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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
ICKIEFNC_00002	4.29e-260	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
ICKIEFNC_00005	3.02e-115	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ICKIEFNC_00006	9.25e-124	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
ICKIEFNC_00007	9.98e-115	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
ICKIEFNC_00008	1.26e-306	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ICKIEFNC_00009	1.08e-164	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
ICKIEFNC_00010	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
ICKIEFNC_00011	3.25e-54	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
ICKIEFNC_00013	1.87e-148	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ICKIEFNC_00014	2.87e-161	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
ICKIEFNC_00015	4.1e-109	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ICKIEFNC_00016	2.56e-45	-	-	-	S	-	-	-	Enterocin A Immunity
ICKIEFNC_00017	7.36e-281	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
ICKIEFNC_00018	5.52e-24	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
ICKIEFNC_00019	4.81e-95	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
ICKIEFNC_00020	8e-284	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ICKIEFNC_00021	1.38e-195	yacL	-	-	S	-	-	-	domain protein
ICKIEFNC_00022	8.6e-312	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ICKIEFNC_00023	1.59e-263	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
ICKIEFNC_00024	1.71e-73	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ICKIEFNC_00025	1.32e-138	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICKIEFNC_00026	1.93e-92	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
ICKIEFNC_00027	3.2e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
ICKIEFNC_00028	3.08e-16	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
ICKIEFNC_00029	3.13e-109	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
ICKIEFNC_00030	2.58e-88	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ICKIEFNC_00031	9.98e-150	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
ICKIEFNC_00032	3.15e-97	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ICKIEFNC_00033	1.79e-63	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
ICKIEFNC_00034	4.43e-72	-	-	-	-	-	-	-	-
ICKIEFNC_00035	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ICKIEFNC_00036	1.1e-203	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICKIEFNC_00037	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICKIEFNC_00038	1.81e-58	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
ICKIEFNC_00039	1.36e-37	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
ICKIEFNC_00040	1.11e-96	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
ICKIEFNC_00041	2.23e-80	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
ICKIEFNC_00042	1.16e-269	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ICKIEFNC_00043	3.8e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ICKIEFNC_00044	6.62e-126	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ICKIEFNC_00045	2.93e-39	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
ICKIEFNC_00046	3.09e-83	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ICKIEFNC_00047	1.19e-105	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
ICKIEFNC_00048	3.85e-52	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
ICKIEFNC_00049	1.05e-132	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ICKIEFNC_00050	3.47e-104	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
ICKIEFNC_00051	2.82e-178	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
ICKIEFNC_00052	3.01e-87	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
ICKIEFNC_00053	2.77e-29	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
ICKIEFNC_00054	4.83e-204	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ICKIEFNC_00055	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
ICKIEFNC_00056	5.32e-127	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ICKIEFNC_00057	1.28e-39	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
ICKIEFNC_00058	1.7e-46	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ICKIEFNC_00059	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
ICKIEFNC_00060	0.0	-	-	-	P	ko:K12952	-	ko00000,ko01000	COG COG0474 Cation transport ATPase
ICKIEFNC_00061	0.0	ydaO	-	-	E	-	-	-	amino acid
ICKIEFNC_00062	3.75e-200	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
ICKIEFNC_00063	1.51e-159	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
ICKIEFNC_00064	1.13e-68	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
ICKIEFNC_00065	1.74e-105	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ICKIEFNC_00066	1.57e-118	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
ICKIEFNC_00067	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
ICKIEFNC_00068	1.31e-206	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ICKIEFNC_00069	1.4e-80	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
ICKIEFNC_00070	2.41e-109	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
ICKIEFNC_00071	9.27e-105	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
ICKIEFNC_00072	1.02e-10	-	-	-	K	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
ICKIEFNC_00073	3.44e-35	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
ICKIEFNC_00074	4.12e-168	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ICKIEFNC_00075	2.37e-142	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ICKIEFNC_00076	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
ICKIEFNC_00077	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
ICKIEFNC_00078	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
ICKIEFNC_00079	1.23e-107	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
ICKIEFNC_00080	7.97e-102	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
ICKIEFNC_00081	7.15e-161	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
ICKIEFNC_00082	4.52e-195	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
ICKIEFNC_00083	2.05e-191	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
ICKIEFNC_00084	2.07e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
ICKIEFNC_00086	6.46e-174	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
ICKIEFNC_00087	1.19e-231	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
ICKIEFNC_00088	6.65e-263	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
ICKIEFNC_00089	9.95e-165	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
ICKIEFNC_00090	4.33e-298	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
ICKIEFNC_00091	2.02e-167	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ICKIEFNC_00092	1.6e-133	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
ICKIEFNC_00093	5.67e-212	yclK	-	-	T	-	-	-	Histidine kinase
ICKIEFNC_00094	1.09e-188	-	-	-	E	-	-	-	Major Facilitator Superfamily
ICKIEFNC_00095	3.63e-223	eriC	-	-	P	ko:K03281	-	ko00000	chloride
ICKIEFNC_00096	1.19e-32	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
ICKIEFNC_00097	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
ICKIEFNC_00098	4.3e-91	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
ICKIEFNC_00099	1.37e-53	-	-	-	-	-	-	-	-
ICKIEFNC_00100	6.82e-148	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
ICKIEFNC_00101	3.07e-134	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ICKIEFNC_00102	7.01e-181	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
ICKIEFNC_00103	1e-72	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
ICKIEFNC_00104	3.34e-90	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
ICKIEFNC_00105	4.95e-145	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
ICKIEFNC_00106	3.92e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
ICKIEFNC_00107	1.95e-162	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ICKIEFNC_00108	2.27e-87	ybbR	-	-	S	-	-	-	YbbR-like protein
ICKIEFNC_00109	1.57e-284	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ICKIEFNC_00110	1.12e-38	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
ICKIEFNC_00111	3.57e-162	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
ICKIEFNC_00112	1.73e-23	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
ICKIEFNC_00113	4.44e-10	llrE	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
ICKIEFNC_00114	3.41e-112	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
ICKIEFNC_00115	2.44e-250	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ICKIEFNC_00116	9.29e-207	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ICKIEFNC_00117	1.44e-83	-	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
ICKIEFNC_00118	3.52e-125	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
ICKIEFNC_00119	2.62e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
ICKIEFNC_00120	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
ICKIEFNC_00121	7.37e-137	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
ICKIEFNC_00122	1.12e-185	ymfH	-	-	S	-	-	-	Peptidase M16
ICKIEFNC_00123	1.82e-116	ymfI	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
ICKIEFNC_00124	2.92e-84	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
ICKIEFNC_00125	1.41e-109	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ICKIEFNC_00126	1.84e-203	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ICKIEFNC_00127	1.02e-254	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
ICKIEFNC_00128	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ICKIEFNC_00129	2.83e-287	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ICKIEFNC_00130	1.08e-91	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
ICKIEFNC_00131	4.14e-193	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
ICKIEFNC_00132	1.66e-230	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ICKIEFNC_00133	1.46e-263	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
ICKIEFNC_00134	3.02e-20	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
ICKIEFNC_00136	3.61e-79	uspA3	-	-	T	-	-	-	universal stress protein
ICKIEFNC_00138	2.92e-264	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
ICKIEFNC_00139	2.04e-149	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
ICKIEFNC_00140	1.16e-309	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
ICKIEFNC_00141	3.61e-84	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
ICKIEFNC_00142	7.45e-182	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ICKIEFNC_00143	3.5e-18	-	-	-	-	-	-	-	-
ICKIEFNC_00144	3.08e-154	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
ICKIEFNC_00145	3.02e-236	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
ICKIEFNC_00146	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ICKIEFNC_00147	2.44e-49	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
ICKIEFNC_00148	1.83e-77	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ICKIEFNC_00149	4.23e-44	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
ICKIEFNC_00150	3.67e-17	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ICKIEFNC_00151	8.48e-19	cvpA	-	-	S	-	-	-	Colicin V production protein
ICKIEFNC_00152	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
ICKIEFNC_00153	5.23e-54	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
ICKIEFNC_00154	3.55e-79	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
ICKIEFNC_00155	4.2e-92	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ICKIEFNC_00156	1.2e-51	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
ICKIEFNC_00159	1.21e-178	-	1.1.1.29	-	C	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICKIEFNC_00160	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
ICKIEFNC_00161	1.65e-272	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ICKIEFNC_00162	7.25e-255	oatA	-	-	I	-	-	-	Acyltransferase
ICKIEFNC_00163	1.68e-22	-	-	-	-	-	-	-	-
ICKIEFNC_00165	1.44e-177	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
ICKIEFNC_00166	6.81e-128	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
ICKIEFNC_00167	1.34e-265	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
ICKIEFNC_00168	1.28e-103	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ICKIEFNC_00169	0.0	-	-	-	S	-	-	-	membrane
ICKIEFNC_00170	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
ICKIEFNC_00171	7.22e-07	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
ICKIEFNC_00172	2.07e-58	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
ICKIEFNC_00175	3.96e-156	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
ICKIEFNC_00176	4.24e-252	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
ICKIEFNC_00177	2.81e-68	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
ICKIEFNC_00178	6.35e-97	uspA	-	-	T	-	-	-	universal stress protein
ICKIEFNC_00180	2.58e-244	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
ICKIEFNC_00181	5.85e-31	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
ICKIEFNC_00182	5.9e-130	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ICKIEFNC_00183	3.66e-72	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
ICKIEFNC_00184	3.75e-222	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ICKIEFNC_00185	1.45e-204	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
ICKIEFNC_00186	2.9e-248	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ICKIEFNC_00187	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
ICKIEFNC_00188	6.92e-169	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
ICKIEFNC_00189	2.27e-102	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
ICKIEFNC_00190	1.96e-29	-	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
ICKIEFNC_00191	2.35e-207	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
ICKIEFNC_00192	1.64e-121	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
ICKIEFNC_00193	1.33e-70	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
ICKIEFNC_00194	8.33e-97	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
ICKIEFNC_00195	1.13e-162	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
ICKIEFNC_00196	3.02e-122	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
ICKIEFNC_00197	2.01e-115	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
ICKIEFNC_00198	6.52e-138	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
ICKIEFNC_00199	1.59e-124	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
ICKIEFNC_00200	1.16e-05	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
ICKIEFNC_00201	5.43e-196	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
ICKIEFNC_00203	2.65e-82	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
ICKIEFNC_00204	1.28e-180	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
ICKIEFNC_00205	1.05e-13	ftsL	-	-	D	-	-	-	Essential cell division protein
ICKIEFNC_00206	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
ICKIEFNC_00207	3.64e-172	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ICKIEFNC_00208	2.09e-233	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ICKIEFNC_00209	8.63e-195	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ICKIEFNC_00210	2.27e-76	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
ICKIEFNC_00211	4.06e-238	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
ICKIEFNC_00212	1.5e-227	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ICKIEFNC_00213	8.14e-43	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
ICKIEFNC_00214	8.19e-27	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
ICKIEFNC_00215	1.4e-104	ylmH	-	-	S	-	-	-	S4 domain protein
ICKIEFNC_00216	3.98e-92	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
ICKIEFNC_00217	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ICKIEFNC_00218	3.7e-130	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ICKIEFNC_00219	2e-91	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
ICKIEFNC_00221	5.22e-109	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
ICKIEFNC_00222	1.37e-116	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
ICKIEFNC_00223	2.83e-66	-	-	-	M	-	-	-	LysM domain protein
ICKIEFNC_00224	5.6e-25	-	-	-	P	-	-	-	Rhodanese Homology Domain
ICKIEFNC_00225	4.09e-52	-	-	-	M	-	-	-	LysM domain
ICKIEFNC_00226	1.34e-202	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
ICKIEFNC_00227	4.3e-243	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
ICKIEFNC_00228	5.29e-178	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
ICKIEFNC_00229	1.09e-253	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
ICKIEFNC_00230	4.26e-277	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
ICKIEFNC_00231	4.59e-121	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
ICKIEFNC_00232	7e-134	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
ICKIEFNC_00233	5.9e-195	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
ICKIEFNC_00234	1.84e-183	pbuO_1	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
ICKIEFNC_00235	1.87e-48	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
ICKIEFNC_00236	1.74e-34	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ICKIEFNC_00237	2.13e-103	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ICKIEFNC_00238	1.54e-236	-	-	-	-	-	-	-	-
ICKIEFNC_00239	5.19e-257	-	-	-	S	-	-	-	Protein conserved in bacteria
ICKIEFNC_00240	4.05e-254	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
ICKIEFNC_00241	0.0	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
ICKIEFNC_00242	1.32e-152	-	-	-	T	-	-	-	diguanylate cyclase activity
ICKIEFNC_00243	6.02e-37	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
ICKIEFNC_00244	2.41e-65	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
ICKIEFNC_00245	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
ICKIEFNC_00246	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
ICKIEFNC_00247	2.74e-69	-	-	-	S	-	-	-	Membrane
ICKIEFNC_00248	1.19e-79	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
ICKIEFNC_00250	3.73e-265	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
ICKIEFNC_00251	5.92e-33	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
ICKIEFNC_00252	1.55e-237	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
ICKIEFNC_00253	3.77e-79	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
ICKIEFNC_00254	2.89e-143	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
ICKIEFNC_00255	4.55e-105	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
ICKIEFNC_00256	8.26e-82	-	-	-	-	-	-	-	-
ICKIEFNC_00257	7.94e-224	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
ICKIEFNC_00258	1.44e-53	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
ICKIEFNC_00259	1.96e-60	-	-	-	M	-	-	-	Chain length determinant protein
ICKIEFNC_00260	1.41e-82	-	-	-	D	-	-	-	AAA domain
ICKIEFNC_00261	1.8e-106	capD	-	-	GM	-	-	-	CoA-binding domain
ICKIEFNC_00262	7.77e-157	-	-	-	GM	-	-	-	Polysaccharide biosynthesis protein
ICKIEFNC_00263	8.26e-208	epsN	-	-	M	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
ICKIEFNC_00264	4.04e-99	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
ICKIEFNC_00265	7.59e-36	-	-	-	S	ko:K19429	-	ko00000,ko01000	Bacterial transferase hexapeptide (six repeats)
ICKIEFNC_00266	1.48e-155	-	-	-	M	-	-	-	Glycosyl transferases group 1
ICKIEFNC_00267	1.13e-97	-	-	-	M	-	-	-	glycosyl transferase group 1
ICKIEFNC_00268	2.67e-06	-	-	-	M	-	-	-	glycosyl transferase group 1
ICKIEFNC_00269	5.01e-74	-	-	-	M	-	-	-	glycosyl transferase group 1
ICKIEFNC_00270	1.63e-89	-	-	-	M	-	-	-	Glycosyltransferase Family 4
ICKIEFNC_00271	2.03e-46	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyltransferase
ICKIEFNC_00272	1.42e-72	-	-	-	M	-	-	-	Glycosyltransferase like family 2
ICKIEFNC_00273	1.21e-08	-	-	-	S	-	-	-	EpsG family
ICKIEFNC_00274	5.39e-63	-	-	-	-	-	-	-	-
ICKIEFNC_00275	9.65e-147	-	-	-	S	-	-	-	Glycosyltransferase WbsX
ICKIEFNC_00276	9.65e-75	-	-	-	M	-	-	-	Glycosyl transferases group 1
ICKIEFNC_00277	2.39e-124	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
ICKIEFNC_00278	8.82e-183	-	5.1.3.6	-	GM	ko:K08679	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	RmlD substrate binding domain
ICKIEFNC_00279	1.17e-223	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ICKIEFNC_00280	1.45e-80	-	-	-	M	-	-	-	Glycosyl transferases group 1
ICKIEFNC_00281	2.66e-156	-	-	-	M	-	-	-	Glycosyl transferases group 1
ICKIEFNC_00284	9.5e-104	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
ICKIEFNC_00285	2.08e-52	ywnA	-	-	K	-	-	-	Transcriptional regulator
ICKIEFNC_00286	0.000676	-	-	-	S	-	-	-	CHY zinc finger
ICKIEFNC_00287	2.25e-85	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
ICKIEFNC_00289	3.23e-51	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
ICKIEFNC_00290	4.18e-30	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
ICKIEFNC_00292	5.21e-50	-	-	-	M	-	-	-	Acetyltransferase (GNAT) family
ICKIEFNC_00293	3.37e-81	-	-	-	H	-	-	-	Methyltransferase domain
ICKIEFNC_00300	2.13e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
ICKIEFNC_00301	4.44e-37	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
ICKIEFNC_00302	4.7e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
ICKIEFNC_00303	3.87e-21	-	-	-	-	-	-	-	-
ICKIEFNC_00306	7.88e-89	-	-	-	-	-	-	-	-
ICKIEFNC_00307	8.35e-126	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
ICKIEFNC_00308	1.28e-224	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
ICKIEFNC_00309	5.15e-155	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
ICKIEFNC_00310	4.03e-102	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ICKIEFNC_00311	6.04e-275	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ICKIEFNC_00312	6.85e-49	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ICKIEFNC_00313	2.77e-75	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ICKIEFNC_00314	3.83e-79	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ICKIEFNC_00315	1.14e-127	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
ICKIEFNC_00316	2.87e-76	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ICKIEFNC_00317	3.2e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF441)
ICKIEFNC_00318	2.63e-160	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
ICKIEFNC_00319	6.65e-143	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
ICKIEFNC_00320	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
ICKIEFNC_00321	1.17e-98	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
ICKIEFNC_00322	6.48e-67	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
ICKIEFNC_00323	6.87e-158	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
ICKIEFNC_00324	2.77e-84	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
ICKIEFNC_00325	1.6e-243	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
ICKIEFNC_00327	1.12e-91	-	-	-	M	-	-	-	GNAT acetyltransferase
ICKIEFNC_00328	1.34e-86	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
ICKIEFNC_00329	6.25e-72	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
ICKIEFNC_00330	3.97e-102	-	-	-	F	-	-	-	Hydrolase, nudix family
ICKIEFNC_00332	1.5e-87	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICKIEFNC_00333	1.33e-135	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
ICKIEFNC_00334	5.52e-45	-	-	-	K	-	-	-	Transcriptional regulator
ICKIEFNC_00335	1.94e-64	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
ICKIEFNC_00336	1.12e-213	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
ICKIEFNC_00337	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
ICKIEFNC_00338	1.03e-262	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
ICKIEFNC_00339	7.63e-237	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
ICKIEFNC_00341	1.27e-111	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ICKIEFNC_00342	3.3e-52	-	-	-	-	-	-	-	-
ICKIEFNC_00343	1.97e-152	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
ICKIEFNC_00344	1.7e-59	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
ICKIEFNC_00345	3.6e-276	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
ICKIEFNC_00346	3.38e-78	-	-	-	S	-	-	-	Helix-turn-helix domain
ICKIEFNC_00347	2e-157	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
ICKIEFNC_00348	1.1e-25	-	-	-	M	-	-	-	Lysin motif
ICKIEFNC_00349	2.4e-110	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
ICKIEFNC_00350	4.22e-106	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
ICKIEFNC_00351	2.52e-197	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
ICKIEFNC_00352	2.82e-87	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ICKIEFNC_00353	5.92e-40	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
ICKIEFNC_00354	4.63e-199	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ICKIEFNC_00355	3.85e-114	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
ICKIEFNC_00357	6.2e-276	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICKIEFNC_00358	7.87e-222	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
ICKIEFNC_00359	4.73e-40	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICKIEFNC_00360	1.71e-191	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ICKIEFNC_00361	2.35e-76	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphatase family
ICKIEFNC_00362	3.19e-220	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
ICKIEFNC_00363	1.66e-288	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
ICKIEFNC_00364	2.02e-48	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
ICKIEFNC_00366	2.83e-26	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
ICKIEFNC_00367	2.43e-142	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	Domain of unknown function (DUF4162)
ICKIEFNC_00368	1.51e-103	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type Na efflux pump, permease component
ICKIEFNC_00369	1.7e-120	-	-	-	EG	-	-	-	EamA-like transporter family
ICKIEFNC_00370	7.09e-99	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
ICKIEFNC_00371	3.72e-236	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ICKIEFNC_00372	9.73e-53	-	-	-	S	-	-	-	ASCH
ICKIEFNC_00373	1.3e-89	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase, peptidase S26
ICKIEFNC_00374	1.69e-147	-	-	-	S	-	-	-	EDD domain protein, DegV family
ICKIEFNC_00375	8.41e-52	-	-	-	K	-	-	-	Transcriptional regulator
ICKIEFNC_00376	6.26e-252	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
ICKIEFNC_00377	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ICKIEFNC_00378	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ICKIEFNC_00379	9.71e-107	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
ICKIEFNC_00380	6.49e-53	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
ICKIEFNC_00382	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
ICKIEFNC_00383	1.19e-211	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
ICKIEFNC_00384	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
ICKIEFNC_00385	6.47e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
ICKIEFNC_00386	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
ICKIEFNC_00387	5.64e-256	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
ICKIEFNC_00388	2.23e-53	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
ICKIEFNC_00389	2.01e-202	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
ICKIEFNC_00390	5.96e-118	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ICKIEFNC_00392	1.47e-105	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
ICKIEFNC_00393	4.86e-163	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ICKIEFNC_00394	2.21e-219	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
ICKIEFNC_00395	1.24e-173	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
ICKIEFNC_00396	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
ICKIEFNC_00397	3.14e-256	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
ICKIEFNC_00398	3.9e-190	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
ICKIEFNC_00399	2.44e-174	-	-	-	EG	-	-	-	EamA-like transporter family
ICKIEFNC_00400	8.41e-90	-	-	-	L	-	-	-	DNA alkylation repair enzyme
ICKIEFNC_00401	1.76e-232	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
ICKIEFNC_00402	6.65e-131	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ICKIEFNC_00403	1.96e-97	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
ICKIEFNC_00404	4.13e-185	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
ICKIEFNC_00407	2.15e-51	-	-	-	-	-	-	-	-
ICKIEFNC_00408	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
ICKIEFNC_00409	5.89e-34	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
ICKIEFNC_00410	3.11e-48	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
ICKIEFNC_00411	6.61e-219	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
ICKIEFNC_00412	3.6e-57	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
ICKIEFNC_00414	3.49e-111	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
ICKIEFNC_00415	2.98e-218	araT1	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
ICKIEFNC_00416	4.04e-148	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
ICKIEFNC_00417	7.65e-185	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
ICKIEFNC_00418	3.29e-173	-	-	-	K	-	-	-	Transcriptional regulator
ICKIEFNC_00419	5.8e-112	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ICKIEFNC_00420	1.06e-109	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
ICKIEFNC_00421	1.2e-236	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
ICKIEFNC_00422	3.69e-141	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
ICKIEFNC_00423	2.5e-255	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
ICKIEFNC_00424	2.49e-97	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ICKIEFNC_00425	1.69e-164	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
ICKIEFNC_00426	9.43e-57	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ICKIEFNC_00427	3.62e-72	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
ICKIEFNC_00428	7.24e-71	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
ICKIEFNC_00429	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ICKIEFNC_00430	7.53e-98	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
ICKIEFNC_00431	5.35e-150	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
ICKIEFNC_00432	8.52e-55	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
ICKIEFNC_00433	8.71e-184	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
ICKIEFNC_00434	2.54e-15	-	-	-	-	-	-	-	-
ICKIEFNC_00435	2e-88	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ICKIEFNC_00436	4.31e-127	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
ICKIEFNC_00437	1.15e-163	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ICKIEFNC_00438	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ICKIEFNC_00439	7.45e-220	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ICKIEFNC_00440	2.8e-56	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
ICKIEFNC_00441	2.77e-88	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
ICKIEFNC_00442	2.32e-109	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICKIEFNC_00445	8.63e-20	-	-	-	-	-	-	-	-
ICKIEFNC_00447	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
ICKIEFNC_00448	1.19e-53	-	-	-	S	-	-	-	repeat protein
ICKIEFNC_00449	2.93e-129	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
ICKIEFNC_00450	1.44e-87	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
ICKIEFNC_00451	1.48e-41	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ICKIEFNC_00452	5.47e-110	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ICKIEFNC_00453	3.21e-85	csm5	-	-	L	ko:K19140	-	ko00000,ko02048	RAMP superfamily
ICKIEFNC_00454	2.03e-78	-	-	-	L	ko:K19139	-	ko00000,ko02048	CRISPR-associated RAMP protein, Csm4 family
ICKIEFNC_00455	3.82e-88	csm3	-	-	L	ko:K09002	-	ko00000,ko02048	RAMP superfamily
ICKIEFNC_00456	8.49e-37	-	-	-	L	ko:K19138	-	ko00000,ko02048	Pfam:DUF310
ICKIEFNC_00457	2.35e-249	csm1	-	-	S	ko:K07016	-	ko00000,ko02048	CRISPR-associated protein Csm1 family
ICKIEFNC_00458	1.54e-36	cas6	-	-	S	-	-	-	CRISPR-associated endoribonuclease Cas6
ICKIEFNC_00459	2.33e-257	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
ICKIEFNC_00460	2.46e-265	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ICKIEFNC_00461	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ICKIEFNC_00462	2.09e-108	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
ICKIEFNC_00463	1.67e-123	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ICKIEFNC_00464	1.79e-170	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ICKIEFNC_00465	1.77e-33	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
ICKIEFNC_00466	9.8e-70	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
ICKIEFNC_00467	2.64e-100	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
ICKIEFNC_00469	3.71e-142	ydhF	-	-	S	-	-	-	Aldo keto reductase
ICKIEFNC_00470	1.83e-31	-	-	-	K	-	-	-	regulatory protein
ICKIEFNC_00471	1.99e-168	-	-	-	C	-	-	-	Aldo keto reductase
ICKIEFNC_00472	6.15e-73	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ICKIEFNC_00473	4.75e-201	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ICKIEFNC_00474	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
ICKIEFNC_00475	1.18e-166	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ICKIEFNC_00476	5.3e-136	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
ICKIEFNC_00477	2.69e-142	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ICKIEFNC_00478	1.91e-87	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
ICKIEFNC_00480	1.87e-75	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
ICKIEFNC_00481	5.93e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
ICKIEFNC_00482	2.08e-148	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
ICKIEFNC_00485	1.53e-126	-	-	-	M	-	-	-	Glycosyltransferase like family 2
ICKIEFNC_00486	1.72e-110	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
ICKIEFNC_00487	6.79e-116	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
ICKIEFNC_00488	4.35e-160	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ICKIEFNC_00489	6.01e-100	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ICKIEFNC_00490	2.09e-106	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ICKIEFNC_00491	2.55e-72	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
ICKIEFNC_00492	4.9e-300	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
ICKIEFNC_00493	1.22e-178	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
ICKIEFNC_00494	1.79e-44	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
ICKIEFNC_00495	3.15e-271	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
ICKIEFNC_00496	5.19e-119	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
ICKIEFNC_00497	5.1e-156	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
ICKIEFNC_00498	6.58e-172	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
ICKIEFNC_00499	1.42e-143	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
ICKIEFNC_00500	8.38e-133	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
ICKIEFNC_00501	1.24e-186	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
ICKIEFNC_00502	1.71e-90	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
ICKIEFNC_00503	1.68e-61	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
ICKIEFNC_00504	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
ICKIEFNC_00505	1.61e-73	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
ICKIEFNC_00506	1.4e-27	-	-	-	-	-	-	-	-
ICKIEFNC_00508	1.82e-156	-	-	-	K	-	-	-	LysR substrate binding domain
ICKIEFNC_00509	1.38e-242	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICKIEFNC_00510	5.56e-138	-	-	-	S	-	-	-	Acyltransferase family
ICKIEFNC_00511	1.19e-203	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
ICKIEFNC_00512	3.31e-292	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
ICKIEFNC_00513	6.95e-96	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ICKIEFNC_00514	9.88e-175	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
ICKIEFNC_00515	3.04e-283	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ICKIEFNC_00516	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICKIEFNC_00517	1.37e-131	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICKIEFNC_00518	9.14e-41	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICKIEFNC_00519	8.62e-123	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
ICKIEFNC_00520	7.34e-167	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
ICKIEFNC_00521	3.35e-65	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ICKIEFNC_00522	5.02e-94	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
ICKIEFNC_00523	2.86e-24	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
ICKIEFNC_00524	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ICKIEFNC_00525	8.72e-126	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
ICKIEFNC_00526	9.75e-188	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
ICKIEFNC_00527	7.81e-147	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
ICKIEFNC_00528	3.81e-188	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
ICKIEFNC_00529	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
ICKIEFNC_00530	6.09e-96	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
ICKIEFNC_00531	3.57e-33	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
ICKIEFNC_00532	1.76e-20	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily
ICKIEFNC_00533	7.87e-111	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
ICKIEFNC_00534	3.51e-33	-	-	-	-	-	-	-	-
ICKIEFNC_00535	1.47e-30	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
ICKIEFNC_00536	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ICKIEFNC_00537	3.69e-313	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ICKIEFNC_00538	3.67e-251	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ICKIEFNC_00539	6.79e-246	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
ICKIEFNC_00540	6.83e-274	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ICKIEFNC_00541	3.51e-05	-	-	-	S	-	-	-	Tetratricopeptide repeat
ICKIEFNC_00542	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ICKIEFNC_00543	2.18e-146	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ICKIEFNC_00544	2.6e-53	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ICKIEFNC_00545	1.33e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
ICKIEFNC_00546	2.49e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
ICKIEFNC_00547	2.16e-251	-	-	-	E	ko:K03294	-	ko00000	amino acid
ICKIEFNC_00548	2.19e-78	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
ICKIEFNC_00549	2.74e-145	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
ICKIEFNC_00550	1.6e-74	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ICKIEFNC_00551	1.99e-37	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
ICKIEFNC_00552	1.32e-55	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
ICKIEFNC_00553	9.04e-263	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ICKIEFNC_00554	6.15e-53	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ICKIEFNC_00555	4.55e-187	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ICKIEFNC_00556	6.55e-295	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
ICKIEFNC_00557	7.23e-130	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
ICKIEFNC_00558	6.84e-35	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICKIEFNC_00559	2.54e-179	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
ICKIEFNC_00560	3.63e-304	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ICKIEFNC_00561	8.54e-303	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
ICKIEFNC_00562	7.35e-69	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
ICKIEFNC_00563	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
ICKIEFNC_00564	1.93e-74	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
ICKIEFNC_00565	3.76e-143	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
ICKIEFNC_00566	1.21e-239	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
ICKIEFNC_00567	1.11e-115	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
ICKIEFNC_00568	6.19e-193	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ICKIEFNC_00569	1.33e-178	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ICKIEFNC_00570	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ICKIEFNC_00571	5.34e-153	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ICKIEFNC_00572	8.22e-30	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
ICKIEFNC_00573	8.34e-132	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
ICKIEFNC_00574	1.89e-120	-	-	-	M	-	-	-	Phosphotransferase enzyme family
ICKIEFNC_00575	9.86e-36	spxA	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
ICKIEFNC_00576	6.32e-236	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
ICKIEFNC_00577	6.63e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
ICKIEFNC_00578	6.55e-36	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
ICKIEFNC_00579	1.63e-213	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
ICKIEFNC_00580	2.53e-261	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ICKIEFNC_00581	8.32e-21	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
ICKIEFNC_00582	6.22e-70	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
ICKIEFNC_00583	8.04e-313	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ICKIEFNC_00584	3.29e-181	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ICKIEFNC_00585	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ICKIEFNC_00586	2.82e-74	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ICKIEFNC_00587	2.96e-57	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ICKIEFNC_00588	1.39e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ICKIEFNC_00589	2.33e-124	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
ICKIEFNC_00590	2.18e-129	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ICKIEFNC_00591	1.9e-171	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
ICKIEFNC_00592	7.51e-114	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
ICKIEFNC_00593	1.47e-230	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ICKIEFNC_00594	1.96e-110	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
ICKIEFNC_00595	5.99e-277	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
ICKIEFNC_00596	1.89e-140	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
ICKIEFNC_00597	1.02e-138	ampC	-	-	V	-	-	-	Beta-lactamase
ICKIEFNC_00598	1.83e-41	-	-	-	-	-	-	-	-
ICKIEFNC_00599	7.44e-153	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
ICKIEFNC_00600	7.05e-257	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
ICKIEFNC_00602	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
ICKIEFNC_00603	5.74e-218	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
ICKIEFNC_00604	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
ICKIEFNC_00605	3.65e-75	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ICKIEFNC_00606	1.51e-165	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
ICKIEFNC_00607	1.02e-119	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
ICKIEFNC_00608	8.2e-152	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ICKIEFNC_00609	6.33e-74	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ICKIEFNC_00610	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ICKIEFNC_00611	3.59e-34	ylxQ	-	-	J	-	-	-	ribosomal protein
ICKIEFNC_00612	7.84e-52	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
ICKIEFNC_00613	8.77e-217	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
ICKIEFNC_00614	1.16e-85	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
ICKIEFNC_00615	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ICKIEFNC_00616	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
ICKIEFNC_00617	3.58e-196	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
ICKIEFNC_00618	7.84e-132	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
ICKIEFNC_00619	7.03e-135	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ICKIEFNC_00620	2.03e-105	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
ICKIEFNC_00621	1.02e-147	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
ICKIEFNC_00622	8.28e-64	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
ICKIEFNC_00623	4.32e-47	-	2.1.1.63	-	H	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ICKIEFNC_00625	3.28e-312	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
ICKIEFNC_00626	1.3e-59	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
ICKIEFNC_00627	3.84e-258	ynbB	-	-	P	-	-	-	aluminum resistance
ICKIEFNC_00628	1.42e-139	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ICKIEFNC_00629	6.17e-24	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
ICKIEFNC_00630	2.92e-60	yqhL	-	-	P	-	-	-	Rhodanese-like protein
ICKIEFNC_00631	8.22e-203	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
ICKIEFNC_00632	1.74e-34	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
ICKIEFNC_00633	2.12e-88	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
ICKIEFNC_00634	2.55e-49	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ICKIEFNC_00635	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
ICKIEFNC_00637	1.4e-87	yciQ	-	-	P	-	-	-	membrane protein (DUF2207)
ICKIEFNC_00638	1.78e-57	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
ICKIEFNC_00639	1.38e-119	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
ICKIEFNC_00640	3.28e-35	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
ICKIEFNC_00641	7.41e-41	ynzC	-	-	S	-	-	-	UPF0291 protein
ICKIEFNC_00642	6.38e-107	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ICKIEFNC_00643	5.46e-234	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
ICKIEFNC_00644	5.91e-65	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
ICKIEFNC_00645	5.17e-153	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
ICKIEFNC_00646	5.41e-105	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
ICKIEFNC_00647	1.44e-23	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ICKIEFNC_00648	1.15e-181	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ICKIEFNC_00649	3.32e-133	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ICKIEFNC_00650	1.45e-46	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ICKIEFNC_00651	8.06e-60	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
ICKIEFNC_00652	3.77e-123	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ICKIEFNC_00653	1.45e-48	-	-	-	S	-	-	-	Protein conserved in bacteria
ICKIEFNC_00654	1.14e-147	-	-	-	-	-	-	-	-
ICKIEFNC_00655	4.27e-143	-	-	-	-	-	-	-	-
ICKIEFNC_00656	4.1e-171	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
ICKIEFNC_00657	3.41e-24	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
ICKIEFNC_00658	1.58e-147	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ICKIEFNC_00659	6.25e-218	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
ICKIEFNC_00660	1.46e-141	csrR	-	-	K	-	-	-	response regulator
ICKIEFNC_00662	6.64e-137	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
ICKIEFNC_00663	5.1e-285	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ICKIEFNC_00664	5.19e-199	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ICKIEFNC_00665	6.6e-76	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ICKIEFNC_00666	2.32e-119	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
ICKIEFNC_00667	1.82e-49	-	-	-	-	-	-	-	-
ICKIEFNC_00668	2.97e-163	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ICKIEFNC_00669	4.91e-172	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
ICKIEFNC_00670	6.9e-37	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
ICKIEFNC_00671	4.86e-120	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
ICKIEFNC_00672	3.48e-114	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
ICKIEFNC_00673	8.93e-35	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
ICKIEFNC_00674	1.58e-73	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
ICKIEFNC_00675	1.14e-153	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
ICKIEFNC_00676	3.23e-104	-	-	-	H	-	-	-	Nodulation protein S (NodS)
ICKIEFNC_00677	2.79e-65	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
ICKIEFNC_00678	4.64e-89	yqeK	-	-	H	-	-	-	Hydrolase, HD family
ICKIEFNC_00679	7.07e-99	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ICKIEFNC_00680	9.56e-41	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
ICKIEFNC_00681	9.8e-228	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
ICKIEFNC_00682	1.92e-90	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
ICKIEFNC_00683	2.9e-68	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ICKIEFNC_00684	4.44e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
ICKIEFNC_00685	1.25e-102	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ICKIEFNC_00686	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ICKIEFNC_00687	2.83e-137	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
ICKIEFNC_00688	1.54e-93	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
ICKIEFNC_00689	1.04e-85	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ICKIEFNC_00690	3.05e-62	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ICKIEFNC_00691	1.21e-136	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
ICKIEFNC_00692	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ICKIEFNC_00693	1.16e-87	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
ICKIEFNC_00694	6.4e-80	phaJ	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
ICKIEFNC_00695	1.24e-282	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
ICKIEFNC_00696	4.9e-238	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
ICKIEFNC_00697	5e-97	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ICKIEFNC_00698	2.95e-59	ytpP	-	-	CO	-	-	-	Thioredoxin
ICKIEFNC_00700	2.35e-130	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
ICKIEFNC_00701	3.39e-125	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
ICKIEFNC_00702	1.12e-87	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
ICKIEFNC_00703	2.33e-121	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
ICKIEFNC_00704	1.1e-68	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
ICKIEFNC_00706	8.07e-144	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
ICKIEFNC_00707	2.66e-162	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
ICKIEFNC_00708	2.92e-28	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
ICKIEFNC_00709	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
ICKIEFNC_00711	4.59e-115	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
ICKIEFNC_00712	4.06e-224	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
ICKIEFNC_00713	3.44e-92	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
ICKIEFNC_00714	3.09e-59	ykuL	-	-	S	-	-	-	CBS domain
ICKIEFNC_00715	1.05e-152	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
ICKIEFNC_00716	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
ICKIEFNC_00717	2.1e-305	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
ICKIEFNC_00718	1.89e-291	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ICKIEFNC_00719	7.35e-140	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
ICKIEFNC_00720	4.96e-129	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
ICKIEFNC_00721	3.3e-160	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ICKIEFNC_00722	2.06e-274	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
ICKIEFNC_00723	4.61e-84	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
ICKIEFNC_00724	1.16e-60	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
ICKIEFNC_00725	4.97e-248	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
ICKIEFNC_00726	1.27e-124	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
ICKIEFNC_00727	1.04e-131	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
ICKIEFNC_00728	1.48e-36	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICKIEFNC_00729	2.12e-129	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ICKIEFNC_00730	1.29e-79	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
ICKIEFNC_00731	2.66e-86	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
ICKIEFNC_00732	1.78e-48	-	-	-	-	-	-	-	-
ICKIEFNC_00734	5.35e-243	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
ICKIEFNC_00735	8.94e-104	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ICKIEFNC_00736	1.48e-76	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
ICKIEFNC_00737	4.91e-244	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
ICKIEFNC_00738	6.58e-245	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
ICKIEFNC_00739	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
ICKIEFNC_00740	5.21e-226	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ICKIEFNC_00742	1.49e-223	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
ICKIEFNC_00743	7.47e-213	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
ICKIEFNC_00744	2.72e-230	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
ICKIEFNC_00745	2.52e-290	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
ICKIEFNC_00746	1.35e-186	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
ICKIEFNC_00747	1.25e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
ICKIEFNC_00748	1.96e-78	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
ICKIEFNC_00749	4.06e-16	-	-	-	-	-	-	-	-
ICKIEFNC_00750	3.81e-37	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
ICKIEFNC_00751	6.55e-280	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
ICKIEFNC_00752	8e-111	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
ICKIEFNC_00753	1.11e-190	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
ICKIEFNC_00754	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
ICKIEFNC_00755	2.85e-57	cps3F	-	-	-	-	-	-	-
ICKIEFNC_00756	1.28e-107	-	-	-	S	-	-	-	Membrane
ICKIEFNC_00757	0.0	-	-	-	E	-	-	-	Amino acid permease
ICKIEFNC_00758	3.6e-293	cadA	-	-	P	-	-	-	P-type ATPase
ICKIEFNC_00759	1.01e-145	degV	-	-	S	-	-	-	EDD domain protein, DegV family
ICKIEFNC_00760	6.83e-188	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
ICKIEFNC_00761	9.62e-69	-	-	-	F	-	-	-	glutamine amidotransferase
ICKIEFNC_00762	1.43e-35	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
ICKIEFNC_00763	6.07e-186	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ICKIEFNC_00764	2.77e-174	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
ICKIEFNC_00765	1.18e-103	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
ICKIEFNC_00766	1.34e-207	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
ICKIEFNC_00767	1.81e-19	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
ICKIEFNC_00768	5.74e-282	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
ICKIEFNC_00769	3.22e-157	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
ICKIEFNC_00770	1.39e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1634)
ICKIEFNC_00771	3.86e-154	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
ICKIEFNC_00772	1.91e-106	lysR5	-	-	K	-	-	-	LysR substrate binding domain
ICKIEFNC_00773	3.04e-71	lssY	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
ICKIEFNC_00774	2.9e-14	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ICKIEFNC_00775	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
ICKIEFNC_00776	1.59e-86	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
ICKIEFNC_00777	1.07e-307	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
ICKIEFNC_00778	1.6e-262	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ICKIEFNC_00782	1.78e-273	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
ICKIEFNC_00783	4.34e-61	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
ICKIEFNC_00784	1.32e-85	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
ICKIEFNC_00785	3.16e-284	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
ICKIEFNC_00786	1.43e-53	yjbH	-	-	Q	-	-	-	Thioredoxin
ICKIEFNC_00787	4.51e-125	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
ICKIEFNC_00788	5.19e-150	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
ICKIEFNC_00789	1.35e-154	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
ICKIEFNC_00790	7.48e-147	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ICKIEFNC_00791	6.43e-149	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ICKIEFNC_00792	3.2e-73	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
ICKIEFNC_00793	1.21e-188	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
ICKIEFNC_00794	1.39e-100	-	-	-	S	-	-	-	VIT family
ICKIEFNC_00795	2.71e-107	-	-	-	S	-	-	-	membrane
ICKIEFNC_00796	4.58e-52	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
ICKIEFNC_00797	8.68e-83	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
ICKIEFNC_00798	3.39e-47	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
ICKIEFNC_00799	1.39e-95	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ICKIEFNC_00801	2.23e-10	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ICKIEFNC_00803	9.17e-219	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
ICKIEFNC_00804	1.47e-201	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
ICKIEFNC_00805	2.76e-53	-	-	-	S	-	-	-	VanZ like family
ICKIEFNC_00806	4e-153	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
ICKIEFNC_00807	7.71e-128	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICKIEFNC_00808	3.19e-152	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
ICKIEFNC_00809	2.4e-123	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
ICKIEFNC_00810	2.51e-35	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
ICKIEFNC_00811	1.01e-17	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
ICKIEFNC_00815	7e-124	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
ICKIEFNC_00816	1.81e-238	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
ICKIEFNC_00817	9.2e-73	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
ICKIEFNC_00818	4.29e-77	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
ICKIEFNC_00819	4.82e-145	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
ICKIEFNC_00820	1.01e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
ICKIEFNC_00821	3.79e-118	dedA	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
ICKIEFNC_00822	9.36e-118	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
ICKIEFNC_00823	3.62e-65	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
ICKIEFNC_00824	2.44e-104	-	-	-	-	-	-	-	-
ICKIEFNC_00825	4.72e-66	-	-	-	L	-	-	-	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ICKIEFNC_00826	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
ICKIEFNC_00827	0.0	-	-	-	M	-	-	-	Cna protein B-type domain
ICKIEFNC_00828	7.64e-121	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
ICKIEFNC_00829	7.21e-169	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
ICKIEFNC_00830	4.18e-201	-	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
ICKIEFNC_00831	4.15e-192	-	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
ICKIEFNC_00832	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
ICKIEFNC_00833	1.56e-229	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
ICKIEFNC_00834	4.15e-313	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
ICKIEFNC_00835	2.09e-131	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
ICKIEFNC_00836	4.71e-137	-	-	-	-	-	-	-	-
ICKIEFNC_00837	5.69e-54	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
ICKIEFNC_00838	7.78e-47	-	-	-	-	-	-	-	-
ICKIEFNC_00839	8.88e-233	-	-	-	L	-	-	-	Probable transposase
ICKIEFNC_00841	3.13e-83	-	-	-	EGP	-	-	-	Major Facilitator
ICKIEFNC_00842	5.62e-132	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
ICKIEFNC_00843	2.15e-298	-	-	-	EGP	-	-	-	Major Facilitator
ICKIEFNC_00844	4.78e-91	-	-	-	H	-	-	-	ThiF family
ICKIEFNC_00845	7.84e-264	arsR	-	-	K	-	-	-	DNA-binding transcription factor activity
ICKIEFNC_00846	3.68e-124	-	-	-	K	-	-	-	Transcriptional regulator
ICKIEFNC_00847	3.54e-42	-	-	-	L	ko:K07483	-	ko00000	Transposase
ICKIEFNC_00848	1.04e-219	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
ICKIEFNC_00849	5.57e-80	-	-	-	V	-	-	-	HNH endonuclease
ICKIEFNC_00851	2.4e-41	-	-	-	L	-	-	-	MULE transposase domain
ICKIEFNC_00852	4.03e-63	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
ICKIEFNC_00853	1.43e-73	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
ICKIEFNC_00854	1.05e-188	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
ICKIEFNC_00855	4.18e-46	-	-	-	-	-	-	-	-
ICKIEFNC_00856	2.23e-216	repA	-	-	S	-	-	-	Replication initiator protein A
ICKIEFNC_00857	7.93e-170	-	-	-	S	-	-	-	Fic/DOC family
ICKIEFNC_00858	3.07e-53	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
ICKIEFNC_00859	1.99e-35	-	-	-	-	-	-	-	-
ICKIEFNC_00860	4.3e-158	-	-	-	S	-	-	-	protein conserved in bacteria
ICKIEFNC_00861	3.47e-54	-	-	-	-	-	-	-	-
ICKIEFNC_00862	1.92e-35	-	-	-	-	-	-	-	-
ICKIEFNC_00863	0.0	-	-	-	L	-	-	-	MobA MobL family protein
ICKIEFNC_00864	3.11e-249	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
ICKIEFNC_00865	4.12e-119	-	-	-	-	-	-	-	-
ICKIEFNC_00866	3.41e-168	-	-	-	F	-	-	-	NUDIX domain
ICKIEFNC_00867	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ICKIEFNC_00868	5.88e-132	pncA	-	-	Q	-	-	-	Isochorismatase family
ICKIEFNC_00869	1.82e-134	-	-	-	L	-	-	-	Helix-turn-helix domain
ICKIEFNC_00870	1.05e-142	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
ICKIEFNC_00871	1.19e-32	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ICKIEFNC_00872	9.8e-113	saeS	2.7.13.3	-	T	ko:K10681	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
ICKIEFNC_00873	1.24e-98	saeR	-	-	K	ko:K10682	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
ICKIEFNC_00875	3.12e-202	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
ICKIEFNC_00876	1.59e-15	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
ICKIEFNC_00877	1.46e-09	-	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
ICKIEFNC_00878	4.18e-75	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
ICKIEFNC_00879	7.92e-93	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
ICKIEFNC_00881	8.56e-50	-	-	-	K	-	-	-	SIR2-like domain
ICKIEFNC_00882	3.13e-25	-	-	-	-	-	-	-	-
ICKIEFNC_00898	1.38e-165	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
ICKIEFNC_00899	3.77e-235	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
ICKIEFNC_00900	1.94e-199	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
ICKIEFNC_00901	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
ICKIEFNC_00902	2.47e-151	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
ICKIEFNC_00904	6.91e-73	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
ICKIEFNC_00905	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
ICKIEFNC_00906	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICKIEFNC_00907	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICKIEFNC_00908	7.37e-31	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
ICKIEFNC_00909	2.95e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ICKIEFNC_00910	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
ICKIEFNC_00911	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ICKIEFNC_00912	1.63e-117	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
ICKIEFNC_00913	5.56e-106	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
ICKIEFNC_00914	8.14e-144	vanR	-	-	K	-	-	-	response regulator
ICKIEFNC_00915	1.85e-191	hpk31	-	-	T	-	-	-	Histidine kinase
ICKIEFNC_00916	3.9e-111	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
ICKIEFNC_00917	2.38e-189	-	-	-	G	-	-	-	Transporter, major facilitator family protein
ICKIEFNC_00918	2.05e-276	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ICKIEFNC_00919	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
ICKIEFNC_00920	2.84e-42	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ICKIEFNC_00921	1.08e-278	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
ICKIEFNC_00922	6.79e-317	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
ICKIEFNC_00923	1.29e-11	-	-	-	-	-	-	-	-
ICKIEFNC_00924	1.85e-59	yyaT	-	-	K	ko:K02348	-	ko00000	protein acetylation
ICKIEFNC_00925	1.56e-67	ymdB	-	-	L	-	-	-	phosphatase homologous to the C-terminal domain of histone macroH2A1
ICKIEFNC_00926	1.63e-94	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
ICKIEFNC_00927	1.25e-148	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
ICKIEFNC_00929	0.0	-	-	-	L	-	-	-	DNA helicase
ICKIEFNC_00930	3.9e-160	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ICKIEFNC_00931	2.82e-217	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
ICKIEFNC_00932	5.61e-129	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
ICKIEFNC_00933	1.19e-105	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
ICKIEFNC_00934	2.76e-132	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
ICKIEFNC_00935	1.91e-40	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ICKIEFNC_00936	1.49e-54	-	-	-	ET	-	-	-	Bacterial extracellular solute-binding proteins, family 3
ICKIEFNC_00937	1.77e-189	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
ICKIEFNC_00938	9.2e-162	-	-	-	-	-	-	-	-
ICKIEFNC_00939	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ICKIEFNC_00940	9.88e-131	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
ICKIEFNC_00941	4.87e-112	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ICKIEFNC_00942	5.37e-169	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
ICKIEFNC_00943	1.9e-31	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
ICKIEFNC_00944	1.9e-115	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
ICKIEFNC_00945	1.82e-169	arcT	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
ICKIEFNC_00946	5.91e-61	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
ICKIEFNC_00947	7.23e-148	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ICKIEFNC_00948	1.05e-193	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
ICKIEFNC_00949	3.23e-115	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
ICKIEFNC_00950	2.39e-42	-	-	-	S	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
ICKIEFNC_00951	1.13e-30	-	-	-	-	-	-	-	-
ICKIEFNC_00953	1.45e-18	-	-	-	S	-	-	-	Domain of unknown function (DUF4393)
ICKIEFNC_00954	2.16e-41	-	-	-	-	-	-	-	-
ICKIEFNC_00955	1.19e-32	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
ICKIEFNC_00958	1.53e-51	-	-	-	K	-	-	-	Peptidase S24-like
ICKIEFNC_00962	6.87e-22	-	-	-	-	-	-	-	-
ICKIEFNC_00964	3.1e-21	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
ICKIEFNC_00965	1.75e-19	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
ICKIEFNC_00966	2.68e-103	-	-	-	S	-	-	-	DNA binding
ICKIEFNC_00971	8.09e-68	-	-	-	S	-	-	-	Putative HNHc nuclease
ICKIEFNC_00972	6.52e-31	-	-	-	L	-	-	-	N-terminal phage replisome organiser (Phage_rep_org_N)
ICKIEFNC_00975	4.18e-28	-	-	-	-	-	-	-	-
ICKIEFNC_00976	5.72e-89	-	-	-	-	-	-	-	-
ICKIEFNC_00982	5.01e-28	-	-	-	-	-	-	-	-
ICKIEFNC_00984	1.76e-77	-	-	-	Q	-	-	-	DNA (cytosine-5-)-methyltransferase activity
ICKIEFNC_00988	9.84e-38	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
ICKIEFNC_00992	5.12e-92	-	-	-	L	-	-	-	HNH nucleases
ICKIEFNC_00993	6.88e-105	-	-	-	L	-	-	-	Phage terminase, small subunit
ICKIEFNC_00994	0.0	-	-	-	S	-	-	-	Phage Terminase
ICKIEFNC_00996	1.5e-244	-	-	-	S	-	-	-	Phage portal protein
ICKIEFNC_00997	1.63e-145	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
ICKIEFNC_00998	2.69e-246	-	-	-	S	-	-	-	Phage capsid family
ICKIEFNC_00999	2.18e-29	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
ICKIEFNC_01000	5.86e-65	-	-	-	S	-	-	-	Phage head-tail joining protein
ICKIEFNC_01001	4.62e-71	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
ICKIEFNC_01002	4.18e-75	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
ICKIEFNC_01003	2.5e-98	-	-	-	S	-	-	-	Phage tail tube protein
ICKIEFNC_01004	6.74e-25	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
ICKIEFNC_01006	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
ICKIEFNC_01007	1.77e-99	-	-	-	S	-	-	-	Phage tail protein
ICKIEFNC_01008	1.22e-146	rny	-	-	D	ko:K12088,ko:K18682	ko03018,ko05120,map03018,map05120	ko00000,ko00001,ko00002,ko01000,ko02044,ko03019	peptidase
ICKIEFNC_01010	1.09e-30	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
ICKIEFNC_01016	3.86e-14	-	-	-	S	-	-	-	Bacteriophage holin
ICKIEFNC_01017	1.96e-164	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
ICKIEFNC_01018	1.93e-253	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
ICKIEFNC_01019	1.37e-249	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
ICKIEFNC_01020	4.71e-188	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
ICKIEFNC_01021	1.1e-158	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICKIEFNC_01022	8.86e-140	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
ICKIEFNC_01023	5.67e-71	-	-	-	M	-	-	-	MucBP domain
ICKIEFNC_01024	6.82e-235	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ICKIEFNC_01025	5.96e-67	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
ICKIEFNC_01026	7.37e-175	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
ICKIEFNC_01027	6.83e-72	-	-	-	EGP	-	-	-	Transmembrane secretion effector
ICKIEFNC_01028	3.21e-256	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ICKIEFNC_01029	2.25e-216	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ICKIEFNC_01030	3.6e-26	rimL	1.1.1.25	-	J	ko:K00014,ko:K03817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ICKIEFNC_01032	1.17e-140	dkgB	-	-	S	-	-	-	reductase
ICKIEFNC_01033	5.45e-35	-	-	-	-	-	-	-	-
ICKIEFNC_01034	3.22e-98	-	-	-	F	-	-	-	Phosphorylase superfamily
ICKIEFNC_01035	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
ICKIEFNC_01036	6.98e-79	ytkL	-	-	S	-	-	-	Beta-lactamase superfamily domain
ICKIEFNC_01037	1e-123	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
ICKIEFNC_01038	9.11e-156	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
ICKIEFNC_01039	4.08e-111	-	-	-	S	-	-	-	overlaps another CDS with the same product name
ICKIEFNC_01041	1.66e-49	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
ICKIEFNC_01045	2.08e-14	recD2_2	3.1.11.5	-	L	ko:K01144	-	ko00000,ko01000	PIF1-like helicase
ICKIEFNC_01047	1.56e-88	-	-	-	-	-	-	-	-
ICKIEFNC_01048	6.26e-23	-	-	-	-	-	-	-	-
ICKIEFNC_01049	8.2e-130	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
ICKIEFNC_01050	4.33e-112	-	-	-	S	-	-	-	hydrolase
ICKIEFNC_01051	6.95e-261	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
ICKIEFNC_01052	1e-109	-	-	-	F	-	-	-	glutamine amidotransferase
ICKIEFNC_01053	3.61e-32	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
ICKIEFNC_01054	1.19e-57	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
ICKIEFNC_01055	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
ICKIEFNC_01058	1.54e-253	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ICKIEFNC_01059	9.6e-241	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ICKIEFNC_01060	5.02e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
ICKIEFNC_01061	4.53e-79	-	-	-	-	-	-	-	-
ICKIEFNC_01062	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
ICKIEFNC_01064	1.79e-98	-	-	-	S	-	-	-	Cell surface protein
ICKIEFNC_01066	1.01e-229	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
ICKIEFNC_01067	1.54e-81	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
ICKIEFNC_01068	1.63e-224	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
ICKIEFNC_01069	6.93e-280	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
ICKIEFNC_01070	8.61e-40	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
ICKIEFNC_01071	1.53e-181	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ICKIEFNC_01073	2.48e-64	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
ICKIEFNC_01074	6.44e-117	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
ICKIEFNC_01075	6.95e-198	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
ICKIEFNC_01076	7.32e-56	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
ICKIEFNC_01077	2.52e-76	-	-	-	-	-	-	-	-
ICKIEFNC_01078	8.1e-53	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
ICKIEFNC_01079	3.84e-31	-	-	-	S	-	-	-	Cytochrome B5
ICKIEFNC_01081	2.57e-78	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
ICKIEFNC_01082	1.48e-240	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICKIEFNC_01083	9.74e-126	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
ICKIEFNC_01084	1e-135	yueF	-	-	S	-	-	-	AI-2E family transporter
ICKIEFNC_01085	3.8e-201	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
ICKIEFNC_01086	2.45e-147	tagH	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
ICKIEFNC_01087	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ICKIEFNC_01088	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
ICKIEFNC_01089	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
ICKIEFNC_01090	2.26e-139	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
ICKIEFNC_01091	4.34e-225	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ICKIEFNC_01092	1.26e-207	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
ICKIEFNC_01093	2.1e-253	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
ICKIEFNC_01094	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
ICKIEFNC_01095	3.82e-130	-	-	-	G	-	-	-	MucBP domain
ICKIEFNC_01096	3.55e-31	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
ICKIEFNC_01097	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
ICKIEFNC_01098	1.5e-22	-	-	-	-	-	-	-	-
ICKIEFNC_01099	5.69e-49	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
ICKIEFNC_01100	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ICKIEFNC_01101	1.27e-203	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
ICKIEFNC_01102	1.84e-163	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
ICKIEFNC_01103	1.02e-164	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ICKIEFNC_01104	3.45e-36	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
ICKIEFNC_01105	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
ICKIEFNC_01106	0.000189	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
ICKIEFNC_01108	4.8e-95	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
ICKIEFNC_01109	5.65e-25	-	-	-	L	ko:K07482	-	ko00000	Integrase
ICKIEFNC_01110	2.34e-47	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
ICKIEFNC_01111	7.11e-75	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
ICKIEFNC_01112	1.19e-115	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
ICKIEFNC_01113	9.87e-184	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ICKIEFNC_01114	2.26e-130	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
ICKIEFNC_01115	3.12e-214	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
ICKIEFNC_01116	2.41e-163	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
ICKIEFNC_01118	8.35e-85	-	-	-	D	-	-	-	Peptidase family M23
ICKIEFNC_01119	9.91e-47	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
ICKIEFNC_01120	4.86e-115	-	-	-	M	-	-	-	Core-2/I-Branching enzyme
ICKIEFNC_01121	1.21e-83	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
ICKIEFNC_01122	4.73e-116	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
ICKIEFNC_01123	3.45e-67	-	-	-	-	-	-	-	-
ICKIEFNC_01124	2.14e-92	licD1	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
ICKIEFNC_01125	8.17e-79	-	-	-	M	-	-	-	Glycosyltransferase like family 2
ICKIEFNC_01129	8.01e-20	-	-	-	S	-	-	-	Acyltransferase family
ICKIEFNC_01130	2.18e-29	-	-	-	S	-	-	-	Acyltransferase family
ICKIEFNC_01131	9.57e-248	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
ICKIEFNC_01132	2.97e-193	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
ICKIEFNC_01134	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
ICKIEFNC_01135	7.97e-206	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
ICKIEFNC_01136	3.27e-120	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
ICKIEFNC_01137	1.23e-85	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
ICKIEFNC_01138	8.36e-196	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
ICKIEFNC_01139	6.99e-66	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
ICKIEFNC_01140	2.13e-185	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
ICKIEFNC_01141	3.67e-43	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
ICKIEFNC_01142	5.23e-23	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
ICKIEFNC_01143	4.55e-20	-	-	-	-	-	-	-	-
ICKIEFNC_01144	1.52e-153	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
ICKIEFNC_01145	7.99e-221	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
ICKIEFNC_01146	8.54e-161	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
ICKIEFNC_01147	1.46e-213	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
ICKIEFNC_01148	4.64e-113	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
ICKIEFNC_01149	8.04e-220	-	-	-	M	-	-	-	Choline/ethanolamine kinase
ICKIEFNC_01150	8.79e-109	-	-	-	M	-	-	-	Nucleotidyl transferase
ICKIEFNC_01151	6.4e-198	-	-	-	M	-	-	-	Belongs to the BCCT transporter (TC 2.A.15) family
ICKIEFNC_01152	2.45e-66	-	-	-	S	-	-	-	peptidoglycan catabolic process
ICKIEFNC_01153	1.44e-230	XK27_08315	-	-	M	-	-	-	Sulfatase
ICKIEFNC_01155	2.77e-211	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
ICKIEFNC_01156	1.51e-316	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
ICKIEFNC_01157	3.94e-107	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
ICKIEFNC_01158	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
ICKIEFNC_01159	1.14e-81	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
ICKIEFNC_01160	3.43e-106	pncA	-	-	Q	-	-	-	isochorismatase
ICKIEFNC_01161	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
ICKIEFNC_01162	2.09e-132	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
ICKIEFNC_01163	2.72e-218	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
ICKIEFNC_01164	1.7e-55	hxlR	-	-	K	-	-	-	Transcriptional regulator, HxlR family
ICKIEFNC_01165	8.97e-208	-	-	-	C	-	-	-	Luciferase-like monooxygenase
ICKIEFNC_01166	4.46e-86	-	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
ICKIEFNC_01167	5.62e-147	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
ICKIEFNC_01168	1.06e-96	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
ICKIEFNC_01169	1.9e-74	-	-	-	EG	-	-	-	EamA-like transporter family
ICKIEFNC_01170	7.91e-149	ydbI	-	-	K	-	-	-	AI-2E family transporter
ICKIEFNC_01171	1.81e-216	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
ICKIEFNC_01172	3.53e-158	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ICKIEFNC_01173	3.27e-73	-	-	-	K	-	-	-	WYL domain
ICKIEFNC_01174	2.43e-09	-	-	-	S	-	-	-	Mor transcription activator family
ICKIEFNC_01181	1.25e-156	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
ICKIEFNC_01182	5.1e-163	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
ICKIEFNC_01183	2.11e-23	-	-	-	-	-	-	-	-
ICKIEFNC_01184	3.58e-132	-	-	-	E	-	-	-	AzlC protein
ICKIEFNC_01185	2.61e-52	-	-	-	S	-	-	-	branched-chain amino acid
ICKIEFNC_01186	3.45e-81	-	-	-	I	-	-	-	alpha/beta hydrolase fold
ICKIEFNC_01187	4.48e-24	-	-	-	-	-	-	-	-
ICKIEFNC_01188	1.3e-74	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
ICKIEFNC_01189	1.71e-27	-	-	-	-	-	-	-	-
ICKIEFNC_01190	3.07e-119	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
ICKIEFNC_01191	1.77e-115	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
ICKIEFNC_01192	1.37e-37	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
ICKIEFNC_01193	9.59e-104	-	-	-	S	-	-	-	Putative threonine/serine exporter
ICKIEFNC_01194	1.19e-65	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
ICKIEFNC_01195	1.52e-157	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
ICKIEFNC_01196	1.48e-110	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
ICKIEFNC_01197	7.86e-46	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
ICKIEFNC_01198	3.11e-28	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ICKIEFNC_01199	2.37e-28	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ICKIEFNC_01200	3.77e-83	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
ICKIEFNC_01202	1.09e-68	ccl	-	-	S	-	-	-	QueT transporter
ICKIEFNC_01203	8.54e-45	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
ICKIEFNC_01204	1.49e-129	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
ICKIEFNC_01205	1.24e-137	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
ICKIEFNC_01206	8.63e-218	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ICKIEFNC_01207	1.06e-121	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
ICKIEFNC_01208	7.83e-111	-	-	-	S	-	-	-	Alpha beta hydrolase
ICKIEFNC_01209	1.32e-57	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ICKIEFNC_01210	6.92e-175	-	-	-	V	-	-	-	MatE
ICKIEFNC_01211	6.88e-200	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
ICKIEFNC_01212	1.13e-91	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICKIEFNC_01213	2.78e-126	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
ICKIEFNC_01214	3.21e-162	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
ICKIEFNC_01215	2.76e-93	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
ICKIEFNC_01216	7.84e-33	-	-	-	-	-	-	-	-
ICKIEFNC_01217	3.39e-232	yhdP	-	-	S	-	-	-	Transporter associated domain
ICKIEFNC_01218	1.01e-100	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
ICKIEFNC_01219	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
ICKIEFNC_01220	5.89e-316	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ICKIEFNC_01221	1.24e-268	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
ICKIEFNC_01222	1e-68	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
ICKIEFNC_01223	1.03e-16	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
ICKIEFNC_01224	6.38e-123	-	-	-	-	-	-	-	-
ICKIEFNC_01225	3.89e-17	-	-	-	-	-	-	-	-
ICKIEFNC_01226	2.45e-132	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
ICKIEFNC_01227	1.03e-127	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
ICKIEFNC_01228	3.44e-111	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
ICKIEFNC_01229	1.88e-104	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
ICKIEFNC_01230	6.73e-239	steT	-	-	E	ko:K03294	-	ko00000	amino acid
ICKIEFNC_01231	1.4e-14	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
ICKIEFNC_01233	1.64e-215	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ICKIEFNC_01234	3.24e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
ICKIEFNC_01235	2.82e-140	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ICKIEFNC_01236	6.55e-130	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
ICKIEFNC_01237	1.34e-52	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
ICKIEFNC_01238	4.58e-183	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ICKIEFNC_01239	5.93e-60	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ICKIEFNC_01240	9.15e-72	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ICKIEFNC_01241	1.62e-149	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ICKIEFNC_01242	8.95e-95	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ICKIEFNC_01243	2.63e-32	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
ICKIEFNC_01244	5.05e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ICKIEFNC_01245	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ICKIEFNC_01246	3.84e-62	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ICKIEFNC_01247	1.61e-119	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ICKIEFNC_01248	4.1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ICKIEFNC_01249	5.17e-86	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ICKIEFNC_01250	4.99e-113	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ICKIEFNC_01251	2.4e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ICKIEFNC_01252	2.08e-106	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ICKIEFNC_01253	1.65e-31	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
ICKIEFNC_01254	1.13e-88	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
ICKIEFNC_01255	1.05e-266	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
ICKIEFNC_01256	8.94e-143	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
ICKIEFNC_01257	7.16e-47	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ICKIEFNC_01258	1.72e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
ICKIEFNC_01259	7.34e-74	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ICKIEFNC_01260	1.24e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ICKIEFNC_01261	1.93e-198	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICKIEFNC_01262	4.47e-71	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
ICKIEFNC_01263	1.31e-126	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICKIEFNC_01264	1.24e-139	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICKIEFNC_01265	3.1e-138	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICKIEFNC_01266	2.53e-159	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
ICKIEFNC_01267	1.04e-99	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ICKIEFNC_01268	2.29e-79	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
ICKIEFNC_01270	5.67e-307	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
ICKIEFNC_01271	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
ICKIEFNC_01272	3.3e-113	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
ICKIEFNC_01273	1.72e-142	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
ICKIEFNC_01274	5.22e-42	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
ICKIEFNC_01275	1.47e-110	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ICKIEFNC_01276	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
ICKIEFNC_01277	1.72e-60	-	-	-	M	-	-	-	LysM domain protein
ICKIEFNC_01278	2.18e-144	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
ICKIEFNC_01279	1.27e-131	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
ICKIEFNC_01280	1.16e-72	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
ICKIEFNC_01281	1.43e-68	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
ICKIEFNC_01282	3.51e-262	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ICKIEFNC_01283	6.3e-180	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ICKIEFNC_01284	2.2e-110	-	-	-	S	-	-	-	(CBS) domain
ICKIEFNC_01285	8.16e-202	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
ICKIEFNC_01286	1.68e-94	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
ICKIEFNC_01287	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ICKIEFNC_01288	4.66e-173	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
ICKIEFNC_01289	1.1e-42	yabO	-	-	J	-	-	-	S4 domain protein
ICKIEFNC_01290	1.49e-28	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
ICKIEFNC_01291	1.23e-62	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
ICKIEFNC_01292	3.67e-117	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
ICKIEFNC_01293	2.49e-100	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
ICKIEFNC_01294	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ICKIEFNC_01295	3.77e-166	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ICKIEFNC_01296	2.4e-214	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICKIEFNC_01297	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
ICKIEFNC_01301	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
ICKIEFNC_01302	9.07e-86	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
ICKIEFNC_01303	5.31e-262	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
ICKIEFNC_01304	4.86e-82	-	-	-	C	-	-	-	FMN binding
ICKIEFNC_01305	4.09e-291	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ICKIEFNC_01307	7.06e-199	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
ICKIEFNC_01308	9.91e-78	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
ICKIEFNC_01309	5.3e-12	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
ICKIEFNC_01310	3.84e-105	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
ICKIEFNC_01311	1.19e-127	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
ICKIEFNC_01312	6.41e-167	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cobalamin-independent synthase, Catalytic domain
ICKIEFNC_01313	1.14e-92	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
ICKIEFNC_01314	7.26e-250	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
ICKIEFNC_01315	1.72e-201	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
ICKIEFNC_01316	2.26e-70	oxyR5	-	-	K	-	-	-	Transcriptional regulator
ICKIEFNC_01317	1.09e-243	-	-	-	C	-	-	-	FMN_bind
ICKIEFNC_01318	8.41e-148	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
ICKIEFNC_01319	3.98e-253	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
ICKIEFNC_01320	5.9e-178	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
ICKIEFNC_01321	6.73e-102	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
ICKIEFNC_01322	1.54e-83	-	-	-	G	-	-	-	PTS system sorbose subfamily IIB component
ICKIEFNC_01323	2.83e-127	-	-	-	G	-	-	-	PTS system sorbose-specific iic component
ICKIEFNC_01324	4.8e-157	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
ICKIEFNC_01325	5.79e-51	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
ICKIEFNC_01326	2.06e-291	treC	-	-	G	-	-	-	Psort location Cytoplasmic, score
ICKIEFNC_01327	3.48e-143	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
ICKIEFNC_01328	1.7e-168	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
ICKIEFNC_01329	2.64e-98	-	-	-	S	-	-	-	intracellular protease amidase
ICKIEFNC_01330	1.12e-28	-	-	-	K	-	-	-	transcriptional regulator
ICKIEFNC_01331	2.04e-189	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
ICKIEFNC_01332	5.2e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
ICKIEFNC_01333	4.15e-26	-	-	-	S	-	-	-	Cupredoxin-like domain
ICKIEFNC_01334	2.3e-314	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
ICKIEFNC_01335	1.28e-77	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
ICKIEFNC_01336	7.69e-73	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
ICKIEFNC_01337	6.95e-112	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ICKIEFNC_01338	5.46e-276	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
ICKIEFNC_01339	2.65e-255	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
ICKIEFNC_01340	1.97e-189	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICKIEFNC_01341	7.43e-217	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICKIEFNC_01342	3.5e-229	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
ICKIEFNC_01343	9.89e-197	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
ICKIEFNC_01344	1.85e-21	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
ICKIEFNC_01345	5.54e-264	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
ICKIEFNC_01346	9.27e-145	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
ICKIEFNC_01347	2.35e-51	-	-	-	K	-	-	-	LytTr DNA-binding domain
ICKIEFNC_01349	2.6e-191	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
ICKIEFNC_01350	1.17e-30	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
ICKIEFNC_01351	1.03e-59	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
ICKIEFNC_01352	5.58e-69	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ICKIEFNC_01353	1.49e-208	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
ICKIEFNC_01354	4.78e-86	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter
ICKIEFNC_01355	2.53e-130	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
ICKIEFNC_01356	1.22e-57	ytcD	-	-	K	-	-	-	HxlR-like helix-turn-helix
ICKIEFNC_01357	9.06e-152	ytbE	-	-	S	-	-	-	reductase
ICKIEFNC_01358	1.92e-92	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ICKIEFNC_01361	4.5e-25	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ICKIEFNC_01362	2.34e-122	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
ICKIEFNC_01363	1.02e-187	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
ICKIEFNC_01364	1.74e-106	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
ICKIEFNC_01365	4.2e-45	aguA	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Porphyromonas-type peptidyl-arginine deiminase
ICKIEFNC_01367	1.3e-52	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
ICKIEFNC_01368	5.56e-61	hmpT	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
ICKIEFNC_01369	2.05e-86	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
ICKIEFNC_01371	3.19e-139	dat	2.6.1.21	-	EH	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	PFAM aminotransferase, class IV
ICKIEFNC_01372	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
ICKIEFNC_01373	8.75e-60	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
ICKIEFNC_01374	1.3e-67	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
ICKIEFNC_01378	2.33e-163	-	-	-	S	ko:K06919	-	ko00000	D5 N terminal like
ICKIEFNC_01379	1.02e-45	-	-	-	L	-	-	-	DNA replication protein
ICKIEFNC_01386	4.58e-16	xre	-	-	K	-	-	-	sequence-specific DNA binding
ICKIEFNC_01387	0.000157	-	-	-	K	-	-	-	COG NOG21982 non supervised orthologous group
ICKIEFNC_01388	4.74e-45	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
ICKIEFNC_01390	1.76e-158	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
ICKIEFNC_01391	1.8e-69	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
ICKIEFNC_01392	2.21e-73	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
ICKIEFNC_01393	1.46e-42	-	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
ICKIEFNC_01394	1.71e-97	azlC	-	-	E	-	-	-	branched-chain amino acid
ICKIEFNC_01395	1.88e-74	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
ICKIEFNC_01396	3.49e-149	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
ICKIEFNC_01397	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
ICKIEFNC_01398	2.67e-45	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
ICKIEFNC_01399	1.24e-239	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
ICKIEFNC_01400	3.94e-139	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
ICKIEFNC_01402	1.59e-261	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
ICKIEFNC_01403	2.02e-78	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ICKIEFNC_01404	8.94e-146	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
ICKIEFNC_01405	8.78e-192	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
ICKIEFNC_01406	4.9e-89	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
ICKIEFNC_01407	1.7e-66	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
ICKIEFNC_01408	3.08e-135	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
ICKIEFNC_01409	2e-220	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
ICKIEFNC_01410	2.19e-257	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
ICKIEFNC_01411	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
ICKIEFNC_01412	3.9e-134	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
ICKIEFNC_01413	1.17e-127	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
ICKIEFNC_01414	3.36e-122	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
ICKIEFNC_01415	1.86e-49	-	-	-	K	-	-	-	Transcriptional regulator
ICKIEFNC_01416	6.4e-138	-	-	-	P	-	-	-	Integral membrane protein TerC family
ICKIEFNC_01417	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
ICKIEFNC_01418	1.63e-85	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICKIEFNC_01419	2.84e-234	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
ICKIEFNC_01420	5.09e-56	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
ICKIEFNC_01421	3.12e-121	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
ICKIEFNC_01423	4.21e-53	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
ICKIEFNC_01424	1.15e-198	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
ICKIEFNC_01425	1.57e-123	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ICKIEFNC_01426	1.42e-197	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ICKIEFNC_01427	1.86e-178	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ICKIEFNC_01428	1.75e-45	-	-	-	-	-	-	-	-
ICKIEFNC_01429	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
ICKIEFNC_01430	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
ICKIEFNC_01431	2.06e-82	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
ICKIEFNC_01433	6.05e-94	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
ICKIEFNC_01434	4.95e-55	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
ICKIEFNC_01435	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
ICKIEFNC_01436	2.48e-89	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
ICKIEFNC_01437	4.74e-161	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
ICKIEFNC_01438	5.14e-130	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
ICKIEFNC_01439	6.46e-85	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
ICKIEFNC_01440	5.79e-152	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
ICKIEFNC_01441	2.39e-137	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
ICKIEFNC_01442	3.11e-33	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
ICKIEFNC_01443	2.94e-242	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
ICKIEFNC_01444	2.21e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
ICKIEFNC_01445	3.04e-20	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
ICKIEFNC_01446	2.75e-46	-	-	-	-	-	-	-	-
ICKIEFNC_01447	2.09e-131	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
ICKIEFNC_01448	1.86e-125	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
ICKIEFNC_01449	6.01e-139	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
ICKIEFNC_01450	1.98e-71	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
ICKIEFNC_01451	3.49e-130	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
ICKIEFNC_01452	7.64e-114	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
ICKIEFNC_01453	1.17e-35	adhR	-	-	K	-	-	-	transcriptional regulator
ICKIEFNC_01454	1.09e-87	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
ICKIEFNC_01456	1.11e-192	-	-	-	EGP	-	-	-	Major Facilitator
ICKIEFNC_01457	1.03e-81	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
ICKIEFNC_01458	1.3e-114	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
ICKIEFNC_01459	2.09e-46	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
ICKIEFNC_01460	2.44e-149	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
ICKIEFNC_01461	6.25e-77	-	-	-	S	-	-	-	Glycosyltransferase like family 2
ICKIEFNC_01462	1.78e-171	tetA	-	-	EGP	ko:K08151,ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko01504,ko02000	Major facilitator Superfamily
ICKIEFNC_01463	2.51e-43	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
ICKIEFNC_01464	6.18e-267	potE	-	-	E	-	-	-	Amino Acid
ICKIEFNC_01465	2e-240	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
ICKIEFNC_01466	3.91e-143	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
ICKIEFNC_01467	3.94e-56	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
ICKIEFNC_01468	9.14e-170	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
ICKIEFNC_01469	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
ICKIEFNC_01470	4.33e-61	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
ICKIEFNC_01471	5.89e-60	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
ICKIEFNC_01472	4.35e-48	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
ICKIEFNC_01474	6.37e-141	-	-	-	K	-	-	-	IrrE N-terminal-like domain
ICKIEFNC_01475	1.64e-14	-	-	-	-	-	-	-	-
ICKIEFNC_01476	4.84e-47	-	-	-	-	-	-	-	-
ICKIEFNC_01477	1.09e-58	-	-	-	-	-	-	-	-
ICKIEFNC_01478	6.3e-273	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
ICKIEFNC_01479	1.17e-07	-	-	-	-	-	-	-	-
ICKIEFNC_01481	3.21e-10	-	-	-	L	-	-	-	T/G mismatch-specific endonuclease activity
ICKIEFNC_01482	2.07e-153	-	-	-	L	-	-	-	T/G mismatch-specific endonuclease activity
ICKIEFNC_01484	8.54e-63	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
ICKIEFNC_01486	3.2e-134	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
ICKIEFNC_01488	1.66e-239	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
ICKIEFNC_01489	6.06e-77	-	-	-	S	-	-	-	COG NOG19168 non supervised orthologous group
ICKIEFNC_01491	1.4e-133	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
ICKIEFNC_01493	3.52e-287	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
ICKIEFNC_01494	1.61e-55	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
ICKIEFNC_01495	1.28e-60	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICKIEFNC_01496	8.22e-90	rdrB	-	-	K	ko:K02444,ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
ICKIEFNC_01497	3.98e-155	yvgN	-	-	C	-	-	-	Aldo keto reductase
ICKIEFNC_01498	6.9e-156	yvgN	-	-	C	-	-	-	Aldo keto reductase
ICKIEFNC_01506	2.79e-17	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
ICKIEFNC_01507	2.18e-52	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
ICKIEFNC_01508	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
ICKIEFNC_01509	2.21e-47	-	-	-	-	-	-	-	-
ICKIEFNC_01511	3.22e-161	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
ICKIEFNC_01512	6.78e-16	licT	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
ICKIEFNC_01513	1.94e-102	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
ICKIEFNC_01514	1.11e-172	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
ICKIEFNC_01515	5.2e-45	-	-	-	S	-	-	-	Replication initiator protein A (RepA) N-terminus
ICKIEFNC_01516	3.24e-142	-	-	-	L	-	-	-	Initiator Replication protein
ICKIEFNC_01520	3.84e-26	-	-	-	L	-	-	-	PLD-like domain
ICKIEFNC_01521	4.29e-91	-	-	-	L	-	-	-	HTH-like domain
ICKIEFNC_01522	8.56e-39	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
ICKIEFNC_01523	8.26e-127	-	-	-	L	-	-	-	PLD-like domain
ICKIEFNC_01525	0.000188	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
ICKIEFNC_01527	2.94e-289	fusA1	-	-	J	-	-	-	elongation factor G
ICKIEFNC_01528	5.44e-43	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ICKIEFNC_01529	1.16e-08	-	-	-	-	-	-	-	-
ICKIEFNC_01530	5.07e-270	potE	-	-	E	-	-	-	Amino Acid
ICKIEFNC_01531	1.31e-45	yphA	-	-	GM	-	-	-	NAD dependent epimerase/dehydratase family
ICKIEFNC_01532	2.33e-95	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
ICKIEFNC_01533	4.52e-118	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ICKIEFNC_01534	4.39e-162	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
ICKIEFNC_01535	2.9e-114	nanK	-	-	GK	-	-	-	ROK family
ICKIEFNC_01536	4.37e-70	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
ICKIEFNC_01537	1.74e-80	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
ICKIEFNC_01538	3.11e-191	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
ICKIEFNC_01539	1.02e-259	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ICKIEFNC_01540	4.48e-95	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
ICKIEFNC_01541	1.05e-143	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
ICKIEFNC_01542	5.79e-54	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
ICKIEFNC_01543	2.27e-86	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
ICKIEFNC_01544	2.66e-102	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
ICKIEFNC_01545	3.3e-236	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
ICKIEFNC_01547	4.81e-19	-	-	-	-	-	-	-	-
ICKIEFNC_01548	5.15e-114	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
ICKIEFNC_01551	3e-90	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
ICKIEFNC_01552	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
ICKIEFNC_01557	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
ICKIEFNC_01558	8.76e-125	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
ICKIEFNC_01559	4.78e-31	-	-	-	S	-	-	-	Phage minor capsid protein 2
ICKIEFNC_01564	8.68e-09	-	-	-	-	-	-	-	-
ICKIEFNC_01567	9.04e-61	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
ICKIEFNC_01568	1.86e-32	-	-	-	M	-	-	-	by MetaGeneAnnotator
ICKIEFNC_01569	1.37e-140	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
ICKIEFNC_01570	1.01e-93	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
ICKIEFNC_01571	7.01e-57	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
ICKIEFNC_01572	1.93e-106	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
ICKIEFNC_01573	1.09e-172	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
ICKIEFNC_01574	2.21e-47	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
ICKIEFNC_01575	1.34e-81	mipB	2.2.1.2	-	H	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
ICKIEFNC_01576	2.37e-147	ddh	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
ICKIEFNC_01577	1.1e-172	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
ICKIEFNC_01578	5.02e-35	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
ICKIEFNC_01579	1.73e-31	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
ICKIEFNC_01580	6.35e-281	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
ICKIEFNC_01581	6.09e-147	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
ICKIEFNC_01582	8.63e-179	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
ICKIEFNC_01583	1.61e-181	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ICKIEFNC_01584	1.15e-53	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
ICKIEFNC_01585	2.63e-303	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
ICKIEFNC_01586	8.8e-64	-	-	-	S	-	-	-	VIT family
ICKIEFNC_01587	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
ICKIEFNC_01588	5.49e-175	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ICKIEFNC_01589	2.15e-141	rssA	-	-	S	-	-	-	Phospholipase, patatin family
ICKIEFNC_01590	3.76e-18	-	-	-	-	-	-	-	-
ICKIEFNC_01591	1.42e-34	-	-	-	-	-	-	-	-
ICKIEFNC_01592	5e-100	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
ICKIEFNC_01593	1.15e-126	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ICKIEFNC_01594	8.46e-101	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
ICKIEFNC_01595	3.14e-66	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
ICKIEFNC_01596	4.82e-72	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
ICKIEFNC_01597	1.67e-97	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
ICKIEFNC_01598	3.82e-32	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
ICKIEFNC_01599	1.06e-13	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
ICKIEFNC_01600	8.01e-128	bsh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
ICKIEFNC_01605	2.19e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF4417)
ICKIEFNC_01606	4.43e-181	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase family
ICKIEFNC_01607	1.03e-90	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
ICKIEFNC_01608	2.97e-175	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ICKIEFNC_01609	2.95e-271	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	FAD binding domain
ICKIEFNC_01610	1.16e-146	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
ICKIEFNC_01611	6.08e-176	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
ICKIEFNC_01612	3.72e-89	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
ICKIEFNC_01613	7.05e-123	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
ICKIEFNC_01614	7.6e-168	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
ICKIEFNC_01615	3.04e-44	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
ICKIEFNC_01616	6.56e-52	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
ICKIEFNC_01617	1.2e-28	-	-	-	L	ko:K07483	-	ko00000	PFAM transposase IS3 IS911 family protein
ICKIEFNC_01618	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
ICKIEFNC_01619	3.43e-45	-	-	-	P	-	-	-	Heavy-metal-associated domain
ICKIEFNC_01620	1.32e-33	-	-	-	L	ko:K07498	-	ko00000	Transposase
ICKIEFNC_01621	2.64e-26	tnp	-	-	-	ko:K07498	-	ko00000	-
ICKIEFNC_01622	1.54e-55	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
ICKIEFNC_01623	1.43e-160	-	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
ICKIEFNC_01624	8.45e-120	-	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
ICKIEFNC_01625	2.85e-197	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
ICKIEFNC_01626	2.01e-76	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
ICKIEFNC_01627	1.22e-66	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
ICKIEFNC_01628	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
ICKIEFNC_01629	1.73e-49	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
ICKIEFNC_01630	8.45e-147	-	-	-	O	-	-	-	AAA domain (Cdc48 subfamily)
ICKIEFNC_01631	9.08e-86	-	-	-	-	-	-	-	-
ICKIEFNC_01632	6.91e-105	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
ICKIEFNC_01633	5.85e-290	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
ICKIEFNC_01634	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	DEAD/DEAH box helicase
ICKIEFNC_01636	1.96e-59	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
ICKIEFNC_01637	3.26e-102	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
ICKIEFNC_01638	2.29e-75	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
ICKIEFNC_01639	1.11e-147	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ICKIEFNC_01640	6.4e-183	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
ICKIEFNC_01641	1.43e-206	potE2	-	-	E	ko:K03294	-	ko00000	amino acid
ICKIEFNC_01644	1.67e-15	-	-	-	-	-	-	-	-
ICKIEFNC_01647	1.47e-113	yeeC	-	-	P	-	-	-	T5orf172
ICKIEFNC_01648	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
ICKIEFNC_01649	7.66e-252	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
ICKIEFNC_01650	3.12e-105	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
ICKIEFNC_01652	3.97e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF4256)
ICKIEFNC_01653	7e-161	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
ICKIEFNC_01654	1.02e-73	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
ICKIEFNC_01655	1.26e-191	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ICKIEFNC_01657	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
ICKIEFNC_01658	4.28e-214	npr	1.11.1.1	-	S	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
ICKIEFNC_01659	1.16e-136	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
ICKIEFNC_01660	1.44e-104	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
ICKIEFNC_01661	2.84e-107	-	-	-	C	-	-	-	nitroreductase
ICKIEFNC_01662	8.69e-166	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
ICKIEFNC_01663	5.23e-119	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
ICKIEFNC_01664	2.65e-188	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ICKIEFNC_01665	6.31e-137	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
ICKIEFNC_01666	1.04e-178	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
ICKIEFNC_01667	1.03e-59	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
ICKIEFNC_01668	1.23e-77	yphH	-	-	S	-	-	-	Cupin domain
ICKIEFNC_01669	1.56e-62	-	-	-	C	-	-	-	Flavodoxin
ICKIEFNC_01670	1.99e-70	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
ICKIEFNC_01671	1.56e-131	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
ICKIEFNC_01672	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
ICKIEFNC_01673	1.76e-285	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ICKIEFNC_01674	5.47e-64	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ICKIEFNC_01675	2.89e-86	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
ICKIEFNC_01676	8.15e-138	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
ICKIEFNC_01677	9.74e-147	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
ICKIEFNC_01678	2.63e-167	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
ICKIEFNC_01679	5.67e-202	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
ICKIEFNC_01680	6.28e-133	potC	-	-	U	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
ICKIEFNC_01681	3.85e-153	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
ICKIEFNC_01682	8.99e-212	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
ICKIEFNC_01683	8.95e-128	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
ICKIEFNC_01684	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
ICKIEFNC_01685	4.13e-296	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ICKIEFNC_01688	8.46e-23	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
ICKIEFNC_01689	1.23e-08	-	-	-	S	-	-	-	Putative adhesin
ICKIEFNC_01690	1.69e-29	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
ICKIEFNC_01691	3.6e-51	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
ICKIEFNC_01692	7.54e-39	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
ICKIEFNC_01693	7.44e-51	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ICKIEFNC_01694	4.01e-138	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ICKIEFNC_01695	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
ICKIEFNC_01696	7.26e-43	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
ICKIEFNC_01697	4.73e-97	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
ICKIEFNC_01698	4.49e-209	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICKIEFNC_01699	1.66e-163	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ICKIEFNC_01700	1.58e-90	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
ICKIEFNC_01701	1.61e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
ICKIEFNC_01702	6.92e-189	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
ICKIEFNC_01703	1.69e-153	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
ICKIEFNC_01704	1.11e-192	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
ICKIEFNC_01705	4.36e-101	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	sugar-binding domain protein
ICKIEFNC_01706	2.8e-126	baeS	-	-	T	-	-	-	Histidine kinase
ICKIEFNC_01707	1.07e-101	yfiK	-	-	K	ko:K02479	-	ko00000,ko02022	Bacterial regulatory proteins, luxR family
ICKIEFNC_01708	4.81e-147	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
ICKIEFNC_01709	1.29e-51	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ICKIEFNC_01710	2.49e-43	-	-	-	K	-	-	-	MerR HTH family regulatory protein
ICKIEFNC_01711	1.15e-245	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
ICKIEFNC_01712	5.57e-48	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
ICKIEFNC_01713	5.68e-108	-	-	-	G	-	-	-	Phosphoglycerate mutase family
ICKIEFNC_01714	1.34e-75	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
ICKIEFNC_01715	1.31e-90	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
ICKIEFNC_01716	6.94e-114	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
ICKIEFNC_01717	7.03e-228	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
ICKIEFNC_01718	0.0	-	3.2.1.80	-	GN	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Fructan beta-fructosidase
ICKIEFNC_01719	1.27e-69	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
ICKIEFNC_01720	4.52e-109	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
ICKIEFNC_01721	5.71e-28	-	-	-	-	-	-	-	-
ICKIEFNC_01722	2.69e-18	-	-	-	M	-	-	-	Glycosyl transferase family 2
ICKIEFNC_01723	2.27e-67	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
ICKIEFNC_01724	2.66e-75	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
ICKIEFNC_01725	8.44e-145	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
ICKIEFNC_01726	9.07e-228	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
ICKIEFNC_01727	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
ICKIEFNC_01728	1.28e-269	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
ICKIEFNC_01729	1.32e-185	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
ICKIEFNC_01730	3.5e-214	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
ICKIEFNC_01731	5.42e-272	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
ICKIEFNC_01733	2.88e-77	-	-	-	T	-	-	-	Universal stress protein family
ICKIEFNC_01734	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
ICKIEFNC_01735	2.65e-35	-	-	-	-	-	-	-	-
ICKIEFNC_01736	1.25e-250	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
ICKIEFNC_01737	2.14e-141	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
ICKIEFNC_01738	7.22e-107	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ICKIEFNC_01739	6.23e-187	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
ICKIEFNC_01740	1.28e-184	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
ICKIEFNC_01741	2.78e-109	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
ICKIEFNC_01743	1.77e-170	-	-	-	S	-	-	-	interspecies interaction between organisms
ICKIEFNC_01744	4.76e-261	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	glycerol-3-phosphate transporter
ICKIEFNC_01745	4.56e-93	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ICKIEFNC_01746	2.69e-186	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
ICKIEFNC_01747	1.46e-147	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
ICKIEFNC_01748	1.37e-40	-	-	-	S	-	-	-	YjbR
ICKIEFNC_01749	3.35e-100	yycI	-	-	S	-	-	-	YycH protein
ICKIEFNC_01750	2.49e-126	yycH	-	-	S	-	-	-	YycH protein
ICKIEFNC_01751	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
ICKIEFNC_01752	2.43e-151	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
ICKIEFNC_01753	5.78e-135	yxeH	-	-	S	-	-	-	hydrolase
ICKIEFNC_01754	6.08e-284	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
ICKIEFNC_01755	2.65e-270	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
ICKIEFNC_01756	2.33e-41	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
ICKIEFNC_01757	1.12e-218	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
ICKIEFNC_01758	1.02e-80	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
ICKIEFNC_01759	3.59e-172	-	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
ICKIEFNC_01760	4.93e-225	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
ICKIEFNC_01761	1.11e-134	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
ICKIEFNC_01762	2.91e-253	pepF	-	-	E	-	-	-	Oligopeptidase F
ICKIEFNC_01763	3.82e-120	yicL	-	-	EG	-	-	-	EamA-like transporter family
ICKIEFNC_01764	2.55e-89	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
ICKIEFNC_01765	1.86e-212	-	-	-	S	-	-	-	Putative threonine/serine exporter
ICKIEFNC_01766	8.05e-31	-	-	-	S	-	-	-	PFAM Archaeal ATPase
ICKIEFNC_01767	1.13e-75	-	-	-	S	-	-	-	PFAM Archaeal ATPase
ICKIEFNC_01768	1.42e-217	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
ICKIEFNC_01769	2.12e-175	tdh	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
ICKIEFNC_01770	3e-219	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
ICKIEFNC_01771	5.81e-258	uxuB	1.1.1.57	-	G	ko:K00040	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase C-terminal domain
ICKIEFNC_01772	1.89e-63	-	-	-	K	-	-	-	FCD domain
ICKIEFNC_01773	3.34e-142	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
ICKIEFNC_01774	3.67e-78	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
ICKIEFNC_01775	2.56e-140	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
ICKIEFNC_01776	4.15e-12	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ICKIEFNC_01777	1.11e-193	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
ICKIEFNC_01778	1.35e-135	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
ICKIEFNC_01779	5.08e-282	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
ICKIEFNC_01780	5.89e-289	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ICKIEFNC_01781	3.53e-22	yneR	-	-	-	-	-	-	-
ICKIEFNC_01782	2.65e-306	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
ICKIEFNC_01783	5.27e-53	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
ICKIEFNC_01784	6.11e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
ICKIEFNC_01785	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
ICKIEFNC_01786	3.2e-81	-	-	-	D	-	-	-	peptidase
ICKIEFNC_01787	6.63e-148	-	-	-	S	-	-	-	Glycosyl transferase family 2
ICKIEFNC_01788	5.79e-138	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
ICKIEFNC_01789	3.82e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ICKIEFNC_01790	6.48e-89	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
ICKIEFNC_01791	7.37e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
ICKIEFNC_01792	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ICKIEFNC_01793	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ICKIEFNC_01794	2.79e-192	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ICKIEFNC_01795	4.51e-27	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
ICKIEFNC_01796	1.81e-201	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
ICKIEFNC_01797	1.1e-257	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ICKIEFNC_01798	2.29e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
ICKIEFNC_01799	8.2e-65	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
ICKIEFNC_01800	1.54e-137	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ICKIEFNC_01801	2.06e-253	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
ICKIEFNC_01802	1.36e-151	-	-	-	S	-	-	-	Conserved hypothetical protein 698
ICKIEFNC_01803	1.77e-67	-	-	-	K	-	-	-	LysR substrate binding domain
ICKIEFNC_01805	3.65e-86	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
ICKIEFNC_01806	3.46e-39	-	-	-	S	-	-	-	Belongs to the HesB IscA family
ICKIEFNC_01808	3.49e-184	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ICKIEFNC_01809	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
ICKIEFNC_01810	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ICKIEFNC_01811	1.97e-204	camS	-	-	S	-	-	-	sex pheromone
ICKIEFNC_01812	1.34e-50	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ICKIEFNC_01813	1.03e-294	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
ICKIEFNC_01814	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ICKIEFNC_01815	8.82e-184	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
ICKIEFNC_01816	1.71e-269	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICKIEFNC_01817	7.44e-105	-	-	-	-	-	-	-	-
ICKIEFNC_01818	1.42e-59	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
ICKIEFNC_01820	2.29e-247	-	-	-	L	ko:K06400	-	ko00000	Recombinase
ICKIEFNC_01821	4.3e-09	-	-	-	L	ko:K06400	-	ko00000	Psort location Cytoplasmic, score
ICKIEFNC_01822	1.36e-140	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
ICKIEFNC_01823	1.12e-10	-	-	-	-	-	-	-	-
ICKIEFNC_01824	1.87e-66	-	-	-	S	-	-	-	Bacteriophage holin family
ICKIEFNC_01825	7e-61	-	-	-	S	-	-	-	Phage head-tail joining protein
ICKIEFNC_01826	1.85e-40	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
ICKIEFNC_01827	1.38e-214	-	-	-	S	-	-	-	Phage capsid family
ICKIEFNC_01828	7.45e-104	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
ICKIEFNC_01829	3.52e-277	-	-	-	S	-	-	-	Phage portal protein
ICKIEFNC_01830	1.33e-15	-	-	-	K	-	-	-	Antidote-toxin recognition MazE, bacterial antitoxin
ICKIEFNC_01832	0.0	-	-	-	S	-	-	-	overlaps another CDS with the same product name
ICKIEFNC_01833	3.59e-34	-	-	-	S	-	-	-	Domain of unknown function (DUF5049)
ICKIEFNC_01834	4.28e-68	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
ICKIEFNC_01835	8.8e-254	-	-	-	KL	-	-	-	DNA methylase
ICKIEFNC_01836	2.29e-119	-	-	-	-	-	-	-	-
ICKIEFNC_01837	1.4e-73	-	-	-	V	ko:K07451	-	ko00000,ko01000,ko02048	HNH nucleases
ICKIEFNC_01838	3.78e-65	-	-	-	-	-	-	-	-
ICKIEFNC_01839	1.46e-248	-	-	-	L	-	-	-	SNF2 family N-terminal domain
ICKIEFNC_01840	4.75e-43	-	-	-	S	-	-	-	VRR_NUC
ICKIEFNC_01841	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
ICKIEFNC_01842	3.1e-52	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
ICKIEFNC_01843	0.0	-	2.7.7.7	-	L	ko:K02334	-	ko00000,ko01000	DNA polymerase
ICKIEFNC_01844	1.53e-114	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
ICKIEFNC_01845	1.15e-181	-	-	-	L	-	-	-	Protein of unknown function (DUF2800)
ICKIEFNC_01846	3.57e-14	-	-	-	-	-	-	-	-
ICKIEFNC_01847	2.75e-13	-	-	-	-	-	-	-	-
ICKIEFNC_01849	3.21e-28	-	-	-	-	-	-	-	-
ICKIEFNC_01850	4.43e-09	-	-	-	-	-	-	-	-
ICKIEFNC_01851	1.71e-85	-	-	-	L	-	-	-	AAA domain
ICKIEFNC_01852	6.22e-28	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
ICKIEFNC_01853	3.33e-109	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
ICKIEFNC_01854	1.78e-143	-	-	-	L	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
ICKIEFNC_01855	0.0	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
ICKIEFNC_01856	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
ICKIEFNC_01859	2.31e-68	-	-	-	L	-	-	-	Resolvase, N terminal domain
ICKIEFNC_01860	5.64e-60	-	-	-	L	-	-	-	COG COG1961 Site-specific recombinases, DNA invertase Pin homologs
ICKIEFNC_01861	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
ICKIEFNC_01862	3.12e-32	-	-	-	-	-	-	-	-
ICKIEFNC_01863	1.36e-42	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
ICKIEFNC_01865	7.64e-70	-	-	-	S	-	-	-	UPF0489 domain
ICKIEFNC_01866	3.67e-154	-	-	-	L	ko:K07448	-	ko00000,ko02048	Mrr N-terminal domain
ICKIEFNC_01869	4.46e-94	-	-	-	S	-	-	-	Domain of unknown function (DUF4343)
ICKIEFNC_01870	5.18e-76	-	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
ICKIEFNC_01871	9.8e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF3841)
ICKIEFNC_01872	7.63e-285	-	-	-	S	-	-	-	Protein of unknown function DUF262
ICKIEFNC_01873	1.11e-206	spoVK	-	-	O	ko:K06413	-	ko00000	PFAM ATPase family associated with various cellular activities (AAA)
ICKIEFNC_01874	6.92e-198	-	-	-	C	-	-	-	Oxidoreductase
ICKIEFNC_01875	3.59e-92	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
ICKIEFNC_01876	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
ICKIEFNC_01877	7.38e-123	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ICKIEFNC_01878	3.47e-75	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
ICKIEFNC_01879	2.02e-221	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
ICKIEFNC_01880	4.82e-20	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
ICKIEFNC_01881	1.02e-299	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
ICKIEFNC_01882	4.58e-248	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
ICKIEFNC_01883	7.68e-269	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
ICKIEFNC_01884	7.64e-51	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
ICKIEFNC_01885	2.44e-202	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ICKIEFNC_01886	4.73e-79	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
ICKIEFNC_01887	3.93e-128	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
ICKIEFNC_01888	5.57e-118	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
ICKIEFNC_01889	2.24e-16	-	3.5.1.28	CBM50	M	ko:K22409	-	ko00000,ko01000	Lysin motif
ICKIEFNC_01890	5.63e-195	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
ICKIEFNC_01891	3.03e-183	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
ICKIEFNC_01892	5.84e-68	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
ICKIEFNC_01893	5.64e-69	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
ICKIEFNC_01894	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
ICKIEFNC_01895	1.39e-151	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
ICKIEFNC_01896	1.52e-153	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
ICKIEFNC_01897	4.88e-90	-	-	-	K	-	-	-	Sugar-specific transcriptional regulator TrmB
ICKIEFNC_01898	1.92e-213	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
ICKIEFNC_01899	7.04e-229	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
ICKIEFNC_01900	0.0	-	-	-	E	-	-	-	Amino acid permease
ICKIEFNC_01901	7.42e-109	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
ICKIEFNC_01902	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
ICKIEFNC_01903	3.84e-95	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
ICKIEFNC_01904	1.05e-271	-	-	-	G	ko:K16211	-	ko00000,ko02000	Transporter, major facilitator family protein
ICKIEFNC_01905	4.67e-126	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
ICKIEFNC_01906	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
ICKIEFNC_01909	2.81e-201	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
ICKIEFNC_01910	7.62e-161	mocA	-	-	S	-	-	-	Oxidoreductase
ICKIEFNC_01911	1.13e-32	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
ICKIEFNC_01912	3.47e-215	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
ICKIEFNC_01913	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
ICKIEFNC_01914	1.82e-243	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
ICKIEFNC_01915	5.53e-157	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
ICKIEFNC_01916	1.95e-208	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ICKIEFNC_01917	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ICKIEFNC_01918	3.1e-274	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
ICKIEFNC_01919	2.04e-45	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
ICKIEFNC_01920	2.41e-276	gdhA	1.4.1.3, 1.4.1.4	-	E	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	ko00000,ko00001,ko00002,ko01000,ko04147	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
ICKIEFNC_01921	3.23e-262	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
ICKIEFNC_01922	3.18e-07	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
ICKIEFNC_01923	1.96e-54	-	-	-	-	-	-	-	-
ICKIEFNC_01925	3.51e-228	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
ICKIEFNC_01926	6.89e-118	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
ICKIEFNC_01927	1.79e-148	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ICKIEFNC_01928	5.56e-124	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
ICKIEFNC_01929	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
ICKIEFNC_01930	4.89e-50	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
ICKIEFNC_01931	3.15e-254	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
ICKIEFNC_01932	3.92e-96	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
ICKIEFNC_01933	3.17e-78	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
ICKIEFNC_01934	3.28e-81	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
ICKIEFNC_01935	5.35e-18	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
ICKIEFNC_01936	1.23e-315	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
ICKIEFNC_01937	3.21e-89	mleR	-	-	K	-	-	-	LysR family
ICKIEFNC_01938	1.27e-74	napB	-	-	K	-	-	-	transcriptional
ICKIEFNC_01939	1.04e-51	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ICKIEFNC_01940	3.27e-78	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
ICKIEFNC_01941	1.49e-56	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
ICKIEFNC_01942	2.39e-11	fhaB	-	-	M	ko:K15125,ko:K18491	ko04550,ko05133,map04550,map05133	ko00000,ko00001,ko00536,ko03000	translation initiation factor activity