ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HIKJKDOL_00002 3.96e-163 ymaC - - S - - - Replication protein
HIKJKDOL_00003 5.98e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
HIKJKDOL_00004 3.04e-71 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
HIKJKDOL_00005 2.02e-66 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HIKJKDOL_00007 5.41e-76 ymaF - - S - - - YmaF family
HIKJKDOL_00008 1.96e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HIKJKDOL_00009 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HIKJKDOL_00010 1.63e-31 - - - - - - - -
HIKJKDOL_00011 1.2e-30 ymzA - - - - - - -
HIKJKDOL_00012 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
HIKJKDOL_00013 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIKJKDOL_00014 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIKJKDOL_00015 2.24e-141 - - - - - - - -
HIKJKDOL_00016 2.34e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HIKJKDOL_00017 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
HIKJKDOL_00018 1.82e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HIKJKDOL_00019 1.95e-309 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HIKJKDOL_00020 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
HIKJKDOL_00021 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HIKJKDOL_00022 3.07e-171 - - - L - - - Belongs to the 'phage' integrase family
HIKJKDOL_00023 5.75e-22 - - - E - - - IrrE N-terminal-like domain
HIKJKDOL_00024 5.18e-15 - - - K - - - Cro/C1-type HTH DNA-binding domain
HIKJKDOL_00026 2.88e-67 - - - S - - - Phage regulatory protein Rha (Phage_pRha)
HIKJKDOL_00027 1.36e-27 - - - - - - - -
HIKJKDOL_00029 2.94e-27 - - - S - - - Uncharacterized protein YqaH
HIKJKDOL_00031 1.26e-118 - - - S - - - DNA protection
HIKJKDOL_00032 1.84e-211 - - - D - - - AAA domain
HIKJKDOL_00034 3.37e-93 - - - S - - - Protein of unknown function (DUF669)
HIKJKDOL_00035 0.0 - - - S - - - hydrolase activity
HIKJKDOL_00036 4.78e-95 - - - - - - - -
HIKJKDOL_00037 5.22e-120 - - - S - - - nuclease activity
HIKJKDOL_00038 2.05e-104 - - - - - - - -
HIKJKDOL_00041 4.53e-79 - - - - - - - -
HIKJKDOL_00045 2.75e-52 - - - T - - - Histidine kinase
HIKJKDOL_00046 2.4e-66 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
HIKJKDOL_00047 2.11e-101 - - - L - - - phage terminase small subunit
HIKJKDOL_00048 0.0 - - - S - - - Terminase
HIKJKDOL_00049 2.24e-219 - - - S - - - Phage portal protein
HIKJKDOL_00050 6.5e-103 - - - S - - - peptidase activity
HIKJKDOL_00051 3.19e-203 - - - S - - - capsid protein
HIKJKDOL_00052 3.69e-35 - - - - - - - -
HIKJKDOL_00053 3.43e-51 - - - S - - - Phage gp6-like head-tail connector protein
HIKJKDOL_00054 1.5e-51 - - - S - - - Phage head-tail joining protein
HIKJKDOL_00055 1.19e-66 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HIKJKDOL_00057 9.71e-103 - - - N - - - Phage major tail protein phi13
HIKJKDOL_00058 1.77e-05 - - - - - - - -
HIKJKDOL_00060 0.0 - - - D - - - phage tail tape measure protein
HIKJKDOL_00061 8.38e-143 - - - S - - - Phage tail protein
HIKJKDOL_00062 3.34e-276 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
HIKJKDOL_00063 0.0 - - - S - - - Peptidase_G2, IMC autoproteolytic cleavage domain
HIKJKDOL_00064 3.69e-107 - - - - - - - -
HIKJKDOL_00067 1.17e-121 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
HIKJKDOL_00068 1.77e-73 - - - S - - - Pfam:Phage_holin_4_1
HIKJKDOL_00069 2.16e-161 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HIKJKDOL_00070 9.45e-104 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
HIKJKDOL_00071 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HIKJKDOL_00072 1.38e-132 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HIKJKDOL_00076 8.68e-14 - - - - - - - -
HIKJKDOL_00077 2.03e-39 - - - - - - - -
HIKJKDOL_00078 2.22e-23 - - - - - - - -
HIKJKDOL_00079 2.05e-116 - - - G - - - SMI1-KNR4 cell-wall
HIKJKDOL_00080 6.64e-145 ynaC - - - - - - -
HIKJKDOL_00081 2.61e-15 - - - S - - - Protein of unknown function (DUF1433)
HIKJKDOL_00082 8.3e-126 ynaD - - J - - - Acetyltransferase (GNAT) domain
HIKJKDOL_00083 1.14e-90 - - - S - - - CAAX protease self-immunity
HIKJKDOL_00084 8.48e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HIKJKDOL_00085 8.64e-34 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HIKJKDOL_00086 5.71e-152 - - - S - - - Domain of unknown function (DUF3885)
HIKJKDOL_00087 7.31e-21 ynaF - - - - - - -
HIKJKDOL_00089 2.81e-106 - - - E - - - phosphoribosylanthranilate isomerase activity
HIKJKDOL_00090 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
HIKJKDOL_00091 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HIKJKDOL_00092 6.82e-273 xylR - - GK - - - ROK family
HIKJKDOL_00093 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
HIKJKDOL_00094 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
HIKJKDOL_00095 7.18e-145 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
HIKJKDOL_00096 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HIKJKDOL_00097 4.34e-281 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HIKJKDOL_00099 1.22e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
HIKJKDOL_00100 7.54e-22 - - - - - - - -
HIKJKDOL_00103 7.89e-210 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HIKJKDOL_00105 2.43e-162 - - - S - - - Domain of unknown function, YrpD
HIKJKDOL_00108 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
HIKJKDOL_00109 8.92e-96 - - - - - - - -
HIKJKDOL_00110 3.12e-104 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
HIKJKDOL_00113 9.36e-65 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HIKJKDOL_00114 1.82e-181 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HIKJKDOL_00115 5.45e-112 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
HIKJKDOL_00116 9.15e-199 yndG - - S - - - DoxX-like family
HIKJKDOL_00117 1.26e-151 - - - S - - - Domain of unknown function (DUF4166)
HIKJKDOL_00118 0.0 yndJ - - S - - - YndJ-like protein
HIKJKDOL_00120 1.68e-177 yndL - - S - - - Replication protein
HIKJKDOL_00121 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
HIKJKDOL_00122 7.89e-99 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HIKJKDOL_00123 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HIKJKDOL_00124 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HIKJKDOL_00125 5.4e-143 yneB - - L - - - resolvase
HIKJKDOL_00126 1.15e-43 ynzC - - S - - - UPF0291 protein
HIKJKDOL_00127 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HIKJKDOL_00128 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
HIKJKDOL_00129 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
HIKJKDOL_00130 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
HIKJKDOL_00131 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
HIKJKDOL_00132 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
HIKJKDOL_00133 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
HIKJKDOL_00134 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
HIKJKDOL_00135 7.02e-86 cotM - - O ko:K06335 - ko00000 Spore coat protein
HIKJKDOL_00136 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
HIKJKDOL_00137 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
HIKJKDOL_00138 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HIKJKDOL_00139 8.82e-119 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HIKJKDOL_00140 9.26e-10 - - - S - - - Fur-regulated basic protein B
HIKJKDOL_00142 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
HIKJKDOL_00143 1.15e-94 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
HIKJKDOL_00144 3.3e-71 yneQ - - - - - - -
HIKJKDOL_00145 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
HIKJKDOL_00146 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HIKJKDOL_00147 1.72e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
HIKJKDOL_00148 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HIKJKDOL_00149 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HIKJKDOL_00150 1.82e-18 - - - - - - - -
HIKJKDOL_00151 1.06e-75 ynfC - - - - - - -
HIKJKDOL_00152 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
HIKJKDOL_00153 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
HIKJKDOL_00155 9.85e-317 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
HIKJKDOL_00156 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HIKJKDOL_00157 2.45e-103 yngA - - S - - - membrane
HIKJKDOL_00158 4.54e-209 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HIKJKDOL_00159 2.01e-134 yngC - - S - - - membrane-associated protein
HIKJKDOL_00160 5.83e-293 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
HIKJKDOL_00161 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HIKJKDOL_00162 4.25e-175 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
HIKJKDOL_00163 4.54e-210 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
HIKJKDOL_00164 2.4e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
HIKJKDOL_00165 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
HIKJKDOL_00166 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HIKJKDOL_00167 1.47e-265 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
HIKJKDOL_00168 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
HIKJKDOL_00169 1.01e-82 yngL - - S - - - Protein of unknown function (DUF1360)
HIKJKDOL_00170 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
HIKJKDOL_00171 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIKJKDOL_00172 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIKJKDOL_00173 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIKJKDOL_00174 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIKJKDOL_00175 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HIKJKDOL_00176 4.92e-243 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HIKJKDOL_00177 9.8e-313 yoeA - - V - - - MATE efflux family protein
HIKJKDOL_00178 6.86e-126 yoeB - - S - - - IseA DL-endopeptidase inhibitor
HIKJKDOL_00180 1.14e-124 - - - L - - - Integrase
HIKJKDOL_00181 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
HIKJKDOL_00182 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
HIKJKDOL_00183 3.57e-200 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
HIKJKDOL_00184 1.15e-234 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HIKJKDOL_00185 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HIKJKDOL_00186 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
HIKJKDOL_00187 2.14e-204 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
HIKJKDOL_00188 2.33e-262 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HIKJKDOL_00189 2.72e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIKJKDOL_00190 5.59e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HIKJKDOL_00191 1.47e-155 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HIKJKDOL_00192 9.05e-52 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
HIKJKDOL_00193 1.58e-167 yoxB - - - - - - -
HIKJKDOL_00194 5.23e-119 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HIKJKDOL_00195 4.18e-166 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HIKJKDOL_00196 1.77e-121 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HIKJKDOL_00197 7.07e-177 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HIKJKDOL_00198 4.72e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HIKJKDOL_00199 7.48e-299 yoaB - - EGP - - - the major facilitator superfamily
HIKJKDOL_00200 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
HIKJKDOL_00201 3.57e-89 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIKJKDOL_00202 1.51e-126 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIKJKDOL_00203 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HIKJKDOL_00204 3.48e-43 yoaF - - - - - - -
HIKJKDOL_00205 5.83e-216 - - - EGP ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HIKJKDOL_00206 3.41e-259 - - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HIKJKDOL_00207 3.73e-193 - 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
HIKJKDOL_00208 1.99e-114 degA - - K - - - Transcriptional regulator
HIKJKDOL_00209 1.17e-12 - - - - - - - -
HIKJKDOL_00210 1.25e-20 - - - - - - - -
HIKJKDOL_00211 8.23e-62 - - - S - - - Protein of unknown function (DUF4025)
HIKJKDOL_00212 0.0 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
HIKJKDOL_00213 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
HIKJKDOL_00214 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
HIKJKDOL_00215 1.79e-145 yoaK - - S - - - Membrane
HIKJKDOL_00216 5e-253 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
HIKJKDOL_00217 5.08e-171 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
HIKJKDOL_00219 3.1e-293 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
HIKJKDOL_00222 1.08e-112 - - - - - - - -
HIKJKDOL_00223 1.48e-217 yoaR - - V - - - vancomycin resistance protein
HIKJKDOL_00224 2.65e-97 yoaS - - S - - - Protein of unknown function (DUF2975)
HIKJKDOL_00225 7.19e-41 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HIKJKDOL_00226 1.57e-188 yoaT - - S - - - Protein of unknown function (DUF817)
HIKJKDOL_00227 6.67e-203 yoaU - - K - - - LysR substrate binding domain
HIKJKDOL_00228 1.83e-201 yoaV - - EG - - - EamA-like transporter family
HIKJKDOL_00229 5.63e-102 yoaW - - - - - - -
HIKJKDOL_00230 2.07e-148 lin0465 - - S - - - DJ-1/PfpI family
HIKJKDOL_00231 1.65e-211 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
HIKJKDOL_00234 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
HIKJKDOL_00235 7.53e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
HIKJKDOL_00237 7.64e-60 - - - - - - - -
HIKJKDOL_00239 1.31e-226 kdpD 2.7.13.3 - T ko:K07646 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HIKJKDOL_00240 3.12e-82 kdpC 3.6.3.12 - P ko:K01548 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HIKJKDOL_00241 0.0 kdpB 3.6.3.12 - P ko:K01547 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HIKJKDOL_00242 0.0 kdpA 3.6.3.12 - P ko:K01546 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HIKJKDOL_00244 9.14e-110 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
HIKJKDOL_00245 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HIKJKDOL_00246 1.33e-130 yokH - - G - - - SMI1 / KNR4 family
HIKJKDOL_00247 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
HIKJKDOL_00248 0.0 yobO - - M - - - Pectate lyase superfamily protein
HIKJKDOL_00249 5.21e-71 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
HIKJKDOL_00250 2.13e-174 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
HIKJKDOL_00251 1.45e-180 - - - J - - - FR47-like protein
HIKJKDOL_00252 3.09e-127 yobS - - K - - - Transcriptional regulator
HIKJKDOL_00253 2.22e-168 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HIKJKDOL_00254 8.64e-112 - - - K - - - Bacterial transcription activator, effector binding domain
HIKJKDOL_00255 1.12e-219 yobV - - K - - - WYL domain
HIKJKDOL_00256 1.37e-116 yobW - - - - - - -
HIKJKDOL_00257 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
HIKJKDOL_00258 3.28e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HIKJKDOL_00259 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
HIKJKDOL_00260 2.91e-182 - - - - - - - -
HIKJKDOL_00261 1.08e-121 yocC - - - - - - -
HIKJKDOL_00262 1.21e-243 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
HIKJKDOL_00263 3.99e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
HIKJKDOL_00264 2.37e-250 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HIKJKDOL_00265 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIKJKDOL_00266 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
HIKJKDOL_00267 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
HIKJKDOL_00268 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HIKJKDOL_00269 1.42e-107 yocK - - T - - - general stress protein
HIKJKDOL_00270 3.02e-70 yocL - - - - - - -
HIKJKDOL_00271 7.29e-46 - - - - - - - -
HIKJKDOL_00272 6.6e-115 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HIKJKDOL_00273 2.94e-55 yozN - - - - - - -
HIKJKDOL_00274 1.83e-49 yocN - - - - - - -
HIKJKDOL_00275 2.17e-74 yozO - - S - - - Bacterial PH domain
HIKJKDOL_00276 1.91e-42 yozC - - - - - - -
HIKJKDOL_00277 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HIKJKDOL_00278 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
HIKJKDOL_00279 2.26e-210 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
HIKJKDOL_00280 8.78e-300 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HIKJKDOL_00281 4.7e-214 yocS - - S ko:K03453 - ko00000 -transporter
HIKJKDOL_00282 2.13e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HIKJKDOL_00283 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HIKJKDOL_00284 0.0 yojO - - P - - - Von Willebrand factor
HIKJKDOL_00285 1.33e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
HIKJKDOL_00286 8.54e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HIKJKDOL_00287 2.62e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HIKJKDOL_00288 1.13e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
HIKJKDOL_00289 3.69e-142 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HIKJKDOL_00291 5.06e-314 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
HIKJKDOL_00292 2.49e-194 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HIKJKDOL_00293 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
HIKJKDOL_00294 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
HIKJKDOL_00295 1.85e-58 - - - - - - - -
HIKJKDOL_00296 8.13e-208 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
HIKJKDOL_00297 7.43e-107 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
HIKJKDOL_00298 1.95e-14 - - - - - - - -
HIKJKDOL_00299 1.01e-293 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HIKJKDOL_00300 2.05e-86 iolK - - S - - - tautomerase
HIKJKDOL_00301 1.37e-76 yodB - - K - - - transcriptional
HIKJKDOL_00302 1.92e-140 yodC - - C - - - nitroreductase
HIKJKDOL_00303 1.31e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
HIKJKDOL_00304 1.18e-223 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HIKJKDOL_00305 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
HIKJKDOL_00306 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIKJKDOL_00307 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HIKJKDOL_00308 6.38e-168 yodH - - Q - - - Methyltransferase
HIKJKDOL_00309 2.93e-42 yodI - - - - - - -
HIKJKDOL_00310 1.62e-190 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
HIKJKDOL_00311 1.19e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
HIKJKDOL_00312 2.08e-12 - - - - - - - -
HIKJKDOL_00313 1.17e-71 yodL - - S - - - YodL-like
HIKJKDOL_00314 4.02e-138 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HIKJKDOL_00315 5.18e-34 yozD - - S - - - YozD-like protein
HIKJKDOL_00317 3.84e-161 yodN - - - - - - -
HIKJKDOL_00318 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
HIKJKDOL_00319 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
HIKJKDOL_00320 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
HIKJKDOL_00321 9.5e-200 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
HIKJKDOL_00322 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
HIKJKDOL_00323 9.44e-153 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HIKJKDOL_00325 0.0 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HIKJKDOL_00327 8.38e-186 yiiD - - K ko:K06323 - ko00000 acetyltransferase
HIKJKDOL_00328 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
HIKJKDOL_00329 3.04e-59 cgeC - - - ko:K06321 - ko00000 -
HIKJKDOL_00330 5.57e-86 cgeA - - - ko:K06319 - ko00000 -
HIKJKDOL_00331 3.86e-236 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
HIKJKDOL_00332 1.39e-280 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
HIKJKDOL_00333 4.75e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
HIKJKDOL_00334 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HIKJKDOL_00335 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HIKJKDOL_00336 4.14e-94 ypoP - - K - - - transcriptional
HIKJKDOL_00337 7.03e-290 mepA - - V - - - MATE efflux family protein
HIKJKDOL_00338 2.13e-40 ypmT - - S - - - Uncharacterized ympT
HIKJKDOL_00339 1.95e-128 ypmS - - S - - - protein conserved in bacteria
HIKJKDOL_00340 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
HIKJKDOL_00341 3.23e-139 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HIKJKDOL_00342 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
HIKJKDOL_00343 1.04e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HIKJKDOL_00344 1.4e-236 yplP - - K - - - Transcriptional regulator
HIKJKDOL_00345 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
HIKJKDOL_00346 8.12e-144 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HIKJKDOL_00347 9.58e-122 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HIKJKDOL_00348 2.34e-199 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HIKJKDOL_00349 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
HIKJKDOL_00350 3.47e-148 ypjP - - S - - - YpjP-like protein
HIKJKDOL_00351 2.5e-186 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
HIKJKDOL_00352 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
HIKJKDOL_00353 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
HIKJKDOL_00354 9.9e-205 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
HIKJKDOL_00355 2.32e-138 yagB - - S ko:K06950 - ko00000 phosphohydrolase
HIKJKDOL_00356 5.2e-113 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
HIKJKDOL_00357 1.49e-225 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HIKJKDOL_00358 3.67e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HIKJKDOL_00359 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
HIKJKDOL_00360 1.17e-22 degR - - - - - - -
HIKJKDOL_00361 1.5e-40 - - - S - - - Protein of unknown function (DUF2564)
HIKJKDOL_00362 7.99e-41 ypeQ - - S - - - Zinc-finger
HIKJKDOL_00363 1.1e-160 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
HIKJKDOL_00364 3.98e-137 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HIKJKDOL_00365 1.6e-89 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
HIKJKDOL_00366 5.23e-05 - - - - ko:K06429 - ko00000 -
HIKJKDOL_00367 2.26e-213 ypcP - - L - - - 5'3' exonuclease
HIKJKDOL_00368 1.08e-11 - - - - - - - -
HIKJKDOL_00369 4.77e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
HIKJKDOL_00370 0.0 ypbR - - S - - - Dynamin family
HIKJKDOL_00372 5.52e-112 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
HIKJKDOL_00373 1.07e-264 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
HIKJKDOL_00374 8.61e-292 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
HIKJKDOL_00375 1.35e-127 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HIKJKDOL_00376 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HIKJKDOL_00377 5.8e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HIKJKDOL_00378 1.47e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
HIKJKDOL_00379 4.02e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
HIKJKDOL_00380 4.51e-237 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
HIKJKDOL_00381 1.03e-203 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HIKJKDOL_00382 1.88e-175 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIKJKDOL_00383 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
HIKJKDOL_00385 1.16e-285 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HIKJKDOL_00386 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HIKJKDOL_00387 9.4e-128 ypsA - - S - - - Belongs to the UPF0398 family
HIKJKDOL_00388 2.41e-299 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
HIKJKDOL_00389 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HIKJKDOL_00390 2.74e-112 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
HIKJKDOL_00391 1.24e-94 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HIKJKDOL_00392 1.69e-65 yppG - - S - - - YppG-like protein
HIKJKDOL_00393 9.21e-11 - - - S - - - YppF-like protein
HIKJKDOL_00394 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
HIKJKDOL_00397 3.58e-238 yppC - - S - - - Protein of unknown function (DUF2515)
HIKJKDOL_00398 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HIKJKDOL_00399 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HIKJKDOL_00400 1.17e-120 ypoC - - - - - - -
HIKJKDOL_00401 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HIKJKDOL_00402 1.9e-164 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
HIKJKDOL_00403 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
HIKJKDOL_00404 1.07e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HIKJKDOL_00405 1.08e-101 ypmB - - S - - - protein conserved in bacteria
HIKJKDOL_00406 6.21e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
HIKJKDOL_00407 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HIKJKDOL_00408 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HIKJKDOL_00409 7.78e-200 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HIKJKDOL_00410 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HIKJKDOL_00411 4.87e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HIKJKDOL_00412 2.14e-278 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HIKJKDOL_00413 7.01e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
HIKJKDOL_00414 2.21e-165 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
HIKJKDOL_00415 2.52e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
HIKJKDOL_00416 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HIKJKDOL_00417 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
HIKJKDOL_00418 3.04e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HIKJKDOL_00419 2.79e-182 ypjB - - S - - - sporulation protein
HIKJKDOL_00420 3.29e-125 ypjA - - S - - - membrane
HIKJKDOL_00421 3.31e-190 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
HIKJKDOL_00422 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
HIKJKDOL_00423 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
HIKJKDOL_00424 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
HIKJKDOL_00425 7.45e-129 ypiB - - S - - - Belongs to the UPF0302 family
HIKJKDOL_00426 5.27e-299 ypiA - - S - - - COG0457 FOG TPR repeat
HIKJKDOL_00427 9.91e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HIKJKDOL_00428 1.71e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
HIKJKDOL_00429 4.5e-259 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HIKJKDOL_00430 3.82e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HIKJKDOL_00431 1.09e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HIKJKDOL_00432 3.7e-149 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
HIKJKDOL_00433 1.2e-144 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
HIKJKDOL_00434 8.28e-228 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HIKJKDOL_00435 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HIKJKDOL_00436 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HIKJKDOL_00437 8.48e-265 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HIKJKDOL_00438 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HIKJKDOL_00439 3.69e-183 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
HIKJKDOL_00440 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HIKJKDOL_00441 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HIKJKDOL_00442 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HIKJKDOL_00443 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HIKJKDOL_00444 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HIKJKDOL_00445 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
HIKJKDOL_00446 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HIKJKDOL_00447 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HIKJKDOL_00448 9.07e-178 yphF - - - - - - -
HIKJKDOL_00449 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
HIKJKDOL_00450 2.01e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HIKJKDOL_00451 4.77e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HIKJKDOL_00452 8.69e-40 ypzH - - - - - - -
HIKJKDOL_00453 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
HIKJKDOL_00454 2.73e-134 yphA - - - - - - -
HIKJKDOL_00455 1.13e-11 - - - S - - - YpzI-like protein
HIKJKDOL_00456 8.41e-238 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HIKJKDOL_00457 9.5e-263 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HIKJKDOL_00458 1.73e-147 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HIKJKDOL_00459 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
HIKJKDOL_00460 4.63e-144 ypfA - - M - - - Flagellar protein YcgR
HIKJKDOL_00461 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
HIKJKDOL_00462 4.88e-208 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
HIKJKDOL_00463 4.33e-154 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
HIKJKDOL_00464 1.62e-227 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
HIKJKDOL_00465 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HIKJKDOL_00466 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HIKJKDOL_00467 5.05e-187 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HIKJKDOL_00468 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
HIKJKDOL_00469 5.04e-148 ypbE - - M - - - Lysin motif
HIKJKDOL_00470 6.13e-129 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
HIKJKDOL_00471 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
HIKJKDOL_00472 5.67e-258 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
HIKJKDOL_00473 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
HIKJKDOL_00474 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HIKJKDOL_00475 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIKJKDOL_00476 1.95e-173 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HIKJKDOL_00477 1.95e-250 rsiX - - - - - - -
HIKJKDOL_00478 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HIKJKDOL_00479 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HIKJKDOL_00480 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIKJKDOL_00481 2.22e-277 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HIKJKDOL_00482 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
HIKJKDOL_00483 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HIKJKDOL_00484 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HIKJKDOL_00485 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
HIKJKDOL_00486 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
HIKJKDOL_00487 1.18e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HIKJKDOL_00488 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
HIKJKDOL_00489 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HIKJKDOL_00490 1.09e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HIKJKDOL_00491 2.51e-120 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
HIKJKDOL_00492 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIKJKDOL_00493 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HIKJKDOL_00494 1.27e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HIKJKDOL_00495 1.24e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
HIKJKDOL_00496 1.19e-259 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HIKJKDOL_00497 5.98e-72 ypuD - - - - - - -
HIKJKDOL_00498 3.39e-132 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HIKJKDOL_00499 1.28e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
HIKJKDOL_00500 5.56e-17 - - - S - - - SNARE associated Golgi protein
HIKJKDOL_00504 2.61e-34 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HIKJKDOL_00509 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HIKJKDOL_00510 3.12e-192 ypuA - - S - - - Secreted protein
HIKJKDOL_00511 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HIKJKDOL_00512 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
HIKJKDOL_00513 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
HIKJKDOL_00514 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
HIKJKDOL_00515 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
HIKJKDOL_00516 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
HIKJKDOL_00517 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
HIKJKDOL_00518 5.72e-144 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
HIKJKDOL_00519 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIKJKDOL_00520 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HIKJKDOL_00521 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
HIKJKDOL_00522 2.89e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HIKJKDOL_00523 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HIKJKDOL_00524 6.8e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
HIKJKDOL_00525 3.91e-214 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
HIKJKDOL_00526 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
HIKJKDOL_00527 2.64e-103 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HIKJKDOL_00528 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HIKJKDOL_00529 3.73e-44 yqkK - - - - - - -
HIKJKDOL_00530 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
HIKJKDOL_00531 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
HIKJKDOL_00532 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
HIKJKDOL_00533 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
HIKJKDOL_00534 3.18e-77 ansR - - K - - - Transcriptional regulator
HIKJKDOL_00535 2.62e-283 yqxK - - L - - - DNA helicase
HIKJKDOL_00536 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
HIKJKDOL_00537 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
HIKJKDOL_00538 2.65e-217 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
HIKJKDOL_00539 1.78e-29 yqkE - - S - - - Protein of unknown function (DUF3886)
HIKJKDOL_00540 4.29e-227 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HIKJKDOL_00541 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
HIKJKDOL_00542 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
HIKJKDOL_00543 2.89e-251 yqkA - - K - - - GrpB protein
HIKJKDOL_00544 5.51e-79 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
HIKJKDOL_00545 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
HIKJKDOL_00546 1.87e-65 yqiX - - S - - - YolD-like protein
HIKJKDOL_00547 1.46e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HIKJKDOL_00549 6.83e-288 yqjV - - G - - - Major Facilitator Superfamily
HIKJKDOL_00551 7.43e-93 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIKJKDOL_00552 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HIKJKDOL_00553 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
HIKJKDOL_00554 6.89e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HIKJKDOL_00555 3.14e-227 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HIKJKDOL_00556 1.13e-188 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIKJKDOL_00557 0.0 rocB - - E - - - arginine degradation protein
HIKJKDOL_00558 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HIKJKDOL_00559 6.4e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HIKJKDOL_00560 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HIKJKDOL_00561 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HIKJKDOL_00562 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HIKJKDOL_00563 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HIKJKDOL_00564 7.8e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HIKJKDOL_00565 1.77e-32 yqzJ - - - - - - -
HIKJKDOL_00566 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HIKJKDOL_00567 6.93e-181 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
HIKJKDOL_00568 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
HIKJKDOL_00569 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HIKJKDOL_00570 7.75e-94 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
HIKJKDOL_00572 2.41e-128 yqjB - - S - - - protein conserved in bacteria
HIKJKDOL_00573 1.55e-224 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
HIKJKDOL_00574 5.2e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HIKJKDOL_00575 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HIKJKDOL_00576 1.18e-174 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HIKJKDOL_00577 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
HIKJKDOL_00578 7.01e-213 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HIKJKDOL_00579 7.27e-266 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
HIKJKDOL_00580 1.5e-193 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
HIKJKDOL_00581 6.24e-287 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HIKJKDOL_00582 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HIKJKDOL_00583 1.92e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HIKJKDOL_00584 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HIKJKDOL_00585 1.18e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
HIKJKDOL_00586 2.24e-261 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HIKJKDOL_00587 8.64e-199 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
HIKJKDOL_00588 0.0 bkdR - - KT - - - Transcriptional regulator
HIKJKDOL_00589 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
HIKJKDOL_00590 3.84e-203 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HIKJKDOL_00591 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
HIKJKDOL_00592 1.07e-263 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HIKJKDOL_00593 6.02e-269 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
HIKJKDOL_00594 4.16e-200 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
HIKJKDOL_00595 5.7e-281 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HIKJKDOL_00596 3.68e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HIKJKDOL_00597 5.67e-139 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
HIKJKDOL_00598 2.26e-37 - - - - - - - -
HIKJKDOL_00599 1.77e-276 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HIKJKDOL_00601 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HIKJKDOL_00602 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
HIKJKDOL_00603 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HIKJKDOL_00604 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HIKJKDOL_00605 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
HIKJKDOL_00606 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HIKJKDOL_00607 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HIKJKDOL_00608 3.81e-50 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIKJKDOL_00609 2.05e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIKJKDOL_00610 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HIKJKDOL_00611 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HIKJKDOL_00612 1.65e-88 yqhY - - S - - - protein conserved in bacteria
HIKJKDOL_00613 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HIKJKDOL_00614 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HIKJKDOL_00615 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
HIKJKDOL_00616 1.08e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
HIKJKDOL_00617 2.58e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
HIKJKDOL_00618 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
HIKJKDOL_00619 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
HIKJKDOL_00620 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
HIKJKDOL_00621 5.69e-111 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
HIKJKDOL_00622 5.79e-217 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
HIKJKDOL_00623 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
HIKJKDOL_00624 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HIKJKDOL_00625 2.11e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
HIKJKDOL_00626 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
HIKJKDOL_00627 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
HIKJKDOL_00628 1.48e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
HIKJKDOL_00629 5.18e-81 yqhP - - - - - - -
HIKJKDOL_00630 3.33e-208 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HIKJKDOL_00631 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HIKJKDOL_00632 9.17e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HIKJKDOL_00633 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
HIKJKDOL_00634 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HIKJKDOL_00635 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HIKJKDOL_00636 1.11e-260 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
HIKJKDOL_00637 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
HIKJKDOL_00638 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
HIKJKDOL_00639 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
HIKJKDOL_00640 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
HIKJKDOL_00641 9e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
HIKJKDOL_00642 4.27e-97 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
HIKJKDOL_00643 2.29e-155 yqxM - - - ko:K19433 - ko00000 -
HIKJKDOL_00644 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
HIKJKDOL_00645 3.33e-35 yqzE - - S - - - YqzE-like protein
HIKJKDOL_00646 3.78e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
HIKJKDOL_00647 1.18e-45 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
HIKJKDOL_00648 2.95e-77 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
HIKJKDOL_00649 4.62e-92 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
HIKJKDOL_00650 4.39e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
HIKJKDOL_00651 8.73e-219 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
HIKJKDOL_00652 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HIKJKDOL_00653 3.73e-09 yhcV - - S - - - COG0517 FOG CBS domain
HIKJKDOL_00654 1.51e-233 yqxL - - P - - - Mg2 transporter protein
HIKJKDOL_00655 5.77e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HIKJKDOL_00656 7.14e-192 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HIKJKDOL_00658 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
HIKJKDOL_00659 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
HIKJKDOL_00660 3.2e-157 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
HIKJKDOL_00661 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
HIKJKDOL_00662 7.34e-66 yqgV - - S - - - Thiamine-binding protein
HIKJKDOL_00663 5.65e-258 yqgU - - - - - - -
HIKJKDOL_00664 1.06e-283 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
HIKJKDOL_00665 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HIKJKDOL_00666 2.81e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HIKJKDOL_00667 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
HIKJKDOL_00668 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
HIKJKDOL_00669 3.38e-14 yqgO - - - - - - -
HIKJKDOL_00670 3.8e-135 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HIKJKDOL_00671 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HIKJKDOL_00672 2.81e-257 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
HIKJKDOL_00674 2.81e-67 yqzD - - - - - - -
HIKJKDOL_00675 1.09e-93 yqzC - - S - - - YceG-like family
HIKJKDOL_00676 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HIKJKDOL_00677 2.4e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HIKJKDOL_00678 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
HIKJKDOL_00679 7.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HIKJKDOL_00680 3.71e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HIKJKDOL_00681 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
HIKJKDOL_00682 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
HIKJKDOL_00683 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
HIKJKDOL_00684 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
HIKJKDOL_00685 1.58e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
HIKJKDOL_00686 1.64e-62 yqfZ - - M ko:K06417 - ko00000 LysM domain
HIKJKDOL_00687 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HIKJKDOL_00688 2.04e-81 yqfX - - S - - - membrane
HIKJKDOL_00689 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
HIKJKDOL_00690 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
HIKJKDOL_00691 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HIKJKDOL_00692 1.74e-48 yqfT - - S - - - Protein of unknown function (DUF2624)
HIKJKDOL_00693 4.23e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HIKJKDOL_00694 1.28e-309 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HIKJKDOL_00695 3.36e-49 yqfQ - - S - - - YqfQ-like protein
HIKJKDOL_00696 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HIKJKDOL_00697 2.97e-266 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HIKJKDOL_00698 4.66e-148 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HIKJKDOL_00699 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
HIKJKDOL_00700 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HIKJKDOL_00701 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HIKJKDOL_00702 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
HIKJKDOL_00703 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HIKJKDOL_00704 3.29e-144 ccpN - - K - - - CBS domain
HIKJKDOL_00705 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HIKJKDOL_00706 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HIKJKDOL_00707 5.26e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HIKJKDOL_00708 5.29e-27 - - - S - - - YqzL-like protein
HIKJKDOL_00709 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HIKJKDOL_00710 2.73e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HIKJKDOL_00711 4.75e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HIKJKDOL_00712 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HIKJKDOL_00713 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
HIKJKDOL_00715 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
HIKJKDOL_00716 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
HIKJKDOL_00717 2.07e-60 yqfC - - S - - - sporulation protein YqfC
HIKJKDOL_00718 6.04e-61 yqfB - - - - - - -
HIKJKDOL_00719 4.35e-192 yqfA - - S - - - UPF0365 protein
HIKJKDOL_00720 1.08e-289 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
HIKJKDOL_00721 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
HIKJKDOL_00722 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HIKJKDOL_00723 1.4e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
HIKJKDOL_00724 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
HIKJKDOL_00725 1.68e-179 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HIKJKDOL_00726 9.34e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
HIKJKDOL_00727 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HIKJKDOL_00728 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HIKJKDOL_00729 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HIKJKDOL_00730 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HIKJKDOL_00731 2.9e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
HIKJKDOL_00732 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HIKJKDOL_00733 7.06e-70 yqxA - - S - - - Protein of unknown function (DUF3679)
HIKJKDOL_00734 1.58e-282 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
HIKJKDOL_00735 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HIKJKDOL_00736 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HIKJKDOL_00737 1.16e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HIKJKDOL_00738 2.36e-22 - - - S - - - YqzM-like protein
HIKJKDOL_00739 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HIKJKDOL_00740 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HIKJKDOL_00741 6.65e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
HIKJKDOL_00742 1.1e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIKJKDOL_00743 9.8e-179 yqeM - - Q - - - Methyltransferase
HIKJKDOL_00744 1.14e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HIKJKDOL_00745 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
HIKJKDOL_00746 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HIKJKDOL_00747 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
HIKJKDOL_00748 4.01e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HIKJKDOL_00749 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HIKJKDOL_00750 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
HIKJKDOL_00752 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
HIKJKDOL_00753 8.96e-172 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
HIKJKDOL_00754 3.27e-135 yqeD - - S - - - SNARE associated Golgi protein
HIKJKDOL_00755 1.26e-215 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
HIKJKDOL_00756 2.21e-169 - - - - - - - -
HIKJKDOL_00757 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
HIKJKDOL_00758 7.53e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIKJKDOL_00759 4.56e-144 tetR3 - - K ko:K18476 - ko00000,ko00002,ko03000 Transcriptional regulator
HIKJKDOL_00760 1.06e-272 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 Multidrug transporter MatE
HIKJKDOL_00761 3.1e-208 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
HIKJKDOL_00762 5.52e-155 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
HIKJKDOL_00763 2.63e-48 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
HIKJKDOL_00764 1.2e-262 yrkH - - P - - - Rhodanese Homology Domain
HIKJKDOL_00765 3.79e-125 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
HIKJKDOL_00766 1.96e-108 yrkE - - O - - - DsrE/DsrF/DrsH-like family
HIKJKDOL_00767 4.38e-52 yrkD - - S - - - protein conserved in bacteria
HIKJKDOL_00768 6.08e-136 yrkC - - G - - - Cupin domain
HIKJKDOL_00769 1.62e-190 bltR - - K - - - helix_turn_helix, mercury resistance
HIKJKDOL_00770 1.08e-268 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
HIKJKDOL_00771 7.23e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
HIKJKDOL_00772 1.52e-299 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HIKJKDOL_00773 2.45e-23 - - - S - - - YrzO-like protein
HIKJKDOL_00774 8.49e-217 yrdR - - EG - - - EamA-like transporter family
HIKJKDOL_00775 9.87e-204 - - - K - - - Transcriptional regulator
HIKJKDOL_00776 6.09e-254 trkA - - P ko:K07222 - ko00000 Oxidoreductase
HIKJKDOL_00777 2.05e-204 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
HIKJKDOL_00778 1.75e-87 yodA - - S - - - tautomerase
HIKJKDOL_00779 2.43e-208 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
HIKJKDOL_00780 1.43e-291 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HIKJKDOL_00781 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
HIKJKDOL_00782 3.26e-176 azlC - - E - - - AzlC protein
HIKJKDOL_00783 4.82e-103 bkdR - - K - - - helix_turn_helix ASNC type
HIKJKDOL_00784 2.76e-55 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
HIKJKDOL_00785 4.27e-132 yrdC - - Q - - - Isochorismatase family
HIKJKDOL_00786 3.24e-75 - - - S - - - Protein of unknown function (DUF2568)
HIKJKDOL_00787 5.77e-118 yrdA - - S - - - DinB family
HIKJKDOL_00788 3.62e-213 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
HIKJKDOL_00789 4.23e-246 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HIKJKDOL_00790 1.02e-189 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HIKJKDOL_00791 5.63e-161 yrpD - - S - - - Domain of unknown function, YrpD
HIKJKDOL_00793 3.78e-169 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HIKJKDOL_00794 6.39e-124 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HIKJKDOL_00795 4.9e-239 yrpG - - C - - - Aldo/keto reductase family
HIKJKDOL_00796 1.45e-283 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HIKJKDOL_00797 2.97e-210 yraN - - K - - - Transcriptional regulator
HIKJKDOL_00798 5.95e-263 yraM - - S - - - PrpF protein
HIKJKDOL_00800 5.73e-202 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HIKJKDOL_00801 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIKJKDOL_00802 4.9e-200 - - - S - - - Alpha beta hydrolase
HIKJKDOL_00803 6.61e-80 - - - T - - - sh3 domain protein
HIKJKDOL_00804 2.92e-81 - - - T - - - sh3 domain protein
HIKJKDOL_00805 6.62e-87 - - - E - - - Glyoxalase-like domain
HIKJKDOL_00806 4.19e-50 yraG - - - ko:K06440 - ko00000 -
HIKJKDOL_00807 9.61e-84 yraF - - M - - - Spore coat protein
HIKJKDOL_00808 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HIKJKDOL_00809 1.05e-36 yraE - - - ko:K06440 - ko00000 -
HIKJKDOL_00810 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
HIKJKDOL_00811 3.17e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
HIKJKDOL_00812 3.03e-40 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
HIKJKDOL_00813 8.68e-256 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
HIKJKDOL_00814 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
HIKJKDOL_00815 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HIKJKDOL_00816 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HIKJKDOL_00817 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HIKJKDOL_00818 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
HIKJKDOL_00819 2.66e-97 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HIKJKDOL_00820 0.0 levR - - K - - - PTS system fructose IIA component
HIKJKDOL_00821 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HIKJKDOL_00822 5.63e-137 yrhP - - E - - - LysE type translocator
HIKJKDOL_00823 1.98e-192 yrhO - - K - - - Archaeal transcriptional regulator TrmB
HIKJKDOL_00824 8.2e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HIKJKDOL_00825 7.4e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
HIKJKDOL_00826 0.0 oatA - - I - - - Acyltransferase family
HIKJKDOL_00827 2.11e-26 yrhK - - S - - - YrhK-like protein
HIKJKDOL_00829 3.5e-12 - - - S - - - cell adhesion involved in biofilm formation
HIKJKDOL_00831 1.25e-105 yodQ 3.5.1.16 - E ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
HIKJKDOL_00832 3.16e-122 - - - EF - - - ATP-grasp domain
HIKJKDOL_00833 6.2e-227 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Aromatic amino acid lyase
HIKJKDOL_00834 2.89e-54 - - - I - - - COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HIKJKDOL_00835 3.8e-121 - - - Q - - - TIGRFAM amino acid adenylation domain
HIKJKDOL_00836 2.25e-78 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HIKJKDOL_00837 5.35e-80 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HIKJKDOL_00838 6.6e-147 - - - S ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HIKJKDOL_00839 2.31e-148 - 5.1.3.2, 5.1.3.20, 5.1.3.7 - GM ko:K01784,ko:K02473,ko:K03274 ko00052,ko00520,ko00540,ko01100,map00052,map00520,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 NmrA-like family
HIKJKDOL_00840 7.54e-211 - 1.1.1.136, 1.1.1.336 - C ko:K02472,ko:K02474,ko:K13015 ko00520,ko05111,map00520,map05111 ko00000,ko00001,ko01000,ko01005 PFAM UDP-glucose GDP-mannose dehydrogenase
HIKJKDOL_00841 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
HIKJKDOL_00842 3.22e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
HIKJKDOL_00843 6.1e-124 yrhH - - Q - - - methyltransferase
HIKJKDOL_00844 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
HIKJKDOL_00846 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
HIKJKDOL_00847 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
HIKJKDOL_00848 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
HIKJKDOL_00849 4.26e-103 yrhD - - S - - - Protein of unknown function (DUF1641)
HIKJKDOL_00850 6.93e-49 yrhC - - S - - - YrhC-like protein
HIKJKDOL_00851 2.86e-267 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HIKJKDOL_00852 4.96e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
HIKJKDOL_00853 1.14e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HIKJKDOL_00854 9.86e-153 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
HIKJKDOL_00855 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
HIKJKDOL_00856 1.65e-101 yrrS - - S - - - Protein of unknown function (DUF1510)
HIKJKDOL_00857 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
HIKJKDOL_00858 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HIKJKDOL_00859 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HIKJKDOL_00860 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
HIKJKDOL_00861 1.09e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
HIKJKDOL_00862 1.4e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
HIKJKDOL_00863 1.77e-240 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HIKJKDOL_00864 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
HIKJKDOL_00865 3.71e-91 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HIKJKDOL_00866 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
HIKJKDOL_00867 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HIKJKDOL_00868 3.07e-242 yrrI - - S - - - AI-2E family transporter
HIKJKDOL_00869 9.37e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HIKJKDOL_00870 5.2e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HIKJKDOL_00871 9.28e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HIKJKDOL_00872 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HIKJKDOL_00873 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
HIKJKDOL_00874 8.4e-42 yrzR - - - - - - -
HIKJKDOL_00875 9.34e-104 yrrD - - S - - - protein conserved in bacteria
HIKJKDOL_00876 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HIKJKDOL_00877 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
HIKJKDOL_00878 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HIKJKDOL_00879 1.09e-271 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HIKJKDOL_00880 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
HIKJKDOL_00881 3.36e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HIKJKDOL_00882 3.96e-177 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HIKJKDOL_00883 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HIKJKDOL_00884 3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HIKJKDOL_00886 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
HIKJKDOL_00887 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HIKJKDOL_00888 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HIKJKDOL_00889 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HIKJKDOL_00890 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HIKJKDOL_00891 3.06e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
HIKJKDOL_00892 6.51e-114 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
HIKJKDOL_00893 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HIKJKDOL_00894 1.93e-65 yrzD - - S - - - Post-transcriptional regulator
HIKJKDOL_00895 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HIKJKDOL_00896 2.89e-143 yrbG - - S - - - membrane
HIKJKDOL_00897 1.46e-96 yrzE - - S - - - Protein of unknown function (DUF3792)
HIKJKDOL_00898 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
HIKJKDOL_00899 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HIKJKDOL_00900 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HIKJKDOL_00901 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
HIKJKDOL_00902 3.72e-238 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HIKJKDOL_00903 9.49e-136 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HIKJKDOL_00904 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
HIKJKDOL_00905 0.0 csbX - - EGP - - - the major facilitator superfamily
HIKJKDOL_00906 1.13e-247 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
HIKJKDOL_00907 2.32e-152 yrzF - - T - - - serine threonine protein kinase
HIKJKDOL_00909 5.2e-67 - - - S - - - Family of unknown function (DUF5412)
HIKJKDOL_00910 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
HIKJKDOL_00911 1.67e-162 yebC - - K - - - transcriptional regulatory protein
HIKJKDOL_00912 1.47e-69 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HIKJKDOL_00913 2.43e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
HIKJKDOL_00914 3.23e-272 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HIKJKDOL_00915 3.72e-204 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
HIKJKDOL_00916 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
HIKJKDOL_00917 1.37e-289 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HIKJKDOL_00918 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
HIKJKDOL_00919 1.43e-208 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
HIKJKDOL_00920 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
HIKJKDOL_00921 9.66e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HIKJKDOL_00922 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
HIKJKDOL_00923 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HIKJKDOL_00924 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
HIKJKDOL_00925 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HIKJKDOL_00926 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
HIKJKDOL_00927 8.69e-186 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
HIKJKDOL_00928 6.84e-185 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
HIKJKDOL_00929 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HIKJKDOL_00930 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
HIKJKDOL_00931 1.91e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HIKJKDOL_00932 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
HIKJKDOL_00933 2.4e-162 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
HIKJKDOL_00934 7.06e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
HIKJKDOL_00935 1.74e-210 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
HIKJKDOL_00936 5.33e-163 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HIKJKDOL_00937 2.22e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HIKJKDOL_00938 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HIKJKDOL_00939 1.53e-35 - - - - - - - -
HIKJKDOL_00940 4.82e-252 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HIKJKDOL_00941 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
HIKJKDOL_00942 1.05e-313 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
HIKJKDOL_00943 6.39e-234 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
HIKJKDOL_00944 2.49e-184 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
HIKJKDOL_00945 1.8e-219 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HIKJKDOL_00946 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
HIKJKDOL_00947 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HIKJKDOL_00948 8.23e-117 ysxD - - - - - - -
HIKJKDOL_00949 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HIKJKDOL_00950 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HIKJKDOL_00951 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
HIKJKDOL_00952 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HIKJKDOL_00953 8.87e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HIKJKDOL_00954 2.73e-240 ysoA - - H - - - Tetratricopeptide repeat
HIKJKDOL_00955 5.35e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HIKJKDOL_00956 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HIKJKDOL_00957 1.06e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HIKJKDOL_00958 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HIKJKDOL_00959 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HIKJKDOL_00960 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HIKJKDOL_00961 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HIKJKDOL_00963 3.32e-107 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
HIKJKDOL_00964 1.01e-184 ysnF - - S - - - protein conserved in bacteria
HIKJKDOL_00966 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
HIKJKDOL_00967 1.06e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HIKJKDOL_00968 3.53e-171 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HIKJKDOL_00969 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
HIKJKDOL_00970 4.49e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HIKJKDOL_00971 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
HIKJKDOL_00972 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
HIKJKDOL_00973 2.65e-102 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
HIKJKDOL_00974 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
HIKJKDOL_00975 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
HIKJKDOL_00976 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
HIKJKDOL_00977 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
HIKJKDOL_00978 1.61e-274 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HIKJKDOL_00979 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HIKJKDOL_00980 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HIKJKDOL_00981 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
HIKJKDOL_00983 1.23e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
HIKJKDOL_00984 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
HIKJKDOL_00985 2.2e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
HIKJKDOL_00986 1.21e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
HIKJKDOL_00987 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HIKJKDOL_00988 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
HIKJKDOL_00989 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HIKJKDOL_00990 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
HIKJKDOL_00991 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
HIKJKDOL_00992 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HIKJKDOL_00993 6.77e-219 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIKJKDOL_00994 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HIKJKDOL_00995 3e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HIKJKDOL_00996 3.13e-171 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIKJKDOL_00997 4.37e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
HIKJKDOL_00998 1.07e-261 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
HIKJKDOL_00999 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
HIKJKDOL_01000 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
HIKJKDOL_01001 1.26e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
HIKJKDOL_01002 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
HIKJKDOL_01003 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
HIKJKDOL_01004 2.47e-189 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
HIKJKDOL_01005 1.94e-218 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
HIKJKDOL_01006 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
HIKJKDOL_01007 3.05e-281 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HIKJKDOL_01008 6.06e-187 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
HIKJKDOL_01009 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HIKJKDOL_01010 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
HIKJKDOL_01011 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
HIKJKDOL_01012 4.04e-241 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
HIKJKDOL_01013 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
HIKJKDOL_01014 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
HIKJKDOL_01015 1.27e-59 ysdA - - S - - - Membrane
HIKJKDOL_01016 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HIKJKDOL_01017 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HIKJKDOL_01018 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HIKJKDOL_01020 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HIKJKDOL_01021 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HIKJKDOL_01022 2.9e-168 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
HIKJKDOL_01023 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HIKJKDOL_01024 2.07e-191 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
HIKJKDOL_01025 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HIKJKDOL_01026 5.98e-206 ytxC - - S - - - YtxC-like family
HIKJKDOL_01027 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
HIKJKDOL_01028 1.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HIKJKDOL_01029 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
HIKJKDOL_01030 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HIKJKDOL_01031 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HIKJKDOL_01032 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HIKJKDOL_01033 9.85e-88 ytcD - - K - - - Transcriptional regulator
HIKJKDOL_01034 5.44e-260 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
HIKJKDOL_01035 4.54e-205 ytbE - - S - - - reductase
HIKJKDOL_01036 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HIKJKDOL_01037 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
HIKJKDOL_01038 7e-203 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HIKJKDOL_01039 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HIKJKDOL_01040 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
HIKJKDOL_01041 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIKJKDOL_01042 2.55e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
HIKJKDOL_01043 2.28e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
HIKJKDOL_01044 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HIKJKDOL_01045 9.38e-95 ytwI - - S - - - membrane
HIKJKDOL_01046 2.24e-244 ytvI - - S - - - sporulation integral membrane protein YtvI
HIKJKDOL_01047 4.68e-82 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
HIKJKDOL_01048 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HIKJKDOL_01049 6.6e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HIKJKDOL_01050 6.63e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HIKJKDOL_01051 1.35e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HIKJKDOL_01052 6.01e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
HIKJKDOL_01053 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HIKJKDOL_01054 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
HIKJKDOL_01055 5.12e-112 ytrI - - - - - - -
HIKJKDOL_01056 1.15e-39 - - - - - - - -
HIKJKDOL_01057 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
HIKJKDOL_01058 2.15e-63 ytpI - - S - - - YtpI-like protein
HIKJKDOL_01059 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
HIKJKDOL_01060 2.24e-206 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
HIKJKDOL_01061 2.09e-306 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
HIKJKDOL_01062 1.69e-166 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
HIKJKDOL_01063 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIKJKDOL_01064 5.26e-63 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
HIKJKDOL_01065 1.52e-237 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIKJKDOL_01066 6.61e-183 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HIKJKDOL_01067 4.76e-155 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HIKJKDOL_01068 1.66e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HIKJKDOL_01069 4.01e-194 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HIKJKDOL_01070 3.18e-195 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HIKJKDOL_01071 8.39e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HIKJKDOL_01072 4.99e-223 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
HIKJKDOL_01073 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
HIKJKDOL_01074 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIKJKDOL_01076 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HIKJKDOL_01077 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HIKJKDOL_01078 8.14e-115 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
HIKJKDOL_01079 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIKJKDOL_01080 3.78e-224 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
HIKJKDOL_01081 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HIKJKDOL_01082 2.24e-96 ytfJ - - S - - - Sporulation protein YtfJ
HIKJKDOL_01083 5.03e-150 ytfI - - S - - - Protein of unknown function (DUF2953)
HIKJKDOL_01084 7.05e-113 yteJ - - S - - - RDD family
HIKJKDOL_01085 2.49e-232 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
HIKJKDOL_01086 2.92e-190 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HIKJKDOL_01087 0.0 ytcJ - - S - - - amidohydrolase
HIKJKDOL_01088 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HIKJKDOL_01089 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
HIKJKDOL_01090 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HIKJKDOL_01091 1.22e-269 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HIKJKDOL_01092 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HIKJKDOL_01093 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HIKJKDOL_01094 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HIKJKDOL_01095 2.94e-142 yttP - - K - - - Transcriptional regulator
HIKJKDOL_01096 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HIKJKDOL_01097 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
HIKJKDOL_01098 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HIKJKDOL_01100 6.47e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HIKJKDOL_01101 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HIKJKDOL_01102 2.43e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HIKJKDOL_01103 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
HIKJKDOL_01104 6.51e-293 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
HIKJKDOL_01105 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
HIKJKDOL_01106 1.18e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
HIKJKDOL_01107 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HIKJKDOL_01108 3.11e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HIKJKDOL_01109 1.57e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
HIKJKDOL_01110 2.15e-22 ytxH - - S - - - COG4980 Gas vesicle protein
HIKJKDOL_01111 3.8e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HIKJKDOL_01112 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HIKJKDOL_01113 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HIKJKDOL_01114 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HIKJKDOL_01115 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
HIKJKDOL_01116 3.17e-75 ytpP - - CO - - - Thioredoxin
HIKJKDOL_01117 9.97e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
HIKJKDOL_01118 9.11e-262 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
HIKJKDOL_01119 6.75e-67 ytzB - - S - - - small secreted protein
HIKJKDOL_01120 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
HIKJKDOL_01121 4.33e-190 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HIKJKDOL_01122 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HIKJKDOL_01123 9.51e-61 ytzH - - S - - - YtzH-like protein
HIKJKDOL_01124 8.67e-192 ytmP - - M - - - Phosphotransferase
HIKJKDOL_01125 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HIKJKDOL_01126 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HIKJKDOL_01127 4.92e-212 ytlQ - - - - - - -
HIKJKDOL_01128 7.71e-133 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HIKJKDOL_01129 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HIKJKDOL_01130 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
HIKJKDOL_01131 1.73e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
HIKJKDOL_01132 3.15e-258 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
HIKJKDOL_01133 3.98e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HIKJKDOL_01134 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
HIKJKDOL_01135 9.04e-171 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HIKJKDOL_01136 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HIKJKDOL_01137 2.34e-292 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
HIKJKDOL_01138 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
HIKJKDOL_01139 2.14e-36 yteV - - S - - - Sporulation protein Cse60
HIKJKDOL_01140 1.97e-152 yteU - - S - - - Integral membrane protein
HIKJKDOL_01141 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HIKJKDOL_01142 5.81e-95 yteS - - G - - - transport
HIKJKDOL_01143 2.23e-286 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HIKJKDOL_01144 2.27e-221 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
HIKJKDOL_01145 0.0 ytdP - - K - - - Transcriptional regulator
HIKJKDOL_01146 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
HIKJKDOL_01147 1.02e-191 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HIKJKDOL_01148 2.48e-175 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
HIKJKDOL_01149 4.02e-282 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HIKJKDOL_01150 3.08e-242 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HIKJKDOL_01151 7.69e-159 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HIKJKDOL_01152 3.15e-276 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HIKJKDOL_01153 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HIKJKDOL_01154 1.92e-180 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HIKJKDOL_01155 1.87e-218 - - - S - - - Acetyl xylan esterase (AXE1)
HIKJKDOL_01156 2.64e-243 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HIKJKDOL_01157 7.71e-314 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HIKJKDOL_01158 4.75e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HIKJKDOL_01159 3.63e-184 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
HIKJKDOL_01160 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HIKJKDOL_01161 1.22e-68 ytwF - - P - - - Sulfurtransferase
HIKJKDOL_01162 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HIKJKDOL_01163 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
HIKJKDOL_01164 3.82e-183 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HIKJKDOL_01165 2.34e-266 yttB - - EGP - - - Major facilitator superfamily
HIKJKDOL_01166 2.67e-76 yttA - - S - - - Pfam Transposase IS66
HIKJKDOL_01167 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
HIKJKDOL_01168 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
HIKJKDOL_01169 1.07e-237 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
HIKJKDOL_01170 7.76e-168 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIKJKDOL_01171 9.81e-297 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HIKJKDOL_01172 1.02e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HIKJKDOL_01173 1.07e-189 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
HIKJKDOL_01174 1.78e-217 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HIKJKDOL_01175 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HIKJKDOL_01176 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
HIKJKDOL_01178 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
HIKJKDOL_01179 4.06e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
HIKJKDOL_01180 6.76e-137 ytqB - - J - - - Putative rRNA methylase
HIKJKDOL_01181 2.78e-275 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
HIKJKDOL_01182 6.67e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
HIKJKDOL_01183 2.39e-87 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HIKJKDOL_01184 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HIKJKDOL_01185 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HIKJKDOL_01186 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HIKJKDOL_01187 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HIKJKDOL_01188 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
HIKJKDOL_01189 6.67e-191 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HIKJKDOL_01190 2.77e-242 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HIKJKDOL_01191 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HIKJKDOL_01192 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HIKJKDOL_01193 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HIKJKDOL_01194 1.59e-81 ytkC - - S - - - Bacteriophage holin family
HIKJKDOL_01195 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HIKJKDOL_01197 6.79e-95 ytkA - - S - - - YtkA-like
HIKJKDOL_01198 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HIKJKDOL_01199 1.27e-133 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HIKJKDOL_01200 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HIKJKDOL_01201 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
HIKJKDOL_01202 2.83e-239 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HIKJKDOL_01203 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
HIKJKDOL_01204 9.65e-194 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HIKJKDOL_01205 3.69e-296 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HIKJKDOL_01206 1.83e-180 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HIKJKDOL_01207 1.13e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HIKJKDOL_01208 7.07e-273 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HIKJKDOL_01209 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HIKJKDOL_01210 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HIKJKDOL_01211 5.09e-199 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HIKJKDOL_01212 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HIKJKDOL_01213 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
HIKJKDOL_01214 8.68e-169 yteA - - T - - - COG1734 DnaK suppressor protein
HIKJKDOL_01215 1.7e-196 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
HIKJKDOL_01216 2.03e-310 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HIKJKDOL_01217 3.15e-230 ytcB - - M - - - NAD-dependent epimerase dehydratase
HIKJKDOL_01218 3.7e-300 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
HIKJKDOL_01220 1.7e-263 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
HIKJKDOL_01221 1.75e-276 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
HIKJKDOL_01222 9.43e-263 cotI - - S ko:K06331 - ko00000 Spore coat protein
HIKJKDOL_01223 1.97e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
HIKJKDOL_01224 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HIKJKDOL_01225 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
HIKJKDOL_01226 1.58e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
HIKJKDOL_01227 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HIKJKDOL_01228 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HIKJKDOL_01250 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HIKJKDOL_01251 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
HIKJKDOL_01252 1.64e-120 - - - M - - - FR47-like protein
HIKJKDOL_01253 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
HIKJKDOL_01254 1.68e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
HIKJKDOL_01255 1.95e-109 yuaE - - S - - - DinB superfamily
HIKJKDOL_01256 6.78e-136 yuaD - - - - - - -
HIKJKDOL_01257 2.46e-291 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
HIKJKDOL_01258 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HIKJKDOL_01259 1.68e-121 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
HIKJKDOL_01260 5.83e-118 yuaB - - - - - - -
HIKJKDOL_01261 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
HIKJKDOL_01262 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
HIKJKDOL_01263 3.31e-52 yubF - - S - - - yiaA/B two helix domain
HIKJKDOL_01264 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HIKJKDOL_01265 0.0 yubD - - P - - - Major Facilitator Superfamily
HIKJKDOL_01266 3.25e-112 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
HIKJKDOL_01268 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HIKJKDOL_01269 7.02e-252 yubA - - S - - - transporter activity
HIKJKDOL_01270 1.06e-234 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HIKJKDOL_01271 9.8e-317 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
HIKJKDOL_01272 8.22e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
HIKJKDOL_01273 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HIKJKDOL_01274 2.87e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HIKJKDOL_01275 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
HIKJKDOL_01277 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HIKJKDOL_01278 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HIKJKDOL_01279 2.29e-295 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HIKJKDOL_01280 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HIKJKDOL_01281 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HIKJKDOL_01282 2.04e-47 - - - - - - - -
HIKJKDOL_01283 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
HIKJKDOL_01284 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HIKJKDOL_01285 2.52e-300 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HIKJKDOL_01286 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
HIKJKDOL_01287 1.58e-50 - - - - - - - -
HIKJKDOL_01288 2.12e-70 mstX - - S - - - Membrane-integrating protein Mistic
HIKJKDOL_01289 3.56e-233 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
HIKJKDOL_01290 4.22e-95 yugN - - S - - - YugN-like family
HIKJKDOL_01292 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HIKJKDOL_01293 5.56e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
HIKJKDOL_01294 8.16e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
HIKJKDOL_01295 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
HIKJKDOL_01296 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
HIKJKDOL_01297 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
HIKJKDOL_01298 6.74e-112 alaR - - K - - - Transcriptional regulator
HIKJKDOL_01299 9.89e-201 yugF - - I - - - Hydrolase
HIKJKDOL_01300 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
HIKJKDOL_01301 3.19e-284 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HIKJKDOL_01302 1.76e-295 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HIKJKDOL_01303 6.12e-92 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
HIKJKDOL_01304 8.49e-150 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
HIKJKDOL_01306 8.9e-242 yuxJ - - EGP - - - Major facilitator superfamily
HIKJKDOL_01307 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
HIKJKDOL_01308 3.31e-98 yuxK - - S - - - protein conserved in bacteria
HIKJKDOL_01309 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
HIKJKDOL_01310 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HIKJKDOL_01311 1.14e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
HIKJKDOL_01312 1.28e-253 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
HIKJKDOL_01313 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HIKJKDOL_01314 9.08e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HIKJKDOL_01315 4.03e-214 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HIKJKDOL_01316 4.62e-308 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
HIKJKDOL_01317 1.42e-21 - - - - - - - -
HIKJKDOL_01318 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HIKJKDOL_01319 8.95e-90 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HIKJKDOL_01320 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HIKJKDOL_01321 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HIKJKDOL_01322 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HIKJKDOL_01323 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HIKJKDOL_01324 5.97e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
HIKJKDOL_01325 1.11e-82 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
HIKJKDOL_01326 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIKJKDOL_01327 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HIKJKDOL_01329 3.33e-168 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
HIKJKDOL_01330 6.29e-10 - - - S - - - DegQ (SacQ) family
HIKJKDOL_01332 8.73e-09 yuzC - - - - - - -
HIKJKDOL_01333 6.88e-297 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
HIKJKDOL_01334 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HIKJKDOL_01335 3.27e-134 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
HIKJKDOL_01336 2.19e-87 - - - S - - - Protein of unknown function (DUF1694)
HIKJKDOL_01337 1.34e-51 yueH - - S - - - YueH-like protein
HIKJKDOL_01338 1.23e-43 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
HIKJKDOL_01339 4.72e-245 yueF - - S - - - transporter activity
HIKJKDOL_01340 3.97e-93 - - - S - - - Protein of unknown function (DUF2283)
HIKJKDOL_01341 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
HIKJKDOL_01342 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
HIKJKDOL_01343 6.1e-171 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIKJKDOL_01344 4.37e-97 yueC - - S - - - Family of unknown function (DUF5383)
HIKJKDOL_01345 0.0 yueB - - S - - - type VII secretion protein EsaA
HIKJKDOL_01346 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HIKJKDOL_01347 8.62e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
HIKJKDOL_01348 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
HIKJKDOL_01349 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
HIKJKDOL_01350 1.03e-292 yukF - - QT - - - Transcriptional regulator
HIKJKDOL_01351 4.9e-263 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
HIKJKDOL_01352 2.07e-169 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
HIKJKDOL_01353 1.42e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
HIKJKDOL_01354 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIKJKDOL_01355 3.83e-229 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
HIKJKDOL_01356 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
HIKJKDOL_01357 2.99e-290 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
HIKJKDOL_01358 1.43e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HIKJKDOL_01359 1.55e-213 eSD - - S ko:K07017 - ko00000 Putative esterase
HIKJKDOL_01360 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
HIKJKDOL_01361 4.81e-124 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
HIKJKDOL_01362 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
HIKJKDOL_01363 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HIKJKDOL_01364 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
HIKJKDOL_01365 3.28e-151 yuiC - - S - - - protein conserved in bacteria
HIKJKDOL_01366 9.78e-47 yuiB - - S - - - Putative membrane protein
HIKJKDOL_01367 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HIKJKDOL_01368 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
HIKJKDOL_01370 4.51e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HIKJKDOL_01371 9.91e-150 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
HIKJKDOL_01372 5.66e-115 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIKJKDOL_01373 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
HIKJKDOL_01374 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HIKJKDOL_01375 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HIKJKDOL_01376 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
HIKJKDOL_01377 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HIKJKDOL_01378 6.61e-75 yuzD - - S - - - protein conserved in bacteria
HIKJKDOL_01379 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
HIKJKDOL_01380 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
HIKJKDOL_01381 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HIKJKDOL_01382 2.4e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HIKJKDOL_01383 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HIKJKDOL_01384 4.63e-255 yutH - - S - - - Spore coat protein
HIKJKDOL_01385 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
HIKJKDOL_01386 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HIKJKDOL_01387 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
HIKJKDOL_01388 3.2e-63 yutD - - S - - - protein conserved in bacteria
HIKJKDOL_01389 9.45e-145 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HIKJKDOL_01390 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HIKJKDOL_01391 2.66e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
HIKJKDOL_01392 4.25e-172 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
HIKJKDOL_01393 3.41e-65 yunC - - S - - - Domain of unknown function (DUF1805)
HIKJKDOL_01394 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HIKJKDOL_01395 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
HIKJKDOL_01396 3.5e-219 yunF - - S - - - Protein of unknown function DUF72
HIKJKDOL_01397 2.72e-82 yunG - - - - - - -
HIKJKDOL_01398 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HIKJKDOL_01399 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
HIKJKDOL_01400 1.46e-300 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
HIKJKDOL_01401 1.58e-283 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
HIKJKDOL_01402 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HIKJKDOL_01403 2.09e-72 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HIKJKDOL_01404 2.42e-122 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HIKJKDOL_01405 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HIKJKDOL_01406 4.85e-194 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HIKJKDOL_01407 2.62e-144 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
HIKJKDOL_01408 5.12e-243 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HIKJKDOL_01410 8.51e-306 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HIKJKDOL_01411 4.9e-303 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HIKJKDOL_01412 6.53e-218 bsn - - L - - - Ribonuclease
HIKJKDOL_01413 2.95e-263 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HIKJKDOL_01414 7.46e-176 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
HIKJKDOL_01415 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
HIKJKDOL_01416 1.94e-216 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HIKJKDOL_01417 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HIKJKDOL_01418 2.46e-308 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
HIKJKDOL_01419 2.24e-236 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HIKJKDOL_01420 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
HIKJKDOL_01421 1.42e-268 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
HIKJKDOL_01423 3.35e-56 - - - - - - - -
HIKJKDOL_01424 2.14e-87 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIKJKDOL_01425 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
HIKJKDOL_01426 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
HIKJKDOL_01427 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HIKJKDOL_01428 7.43e-313 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
HIKJKDOL_01429 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HIKJKDOL_01430 5.44e-81 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HIKJKDOL_01431 1.01e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
HIKJKDOL_01432 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
HIKJKDOL_01433 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HIKJKDOL_01434 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
HIKJKDOL_01435 2e-73 yusE - - CO - - - Thioredoxin
HIKJKDOL_01436 1.32e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
HIKJKDOL_01437 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
HIKJKDOL_01438 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HIKJKDOL_01439 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
HIKJKDOL_01440 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
HIKJKDOL_01441 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
HIKJKDOL_01442 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
HIKJKDOL_01443 1.11e-13 - - - S - - - YuzL-like protein
HIKJKDOL_01444 2.84e-210 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
HIKJKDOL_01445 2.23e-54 - - - - - - - -
HIKJKDOL_01446 8.66e-70 yusN - - M - - - Coat F domain
HIKJKDOL_01447 4.47e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
HIKJKDOL_01448 0.0 yusP - - P - - - Major facilitator superfamily
HIKJKDOL_01449 1.7e-84 yusQ - - S - - - Tautomerase enzyme
HIKJKDOL_01450 4.97e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HIKJKDOL_01451 8.42e-204 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
HIKJKDOL_01452 3.66e-64 yusU - - S - - - Protein of unknown function (DUF2573)
HIKJKDOL_01453 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HIKJKDOL_01454 3.48e-88 - - - S - - - YusW-like protein
HIKJKDOL_01455 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
HIKJKDOL_01456 6.65e-198 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HIKJKDOL_01457 1.07e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
HIKJKDOL_01458 9.63e-306 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HIKJKDOL_01459 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIKJKDOL_01460 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HIKJKDOL_01461 3.06e-204 yuxN - - K - - - Transcriptional regulator
HIKJKDOL_01462 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HIKJKDOL_01463 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
HIKJKDOL_01464 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HIKJKDOL_01465 2.9e-253 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
HIKJKDOL_01466 3.33e-247 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
HIKJKDOL_01467 1.56e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIKJKDOL_01468 9.56e-245 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HIKJKDOL_01469 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
HIKJKDOL_01470 3.11e-176 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
HIKJKDOL_01471 9.94e-143 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HIKJKDOL_01472 1.51e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
HIKJKDOL_01473 4.58e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HIKJKDOL_01474 2.35e-132 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
HIKJKDOL_01475 3.66e-309 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HIKJKDOL_01476 7.4e-234 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIKJKDOL_01477 8.18e-216 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HIKJKDOL_01478 8.63e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HIKJKDOL_01479 4.42e-218 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
HIKJKDOL_01480 0.0 yvrG - - T - - - Histidine kinase
HIKJKDOL_01481 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIKJKDOL_01482 5.07e-32 - - - - - - - -
HIKJKDOL_01483 5.77e-127 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
HIKJKDOL_01484 3.46e-26 - - - S - - - YvrJ protein family
HIKJKDOL_01485 9.23e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
HIKJKDOL_01486 2.84e-85 yvrL - - S - - - Regulatory protein YrvL
HIKJKDOL_01487 1.94e-271 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HIKJKDOL_01488 4.64e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HIKJKDOL_01489 1.15e-227 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
HIKJKDOL_01490 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HIKJKDOL_01491 3.92e-225 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIKJKDOL_01492 1.72e-236 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIKJKDOL_01493 1.81e-224 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HIKJKDOL_01495 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HIKJKDOL_01496 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
HIKJKDOL_01497 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
HIKJKDOL_01498 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
HIKJKDOL_01499 2.18e-215 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
HIKJKDOL_01500 3.49e-174 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
HIKJKDOL_01501 1.01e-152 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
HIKJKDOL_01502 3.07e-201 yvgN - - S - - - reductase
HIKJKDOL_01503 9.32e-112 yvgO - - - - - - -
HIKJKDOL_01504 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
HIKJKDOL_01505 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HIKJKDOL_01506 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HIKJKDOL_01507 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HIKJKDOL_01509 3.32e-139 yvgT - - S - - - membrane
HIKJKDOL_01510 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
HIKJKDOL_01511 3.45e-137 bdbD - - O - - - Thioredoxin
HIKJKDOL_01512 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
HIKJKDOL_01513 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HIKJKDOL_01514 3.66e-41 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
HIKJKDOL_01515 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
HIKJKDOL_01516 1.71e-248 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HIKJKDOL_01517 3.59e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HIKJKDOL_01518 0.0 - - - S - - - Fusaric acid resistance protein-like
HIKJKDOL_01519 8.22e-97 yvaD - - S - - - Family of unknown function (DUF5360)
HIKJKDOL_01520 3.52e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
HIKJKDOL_01521 8.9e-131 - - - K - - - Bacterial regulatory proteins, tetR family
HIKJKDOL_01522 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HIKJKDOL_01524 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HIKJKDOL_01525 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HIKJKDOL_01526 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
HIKJKDOL_01527 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
HIKJKDOL_01528 4.03e-196 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
HIKJKDOL_01529 3.44e-48 yvzC - - K - - - transcriptional
HIKJKDOL_01530 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
HIKJKDOL_01531 1.19e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HIKJKDOL_01532 3.85e-72 yvaP - - K - - - transcriptional
HIKJKDOL_01533 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HIKJKDOL_01534 2.26e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HIKJKDOL_01535 1.6e-218 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HIKJKDOL_01536 6.3e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HIKJKDOL_01537 2.86e-268 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HIKJKDOL_01538 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
HIKJKDOL_01539 5.59e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HIKJKDOL_01540 1.49e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HIKJKDOL_01541 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HIKJKDOL_01542 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HIKJKDOL_01543 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
HIKJKDOL_01544 2.66e-133 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
HIKJKDOL_01545 1.03e-145 yvbH - - S - - - YvbH-like oligomerisation region
HIKJKDOL_01546 5.38e-155 yvbI - - M - - - Membrane
HIKJKDOL_01547 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HIKJKDOL_01548 9.77e-106 yvbK - - K - - - acetyltransferase
HIKJKDOL_01549 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HIKJKDOL_01550 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
HIKJKDOL_01551 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HIKJKDOL_01552 1.62e-276 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HIKJKDOL_01553 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HIKJKDOL_01554 1.63e-235 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HIKJKDOL_01555 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HIKJKDOL_01556 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
HIKJKDOL_01557 2.98e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIKJKDOL_01558 4.9e-206 yvbU - - K - - - Transcriptional regulator
HIKJKDOL_01559 3.93e-198 yvbV - - EG - - - EamA-like transporter family
HIKJKDOL_01560 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HIKJKDOL_01561 3e-249 - - - S - - - Glycosyl hydrolase
HIKJKDOL_01562 1.45e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HIKJKDOL_01563 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HIKJKDOL_01564 9.08e-175 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HIKJKDOL_01565 4.36e-136 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIKJKDOL_01566 2.1e-249 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HIKJKDOL_01567 8.31e-170 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
HIKJKDOL_01568 7.43e-203 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
HIKJKDOL_01569 4.9e-199 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
HIKJKDOL_01570 2.3e-260 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
HIKJKDOL_01571 9.69e-317 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
HIKJKDOL_01572 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
HIKJKDOL_01573 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
HIKJKDOL_01574 1.3e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
HIKJKDOL_01575 2.05e-295 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
HIKJKDOL_01576 6.42e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HIKJKDOL_01577 1.18e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
HIKJKDOL_01578 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HIKJKDOL_01579 3.35e-304 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HIKJKDOL_01580 5.69e-44 yvfG - - S - - - YvfG protein
HIKJKDOL_01581 7.54e-241 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
HIKJKDOL_01582 1.91e-281 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
HIKJKDOL_01583 8.22e-77 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HIKJKDOL_01584 7.83e-140 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HIKJKDOL_01585 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HIKJKDOL_01586 2.36e-246 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HIKJKDOL_01587 4.13e-254 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
HIKJKDOL_01588 3.5e-248 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
HIKJKDOL_01589 2.95e-263 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
HIKJKDOL_01590 2.06e-277 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HIKJKDOL_01591 1.25e-201 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
HIKJKDOL_01592 6.66e-283 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
HIKJKDOL_01593 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
HIKJKDOL_01594 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
HIKJKDOL_01595 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
HIKJKDOL_01596 1.45e-97 - - - K ko:K19417 - ko00000,ko03000 transcriptional
HIKJKDOL_01597 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
HIKJKDOL_01599 8.97e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
HIKJKDOL_01600 7.42e-95 - - - S - - - Protein of unknown function (DUF3237)
HIKJKDOL_01601 8.37e-161 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HIKJKDOL_01602 0.0 pbpE - - V - - - Beta-lactamase
HIKJKDOL_01603 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
HIKJKDOL_01604 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HIKJKDOL_01605 0.0 ybeC - - E - - - amino acid
HIKJKDOL_01606 1.17e-137 yvdT_1 - - K - - - Transcriptional regulator
HIKJKDOL_01607 3.65e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HIKJKDOL_01608 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
HIKJKDOL_01609 5.53e-122 yvdQ - - S - - - Protein of unknown function (DUF3231)
HIKJKDOL_01610 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
HIKJKDOL_01611 2.71e-233 - - - S - - - Patatin-like phospholipase
HIKJKDOL_01613 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HIKJKDOL_01614 6.78e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HIKJKDOL_01615 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HIKJKDOL_01616 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
HIKJKDOL_01617 3.96e-197 malA - - S - - - Protein of unknown function (DUF1189)
HIKJKDOL_01618 6.84e-190 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
HIKJKDOL_01619 5e-310 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
HIKJKDOL_01620 2.42e-301 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
HIKJKDOL_01621 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
HIKJKDOL_01622 2.28e-223 yvdE - - K - - - Transcriptional regulator
HIKJKDOL_01623 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HIKJKDOL_01624 4.54e-70 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
HIKJKDOL_01625 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
HIKJKDOL_01626 3.73e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HIKJKDOL_01627 1.4e-235 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIKJKDOL_01628 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
HIKJKDOL_01629 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HIKJKDOL_01630 1.68e-252 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
HIKJKDOL_01631 4.67e-172 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIKJKDOL_01632 1.37e-45 - - - - - - - -
HIKJKDOL_01633 5.24e-188 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
HIKJKDOL_01634 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
HIKJKDOL_01635 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HIKJKDOL_01636 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HIKJKDOL_01637 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HIKJKDOL_01638 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HIKJKDOL_01639 1.18e-225 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HIKJKDOL_01640 1.08e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
HIKJKDOL_01641 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
HIKJKDOL_01642 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HIKJKDOL_01644 0.0 - - - - - - - -
HIKJKDOL_01645 6.58e-95 - - - - - - - -
HIKJKDOL_01646 8.75e-91 - - - - - - - -
HIKJKDOL_01647 2.51e-144 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
HIKJKDOL_01648 2.79e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HIKJKDOL_01649 1.96e-168 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HIKJKDOL_01650 2.82e-147 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HIKJKDOL_01651 2.87e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
HIKJKDOL_01652 1.05e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HIKJKDOL_01653 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HIKJKDOL_01654 6.64e-279 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HIKJKDOL_01655 2.49e-178 yvpB - - NU - - - protein conserved in bacteria
HIKJKDOL_01656 1.1e-153 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
HIKJKDOL_01657 1.69e-108 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HIKJKDOL_01658 1.76e-152 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HIKJKDOL_01659 3.05e-210 yvoD - - P - - - COG0370 Fe2 transport system protein B
HIKJKDOL_01660 1.06e-193 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HIKJKDOL_01661 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HIKJKDOL_01662 9.39e-277 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HIKJKDOL_01663 8.26e-164 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HIKJKDOL_01664 1.5e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
HIKJKDOL_01665 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
HIKJKDOL_01666 9.4e-110 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
HIKJKDOL_01667 1.61e-293 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HIKJKDOL_01668 2.49e-177 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HIKJKDOL_01669 6.2e-114 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
HIKJKDOL_01670 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
HIKJKDOL_01671 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
HIKJKDOL_01672 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
HIKJKDOL_01673 5.8e-221 yvlB - - S - - - Putative adhesin
HIKJKDOL_01674 8.09e-65 yvlA - - - - - - -
HIKJKDOL_01675 2.73e-46 yvkN - - - - - - -
HIKJKDOL_01676 2.57e-104 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HIKJKDOL_01677 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HIKJKDOL_01678 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HIKJKDOL_01679 2.54e-42 csbA - - S - - - protein conserved in bacteria
HIKJKDOL_01680 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
HIKJKDOL_01681 1.43e-131 yvkB - - K - - - Transcriptional regulator
HIKJKDOL_01682 5.47e-298 yvkA - - P - - - -transporter
HIKJKDOL_01683 3.86e-281 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HIKJKDOL_01684 1.38e-73 swrA - - S - - - Swarming motility protein
HIKJKDOL_01685 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HIKJKDOL_01686 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HIKJKDOL_01687 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
HIKJKDOL_01688 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
HIKJKDOL_01689 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HIKJKDOL_01690 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HIKJKDOL_01691 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HIKJKDOL_01692 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HIKJKDOL_01693 1.25e-85 - - - - - - - -
HIKJKDOL_01694 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
HIKJKDOL_01695 5.15e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
HIKJKDOL_01696 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HIKJKDOL_01697 1.1e-76 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
HIKJKDOL_01698 8.01e-202 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HIKJKDOL_01699 2.58e-41 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HIKJKDOL_01700 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HIKJKDOL_01701 4.19e-93 yviE - - - - - - -
HIKJKDOL_01702 1.97e-199 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
HIKJKDOL_01703 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
HIKJKDOL_01704 3.5e-102 yvyG - - NOU - - - FlgN protein
HIKJKDOL_01705 1.06e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
HIKJKDOL_01706 1.83e-96 yvyF - - S - - - flagellar protein
HIKJKDOL_01707 9.99e-166 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
HIKJKDOL_01708 1.26e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
HIKJKDOL_01709 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HIKJKDOL_01710 2.15e-199 degV - - S - - - protein conserved in bacteria
HIKJKDOL_01711 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIKJKDOL_01712 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HIKJKDOL_01713 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
HIKJKDOL_01714 3.99e-225 yvhJ - - K - - - Transcriptional regulator
HIKJKDOL_01715 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HIKJKDOL_01716 3.3e-303 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
HIKJKDOL_01717 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
HIKJKDOL_01718 6.04e-149 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
HIKJKDOL_01719 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
HIKJKDOL_01720 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HIKJKDOL_01721 5.68e-279 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
HIKJKDOL_01722 2.81e-313 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HIKJKDOL_01723 3.01e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HIKJKDOL_01724 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HIKJKDOL_01725 0.0 lytB - - D - - - Stage II sporulation protein
HIKJKDOL_01726 3.26e-50 - - - - - - - -
HIKJKDOL_01727 2.77e-219 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HIKJKDOL_01728 6.61e-278 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HIKJKDOL_01729 1.78e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HIKJKDOL_01730 3.21e-71 - - - - - - - -
HIKJKDOL_01731 3.03e-248 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HIKJKDOL_01732 1.82e-113 - - - M - - - Glycosyltransferase like family 2
HIKJKDOL_01733 1.86e-47 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HIKJKDOL_01734 5.59e-68 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HIKJKDOL_01735 1.52e-46 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HIKJKDOL_01736 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HIKJKDOL_01737 1.19e-193 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
HIKJKDOL_01738 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HIKJKDOL_01739 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
HIKJKDOL_01740 3.82e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
HIKJKDOL_01741 1.9e-185 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HIKJKDOL_01742 3.8e-273 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HIKJKDOL_01743 0.0 - - - - - - - -
HIKJKDOL_01744 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HIKJKDOL_01745 1.07e-237 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HIKJKDOL_01746 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HIKJKDOL_01747 1.73e-247 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
HIKJKDOL_01748 2.52e-263 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
HIKJKDOL_01749 8.19e-316 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HIKJKDOL_01750 1.48e-222 ywtF_2 - - K - - - Transcriptional regulator
HIKJKDOL_01751 7.24e-205 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HIKJKDOL_01752 1.37e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HIKJKDOL_01753 2.29e-29 ywtC - - - - - - -
HIKJKDOL_01754 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HIKJKDOL_01755 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
HIKJKDOL_01756 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
HIKJKDOL_01757 2.68e-227 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
HIKJKDOL_01758 6.44e-207 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HIKJKDOL_01759 5.6e-85 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HIKJKDOL_01760 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HIKJKDOL_01761 5.54e-202 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HIKJKDOL_01762 1.28e-203 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
HIKJKDOL_01763 4.83e-120 batE - - T - - - Sh3 type 3 domain protein
HIKJKDOL_01764 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
HIKJKDOL_01765 2.15e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
HIKJKDOL_01766 5.26e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
HIKJKDOL_01767 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HIKJKDOL_01768 3.36e-218 alsR - - K - - - LysR substrate binding domain
HIKJKDOL_01769 2.79e-280 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HIKJKDOL_01770 3.04e-162 ywrJ - - - - - - -
HIKJKDOL_01771 2.39e-176 cotB - - - ko:K06325 - ko00000 -
HIKJKDOL_01772 4.57e-269 cotH - - M ko:K06330 - ko00000 Spore Coat
HIKJKDOL_01773 2.17e-16 - - - - - - - -
HIKJKDOL_01774 4.35e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HIKJKDOL_01775 1.13e-70 - - - S - - - Domain of unknown function (DUF4181)
HIKJKDOL_01776 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
HIKJKDOL_01777 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
HIKJKDOL_01778 4.53e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
HIKJKDOL_01779 6.07e-114 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
HIKJKDOL_01781 5.23e-130 ywqN - - S - - - NAD(P)H-dependent
HIKJKDOL_01782 4.73e-209 - - - K - - - Transcriptional regulator
HIKJKDOL_01783 9.14e-152 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HIKJKDOL_01785 2.32e-99 ywqJ - - S - - - Pre-toxin TG
HIKJKDOL_01786 1.3e-23 - - - - - - - -
HIKJKDOL_01787 1.77e-26 - - - - - - - -
HIKJKDOL_01788 5.16e-264 - - - L - - - nucleic acid phosphodiester bond hydrolysis
HIKJKDOL_01789 5.12e-51 ywqI - - S - - - Family of unknown function (DUF5344)
HIKJKDOL_01791 5.95e-196 ywqG - - S - - - Domain of unknown function (DUF1963)
HIKJKDOL_01792 2.21e-311 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HIKJKDOL_01793 1.44e-179 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
HIKJKDOL_01794 1.76e-153 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
HIKJKDOL_01795 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
HIKJKDOL_01796 3.6e-25 - - - - - - - -
HIKJKDOL_01797 0.0 ywqB - - S - - - SWIM zinc finger
HIKJKDOL_01798 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
HIKJKDOL_01799 2.06e-199 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HIKJKDOL_01800 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HIKJKDOL_01801 8.53e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
HIKJKDOL_01802 3.04e-87 ywpG - - - - - - -
HIKJKDOL_01803 8.81e-89 ywpF - - S - - - YwpF-like protein
HIKJKDOL_01804 1.09e-66 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HIKJKDOL_01805 7.02e-197 ywpD - - T - - - Histidine kinase
HIKJKDOL_01806 1.61e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HIKJKDOL_01807 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HIKJKDOL_01808 9.03e-256 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
HIKJKDOL_01809 5.58e-180 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
HIKJKDOL_01810 4.16e-171 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
HIKJKDOL_01811 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
HIKJKDOL_01812 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
HIKJKDOL_01813 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
HIKJKDOL_01814 3.21e-268 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HIKJKDOL_01815 1.69e-311 ywoF - - P - - - Right handed beta helix region
HIKJKDOL_01816 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
HIKJKDOL_01817 3.25e-308 ywoD - - EGP - - - Major facilitator superfamily
HIKJKDOL_01818 2.56e-134 yjgF - - Q - - - Isochorismatase family
HIKJKDOL_01819 4.15e-100 - - - - - - - -
HIKJKDOL_01820 1.6e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
HIKJKDOL_01821 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
HIKJKDOL_01822 6.02e-135 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
HIKJKDOL_01823 2.7e-94 ywnJ - - S - - - VanZ like family
HIKJKDOL_01824 3.91e-163 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
HIKJKDOL_01825 5.19e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
HIKJKDOL_01826 1.85e-21 ywnC - - S - - - Family of unknown function (DUF5362)
HIKJKDOL_01827 7.07e-92 ywnF - - S - - - Family of unknown function (DUF5392)
HIKJKDOL_01828 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIKJKDOL_01829 2.69e-181 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
HIKJKDOL_01830 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
HIKJKDOL_01831 1.29e-148 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
HIKJKDOL_01832 4.58e-85 ywnA - - K - - - Transcriptional regulator
HIKJKDOL_01833 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HIKJKDOL_01834 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
HIKJKDOL_01835 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
HIKJKDOL_01837 1.11e-21 csbD - - K - - - CsbD-like
HIKJKDOL_01838 1.12e-109 ywmF - - S - - - Peptidase M50
HIKJKDOL_01839 1.25e-128 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HIKJKDOL_01840 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HIKJKDOL_01841 2.22e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HIKJKDOL_01843 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HIKJKDOL_01844 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HIKJKDOL_01845 2.8e-233 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
HIKJKDOL_01846 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HIKJKDOL_01847 2.39e-174 ywmB - - S - - - TATA-box binding
HIKJKDOL_01848 4.54e-45 ywzB - - S - - - membrane
HIKJKDOL_01849 6.46e-80 ywmA - - - - - - -
HIKJKDOL_01851 1.04e-76 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HIKJKDOL_01852 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HIKJKDOL_01853 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HIKJKDOL_01854 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HIKJKDOL_01855 9.66e-117 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIKJKDOL_01856 1.24e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HIKJKDOL_01857 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIKJKDOL_01858 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HIKJKDOL_01859 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
HIKJKDOL_01860 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HIKJKDOL_01861 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HIKJKDOL_01862 2.9e-122 ywlG - - S - - - Belongs to the UPF0340 family
HIKJKDOL_01863 1.36e-105 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
HIKJKDOL_01864 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIKJKDOL_01865 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
HIKJKDOL_01866 1.22e-249 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HIKJKDOL_01867 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
HIKJKDOL_01868 1.14e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
HIKJKDOL_01869 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HIKJKDOL_01871 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HIKJKDOL_01872 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HIKJKDOL_01873 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIKJKDOL_01874 6.26e-119 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HIKJKDOL_01875 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
HIKJKDOL_01876 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
HIKJKDOL_01877 4.06e-134 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HIKJKDOL_01878 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
HIKJKDOL_01879 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HIKJKDOL_01880 3.51e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
HIKJKDOL_01881 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HIKJKDOL_01882 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HIKJKDOL_01883 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
HIKJKDOL_01884 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
HIKJKDOL_01885 2.61e-117 ywjG - - S - - - Domain of unknown function (DUF2529)
HIKJKDOL_01886 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HIKJKDOL_01887 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HIKJKDOL_01888 3.48e-268 acdA - - I - - - acyl-CoA dehydrogenase
HIKJKDOL_01889 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
HIKJKDOL_01890 2.86e-288 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HIKJKDOL_01891 4.01e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HIKJKDOL_01892 1.32e-57 ywjC - - - - - - -
HIKJKDOL_01893 1.35e-124 ywjB - - H - - - RibD C-terminal domain
HIKJKDOL_01894 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
HIKJKDOL_01895 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIKJKDOL_01896 2.06e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
HIKJKDOL_01897 7.94e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
HIKJKDOL_01898 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
HIKJKDOL_01899 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HIKJKDOL_01900 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
HIKJKDOL_01901 1.84e-179 ywiC - - S - - - YwiC-like protein
HIKJKDOL_01902 2.69e-167 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
HIKJKDOL_01903 3.44e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
HIKJKDOL_01904 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HIKJKDOL_01905 4.64e-96 ywiB - - S - - - protein conserved in bacteria
HIKJKDOL_01906 3.71e-12 - - - S - - - Bacteriocin subtilosin A
HIKJKDOL_01907 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
HIKJKDOL_01909 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HIKJKDOL_01910 1.7e-297 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
HIKJKDOL_01911 2.94e-277 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
HIKJKDOL_01912 0.0 - - - L - - - Peptidase, M16
HIKJKDOL_01914 8.17e-316 ywhL - - CO - - - amine dehydrogenase activity
HIKJKDOL_01915 1.34e-274 ywhK - - CO - - - amine dehydrogenase activity
HIKJKDOL_01916 3.28e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HIKJKDOL_01918 2.17e-37 - - - S - - - Aminoacyl-tRNA editing domain
HIKJKDOL_01919 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
HIKJKDOL_01920 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HIKJKDOL_01921 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HIKJKDOL_01922 2.1e-64 - - - - - - - -
HIKJKDOL_01923 1.92e-123 ywhD - - S - - - YwhD family
HIKJKDOL_01924 3.29e-154 ywhC - - S - - - Peptidase family M50
HIKJKDOL_01925 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
HIKJKDOL_01926 1.45e-93 ywhA - - K - - - Transcriptional regulator
HIKJKDOL_01927 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HIKJKDOL_01929 8.75e-300 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
HIKJKDOL_01930 3.15e-103 yffB - - K - - - Transcriptional regulator
HIKJKDOL_01931 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
HIKJKDOL_01932 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
HIKJKDOL_01933 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
HIKJKDOL_01934 5.65e-147 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
HIKJKDOL_01935 1.51e-202 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
HIKJKDOL_01936 3.05e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HIKJKDOL_01937 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
HIKJKDOL_01938 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
HIKJKDOL_01939 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
HIKJKDOL_01940 2.77e-175 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
HIKJKDOL_01941 9e-297 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
HIKJKDOL_01942 3.21e-267 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
HIKJKDOL_01943 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HIKJKDOL_01944 6.34e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIKJKDOL_01945 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HIKJKDOL_01946 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HIKJKDOL_01947 7.68e-275 ywfA - - EGP - - - -transporter
HIKJKDOL_01948 1.5e-315 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HIKJKDOL_01949 0.0 rocB - - E - - - arginine degradation protein
HIKJKDOL_01950 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
HIKJKDOL_01951 2.46e-309 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HIKJKDOL_01952 3.7e-101 - - - - - - - -
HIKJKDOL_01953 3.73e-113 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
HIKJKDOL_01954 4.72e-204 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HIKJKDOL_01955 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HIKJKDOL_01956 7.45e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HIKJKDOL_01957 2.5e-234 spsG - - M - - - Spore Coat
HIKJKDOL_01958 1.05e-165 spsF - - M ko:K07257 - ko00000 Spore Coat
HIKJKDOL_01959 6.52e-270 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
HIKJKDOL_01960 1.41e-208 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
HIKJKDOL_01961 8.77e-283 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
HIKJKDOL_01962 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
HIKJKDOL_01963 3.84e-185 spsA - - M - - - Spore Coat
HIKJKDOL_01964 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HIKJKDOL_01965 1.59e-78 ywdK - - S - - - small membrane protein
HIKJKDOL_01966 1.86e-303 ywdJ - - F - - - Xanthine uracil
HIKJKDOL_01967 4.4e-63 ywdI - - S - - - Family of unknown function (DUF5327)
HIKJKDOL_01968 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HIKJKDOL_01969 9.47e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HIKJKDOL_01970 9.44e-192 ywdF - - S - - - Glycosyltransferase like family 2
HIKJKDOL_01971 2.21e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HIKJKDOL_01972 6.19e-39 ywdA - - - - - - -
HIKJKDOL_01973 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HIKJKDOL_01974 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HIKJKDOL_01975 3.4e-179 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
HIKJKDOL_01976 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HIKJKDOL_01978 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HIKJKDOL_01979 3.44e-238 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIKJKDOL_01980 9.4e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
HIKJKDOL_01981 1.26e-268 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HIKJKDOL_01982 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
HIKJKDOL_01983 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
HIKJKDOL_01984 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
HIKJKDOL_01985 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HIKJKDOL_01986 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HIKJKDOL_01987 5.11e-49 ydaS - - S - - - membrane
HIKJKDOL_01988 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HIKJKDOL_01989 2.96e-286 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HIKJKDOL_01990 3.33e-77 gtcA - - S - - - GtrA-like protein
HIKJKDOL_01991 3.42e-158 ywcC - - K - - - transcriptional regulator
HIKJKDOL_01993 7.41e-65 ywcB - - S - - - Protein of unknown function, DUF485
HIKJKDOL_01994 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIKJKDOL_01995 1.54e-142 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
HIKJKDOL_01996 2.54e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
HIKJKDOL_01997 2.81e-245 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
HIKJKDOL_01998 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
HIKJKDOL_01999 1.81e-148 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HIKJKDOL_02000 3.79e-184 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HIKJKDOL_02001 2.7e-203 ywbI - - K - - - Transcriptional regulator
HIKJKDOL_02002 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HIKJKDOL_02003 1.21e-143 ywbG - - M - - - effector of murein hydrolase
HIKJKDOL_02004 2.91e-275 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
HIKJKDOL_02005 3.13e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
HIKJKDOL_02006 3.29e-279 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
HIKJKDOL_02007 4.01e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
HIKJKDOL_02008 5.44e-122 - - - N - - - domain, Protein
HIKJKDOL_02009 2.5e-161 ywbB - - S - - - Protein of unknown function (DUF2711)
HIKJKDOL_02010 2.03e-308 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIKJKDOL_02011 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HIKJKDOL_02012 2.79e-310 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HIKJKDOL_02013 3.03e-194 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HIKJKDOL_02014 5.37e-216 gspA - - M - - - General stress
HIKJKDOL_02015 2.11e-159 ywaF - - S - - - Integral membrane protein
HIKJKDOL_02016 7.22e-114 ywaE - - K - - - Transcriptional regulator
HIKJKDOL_02017 2.9e-293 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HIKJKDOL_02018 9.14e-317 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
HIKJKDOL_02019 1.53e-115 - - - K - - - Helix-turn-helix XRE-family like proteins
HIKJKDOL_02020 7.93e-64 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
HIKJKDOL_02021 1.6e-164 - - - EGP - - - Permeases of the major facilitator superfamily
HIKJKDOL_02022 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
HIKJKDOL_02023 4.89e-211 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
HIKJKDOL_02024 1.27e-20 - - - S - - - D-Ala-teichoic acid biosynthesis protein
HIKJKDOL_02025 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIKJKDOL_02026 3.26e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
HIKJKDOL_02027 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIKJKDOL_02028 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HIKJKDOL_02029 5.63e-176 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HIKJKDOL_02030 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HIKJKDOL_02031 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HIKJKDOL_02032 8.33e-68 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HIKJKDOL_02033 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIKJKDOL_02034 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
HIKJKDOL_02035 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
HIKJKDOL_02036 8.94e-28 yxzF - - - - - - -
HIKJKDOL_02037 1.32e-144 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HIKJKDOL_02038 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HIKJKDOL_02039 1.87e-269 yxlH - - EGP - - - Major Facilitator Superfamily
HIKJKDOL_02040 3.8e-177 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HIKJKDOL_02041 2.35e-210 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HIKJKDOL_02042 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
HIKJKDOL_02043 2.92e-42 - - - - - - - -
HIKJKDOL_02044 5.53e-62 yxlC - - S - - - Family of unknown function (DUF5345)
HIKJKDOL_02045 1.29e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HIKJKDOL_02046 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
HIKJKDOL_02047 1.77e-200 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HIKJKDOL_02048 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
HIKJKDOL_02049 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
HIKJKDOL_02050 4.74e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
HIKJKDOL_02051 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
HIKJKDOL_02052 3.97e-310 cimH - - C - - - COG3493 Na citrate symporter
HIKJKDOL_02053 0.0 - - - O - - - Peptidase family M48
HIKJKDOL_02055 2.81e-194 yxkH - - G - - - Polysaccharide deacetylase
HIKJKDOL_02056 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HIKJKDOL_02057 1.12e-209 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
HIKJKDOL_02058 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HIKJKDOL_02059 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIKJKDOL_02060 1.95e-99 yxkC - - S - - - Domain of unknown function (DUF4352)
HIKJKDOL_02061 2.11e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HIKJKDOL_02062 3.81e-100 - - - S - - - Protein of unknown function (DUF1453)
HIKJKDOL_02063 3.23e-257 - - - T - - - Signal transduction histidine kinase
HIKJKDOL_02064 2.69e-148 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
HIKJKDOL_02065 1.83e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HIKJKDOL_02067 1.74e-112 yxjI - - S - - - LURP-one-related
HIKJKDOL_02068 7.74e-280 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HIKJKDOL_02069 9.77e-279 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HIKJKDOL_02070 5.83e-176 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HIKJKDOL_02071 6.9e-150 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HIKJKDOL_02072 4.65e-168 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HIKJKDOL_02073 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
HIKJKDOL_02074 4.19e-202 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
HIKJKDOL_02075 1.21e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HIKJKDOL_02076 9.87e-132 - - - T - - - Domain of unknown function (DUF4163)
HIKJKDOL_02077 2.28e-63 yxiS - - - - - - -
HIKJKDOL_02078 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HIKJKDOL_02079 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HIKJKDOL_02080 7.21e-183 bglS - - M - - - licheninase activity
HIKJKDOL_02081 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HIKJKDOL_02082 5.09e-141 - - - - - - - -
HIKJKDOL_02083 6.57e-293 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
HIKJKDOL_02084 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HIKJKDOL_02085 3.28e-279 - - - E - - - GDSL-like Lipase/Acylhydrolase
HIKJKDOL_02088 5.53e-65 yxiJ - - S - - - YxiJ-like protein
HIKJKDOL_02089 3.79e-125 yxiI - - S - - - Protein of unknown function (DUF2716)
HIKJKDOL_02090 6.22e-107 - - - - - - - -
HIKJKDOL_02091 1.2e-57 - - - - - - - -
HIKJKDOL_02092 8.76e-99 yxiG - - - - - - -
HIKJKDOL_02093 1.12e-82 - - - - - - - -
HIKJKDOL_02094 3.69e-111 - - - - - - - -
HIKJKDOL_02095 1.09e-94 yxxG - - - - - - -
HIKJKDOL_02096 0.0 wapA - - M - - - COG3209 Rhs family protein
HIKJKDOL_02097 1.17e-216 yxxF - - EG - - - EamA-like transporter family
HIKJKDOL_02098 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
HIKJKDOL_02099 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HIKJKDOL_02100 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HIKJKDOL_02101 1.33e-67 - - - - - - - -
HIKJKDOL_02102 9.25e-103 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
HIKJKDOL_02103 0.0 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
HIKJKDOL_02104 2.3e-53 yxiC - - S - - - Family of unknown function (DUF5344)
HIKJKDOL_02105 1.88e-37 - - - S - - - Domain of unknown function (DUF5082)
HIKJKDOL_02106 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
HIKJKDOL_02107 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HIKJKDOL_02108 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
HIKJKDOL_02109 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HIKJKDOL_02110 2.44e-303 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
HIKJKDOL_02111 4.85e-231 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HIKJKDOL_02112 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HIKJKDOL_02113 4.9e-300 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
HIKJKDOL_02114 1.57e-262 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HIKJKDOL_02115 8.3e-150 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HIKJKDOL_02116 4.26e-222 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HIKJKDOL_02117 3.56e-195 - - - S - - - Domain of Unknown Function (DUF1206)
HIKJKDOL_02118 4.86e-259 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
HIKJKDOL_02119 0.0 yxeQ - - S - - - MmgE/PrpD family
HIKJKDOL_02120 5.21e-275 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
HIKJKDOL_02121 1.67e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HIKJKDOL_02122 1.81e-149 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HIKJKDOL_02123 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HIKJKDOL_02124 2.46e-118 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIKJKDOL_02125 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIKJKDOL_02127 2.17e-243 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
HIKJKDOL_02128 8.09e-194 yxeH - - S - - - hydrolases of the HAD superfamily
HIKJKDOL_02131 7.32e-42 yxeE - - - - - - -
HIKJKDOL_02132 2.66e-28 yxeD - - - - - - -
HIKJKDOL_02133 6.79e-91 - - - - - - - -
HIKJKDOL_02134 1.05e-226 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HIKJKDOL_02135 2.43e-76 yxeA - - S - - - Protein of unknown function (DUF1093)
HIKJKDOL_02136 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
HIKJKDOL_02137 9.39e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HIKJKDOL_02138 7.73e-231 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HIKJKDOL_02139 1.62e-159 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIKJKDOL_02140 6.95e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HIKJKDOL_02141 3.63e-185 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HIKJKDOL_02142 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
HIKJKDOL_02143 1.55e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HIKJKDOL_02144 4.19e-298 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
HIKJKDOL_02145 4.27e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HIKJKDOL_02146 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HIKJKDOL_02147 1.23e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HIKJKDOL_02148 2.43e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HIKJKDOL_02149 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HIKJKDOL_02150 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HIKJKDOL_02151 3.52e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
HIKJKDOL_02153 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
HIKJKDOL_02154 1.77e-314 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HIKJKDOL_02155 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
HIKJKDOL_02157 4.33e-195 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HIKJKDOL_02158 3.66e-275 yxbF - - K - - - Bacterial regulatory proteins, tetR family
HIKJKDOL_02159 1.21e-315 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HIKJKDOL_02160 6.59e-111 yxbD 3.2.2.20 - K ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Acetyltransferase (GNAT) domain
HIKJKDOL_02161 1.16e-239 - - - S - - - A domain family that is part of the cupin metalloenzyme superfamily.
HIKJKDOL_02162 1.29e-177 yxbB - - Q - - - Met-10+ like-protein
HIKJKDOL_02163 3.65e-59 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
HIKJKDOL_02164 8.99e-114 yxnB - - - - - - -
HIKJKDOL_02165 0.0 - 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HIKJKDOL_02166 1.8e-271 yxaM - - U - - - MFS_1 like family
HIKJKDOL_02167 2.63e-137 yxaL - - S - - - PQQ-like domain
HIKJKDOL_02168 1.43e-85 - - - S - - - Family of unknown function (DUF5391)
HIKJKDOL_02169 2.83e-99 yxaI - - S - - - membrane protein domain
HIKJKDOL_02170 2.88e-290 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
HIKJKDOL_02171 1.55e-252 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
HIKJKDOL_02172 2.75e-130 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
HIKJKDOL_02173 5.23e-256 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HIKJKDOL_02174 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HIKJKDOL_02175 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
HIKJKDOL_02176 1.27e-152 yxaC - - M - - - effector of murein hydrolase
HIKJKDOL_02177 3.62e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
HIKJKDOL_02178 4.04e-264 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HIKJKDOL_02179 3.63e-163 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
HIKJKDOL_02180 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HIKJKDOL_02181 5.87e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HIKJKDOL_02182 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HIKJKDOL_02183 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
HIKJKDOL_02184 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
HIKJKDOL_02185 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HIKJKDOL_02186 1.15e-37 - 2.7.1.199 - G ko:K02777,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
HIKJKDOL_02187 1.95e-159 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
HIKJKDOL_02188 9.5e-153 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HIKJKDOL_02189 8.4e-143 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HIKJKDOL_02190 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
HIKJKDOL_02191 5.33e-258 - - - S - - - SIR2-like domain
HIKJKDOL_02192 1.46e-223 - - - L - - - DNA synthesis involved in DNA repair
HIKJKDOL_02193 1.23e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HIKJKDOL_02195 3.31e-89 - - - - - - - -
HIKJKDOL_02196 2.58e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HIKJKDOL_02198 1.58e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
HIKJKDOL_02199 3.79e-255 yycP - - - - - - -
HIKJKDOL_02200 7.97e-168 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HIKJKDOL_02201 3.04e-110 yycN - - K - - - Acetyltransferase
HIKJKDOL_02202 8.7e-239 - - - S - - - aspartate phosphatase
HIKJKDOL_02204 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
HIKJKDOL_02205 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HIKJKDOL_02206 1.01e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
HIKJKDOL_02207 5.82e-20 - - - - - - - -
HIKJKDOL_02208 4.85e-119 - - - - - - - -
HIKJKDOL_02209 6.81e-19 - - - S - - - Sporulation delaying protein SdpA
HIKJKDOL_02210 3.95e-87 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HIKJKDOL_02211 2.31e-54 sdpR - - K - - - transcriptional
HIKJKDOL_02212 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HIKJKDOL_02213 9.16e-215 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HIKJKDOL_02214 6.75e-122 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
HIKJKDOL_02215 1.88e-97 - - - S - - - Peptidase propeptide and YPEB domain
HIKJKDOL_02216 1.4e-43 - - - S - - - Peptidase propeptide and YPEB domain
HIKJKDOL_02217 4.48e-277 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HIKJKDOL_02218 3.29e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HIKJKDOL_02219 1.2e-200 yycI - - S - - - protein conserved in bacteria
HIKJKDOL_02220 0.0 yycH - - S - - - protein conserved in bacteria
HIKJKDOL_02221 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HIKJKDOL_02222 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIKJKDOL_02227 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HIKJKDOL_02228 4.68e-99 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIKJKDOL_02229 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HIKJKDOL_02230 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HIKJKDOL_02232 1.89e-22 yycC - - K - - - YycC-like protein
HIKJKDOL_02233 4.19e-283 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
HIKJKDOL_02234 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HIKJKDOL_02235 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HIKJKDOL_02236 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HIKJKDOL_02237 1.5e-204 yybS - - S - - - membrane
HIKJKDOL_02239 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
HIKJKDOL_02240 1.3e-87 yybR - - K - - - Transcriptional regulator
HIKJKDOL_02241 2.83e-209 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
HIKJKDOL_02242 3.19e-90 - - - - - - - -
HIKJKDOL_02244 2.03e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HIKJKDOL_02245 4.38e-142 - - - K - - - TipAS antibiotic-recognition domain
HIKJKDOL_02246 2.05e-183 - - - - - - - -
HIKJKDOL_02247 2.49e-87 - - - S - - - SnoaL-like domain
HIKJKDOL_02248 1.51e-73 yybG - - S - - - Pentapeptide repeat-containing protein
HIKJKDOL_02249 3.03e-277 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HIKJKDOL_02250 4.56e-211 yybE - - K - - - Transcriptional regulator
HIKJKDOL_02251 1.08e-101 yjcF - - S - - - Acetyltransferase (GNAT) domain
HIKJKDOL_02252 3.91e-94 yybC - - - - - - -
HIKJKDOL_02253 4.88e-161 - - - S - - - Metallo-beta-lactamase superfamily
HIKJKDOL_02254 4.54e-100 yybA - - K - - - transcriptional
HIKJKDOL_02255 2.44e-94 yjcF - - S - - - Acetyltransferase (GNAT) domain
HIKJKDOL_02256 1.74e-124 yyaS - - S ko:K07149 - ko00000 Membrane
HIKJKDOL_02257 1.84e-117 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
HIKJKDOL_02258 1.5e-85 - - - S - - - YjbR
HIKJKDOL_02259 8.62e-137 yyaP - - H - - - RibD C-terminal domain
HIKJKDOL_02260 4.67e-313 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
HIKJKDOL_02261 1.46e-58 yyaL - - O ko:K06888 - ko00000 Highly conserved protein containing a thioredoxin domain
HIKJKDOL_02262 5.45e-88 - - - K - - - MerR HTH family regulatory protein
HIKJKDOL_02263 5.69e-207 - - - EG - - - EamA-like transporter family
HIKJKDOL_02264 1.24e-36 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
HIKJKDOL_02265 1.82e-24 - - - L - - - resolvase
HIKJKDOL_02267 1.29e-83 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
HIKJKDOL_02268 3.19e-111 yddI - - - - - - -
HIKJKDOL_02269 7.54e-240 yddH - - M - - - Lysozyme-like
HIKJKDOL_02270 0.0 yddG - - S - - - maturation of SSU-rRNA
HIKJKDOL_02271 1.1e-71 - - - S - - - Domain of unknown function (DUF1874)
HIKJKDOL_02272 0.0 yddE - - S - - - AAA-like domain
HIKJKDOL_02273 2.93e-119 yddD - - S - - - TcpE family
HIKJKDOL_02274 6.88e-54 yddC - - - - - - -
HIKJKDOL_02275 1.84e-223 yddB - - S - - - Conjugative transposon protein TcpC
HIKJKDOL_02277 1.85e-58 yddA - - - - - - -
HIKJKDOL_02282 1.19e-234 nicK - - L ko:K07467 - ko00000 Replication initiation factor
HIKJKDOL_02283 0.0 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
HIKJKDOL_02284 1.84e-83 - - - S - - - Bacterial protein of unknown function (DUF961)
HIKJKDOL_02286 3.32e-20 - - - - - - - -
HIKJKDOL_02287 3.16e-55 - - - K - - - Transcriptional
HIKJKDOL_02288 3.11e-58 - - - E - - - IrrE N-terminal-like domain
HIKJKDOL_02289 7.38e-93 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HIKJKDOL_02291 1.76e-26 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
HIKJKDOL_02292 1.3e-128 - - - S - - - Type II restriction endonuclease EcoO109I
HIKJKDOL_02293 1.12e-275 dcm 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
HIKJKDOL_02294 8.21e-29 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
HIKJKDOL_02295 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
HIKJKDOL_02296 4.94e-214 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
HIKJKDOL_02297 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
HIKJKDOL_02298 1.55e-128 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
HIKJKDOL_02299 9.85e-88 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIKJKDOL_02300 6.85e-227 ccpB - - K - - - Transcriptional regulator
HIKJKDOL_02301 4.68e-184 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HIKJKDOL_02302 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HIKJKDOL_02303 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HIKJKDOL_02304 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HIKJKDOL_02305 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HIKJKDOL_02306 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HIKJKDOL_02307 7.41e-45 yyzM - - S - - - protein conserved in bacteria
HIKJKDOL_02308 5.34e-227 yyaD - - S - - - Membrane
HIKJKDOL_02309 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
HIKJKDOL_02310 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HIKJKDOL_02311 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
HIKJKDOL_02312 9.26e-98 - - - S - - - Bacterial PH domain
HIKJKDOL_02313 2.58e-192 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HIKJKDOL_02314 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HIKJKDOL_02315 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HIKJKDOL_02316 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HIKJKDOL_02317 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
HIKJKDOL_02318 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HIKJKDOL_02319 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HIKJKDOL_02320 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HIKJKDOL_02321 1.71e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HIKJKDOL_02322 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
HIKJKDOL_02323 4.54e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HIKJKDOL_02324 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
HIKJKDOL_02325 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIKJKDOL_02326 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIKJKDOL_02327 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HIKJKDOL_02330 2.6e-233 yaaC - - S - - - YaaC-like Protein
HIKJKDOL_02331 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HIKJKDOL_02332 1.03e-315 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HIKJKDOL_02333 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HIKJKDOL_02334 6.75e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HIKJKDOL_02335 9.79e-296 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HIKJKDOL_02337 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
HIKJKDOL_02338 2.43e-150 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
HIKJKDOL_02339 7.7e-278 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
HIKJKDOL_02340 1.44e-127 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
HIKJKDOL_02341 1.55e-110 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HIKJKDOL_02342 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIKJKDOL_02343 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HIKJKDOL_02344 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HIKJKDOL_02345 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
HIKJKDOL_02346 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
HIKJKDOL_02347 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HIKJKDOL_02350 1.82e-41 csfB - - S - - - Inhibitor of sigma-G Gin
HIKJKDOL_02351 1.82e-130 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HIKJKDOL_02352 1.97e-257 yaaN - - P - - - Belongs to the TelA family
HIKJKDOL_02353 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
HIKJKDOL_02354 7.75e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HIKJKDOL_02355 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
HIKJKDOL_02356 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
HIKJKDOL_02357 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HIKJKDOL_02358 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
HIKJKDOL_02359 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
HIKJKDOL_02360 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
HIKJKDOL_02361 1.41e-63 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
HIKJKDOL_02362 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HIKJKDOL_02363 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
HIKJKDOL_02364 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HIKJKDOL_02365 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
HIKJKDOL_02366 1.67e-277 yabE - - T - - - protein conserved in bacteria
HIKJKDOL_02367 2.03e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HIKJKDOL_02368 2.05e-198 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HIKJKDOL_02369 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
HIKJKDOL_02370 5.32e-53 veg - - S - - - protein conserved in bacteria
HIKJKDOL_02371 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
HIKJKDOL_02372 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HIKJKDOL_02373 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HIKJKDOL_02374 1.16e-81 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
HIKJKDOL_02375 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HIKJKDOL_02376 2.58e-309 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HIKJKDOL_02377 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HIKJKDOL_02378 1.45e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HIKJKDOL_02379 8.28e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HIKJKDOL_02380 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
HIKJKDOL_02381 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HIKJKDOL_02382 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
HIKJKDOL_02383 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HIKJKDOL_02384 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HIKJKDOL_02385 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HIKJKDOL_02386 1.91e-66 yabP - - S - - - Sporulation protein YabP
HIKJKDOL_02387 2.58e-138 yabQ - - S - - - spore cortex biosynthesis protein
HIKJKDOL_02388 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HIKJKDOL_02389 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
HIKJKDOL_02392 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
HIKJKDOL_02393 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HIKJKDOL_02394 4e-235 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
HIKJKDOL_02395 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HIKJKDOL_02396 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
HIKJKDOL_02397 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HIKJKDOL_02398 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HIKJKDOL_02399 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HIKJKDOL_02400 1.4e-203 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
HIKJKDOL_02401 4.4e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HIKJKDOL_02402 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HIKJKDOL_02403 5.98e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
HIKJKDOL_02404 2.27e-216 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
HIKJKDOL_02405 3.32e-205 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HIKJKDOL_02406 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HIKJKDOL_02407 2.64e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HIKJKDOL_02408 1.81e-41 yazB - - K - - - transcriptional
HIKJKDOL_02409 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HIKJKDOL_02410 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HIKJKDOL_02411 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HIKJKDOL_02421 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HIKJKDOL_02422 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HIKJKDOL_02423 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
HIKJKDOL_02424 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HIKJKDOL_02425 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
HIKJKDOL_02426 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HIKJKDOL_02427 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HIKJKDOL_02428 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
HIKJKDOL_02429 1.82e-162 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HIKJKDOL_02430 2.59e-112 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HIKJKDOL_02431 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HIKJKDOL_02432 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
HIKJKDOL_02433 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HIKJKDOL_02434 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HIKJKDOL_02435 1.75e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIKJKDOL_02436 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
HIKJKDOL_02437 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
HIKJKDOL_02438 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HIKJKDOL_02439 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HIKJKDOL_02440 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HIKJKDOL_02441 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HIKJKDOL_02442 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HIKJKDOL_02443 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HIKJKDOL_02444 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HIKJKDOL_02445 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIKJKDOL_02446 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIKJKDOL_02447 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
HIKJKDOL_02448 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HIKJKDOL_02449 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HIKJKDOL_02450 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HIKJKDOL_02451 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HIKJKDOL_02452 2.13e-229 ybaC - - S - - - Alpha/beta hydrolase family
HIKJKDOL_02453 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HIKJKDOL_02454 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HIKJKDOL_02455 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HIKJKDOL_02456 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HIKJKDOL_02457 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HIKJKDOL_02458 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HIKJKDOL_02459 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HIKJKDOL_02460 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HIKJKDOL_02461 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HIKJKDOL_02462 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HIKJKDOL_02463 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HIKJKDOL_02464 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HIKJKDOL_02465 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HIKJKDOL_02466 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HIKJKDOL_02467 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HIKJKDOL_02468 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HIKJKDOL_02469 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HIKJKDOL_02470 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HIKJKDOL_02471 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HIKJKDOL_02472 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HIKJKDOL_02473 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HIKJKDOL_02474 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HIKJKDOL_02475 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HIKJKDOL_02476 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HIKJKDOL_02477 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HIKJKDOL_02478 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HIKJKDOL_02479 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HIKJKDOL_02480 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HIKJKDOL_02481 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIKJKDOL_02482 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HIKJKDOL_02483 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIKJKDOL_02484 2.69e-197 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIKJKDOL_02485 1.31e-176 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIKJKDOL_02486 6.15e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HIKJKDOL_02487 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HIKJKDOL_02488 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HIKJKDOL_02489 2.06e-184 ybaJ - - Q - - - Methyltransferase domain
HIKJKDOL_02490 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
HIKJKDOL_02491 9.05e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HIKJKDOL_02492 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HIKJKDOL_02493 1.04e-122 gerD - - - ko:K06294 - ko00000 -
HIKJKDOL_02494 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
HIKJKDOL_02495 5.03e-180 pdaB - - G - - - Polysaccharide deacetylase
HIKJKDOL_02496 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HIKJKDOL_02503 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HIKJKDOL_02504 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HIKJKDOL_02505 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
HIKJKDOL_02507 3.47e-205 ybaS - - S - - - Na -dependent transporter
HIKJKDOL_02508 4.01e-184 ybbA - - S ko:K07017 - ko00000 Putative esterase
HIKJKDOL_02509 3.51e-228 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIKJKDOL_02510 2.88e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIKJKDOL_02511 1.26e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
HIKJKDOL_02512 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
HIKJKDOL_02513 2e-303 ybbC - - S - - - protein conserved in bacteria
HIKJKDOL_02514 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
HIKJKDOL_02515 2.55e-285 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
HIKJKDOL_02516 3.46e-302 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HIKJKDOL_02517 1.82e-192 ybbH - - K - - - transcriptional
HIKJKDOL_02518 6.7e-210 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HIKJKDOL_02519 3.13e-114 ybbJ - - J - - - acetyltransferase
HIKJKDOL_02520 2.43e-100 ybbK - - S - - - Protein of unknown function (DUF523)
HIKJKDOL_02526 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HIKJKDOL_02527 1.3e-150 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HIKJKDOL_02528 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HIKJKDOL_02529 3.41e-291 ybbR - - S - - - protein conserved in bacteria
HIKJKDOL_02530 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HIKJKDOL_02531 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HIKJKDOL_02532 7.11e-225 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HIKJKDOL_02533 6.45e-155 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
HIKJKDOL_02534 1.24e-125 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HIKJKDOL_02535 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HIKJKDOL_02536 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
HIKJKDOL_02537 1.83e-118 ybcF - - P - - - carbonic anhydrase
HIKJKDOL_02539 2.67e-62 - - - - - - - -
HIKJKDOL_02540 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
HIKJKDOL_02541 9.45e-67 - - - K - - - Helix-turn-helix domain
HIKJKDOL_02542 1.81e-255 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
HIKJKDOL_02544 7.24e-304 - - - J - - - 4Fe-4S single cluster domain
HIKJKDOL_02545 0.0 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
HIKJKDOL_02546 8.07e-174 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HIKJKDOL_02547 3.99e-313 skfF - - S - - - ABC transporter
HIKJKDOL_02548 3.88e-118 - - - C - - - HEAT repeats
HIKJKDOL_02549 1.97e-101 - - - CO - - - Thioredoxin-like domain
HIKJKDOL_02550 2.31e-232 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HIKJKDOL_02551 1.39e-157 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
HIKJKDOL_02552 4.22e-214 - - - T - - - His Kinase A (phospho-acceptor) domain
HIKJKDOL_02554 1.68e-179 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
HIKJKDOL_02555 1.49e-192 ybdN - - - - - - -
HIKJKDOL_02556 8.98e-274 ybdO - - S - - - Domain of unknown function (DUF4885)
HIKJKDOL_02557 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HIKJKDOL_02558 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
HIKJKDOL_02559 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
HIKJKDOL_02560 3.71e-193 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
HIKJKDOL_02561 6.76e-308 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
HIKJKDOL_02562 1.11e-54 ybyB - - - - - - -
HIKJKDOL_02563 0.0 ybeC - - E - - - amino acid
HIKJKDOL_02564 7.3e-213 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
HIKJKDOL_02565 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
HIKJKDOL_02566 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
HIKJKDOL_02567 8.93e-220 ybfA - - K - - - FR47-like protein
HIKJKDOL_02568 2.36e-287 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
HIKJKDOL_02571 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
HIKJKDOL_02572 1.02e-205 ybfH - - EG - - - EamA-like transporter family
HIKJKDOL_02573 2.12e-187 ybfI - - K - - - AraC-like ligand binding domain
HIKJKDOL_02574 1.79e-268 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HIKJKDOL_02575 5.64e-227 mpr - - M - - - Belongs to the peptidase S1B family
HIKJKDOL_02577 2.76e-214 - - - S - - - Alpha/beta hydrolase family
HIKJKDOL_02578 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HIKJKDOL_02579 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
HIKJKDOL_02580 3.41e-187 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HIKJKDOL_02581 7.83e-60 ybfN - - - - - - -
HIKJKDOL_02582 9.56e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
HIKJKDOL_02583 6.04e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HIKJKDOL_02584 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HIKJKDOL_02585 3.02e-174 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HIKJKDOL_02586 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
HIKJKDOL_02588 3.08e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HIKJKDOL_02589 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HIKJKDOL_02590 5.26e-233 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
HIKJKDOL_02591 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
HIKJKDOL_02592 3.06e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HIKJKDOL_02593 3.55e-294 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HIKJKDOL_02594 7.01e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
HIKJKDOL_02595 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
HIKJKDOL_02596 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HIKJKDOL_02597 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HIKJKDOL_02598 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HIKJKDOL_02599 7.68e-160 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
HIKJKDOL_02600 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
HIKJKDOL_02601 7.94e-212 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
HIKJKDOL_02602 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
HIKJKDOL_02603 1.92e-213 eamA1 - - EG - - - spore germination
HIKJKDOL_02604 6.42e-161 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIKJKDOL_02605 2.17e-214 ycbM - - T - - - Histidine kinase
HIKJKDOL_02606 3.21e-214 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HIKJKDOL_02607 4.96e-149 - - - S - - - ABC-2 family transporter protein
HIKJKDOL_02608 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
HIKJKDOL_02609 5.22e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
HIKJKDOL_02610 6.36e-173 ycbR - - T - - - vWA found in TerF C terminus
HIKJKDOL_02611 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
HIKJKDOL_02612 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HIKJKDOL_02613 3.61e-158 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HIKJKDOL_02614 2.07e-155 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HIKJKDOL_02615 7.39e-254 ycbU - - E - - - Selenocysteine lyase
HIKJKDOL_02616 2.51e-302 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
HIKJKDOL_02617 6.54e-132 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
HIKJKDOL_02618 2.06e-258 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HIKJKDOL_02619 1.63e-146 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
HIKJKDOL_02620 1.45e-76 - - - S - - - RDD family
HIKJKDOL_02621 1.01e-254 yccF - - K ko:K07039 - ko00000 SEC-C motif
HIKJKDOL_02622 1.69e-210 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HIKJKDOL_02623 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HIKJKDOL_02624 5.41e-171 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HIKJKDOL_02625 1.09e-254 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HIKJKDOL_02626 2.9e-28 yccK - - C - - - Aldo keto reductase
HIKJKDOL_02627 1.29e-182 yccK - - C - - - Aldo keto reductase
HIKJKDOL_02628 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
HIKJKDOL_02629 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HIKJKDOL_02630 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HIKJKDOL_02631 1.53e-122 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HIKJKDOL_02632 3.33e-247 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
HIKJKDOL_02633 6.85e-180 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
HIKJKDOL_02634 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HIKJKDOL_02635 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HIKJKDOL_02636 1.99e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HIKJKDOL_02637 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HIKJKDOL_02638 9.18e-242 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIKJKDOL_02639 2.64e-141 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
HIKJKDOL_02640 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
HIKJKDOL_02641 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
HIKJKDOL_02642 4.1e-176 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
HIKJKDOL_02643 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
HIKJKDOL_02644 2.96e-245 yceH - - P - - - Belongs to the TelA family
HIKJKDOL_02645 2.32e-279 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
HIKJKDOL_02646 1.17e-267 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
HIKJKDOL_02647 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HIKJKDOL_02648 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
HIKJKDOL_02649 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HIKJKDOL_02650 1.16e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HIKJKDOL_02651 6.87e-277 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
HIKJKDOL_02652 0.0 ycgA - - S - - - Membrane
HIKJKDOL_02653 2.72e-105 ycgB - - - - - - -
HIKJKDOL_02654 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
HIKJKDOL_02655 1.19e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HIKJKDOL_02656 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HIKJKDOL_02657 0.0 mdr - - EGP - - - the major facilitator superfamily
HIKJKDOL_02658 3.04e-100 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
HIKJKDOL_02659 2.61e-146 ycgF - - E - - - Lysine exporter protein LysE YggA
HIKJKDOL_02660 3.07e-194 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
HIKJKDOL_02661 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HIKJKDOL_02662 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
HIKJKDOL_02663 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HIKJKDOL_02664 3.09e-139 tmrB - - S - - - AAA domain
HIKJKDOL_02666 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HIKJKDOL_02667 1.29e-186 - - - Q - - - ubiE/COQ5 methyltransferase family
HIKJKDOL_02668 5.4e-226 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
HIKJKDOL_02669 4.48e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
HIKJKDOL_02670 7.76e-187 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
HIKJKDOL_02671 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
HIKJKDOL_02672 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
HIKJKDOL_02673 1.05e-315 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIKJKDOL_02674 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
HIKJKDOL_02675 2.12e-192 ycgQ - - S ko:K08986 - ko00000 membrane
HIKJKDOL_02676 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
HIKJKDOL_02677 3.44e-202 ycgS - - I - - - alpha/beta hydrolase fold
HIKJKDOL_02678 8.53e-245 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HIKJKDOL_02679 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
HIKJKDOL_02680 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
HIKJKDOL_02681 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HIKJKDOL_02682 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HIKJKDOL_02683 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
HIKJKDOL_02684 2.62e-281 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
HIKJKDOL_02685 1.05e-222 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
HIKJKDOL_02686 2.56e-141 - - - M - - - ErfK YbiS YcfS YnhG
HIKJKDOL_02687 2.65e-288 yciC - - S - - - GTPases (G3E family)
HIKJKDOL_02688 1.22e-148 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HIKJKDOL_02689 7.26e-185 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HIKJKDOL_02692 2.83e-99 yckC - - S - - - membrane
HIKJKDOL_02693 1.01e-68 yckD - - S - - - Protein of unknown function (DUF2680)
HIKJKDOL_02694 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HIKJKDOL_02695 4.78e-91 nin - - S - - - Competence protein J (ComJ)
HIKJKDOL_02696 3.23e-99 nucA - - M - - - Deoxyribonuclease NucA/NucB
HIKJKDOL_02697 1.24e-266 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HIKJKDOL_02698 3.24e-126 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
HIKJKDOL_02699 5.63e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
HIKJKDOL_02700 6.05e-86 hxlR - - K - - - transcriptional
HIKJKDOL_02701 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIKJKDOL_02702 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIKJKDOL_02703 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
HIKJKDOL_02704 1.91e-178 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
HIKJKDOL_02705 6.53e-290 - - - EGP - - - Major Facilitator Superfamily
HIKJKDOL_02706 1.8e-123 - - - S - - - YcxB-like protein
HIKJKDOL_02707 3.81e-204 ycxC - - EG - - - EamA-like transporter family
HIKJKDOL_02708 9.36e-317 ycxD - - K - - - GntR family transcriptional regulator
HIKJKDOL_02709 4.76e-145 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
HIKJKDOL_02710 8.71e-148 yczE - - S ko:K07149 - ko00000 membrane
HIKJKDOL_02711 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HIKJKDOL_02712 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HIKJKDOL_02713 7.14e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HIKJKDOL_02714 9.2e-210 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
HIKJKDOL_02715 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HIKJKDOL_02716 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HIKJKDOL_02717 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
HIKJKDOL_02718 1.7e-106 yclD - - - - - - -
HIKJKDOL_02719 1.92e-202 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
HIKJKDOL_02720 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
HIKJKDOL_02721 0.0 yclG - - M - - - Pectate lyase superfamily protein
HIKJKDOL_02723 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
HIKJKDOL_02724 1.22e-289 gerKC - - S ko:K06297 - ko00000 spore germination
HIKJKDOL_02725 4.24e-250 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
HIKJKDOL_02726 3.39e-155 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HIKJKDOL_02727 2.59e-274 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
HIKJKDOL_02728 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIKJKDOL_02729 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HIKJKDOL_02730 2.18e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HIKJKDOL_02733 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HIKJKDOL_02734 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIKJKDOL_02735 7.77e-210 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIKJKDOL_02736 1.61e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HIKJKDOL_02737 3.09e-217 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
HIKJKDOL_02738 0.0 ycnB - - EGP - - - the major facilitator superfamily
HIKJKDOL_02739 9.73e-197 ycnC - - K - - - Transcriptional regulator
HIKJKDOL_02740 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HIKJKDOL_02741 1.68e-60 ycnE - - S - - - Monooxygenase
HIKJKDOL_02742 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HIKJKDOL_02743 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HIKJKDOL_02744 7.68e-310 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HIKJKDOL_02745 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HIKJKDOL_02746 3.37e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
HIKJKDOL_02747 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIKJKDOL_02748 3.05e-138 ycnI - - S - - - protein conserved in bacteria
HIKJKDOL_02749 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
HIKJKDOL_02750 5.18e-139 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HIKJKDOL_02751 5.46e-74 - - - - - - - -
HIKJKDOL_02752 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
HIKJKDOL_02753 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HIKJKDOL_02754 3.77e-269 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
HIKJKDOL_02755 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
HIKJKDOL_02757 6.21e-97 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HIKJKDOL_02758 2.64e-147 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
HIKJKDOL_02759 2.29e-88 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
HIKJKDOL_02761 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
HIKJKDOL_02762 9.39e-182 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
HIKJKDOL_02763 8.88e-270 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
HIKJKDOL_02764 1.65e-188 ycsI - - S - - - Belongs to the D-glutamate cyclase family
HIKJKDOL_02765 8.37e-172 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
HIKJKDOL_02766 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
HIKJKDOL_02767 3.8e-171 kipR - - K - - - Transcriptional regulator
HIKJKDOL_02768 4.18e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
HIKJKDOL_02770 7.67e-66 yczJ - - S - - - biosynthesis
HIKJKDOL_02771 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
HIKJKDOL_02772 3.5e-219 ycsN - - S - - - Oxidoreductase
HIKJKDOL_02773 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
HIKJKDOL_02774 0.0 ydaB - - IQ - - - acyl-CoA ligase
HIKJKDOL_02775 1e-127 ydaC - - Q - - - Methyltransferase domain
HIKJKDOL_02776 3.74e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIKJKDOL_02777 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
HIKJKDOL_02778 8.32e-128 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HIKJKDOL_02779 5.24e-101 ydaG - - S - - - general stress protein
HIKJKDOL_02780 4.39e-177 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HIKJKDOL_02781 3.12e-61 ydzA - - EGP - - - Domain of unknown function (DUF3817)
HIKJKDOL_02782 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
HIKJKDOL_02783 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HIKJKDOL_02784 3.08e-267 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
HIKJKDOL_02785 1.14e-195 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
HIKJKDOL_02786 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
HIKJKDOL_02787 1.93e-304 ydaM - - M - - - Glycosyl transferase family group 2
HIKJKDOL_02788 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
HIKJKDOL_02789 0.0 ydaO - - E - - - amino acid
HIKJKDOL_02790 1.79e-101 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HIKJKDOL_02791 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HIKJKDOL_02792 6.14e-53 - - - - - - - -
HIKJKDOL_02793 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HIKJKDOL_02794 1.67e-42 ydaS - - S - - - membrane
HIKJKDOL_02795 3.73e-99 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HIKJKDOL_02796 4.3e-190 ydbA - - P - - - EcsC protein family
HIKJKDOL_02797 3.3e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
HIKJKDOL_02798 7.58e-79 ydbB - - G - - - Cupin domain
HIKJKDOL_02799 1.28e-82 ydbC - - S - - - Domain of unknown function (DUF4937
HIKJKDOL_02800 2.24e-197 ydbD - - P ko:K07217 - ko00000 Catalase
HIKJKDOL_02801 1.74e-251 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HIKJKDOL_02802 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HIKJKDOL_02803 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
HIKJKDOL_02804 7.33e-289 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HIKJKDOL_02805 1.32e-230 ydbI - - S - - - AI-2E family transporter
HIKJKDOL_02806 2.28e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HIKJKDOL_02807 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HIKJKDOL_02808 9.32e-70 ydbL - - - - - - -
HIKJKDOL_02809 5.87e-277 ydbM - - I - - - acyl-CoA dehydrogenase
HIKJKDOL_02810 1.49e-26 - - - S - - - Fur-regulated basic protein B
HIKJKDOL_02812 1.57e-201 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HIKJKDOL_02813 1.4e-73 ydbP - - CO - - - Thioredoxin
HIKJKDOL_02814 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HIKJKDOL_02815 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HIKJKDOL_02816 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HIKJKDOL_02817 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
HIKJKDOL_02818 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
HIKJKDOL_02819 8.15e-136 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
HIKJKDOL_02820 1.6e-77 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HIKJKDOL_02821 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
HIKJKDOL_02822 1.77e-282 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HIKJKDOL_02823 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HIKJKDOL_02824 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HIKJKDOL_02825 2.46e-183 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
HIKJKDOL_02826 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
HIKJKDOL_02827 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HIKJKDOL_02828 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
HIKJKDOL_02829 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
HIKJKDOL_02830 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HIKJKDOL_02831 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIKJKDOL_02832 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
HIKJKDOL_02836 1.32e-106 ydcG - - S - - - EVE domain
HIKJKDOL_02837 1.54e-101 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HIKJKDOL_02838 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
HIKJKDOL_02839 1.93e-110 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HIKJKDOL_02847 3.99e-96 - - - J - - - Acetyltransferase (GNAT) domain
HIKJKDOL_02848 9.99e-59 - - - - - - - -
HIKJKDOL_02849 1.91e-169 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HIKJKDOL_02850 1.04e-44 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HIKJKDOL_02851 1.21e-52 - - - - - - - -
HIKJKDOL_02855 4.24e-146 ydeA - - S - - - DJ-1/PfpI family
HIKJKDOL_02856 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
HIKJKDOL_02857 1.7e-101 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
HIKJKDOL_02858 8e-181 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HIKJKDOL_02859 6.25e-213 - - - K - - - AraC-like ligand binding domain
HIKJKDOL_02860 2.65e-219 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HIKJKDOL_02861 7.88e-211 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
HIKJKDOL_02862 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HIKJKDOL_02863 3.11e-276 ydeG - - EGP - - - Major facilitator superfamily
HIKJKDOL_02864 3.21e-70 ydeH - - - - - - -
HIKJKDOL_02865 5.75e-135 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
HIKJKDOL_02866 3.64e-142 - - - - - - - -
HIKJKDOL_02867 2.4e-41 - - - S - - - SNARE associated Golgi protein
HIKJKDOL_02868 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
HIKJKDOL_02869 2.44e-110 - - - K - - - Transcriptional regulator C-terminal region
HIKJKDOL_02870 9.01e-195 ydeK - - EG - - - -transporter
HIKJKDOL_02871 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HIKJKDOL_02872 2.49e-95 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
HIKJKDOL_02873 1.37e-134 - - - S ko:K07002 - ko00000 Serine hydrolase
HIKJKDOL_02874 1.02e-72 - - - K - - - HxlR-like helix-turn-helix
HIKJKDOL_02875 4.62e-194 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HIKJKDOL_02876 2.92e-90 ydeP - - K - - - Transcriptional regulator
HIKJKDOL_02877 1e-144 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
HIKJKDOL_02878 1.96e-257 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
HIKJKDOL_02879 9.96e-135 ydeS - - K - - - Transcriptional regulator
HIKJKDOL_02880 1.22e-74 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
HIKJKDOL_02881 1.06e-295 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HIKJKDOL_02882 8.05e-191 - - - J - - - GNAT acetyltransferase
HIKJKDOL_02883 3.05e-207 - - - EG - - - EamA-like transporter family
HIKJKDOL_02884 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HIKJKDOL_02885 4.91e-150 ydfE - - S - - - Flavin reductase like domain
HIKJKDOL_02886 5.24e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HIKJKDOL_02887 1.37e-104 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HIKJKDOL_02889 4.11e-253 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HIKJKDOL_02890 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIKJKDOL_02891 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
HIKJKDOL_02892 9.73e-226 - - - S - - - Alpha/beta hydrolase family
HIKJKDOL_02893 6.79e-152 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HIKJKDOL_02894 2.13e-189 - - - K - - - Bacterial transcription activator, effector binding domain
HIKJKDOL_02895 3.15e-200 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HIKJKDOL_02896 3.45e-145 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
HIKJKDOL_02897 9.49e-239 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HIKJKDOL_02898 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
HIKJKDOL_02899 9.63e-77 ydfQ - - CO - - - Thioredoxin
HIKJKDOL_02900 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
HIKJKDOL_02901 5.33e-39 - - - - - - - -
HIKJKDOL_02903 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
HIKJKDOL_02904 4.44e-160 ydfS - - S - - - Protein of unknown function (DUF421)
HIKJKDOL_02905 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HIKJKDOL_02906 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
HIKJKDOL_02907 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
HIKJKDOL_02908 2.61e-122 ydgC - - K - - - Bacterial regulatory proteins, tetR family
HIKJKDOL_02909 9.94e-71 - - - S - - - DoxX-like family
HIKJKDOL_02910 1.44e-113 yycN - - K - - - Acetyltransferase
HIKJKDOL_02911 3.62e-168 idhA 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
HIKJKDOL_02912 1.16e-151 - - - K - - - helix_turn _helix lactose operon repressor
HIKJKDOL_02913 3.38e-240 xylT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HIKJKDOL_02914 4.53e-132 - - - G - - - Xylose isomerase-like TIM barrel
HIKJKDOL_02915 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
HIKJKDOL_02916 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HIKJKDOL_02917 1.46e-118 - - - S - - - DinB family
HIKJKDOL_02918 2.06e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HIKJKDOL_02919 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
HIKJKDOL_02920 7.5e-146 ydgI - - C - - - nitroreductase
HIKJKDOL_02921 3.29e-90 - - - K - - - Winged helix DNA-binding domain
HIKJKDOL_02922 1.99e-265 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
HIKJKDOL_02923 2.51e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
HIKJKDOL_02924 5.24e-158 ydhC - - K - - - FCD
HIKJKDOL_02925 2.98e-308 ydhD - - M - - - Glycosyl hydrolase
HIKJKDOL_02926 6.49e-288 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HIKJKDOL_02927 1.56e-165 - - - - - - - -
HIKJKDOL_02928 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HIKJKDOL_02929 3.33e-89 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
HIKJKDOL_02931 2.88e-105 - - - K - - - Acetyltransferase (GNAT) domain
HIKJKDOL_02932 2.22e-230 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HIKJKDOL_02933 1.4e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
HIKJKDOL_02934 6.3e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
HIKJKDOL_02935 9.32e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HIKJKDOL_02936 1.44e-68 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HIKJKDOL_02937 1.87e-304 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIKJKDOL_02938 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HIKJKDOL_02939 4.48e-170 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
HIKJKDOL_02940 3.34e-212 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
HIKJKDOL_02941 5.09e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HIKJKDOL_02942 2.75e-270 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
HIKJKDOL_02943 3.44e-202 ydhU - - P ko:K07217 - ko00000 Catalase
HIKJKDOL_02946 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HIKJKDOL_02949 1.82e-229 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HIKJKDOL_02950 2.13e-111 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
HIKJKDOL_02951 1.76e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
HIKJKDOL_02952 1.71e-109 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HIKJKDOL_02953 3.16e-239 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HIKJKDOL_02954 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
HIKJKDOL_02955 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HIKJKDOL_02956 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HIKJKDOL_02957 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HIKJKDOL_02958 3.55e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HIKJKDOL_02959 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
HIKJKDOL_02960 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
HIKJKDOL_02961 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HIKJKDOL_02962 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HIKJKDOL_02964 6.93e-88 - - - KL ko:K06919 - ko00000 Phage plasmid primase P4 family
HIKJKDOL_02965 0.0 dcm 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
HIKJKDOL_02966 1.43e-297 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HIKJKDOL_02968 3.67e-254 - - - V - - - AAA domain (dynein-related subfamily)
HIKJKDOL_02969 0.0 - - - J - - - LlaJI restriction endonuclease
HIKJKDOL_02970 3.73e-11 ydjC - - S - - - Abhydrolase domain containing 18
HIKJKDOL_02971 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
HIKJKDOL_02972 5.04e-257 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HIKJKDOL_02973 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
HIKJKDOL_02974 5.39e-224 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
HIKJKDOL_02975 5.36e-148 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
HIKJKDOL_02976 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HIKJKDOL_02977 3.96e-177 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
HIKJKDOL_02978 1.79e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
HIKJKDOL_02979 1.37e-248 - - - S - - - Ion transport 2 domain protein
HIKJKDOL_02980 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HIKJKDOL_02981 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
HIKJKDOL_02982 1.79e-84 ydjM - - M - - - Lytic transglycolase
HIKJKDOL_02983 1.09e-205 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
HIKJKDOL_02985 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
HIKJKDOL_02986 4.9e-200 - - - I - - - Alpha/beta hydrolase family
HIKJKDOL_02987 7.65e-226 yeaA - - S - - - Protein of unknown function (DUF4003)
HIKJKDOL_02988 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
HIKJKDOL_02989 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HIKJKDOL_02990 6.13e-199 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HIKJKDOL_02991 9.32e-225 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
HIKJKDOL_02992 2.63e-284 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HIKJKDOL_02993 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
HIKJKDOL_02994 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HIKJKDOL_02995 7.14e-117 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HIKJKDOL_02996 0.0 - - - S - - - Domain of unknown function (DUF4179)
HIKJKDOL_02997 1.7e-283 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HIKJKDOL_02998 9.69e-164 yebC - - M - - - Membrane
HIKJKDOL_03000 1.08e-119 yebE - - S - - - UPF0316 protein
HIKJKDOL_03001 3.13e-38 yebG - - S - - - NETI protein
HIKJKDOL_03002 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HIKJKDOL_03003 2.69e-277 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HIKJKDOL_03004 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HIKJKDOL_03005 4.12e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HIKJKDOL_03006 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIKJKDOL_03007 1.91e-166 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIKJKDOL_03008 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIKJKDOL_03009 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HIKJKDOL_03010 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HIKJKDOL_03011 8.88e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HIKJKDOL_03012 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HIKJKDOL_03013 2.07e-300 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HIKJKDOL_03014 5.26e-96 - - - K - - - helix_turn_helix ASNC type
HIKJKDOL_03015 7.95e-290 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
HIKJKDOL_03016 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
HIKJKDOL_03017 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
HIKJKDOL_03018 9.58e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
HIKJKDOL_03019 7.62e-68 yerC - - S - - - protein conserved in bacteria
HIKJKDOL_03020 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
HIKJKDOL_03021 4.48e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HIKJKDOL_03022 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HIKJKDOL_03023 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HIKJKDOL_03024 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
HIKJKDOL_03025 1.22e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
HIKJKDOL_03026 1.88e-159 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
HIKJKDOL_03027 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIKJKDOL_03028 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIKJKDOL_03029 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HIKJKDOL_03030 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIKJKDOL_03031 1.26e-191 yerO - - K - - - Transcriptional regulator
HIKJKDOL_03032 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HIKJKDOL_03033 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HIKJKDOL_03034 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HIKJKDOL_03035 0.0 - - - L - - - Type III restriction enzyme res subunit
HIKJKDOL_03039 1.59e-124 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HIKJKDOL_03041 5.1e-36 - - - - - - - -
HIKJKDOL_03042 3.39e-98 - - - S - - - Protein of unknown function, DUF600
HIKJKDOL_03043 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
HIKJKDOL_03045 2.44e-127 - - - L - - - endonuclease activity
HIKJKDOL_03046 9.33e-160 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
HIKJKDOL_03047 4.2e-33 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
HIKJKDOL_03049 5.41e-275 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
HIKJKDOL_03051 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
HIKJKDOL_03053 7.28e-132 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
HIKJKDOL_03054 4.59e-101 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
HIKJKDOL_03055 3.71e-183 yesF - - GM - - - NAD(P)H-binding
HIKJKDOL_03056 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
HIKJKDOL_03057 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
HIKJKDOL_03058 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
HIKJKDOL_03059 1.19e-130 yesJ - - K - - - Acetyltransferase (GNAT) family
HIKJKDOL_03060 2.56e-132 yesL - - S - - - Protein of unknown function, DUF624
HIKJKDOL_03061 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HIKJKDOL_03062 3.27e-256 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
HIKJKDOL_03063 5.87e-314 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HIKJKDOL_03064 4.08e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HIKJKDOL_03065 8.48e-209 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HIKJKDOL_03066 3.26e-253 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
HIKJKDOL_03067 0.0 yesS - - K - - - Transcriptional regulator
HIKJKDOL_03068 3.15e-165 - - - E - - - GDSL-like Lipase/Acylhydrolase
HIKJKDOL_03069 4.53e-166 yesU - - S - - - Domain of unknown function (DUF1961)
HIKJKDOL_03070 2.83e-145 - - - S - - - Protein of unknown function, DUF624
HIKJKDOL_03071 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
HIKJKDOL_03072 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
HIKJKDOL_03073 6.17e-158 - - - E - - - GDSL-like Lipase/Acylhydrolase
HIKJKDOL_03074 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
HIKJKDOL_03075 0.0 yetA - - - - - - -
HIKJKDOL_03076 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HIKJKDOL_03077 1.18e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
HIKJKDOL_03078 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HIKJKDOL_03079 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HIKJKDOL_03080 1.05e-156 yetF - - S - - - membrane
HIKJKDOL_03081 1.57e-71 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
HIKJKDOL_03082 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIKJKDOL_03083 9.79e-45 - - - - - - - -
HIKJKDOL_03084 3.59e-184 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HIKJKDOL_03085 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
HIKJKDOL_03086 4.23e-134 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
HIKJKDOL_03087 1.3e-38 yetM - - CH - - - FAD binding domain
HIKJKDOL_03088 6.1e-255 yetN - - S - - - Protein of unknown function (DUF3900)
HIKJKDOL_03089 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
HIKJKDOL_03090 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HIKJKDOL_03091 2.15e-190 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
HIKJKDOL_03092 4.79e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
HIKJKDOL_03093 9.79e-232 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
HIKJKDOL_03094 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
HIKJKDOL_03095 9.14e-241 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
HIKJKDOL_03096 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HIKJKDOL_03097 3.84e-170 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HIKJKDOL_03098 6.88e-312 yfnA - - E ko:K03294 - ko00000 amino acid
HIKJKDOL_03099 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HIKJKDOL_03100 5.14e-161 yfmS - - NT - - - chemotaxis protein
HIKJKDOL_03101 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HIKJKDOL_03102 1.08e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
HIKJKDOL_03103 4.14e-89 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
HIKJKDOL_03104 3.59e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
HIKJKDOL_03105 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HIKJKDOL_03106 2.42e-262 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
HIKJKDOL_03107 2.55e-105 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
HIKJKDOL_03108 6.69e-239 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
HIKJKDOL_03109 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HIKJKDOL_03110 2.1e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIKJKDOL_03111 4.72e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIKJKDOL_03112 1.94e-219 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HIKJKDOL_03113 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
HIKJKDOL_03114 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
HIKJKDOL_03115 1.42e-306 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
HIKJKDOL_03116 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HIKJKDOL_03117 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HIKJKDOL_03118 3.96e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HIKJKDOL_03119 5.66e-230 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
HIKJKDOL_03120 1.53e-287 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HIKJKDOL_03121 1.4e-191 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HIKJKDOL_03122 1.13e-274 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HIKJKDOL_03123 2.54e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HIKJKDOL_03124 9.81e-157 yflK - - S - - - protein conserved in bacteria
HIKJKDOL_03125 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
HIKJKDOL_03126 6.9e-27 yflI - - - - - - -
HIKJKDOL_03127 2.1e-65 yflH - - S - - - Protein of unknown function (DUF3243)
HIKJKDOL_03128 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HIKJKDOL_03129 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HIKJKDOL_03130 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HIKJKDOL_03131 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
HIKJKDOL_03132 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
HIKJKDOL_03133 4.89e-31 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
HIKJKDOL_03134 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HIKJKDOL_03135 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
HIKJKDOL_03136 1.02e-171 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
HIKJKDOL_03137 1.77e-159 frp - - C - - - nitroreductase
HIKJKDOL_03138 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HIKJKDOL_03139 5.48e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
HIKJKDOL_03140 6.21e-266 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HIKJKDOL_03141 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
HIKJKDOL_03142 8.37e-108 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIKJKDOL_03143 8.49e-66 yfkI - - S - - - gas vesicle protein
HIKJKDOL_03144 1.13e-182 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HIKJKDOL_03145 1.64e-12 - - - - - - - -
HIKJKDOL_03146 2.7e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HIKJKDOL_03147 5.44e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
HIKJKDOL_03148 3.69e-189 yfkD - - S - - - YfkD-like protein
HIKJKDOL_03149 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
HIKJKDOL_03150 1.76e-283 yfkA - - S - - - YfkB-like domain
HIKJKDOL_03151 3.26e-36 yfjT - - - - - - -
HIKJKDOL_03152 5.95e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
HIKJKDOL_03153 5.62e-193 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HIKJKDOL_03154 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
HIKJKDOL_03155 7.91e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HIKJKDOL_03156 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HIKJKDOL_03157 3e-53 - - - S - - - YfzA-like protein
HIKJKDOL_03158 6.18e-237 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HIKJKDOL_03159 7.56e-108 yfjM - - S - - - Psort location Cytoplasmic, score
HIKJKDOL_03160 2.75e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HIKJKDOL_03161 7.55e-242 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HIKJKDOL_03162 9.43e-262 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HIKJKDOL_03163 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HIKJKDOL_03164 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
HIKJKDOL_03165 2.75e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
HIKJKDOL_03166 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
HIKJKDOL_03167 3.2e-102 - - - S - - - Family of unknown function (DUF5381)
HIKJKDOL_03168 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
HIKJKDOL_03169 4.15e-184 yfjC - - - - - - -
HIKJKDOL_03170 1.94e-270 yfjB - - - - - - -
HIKJKDOL_03171 6.53e-60 yfjA - - S - - - Belongs to the WXG100 family
HIKJKDOL_03172 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HIKJKDOL_03173 3.03e-181 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
HIKJKDOL_03174 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HIKJKDOL_03175 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
HIKJKDOL_03176 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HIKJKDOL_03177 3.34e-83 yfiD3 - - S - - - DoxX
HIKJKDOL_03178 7.28e-209 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
HIKJKDOL_03179 1.28e-228 - - - K ko:K02099 - ko00000,ko03000 AraC-like ligand binding domain
HIKJKDOL_03180 0.0 yfiG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HIKJKDOL_03181 5.47e-234 - - - G - - - Xylose isomerase
HIKJKDOL_03182 5.17e-295 - - - S - - - Oxidoreductase
HIKJKDOL_03184 7.54e-276 baeS - - T - - - Histidine kinase
HIKJKDOL_03185 1.05e-146 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
HIKJKDOL_03186 1.94e-217 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HIKJKDOL_03187 4.18e-264 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HIKJKDOL_03188 8.09e-261 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
HIKJKDOL_03189 1.89e-128 padR - - K - - - transcriptional
HIKJKDOL_03190 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
HIKJKDOL_03191 2.68e-252 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HIKJKDOL_03192 3.3e-138 yfiR - - K - - - Transcriptional regulator
HIKJKDOL_03193 1.91e-266 yfiS - - EGP - - - Major facilitator superfamily
HIKJKDOL_03194 2.7e-126 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
HIKJKDOL_03195 0.0 yfiU - - EGP - - - the major facilitator superfamily
HIKJKDOL_03196 1.27e-104 yfiV - - K - - - transcriptional
HIKJKDOL_03197 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HIKJKDOL_03198 1.1e-230 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HIKJKDOL_03199 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIKJKDOL_03200 1.48e-228 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIKJKDOL_03201 7.61e-215 yfhB - - S - - - PhzF family
HIKJKDOL_03202 2.36e-137 yfhC - - C - - - nitroreductase
HIKJKDOL_03203 8.86e-35 yfhD - - S - - - YfhD-like protein
HIKJKDOL_03205 3.79e-220 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
HIKJKDOL_03206 3.25e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
HIKJKDOL_03207 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
HIKJKDOL_03209 2.45e-268 yfhI - - EGP - - - -transporter
HIKJKDOL_03210 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
HIKJKDOL_03211 8.95e-60 yfhJ - - S - - - WVELL protein
HIKJKDOL_03212 1.7e-117 yfhK - - T - - - Bacterial SH3 domain homologues
HIKJKDOL_03213 4.74e-62 yfhL - - S - - - SdpI/YhfL protein family
HIKJKDOL_03214 3.93e-218 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
HIKJKDOL_03215 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HIKJKDOL_03216 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HIKJKDOL_03217 7.22e-237 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
HIKJKDOL_03218 1.2e-267 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
HIKJKDOL_03219 1.73e-48 yfhS - - - - - - -
HIKJKDOL_03220 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIKJKDOL_03221 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
HIKJKDOL_03222 2.01e-49 ygaB - - S - - - YgaB-like protein
HIKJKDOL_03223 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
HIKJKDOL_03224 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
HIKJKDOL_03225 1.87e-238 ygaE - - S - - - Membrane
HIKJKDOL_03226 1.89e-311 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
HIKJKDOL_03227 8.36e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
HIKJKDOL_03228 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HIKJKDOL_03229 4.8e-73 ygzB - - S - - - UPF0295 protein
HIKJKDOL_03230 4.76e-214 ygxA - - S - - - Nucleotidyltransferase-like
HIKJKDOL_03231 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HIKJKDOL_03248 2.22e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
HIKJKDOL_03249 1.58e-36 - - - - - - - -
HIKJKDOL_03250 1.57e-169 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
HIKJKDOL_03251 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HIKJKDOL_03252 0.0 ygaK - - C - - - Berberine and berberine like
HIKJKDOL_03254 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HIKJKDOL_03255 4.15e-185 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HIKJKDOL_03256 1.78e-219 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
HIKJKDOL_03257 5.86e-190 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HIKJKDOL_03258 9.35e-276 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
HIKJKDOL_03260 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HIKJKDOL_03261 2.79e-102 ygaO - - - - - - -
HIKJKDOL_03262 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
HIKJKDOL_03264 1.92e-147 yhzB - - S - - - B3/4 domain
HIKJKDOL_03265 5.09e-285 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HIKJKDOL_03266 4.79e-226 yhbB - - S - - - Putative amidase domain
HIKJKDOL_03267 6.53e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HIKJKDOL_03268 3.4e-143 yhbD - - K - - - Protein of unknown function (DUF4004)
HIKJKDOL_03269 2.29e-96 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
HIKJKDOL_03270 3.01e-105 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
HIKJKDOL_03271 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
HIKJKDOL_03272 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
HIKJKDOL_03273 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
HIKJKDOL_03274 3.8e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
HIKJKDOL_03275 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
HIKJKDOL_03276 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
HIKJKDOL_03277 3.95e-59 yhcC - - - - - - -
HIKJKDOL_03278 1.03e-69 - - - - - - - -
HIKJKDOL_03279 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
HIKJKDOL_03280 3.38e-158 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HIKJKDOL_03281 1.85e-212 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HIKJKDOL_03282 2.32e-210 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HIKJKDOL_03283 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
HIKJKDOL_03284 1.34e-195 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HIKJKDOL_03285 1.37e-248 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
HIKJKDOL_03286 4.34e-300 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HIKJKDOL_03287 1.69e-114 - - - S - - - Protein of unknown function (DUF2812)
HIKJKDOL_03288 3.22e-65 - - - K - - - Transcriptional regulator PadR-like family
HIKJKDOL_03289 9.11e-67 yhcM - - - - - - -
HIKJKDOL_03290 6.33e-110 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HIKJKDOL_03291 3.96e-227 yhcP - - - - - - -
HIKJKDOL_03292 1.68e-146 yhcQ - - M - - - Spore coat protein
HIKJKDOL_03293 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HIKJKDOL_03294 3.9e-138 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
HIKJKDOL_03295 8.26e-219 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HIKJKDOL_03296 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
HIKJKDOL_03297 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
HIKJKDOL_03298 3.04e-155 yhcW - - S ko:K07025 - ko00000 hydrolase
HIKJKDOL_03299 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HIKJKDOL_03300 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HIKJKDOL_03301 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HIKJKDOL_03302 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HIKJKDOL_03303 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HIKJKDOL_03304 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HIKJKDOL_03305 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
HIKJKDOL_03306 2.29e-273 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
HIKJKDOL_03307 5.68e-148 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIKJKDOL_03308 5.68e-117 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
HIKJKDOL_03309 1.65e-51 yhdB - - S - - - YhdB-like protein
HIKJKDOL_03310 1.25e-72 yhdC - - S - - - Protein of unknown function (DUF3889)
HIKJKDOL_03311 5.63e-274 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HIKJKDOL_03312 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
HIKJKDOL_03313 7.16e-305 ygxB - - M - - - Conserved TM helix
HIKJKDOL_03314 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
HIKJKDOL_03315 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HIKJKDOL_03316 1.82e-200 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HIKJKDOL_03317 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
HIKJKDOL_03318 1.51e-260 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HIKJKDOL_03319 5.51e-206 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIKJKDOL_03320 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
HIKJKDOL_03321 5e-309 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HIKJKDOL_03322 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HIKJKDOL_03323 7.13e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIKJKDOL_03324 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
HIKJKDOL_03325 5.03e-257 yhdL - - S - - - Sigma factor regulator N-terminal
HIKJKDOL_03326 1.08e-111 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HIKJKDOL_03327 9.18e-242 yhdN - - C - - - Aldo keto reductase
HIKJKDOL_03328 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HIKJKDOL_03329 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HIKJKDOL_03330 1.42e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
HIKJKDOL_03331 1.7e-282 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HIKJKDOL_03332 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
HIKJKDOL_03333 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIKJKDOL_03334 5.83e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIKJKDOL_03335 9.03e-173 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HIKJKDOL_03336 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
HIKJKDOL_03337 3.04e-258 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
HIKJKDOL_03338 3.28e-177 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HIKJKDOL_03339 2.14e-195 nodB1 - - G - - - deacetylase
HIKJKDOL_03340 3.69e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HIKJKDOL_03341 1.18e-295 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
HIKJKDOL_03342 1.06e-106 nhaX - - T - - - Belongs to the universal stress protein A family
HIKJKDOL_03343 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HIKJKDOL_03344 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HIKJKDOL_03345 1.84e-140 yheG - - GM - - - NAD(P)H-binding
HIKJKDOL_03346 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
HIKJKDOL_03347 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
HIKJKDOL_03348 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
HIKJKDOL_03349 3.37e-276 yheC - - HJ - - - YheC/D like ATP-grasp
HIKJKDOL_03350 2.4e-258 yheB - - S - - - Belongs to the UPF0754 family
HIKJKDOL_03351 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
HIKJKDOL_03352 6.69e-264 yhaZ - - L - - - DNA alkylation repair enzyme
HIKJKDOL_03353 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
HIKJKDOL_03354 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
HIKJKDOL_03355 1.85e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
HIKJKDOL_03356 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
HIKJKDOL_03358 8.52e-168 yhaR - - I - - - enoyl-CoA hydratase
HIKJKDOL_03359 2.29e-36 - - - S - - - YhzD-like protein
HIKJKDOL_03360 2.27e-214 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HIKJKDOL_03361 2.97e-271 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
HIKJKDOL_03362 2.22e-299 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
HIKJKDOL_03363 0.0 yhaN - - L - - - AAA domain
HIKJKDOL_03364 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
HIKJKDOL_03365 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
HIKJKDOL_03366 2.29e-179 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HIKJKDOL_03367 1.4e-116 yhaK - - S - - - Putative zincin peptidase
HIKJKDOL_03368 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
HIKJKDOL_03369 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
HIKJKDOL_03370 1.74e-54 yhaH - - S - - - YtxH-like protein
HIKJKDOL_03371 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
HIKJKDOL_03372 2.15e-261 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HIKJKDOL_03373 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HIKJKDOL_03374 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
HIKJKDOL_03375 3.11e-272 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HIKJKDOL_03376 7.1e-162 ecsC - - S - - - EcsC protein family
HIKJKDOL_03377 1.32e-292 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HIKJKDOL_03378 4.27e-309 yhfA - - C - - - membrane
HIKJKDOL_03380 5.35e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HIKJKDOL_03381 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HIKJKDOL_03382 3.04e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HIKJKDOL_03383 3.41e-231 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HIKJKDOL_03384 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HIKJKDOL_03385 5.79e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
HIKJKDOL_03386 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
HIKJKDOL_03387 4.17e-235 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HIKJKDOL_03388 1.61e-178 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
HIKJKDOL_03389 2.68e-253 yhfE - - G - - - peptidase M42
HIKJKDOL_03390 3.75e-94 - - - S - - - ASCH
HIKJKDOL_03391 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HIKJKDOL_03392 2.82e-181 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HIKJKDOL_03393 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HIKJKDOL_03394 1.01e-141 yhfK - - GM - - - NmrA-like family
HIKJKDOL_03395 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
HIKJKDOL_03396 2.78e-85 yhfM - - - - - - -
HIKJKDOL_03397 1.12e-306 yhfN - - O - - - Peptidase M48
HIKJKDOL_03398 1.7e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HIKJKDOL_03399 5.98e-100 - - - K - - - acetyltransferase
HIKJKDOL_03400 3.98e-231 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
HIKJKDOL_03401 2.77e-223 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HIKJKDOL_03402 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
HIKJKDOL_03403 1.73e-249 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HIKJKDOL_03404 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
HIKJKDOL_03405 2.09e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HIKJKDOL_03406 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
HIKJKDOL_03407 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
HIKJKDOL_03408 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIKJKDOL_03409 9.84e-45 yhzC - - S - - - IDEAL
HIKJKDOL_03410 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
HIKJKDOL_03411 2.55e-216 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HIKJKDOL_03412 5e-57 yhjA - - S - - - Excalibur calcium-binding domain
HIKJKDOL_03413 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIKJKDOL_03414 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
HIKJKDOL_03415 4.13e-78 yhjD - - - - - - -
HIKJKDOL_03416 5.69e-140 yhjE - - S - - - SNARE associated Golgi protein
HIKJKDOL_03417 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HIKJKDOL_03418 0.0 yhjG - - CH - - - FAD binding domain
HIKJKDOL_03419 8.09e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
HIKJKDOL_03420 1.48e-271 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
HIKJKDOL_03421 1.14e-256 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HIKJKDOL_03422 6.2e-204 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
HIKJKDOL_03423 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
HIKJKDOL_03424 1.07e-239 yhjM - - K - - - Transcriptional regulator
HIKJKDOL_03425 9.74e-257 yhjN - - S ko:K07120 - ko00000 membrane
HIKJKDOL_03426 1.58e-266 - - - EGP - - - Transmembrane secretion effector
HIKJKDOL_03427 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
HIKJKDOL_03428 1.02e-67 yhjQ - - C - - - COG1145 Ferredoxin
HIKJKDOL_03429 7.65e-101 yhjR - - S - - - Rubrerythrin
HIKJKDOL_03430 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
HIKJKDOL_03431 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HIKJKDOL_03432 4e-280 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HIKJKDOL_03433 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
HIKJKDOL_03434 6.4e-65 yisB - - V - - - COG1403 Restriction endonuclease
HIKJKDOL_03435 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
HIKJKDOL_03436 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
HIKJKDOL_03437 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
HIKJKDOL_03438 2.88e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
HIKJKDOL_03439 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
HIKJKDOL_03440 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
HIKJKDOL_03441 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
HIKJKDOL_03442 2.11e-219 cotH - - M ko:K06330 - ko00000 Spore Coat
HIKJKDOL_03443 7.64e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HIKJKDOL_03444 2.05e-74 yisL - - S - - - UPF0344 protein
HIKJKDOL_03445 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HIKJKDOL_03446 1.82e-132 yisN - - S - - - Protein of unknown function (DUF2777)
HIKJKDOL_03447 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HIKJKDOL_03448 2.53e-113 yizA - - S - - - Damage-inducible protein DinB
HIKJKDOL_03449 9.29e-191 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
HIKJKDOL_03450 2.91e-310 yisQ - - V - - - Mate efflux family protein
HIKJKDOL_03451 1.41e-207 yisR - - K - - - Transcriptional regulator
HIKJKDOL_03452 2.14e-234 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HIKJKDOL_03453 4.25e-248 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HIKJKDOL_03454 9.94e-120 yisT - - S - - - DinB family
HIKJKDOL_03455 1.09e-139 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
HIKJKDOL_03456 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HIKJKDOL_03457 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
HIKJKDOL_03458 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HIKJKDOL_03459 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HIKJKDOL_03460 1.54e-292 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
HIKJKDOL_03461 9.51e-185 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
HIKJKDOL_03462 1.61e-154 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
HIKJKDOL_03463 1.75e-179 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
HIKJKDOL_03464 6.62e-140 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIKJKDOL_03465 2.14e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HIKJKDOL_03466 4.1e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HIKJKDOL_03467 1.85e-205 yitH - - K - - - Acetyltransferase (GNAT) domain
HIKJKDOL_03468 3.08e-102 - - - S - - - Acetyltransferase (GNAT) domain
HIKJKDOL_03469 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HIKJKDOL_03470 1.75e-76 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
HIKJKDOL_03471 2.75e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
HIKJKDOL_03472 4.16e-122 - - - - - - - -
HIKJKDOL_03473 1.17e-217 - - - - - - - -
HIKJKDOL_03474 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
HIKJKDOL_03475 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
HIKJKDOL_03476 7.76e-123 - - - - - - - -
HIKJKDOL_03477 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
HIKJKDOL_03478 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
HIKJKDOL_03479 9.13e-202 yitS - - S - - - protein conserved in bacteria
HIKJKDOL_03480 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HIKJKDOL_03481 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
HIKJKDOL_03482 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
HIKJKDOL_03483 1.52e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HIKJKDOL_03484 1.02e-184 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HIKJKDOL_03485 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
HIKJKDOL_03486 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
HIKJKDOL_03487 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
HIKJKDOL_03488 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
HIKJKDOL_03489 8.29e-252 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HIKJKDOL_03490 1.43e-292 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HIKJKDOL_03491 1.27e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HIKJKDOL_03492 1.55e-274 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
HIKJKDOL_03493 1.35e-261 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HIKJKDOL_03494 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
HIKJKDOL_03495 3.01e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HIKJKDOL_03496 2.51e-39 yjzC - - S - - - YjzC-like protein
HIKJKDOL_03497 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
HIKJKDOL_03498 5.69e-181 yjaU - - I - - - carboxylic ester hydrolase activity
HIKJKDOL_03499 5.2e-132 yjaV - - - - - - -
HIKJKDOL_03500 6.4e-235 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
HIKJKDOL_03501 8.86e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
HIKJKDOL_03502 2.67e-38 yjzB - - - - - - -
HIKJKDOL_03503 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HIKJKDOL_03504 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HIKJKDOL_03505 5.49e-192 yjaZ - - O - - - Zn-dependent protease
HIKJKDOL_03506 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HIKJKDOL_03507 2.07e-237 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HIKJKDOL_03508 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
HIKJKDOL_03509 1.04e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIKJKDOL_03510 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIKJKDOL_03511 6.43e-190 yjbA - - S - - - Belongs to the UPF0736 family
HIKJKDOL_03512 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
HIKJKDOL_03513 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HIKJKDOL_03514 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIKJKDOL_03515 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIKJKDOL_03516 1.12e-248 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HIKJKDOL_03517 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HIKJKDOL_03518 7.93e-266 yjbB - - EGP - - - Major Facilitator Superfamily
HIKJKDOL_03519 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIKJKDOL_03520 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HIKJKDOL_03521 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
HIKJKDOL_03522 6.89e-151 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HIKJKDOL_03523 2.53e-281 coiA - - S ko:K06198 - ko00000 Competence protein
HIKJKDOL_03524 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HIKJKDOL_03525 2.68e-28 - - - - - - - -
HIKJKDOL_03527 7.63e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
HIKJKDOL_03528 2.46e-93 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
HIKJKDOL_03529 1.39e-126 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HIKJKDOL_03530 7.02e-128 yjbK - - S - - - protein conserved in bacteria
HIKJKDOL_03531 7.61e-81 yjbL - - S - - - Belongs to the UPF0738 family
HIKJKDOL_03532 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
HIKJKDOL_03533 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HIKJKDOL_03534 4.46e-204 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HIKJKDOL_03535 8.09e-181 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HIKJKDOL_03536 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HIKJKDOL_03537 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HIKJKDOL_03538 1.91e-137 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
HIKJKDOL_03539 5.8e-271 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
HIKJKDOL_03540 1.8e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
HIKJKDOL_03541 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HIKJKDOL_03542 1.77e-237 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HIKJKDOL_03543 1.14e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HIKJKDOL_03544 5.03e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HIKJKDOL_03545 2.56e-104 yjbX - - S - - - Spore coat protein
HIKJKDOL_03546 3.92e-107 cotZ - - S ko:K06344 - ko00000 Spore coat protein
HIKJKDOL_03547 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
HIKJKDOL_03548 2.87e-94 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
HIKJKDOL_03549 8.7e-34 cotW - - - ko:K06341 - ko00000 -
HIKJKDOL_03550 1.18e-71 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
HIKJKDOL_03551 5.03e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
HIKJKDOL_03554 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
HIKJKDOL_03555 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HIKJKDOL_03556 6.31e-51 - - - - - - - -
HIKJKDOL_03557 2.22e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIKJKDOL_03558 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
HIKJKDOL_03559 7.77e-177 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
HIKJKDOL_03560 4.65e-272 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HIKJKDOL_03561 7.47e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HIKJKDOL_03562 1.68e-126 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
HIKJKDOL_03563 1.74e-272 yjcL - - S - - - Protein of unknown function (DUF819)
HIKJKDOL_03566 4.37e-268 - - - S - - - Putative amidase domain
HIKJKDOL_03567 1.52e-68 yjcN - - - - - - -
HIKJKDOL_03570 2.24e-106 - - - L - - - Transposase
HIKJKDOL_03571 5.68e-100 yjcP - - - - - - -
HIKJKDOL_03572 1.01e-65 - - - S - - - YjcQ protein
HIKJKDOL_03573 3.29e-121 yqaS - - L - - - DNA packaging
HIKJKDOL_03574 3.8e-63 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
HIKJKDOL_03575 3.42e-181 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HIKJKDOL_03576 0.000759 - - - - - - - -
HIKJKDOL_03577 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
HIKJKDOL_03578 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HIKJKDOL_03579 8.8e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HIKJKDOL_03580 3.76e-75 yjdF3 - - S - - - Protein of unknown function (DUF2992)
HIKJKDOL_03581 1.79e-117 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HIKJKDOL_03583 1.01e-105 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HIKJKDOL_03584 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
HIKJKDOL_03585 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
HIKJKDOL_03586 7.22e-222 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HIKJKDOL_03588 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
HIKJKDOL_03589 9.03e-108 - - - S - - - Protein of unknown function (DUF2690)
HIKJKDOL_03590 1.13e-29 yjfB - - S - - - Putative motility protein
HIKJKDOL_03591 2.16e-208 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
HIKJKDOL_03592 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
HIKJKDOL_03593 1.22e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
HIKJKDOL_03594 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
HIKJKDOL_03595 1.6e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
HIKJKDOL_03597 1.91e-149 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HIKJKDOL_03599 3.48e-288 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HIKJKDOL_03600 8.74e-280 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HIKJKDOL_03601 1.11e-41 - - - - - - - -
HIKJKDOL_03602 8.69e-189 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
HIKJKDOL_03603 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
HIKJKDOL_03604 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HIKJKDOL_03605 1.09e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
HIKJKDOL_03606 8.91e-121 yjlB - - S - - - Cupin domain
HIKJKDOL_03607 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
HIKJKDOL_03608 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HIKJKDOL_03609 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
HIKJKDOL_03610 6.34e-316 - - - G ko:K03292 - ko00000 symporter YjmB
HIKJKDOL_03611 2.36e-247 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
HIKJKDOL_03612 1.6e-246 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
HIKJKDOL_03613 1.37e-273 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
HIKJKDOL_03614 1.34e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HIKJKDOL_03615 1.37e-289 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
HIKJKDOL_03616 6.95e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
HIKJKDOL_03617 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
HIKJKDOL_03618 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
HIKJKDOL_03619 4.56e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
HIKJKDOL_03620 2.71e-103 yjoA - - S - - - DinB family
HIKJKDOL_03621 6.08e-314 VCP - - O - - - AAA domain (dynein-related subfamily)
HIKJKDOL_03622 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HIKJKDOL_03624 3.18e-50 - - - S - - - YCII-related domain
HIKJKDOL_03625 8.48e-215 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HIKJKDOL_03626 3.87e-80 yjqA - - S - - - Bacterial PH domain
HIKJKDOL_03627 5.99e-143 yjqB - - S - - - Pfam:DUF867
HIKJKDOL_03628 1.85e-203 yjqC - - P ko:K07217 - ko00000 Catalase
HIKJKDOL_03629 2.44e-141 xkdA - - E - - - IrrE N-terminal-like domain
HIKJKDOL_03630 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
HIKJKDOL_03632 4.36e-202 xkdB - - K - - - sequence-specific DNA binding
HIKJKDOL_03633 1.44e-150 xkdC - - L - - - Bacterial dnaA protein
HIKJKDOL_03637 6.41e-107 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HIKJKDOL_03638 1.95e-178 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
HIKJKDOL_03639 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
HIKJKDOL_03640 0.0 yqbA - - S - - - portal protein
HIKJKDOL_03641 1.99e-176 xkdF3 - - L - - - Putative phage serine protease XkdF
HIKJKDOL_03642 1.59e-216 xkdG - - S - - - Phage capsid family
HIKJKDOL_03643 2.06e-85 yqbG - - S - - - Protein of unknown function (DUF3199)
HIKJKDOL_03644 1.05e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
HIKJKDOL_03645 5.84e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
HIKJKDOL_03646 2.87e-101 xkdJ - - - - - - -
HIKJKDOL_03647 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
HIKJKDOL_03648 6.01e-99 xkdM - - S - - - Phage tail tube protein
HIKJKDOL_03649 3.34e-101 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
HIKJKDOL_03650 0.0 xkdO - - L - - - Transglycosylase SLT domain
HIKJKDOL_03651 4.17e-157 xkdP - - S - - - Lysin motif
HIKJKDOL_03652 2.31e-232 xkdQ - - G - - - NLP P60 protein
HIKJKDOL_03653 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
HIKJKDOL_03654 1.89e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
HIKJKDOL_03655 6.23e-244 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HIKJKDOL_03656 3.92e-135 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
HIKJKDOL_03657 8.94e-56 - - - - - - - -
HIKJKDOL_03658 0.0 - - - - - - - -
HIKJKDOL_03659 1.39e-70 xkdW - - S - - - XkdW protein
HIKJKDOL_03660 6.35e-31 xkdX - - - - - - -
HIKJKDOL_03661 5.66e-194 xepA - - - - - - -
HIKJKDOL_03662 2.21e-51 xhlA - - S - - - Haemolysin XhlA
HIKJKDOL_03663 8.12e-53 xhlB - - S - - - SPP1 phage holin
HIKJKDOL_03664 5.76e-212 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
HIKJKDOL_03665 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
HIKJKDOL_03666 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
HIKJKDOL_03667 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
HIKJKDOL_03668 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
HIKJKDOL_03669 6.32e-310 steT - - E ko:K03294 - ko00000 amino acid
HIKJKDOL_03670 8.07e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HIKJKDOL_03671 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HIKJKDOL_03672 4.47e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HIKJKDOL_03674 1.98e-283 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HIKJKDOL_03675 1.93e-177 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
HIKJKDOL_03676 1.63e-195 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
HIKJKDOL_03677 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIKJKDOL_03678 3.02e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIKJKDOL_03679 1.64e-237 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HIKJKDOL_03680 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HIKJKDOL_03682 1.66e-225 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
HIKJKDOL_03683 2.4e-257 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HIKJKDOL_03684 9.9e-208 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HIKJKDOL_03685 4.88e-236 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HIKJKDOL_03686 1.34e-259 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
HIKJKDOL_03687 1.78e-205 ykgA - - E - - - Amidinotransferase
HIKJKDOL_03688 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
HIKJKDOL_03689 5.35e-289 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HIKJKDOL_03690 1.15e-13 - - - - - - - -
HIKJKDOL_03691 1.13e-166 ykjA - - S - - - Protein of unknown function (DUF421)
HIKJKDOL_03692 5.07e-125 ykkA - - S - - - Protein of unknown function (DUF664)
HIKJKDOL_03693 3.59e-128 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HIKJKDOL_03694 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
HIKJKDOL_03695 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
HIKJKDOL_03696 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HIKJKDOL_03697 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HIKJKDOL_03698 1.6e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HIKJKDOL_03699 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
HIKJKDOL_03700 1.66e-96 ohrR - - K - - - COG1846 Transcriptional regulators
HIKJKDOL_03701 4.72e-93 ohrB - - O - - - Organic hydroperoxide resistance protein
HIKJKDOL_03702 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
HIKJKDOL_03703 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HIKJKDOL_03704 1.43e-223 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HIKJKDOL_03705 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HIKJKDOL_03706 3.12e-174 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HIKJKDOL_03707 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HIKJKDOL_03708 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HIKJKDOL_03709 1.16e-140 ykoF - - S - - - YKOF-related Family
HIKJKDOL_03710 8.68e-159 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIKJKDOL_03711 3.5e-306 ykoH - - T - - - Histidine kinase
HIKJKDOL_03712 2.52e-141 ykoI - - S - - - Peptidase propeptide and YPEB domain
HIKJKDOL_03713 5.28e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
HIKJKDOL_03714 1.45e-08 - - - - - - - -
HIKJKDOL_03716 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
HIKJKDOL_03717 1.49e-70 tnrA - - K - - - transcriptional
HIKJKDOL_03718 1.63e-25 - - - - - - - -
HIKJKDOL_03719 3.04e-36 ykoL - - - - - - -
HIKJKDOL_03720 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
HIKJKDOL_03721 3.14e-277 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HIKJKDOL_03722 1.44e-128 ykoP - - G - - - polysaccharide deacetylase
HIKJKDOL_03723 5.08e-197 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HIKJKDOL_03724 0.0 ykoS - - - - - - -
HIKJKDOL_03725 9.49e-238 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
HIKJKDOL_03726 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
HIKJKDOL_03727 1.25e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HIKJKDOL_03728 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
HIKJKDOL_03729 1.71e-143 ykoX - - S - - - membrane-associated protein
HIKJKDOL_03730 4.63e-227 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HIKJKDOL_03731 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIKJKDOL_03732 2.19e-217 rsgI - - S - - - Anti-sigma factor N-terminus
HIKJKDOL_03733 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
HIKJKDOL_03734 1.27e-158 ykrK - - S - - - Domain of unknown function (DUF1836)
HIKJKDOL_03735 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HIKJKDOL_03736 4.28e-309 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
HIKJKDOL_03738 1.77e-28 ykzE - - - - - - -
HIKJKDOL_03739 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
HIKJKDOL_03740 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HIKJKDOL_03741 1.53e-112 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HIKJKDOL_03743 2.2e-251 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HIKJKDOL_03744 3.36e-291 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HIKJKDOL_03745 1.15e-192 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HIKJKDOL_03746 2.29e-294 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HIKJKDOL_03747 3.79e-292 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HIKJKDOL_03748 2.93e-174 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HIKJKDOL_03749 1.84e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HIKJKDOL_03750 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HIKJKDOL_03751 3.6e-67 - - - S - - - Protein of unknown function (DUF1232)
HIKJKDOL_03753 1.18e-94 eag - - - - - - -
HIKJKDOL_03754 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HIKJKDOL_03755 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
HIKJKDOL_03756 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
HIKJKDOL_03757 1.65e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
HIKJKDOL_03758 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
HIKJKDOL_03759 2.26e-225 ykvI - - S - - - membrane
HIKJKDOL_03760 1.58e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HIKJKDOL_03761 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
HIKJKDOL_03762 3.56e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HIKJKDOL_03763 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HIKJKDOL_03764 2.8e-81 ykvN - - K - - - Transcriptional regulator
HIKJKDOL_03765 3.81e-172 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HIKJKDOL_03766 1.82e-273 - - - M - - - Glycosyl transferases group 1
HIKJKDOL_03767 7.56e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
HIKJKDOL_03768 3.02e-205 - - - G - - - Glycosyl hydrolases family 18
HIKJKDOL_03769 2.67e-62 ykvR - - S - - - Protein of unknown function (DUF3219)
HIKJKDOL_03770 5.43e-35 ykvS - - S - - - protein conserved in bacteria
HIKJKDOL_03771 2.6e-39 - - - - - - - -
HIKJKDOL_03772 5.26e-141 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
HIKJKDOL_03773 4.55e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HIKJKDOL_03774 5.57e-115 stoA - - CO - - - thiol-disulfide
HIKJKDOL_03775 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
HIKJKDOL_03776 3.99e-09 - - - - - - - -
HIKJKDOL_03777 1.93e-264 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
HIKJKDOL_03778 3.82e-229 ykvZ - - K - - - Transcriptional regulator
HIKJKDOL_03780 1.14e-166 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
HIKJKDOL_03781 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HIKJKDOL_03782 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
HIKJKDOL_03783 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HIKJKDOL_03784 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
HIKJKDOL_03785 4.3e-257 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
HIKJKDOL_03786 1.59e-164 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIKJKDOL_03787 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HIKJKDOL_03788 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HIKJKDOL_03789 5.36e-172 ykwD - - J - - - protein with SCP PR1 domains
HIKJKDOL_03790 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HIKJKDOL_03791 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HIKJKDOL_03792 5.32e-286 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HIKJKDOL_03793 1.05e-22 - - - - - - - -
HIKJKDOL_03794 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
HIKJKDOL_03795 3.71e-110 ykyB - - S - - - YkyB-like protein
HIKJKDOL_03796 1.04e-304 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HIKJKDOL_03797 4.8e-114 ykuD - - S - - - protein conserved in bacteria
HIKJKDOL_03798 9.98e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
HIKJKDOL_03799 1.83e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIKJKDOL_03800 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
HIKJKDOL_03801 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
HIKJKDOL_03802 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
HIKJKDOL_03803 7.83e-38 ykzF - - S - - - Antirepressor AbbA
HIKJKDOL_03804 5.15e-100 ykuL - - S - - - CBS domain
HIKJKDOL_03805 6.52e-216 ccpC - - K - - - Transcriptional regulator
HIKJKDOL_03806 1.18e-108 - - - C ko:K03839 - ko00000 Flavodoxin domain
HIKJKDOL_03807 3.66e-224 ykuO - - - - - - -
HIKJKDOL_03808 1.03e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
HIKJKDOL_03809 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HIKJKDOL_03810 8.95e-273 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HIKJKDOL_03811 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
HIKJKDOL_03812 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
HIKJKDOL_03813 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
HIKJKDOL_03814 4.94e-103 ykuV - - CO - - - thiol-disulfide
HIKJKDOL_03815 4.71e-122 rok - - K - - - Repressor of ComK
HIKJKDOL_03816 6.97e-200 yknT - - - ko:K06437 - ko00000 -
HIKJKDOL_03817 5.33e-141 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HIKJKDOL_03818 5.12e-243 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HIKJKDOL_03819 1.05e-313 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
HIKJKDOL_03820 4.89e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
HIKJKDOL_03821 3.83e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
HIKJKDOL_03822 6.92e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HIKJKDOL_03823 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HIKJKDOL_03824 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HIKJKDOL_03825 1.6e-151 yknW - - S - - - Yip1 domain
HIKJKDOL_03826 5.75e-234 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HIKJKDOL_03827 6.1e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HIKJKDOL_03828 1.92e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HIKJKDOL_03829 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
HIKJKDOL_03830 8.21e-215 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
HIKJKDOL_03831 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HIKJKDOL_03832 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HIKJKDOL_03833 5.43e-52 ykoA - - - - - - -
HIKJKDOL_03834 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HIKJKDOL_03835 1.17e-214 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HIKJKDOL_03836 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
HIKJKDOL_03837 1.09e-18 - - - S - - - Uncharacterized protein YkpC
HIKJKDOL_03838 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
HIKJKDOL_03839 7.55e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
HIKJKDOL_03840 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HIKJKDOL_03841 3.42e-198 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
HIKJKDOL_03842 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
HIKJKDOL_03843 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HIKJKDOL_03844 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIKJKDOL_03845 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
HIKJKDOL_03846 2.03e-187 ykrA - - S - - - hydrolases of the HAD superfamily
HIKJKDOL_03847 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HIKJKDOL_03848 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HIKJKDOL_03849 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
HIKJKDOL_03850 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HIKJKDOL_03851 1.75e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HIKJKDOL_03852 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HIKJKDOL_03853 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HIKJKDOL_03854 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
HIKJKDOL_03855 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
HIKJKDOL_03856 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
HIKJKDOL_03857 5.28e-152 yktB - - S - - - Belongs to the UPF0637 family
HIKJKDOL_03858 4.48e-35 ykzI - - - - - - -
HIKJKDOL_03859 9.48e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
HIKJKDOL_03860 2.02e-98 ykzC - - S - - - Acetyltransferase (GNAT) family
HIKJKDOL_03861 9.64e-219 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HIKJKDOL_03862 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
HIKJKDOL_03863 0.0 ylaA - - - - - - -
HIKJKDOL_03864 1.44e-56 ylaB - - - - - - -
HIKJKDOL_03865 3.56e-115 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HIKJKDOL_03867 9.96e-57 ylaE - - - - - - -
HIKJKDOL_03868 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
HIKJKDOL_03869 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HIKJKDOL_03870 4.4e-63 ylaH - - S - - - YlaH-like protein
HIKJKDOL_03871 8.92e-44 ylaI - - S - - - protein conserved in bacteria
HIKJKDOL_03872 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HIKJKDOL_03873 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
HIKJKDOL_03874 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HIKJKDOL_03875 4.25e-220 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HIKJKDOL_03876 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
HIKJKDOL_03877 2.57e-273 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HIKJKDOL_03878 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HIKJKDOL_03879 1.21e-213 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HIKJKDOL_03880 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HIKJKDOL_03881 5.85e-253 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HIKJKDOL_03882 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HIKJKDOL_03883 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HIKJKDOL_03884 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HIKJKDOL_03885 1.21e-213 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
HIKJKDOL_03886 1.61e-81 ylbA - - S - - - YugN-like family
HIKJKDOL_03887 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
HIKJKDOL_03888 4.39e-256 ylbC - - S - - - protein with SCP PR1 domains
HIKJKDOL_03889 3.24e-89 ylbD - - S - - - Putative coat protein
HIKJKDOL_03890 3.5e-48 ylbE - - S - - - YlbE-like protein
HIKJKDOL_03891 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
HIKJKDOL_03892 5.1e-51 ylbG - - S - - - UPF0298 protein
HIKJKDOL_03893 3.51e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
HIKJKDOL_03894 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HIKJKDOL_03895 5.5e-282 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
HIKJKDOL_03896 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HIKJKDOL_03897 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HIKJKDOL_03898 1.99e-299 ylbM - - S - - - Belongs to the UPF0348 family
HIKJKDOL_03900 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
HIKJKDOL_03901 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HIKJKDOL_03902 1.35e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HIKJKDOL_03903 1.33e-115 ylbP - - K - - - n-acetyltransferase
HIKJKDOL_03904 3.92e-215 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HIKJKDOL_03905 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HIKJKDOL_03906 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HIKJKDOL_03907 1.94e-217 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HIKJKDOL_03908 3.42e-68 ftsL - - D - - - Essential cell division protein
HIKJKDOL_03909 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HIKJKDOL_03910 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
HIKJKDOL_03911 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HIKJKDOL_03912 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HIKJKDOL_03913 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HIKJKDOL_03914 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HIKJKDOL_03915 3.84e-257 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HIKJKDOL_03916 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
HIKJKDOL_03917 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HIKJKDOL_03918 4.5e-142 ylxW - - S - - - protein conserved in bacteria
HIKJKDOL_03919 9.87e-122 ylxX - - S - - - protein conserved in bacteria
HIKJKDOL_03920 4.57e-72 sbp - - S - - - small basic protein
HIKJKDOL_03921 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HIKJKDOL_03922 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HIKJKDOL_03923 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
HIKJKDOL_03924 1.06e-220 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HIKJKDOL_03925 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIKJKDOL_03926 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIKJKDOL_03927 1.57e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HIKJKDOL_03928 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
HIKJKDOL_03929 3.58e-51 ylmC - - S - - - sporulation protein
HIKJKDOL_03930 7.53e-203 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
HIKJKDOL_03931 3.15e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HIKJKDOL_03932 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HIKJKDOL_03933 1.74e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
HIKJKDOL_03934 2.03e-176 ylmH - - S - - - conserved protein, contains S4-like domain
HIKJKDOL_03935 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
HIKJKDOL_03936 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HIKJKDOL_03937 1.58e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
HIKJKDOL_03938 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HIKJKDOL_03939 2.38e-223 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HIKJKDOL_03940 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HIKJKDOL_03941 9.12e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
HIKJKDOL_03942 4.04e-211 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HIKJKDOL_03943 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HIKJKDOL_03944 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HIKJKDOL_03945 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
HIKJKDOL_03946 4.31e-182 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HIKJKDOL_03947 1.05e-221 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HIKJKDOL_03948 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HIKJKDOL_03949 8.96e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HIKJKDOL_03951 4.19e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
HIKJKDOL_03952 1.21e-228 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
HIKJKDOL_03953 4.34e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
HIKJKDOL_03954 1.59e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HIKJKDOL_03955 7.18e-186 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
HIKJKDOL_03956 1.45e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
HIKJKDOL_03957 1.87e-107 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
HIKJKDOL_03958 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
HIKJKDOL_03959 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
HIKJKDOL_03960 1.19e-201 yloC - - S - - - stress-induced protein
HIKJKDOL_03961 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
HIKJKDOL_03962 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HIKJKDOL_03963 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HIKJKDOL_03964 7.28e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HIKJKDOL_03965 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HIKJKDOL_03966 4.8e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HIKJKDOL_03967 4.98e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HIKJKDOL_03968 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HIKJKDOL_03969 2.16e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HIKJKDOL_03970 3.54e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HIKJKDOL_03971 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HIKJKDOL_03972 3.92e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HIKJKDOL_03973 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HIKJKDOL_03974 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HIKJKDOL_03975 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HIKJKDOL_03976 3.65e-78 yloU - - S - - - protein conserved in bacteria
HIKJKDOL_03977 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
HIKJKDOL_03978 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
HIKJKDOL_03979 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
HIKJKDOL_03980 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HIKJKDOL_03981 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HIKJKDOL_03982 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HIKJKDOL_03983 1.53e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
HIKJKDOL_03984 1.17e-165 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HIKJKDOL_03985 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HIKJKDOL_03986 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HIKJKDOL_03987 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HIKJKDOL_03988 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HIKJKDOL_03989 2.56e-111 - - - - - - - -
HIKJKDOL_03990 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HIKJKDOL_03991 1.96e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HIKJKDOL_03992 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HIKJKDOL_03993 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HIKJKDOL_03994 3.41e-80 ylqD - - S - - - YlqD protein
HIKJKDOL_03995 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HIKJKDOL_03996 3.99e-176 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HIKJKDOL_03997 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HIKJKDOL_03998 2.32e-199 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HIKJKDOL_03999 5.83e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIKJKDOL_04000 0.0 ylqG - - - - - - -
HIKJKDOL_04001 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
HIKJKDOL_04002 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HIKJKDOL_04003 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HIKJKDOL_04004 2.66e-217 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
HIKJKDOL_04005 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HIKJKDOL_04006 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HIKJKDOL_04007 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
HIKJKDOL_04008 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HIKJKDOL_04009 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HIKJKDOL_04010 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HIKJKDOL_04011 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HIKJKDOL_04012 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
HIKJKDOL_04013 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
HIKJKDOL_04014 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
HIKJKDOL_04015 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HIKJKDOL_04016 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
HIKJKDOL_04017 1.22e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HIKJKDOL_04018 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
HIKJKDOL_04019 2.93e-83 ylxF - - S - - - MgtE intracellular N domain
HIKJKDOL_04020 3.14e-312 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
HIKJKDOL_04021 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
HIKJKDOL_04022 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
HIKJKDOL_04023 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
HIKJKDOL_04024 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HIKJKDOL_04025 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HIKJKDOL_04026 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
HIKJKDOL_04027 1.12e-136 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
HIKJKDOL_04028 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
HIKJKDOL_04029 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
HIKJKDOL_04030 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
HIKJKDOL_04031 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HIKJKDOL_04032 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HIKJKDOL_04033 5.65e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
HIKJKDOL_04034 1.49e-198 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
HIKJKDOL_04035 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HIKJKDOL_04036 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
HIKJKDOL_04037 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
HIKJKDOL_04038 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HIKJKDOL_04039 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HIKJKDOL_04040 9.34e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIKJKDOL_04041 6.62e-99 ylxL - - - - - - -
HIKJKDOL_04042 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HIKJKDOL_04043 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HIKJKDOL_04044 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HIKJKDOL_04045 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HIKJKDOL_04046 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HIKJKDOL_04047 1.36e-177 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HIKJKDOL_04048 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HIKJKDOL_04049 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HIKJKDOL_04050 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HIKJKDOL_04051 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIKJKDOL_04052 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HIKJKDOL_04053 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HIKJKDOL_04054 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
HIKJKDOL_04055 6.16e-63 ylxQ - - J - - - ribosomal protein
HIKJKDOL_04056 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HIKJKDOL_04057 7.83e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
HIKJKDOL_04058 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HIKJKDOL_04059 6.04e-220 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HIKJKDOL_04060 1.1e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HIKJKDOL_04061 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HIKJKDOL_04062 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HIKJKDOL_04063 4.33e-234 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
HIKJKDOL_04064 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
HIKJKDOL_04065 1.53e-56 ymxH - - S - - - YlmC YmxH family
HIKJKDOL_04066 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
HIKJKDOL_04067 3.33e-140 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HIKJKDOL_04068 2.76e-246 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HIKJKDOL_04069 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HIKJKDOL_04070 1.57e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HIKJKDOL_04071 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIKJKDOL_04072 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
HIKJKDOL_04073 4.94e-44 - - - S - - - YlzJ-like protein
HIKJKDOL_04074 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HIKJKDOL_04075 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
HIKJKDOL_04076 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HIKJKDOL_04077 1.35e-298 albE - - S - - - Peptidase M16
HIKJKDOL_04078 2.37e-309 ymfH - - S - - - zinc protease
HIKJKDOL_04079 7.38e-167 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HIKJKDOL_04080 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
HIKJKDOL_04081 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
HIKJKDOL_04082 3.78e-171 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
HIKJKDOL_04083 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HIKJKDOL_04084 6.15e-299 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HIKJKDOL_04085 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HIKJKDOL_04086 8.43e-282 pbpX - - V - - - Beta-lactamase
HIKJKDOL_04087 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HIKJKDOL_04088 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
HIKJKDOL_04089 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
HIKJKDOL_04090 5.01e-254 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HIKJKDOL_04091 1.02e-278 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HIKJKDOL_04092 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HIKJKDOL_04093 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
HIKJKDOL_04094 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
HIKJKDOL_04095 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HIKJKDOL_04096 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HIKJKDOL_04097 7.19e-93 - - - S - - - Regulatory protein YrvL
HIKJKDOL_04099 1.38e-127 ymcC - - S - - - Membrane
HIKJKDOL_04100 2.94e-141 pksA - - K - - - Transcriptional regulator
HIKJKDOL_04101 4.02e-167 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
HIKJKDOL_04102 5.32e-208 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
HIKJKDOL_04103 2.08e-239 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
HIKJKDOL_04104 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
HIKJKDOL_04105 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
HIKJKDOL_04106 5.31e-304 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HIKJKDOL_04107 9.7e-314 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
HIKJKDOL_04108 2.48e-184 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
HIKJKDOL_04109 2.69e-177 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
HIKJKDOL_04110 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
HIKJKDOL_04111 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
HIKJKDOL_04112 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
HIKJKDOL_04113 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
HIKJKDOL_04114 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
HIKJKDOL_04115 2.39e-295 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HIKJKDOL_04116 1.14e-80 ymzB - - - - - - -
HIKJKDOL_04117 3.79e-207 - - - S - - - Metallo-beta-lactamase superfamily
HIKJKDOL_04118 2.17e-234 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
HIKJKDOL_04121 0.000231 - - - L - - - Phage terminase small Subunit
HIKJKDOL_04124 3.23e-56 - - - S - - - endonuclease activity
HIKJKDOL_04125 3.22e-164 - - - S - - - Phage Terminase
HIKJKDOL_04126 6.42e-132 - - - S - - - Phage portal protein
HIKJKDOL_04127 3.46e-64 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
HIKJKDOL_04128 1.58e-108 - - - S - - - Phage capsid family
HIKJKDOL_04130 1.9e-05 - - - S - - - Phage gp6-like head-tail connector protein
HIKJKDOL_04134 2.66e-52 - - - S - - - Phage tail tube protein
HIKJKDOL_04136 1.12e-174 - - - D - - - Phage tail tape measure protein
HIKJKDOL_04137 4e-240 - - - S - - - Phage tail protein
HIKJKDOL_04138 9.69e-159 - - - S - - - peptidoglycan catabolic process
HIKJKDOL_04140 9.9e-86 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
HIKJKDOL_04145 5.18e-146 - - - M - - - Glycosyl hydrolases family 25
HIKJKDOL_04146 7.4e-122 - - - S - - - Phage integrase family
HIKJKDOL_04147 8.47e-224 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
HIKJKDOL_04148 1.04e-85 - - - S - - - Immunity protein 70
HIKJKDOL_04149 2.06e-31 - - - S - - - Domain of unknown function (DUF4935)
HIKJKDOL_04157 5.48e-70 - - - L - - - Domain of unknown function (DUF1738)
HIKJKDOL_04158 6.66e-181 - - - S - - - DNA gyrase/topoisomerase IV, subunit A
HIKJKDOL_04159 4.95e-230 - - - S - - - DNA gyrase B
HIKJKDOL_04160 5.92e-17 - - - S - - - Replication initiator protein A (RepA) N-terminus
HIKJKDOL_04169 7.95e-18 - - - F - - - Guanylate kinase homologues.
HIKJKDOL_04173 0.0 - - - S - - - Bacterial DNA polymerase III alpha subunit
HIKJKDOL_04177 4.61e-60 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIKJKDOL_04183 9.03e-15 M1-624 - - K - - - Transcriptional regulator
HIKJKDOL_04184 2.46e-101 - - - S - - - exonuclease activity
HIKJKDOL_04186 6.78e-111 - - - S - - - DNA primase activity
HIKJKDOL_04187 5.47e-133 - - - S - - - DNA helicase activity
HIKJKDOL_04188 1.21e-11 - - - - - - - -
HIKJKDOL_04191 3.01e-52 - - - - - - - -
HIKJKDOL_04194 7.45e-130 - - - S - - - Ribonucleotide reductase, small chain
HIKJKDOL_04195 0.0 - - - S - - - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
HIKJKDOL_04196 7.68e-80 - - - S - - - AAA domain
HIKJKDOL_04199 2.56e-62 - - - F - - - Nucleoside 2-deoxyribosyltransferase
HIKJKDOL_04203 6.29e-43 yxcD - - S - - - Protein of unknown function (DUF2653)
HIKJKDOL_04205 5.79e-19 - - - - - - - -
HIKJKDOL_04206 1.23e-52 - - - S ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphoribosyl-ATP pyrophosphohydrolase
HIKJKDOL_04210 7.94e-94 - - - L - - - integrase family
HIKJKDOL_04213 4.22e-23 - - - S - - - 3D domain
HIKJKDOL_04214 2.33e-67 - - - S - - - DNA ligase (ATP) activity
HIKJKDOL_04216 1.67e-102 - - - - - - - -
HIKJKDOL_04218 5.31e-174 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)