALMKLNM_01577	1.69e-29	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HALMKLNM_01578	3.6e-51	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
HALMKLNM_01579	7.54e-39	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
HALMKLNM_01580	7.44e-51	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HALMKLNM_01581	4.01e-138	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HALMKLNM_01582	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HALMKLNM_01583	7.26e-43	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HALMKLNM_01584	4.73e-97	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HALMKLNM_01585	4.49e-209	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HALMKLNM_01586	1.66e-163	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HALMKLNM_01587	1.58e-90	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HALMKLNM_01588	1.61e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
HALMKLNM_01589	6.92e-189	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HALMKLNM_01590	1.69e-153	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HALMKLNM_01591	1.11e-192	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HALMKLNM_01592	4.36e-101	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	sugar-binding domain protein
HALMKLNM_01593	2.8e-126	baeS	-	-	T	-	-	-	Histidine kinase
HALMKLNM_01594	1.07e-101	yfiK	-	-	K	ko:K02479	-	ko00000,ko02022	Bacterial regulatory proteins, luxR family
HALMKLNM_01595	4.81e-147	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HALMKLNM_01596	1.29e-51	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HALMKLNM_01597	2.49e-43	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HALMKLNM_01598	2e-246	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HALMKLNM_01599	7.87e-48	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HALMKLNM_01600	5.68e-108	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HALMKLNM_01601	1.34e-75	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HALMKLNM_01602	1.31e-90	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HALMKLNM_01603	6.94e-114	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HALMKLNM_01604	7.03e-228	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HALMKLNM_01605	0.0	-	3.2.1.80	-	GN	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Fructan beta-fructosidase
HALMKLNM_01606	5.14e-69	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HALMKLNM_01607	4.52e-109	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HALMKLNM_01608	5.71e-28	-	-	-	-	-	-	-	-
HALMKLNM_01609	2.69e-18	-	-	-	M	-	-	-	Glycosyl transferase family 2
HALMKLNM_01610	2.27e-67	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HALMKLNM_01611	2.66e-75	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
HALMKLNM_01612	1.2e-144	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HALMKLNM_01613	9.07e-228	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HALMKLNM_01614	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HALMKLNM_01615	1.28e-269	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HALMKLNM_01616	1.32e-185	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HALMKLNM_01617	1.46e-60	-	-	-	M	-	-	-	MucBP domain
HALMKLNM_01618	6.82e-235	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HALMKLNM_01619	5.96e-67	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
HALMKLNM_01620	7.37e-175	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HALMKLNM_01621	6.83e-72	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HALMKLNM_01622	3.21e-256	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HALMKLNM_01623	2.62e-215	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HALMKLNM_01624	1.8e-26	rimL	1.1.1.25	-	J	ko:K00014,ko:K03817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HALMKLNM_01626	1.17e-140	dkgB	-	-	S	-	-	-	reductase
HALMKLNM_01627	5.45e-35	-	-	-	-	-	-	-	-
HALMKLNM_01628	3.22e-98	-	-	-	F	-	-	-	Phosphorylase superfamily
HALMKLNM_01629	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HALMKLNM_01630	8.06e-78	ytkL	-	-	S	-	-	-	Beta-lactamase superfamily domain
HALMKLNM_01631	1e-123	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HALMKLNM_01632	9.11e-156	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HALMKLNM_01633	4.08e-111	-	-	-	S	-	-	-	overlaps another CDS with the same product name
HALMKLNM_01635	3.19e-61	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
HALMKLNM_01637	1.48e-25	recD2_2	3.1.11.5	-	L	ko:K01144	-	ko00000,ko01000	PIF1-like helicase
HALMKLNM_01639	1.56e-88	-	-	-	-	-	-	-	-
HALMKLNM_01640	6.26e-23	-	-	-	-	-	-	-	-
HALMKLNM_01641	8.2e-130	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HALMKLNM_01642	4.33e-112	-	-	-	S	-	-	-	hydrolase
HALMKLNM_01643	6.95e-261	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HALMKLNM_01644	1.42e-109	-	-	-	F	-	-	-	glutamine amidotransferase
HALMKLNM_01645	3.61e-32	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HALMKLNM_01646	1.19e-57	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HALMKLNM_01647	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HALMKLNM_01650	1.54e-253	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HALMKLNM_01651	9.6e-241	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HALMKLNM_01652	5.02e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HALMKLNM_01653	4.53e-79	-	-	-	-	-	-	-	-
HALMKLNM_01654	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HALMKLNM_01656	1.17e-98	-	-	-	S	-	-	-	Cell surface protein
HALMKLNM_01658	1.01e-229	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HALMKLNM_01659	1.54e-81	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
HALMKLNM_01660	1.63e-224	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HALMKLNM_01661	6.93e-280	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HALMKLNM_01662	8.61e-40	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HALMKLNM_01663	1.53e-181	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HALMKLNM_01665	2.48e-64	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HALMKLNM_01666	6.44e-117	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HALMKLNM_01667	6.95e-198	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
HALMKLNM_01668	7.32e-56	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HALMKLNM_01669	2.52e-76	-	-	-	-	-	-	-	-
HALMKLNM_01670	8.1e-53	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HALMKLNM_01671	3.84e-31	-	-	-	S	-	-	-	Cytochrome B5
HALMKLNM_01673	2.57e-78	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HALMKLNM_01674	1.48e-240	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HALMKLNM_01675	9.74e-126	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HALMKLNM_01676	1e-135	yueF	-	-	S	-	-	-	AI-2E family transporter
HALMKLNM_01677	3.8e-201	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HALMKLNM_01678	1.22e-147	tagH	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HALMKLNM_01679	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HALMKLNM_01680	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
HALMKLNM_01681	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HALMKLNM_01682	2.26e-139	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HALMKLNM_01683	4.34e-225	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HALMKLNM_01684	1.26e-207	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HALMKLNM_01685	4.92e-252	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HALMKLNM_01686	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HALMKLNM_01687	2.2e-129	-	-	-	G	-	-	-	MucBP domain
HALMKLNM_01688	3.55e-31	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
HALMKLNM_01689	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HALMKLNM_01690	1.5e-22	-	-	-	-	-	-	-	-
HALMKLNM_01691	5.69e-49	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HALMKLNM_01692	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HALMKLNM_01693	1.8e-203	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HALMKLNM_01694	1.84e-163	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HALMKLNM_01695	1.02e-164	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HALMKLNM_01696	3.45e-36	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HALMKLNM_01697	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HALMKLNM_01700	3.46e-39	-	-	-	S	-	-	-	Belongs to the HesB IscA family
HALMKLNM_01701	2.09e-70	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
HALMKLNM_01703	7.07e-67	-	-	-	K	-	-	-	LysR substrate binding domain
HALMKLNM_01704	1.01e-153	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HALMKLNM_01705	2.06e-253	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
HALMKLNM_01706	3.1e-137	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HALMKLNM_01707	8.2e-65	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HALMKLNM_01708	2.29e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HALMKLNM_01709	1.1e-257	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HALMKLNM_01710	1.81e-201	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HALMKLNM_01711	4.51e-27	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
HALMKLNM_01712	5.91e-194	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HALMKLNM_01713	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HALMKLNM_01714	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HALMKLNM_01715	7.37e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HALMKLNM_01716	1.6e-82	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HALMKLNM_01717	3.82e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HALMKLNM_01718	1.23e-139	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HALMKLNM_01719	2.32e-148	-	-	-	S	-	-	-	Glycosyl transferase family 2
HALMKLNM_01720	7.91e-82	-	-	-	D	-	-	-	peptidase
HALMKLNM_01721	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HALMKLNM_01722	1.42e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HALMKLNM_01723	5.27e-53	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HALMKLNM_01724	1.87e-306	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HALMKLNM_01725	3.53e-22	yneR	-	-	-	-	-	-	-
HALMKLNM_01726	9.72e-288	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HALMKLNM_01727	5.08e-282	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HALMKLNM_01728	1.35e-135	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HALMKLNM_01729	1.11e-193	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HALMKLNM_01730	1.56e-11	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HALMKLNM_01731	2.56e-140	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HALMKLNM_01732	1.82e-78	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
HALMKLNM_01733	3.34e-142	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
HALMKLNM_01734	1.89e-63	-	-	-	K	-	-	-	FCD domain
HALMKLNM_01735	1.43e-258	uxuB	1.1.1.57	-	G	ko:K00040	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase C-terminal domain
HALMKLNM_01736	2.87e-217	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
HALMKLNM_01737	2.6e-176	tdh	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HALMKLNM_01738	1.42e-217	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
HALMKLNM_01739	1.13e-75	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HALMKLNM_01740	8.05e-31	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HALMKLNM_01741	1.86e-212	-	-	-	S	-	-	-	Putative threonine/serine exporter
HALMKLNM_01742	2.55e-89	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HALMKLNM_01743	9.44e-121	yicL	-	-	EG	-	-	-	EamA-like transporter family
HALMKLNM_01744	9.67e-280	pepF	-	-	E	-	-	-	Oligopeptidase F
HALMKLNM_01745	3.68e-133	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HALMKLNM_01746	4.93e-225	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HALMKLNM_01747	1.78e-172	-	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
HALMKLNM_01748	1.02e-80	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HALMKLNM_01749	1.12e-218	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HALMKLNM_01750	2.33e-41	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HALMKLNM_01751	2.65e-270	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HALMKLNM_01752	6.08e-284	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
HALMKLNM_01753	3.33e-134	yxeH	-	-	S	-	-	-	hydrolase
HALMKLNM_01754	2.43e-151	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HALMKLNM_01755	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HALMKLNM_01756	2.49e-126	yycH	-	-	S	-	-	-	YycH protein
HALMKLNM_01757	3.35e-100	yycI	-	-	S	-	-	-	YycH protein
HALMKLNM_01758	1.37e-40	-	-	-	S	-	-	-	YjbR
HALMKLNM_01759	1.46e-147	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HALMKLNM_01760	4.68e-187	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HALMKLNM_01761	4.56e-93	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HALMKLNM_01762	2.75e-260	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	glycerol-3-phosphate transporter
HALMKLNM_01763	1.77e-170	-	-	-	S	-	-	-	interspecies interaction between organisms
HALMKLNM_01767	1.38e-165	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HALMKLNM_01768	3.77e-235	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HALMKLNM_01769	1.94e-199	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HALMKLNM_01770	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HALMKLNM_01771	2.47e-151	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HALMKLNM_01773	6.91e-73	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HALMKLNM_01774	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HALMKLNM_01775	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HALMKLNM_01776	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HALMKLNM_01777	7.37e-31	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HALMKLNM_01778	2.95e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HALMKLNM_01779	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HALMKLNM_01780	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HALMKLNM_01781	1.63e-117	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HALMKLNM_01782	5.56e-106	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HALMKLNM_01783	8.14e-144	vanR	-	-	K	-	-	-	response regulator
HALMKLNM_01784	5.29e-191	hpk31	-	-	T	-	-	-	Histidine kinase
HALMKLNM_01785	3.9e-111	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HALMKLNM_01786	2.38e-189	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HALMKLNM_01787	6.98e-179	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HALMKLNM_01788	2.75e-82	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HALMKLNM_01789	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HALMKLNM_01790	2.51e-43	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HALMKLNM_01791	1.87e-279	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HALMKLNM_01792	6.79e-317	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HALMKLNM_01793	1.29e-11	-	-	-	-	-	-	-	-
HALMKLNM_01794	1.85e-59	yyaT	-	-	K	ko:K02348	-	ko00000	protein acetylation
HALMKLNM_01795	6.92e-25	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
HALMKLNM_01796	5.02e-70	ymdB	-	-	L	-	-	-	phosphatase homologous to the C-terminal domain of histone macroH2A1
HALMKLNM_01797	1.63e-94	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HALMKLNM_01798	1.77e-155	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HALMKLNM_01800	0.0	-	-	-	L	-	-	-	DNA helicase
HALMKLNM_01801	3.9e-160	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HALMKLNM_01802	2.82e-217	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HALMKLNM_01803	2.78e-129	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HALMKLNM_01804	1.19e-105	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HALMKLNM_01805	2.76e-132	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HALMKLNM_01806	1.91e-40	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HALMKLNM_01807	1.49e-54	-	-	-	ET	-	-	-	Bacterial extracellular solute-binding proteins, family 3
HALMKLNM_01808	1.77e-189	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HALMKLNM_01809	3.22e-162	-	-	-	-	-	-	-	-
HALMKLNM_01810	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HALMKLNM_01811	9.88e-131	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HALMKLNM_01812	1.98e-111	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HALMKLNM_01813	5.37e-169	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HALMKLNM_01814	1.9e-31	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HALMKLNM_01815	6.28e-27	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HALMKLNM_01816	1.74e-75	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HALMKLNM_01817	1.82e-169	arcT	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
HALMKLNM_01818	5.91e-61	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HALMKLNM_01819	3.59e-148	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HALMKLNM_01820	2.59e-194	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HALMKLNM_01821	1.93e-253	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HALMKLNM_01822	1.37e-249	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HALMKLNM_01823	4.71e-188	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HALMKLNM_01824	1.1e-158	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HALMKLNM_01825	8.86e-140	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC