ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HEBBHNLP_00001 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HEBBHNLP_00002 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBBHNLP_00003 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBBHNLP_00004 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBBHNLP_00005 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBBHNLP_00006 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
HEBBHNLP_00007 2.89e-82 yngL - - S - - - Protein of unknown function (DUF1360)
HEBBHNLP_00008 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
HEBBHNLP_00009 3.09e-267 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
HEBBHNLP_00010 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HEBBHNLP_00011 8.43e-316 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
HEBBHNLP_00012 2.4e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
HEBBHNLP_00013 9.56e-212 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
HEBBHNLP_00014 7.04e-174 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
HEBBHNLP_00015 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HEBBHNLP_00016 3.01e-295 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
HEBBHNLP_00017 2.01e-134 yngC - - S - - - membrane-associated protein
HEBBHNLP_00018 3.2e-209 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HEBBHNLP_00019 4.94e-103 yngA - - S - - - membrane
HEBBHNLP_00020 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HEBBHNLP_00021 9.85e-317 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
HEBBHNLP_00023 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
HEBBHNLP_00024 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
HEBBHNLP_00025 1.06e-75 ynfC - - - - - - -
HEBBHNLP_00026 1.82e-18 - - - - - - - -
HEBBHNLP_00027 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEBBHNLP_00028 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEBBHNLP_00029 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
HEBBHNLP_00030 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HEBBHNLP_00031 2.57e-64 yneR - - S - - - Belongs to the HesB IscA family
HEBBHNLP_00032 4.68e-71 yneQ - - - - - - -
HEBBHNLP_00033 4.02e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
HEBBHNLP_00034 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
HEBBHNLP_00036 9.26e-10 - - - S - - - Fur-regulated basic protein B
HEBBHNLP_00037 7.25e-118 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HEBBHNLP_00038 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HEBBHNLP_00039 3.27e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
HEBBHNLP_00040 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
HEBBHNLP_00041 2.35e-84 cotM - - O ko:K06335 - ko00000 Spore coat protein
HEBBHNLP_00042 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
HEBBHNLP_00043 5.07e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
HEBBHNLP_00044 2.12e-77 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
HEBBHNLP_00045 1.38e-163 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
HEBBHNLP_00046 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
HEBBHNLP_00047 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
HEBBHNLP_00048 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
HEBBHNLP_00049 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HEBBHNLP_00050 1.15e-43 ynzC - - S - - - UPF0291 protein
HEBBHNLP_00051 2.68e-143 yneB - - L - - - resolvase
HEBBHNLP_00052 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HEBBHNLP_00053 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HEBBHNLP_00054 1.43e-100 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HEBBHNLP_00055 1.09e-95 yndM - - S - - - Protein of unknown function (DUF2512)
HEBBHNLP_00056 6.31e-173 yndL - - S - - - Replication protein
HEBBHNLP_00058 0.0 yndJ - - S - - - YndJ-like protein
HEBBHNLP_00059 5.74e-148 - - - S - - - Domain of unknown function (DUF4166)
HEBBHNLP_00060 3.43e-194 yndG - - S - - - DoxX-like family
HEBBHNLP_00061 7.59e-287 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
HEBBHNLP_00062 1.26e-246 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
HEBBHNLP_00063 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HEBBHNLP_00066 6.07e-102 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
HEBBHNLP_00067 8.92e-96 - - - - - - - -
HEBBHNLP_00068 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
HEBBHNLP_00071 5.34e-166 - - - S - - - Domain of unknown function, YrpD
HEBBHNLP_00073 1.12e-209 - - - S - - - Thymidylate synthase
HEBBHNLP_00076 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
HEBBHNLP_00077 5.49e-107 - - - S - - - Protein of unknown function (DUF2691)
HEBBHNLP_00078 1.45e-279 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEBBHNLP_00079 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEBBHNLP_00080 7.18e-145 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
HEBBHNLP_00081 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
HEBBHNLP_00082 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
HEBBHNLP_00083 6.1e-276 xylR - - GK - - - ROK family
HEBBHNLP_00084 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HEBBHNLP_00085 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
HEBBHNLP_00087 3.11e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HEBBHNLP_00089 6.63e-76 ynaF - - - - - - -
HEBBHNLP_00090 6.82e-141 - - - S - - - Domain of unknown function (DUF3885)
HEBBHNLP_00091 1.74e-33 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HEBBHNLP_00092 2.38e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HEBBHNLP_00093 2.24e-37 - - - S - - - CAAX protease self-immunity
HEBBHNLP_00095 8.3e-126 ynaD - - J - - - Acetyltransferase (GNAT) domain
HEBBHNLP_00096 1.06e-238 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HEBBHNLP_00098 5.2e-273 - - - H - - - N-terminal domain of galactosyltransferase
HEBBHNLP_00099 6.07e-248 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
HEBBHNLP_00100 8.24e-156 - - - H - - - Methionine biosynthesis protein MetW
HEBBHNLP_00101 1.17e-120 - - - M - - - Glycosyltransferase like family
HEBBHNLP_00105 6.13e-14 - - - - - - - -
HEBBHNLP_00106 5.86e-38 - - - - - - - -
HEBBHNLP_00107 5.33e-118 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HEBBHNLP_00111 8.54e-212 - - - S - - - Calcineurin-like phosphoesterase
HEBBHNLP_00112 1.3e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
HEBBHNLP_00116 1.61e-09 - - - L - - - Transposase
HEBBHNLP_00117 1.25e-51 - - - S - - - Helix-turn-helix domain of transposase family ISL3
HEBBHNLP_00119 7.12e-38 - 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HEBBHNLP_00120 3.87e-201 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HEBBHNLP_00125 2.93e-18 - - - - - - - -
HEBBHNLP_00127 1.17e-94 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
HEBBHNLP_00129 2.55e-46 - - - O - - - Glutaredoxin
HEBBHNLP_00130 3.6e-237 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEBBHNLP_00132 2.33e-208 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEBBHNLP_00133 8.27e-48 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEBBHNLP_00134 2.76e-155 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEBBHNLP_00135 8.94e-82 - - - S - - - NrdI Flavodoxin like
HEBBHNLP_00141 2.52e-26 - - - S - - - Calcineurin-like phosphoesterase
HEBBHNLP_00150 4.53e-122 yorS - - S - - - 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
HEBBHNLP_00151 7.86e-106 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
HEBBHNLP_00156 8.19e-132 - - - S - - - protein conserved in bacteria
HEBBHNLP_00157 0.0 - 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HEBBHNLP_00158 2.74e-81 - 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HEBBHNLP_00159 0.0 - - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HEBBHNLP_00160 3.31e-286 - - - L - - - DNA primase activity
HEBBHNLP_00161 0.0 - - - J - - - DnaB-like helicase C terminal domain
HEBBHNLP_00162 1.45e-108 - - - - - - - -
HEBBHNLP_00163 5.21e-228 - - - L - - - AAA domain
HEBBHNLP_00164 2.56e-198 - - - - - - - -
HEBBHNLP_00169 5.54e-107 - - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HEBBHNLP_00170 4.35e-65 - - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HEBBHNLP_00172 2.22e-159 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
HEBBHNLP_00173 3.32e-120 - - - S - - - DNA ligase (ATP) activity
HEBBHNLP_00175 1.01e-79 - - - - - - - -
HEBBHNLP_00178 6.53e-70 - - - - - - - -
HEBBHNLP_00181 6.74e-52 - - - - - - - -
HEBBHNLP_00183 5.11e-115 - - - S - - - Protein of unknown function (DUF1273)
HEBBHNLP_00193 4.78e-46 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HEBBHNLP_00194 1.37e-224 - - - - - - - -
HEBBHNLP_00195 0.0 - - - S - - - DNA-sulfur modification-associated
HEBBHNLP_00196 6.84e-253 - - - L - - - Belongs to the 'phage' integrase family
HEBBHNLP_00201 9.24e-165 - - - - - - - -
HEBBHNLP_00203 1.23e-43 yoaF - - - - - - -
HEBBHNLP_00205 1.97e-101 - - - S - - - MepB protein
HEBBHNLP_00213 2.77e-41 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HEBBHNLP_00214 2.37e-104 yoaW - - - - - - -
HEBBHNLP_00215 2.46e-10 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HEBBHNLP_00216 6.01e-96 - - - - - - - -
HEBBHNLP_00219 2.93e-53 - - - S - - - Psort location Cytoplasmic, score
HEBBHNLP_00222 3.5e-259 - - - - - - - -
HEBBHNLP_00223 1.71e-122 - - - - - - - -
HEBBHNLP_00226 1.44e-40 bldD - - K ko:K07110,ko:K21572 - ko00000,ko02000,ko03000 domain, Protein
HEBBHNLP_00228 0.0 - - - - - - - -
HEBBHNLP_00229 2.88e-46 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HEBBHNLP_00230 3.48e-96 - - - - - - - -
HEBBHNLP_00233 8.61e-272 - - - S - - - Calcineurin-like phosphoesterase superfamily domain
HEBBHNLP_00236 1.55e-130 - - - - - - - -
HEBBHNLP_00240 1.65e-84 - - - - - - - -
HEBBHNLP_00243 3.77e-81 - - - - - - - -
HEBBHNLP_00244 3.33e-111 - - - - - - - -
HEBBHNLP_00245 2.8e-168 - - - - - - - -
HEBBHNLP_00246 3.8e-140 - - - - - - - -
HEBBHNLP_00249 2.05e-74 - - - - - - - -
HEBBHNLP_00250 1.55e-158 - - - - - - - -
HEBBHNLP_00253 3.4e-72 - - - - - - - -
HEBBHNLP_00254 4.49e-86 - - - - - - - -
HEBBHNLP_00255 7.88e-244 - - - A - - - Belongs to the 'phage' integrase family
HEBBHNLP_00257 4.51e-45 - - - - - - - -
HEBBHNLP_00258 0.0 - - - S - - - peptidoglycan catabolic process
HEBBHNLP_00259 4.01e-185 - - - S - - - Phage tail protein
HEBBHNLP_00260 0.0 - - - S - - - Pfam Transposase IS66
HEBBHNLP_00261 3.03e-192 - - - - - - - -
HEBBHNLP_00262 0.0 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
HEBBHNLP_00263 2.29e-237 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 Ami_2
HEBBHNLP_00265 1.97e-49 - - - S - - - Bacteriophage holin
HEBBHNLP_00266 2.08e-265 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HEBBHNLP_00268 7.71e-295 - - - S - - - damaged DNA binding
HEBBHNLP_00269 2.58e-71 - - - S - - - YolD-like protein
HEBBHNLP_00270 1.93e-53 - - - - - - - -
HEBBHNLP_00273 5.06e-126 - - - J - - - Acetyltransferase (GNAT) domain
HEBBHNLP_00274 1.46e-121 yokK - - S - - - SMI1 / KNR4 family
HEBBHNLP_00275 2.62e-100 - - - S - - - SMI1-KNR4 cell-wall
HEBBHNLP_00276 7.99e-73 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
HEBBHNLP_00277 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HEBBHNLP_00278 4.8e-83 - - - G - - - SMI1-KNR4 cell-wall
HEBBHNLP_00279 2.72e-75 - - - - - - - -
HEBBHNLP_00280 5.45e-47 - - - - - - - -
HEBBHNLP_00281 1.85e-164 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
HEBBHNLP_00282 1.12e-104 - - - S ko:K03824 - ko00000,ko01000 family acetyltransferase
HEBBHNLP_00283 1.04e-195 - - - L - - - Belongs to the 'phage' integrase family
HEBBHNLP_00284 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HEBBHNLP_00285 4.05e-89 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
HEBBHNLP_00286 2.77e-309 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HEBBHNLP_00287 1.82e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HEBBHNLP_00288 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
HEBBHNLP_00289 4.5e-147 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HEBBHNLP_00290 3.18e-141 - - - - - - - -
HEBBHNLP_00291 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEBBHNLP_00292 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEBBHNLP_00293 6.58e-88 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
HEBBHNLP_00294 1.2e-30 ymzA - - - - - - -
HEBBHNLP_00295 5.68e-32 - - - - - - - -
HEBBHNLP_00296 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HEBBHNLP_00297 6.54e-222 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HEBBHNLP_00298 5.41e-76 ymaF - - S - - - YmaF family
HEBBHNLP_00300 2.02e-66 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HEBBHNLP_00301 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
HEBBHNLP_00302 8.49e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
HEBBHNLP_00303 3.96e-163 ymaC - - S - - - Replication protein
HEBBHNLP_00305 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
HEBBHNLP_00306 2.67e-207 - - - S - - - Metallo-beta-lactamase superfamily
HEBBHNLP_00307 8.03e-81 ymzB - - - - - - -
HEBBHNLP_00308 1.02e-134 pksA - - K - - - Transcriptional regulator
HEBBHNLP_00309 5.61e-127 ymcC - - S - - - Membrane
HEBBHNLP_00310 3.04e-88 - - - S - - - Regulatory protein YrvL
HEBBHNLP_00312 9.14e-86 - - - S - - - Phage terminase, small subunit
HEBBHNLP_00313 5.05e-24 - - - - - - - -
HEBBHNLP_00314 3.74e-82 - - - S - - - HNH endonuclease
HEBBHNLP_00318 1.49e-19 - - - - - - - -
HEBBHNLP_00319 1.71e-77 - - - L - - - Phage integrase family
HEBBHNLP_00320 1.18e-27 - - - M - - - ArpU family transcriptional regulator
HEBBHNLP_00321 1.16e-18 - - - M - - - ArpU family transcriptional regulator
HEBBHNLP_00328 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HEBBHNLP_00329 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HEBBHNLP_00330 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
HEBBHNLP_00331 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
HEBBHNLP_00332 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HEBBHNLP_00333 1.97e-276 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HEBBHNLP_00334 8.31e-253 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HEBBHNLP_00335 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
HEBBHNLP_00336 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
HEBBHNLP_00337 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HEBBHNLP_00338 9.43e-279 pbpX - - V - - - Beta-lactamase
HEBBHNLP_00339 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HEBBHNLP_00340 2.15e-299 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HEBBHNLP_00341 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEBBHNLP_00342 3.05e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
HEBBHNLP_00343 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
HEBBHNLP_00344 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
HEBBHNLP_00345 6.33e-168 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HEBBHNLP_00346 9.66e-309 ymfH - - S - - - zinc protease
HEBBHNLP_00347 1.1e-297 albE - - S - - - Peptidase M16
HEBBHNLP_00348 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HEBBHNLP_00349 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
HEBBHNLP_00350 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HEBBHNLP_00351 1.42e-43 - - - S - - - YlzJ-like protein
HEBBHNLP_00352 1.68e-169 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
HEBBHNLP_00353 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEBBHNLP_00354 6.39e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEBBHNLP_00355 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HEBBHNLP_00356 2.36e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HEBBHNLP_00357 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HEBBHNLP_00358 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
HEBBHNLP_00359 1.53e-56 ymxH - - S - - - YlmC YmxH family
HEBBHNLP_00360 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
HEBBHNLP_00361 8.74e-234 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
HEBBHNLP_00362 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HEBBHNLP_00363 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HEBBHNLP_00364 3.15e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HEBBHNLP_00365 2.46e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HEBBHNLP_00366 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HEBBHNLP_00367 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
HEBBHNLP_00368 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HEBBHNLP_00369 6.16e-63 ylxQ - - J - - - ribosomal protein
HEBBHNLP_00370 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
HEBBHNLP_00371 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HEBBHNLP_00372 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HEBBHNLP_00373 2.24e-58 - - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 PFAM Lanthionine synthetase
HEBBHNLP_00374 5.12e-144 - - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC superfamily ATP binding cassette transporter, ABC
HEBBHNLP_00375 3.11e-158 bsaB - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
HEBBHNLP_00377 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEBBHNLP_00378 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HEBBHNLP_00379 4.72e-285 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HEBBHNLP_00380 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HEBBHNLP_00381 5.77e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HEBBHNLP_00382 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HEBBHNLP_00383 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HEBBHNLP_00384 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HEBBHNLP_00385 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HEBBHNLP_00386 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HEBBHNLP_00387 4e-100 ylxL - - - - - - -
HEBBHNLP_00388 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEBBHNLP_00389 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HEBBHNLP_00390 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HEBBHNLP_00391 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
HEBBHNLP_00392 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
HEBBHNLP_00393 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HEBBHNLP_00394 1.55e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
HEBBHNLP_00395 8.03e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
HEBBHNLP_00396 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HEBBHNLP_00397 3.89e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HEBBHNLP_00398 2.97e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
HEBBHNLP_00399 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
HEBBHNLP_00400 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
HEBBHNLP_00401 1.3e-135 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
HEBBHNLP_00402 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
HEBBHNLP_00403 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HEBBHNLP_00404 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HEBBHNLP_00405 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
HEBBHNLP_00406 1.66e-174 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
HEBBHNLP_00407 1.9e-94 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
HEBBHNLP_00408 1.93e-306 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
HEBBHNLP_00409 1.51e-78 ylxF - - S - - - MgtE intracellular N domain
HEBBHNLP_00410 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
HEBBHNLP_00411 3.5e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HEBBHNLP_00412 9.09e-143 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
HEBBHNLP_00413 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HEBBHNLP_00414 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
HEBBHNLP_00415 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
HEBBHNLP_00416 5.95e-96 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
HEBBHNLP_00417 6.6e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HEBBHNLP_00418 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HEBBHNLP_00419 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HEBBHNLP_00420 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HEBBHNLP_00421 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
HEBBHNLP_00422 2.22e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HEBBHNLP_00423 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEBBHNLP_00424 3.62e-215 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
HEBBHNLP_00425 3.09e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HEBBHNLP_00426 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HEBBHNLP_00427 9.86e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
HEBBHNLP_00428 0.0 ylqG - - - - - - -
HEBBHNLP_00429 8.29e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEBBHNLP_00430 5.7e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HEBBHNLP_00431 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HEBBHNLP_00432 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HEBBHNLP_00433 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HEBBHNLP_00434 1.97e-79 ylqD - - S - - - YlqD protein
HEBBHNLP_00435 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HEBBHNLP_00436 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HEBBHNLP_00437 1.96e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEBBHNLP_00438 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HEBBHNLP_00439 1.13e-112 - - - - - - - -
HEBBHNLP_00440 3.08e-58 orfX1 - - L - - - Transposase
HEBBHNLP_00441 2.28e-172 - - - L - - - Integrase core domain
HEBBHNLP_00442 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HEBBHNLP_00443 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HEBBHNLP_00444 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HEBBHNLP_00445 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEBBHNLP_00446 4.09e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HEBBHNLP_00447 3.09e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
HEBBHNLP_00448 2.39e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HEBBHNLP_00449 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HEBBHNLP_00450 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HEBBHNLP_00451 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
HEBBHNLP_00452 5.89e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
HEBBHNLP_00453 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
HEBBHNLP_00454 3.65e-78 yloU - - S - - - protein conserved in bacteria
HEBBHNLP_00455 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HEBBHNLP_00456 2.33e-156 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HEBBHNLP_00457 2.71e-152 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HEBBHNLP_00458 5.56e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HEBBHNLP_00459 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HEBBHNLP_00460 3.54e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HEBBHNLP_00461 2.16e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HEBBHNLP_00462 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HEBBHNLP_00463 1.01e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HEBBHNLP_00464 6.83e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEBBHNLP_00465 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEBBHNLP_00466 9.91e-284 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HEBBHNLP_00467 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HEBBHNLP_00468 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HEBBHNLP_00469 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
HEBBHNLP_00470 8.41e-202 yloC - - S - - - stress-induced protein
HEBBHNLP_00471 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
HEBBHNLP_00472 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
HEBBHNLP_00473 4.41e-106 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
HEBBHNLP_00474 1.76e-188 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
HEBBHNLP_00475 3.56e-186 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
HEBBHNLP_00476 1.59e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HEBBHNLP_00477 2.62e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
HEBBHNLP_00478 2.1e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
HEBBHNLP_00479 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
HEBBHNLP_00481 8.96e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEBBHNLP_00482 1.09e-162 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HEBBHNLP_00483 2.11e-221 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HEBBHNLP_00484 4.31e-182 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HEBBHNLP_00485 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
HEBBHNLP_00486 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HEBBHNLP_00487 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HEBBHNLP_00488 1.79e-214 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HEBBHNLP_00489 1.18e-292 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
HEBBHNLP_00490 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HEBBHNLP_00491 3.52e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HEBBHNLP_00492 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HEBBHNLP_00493 1.3e-82 ylyA - - T - - - COG1734 DnaK suppressor protein
HEBBHNLP_00494 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HEBBHNLP_00495 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
HEBBHNLP_00496 3.52e-177 ylmH - - S - - - conserved protein, contains S4-like domain
HEBBHNLP_00497 1.74e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
HEBBHNLP_00498 4.47e-87 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HEBBHNLP_00499 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HEBBHNLP_00500 1.07e-202 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
HEBBHNLP_00501 3.58e-51 ylmC - - S - - - sporulation protein
HEBBHNLP_00502 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
HEBBHNLP_00503 1.57e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HEBBHNLP_00504 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEBBHNLP_00505 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEBBHNLP_00506 5.86e-218 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HEBBHNLP_00507 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
HEBBHNLP_00508 2.14e-259 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HEBBHNLP_00509 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HEBBHNLP_00510 8.92e-75 sbp - - S - - - small basic protein
HEBBHNLP_00511 7.27e-124 ylxX - - S - - - protein conserved in bacteria
HEBBHNLP_00512 2.23e-142 ylxW - - S - - - protein conserved in bacteria
HEBBHNLP_00513 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HEBBHNLP_00514 1.52e-210 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
HEBBHNLP_00515 1.82e-255 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HEBBHNLP_00516 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HEBBHNLP_00517 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HEBBHNLP_00518 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HEBBHNLP_00519 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HEBBHNLP_00520 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
HEBBHNLP_00521 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HEBBHNLP_00522 3.42e-68 ftsL - - D - - - Essential cell division protein
HEBBHNLP_00523 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HEBBHNLP_00524 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HEBBHNLP_00525 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HEBBHNLP_00526 1.66e-216 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEBBHNLP_00527 3.26e-116 ylbP - - K - - - n-acetyltransferase
HEBBHNLP_00528 4.72e-107 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HEBBHNLP_00529 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HEBBHNLP_00530 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
HEBBHNLP_00532 1.43e-292 ylbM - - S - - - Belongs to the UPF0348 family
HEBBHNLP_00533 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HEBBHNLP_00534 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HEBBHNLP_00535 2.73e-282 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
HEBBHNLP_00536 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HEBBHNLP_00537 2.47e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
HEBBHNLP_00538 4.36e-52 ylbG - - S - - - UPF0298 protein
HEBBHNLP_00539 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
HEBBHNLP_00540 1.73e-48 ylbE - - S - - - YlbE-like protein
HEBBHNLP_00541 9.28e-89 ylbD - - S - - - Putative coat protein
HEBBHNLP_00542 3.61e-255 ylbC - - S - - - protein with SCP PR1 domains
HEBBHNLP_00543 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
HEBBHNLP_00544 1.61e-81 ylbA - - S - - - YugN-like family
HEBBHNLP_00545 1.48e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
HEBBHNLP_00546 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HEBBHNLP_00547 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HEBBHNLP_00548 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HEBBHNLP_00549 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HEBBHNLP_00550 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HEBBHNLP_00551 2.85e-212 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HEBBHNLP_00552 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HEBBHNLP_00553 7.05e-271 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HEBBHNLP_00554 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
HEBBHNLP_00555 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HEBBHNLP_00556 1.09e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HEBBHNLP_00557 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
HEBBHNLP_00558 9.93e-126 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEBBHNLP_00559 3.64e-43 ylaI - - S - - - protein conserved in bacteria
HEBBHNLP_00560 8.88e-63 ylaH - - S - - - YlaH-like protein
HEBBHNLP_00561 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HEBBHNLP_00562 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
HEBBHNLP_00563 5.7e-56 ylaE - - - - - - -
HEBBHNLP_00565 1.19e-86 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEBBHNLP_00566 1.44e-56 ylaB - - - - - - -
HEBBHNLP_00567 0.0 ylaA - - - - - - -
HEBBHNLP_00568 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
HEBBHNLP_00569 1.01e-220 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HEBBHNLP_00570 4.07e-98 ykzC - - S - - - Acetyltransferase (GNAT) family
HEBBHNLP_00571 1.51e-191 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
HEBBHNLP_00572 4.48e-35 ykzI - - - - - - -
HEBBHNLP_00573 2.15e-151 yktB - - S - - - Belongs to the UPF0637 family
HEBBHNLP_00574 6.37e-55 yktA - - S - - - Belongs to the UPF0223 family
HEBBHNLP_00575 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
HEBBHNLP_00576 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
HEBBHNLP_00577 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEBBHNLP_00578 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEBBHNLP_00579 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEBBHNLP_00580 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEBBHNLP_00581 1.06e-138 ykyA - - L - - - Putative cell-wall binding lipoprotein
HEBBHNLP_00582 1.26e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HEBBHNLP_00583 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEBBHNLP_00584 1.18e-186 ykrA - - S - - - hydrolases of the HAD superfamily
HEBBHNLP_00585 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
HEBBHNLP_00586 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEBBHNLP_00587 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HEBBHNLP_00588 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
HEBBHNLP_00589 3.42e-198 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
HEBBHNLP_00590 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HEBBHNLP_00591 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
HEBBHNLP_00592 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
HEBBHNLP_00593 1.09e-18 - - - S - - - Uncharacterized protein YkpC
HEBBHNLP_00594 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
HEBBHNLP_00595 9.18e-212 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEBBHNLP_00596 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEBBHNLP_00597 5.43e-52 ykoA - - - - - - -
HEBBHNLP_00598 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HEBBHNLP_00599 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HEBBHNLP_00600 4.07e-215 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
HEBBHNLP_00601 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
HEBBHNLP_00602 2.73e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HEBBHNLP_00603 1.44e-158 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEBBHNLP_00604 6.69e-233 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEBBHNLP_00605 1.08e-149 yknW - - S - - - Yip1 domain
HEBBHNLP_00606 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HEBBHNLP_00607 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HEBBHNLP_00608 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HEBBHNLP_00609 3.83e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
HEBBHNLP_00610 5.71e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
HEBBHNLP_00611 3.38e-310 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
HEBBHNLP_00612 6.24e-244 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HEBBHNLP_00613 7.57e-141 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HEBBHNLP_00614 2.33e-198 yknT - - - ko:K06437 - ko00000 -
HEBBHNLP_00615 1.78e-120 rok - - K - - - Repressor of ComK
HEBBHNLP_00616 2.45e-103 ykuV - - CO - - - thiol-disulfide
HEBBHNLP_00617 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
HEBBHNLP_00618 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
HEBBHNLP_00619 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
HEBBHNLP_00620 4.43e-273 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HEBBHNLP_00621 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HEBBHNLP_00622 1.03e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
HEBBHNLP_00623 7.09e-222 ykuO - - - - - - -
HEBBHNLP_00624 1.23e-110 - - - C ko:K03839 - ko00000 Flavodoxin domain
HEBBHNLP_00625 6.52e-216 ccpC - - K - - - Transcriptional regulator
HEBBHNLP_00626 5.15e-100 ykuL - - S - - - CBS domain
HEBBHNLP_00627 7.83e-38 ykzF - - S - - - Antirepressor AbbA
HEBBHNLP_00628 2.62e-121 - - - S ko:K09776 - ko00000 Ribonuclease H-like
HEBBHNLP_00629 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
HEBBHNLP_00631 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
HEBBHNLP_00632 2.6e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBBHNLP_00633 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
HEBBHNLP_00634 5.84e-115 ykuD - - S - - - protein conserved in bacteria
HEBBHNLP_00635 2.55e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HEBBHNLP_00636 3.71e-110 ykyB - - S - - - YkyB-like protein
HEBBHNLP_00637 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
HEBBHNLP_00638 1.05e-22 - - - - - - - -
HEBBHNLP_00639 3.59e-284 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HEBBHNLP_00640 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEBBHNLP_00641 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HEBBHNLP_00642 4.4e-171 ykwD - - J - - - protein with SCP PR1 domains
HEBBHNLP_00643 4.39e-17 vgb - - H ko:K18235 - ko00000,ko01000,ko01504 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
HEBBHNLP_00644 4.02e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HEBBHNLP_00645 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HEBBHNLP_00646 4.37e-162 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEBBHNLP_00647 2.49e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
HEBBHNLP_00648 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
HEBBHNLP_00649 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEBBHNLP_00650 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
HEBBHNLP_00651 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEBBHNLP_00652 2.79e-167 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
HEBBHNLP_00653 8.63e-226 ykvZ - - K - - - Transcriptional regulator
HEBBHNLP_00655 7.84e-264 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
HEBBHNLP_00656 3.99e-09 - - - - - - - -
HEBBHNLP_00657 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
HEBBHNLP_00658 1.6e-114 stoA - - CO - - - thiol-disulfide
HEBBHNLP_00659 6.46e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEBBHNLP_00660 5.26e-141 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
HEBBHNLP_00661 1.51e-38 - - - - - - - -
HEBBHNLP_00662 5.43e-35 ykvS - - S - - - protein conserved in bacteria
HEBBHNLP_00663 6.3e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
HEBBHNLP_00664 1.65e-15 - - - L - - - Phage integrase family
HEBBHNLP_00665 2.2e-171 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HEBBHNLP_00666 9.79e-80 ykvN - - K - - - Transcriptional regulator
HEBBHNLP_00667 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HEBBHNLP_00668 3.56e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HEBBHNLP_00669 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
HEBBHNLP_00670 2.61e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HEBBHNLP_00671 8.23e-228 ykvI - - S - - - membrane
HEBBHNLP_00672 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
HEBBHNLP_00673 1.65e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
HEBBHNLP_00674 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
HEBBHNLP_00675 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
HEBBHNLP_00676 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HEBBHNLP_00677 1.18e-94 eag - - - - - - -
HEBBHNLP_00679 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
HEBBHNLP_00680 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HEBBHNLP_00681 1.84e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HEBBHNLP_00682 1.77e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HEBBHNLP_00683 9.72e-295 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HEBBHNLP_00684 4.81e-296 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HEBBHNLP_00685 3.31e-192 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HEBBHNLP_00686 2.76e-290 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HEBBHNLP_00687 1.33e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HEBBHNLP_00689 7.91e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEBBHNLP_00690 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEBBHNLP_00691 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
HEBBHNLP_00692 1.77e-28 ykzE - - - - - - -
HEBBHNLP_00694 5.1e-301 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
HEBBHNLP_00695 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HEBBHNLP_00696 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
HEBBHNLP_00697 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
HEBBHNLP_00698 6.63e-191 rsgI - - S - - - Anti-sigma factor N-terminus
HEBBHNLP_00699 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEBBHNLP_00700 4.63e-227 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HEBBHNLP_00701 6.94e-143 ykoX - - S - - - membrane-associated protein
HEBBHNLP_00702 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
HEBBHNLP_00703 1.25e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HEBBHNLP_00704 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
HEBBHNLP_00705 9.49e-238 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
HEBBHNLP_00706 0.0 ykoS - - - - - - -
HEBBHNLP_00707 1.77e-197 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HEBBHNLP_00708 2.79e-126 ykoP - - G - - - polysaccharide deacetylase
HEBBHNLP_00709 1.58e-270 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HEBBHNLP_00710 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
HEBBHNLP_00711 3.04e-36 ykoL - - - - - - -
HEBBHNLP_00712 1.63e-25 - - - - - - - -
HEBBHNLP_00713 1.49e-70 tnrA - - K - - - transcriptional
HEBBHNLP_00714 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
HEBBHNLP_00716 1.45e-08 - - - - - - - -
HEBBHNLP_00717 7.2e-109 ykoJ - - S - - - Peptidase propeptide and YPEB domain
HEBBHNLP_00718 1.31e-143 ykoI - - S - - - Peptidase propeptide and YPEB domain
HEBBHNLP_00719 6.32e-309 ykoH - - T - - - Histidine kinase
HEBBHNLP_00720 5.23e-160 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBBHNLP_00721 2.44e-142 ykoF - - S - - - YKOF-related Family
HEBBHNLP_00722 3.99e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HEBBHNLP_00723 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEBBHNLP_00724 2.57e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HEBBHNLP_00725 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEBBHNLP_00726 3.66e-226 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HEBBHNLP_00727 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HEBBHNLP_00728 1.34e-113 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
HEBBHNLP_00729 2.34e-93 ohrB - - O - - - Organic hydroperoxide resistance protein
HEBBHNLP_00730 1.42e-97 ohrR - - K - - - COG1846 Transcriptional regulators
HEBBHNLP_00731 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
HEBBHNLP_00732 5.98e-285 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HEBBHNLP_00733 4.3e-255 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEBBHNLP_00734 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HEBBHNLP_00735 2.75e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
HEBBHNLP_00736 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
HEBBHNLP_00737 2.43e-126 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HEBBHNLP_00738 6.42e-128 ykkA - - S - - - Protein of unknown function (DUF664)
HEBBHNLP_00739 3.95e-167 ykjA - - S - - - Protein of unknown function (DUF421)
HEBBHNLP_00740 2.11e-16 - - - - - - - -
HEBBHNLP_00741 5.35e-289 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HEBBHNLP_00742 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
HEBBHNLP_00743 2.53e-205 ykgA - - E - - - Amidinotransferase
HEBBHNLP_00744 4.67e-260 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
HEBBHNLP_00745 8.44e-237 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEBBHNLP_00746 6.68e-206 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HEBBHNLP_00747 4.64e-255 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HEBBHNLP_00748 3.75e-222 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
HEBBHNLP_00750 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HEBBHNLP_00751 2.23e-235 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEBBHNLP_00752 3.02e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEBBHNLP_00753 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEBBHNLP_00754 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
HEBBHNLP_00755 8.77e-174 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
HEBBHNLP_00756 4.87e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEBBHNLP_00758 2.21e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HEBBHNLP_00759 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEBBHNLP_00760 2.82e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HEBBHNLP_00761 3e-308 steT - - E ko:K03294 - ko00000 amino acid
HEBBHNLP_00762 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
HEBBHNLP_00763 6.01e-223 pit - - P ko:K03306 - ko00000 phosphate transporter
HEBBHNLP_00764 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
HEBBHNLP_00765 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
HEBBHNLP_00767 3.73e-208 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
HEBBHNLP_00768 8.12e-53 xhlB - - S - - - SPP1 phage holin
HEBBHNLP_00769 9.39e-38 xhlA - - S - - - Haemolysin XhlA
HEBBHNLP_00770 2.42e-15 xkdX - - - - - - -
HEBBHNLP_00772 2.97e-130 - - - - - - - -
HEBBHNLP_00773 4.43e-56 - - - - - - - -
HEBBHNLP_00774 3.92e-135 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
HEBBHNLP_00775 1.64e-239 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HEBBHNLP_00776 9.01e-89 xkdS - - S - - - Protein of unknown function (DUF2634)
HEBBHNLP_00777 5.05e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
HEBBHNLP_00778 4.47e-230 xkdQ - - G - - - NLP P60 protein
HEBBHNLP_00779 4e-155 xkdP - - S - - - Lysin motif
HEBBHNLP_00780 0.0 xkdO - - L - - - Transglycosylase SLT domain
HEBBHNLP_00781 3.34e-101 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
HEBBHNLP_00782 6.01e-99 xkdM - - S - - - Phage tail tube protein
HEBBHNLP_00783 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
HEBBHNLP_00784 2.87e-101 xkdJ - - - - - - -
HEBBHNLP_00785 2.38e-114 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
HEBBHNLP_00786 1.44e-83 yqbH - - S - - - Domain of unknown function (DUF3599)
HEBBHNLP_00787 1.63e-82 yqbG - - S - - - Protein of unknown function (DUF3199)
HEBBHNLP_00788 3.91e-217 xkdG - - S - - - Phage capsid family
HEBBHNLP_00789 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
HEBBHNLP_00790 0.0 yqbA - - S - - - portal protein
HEBBHNLP_00791 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
HEBBHNLP_00792 2.27e-177 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
HEBBHNLP_00793 3.31e-109 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HEBBHNLP_00797 3.55e-151 xkdC - - L - - - Bacterial dnaA protein
HEBBHNLP_00798 1.07e-202 xkdB - - K - - - sequence-specific DNA binding
HEBBHNLP_00800 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
HEBBHNLP_00801 1.79e-143 xkdA - - E - - - IrrE N-terminal-like domain
HEBBHNLP_00802 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
HEBBHNLP_00803 1.11e-138 yjqB - - S - - - Pfam:DUF867
HEBBHNLP_00804 2.24e-79 yjqA - - S - - - Bacterial PH domain
HEBBHNLP_00805 1.26e-216 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HEBBHNLP_00806 1.79e-55 - - - S - - - YCII-related domain
HEBBHNLP_00808 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HEBBHNLP_00809 1.01e-312 VCP - - O - - - AAA domain (dynein-related subfamily)
HEBBHNLP_00810 1.91e-103 yjoA - - S - - - DinB family
HEBBHNLP_00811 4.56e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
HEBBHNLP_00812 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
HEBBHNLP_00813 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
HEBBHNLP_00814 9.87e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
HEBBHNLP_00815 1.13e-288 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
HEBBHNLP_00816 1.83e-194 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBBHNLP_00817 1.12e-272 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
HEBBHNLP_00818 2.65e-245 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
HEBBHNLP_00819 5.72e-239 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
HEBBHNLP_00820 2.15e-314 - - - G ko:K03292 - ko00000 symporter YjmB
HEBBHNLP_00821 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
HEBBHNLP_00822 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HEBBHNLP_00823 5.65e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
HEBBHNLP_00824 1.17e-116 yjlB - - S - - - Cupin domain
HEBBHNLP_00825 1.81e-224 yjlA - - EG - - - Putative multidrug resistance efflux transporter
HEBBHNLP_00826 1.81e-171 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HEBBHNLP_00827 2.59e-155 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
HEBBHNLP_00828 1.68e-186 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
HEBBHNLP_00829 3.2e-41 - - - - - - - -
HEBBHNLP_00830 1.76e-279 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HEBBHNLP_00831 4.35e-282 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HEBBHNLP_00833 2.4e-143 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HEBBHNLP_00835 9.24e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
HEBBHNLP_00836 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
HEBBHNLP_00837 4.96e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
HEBBHNLP_00838 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
HEBBHNLP_00839 6.01e-215 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
HEBBHNLP_00840 2.68e-28 yjfB - - S - - - Putative motility protein
HEBBHNLP_00841 8.68e-106 - - - S - - - Protein of unknown function (DUF2690)
HEBBHNLP_00842 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
HEBBHNLP_00844 2.52e-222 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HEBBHNLP_00845 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
HEBBHNLP_00846 3.95e-22 - - - S - - - Domain of unknown function (DUF4177)
HEBBHNLP_00847 3.92e-102 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEBBHNLP_00849 3.61e-117 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HEBBHNLP_00850 3.59e-73 yjdF3 - - S - - - Protein of unknown function (DUF2992)
HEBBHNLP_00851 1.99e-237 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HEBBHNLP_00852 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEBBHNLP_00853 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
HEBBHNLP_00854 5.1e-60 yjcN - - - - - - -
HEBBHNLP_00855 1.81e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
HEBBHNLP_00856 1.14e-109 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HEBBHNLP_00857 1.08e-69 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HEBBHNLP_00861 5.27e-311 - - - M - - - nucleic acid phosphodiester bond hydrolysis
HEBBHNLP_00862 9.36e-41 - - - - - - - -
HEBBHNLP_00863 6.25e-24 - - - - - - - -
HEBBHNLP_00865 1.05e-273 yjcL - - S - - - Protein of unknown function (DUF819)
HEBBHNLP_00866 7.44e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
HEBBHNLP_00867 2.61e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HEBBHNLP_00868 1.14e-272 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HEBBHNLP_00869 6.65e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
HEBBHNLP_00870 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
HEBBHNLP_00871 7.75e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEBBHNLP_00872 6.31e-51 - - - - - - - -
HEBBHNLP_00873 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HEBBHNLP_00874 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
HEBBHNLP_00877 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
HEBBHNLP_00878 4.12e-72 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
HEBBHNLP_00879 1.06e-34 cotW - - - ko:K06341 - ko00000 -
HEBBHNLP_00880 2.87e-94 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
HEBBHNLP_00881 3.12e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
HEBBHNLP_00882 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
HEBBHNLP_00883 1.63e-100 yjbX - - S - - - Spore coat protein
HEBBHNLP_00884 3.54e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HEBBHNLP_00885 2.8e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HEBBHNLP_00886 1.77e-237 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HEBBHNLP_00887 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HEBBHNLP_00888 2.18e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
HEBBHNLP_00889 2.46e-272 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
HEBBHNLP_00890 2.32e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
HEBBHNLP_00891 2.32e-176 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HEBBHNLP_00892 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HEBBHNLP_00893 3.3e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HEBBHNLP_00894 2.48e-201 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HEBBHNLP_00895 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEBBHNLP_00896 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
HEBBHNLP_00897 7.61e-81 yjbL - - S - - - Belongs to the UPF0738 family
HEBBHNLP_00898 7.02e-128 yjbK - - S - - - protein conserved in bacteria
HEBBHNLP_00899 4.85e-127 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HEBBHNLP_00900 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
HEBBHNLP_00901 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
HEBBHNLP_00902 2.68e-28 - - - - - - - -
HEBBHNLP_00903 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HEBBHNLP_00904 1.64e-277 coiA - - S ko:K06198 - ko00000 Competence protein
HEBBHNLP_00905 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HEBBHNLP_00906 2.37e-142 yjbE - - P - - - Integral membrane protein TerC family
HEBBHNLP_00907 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HEBBHNLP_00908 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEBBHNLP_00909 7.88e-259 yjbB - - EGP - - - Major Facilitator Superfamily
HEBBHNLP_00910 1.27e-219 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEBBHNLP_00911 1.12e-248 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEBBHNLP_00912 6.2e-211 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEBBHNLP_00913 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEBBHNLP_00914 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HEBBHNLP_00915 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
HEBBHNLP_00916 1.84e-189 yjbA - - S - - - Belongs to the UPF0736 family
HEBBHNLP_00917 1.48e-197 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEBBHNLP_00918 6.73e-216 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEBBHNLP_00919 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
HEBBHNLP_00920 4.88e-236 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEBBHNLP_00921 3.56e-233 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEBBHNLP_00922 2.14e-189 yjaZ - - O - - - Zn-dependent protease
HEBBHNLP_00923 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEBBHNLP_00924 2.28e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEBBHNLP_00925 3.48e-33 yjzB - - - - - - -
HEBBHNLP_00926 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
HEBBHNLP_00927 4.32e-233 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
HEBBHNLP_00928 3.52e-130 yjaV - - - - - - -
HEBBHNLP_00929 2.42e-182 yjaU - - I - - - carboxylic ester hydrolase activity
HEBBHNLP_00930 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
HEBBHNLP_00931 2.51e-39 yjzC - - S - - - YjzC-like protein
HEBBHNLP_00932 1.05e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HEBBHNLP_00933 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
HEBBHNLP_00934 6.67e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HEBBHNLP_00935 2.3e-276 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
HEBBHNLP_00936 1.27e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HEBBHNLP_00937 3.37e-291 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HEBBHNLP_00938 1.18e-251 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HEBBHNLP_00939 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
HEBBHNLP_00940 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
HEBBHNLP_00941 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
HEBBHNLP_00942 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
HEBBHNLP_00943 1.02e-184 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HEBBHNLP_00944 2.16e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HEBBHNLP_00945 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
HEBBHNLP_00946 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
HEBBHNLP_00947 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HEBBHNLP_00948 7.19e-199 yitS - - S - - - protein conserved in bacteria
HEBBHNLP_00949 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
HEBBHNLP_00950 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
HEBBHNLP_00951 5.86e-118 - - - - - - - -
HEBBHNLP_00952 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
HEBBHNLP_00953 5.46e-126 - - - S - - - Sporulation delaying protein SdpA
HEBBHNLP_00954 1.94e-216 - - - - - - - -
HEBBHNLP_00955 4.16e-122 - - - - - - - -
HEBBHNLP_00956 2.26e-203 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
HEBBHNLP_00957 2.48e-76 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
HEBBHNLP_00958 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HEBBHNLP_00959 2.16e-93 - - - S - - - Acetyltransferase (GNAT) domain
HEBBHNLP_00960 4.49e-197 yitH - - K - - - Acetyltransferase (GNAT) domain
HEBBHNLP_00961 8.28e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HEBBHNLP_00962 2.91e-281 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HEBBHNLP_00963 6.62e-140 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEBBHNLP_00964 7.15e-179 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
HEBBHNLP_00965 5.62e-155 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
HEBBHNLP_00966 4.35e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
HEBBHNLP_00967 7.62e-293 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
HEBBHNLP_00968 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HEBBHNLP_00969 1.85e-198 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HEBBHNLP_00970 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
HEBBHNLP_00971 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEBBHNLP_00972 1.6e-132 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
HEBBHNLP_00973 6.72e-118 yisT - - S - - - DinB family
HEBBHNLP_00974 1.36e-244 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HEBBHNLP_00975 4.32e-234 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HEBBHNLP_00976 2.85e-207 yisR - - K - - - Transcriptional regulator
HEBBHNLP_00977 2.91e-310 yisQ - - V - - - Mate efflux family protein
HEBBHNLP_00978 8.91e-189 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
HEBBHNLP_00979 1.07e-114 yizA - - S - - - Damage-inducible protein DinB
HEBBHNLP_00980 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HEBBHNLP_00981 8.67e-131 yisN - - S - - - Protein of unknown function (DUF2777)
HEBBHNLP_00982 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HEBBHNLP_00983 1.02e-74 yisL - - S - - - UPF0344 protein
HEBBHNLP_00984 7.64e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HEBBHNLP_00985 2.46e-218 cotH - - M ko:K06330 - ko00000 Spore Coat
HEBBHNLP_00986 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
HEBBHNLP_00987 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
HEBBHNLP_00988 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
HEBBHNLP_00989 3.34e-92 gerPC - - S ko:K06301 - ko00000 Spore germination protein
HEBBHNLP_00990 1.49e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
HEBBHNLP_00991 3.92e-86 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
HEBBHNLP_00992 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
HEBBHNLP_00993 6.4e-65 yisB - - V - - - COG1403 Restriction endonuclease
HEBBHNLP_00994 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
HEBBHNLP_00995 1.1e-277 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HEBBHNLP_00996 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HEBBHNLP_00997 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
HEBBHNLP_00998 9.3e-102 yhjR - - S - - - Rubrerythrin
HEBBHNLP_00999 3.54e-77 yhjQ - - C - - - COG1145 Ferredoxin
HEBBHNLP_01000 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
HEBBHNLP_01001 2.35e-268 - - - EGP - - - Transmembrane secretion effector
HEBBHNLP_01002 8.35e-258 yhjN - - S ko:K07120 - ko00000 membrane
HEBBHNLP_01003 4.36e-239 yhjM - - K - - - Transcriptional regulator
HEBBHNLP_01004 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
HEBBHNLP_01005 3.07e-204 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
HEBBHNLP_01006 6.61e-256 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HEBBHNLP_01007 8.57e-271 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
HEBBHNLP_01010 1.83e-118 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEBBHNLP_01011 0.0 yhjG - - CH - - - FAD binding domain
HEBBHNLP_01012 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HEBBHNLP_01013 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
HEBBHNLP_01014 4.13e-78 yhjD - - - - - - -
HEBBHNLP_01015 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
HEBBHNLP_01016 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEBBHNLP_01017 1.38e-54 yhjA - - S - - - Excalibur calcium-binding domain
HEBBHNLP_01018 7.32e-216 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HEBBHNLP_01019 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
HEBBHNLP_01020 9.84e-45 yhzC - - S - - - IDEAL
HEBBHNLP_01021 6.43e-203 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBBHNLP_01022 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
HEBBHNLP_01023 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
HEBBHNLP_01024 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HEBBHNLP_01025 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
HEBBHNLP_01026 1.22e-249 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HEBBHNLP_01027 2.27e-139 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
HEBBHNLP_01028 9.26e-222 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HEBBHNLP_01029 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
HEBBHNLP_01030 1.26e-101 - - - K - - - acetyltransferase
HEBBHNLP_01031 1.7e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HEBBHNLP_01032 1.11e-298 yhfN - - O - - - Peptidase M48
HEBBHNLP_01033 1.61e-84 yhfM - - - - - - -
HEBBHNLP_01034 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
HEBBHNLP_01035 6.1e-143 yhfK - - GM - - - NmrA-like family
HEBBHNLP_01036 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HEBBHNLP_01037 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HEBBHNLP_01038 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEBBHNLP_01039 1.79e-92 - - - S - - - ASCH
HEBBHNLP_01040 6.31e-252 yhfE - - G - - - peptidase M42
HEBBHNLP_01041 2.67e-177 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
HEBBHNLP_01042 1.77e-236 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEBBHNLP_01043 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
HEBBHNLP_01044 5.79e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
HEBBHNLP_01045 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HEBBHNLP_01046 1.33e-228 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HEBBHNLP_01047 2.14e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HEBBHNLP_01048 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HEBBHNLP_01049 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HEBBHNLP_01050 4.07e-44 - - - C - - - Rubrerythrin
HEBBHNLP_01051 1.9e-312 yhfA - - C - - - membrane
HEBBHNLP_01052 3.11e-291 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HEBBHNLP_01053 3.94e-159 ecsC - - S - - - EcsC protein family
HEBBHNLP_01054 1.27e-271 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HEBBHNLP_01055 6.35e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
HEBBHNLP_01056 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HEBBHNLP_01057 2.51e-260 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HEBBHNLP_01058 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
HEBBHNLP_01059 9.66e-30 - - - - - - - -
HEBBHNLP_01060 3.89e-54 yhaH - - S - - - YtxH-like protein
HEBBHNLP_01061 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
HEBBHNLP_01062 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
HEBBHNLP_01063 1.4e-116 yhaK - - S - - - Putative zincin peptidase
HEBBHNLP_01064 2.33e-161 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HEBBHNLP_01065 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
HEBBHNLP_01066 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
HEBBHNLP_01067 0.0 yhaN - - L - - - AAA domain
HEBBHNLP_01068 9.44e-301 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
HEBBHNLP_01069 2.97e-271 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
HEBBHNLP_01070 2.27e-214 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEBBHNLP_01071 2.29e-36 - - - S - - - YhzD-like protein
HEBBHNLP_01072 8.52e-168 yhaR - - I - - - enoyl-CoA hydratase
HEBBHNLP_01074 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
HEBBHNLP_01075 7.21e-265 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
HEBBHNLP_01076 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
HEBBHNLP_01077 3.04e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
HEBBHNLP_01078 9.11e-262 yhaZ - - L - - - DNA alkylation repair enzyme
HEBBHNLP_01079 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
HEBBHNLP_01080 2.93e-259 yheB - - S - - - Belongs to the UPF0754 family
HEBBHNLP_01081 1.32e-273 yheC - - HJ - - - YheC/D like ATP-grasp
HEBBHNLP_01082 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
HEBBHNLP_01083 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
HEBBHNLP_01084 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
HEBBHNLP_01085 5.05e-138 yheG - - GM - - - NAD(P)H-binding
HEBBHNLP_01086 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HEBBHNLP_01087 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HEBBHNLP_01088 3.16e-108 nhaX - - T - - - Belongs to the universal stress protein A family
HEBBHNLP_01089 3.61e-303 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
HEBBHNLP_01090 3.69e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HEBBHNLP_01091 3.54e-194 nodB1 - - G - - - deacetylase
HEBBHNLP_01092 1.98e-178 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HEBBHNLP_01093 9.73e-239 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
HEBBHNLP_01094 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
HEBBHNLP_01095 6.1e-171 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HEBBHNLP_01096 3.38e-86 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEBBHNLP_01097 1.01e-65 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEBBHNLP_01098 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
HEBBHNLP_01099 5.1e-284 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HEBBHNLP_01100 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
HEBBHNLP_01101 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HEBBHNLP_01102 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HEBBHNLP_01103 6.74e-244 yhdN - - C - - - Aldo keto reductase
HEBBHNLP_01104 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEBBHNLP_01105 1.24e-257 yhdL - - S - - - Sigma factor regulator N-terminal
HEBBHNLP_01106 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
HEBBHNLP_01107 7.13e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEBBHNLP_01108 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEBBHNLP_01109 1.43e-308 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HEBBHNLP_01110 4.2e-315 yhdG - - E ko:K03294 - ko00000 amino acid
HEBBHNLP_01111 5.51e-206 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBBHNLP_01112 5.28e-261 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HEBBHNLP_01113 8.17e-209 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
HEBBHNLP_01114 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HEBBHNLP_01115 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HEBBHNLP_01116 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
HEBBHNLP_01117 2.91e-304 ygxB - - M - - - Conserved TM helix
HEBBHNLP_01118 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
HEBBHNLP_01119 5.63e-274 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HEBBHNLP_01120 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
HEBBHNLP_01121 1.65e-51 yhdB - - S - - - YhdB-like protein
HEBBHNLP_01122 3.84e-115 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
HEBBHNLP_01123 7.73e-144 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEBBHNLP_01124 1.54e-271 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
HEBBHNLP_01125 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
HEBBHNLP_01126 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HEBBHNLP_01127 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEBBHNLP_01128 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HEBBHNLP_01129 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HEBBHNLP_01130 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEBBHNLP_01131 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HEBBHNLP_01132 2.5e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
HEBBHNLP_01133 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
HEBBHNLP_01134 2.03e-87 yhcU - - S - - - Family of unknown function (DUF5365)
HEBBHNLP_01135 4.78e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HEBBHNLP_01136 1.78e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
HEBBHNLP_01137 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HEBBHNLP_01138 1.68e-146 yhcQ - - M - - - Spore coat protein
HEBBHNLP_01139 4.43e-224 yhcP - - - - - - -
HEBBHNLP_01140 5.13e-103 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEBBHNLP_01141 4.43e-61 yhcM - - - - - - -
HEBBHNLP_01142 3.22e-65 - - - K - - - Transcriptional regulator PadR-like family
HEBBHNLP_01143 1.69e-114 - - - S - - - Protein of unknown function (DUF2812)
HEBBHNLP_01144 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEBBHNLP_01145 3.36e-249 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
HEBBHNLP_01146 3.54e-191 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HEBBHNLP_01147 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
HEBBHNLP_01148 9.87e-212 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HEBBHNLP_01149 1.25e-210 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEBBHNLP_01150 3.24e-156 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEBBHNLP_01151 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
HEBBHNLP_01152 8.31e-69 - - - - - - - -
HEBBHNLP_01153 5.28e-52 yhcC - - - - - - -
HEBBHNLP_01154 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
HEBBHNLP_01155 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
HEBBHNLP_01156 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
HEBBHNLP_01157 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
HEBBHNLP_01158 1.41e-285 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
HEBBHNLP_01159 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
HEBBHNLP_01160 9.07e-107 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
HEBBHNLP_01161 1.32e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
HEBBHNLP_01162 3.4e-143 yhbD - - K - - - Protein of unknown function (DUF4004)
HEBBHNLP_01163 1.61e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HEBBHNLP_01164 2.77e-225 yhbB - - S - - - Putative amidase domain
HEBBHNLP_01165 1.7e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HEBBHNLP_01166 6.43e-146 yhzB - - S - - - B3/4 domain
HEBBHNLP_01168 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
HEBBHNLP_01169 5.19e-98 ygaO - - - - - - -
HEBBHNLP_01170 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEBBHNLP_01172 2.2e-274 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
HEBBHNLP_01173 8.33e-190 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HEBBHNLP_01174 1.7e-217 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
HEBBHNLP_01175 9.01e-179 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HEBBHNLP_01176 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HEBBHNLP_01178 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HEBBHNLP_01179 2.24e-169 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
HEBBHNLP_01180 1.58e-36 - - - - - - - -
HEBBHNLP_01181 2.22e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
HEBBHNLP_01198 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HEBBHNLP_01199 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
HEBBHNLP_01200 3.38e-73 ygzB - - S - - - UPF0295 protein
HEBBHNLP_01201 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HEBBHNLP_01202 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
HEBBHNLP_01203 3.26e-312 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
HEBBHNLP_01204 1.87e-238 ygaE - - S - - - Membrane
HEBBHNLP_01205 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
HEBBHNLP_01206 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
HEBBHNLP_01207 8.19e-49 ygaB - - S - - - YgaB-like protein
HEBBHNLP_01208 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
HEBBHNLP_01209 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBBHNLP_01210 1.73e-48 yfhS - - - - - - -
HEBBHNLP_01211 1.31e-265 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
HEBBHNLP_01212 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
HEBBHNLP_01213 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HEBBHNLP_01214 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HEBBHNLP_01215 1.13e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
HEBBHNLP_01216 5.4e-67 yfhL - - S - - - SdpI/YhfL protein family
HEBBHNLP_01217 2.23e-113 yfhK - - T - - - Bacterial SH3 domain homologues
HEBBHNLP_01218 8.95e-60 yfhJ - - S - - - WVELL protein
HEBBHNLP_01219 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
HEBBHNLP_01220 3.47e-268 yfhI - - EGP - - - -transporter
HEBBHNLP_01222 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
HEBBHNLP_01223 3.25e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
HEBBHNLP_01224 8.92e-219 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
HEBBHNLP_01226 8.86e-35 yfhD - - S - - - YfhD-like protein
HEBBHNLP_01227 1.94e-136 yfhC - - C - - - nitroreductase
HEBBHNLP_01228 8.52e-212 yfhB - - S - - - PhzF family
HEBBHNLP_01229 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBBHNLP_01230 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBBHNLP_01231 3.83e-231 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HEBBHNLP_01232 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEBBHNLP_01233 2.11e-103 yfiV - - K - - - transcriptional
HEBBHNLP_01234 0.0 yfiU - - EGP - - - the major facilitator superfamily
HEBBHNLP_01235 2.7e-126 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
HEBBHNLP_01236 1.91e-266 yfiS - - EGP - - - Major facilitator superfamily
HEBBHNLP_01237 1.34e-137 yfiR - - K - - - Transcriptional regulator
HEBBHNLP_01238 1.04e-249 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HEBBHNLP_01239 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
HEBBHNLP_01240 1.89e-128 padR - - K - - - transcriptional
HEBBHNLP_01241 3.01e-256 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
HEBBHNLP_01242 3.92e-269 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HEBBHNLP_01243 5.33e-215 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HEBBHNLP_01244 8.27e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
HEBBHNLP_01245 4.15e-240 baeS - - T - - - Histidine kinase
HEBBHNLP_01246 2.97e-208 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
HEBBHNLP_01247 4.06e-84 yfiD3 - - S - - - DoxX
HEBBHNLP_01248 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HEBBHNLP_01249 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
HEBBHNLP_01250 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
HEBBHNLP_01251 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEBBHNLP_01252 5.03e-180 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
HEBBHNLP_01253 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HEBBHNLP_01254 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
HEBBHNLP_01255 5.56e-270 yfjB - - - - - - -
HEBBHNLP_01256 1.02e-184 yfjC - - - - - - -
HEBBHNLP_01257 3.52e-130 yfjD - - S - - - Family of unknown function (DUF5381)
HEBBHNLP_01258 2.26e-102 - - - S - - - Family of unknown function (DUF5381)
HEBBHNLP_01259 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
HEBBHNLP_01260 9.56e-35 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
HEBBHNLP_01261 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
HEBBHNLP_01262 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEBBHNLP_01263 6.35e-260 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEBBHNLP_01264 1.59e-243 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEBBHNLP_01265 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEBBHNLP_01267 3.74e-108 yfjM - - S - - - Psort location Cytoplasmic, score
HEBBHNLP_01268 4.72e-241 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEBBHNLP_01269 3.04e-59 - - - S - - - YfzA-like protein
HEBBHNLP_01270 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEBBHNLP_01271 2.76e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HEBBHNLP_01272 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
HEBBHNLP_01273 1.61e-192 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HEBBHNLP_01274 7.24e-198 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
HEBBHNLP_01275 3.26e-36 yfjT - - - - - - -
HEBBHNLP_01276 1.76e-283 yfkA - - S - - - YfkB-like domain
HEBBHNLP_01277 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
HEBBHNLP_01278 3.69e-189 yfkD - - S - - - YfkD-like protein
HEBBHNLP_01279 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
HEBBHNLP_01280 5.22e-276 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HEBBHNLP_01281 1.64e-12 - - - - - - - -
HEBBHNLP_01282 1.37e-183 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HEBBHNLP_01283 1.03e-66 yfkI - - S - - - gas vesicle protein
HEBBHNLP_01284 9.78e-107 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEBBHNLP_01285 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
HEBBHNLP_01286 5.1e-265 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HEBBHNLP_01287 1.11e-113 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
HEBBHNLP_01288 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HEBBHNLP_01289 6.16e-160 frp - - C - - - nitroreductase
HEBBHNLP_01290 5.05e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
HEBBHNLP_01291 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
HEBBHNLP_01292 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEBBHNLP_01293 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
HEBBHNLP_01294 9.28e-271 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
HEBBHNLP_01296 3.48e-246 yfkT - - E ko:K06309 - ko00000 Spore germination protein
HEBBHNLP_01297 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
HEBBHNLP_01298 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
HEBBHNLP_01299 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HEBBHNLP_01300 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HEBBHNLP_01301 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HEBBHNLP_01302 4.25e-65 yflH - - S - - - Protein of unknown function (DUF3243)
HEBBHNLP_01303 6.9e-27 yflI - - - - - - -
HEBBHNLP_01304 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
HEBBHNLP_01305 4.86e-157 yflK - - S - - - protein conserved in bacteria
HEBBHNLP_01306 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HEBBHNLP_01307 5.59e-275 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HEBBHNLP_01308 1.7e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HEBBHNLP_01309 1.53e-287 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HEBBHNLP_01310 1.82e-226 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
HEBBHNLP_01311 6.33e-96 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HEBBHNLP_01312 1.61e-40 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HEBBHNLP_01313 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HEBBHNLP_01314 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HEBBHNLP_01315 9.57e-305 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
HEBBHNLP_01316 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
HEBBHNLP_01317 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
HEBBHNLP_01318 6.5e-218 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HEBBHNLP_01319 8.17e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBBHNLP_01320 2.1e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBBHNLP_01321 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HEBBHNLP_01322 6.69e-239 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
HEBBHNLP_01323 2.66e-96 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
HEBBHNLP_01324 3.44e-262 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
HEBBHNLP_01325 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEBBHNLP_01326 5.23e-35 - - - - - - - -
HEBBHNLP_01327 3.59e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
HEBBHNLP_01328 1.44e-89 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
HEBBHNLP_01329 6.23e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
HEBBHNLP_01330 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEBBHNLP_01331 5.14e-161 yfmS - - NT - - - chemotaxis protein
HEBBHNLP_01332 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEBBHNLP_01333 1.97e-311 yfnA - - E ko:K03294 - ko00000 amino acid
HEBBHNLP_01334 6.12e-167 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HEBBHNLP_01335 7.24e-267 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HEBBHNLP_01336 6.7e-243 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
HEBBHNLP_01337 2.84e-285 yfnE - - S - - - Glycosyltransferase like family 2
HEBBHNLP_01338 1.82e-227 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
HEBBHNLP_01339 1.13e-218 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
HEBBHNLP_01340 9.83e-187 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
HEBBHNLP_01341 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HEBBHNLP_01342 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
HEBBHNLP_01343 1.26e-247 yetN - - S - - - Protein of unknown function (DUF3900)
HEBBHNLP_01345 1.29e-258 yetM - - CH - - - FAD binding domain
HEBBHNLP_01346 9.21e-115 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEBBHNLP_01347 2.55e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
HEBBHNLP_01348 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
HEBBHNLP_01349 2.17e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEBBHNLP_01350 5.4e-45 - - - - - - - -
HEBBHNLP_01351 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEBBHNLP_01352 6.64e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
HEBBHNLP_01353 1.81e-157 yetF - - S - - - membrane
HEBBHNLP_01354 8.24e-266 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HEBBHNLP_01355 8e-36 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HEBBHNLP_01356 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEBBHNLP_01357 6.84e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
HEBBHNLP_01358 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HEBBHNLP_01359 0.0 yetA - - - - - - -
HEBBHNLP_01360 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
HEBBHNLP_01361 8.77e-158 - - - E - - - GDSL-like Lipase/Acylhydrolase
HEBBHNLP_01362 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
HEBBHNLP_01363 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
HEBBHNLP_01364 1.99e-145 - - - S - - - Protein of unknown function, DUF624
HEBBHNLP_01365 9.51e-168 yesU - - S - - - Domain of unknown function (DUF1961)
HEBBHNLP_01366 8.39e-170 - - - E - - - GDSL-like Lipase/Acylhydrolase
HEBBHNLP_01367 0.0 yesS - - K - - - Transcriptional regulator
HEBBHNLP_01368 6.57e-253 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
HEBBHNLP_01369 8.48e-209 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEBBHNLP_01370 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEBBHNLP_01371 1.68e-313 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HEBBHNLP_01372 1.81e-253 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
HEBBHNLP_01373 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEBBHNLP_01374 4.8e-133 yesL - - S - - - Protein of unknown function, DUF624
HEBBHNLP_01376 3.99e-129 yesJ - - K - - - Acetyltransferase (GNAT) family
HEBBHNLP_01377 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
HEBBHNLP_01378 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
HEBBHNLP_01379 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
HEBBHNLP_01380 9.66e-193 yesF - - GM - - - NAD(P)H-binding
HEBBHNLP_01381 1.94e-104 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
HEBBHNLP_01382 2e-129 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
HEBBHNLP_01384 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
HEBBHNLP_01386 1.66e-269 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
HEBBHNLP_01387 1.23e-14 - - - S - - - Lysozyme inhibitor LprI
HEBBHNLP_01388 1.38e-206 - - - S - - - amine dehydrogenase activity
HEBBHNLP_01389 8.53e-128 - - - L - - - endonuclease activity
HEBBHNLP_01391 4.11e-116 - - - L - - - nucleic acid phosphodiester bond hydrolysis
HEBBHNLP_01392 7.87e-271 - - - L - - - nucleic acid phosphodiester bond hydrolysis
HEBBHNLP_01393 1.72e-71 - - - S - - - Protein of unknown function, DUF600
HEBBHNLP_01394 2.63e-47 - - - S - - - Protein of unknown function, DUF600
HEBBHNLP_01395 2.72e-06 - - - - - - - -
HEBBHNLP_01396 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEBBHNLP_01397 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HEBBHNLP_01398 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HEBBHNLP_01399 3.86e-186 yerO - - K - - - Transcriptional regulator
HEBBHNLP_01400 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEBBHNLP_01402 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEBBHNLP_01403 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEBBHNLP_01404 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
HEBBHNLP_01405 8.56e-251 yerI - - S - - - homoserine kinase type II (protein kinase fold)
HEBBHNLP_01406 1.02e-280 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
HEBBHNLP_01407 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HEBBHNLP_01408 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HEBBHNLP_01409 1.1e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HEBBHNLP_01411 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
HEBBHNLP_01412 7.62e-68 yerC - - S - - - protein conserved in bacteria
HEBBHNLP_01413 9.58e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
HEBBHNLP_01414 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
HEBBHNLP_01415 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
HEBBHNLP_01416 5.01e-293 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
HEBBHNLP_01417 1.06e-95 - - - K - - - helix_turn_helix ASNC type
HEBBHNLP_01418 1.63e-297 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HEBBHNLP_01419 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HEBBHNLP_01420 1.04e-136 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HEBBHNLP_01421 9.88e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HEBBHNLP_01422 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HEBBHNLP_01423 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEBBHNLP_01424 2.23e-165 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEBBHNLP_01425 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEBBHNLP_01426 4.12e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HEBBHNLP_01427 2.3e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HEBBHNLP_01428 1.82e-275 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HEBBHNLP_01429 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HEBBHNLP_01430 3.13e-38 yebG - - S - - - NETI protein
HEBBHNLP_01431 1.08e-119 yebE - - S - - - UPF0316 protein
HEBBHNLP_01433 5.85e-165 yebC - - M - - - Membrane
HEBBHNLP_01434 9.81e-283 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HEBBHNLP_01435 0.0 - - - S - - - Domain of unknown function (DUF4179)
HEBBHNLP_01436 1.33e-112 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEBBHNLP_01437 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HEBBHNLP_01438 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
HEBBHNLP_01439 7.86e-286 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HEBBHNLP_01440 5.62e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
HEBBHNLP_01441 1.76e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEBBHNLP_01442 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HEBBHNLP_01443 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
HEBBHNLP_01444 7.74e-61 yeaA - - S - - - Protein of unknown function (DUF4003)
HEBBHNLP_01445 2.95e-201 - - - I - - - Alpha/beta hydrolase family
HEBBHNLP_01446 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
HEBBHNLP_01448 1.2e-209 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
HEBBHNLP_01449 1.79e-84 ydjM - - M - - - Lytic transglycolase
HEBBHNLP_01450 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
HEBBHNLP_01451 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEBBHNLP_01452 1.37e-248 - - - S - - - Ion transport 2 domain protein
HEBBHNLP_01453 8.5e-202 ydjI - - S - - - virion core protein (lumpy skin disease virus)
HEBBHNLP_01454 4.44e-174 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
HEBBHNLP_01455 1.73e-226 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEBBHNLP_01456 6.25e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
HEBBHNLP_01457 3.64e-222 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
HEBBHNLP_01458 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
HEBBHNLP_01459 8.71e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HEBBHNLP_01460 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
HEBBHNLP_01461 4.7e-72 - - - L - - - Bacterial transcription activator, effector binding domain
HEBBHNLP_01462 1.14e-68 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
HEBBHNLP_01464 3.19e-112 - - - I ko:K15329 - ko00000,ko01008 Acyl transferase domain
HEBBHNLP_01465 1.06e-273 - - - L - - - pfam abc
HEBBHNLP_01466 4.03e-311 - - - Q ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 TIGRFAM amino acid adenylation domain
HEBBHNLP_01467 0.0 - - - Q ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 TIGRFAM amino acid adenylation domain
HEBBHNLP_01468 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
HEBBHNLP_01469 2.62e-258 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
HEBBHNLP_01470 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
HEBBHNLP_01471 3.1e-206 - - - V - - - ABC transporter transmembrane region
HEBBHNLP_01472 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HEBBHNLP_01473 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HEBBHNLP_01474 1.74e-166 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
HEBBHNLP_01475 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
HEBBHNLP_01476 8.73e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEBBHNLP_01477 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HEBBHNLP_01478 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HEBBHNLP_01479 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HEBBHNLP_01480 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
HEBBHNLP_01481 1.34e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HEBBHNLP_01482 4.91e-109 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HEBBHNLP_01483 2.8e-160 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
HEBBHNLP_01484 2.41e-111 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
HEBBHNLP_01485 2.38e-225 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HEBBHNLP_01488 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HEBBHNLP_01491 4.89e-202 ydhU - - P ko:K07217 - ko00000 Catalase
HEBBHNLP_01492 1.31e-268 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
HEBBHNLP_01493 5.09e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HEBBHNLP_01494 4.74e-212 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
HEBBHNLP_01495 7.75e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
HEBBHNLP_01496 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEBBHNLP_01497 3.09e-303 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEBBHNLP_01498 3.39e-67 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEBBHNLP_01499 1.88e-63 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEBBHNLP_01500 1.8e-254 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
HEBBHNLP_01501 1.4e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
HEBBHNLP_01502 3.43e-234 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HEBBHNLP_01503 1.27e-106 - - - K - - - Acetyltransferase (GNAT) domain
HEBBHNLP_01505 9.56e-89 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
HEBBHNLP_01506 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HEBBHNLP_01507 6.08e-163 - - - - - - - -
HEBBHNLP_01508 1.12e-288 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HEBBHNLP_01509 2.1e-308 ydhD - - M - - - Glycosyl hydrolase
HEBBHNLP_01510 7.45e-158 ydhC - - K - - - FCD
HEBBHNLP_01511 1.02e-154 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
HEBBHNLP_01512 4.02e-265 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
HEBBHNLP_01513 1.9e-89 - - - K - - - Winged helix DNA-binding domain
HEBBHNLP_01514 6.42e-147 ydgI - - C - - - nitroreductase
HEBBHNLP_01515 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
HEBBHNLP_01516 1.35e-102 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEBBHNLP_01517 3.3e-115 - - - S - - - DinB family
HEBBHNLP_01518 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HEBBHNLP_01519 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
HEBBHNLP_01520 1.34e-109 yycN - - K - - - Acetyltransferase
HEBBHNLP_01521 1.16e-69 - - - S - - - DoxX-like family
HEBBHNLP_01522 5.74e-126 ydgC - - K - - - Bacterial regulatory proteins, tetR family
HEBBHNLP_01523 8.97e-47 ydgB - - S - - - Spore germination protein gerPA/gerPF
HEBBHNLP_01524 1.53e-47 ydgA - - S - - - Spore germination protein gerPA/gerPF
HEBBHNLP_01525 2.57e-89 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HEBBHNLP_01526 4.32e-94 ydfS - - S - - - Protein of unknown function (DUF421)
HEBBHNLP_01527 1.91e-10 ydfS - - S - - - Protein of unknown function (DUF421)
HEBBHNLP_01528 9.94e-40 ydfR - - S - - - Protein of unknown function (DUF421)
HEBBHNLP_01529 3.24e-59 ydfR - - S - - - Protein of unknown function (DUF421)
HEBBHNLP_01531 7.9e-41 - - - - - - - -
HEBBHNLP_01532 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
HEBBHNLP_01533 6.28e-73 ydfQ - - CO - - - Thioredoxin
HEBBHNLP_01534 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
HEBBHNLP_01535 3.18e-237 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HEBBHNLP_01536 6.41e-141 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
HEBBHNLP_01537 5.22e-199 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEBBHNLP_01538 4.62e-184 - - - K - - - Bacterial transcription activator, effector binding domain
HEBBHNLP_01539 2.27e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HEBBHNLP_01540 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
HEBBHNLP_01541 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEBBHNLP_01542 3.32e-236 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEBBHNLP_01544 3.92e-104 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HEBBHNLP_01545 1.5e-158 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HEBBHNLP_01546 9.91e-150 ydfE - - S - - - Flavin reductase like domain
HEBBHNLP_01547 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEBBHNLP_01548 5.78e-189 - - - EG - - - EamA-like transporter family
HEBBHNLP_01549 1.52e-154 - - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
HEBBHNLP_01550 7.61e-279 - - - T - - - GHKL domain
HEBBHNLP_01551 3.58e-199 - - - - - - - -
HEBBHNLP_01552 9.78e-156 nodB1 - - G - - - deacetylase
HEBBHNLP_01553 3.22e-189 - - - K - - - Transcriptional regulator
HEBBHNLP_01554 1.1e-184 - - - J - - - GNAT acetyltransferase
HEBBHNLP_01555 7.13e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HEBBHNLP_01556 3e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
HEBBHNLP_01557 6.56e-194 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HEBBHNLP_01558 4.3e-74 - - - K - - - HxlR-like helix-turn-helix
HEBBHNLP_01559 6.79e-135 - - - S ko:K07002 - ko00000 Serine hydrolase
HEBBHNLP_01560 4.3e-96 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
HEBBHNLP_01561 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEBBHNLP_01562 5.43e-196 ydeK - - EG - - - -transporter
HEBBHNLP_01564 1.27e-142 - - - - - - - -
HEBBHNLP_01565 3.88e-93 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
HEBBHNLP_01566 5.9e-79 ydeH - - - - - - -
HEBBHNLP_01567 6.57e-278 ydeG - - EGP - - - Major facilitator superfamily
HEBBHNLP_01568 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEBBHNLP_01569 3.48e-210 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
HEBBHNLP_01570 1.71e-215 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HEBBHNLP_01571 5.74e-205 - - - K - - - AraC-like ligand binding domain
HEBBHNLP_01572 6.72e-41 ydzE - - EG - - - spore germination
HEBBHNLP_01573 8.42e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
HEBBHNLP_01574 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
HEBBHNLP_01575 2.36e-245 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
HEBBHNLP_01577 2.51e-45 - - - S - - - Putative amidase domain
HEBBHNLP_01578 6.39e-138 - - - M - - - nucleic acid phosphodiester bond hydrolysis
HEBBHNLP_01579 2.31e-24 - - - S - - - LXG domain of WXG superfamily
HEBBHNLP_01580 9.42e-57 - - - - - - - -
HEBBHNLP_01581 8.25e-63 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
HEBBHNLP_01582 4.35e-284 ydeG3 - - EGP - - - Major Facilitator Superfamily
HEBBHNLP_01583 7.76e-184 yddR - - S - - - Zn-dependent hydrolases of the beta-lactamase fold
HEBBHNLP_01584 2.7e-127 yddQ - - Q - - - Isochorismatase family
HEBBHNLP_01585 5.12e-101 lrpB - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
HEBBHNLP_01586 8.15e-94 lrpA - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
HEBBHNLP_01587 8.14e-240 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEBBHNLP_01595 3.74e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HEBBHNLP_01596 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
HEBBHNLP_01597 1.79e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEBBHNLP_01598 1.08e-105 ydcG - - S - - - EVE domain
HEBBHNLP_01601 1.53e-140 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
HEBBHNLP_01602 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEBBHNLP_01603 8.3e-110 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HEBBHNLP_01604 3.98e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
HEBBHNLP_01605 1.08e-242 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
HEBBHNLP_01606 2.45e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HEBBHNLP_01607 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
HEBBHNLP_01608 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
HEBBHNLP_01609 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HEBBHNLP_01610 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HEBBHNLP_01611 1.77e-282 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEBBHNLP_01612 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
HEBBHNLP_01613 1.6e-77 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HEBBHNLP_01614 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
HEBBHNLP_01615 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
HEBBHNLP_01616 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
HEBBHNLP_01617 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HEBBHNLP_01618 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HEBBHNLP_01619 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HEBBHNLP_01620 4.19e-75 ydbP - - CO - - - Thioredoxin
HEBBHNLP_01621 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEBBHNLP_01622 2.1e-11 - - - S - - - Fur-regulated basic protein A
HEBBHNLP_01623 1.49e-26 - - - S - - - Fur-regulated basic protein B
HEBBHNLP_01624 7.15e-278 ydbM - - I - - - acyl-CoA dehydrogenase
HEBBHNLP_01625 9.32e-70 ydbL - - - - - - -
HEBBHNLP_01626 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HEBBHNLP_01627 2.66e-218 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEBBHNLP_01628 3.25e-231 ydbI - - S - - - AI-2E family transporter
HEBBHNLP_01629 1.8e-289 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEBBHNLP_01630 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
HEBBHNLP_01631 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HEBBHNLP_01632 4.28e-252 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HEBBHNLP_01633 2.24e-197 ydbD - - P ko:K07217 - ko00000 Catalase
HEBBHNLP_01634 2.58e-82 ydbC - - S - - - Domain of unknown function (DUF4937
HEBBHNLP_01635 1.26e-77 ydbB - - G - - - Cupin domain
HEBBHNLP_01636 3.3e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
HEBBHNLP_01637 4.3e-190 ydbA - - P - - - EcsC protein family
HEBBHNLP_01638 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HEBBHNLP_01639 1.67e-42 ydaS - - S - - - membrane
HEBBHNLP_01640 7.87e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HEBBHNLP_01641 2.14e-53 - - - - - - - -
HEBBHNLP_01643 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HEBBHNLP_01644 1.21e-97 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HEBBHNLP_01645 0.0 ydaO - - E - - - amino acid
HEBBHNLP_01646 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
HEBBHNLP_01647 6.45e-303 ydaM - - M - - - Glycosyl transferase family group 2
HEBBHNLP_01648 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
HEBBHNLP_01649 2.12e-191 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
HEBBHNLP_01650 8.13e-263 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
HEBBHNLP_01651 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEBBHNLP_01652 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
HEBBHNLP_01653 1.88e-62 ydzA - - EGP - - - Domain of unknown function (DUF3817)
HEBBHNLP_01654 5.35e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HEBBHNLP_01655 5.24e-101 ydaG - - S - - - general stress protein
HEBBHNLP_01656 1.96e-126 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HEBBHNLP_01657 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
HEBBHNLP_01658 1.07e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBBHNLP_01659 8.25e-127 ydaC - - Q - - - Methyltransferase domain
HEBBHNLP_01660 0.0 ydaB - - IQ - - - acyl-CoA ligase
HEBBHNLP_01661 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
HEBBHNLP_01662 2.57e-221 ycsN - - S - - - Oxidoreductase
HEBBHNLP_01663 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
HEBBHNLP_01664 3.66e-64 yczJ - - S - - - biosynthesis
HEBBHNLP_01666 2.61e-148 ycsK - - E - - - anatomical structure formation involved in morphogenesis
HEBBHNLP_01667 1.55e-170 kipR - - K - - - Transcriptional regulator
HEBBHNLP_01668 3.31e-237 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
HEBBHNLP_01669 2.05e-172 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
HEBBHNLP_01670 3.33e-188 ycsI - - S - - - Belongs to the D-glutamate cyclase family
HEBBHNLP_01671 2.66e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
HEBBHNLP_01672 2.58e-179 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
HEBBHNLP_01673 5.44e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
HEBBHNLP_01675 7.69e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
HEBBHNLP_01676 2.32e-107 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
HEBBHNLP_01677 1.25e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HEBBHNLP_01679 1.68e-255 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
HEBBHNLP_01680 8.5e-266 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
HEBBHNLP_01681 4.81e-94 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HEBBHNLP_01682 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
HEBBHNLP_01683 1.34e-74 - - - - - - - -
HEBBHNLP_01684 1.22e-137 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HEBBHNLP_01685 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
HEBBHNLP_01686 3.99e-134 ycnI - - S - - - protein conserved in bacteria
HEBBHNLP_01687 3.41e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBBHNLP_01688 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
HEBBHNLP_01689 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEBBHNLP_01690 1.62e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEBBHNLP_01691 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEBBHNLP_01692 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HEBBHNLP_01693 4.82e-60 ycnE - - S - - - Monooxygenase
HEBBHNLP_01694 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HEBBHNLP_01695 2.91e-198 ycnC - - K - - - Transcriptional regulator
HEBBHNLP_01696 0.0 ycnB - - EGP - - - the major facilitator superfamily
HEBBHNLP_01697 2.43e-214 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
HEBBHNLP_01698 5.63e-176 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEBBHNLP_01699 4.69e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBBHNLP_01700 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBBHNLP_01701 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HEBBHNLP_01702 6.5e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HEBBHNLP_01703 1.58e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HEBBHNLP_01705 1.15e-102 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HEBBHNLP_01706 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HEBBHNLP_01707 5.99e-164 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBBHNLP_01708 2.59e-274 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
HEBBHNLP_01709 1.18e-155 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HEBBHNLP_01710 3.8e-253 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
HEBBHNLP_01711 8.35e-297 gerKC - - S ko:K06297 - ko00000 spore germination
HEBBHNLP_01712 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
HEBBHNLP_01714 0.0 yclG - - M - - - Pectate lyase superfamily protein
HEBBHNLP_01715 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
HEBBHNLP_01716 1.92e-202 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
HEBBHNLP_01717 1.45e-107 yclD - - - - - - -
HEBBHNLP_01718 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
HEBBHNLP_01719 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HEBBHNLP_01720 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HEBBHNLP_01721 5.32e-209 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
HEBBHNLP_01722 3.03e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HEBBHNLP_01723 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HEBBHNLP_01724 2.9e-171 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HEBBHNLP_01725 8.71e-148 yczE - - S ko:K07149 - ko00000 membrane
HEBBHNLP_01726 4.76e-145 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
HEBBHNLP_01727 0.0 ycxD - - K - - - GntR family transcriptional regulator
HEBBHNLP_01728 8.03e-206 ycxC - - EG - - - EamA-like transporter family
HEBBHNLP_01729 3.79e-125 - - - S - - - YcxB-like protein
HEBBHNLP_01730 1.47e-286 - - - EGP - - - Major Facilitator Superfamily
HEBBHNLP_01731 3.3e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
HEBBHNLP_01732 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
HEBBHNLP_01733 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBBHNLP_01734 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBBHNLP_01735 6.05e-86 hxlR - - K - - - transcriptional
HEBBHNLP_01736 6.57e-136 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
HEBBHNLP_01737 1.32e-125 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
HEBBHNLP_01738 1.52e-267 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HEBBHNLP_01739 7.94e-100 nucA - - M - - - Deoxyribonuclease NucA/NucB
HEBBHNLP_01740 5.81e-92 nin - - S - - - Competence protein J (ComJ)
HEBBHNLP_01741 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEBBHNLP_01742 1.16e-154 - - - S - - - AAA domain
HEBBHNLP_01743 9e-32 - - - - - - - -
HEBBHNLP_01744 7.43e-58 - - - K - - - MarR family
HEBBHNLP_01745 6.85e-67 yckD - - S - - - Protein of unknown function (DUF2680)
HEBBHNLP_01746 4.7e-98 yckC - - S - - - membrane
HEBBHNLP_01748 3.6e-185 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HEBBHNLP_01749 2.99e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HEBBHNLP_01750 3.6e-286 yciC - - S - - - GTPases (G3E family)
HEBBHNLP_01751 2.21e-128 - - - M - - - ErfK YbiS YcfS YnhG
HEBBHNLP_01752 4.09e-220 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
HEBBHNLP_01753 3.18e-282 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
HEBBHNLP_01754 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
HEBBHNLP_01755 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEBBHNLP_01756 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HEBBHNLP_01757 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
HEBBHNLP_01758 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
HEBBHNLP_01759 2.52e-237 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HEBBHNLP_01760 2.42e-202 ycgS - - I - - - alpha/beta hydrolase fold
HEBBHNLP_01761 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
HEBBHNLP_01762 1.05e-192 ycgQ - - S ko:K08986 - ko00000 membrane
HEBBHNLP_01763 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
HEBBHNLP_01764 5.98e-315 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEBBHNLP_01765 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
HEBBHNLP_01766 8.56e-217 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
HEBBHNLP_01767 9.06e-186 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
HEBBHNLP_01768 1.56e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
HEBBHNLP_01769 8.95e-225 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
HEBBHNLP_01770 5.27e-186 - - - Q - - - ubiE/COQ5 methyltransferase family
HEBBHNLP_01771 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HEBBHNLP_01772 2.09e-137 tmrB - - S - - - AAA domain
HEBBHNLP_01773 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HEBBHNLP_01774 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
HEBBHNLP_01775 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HEBBHNLP_01776 1.03e-192 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
HEBBHNLP_01777 1.84e-146 ycgF - - E - - - Lysine exporter protein LysE YggA
HEBBHNLP_01778 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEBBHNLP_01779 0.0 mdr - - EGP - - - the major facilitator superfamily
HEBBHNLP_01780 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HEBBHNLP_01781 6.61e-230 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HEBBHNLP_01782 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
HEBBHNLP_01783 7.79e-105 ycgB - - - - - - -
HEBBHNLP_01784 0.0 ycgA - - S - - - Membrane
HEBBHNLP_01785 2.3e-275 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
HEBBHNLP_01786 2.01e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HEBBHNLP_01787 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HEBBHNLP_01788 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
HEBBHNLP_01789 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HEBBHNLP_01790 9.79e-260 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
HEBBHNLP_01791 1.1e-277 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
HEBBHNLP_01792 2.96e-245 yceH - - P - - - Belongs to the TelA family
HEBBHNLP_01793 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
HEBBHNLP_01794 4.1e-176 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
HEBBHNLP_01795 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
HEBBHNLP_01796 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
HEBBHNLP_01797 2.17e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
HEBBHNLP_01798 3.44e-237 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEBBHNLP_01799 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HEBBHNLP_01800 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HEBBHNLP_01801 7.92e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HEBBHNLP_01802 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HEBBHNLP_01803 6.85e-180 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
HEBBHNLP_01804 1.36e-246 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
HEBBHNLP_01805 2.18e-122 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HEBBHNLP_01806 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEBBHNLP_01807 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEBBHNLP_01808 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
HEBBHNLP_01809 1.37e-221 yccK - - C - - - Aldo keto reductase
HEBBHNLP_01810 1.8e-253 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HEBBHNLP_01811 2.2e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HEBBHNLP_01812 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HEBBHNLP_01813 3.27e-208 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HEBBHNLP_01814 1.01e-254 yccF - - K ko:K07039 - ko00000 SEC-C motif
HEBBHNLP_01815 2.69e-72 - - - S - - - RDD family
HEBBHNLP_01816 4e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
HEBBHNLP_01817 3.81e-254 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HEBBHNLP_01818 6.54e-132 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
HEBBHNLP_01819 1.24e-302 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
HEBBHNLP_01820 1.45e-260 ycbU - - E - - - Selenocysteine lyase
HEBBHNLP_01821 4.68e-152 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HEBBHNLP_01822 5.12e-158 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEBBHNLP_01823 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HEBBHNLP_01824 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
HEBBHNLP_01825 3.83e-174 ycbR - - T - - - vWA found in TerF C terminus
HEBBHNLP_01826 5.22e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
HEBBHNLP_01827 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
HEBBHNLP_01828 8.21e-148 - - - S - - - ABC-2 family transporter protein
HEBBHNLP_01829 1.07e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEBBHNLP_01830 2.17e-214 ycbM - - T - - - Histidine kinase
HEBBHNLP_01831 2.24e-161 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBBHNLP_01832 1.16e-214 eamA1 - - EG - - - spore germination
HEBBHNLP_01833 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
HEBBHNLP_01834 7.7e-226 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
HEBBHNLP_01835 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
HEBBHNLP_01836 2.3e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
HEBBHNLP_01837 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HEBBHNLP_01838 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HEBBHNLP_01839 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEBBHNLP_01840 1.67e-221 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
HEBBHNLP_01841 2.01e-216 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
HEBBHNLP_01842 1.96e-289 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEBBHNLP_01843 1.46e-236 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HEBBHNLP_01844 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
HEBBHNLP_01845 8.72e-232 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
HEBBHNLP_01846 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HEBBHNLP_01847 1.78e-258 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HEBBHNLP_01849 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
HEBBHNLP_01850 2.12e-174 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEBBHNLP_01851 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEBBHNLP_01852 6.04e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEBBHNLP_01853 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
HEBBHNLP_01854 1.58e-59 ybfN - - - - - - -
HEBBHNLP_01855 3.56e-189 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HEBBHNLP_01856 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
HEBBHNLP_01857 2.81e-123 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEBBHNLP_01858 3.6e-210 - - - S - - - Alpha/beta hydrolase family
HEBBHNLP_01860 4.14e-229 mpr - - M - - - Belongs to the peptidase S1B family
HEBBHNLP_01861 9.28e-271 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HEBBHNLP_01862 3.2e-89 - - - M - - - nucleic acid phosphodiester bond hydrolysis
HEBBHNLP_01863 1.15e-186 draG - - O - - - ADP-ribosylglycohydrolase
HEBBHNLP_01864 2.12e-187 ybfI - - K - - - AraC-like ligand binding domain
HEBBHNLP_01865 3.05e-207 ybfH - - EG - - - EamA-like transporter family
HEBBHNLP_01867 1.3e-284 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
HEBBHNLP_01868 7.04e-217 ybfA - - K - - - FR47-like protein
HEBBHNLP_01869 6.95e-45 - - - S - - - Protein of unknown function (DUF2651)
HEBBHNLP_01870 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
HEBBHNLP_01871 5.52e-208 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
HEBBHNLP_01872 0.0 ybeC - - E - - - amino acid
HEBBHNLP_01873 1.3e-53 ybyB - - - - - - -
HEBBHNLP_01874 3.8e-314 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
HEBBHNLP_01875 1.24e-191 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
HEBBHNLP_01876 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
HEBBHNLP_01877 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
HEBBHNLP_01878 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HEBBHNLP_01879 4.26e-272 ybdO - - S - - - Domain of unknown function (DUF4885)
HEBBHNLP_01880 6.07e-192 ybdN - - - - - - -
HEBBHNLP_01881 3.4e-179 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
HEBBHNLP_01883 9.98e-75 - - - - - - - -
HEBBHNLP_01884 2.57e-255 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
HEBBHNLP_01885 9.45e-67 - - - K - - - Helix-turn-helix domain
HEBBHNLP_01886 1.03e-79 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
HEBBHNLP_01887 1.6e-63 - - - - - - - -
HEBBHNLP_01888 4.5e-119 ybcF - - P - - - carbonic anhydrase
HEBBHNLP_01889 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
HEBBHNLP_01890 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HEBBHNLP_01891 6.48e-126 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Bacitracin ABC transporter permease
HEBBHNLP_01892 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HEBBHNLP_01893 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEBBHNLP_01894 1.02e-290 ybbR - - S - - - protein conserved in bacteria
HEBBHNLP_01895 8.63e-186 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEBBHNLP_01896 6.45e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HEBBHNLP_01897 1.87e-126 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEBBHNLP_01903 2.43e-100 ybbK - - S - - - Protein of unknown function (DUF523)
HEBBHNLP_01904 3.13e-114 ybbJ - - J - - - acetyltransferase
HEBBHNLP_01905 1.35e-209 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HEBBHNLP_01906 2.12e-191 ybbH - - K - - - transcriptional
HEBBHNLP_01907 2.09e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEBBHNLP_01908 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
HEBBHNLP_01909 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
HEBBHNLP_01910 2.33e-302 ybbC - - S - - - protein conserved in bacteria
HEBBHNLP_01911 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
HEBBHNLP_01912 7.27e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
HEBBHNLP_01913 2.88e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBBHNLP_01914 3.51e-228 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBBHNLP_01915 5.64e-175 ybbA - - S ko:K07017 - ko00000 Putative esterase
HEBBHNLP_01916 7.61e-203 ybaS - - S - - - Na -dependent transporter
HEBBHNLP_01918 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
HEBBHNLP_01919 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HEBBHNLP_01926 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HEBBHNLP_01927 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HEBBHNLP_01928 8.69e-181 pdaB - - G - - - Polysaccharide deacetylase
HEBBHNLP_01929 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
HEBBHNLP_01930 1.04e-122 gerD - - - ko:K06294 - ko00000 -
HEBBHNLP_01931 4.47e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HEBBHNLP_01932 1.29e-169 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HEBBHNLP_01933 2.96e-90 ybaK - - S - - - Protein of unknown function (DUF2521)
HEBBHNLP_01934 2.4e-183 ybaJ - - Q - - - Methyltransferase domain
HEBBHNLP_01935 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HEBBHNLP_01936 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HEBBHNLP_01937 7.18e-181 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HEBBHNLP_01938 1.53e-175 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEBBHNLP_01939 4.47e-196 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEBBHNLP_01940 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEBBHNLP_01941 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HEBBHNLP_01942 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEBBHNLP_01943 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HEBBHNLP_01944 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HEBBHNLP_01945 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HEBBHNLP_01946 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HEBBHNLP_01947 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HEBBHNLP_01948 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HEBBHNLP_01949 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HEBBHNLP_01950 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HEBBHNLP_01951 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HEBBHNLP_01952 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HEBBHNLP_01953 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HEBBHNLP_01954 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HEBBHNLP_01955 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HEBBHNLP_01956 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEBBHNLP_01957 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HEBBHNLP_01958 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HEBBHNLP_01959 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HEBBHNLP_01960 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HEBBHNLP_01961 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HEBBHNLP_01962 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HEBBHNLP_01963 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HEBBHNLP_01964 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HEBBHNLP_01965 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HEBBHNLP_01966 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HEBBHNLP_01967 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HEBBHNLP_01968 7.98e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HEBBHNLP_01969 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HEBBHNLP_01970 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HEBBHNLP_01971 2.13e-229 ybaC - - S - - - Alpha/beta hydrolase family
HEBBHNLP_01972 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HEBBHNLP_01973 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HEBBHNLP_01974 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HEBBHNLP_01975 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HEBBHNLP_01976 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
HEBBHNLP_01977 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEBBHNLP_01978 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEBBHNLP_01979 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HEBBHNLP_01980 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HEBBHNLP_01981 1.16e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HEBBHNLP_01982 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HEBBHNLP_01983 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HEBBHNLP_01984 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HEBBHNLP_01985 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HEBBHNLP_01986 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
HEBBHNLP_01987 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
HEBBHNLP_01988 3.52e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEBBHNLP_01989 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HEBBHNLP_01990 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HEBBHNLP_01991 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
HEBBHNLP_01992 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HEBBHNLP_01993 9.02e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HEBBHNLP_01994 3.53e-160 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HEBBHNLP_01995 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
HEBBHNLP_01996 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HEBBHNLP_01997 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HEBBHNLP_01998 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
HEBBHNLP_01999 3.15e-256 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HEBBHNLP_02000 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
HEBBHNLP_02001 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HEBBHNLP_02002 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HEBBHNLP_02012 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HEBBHNLP_02013 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HEBBHNLP_02014 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEBBHNLP_02015 1.81e-41 yazB - - K - - - transcriptional
HEBBHNLP_02016 2.64e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HEBBHNLP_02017 6.31e-79 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HEBBHNLP_02018 2.73e-204 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HEBBHNLP_02019 6.25e-214 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
HEBBHNLP_02020 4.92e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
HEBBHNLP_02021 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HEBBHNLP_02022 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HEBBHNLP_02023 7.8e-195 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
HEBBHNLP_02024 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HEBBHNLP_02025 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HEBBHNLP_02026 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEBBHNLP_02027 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
HEBBHNLP_02028 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HEBBHNLP_02029 1.2e-236 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
HEBBHNLP_02030 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HEBBHNLP_02031 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
HEBBHNLP_02034 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
HEBBHNLP_02035 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HEBBHNLP_02036 1.49e-137 yabQ - - S - - - spore cortex biosynthesis protein
HEBBHNLP_02037 1.91e-66 yabP - - S - - - Sporulation protein YabP
HEBBHNLP_02038 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HEBBHNLP_02039 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HEBBHNLP_02040 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEBBHNLP_02041 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
HEBBHNLP_02042 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HEBBHNLP_02043 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
HEBBHNLP_02044 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HEBBHNLP_02045 1.19e-135 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HEBBHNLP_02046 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEBBHNLP_02047 2.58e-309 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HEBBHNLP_02049 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HEBBHNLP_02050 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
HEBBHNLP_02051 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HEBBHNLP_02052 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HEBBHNLP_02053 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
HEBBHNLP_02054 5.32e-53 veg - - S - - - protein conserved in bacteria
HEBBHNLP_02055 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
HEBBHNLP_02056 2.05e-198 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HEBBHNLP_02057 5.81e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HEBBHNLP_02058 1.67e-277 yabE - - T - - - protein conserved in bacteria
HEBBHNLP_02059 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
HEBBHNLP_02060 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEBBHNLP_02061 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
HEBBHNLP_02062 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HEBBHNLP_02063 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
HEBBHNLP_02064 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
HEBBHNLP_02065 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
HEBBHNLP_02066 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
HEBBHNLP_02067 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HEBBHNLP_02068 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
HEBBHNLP_02069 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
HEBBHNLP_02070 4.67e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HEBBHNLP_02071 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
HEBBHNLP_02072 4.15e-259 yaaN - - P - - - Belongs to the TelA family
HEBBHNLP_02073 1.56e-131 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HEBBHNLP_02074 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
HEBBHNLP_02077 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HEBBHNLP_02078 2.16e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
HEBBHNLP_02079 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
HEBBHNLP_02080 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HEBBHNLP_02081 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HEBBHNLP_02082 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEBBHNLP_02083 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HEBBHNLP_02084 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
HEBBHNLP_02085 2.99e-275 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
HEBBHNLP_02086 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
HEBBHNLP_02087 1.25e-157 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
HEBBHNLP_02089 1.14e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HEBBHNLP_02090 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HEBBHNLP_02091 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HEBBHNLP_02092 3.75e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HEBBHNLP_02093 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HEBBHNLP_02094 3.04e-232 yaaC - - S - - - YaaC-like Protein
HEBBHNLP_02097 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HEBBHNLP_02098 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEBBHNLP_02099 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEBBHNLP_02100 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
HEBBHNLP_02101 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HEBBHNLP_02102 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
HEBBHNLP_02103 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HEBBHNLP_02104 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HEBBHNLP_02105 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HEBBHNLP_02106 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEBBHNLP_02107 2.14e-140 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
HEBBHNLP_02108 1.81e-316 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HEBBHNLP_02109 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HEBBHNLP_02110 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HEBBHNLP_02111 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HEBBHNLP_02112 1.32e-97 - - - S - - - Bacterial PH domain
HEBBHNLP_02113 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
HEBBHNLP_02114 2.29e-190 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HEBBHNLP_02115 7.52e-144 yyaC - - S - - - Sporulation protein YyaC
HEBBHNLP_02116 3.09e-226 yyaD - - S - - - Membrane
HEBBHNLP_02117 7.41e-45 yyzM - - S - - - protein conserved in bacteria
HEBBHNLP_02118 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEBBHNLP_02119 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HEBBHNLP_02120 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HEBBHNLP_02121 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HEBBHNLP_02122 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HEBBHNLP_02123 9.83e-186 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HEBBHNLP_02124 7.15e-229 ccpB - - K - - - Transcriptional regulator
HEBBHNLP_02125 4.17e-89 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEBBHNLP_02126 3.66e-127 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
HEBBHNLP_02127 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
HEBBHNLP_02128 5.15e-216 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
HEBBHNLP_02129 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
HEBBHNLP_02130 4.27e-137 yyaP - - H - - - RibD C-terminal domain
HEBBHNLP_02131 2.58e-86 - - - S - - - YjbR
HEBBHNLP_02132 4.18e-123 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
HEBBHNLP_02133 7.09e-124 yyaS - - S ko:K07149 - ko00000 Membrane
HEBBHNLP_02134 1.25e-91 yjcF - - S - - - Acetyltransferase (GNAT) domain
HEBBHNLP_02135 4.54e-100 yybA - - K - - - transcriptional
HEBBHNLP_02136 8.78e-164 - - - S - - - Metallo-beta-lactamase superfamily
HEBBHNLP_02137 8.72e-68 - - - E - - - COG0346 Lactoylglutathione lyase and related lyases
HEBBHNLP_02138 4.78e-111 - - - E - - - LysE type translocator
HEBBHNLP_02139 2.71e-184 - - - K - - - LysR substrate binding domain
HEBBHNLP_02140 5.55e-94 yybC - - - - - - -
HEBBHNLP_02141 1.21e-98 yjcF - - S - - - Acetyltransferase (GNAT) domain
HEBBHNLP_02142 4.38e-209 yybE - - K - - - Transcriptional regulator
HEBBHNLP_02143 1.75e-276 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HEBBHNLP_02144 3.28e-161 yybG - - S - - - Pentapeptide repeat-containing protein
HEBBHNLP_02145 5.02e-87 - - - S - - - SnoaL-like domain
HEBBHNLP_02146 2.91e-183 - - - - - - - -
HEBBHNLP_02147 5.1e-141 - - - K - - - TipAS antibiotic-recognition domain
HEBBHNLP_02148 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HEBBHNLP_02150 7.84e-91 - - - - - - - -
HEBBHNLP_02151 5.7e-209 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
HEBBHNLP_02152 6.68e-90 yybR - - K - - - Transcriptional regulator
HEBBHNLP_02153 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
HEBBHNLP_02155 2.56e-145 yybS - - S - - - membrane
HEBBHNLP_02156 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HEBBHNLP_02157 6.45e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HEBBHNLP_02158 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEBBHNLP_02159 9.87e-282 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
HEBBHNLP_02160 1.89e-22 yycC - - K - - - YycC-like protein
HEBBHNLP_02162 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HEBBHNLP_02163 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HEBBHNLP_02164 5.69e-100 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEBBHNLP_02165 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HEBBHNLP_02170 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBBHNLP_02171 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEBBHNLP_02172 0.0 yycH - - S - - - protein conserved in bacteria
HEBBHNLP_02173 1.2e-200 yycI - - S - - - protein conserved in bacteria
HEBBHNLP_02174 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HEBBHNLP_02175 7.75e-278 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEBBHNLP_02176 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HEBBHNLP_02177 5.84e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
HEBBHNLP_02178 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HEBBHNLP_02179 1.86e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
HEBBHNLP_02181 1.44e-237 - - - S - - - aspartate phosphatase
HEBBHNLP_02182 3.69e-111 yycN - - K - - - Acetyltransferase
HEBBHNLP_02183 3.95e-168 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HEBBHNLP_02184 1.78e-265 yycP - - - - - - -
HEBBHNLP_02185 1.92e-42 yycQ - - S - - - Protein of unknown function (DUF2651)
HEBBHNLP_02187 2.12e-296 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HEBBHNLP_02188 2.93e-83 - - - - - - - -
HEBBHNLP_02190 8.3e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HEBBHNLP_02192 8.92e-190 - 2.1.1.113 - L ko:K00590 - ko00000,ko01000,ko02048 DNA methylase
HEBBHNLP_02193 3.02e-189 - - - L - - - Putative RNA methylase family UPF0020
HEBBHNLP_02194 1.04e-147 - - - V - - - HNH endonuclease
HEBBHNLP_02195 1.93e-12 - - - - - - - -
HEBBHNLP_02196 2.15e-33 - - - L ko:K03630 - ko00000 RadC-like JAB domain
HEBBHNLP_02197 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
HEBBHNLP_02198 5.67e-141 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEBBHNLP_02199 5.49e-152 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HEBBHNLP_02200 1.44e-24 - - - - - - - -
HEBBHNLP_02203 1.86e-196 - - - - - - - -
HEBBHNLP_02204 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
HEBBHNLP_02205 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
HEBBHNLP_02206 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEBBHNLP_02207 1.18e-294 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HEBBHNLP_02208 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HEBBHNLP_02209 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
HEBBHNLP_02210 2.72e-262 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HEBBHNLP_02211 6e-244 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
HEBBHNLP_02212 2.19e-153 yxaC - - M - - - effector of murein hydrolase
HEBBHNLP_02213 1.03e-77 - - - S ko:K06518 - ko00000,ko02000 LrgA family
HEBBHNLP_02214 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEBBHNLP_02215 3.53e-254 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBBHNLP_02216 3.22e-129 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
HEBBHNLP_02217 1.05e-250 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
HEBBHNLP_02218 1.08e-285 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
HEBBHNLP_02219 4.03e-99 yxaI - - S - - - membrane protein domain
HEBBHNLP_02220 3.11e-80 - - - S - - - Family of unknown function (DUF5391)
HEBBHNLP_02221 7.49e-137 yxaL - - S - - - PQQ-like domain
HEBBHNLP_02222 6.28e-40 yxaI - - S - - - membrane protein domain
HEBBHNLP_02223 8.39e-314 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HEBBHNLP_02224 4.39e-267 yxbF - - K - - - Bacterial regulatory proteins, tetR family
HEBBHNLP_02225 4.85e-192 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HEBBHNLP_02227 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
HEBBHNLP_02228 2.68e-309 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEBBHNLP_02229 9.41e-105 - - - T - - - HPP family
HEBBHNLP_02230 1.1e-114 - - - S - - - CGNR zinc finger
HEBBHNLP_02232 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
HEBBHNLP_02234 7.1e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
HEBBHNLP_02235 6.35e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HEBBHNLP_02236 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEBBHNLP_02237 4.03e-199 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HEBBHNLP_02238 1.01e-226 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HEBBHNLP_02239 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HEBBHNLP_02240 4.99e-222 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HEBBHNLP_02241 8.46e-298 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
HEBBHNLP_02242 1.55e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HEBBHNLP_02243 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
HEBBHNLP_02244 3.26e-193 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HEBBHNLP_02245 2.43e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HEBBHNLP_02246 1.62e-159 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBBHNLP_02247 2.59e-229 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEBBHNLP_02248 4.46e-180 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HEBBHNLP_02249 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
HEBBHNLP_02250 1.2e-76 yxeA - - S - - - Protein of unknown function (DUF1093)
HEBBHNLP_02251 1.43e-224 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEBBHNLP_02252 9.65e-91 - - - - - - - -
HEBBHNLP_02253 7.57e-28 yxeD - - - - - - -
HEBBHNLP_02254 7.32e-42 yxeE - - - - - - -
HEBBHNLP_02257 2.71e-192 yxeH - - S - - - hydrolases of the HAD superfamily
HEBBHNLP_02258 3.87e-237 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
HEBBHNLP_02259 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEBBHNLP_02260 5.16e-120 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEBBHNLP_02261 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HEBBHNLP_02262 4.97e-147 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HEBBHNLP_02263 3.94e-170 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEBBHNLP_02264 1.95e-270 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
HEBBHNLP_02265 1.69e-313 yxeQ - - S - - - MmgE/PrpD family
HEBBHNLP_02266 5.21e-254 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
HEBBHNLP_02267 1.51e-196 - - - S - - - Domain of Unknown Function (DUF1206)
HEBBHNLP_02268 1.22e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HEBBHNLP_02269 8.3e-150 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HEBBHNLP_02270 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEBBHNLP_02271 4.69e-298 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
HEBBHNLP_02272 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HEBBHNLP_02273 4.65e-229 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HEBBHNLP_02274 7.47e-298 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
HEBBHNLP_02275 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HEBBHNLP_02276 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
HEBBHNLP_02277 1.66e-101 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HEBBHNLP_02278 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
HEBBHNLP_02279 1.78e-35 - - - S - - - Domain of unknown function (DUF5082)
HEBBHNLP_02280 1.33e-52 yxiC - - S - - - Family of unknown function (DUF5344)
HEBBHNLP_02281 8.61e-156 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
HEBBHNLP_02283 2.81e-26 - - - S - - - protein conserved in bacteria
HEBBHNLP_02285 1.15e-121 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
HEBBHNLP_02286 5.77e-153 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
HEBBHNLP_02287 7.61e-102 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
HEBBHNLP_02288 8.98e-61 - - - - - - - -
HEBBHNLP_02289 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEBBHNLP_02290 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEBBHNLP_02291 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
HEBBHNLP_02292 2.82e-192 yxxF - - EG - - - EamA-like transporter family
HEBBHNLP_02293 0.0 wapA - - M - - - COG3209 Rhs family protein
HEBBHNLP_02294 1.27e-69 - - - - - - - -
HEBBHNLP_02296 6.95e-159 - - - - - - - -
HEBBHNLP_02297 1.24e-72 - - - S - - - Protein of unknown function (DUF4240)
HEBBHNLP_02298 5.79e-30 - - - S - - - Protein of unknown function (DUF4240)
HEBBHNLP_02299 3.53e-100 - - - - - - - -
HEBBHNLP_02300 1.9e-88 yxiG - - - - - - -
HEBBHNLP_02301 2.78e-67 yxxG - - - - - - -
HEBBHNLP_02302 6.09e-50 - - - S - - - Protein of unknown function (DUF2750)
HEBBHNLP_02305 2.07e-174 - - - - - - - -
HEBBHNLP_02306 2.19e-106 yxiI - - S - - - Protein of unknown function (DUF2716)
HEBBHNLP_02307 1.83e-43 - - - - - - - -
HEBBHNLP_02310 7.02e-59 yxiJ - - S - - - YxiJ-like protein
HEBBHNLP_02313 5.65e-80 - - - S - - - Protein of unknown function (DUF2812)
HEBBHNLP_02314 4.05e-69 - - - K - - - Transcriptional regulator PadR-like family
HEBBHNLP_02315 2.28e-270 - - - E - - - GDSL-like Lipase/Acylhydrolase
HEBBHNLP_02316 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HEBBHNLP_02317 7.67e-292 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
HEBBHNLP_02318 1.25e-141 - - - - - - - -
HEBBHNLP_02319 9.39e-192 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HEBBHNLP_02320 1.77e-183 bglS - - M - - - licheninase activity
HEBBHNLP_02321 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HEBBHNLP_02322 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HEBBHNLP_02323 2.28e-63 yxiS - - - - - - -
HEBBHNLP_02324 1.03e-133 - - - T - - - Domain of unknown function (DUF4163)
HEBBHNLP_02325 2.98e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEBBHNLP_02326 1.1e-197 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
HEBBHNLP_02327 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
HEBBHNLP_02328 6.6e-168 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HEBBHNLP_02329 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HEBBHNLP_02330 1.67e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HEBBHNLP_02331 1.09e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HEBBHNLP_02332 1.01e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HEBBHNLP_02333 4.98e-112 yxjI - - S - - - LURP-one-related
HEBBHNLP_02335 1.83e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HEBBHNLP_02336 3.52e-144 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
HEBBHNLP_02337 4.03e-242 - - - T - - - Signal transduction histidine kinase
HEBBHNLP_02338 6.58e-101 - - - S - - - Protein of unknown function (DUF1453)
HEBBHNLP_02339 6.06e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HEBBHNLP_02340 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEBBHNLP_02341 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEBBHNLP_02342 2.35e-211 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
HEBBHNLP_02343 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEBBHNLP_02344 2.15e-198 yxkH - - G - - - Polysaccharide deacetylase
HEBBHNLP_02346 0.0 - - - O - - - Peptidase family M48
HEBBHNLP_02347 9.34e-309 cimH - - C - - - COG3493 Na citrate symporter
HEBBHNLP_02348 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
HEBBHNLP_02349 4.54e-241 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
HEBBHNLP_02350 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
HEBBHNLP_02351 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
HEBBHNLP_02352 1.25e-200 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HEBBHNLP_02353 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
HEBBHNLP_02354 2.6e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEBBHNLP_02355 8.82e-59 yxlC - - S - - - Family of unknown function (DUF5345)
HEBBHNLP_02356 1.63e-39 - - - - - - - -
HEBBHNLP_02357 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
HEBBHNLP_02358 2.45e-212 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEBBHNLP_02359 1.61e-178 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HEBBHNLP_02360 8.28e-273 yxlH - - EGP - - - Major Facilitator Superfamily
HEBBHNLP_02361 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HEBBHNLP_02362 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HEBBHNLP_02363 8.94e-28 yxzF - - - - - - -
HEBBHNLP_02364 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
HEBBHNLP_02365 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
HEBBHNLP_02366 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEBBHNLP_02367 6.85e-67 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEBBHNLP_02368 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HEBBHNLP_02369 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HEBBHNLP_02370 8.34e-178 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBBHNLP_02371 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HEBBHNLP_02372 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBBHNLP_02373 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
HEBBHNLP_02374 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBBHNLP_02375 5.7e-210 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
HEBBHNLP_02376 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
HEBBHNLP_02377 4.57e-316 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
HEBBHNLP_02378 5.23e-296 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEBBHNLP_02379 1.25e-114 ywaE - - K - - - Transcriptional regulator
HEBBHNLP_02380 1.04e-159 ywaF - - S - - - Integral membrane protein
HEBBHNLP_02381 6.27e-215 gspA - - M - - - General stress
HEBBHNLP_02382 3.03e-194 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HEBBHNLP_02383 4.15e-312 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEBBHNLP_02384 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HEBBHNLP_02385 4.3e-311 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEBBHNLP_02386 5.9e-160 ywbB - - S - - - Protein of unknown function (DUF2711)
HEBBHNLP_02387 1.99e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
HEBBHNLP_02388 3.57e-281 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
HEBBHNLP_02389 3.13e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
HEBBHNLP_02390 1.51e-279 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
HEBBHNLP_02391 1.21e-143 ywbG - - M - - - effector of murein hydrolase
HEBBHNLP_02392 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HEBBHNLP_02393 2.7e-203 ywbI - - K - - - Transcriptional regulator
HEBBHNLP_02394 3.25e-185 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HEBBHNLP_02395 1.49e-147 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HEBBHNLP_02396 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
HEBBHNLP_02397 6.21e-249 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
HEBBHNLP_02398 2.18e-308 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
HEBBHNLP_02399 1.32e-143 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
HEBBHNLP_02400 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEBBHNLP_02401 8.67e-64 ywcB - - S - - - Protein of unknown function, DUF485
HEBBHNLP_02403 3.42e-158 ywcC - - K - - - transcriptional regulator
HEBBHNLP_02404 9.15e-75 gtcA - - S - - - GtrA-like protein
HEBBHNLP_02405 7.27e-287 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HEBBHNLP_02406 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HEBBHNLP_02407 5.11e-49 ydaS - - S - - - membrane
HEBBHNLP_02408 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HEBBHNLP_02409 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HEBBHNLP_02410 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
HEBBHNLP_02411 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
HEBBHNLP_02412 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
HEBBHNLP_02413 2.6e-260 - - - S - - - Acetyltransferase
HEBBHNLP_02414 2.62e-238 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HEBBHNLP_02415 9.02e-176 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
HEBBHNLP_02416 4.69e-236 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEBBHNLP_02417 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HEBBHNLP_02419 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HEBBHNLP_02420 2.91e-180 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
HEBBHNLP_02421 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEBBHNLP_02422 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HEBBHNLP_02423 6.19e-39 ywdA - - - - - - -
HEBBHNLP_02424 2.21e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HEBBHNLP_02425 1.6e-75 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
HEBBHNLP_02426 4.8e-68 ywdD - - - - - - -
HEBBHNLP_02428 4.68e-192 ywdF - - S - - - Glycosyltransferase like family 2
HEBBHNLP_02429 2.71e-165 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HEBBHNLP_02430 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HEBBHNLP_02431 2.65e-64 ywdI - - S - - - Family of unknown function (DUF5327)
HEBBHNLP_02432 2.64e-303 ywdJ - - F - - - Xanthine uracil
HEBBHNLP_02433 1.59e-78 ywdK - - S - - - small membrane protein
HEBBHNLP_02434 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HEBBHNLP_02435 1.15e-186 spsA - - M - - - Spore Coat
HEBBHNLP_02436 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
HEBBHNLP_02437 1.07e-283 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
HEBBHNLP_02438 4.92e-209 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
HEBBHNLP_02439 1.6e-270 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
HEBBHNLP_02440 8.27e-163 spsF - - M ko:K07257 - ko00000 Spore Coat
HEBBHNLP_02441 2.84e-240 spsG - - M - - - Spore Coat
HEBBHNLP_02442 6.13e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HEBBHNLP_02443 2.14e-232 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HEBBHNLP_02444 1.11e-202 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HEBBHNLP_02445 3.73e-113 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
HEBBHNLP_02446 3.7e-101 - - - - - - - -
HEBBHNLP_02447 1.73e-309 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HEBBHNLP_02448 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
HEBBHNLP_02449 0.0 rocB - - E - - - arginine degradation protein
HEBBHNLP_02450 3.54e-316 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HEBBHNLP_02451 7.35e-273 ywfA - - EGP - - - -transporter
HEBBHNLP_02452 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HEBBHNLP_02453 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HEBBHNLP_02454 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBBHNLP_02455 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HEBBHNLP_02456 1.52e-265 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
HEBBHNLP_02457 1.74e-294 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
HEBBHNLP_02458 9.26e-174 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
HEBBHNLP_02459 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
HEBBHNLP_02460 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
HEBBHNLP_02461 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
HEBBHNLP_02462 1.02e-197 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HEBBHNLP_02463 7.47e-203 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
HEBBHNLP_02464 5.39e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
HEBBHNLP_02465 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
HEBBHNLP_02466 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
HEBBHNLP_02467 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
HEBBHNLP_02468 7.42e-102 yffB - - K - - - Transcriptional regulator
HEBBHNLP_02469 1.52e-300 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
HEBBHNLP_02471 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEBBHNLP_02472 1.76e-94 ywhA - - K - - - Transcriptional regulator
HEBBHNLP_02473 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
HEBBHNLP_02474 9.43e-154 ywhC - - S - - - Peptidase family M50
HEBBHNLP_02475 1.92e-123 ywhD - - S - - - YwhD family
HEBBHNLP_02476 2.1e-64 - - - - - - - -
HEBBHNLP_02477 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HEBBHNLP_02478 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HEBBHNLP_02479 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
HEBBHNLP_02480 2.17e-37 - - - S - - - Aminoacyl-tRNA editing domain
HEBBHNLP_02482 3.28e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HEBBHNLP_02483 3.26e-282 ywhK - - CO - - - amine dehydrogenase activity
HEBBHNLP_02484 9.89e-315 ywhL - - CO - - - amine dehydrogenase activity
HEBBHNLP_02486 1.55e-313 - - - L - - - Peptidase, M16
HEBBHNLP_02487 1.46e-277 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
HEBBHNLP_02488 4.17e-298 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
HEBBHNLP_02489 3.03e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HEBBHNLP_02491 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
HEBBHNLP_02492 3.71e-12 - - - S - - - Bacteriocin subtilosin A
HEBBHNLP_02493 7.7e-95 ywiB - - S - - - protein conserved in bacteria
HEBBHNLP_02494 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HEBBHNLP_02495 1.2e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
HEBBHNLP_02496 3.27e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
HEBBHNLP_02497 1.84e-179 ywiC - - S - - - YwiC-like protein
HEBBHNLP_02498 3.53e-110 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
HEBBHNLP_02499 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEBBHNLP_02500 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
HEBBHNLP_02501 6.53e-121 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
HEBBHNLP_02502 1.45e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
HEBBHNLP_02503 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEBBHNLP_02504 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
HEBBHNLP_02505 1.35e-124 ywjB - - H - - - RibD C-terminal domain
HEBBHNLP_02506 1.32e-57 ywjC - - - - - - -
HEBBHNLP_02507 1.15e-234 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HEBBHNLP_02508 1.59e-285 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HEBBHNLP_02509 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
HEBBHNLP_02510 2.98e-269 acdA - - I - - - acyl-CoA dehydrogenase
HEBBHNLP_02511 2.07e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HEBBHNLP_02512 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HEBBHNLP_02513 6.41e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
HEBBHNLP_02514 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
HEBBHNLP_02515 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
HEBBHNLP_02516 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HEBBHNLP_02517 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEBBHNLP_02518 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
HEBBHNLP_02519 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HEBBHNLP_02520 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
HEBBHNLP_02521 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HEBBHNLP_02522 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
HEBBHNLP_02523 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
HEBBHNLP_02524 1.41e-115 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HEBBHNLP_02525 4.84e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEBBHNLP_02526 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HEBBHNLP_02527 5.71e-203 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HEBBHNLP_02529 5.61e-73 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HEBBHNLP_02530 1.14e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
HEBBHNLP_02531 1.63e-99 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
HEBBHNLP_02532 1.74e-249 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HEBBHNLP_02533 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
HEBBHNLP_02534 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEBBHNLP_02535 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
HEBBHNLP_02536 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
HEBBHNLP_02537 2.52e-302 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HEBBHNLP_02538 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HEBBHNLP_02539 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
HEBBHNLP_02540 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HEBBHNLP_02541 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEBBHNLP_02542 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HEBBHNLP_02543 7.94e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEBBHNLP_02544 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HEBBHNLP_02545 1.28e-194 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HEBBHNLP_02546 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HEBBHNLP_02547 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HEBBHNLP_02548 7.16e-114 ywmA - - - - - - -
HEBBHNLP_02549 4.54e-45 ywzB - - S - - - membrane
HEBBHNLP_02550 1.97e-173 ywmB - - S - - - TATA-box binding
HEBBHNLP_02551 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEBBHNLP_02552 1.69e-234 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
HEBBHNLP_02553 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HEBBHNLP_02554 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HEBBHNLP_02556 9.06e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HEBBHNLP_02557 6.25e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HEBBHNLP_02558 3.1e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HEBBHNLP_02560 7.7e-110 ywmF - - S - - - Peptidase M50
HEBBHNLP_02561 1.11e-21 csbD - - K - - - CsbD-like
HEBBHNLP_02562 6.86e-29 - - - E ko:K11963 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HEBBHNLP_02563 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
HEBBHNLP_02564 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
HEBBHNLP_02565 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HEBBHNLP_02566 4.58e-85 ywnA - - K - - - Transcriptional regulator
HEBBHNLP_02567 4.32e-147 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
HEBBHNLP_02568 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
HEBBHNLP_02569 4.85e-184 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
HEBBHNLP_02570 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEBBHNLP_02571 3.5e-90 ywnF - - S - - - Family of unknown function (DUF5392)
HEBBHNLP_02572 3.73e-241 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
HEBBHNLP_02573 8.74e-125 - - - J - - - Acetyltransferase (GNAT) domain
HEBBHNLP_02574 2.04e-236 spsG - - M - - - Spore Coat
HEBBHNLP_02575 4.19e-162 - - - M ko:K07257 - ko00000 Cytidylyltransferase
HEBBHNLP_02576 2.29e-274 pseC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
HEBBHNLP_02577 1.18e-224 - 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
HEBBHNLP_02578 4.68e-216 - - - M - - - GDP-mannose 4,6 dehydratase
HEBBHNLP_02579 1.16e-19 ywnC - - S - - - Family of unknown function (DUF5362)
HEBBHNLP_02580 1.81e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
HEBBHNLP_02581 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
HEBBHNLP_02582 1.63e-95 ywnJ - - S - - - VanZ like family
HEBBHNLP_02583 1.42e-133 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
HEBBHNLP_02584 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
HEBBHNLP_02585 1.6e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
HEBBHNLP_02586 5.04e-101 - - - - - - - -
HEBBHNLP_02587 1.48e-133 yjgF - - Q - - - Isochorismatase family
HEBBHNLP_02588 4.62e-308 ywoD - - EGP - - - Major facilitator superfamily
HEBBHNLP_02589 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
HEBBHNLP_02590 1.14e-309 ywoF - - P - - - Right handed beta helix region
HEBBHNLP_02591 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HEBBHNLP_02592 3.44e-91 - - - K - - - COG1846 Transcriptional regulators
HEBBHNLP_02593 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
HEBBHNLP_02594 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
HEBBHNLP_02595 7.2e-172 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
HEBBHNLP_02596 1.37e-180 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
HEBBHNLP_02597 1.5e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
HEBBHNLP_02598 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HEBBHNLP_02599 1.61e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HEBBHNLP_02600 0.0 ywpD - - T - - - Histidine kinase
HEBBHNLP_02601 4.13e-222 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
HEBBHNLP_02602 0.0 - - - M - - - cell wall anchor domain
HEBBHNLP_02603 8.3e-107 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HEBBHNLP_02604 8.81e-89 ywpF - - S - - - YwpF-like protein
HEBBHNLP_02605 5.26e-88 ywpG - - - - - - -
HEBBHNLP_02606 8.53e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
HEBBHNLP_02607 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HEBBHNLP_02608 3.06e-201 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HEBBHNLP_02609 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
HEBBHNLP_02610 0.0 ywqB - - S - - - SWIM zinc finger
HEBBHNLP_02611 3.6e-25 - - - - - - - -
HEBBHNLP_02612 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
HEBBHNLP_02613 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
HEBBHNLP_02614 2.39e-178 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
HEBBHNLP_02615 1.63e-313 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEBBHNLP_02616 1.71e-195 ywqG - - S - - - Domain of unknown function (DUF1963)
HEBBHNLP_02618 4.26e-51 ywqI - - S - - - Family of unknown function (DUF5344)
HEBBHNLP_02619 1.83e-313 ywqJ - - S - - - Pre-toxin TG
HEBBHNLP_02620 1.44e-82 - - - - - - - -
HEBBHNLP_02621 3.37e-126 - - - - - - - -
HEBBHNLP_02622 9.69e-95 - - - - - - - -
HEBBHNLP_02623 3.62e-156 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HEBBHNLP_02624 1.16e-209 - - - K - - - Transcriptional regulator
HEBBHNLP_02625 2.13e-129 ywqN - - S - - - NAD(P)H-dependent
HEBBHNLP_02627 7.09e-113 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
HEBBHNLP_02628 4.53e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
HEBBHNLP_02629 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
HEBBHNLP_02630 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
HEBBHNLP_02631 1.13e-70 - - - S - - - Domain of unknown function (DUF4181)
HEBBHNLP_02632 5.08e-142 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HEBBHNLP_02633 1.03e-17 - - - - - - - -
HEBBHNLP_02634 4.9e-264 cotH - - M ko:K06330 - ko00000 Spore Coat
HEBBHNLP_02635 1.06e-173 cotB - - - ko:K06325 - ko00000 -
HEBBHNLP_02636 2.14e-162 ywrJ - - - - - - -
HEBBHNLP_02637 3.25e-279 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HEBBHNLP_02638 3.36e-218 alsR - - K - - - LysR substrate binding domain
HEBBHNLP_02639 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HEBBHNLP_02640 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
HEBBHNLP_02641 3.57e-125 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
HEBBHNLP_02642 1.08e-62 ywsA - - S - - - Protein of unknown function (DUF3892)
HEBBHNLP_02643 4.83e-120 batE - - T - - - Sh3 type 3 domain protein
HEBBHNLP_02644 1.56e-204 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
HEBBHNLP_02645 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HEBBHNLP_02646 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HEBBHNLP_02647 6.55e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HEBBHNLP_02648 7.52e-206 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEBBHNLP_02649 2.68e-227 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
HEBBHNLP_02650 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
HEBBHNLP_02651 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
HEBBHNLP_02652 1.1e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HEBBHNLP_02653 2.29e-29 ywtC - - - - - - -
HEBBHNLP_02654 1.12e-303 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HEBBHNLP_02655 3.08e-58 orfX1 - - L - - - Transposase
HEBBHNLP_02656 2.28e-172 - - - L - - - Integrase core domain
HEBBHNLP_02657 1.2e-203 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HEBBHNLP_02658 1.67e-176 ywtF_2 - - K - - - Transcriptional regulator
HEBBHNLP_02659 5.27e-314 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEBBHNLP_02660 3.29e-259 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
HEBBHNLP_02661 2.45e-247 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
HEBBHNLP_02662 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HEBBHNLP_02663 3.57e-236 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HEBBHNLP_02664 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEBBHNLP_02665 6.69e-158 - - - M - - - Glycosyl transferase group 1 protein
HEBBHNLP_02666 3.19e-199 - - - M - - - Glycosyl transferases group 1
HEBBHNLP_02668 1.32e-146 - - - M - - - DUF based on E. rectale Gene description (DUF3880)
HEBBHNLP_02669 1.62e-199 capO 1.1.1.336 - M ko:K02472 ko00520,ko05111,map00520,map05111 ko00000,ko00001,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEBBHNLP_02670 1.63e-151 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEBBHNLP_02671 6.01e-36 - - - S - - - alpha beta
HEBBHNLP_02672 4.39e-136 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEBBHNLP_02673 5.94e-111 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HEBBHNLP_02674 5.17e-71 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
HEBBHNLP_02675 3.64e-172 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEBBHNLP_02676 1.91e-239 - - - M - - - Glycosyltransferase like family 2
HEBBHNLP_02677 0.0 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HEBBHNLP_02678 1.08e-164 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
HEBBHNLP_02679 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HEBBHNLP_02680 4.76e-27 - - - L - - - Integrase core domain
HEBBHNLP_02681 3.2e-207 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HEBBHNLP_02682 2.37e-271 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HEBBHNLP_02683 3.41e-204 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HEBBHNLP_02685 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HEBBHNLP_02686 6.88e-316 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEBBHNLP_02687 3.42e-280 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
HEBBHNLP_02688 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEBBHNLP_02689 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
HEBBHNLP_02690 2.02e-147 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
HEBBHNLP_02691 6.92e-186 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
HEBBHNLP_02692 1.18e-296 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
HEBBHNLP_02693 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HEBBHNLP_02694 9.37e-224 yvhJ - - K - - - Transcriptional regulator
HEBBHNLP_02695 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
HEBBHNLP_02696 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HEBBHNLP_02697 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEBBHNLP_02698 1.77e-198 degV - - S - - - protein conserved in bacteria
HEBBHNLP_02699 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HEBBHNLP_02700 4.22e-60 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
HEBBHNLP_02701 2.26e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
HEBBHNLP_02702 1.83e-96 yvyF - - S - - - flagellar protein
HEBBHNLP_02703 8.72e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
HEBBHNLP_02704 3.5e-102 yvyG - - NOU - - - FlgN protein
HEBBHNLP_02705 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
HEBBHNLP_02706 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
HEBBHNLP_02707 1.7e-92 yviE - - - - - - -
HEBBHNLP_02708 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HEBBHNLP_02709 3.02e-40 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HEBBHNLP_02710 1.43e-124 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HEBBHNLP_02711 1.1e-76 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
HEBBHNLP_02712 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HEBBHNLP_02713 5.15e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
HEBBHNLP_02714 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
HEBBHNLP_02715 7.52e-87 - - - - - - - -
HEBBHNLP_02716 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HEBBHNLP_02717 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HEBBHNLP_02718 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HEBBHNLP_02719 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HEBBHNLP_02720 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
HEBBHNLP_02721 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
HEBBHNLP_02722 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HEBBHNLP_02723 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HEBBHNLP_02724 1.38e-73 swrA - - S - - - Swarming motility protein
HEBBHNLP_02725 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEBBHNLP_02726 5.01e-294 yvkA - - P - - - -transporter
HEBBHNLP_02727 1.43e-131 yvkB - - K - - - Transcriptional regulator
HEBBHNLP_02728 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
HEBBHNLP_02729 2.54e-42 csbA - - S - - - protein conserved in bacteria
HEBBHNLP_02730 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HEBBHNLP_02731 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HEBBHNLP_02732 1.68e-157 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HEBBHNLP_02733 2.25e-45 yvkN - - - - - - -
HEBBHNLP_02734 1.34e-63 yvlA - - - - - - -
HEBBHNLP_02735 9.59e-220 yvlB - - S - - - Putative adhesin
HEBBHNLP_02736 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
HEBBHNLP_02737 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
HEBBHNLP_02738 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
HEBBHNLP_02739 1.44e-169 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
HEBBHNLP_02740 2.58e-167 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEBBHNLP_02741 1.39e-278 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HEBBHNLP_02742 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HEBBHNLP_02743 2.15e-193 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HEBBHNLP_02744 1.45e-208 yvoD - - P - - - COG0370 Fe2 transport system protein B
HEBBHNLP_02745 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HEBBHNLP_02746 2.07e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HEBBHNLP_02747 3.83e-154 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
HEBBHNLP_02748 2.58e-175 yvpB - - NU - - - protein conserved in bacteria
HEBBHNLP_02749 9.84e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HEBBHNLP_02750 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HEBBHNLP_02751 8.99e-293 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HEBBHNLP_02752 2.87e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
HEBBHNLP_02753 1.34e-145 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HEBBHNLP_02754 6.28e-165 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HEBBHNLP_02755 9.34e-175 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HEBBHNLP_02756 1.7e-142 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
HEBBHNLP_02757 6.36e-172 - - - - - - - -
HEBBHNLP_02758 0.0 - - - - - - - -
HEBBHNLP_02760 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HEBBHNLP_02761 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
HEBBHNLP_02762 2.2e-179 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
HEBBHNLP_02763 1.18e-225 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HEBBHNLP_02764 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HEBBHNLP_02765 8.53e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HEBBHNLP_02766 3.88e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HEBBHNLP_02767 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HEBBHNLP_02768 1.6e-49 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
HEBBHNLP_02769 1.62e-182 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
HEBBHNLP_02770 5.4e-43 - - - - - - - -
HEBBHNLP_02771 3.84e-171 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBBHNLP_02772 1.68e-252 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
HEBBHNLP_02773 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HEBBHNLP_02774 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
HEBBHNLP_02775 2.7e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEBBHNLP_02776 8.79e-136 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HEBBHNLP_02777 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
HEBBHNLP_02778 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
HEBBHNLP_02779 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HEBBHNLP_02780 1.54e-221 yvdE - - K - - - Transcriptional regulator
HEBBHNLP_02781 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
HEBBHNLP_02782 1.2e-301 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
HEBBHNLP_02783 6.09e-311 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
HEBBHNLP_02784 1.96e-189 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
HEBBHNLP_02785 6.37e-199 malA - - S - - - Protein of unknown function (DUF1189)
HEBBHNLP_02786 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
HEBBHNLP_02787 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HEBBHNLP_02788 3.76e-147 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HEBBHNLP_02789 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HEBBHNLP_02791 1.12e-121 yvdQ - - S - - - Protein of unknown function (DUF3231)
HEBBHNLP_02792 1.47e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
HEBBHNLP_02793 2.57e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HEBBHNLP_02794 3.22e-135 yvdT_1 - - K - - - Transcriptional regulator
HEBBHNLP_02795 0.0 ybeC - - E - - - amino acid
HEBBHNLP_02796 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HEBBHNLP_02797 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
HEBBHNLP_02798 7.19e-86 - - - - - - - -
HEBBHNLP_02799 0.0 pbpE - - V - - - Beta-lactamase
HEBBHNLP_02800 6.14e-163 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HEBBHNLP_02801 1.1e-96 - - - S - - - Protein of unknown function (DUF3237)
HEBBHNLP_02802 3.13e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
HEBBHNLP_02804 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
HEBBHNLP_02805 1.24e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
HEBBHNLP_02806 1.61e-157 epsA - - M ko:K19420 - ko00000 biosynthesis protein
HEBBHNLP_02807 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
HEBBHNLP_02808 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
HEBBHNLP_02809 7.45e-280 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
HEBBHNLP_02810 1.25e-201 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
HEBBHNLP_02811 8.38e-277 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HEBBHNLP_02812 8.82e-265 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
HEBBHNLP_02813 6.76e-246 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
HEBBHNLP_02814 5.47e-259 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
HEBBHNLP_02815 1.17e-246 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HEBBHNLP_02816 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEBBHNLP_02817 3.19e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HEBBHNLP_02818 1.43e-77 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HEBBHNLP_02819 2.39e-275 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
HEBBHNLP_02820 2.71e-234 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
HEBBHNLP_02821 5.69e-44 yvfG - - S - - - YvfG protein
HEBBHNLP_02822 6.75e-304 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HEBBHNLP_02823 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HEBBHNLP_02824 2.79e-145 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
HEBBHNLP_02825 1.15e-235 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HEBBHNLP_02826 1.48e-288 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
HEBBHNLP_02827 1.77e-299 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
HEBBHNLP_02828 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
HEBBHNLP_02829 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
HEBBHNLP_02830 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
HEBBHNLP_02831 1.02e-263 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
HEBBHNLP_02832 5.96e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
HEBBHNLP_02833 1.15e-66 - - - S - - - ASCH
HEBBHNLP_02834 4.59e-178 - - - M - - - -acetyltransferase
HEBBHNLP_02835 5.84e-33 - 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 AAA domain
HEBBHNLP_02836 1.79e-194 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
HEBBHNLP_02837 2.04e-170 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
HEBBHNLP_02838 2.98e-249 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEBBHNLP_02839 3.58e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEBBHNLP_02840 4.23e-42 - - - K - - - Transcriptional regulator PadR-like family
HEBBHNLP_02841 3.88e-57 - - - S - - - Protein of unknown function (DUF2812)
HEBBHNLP_02842 1.06e-173 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HEBBHNLP_02843 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HEBBHNLP_02844 2.8e-170 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HEBBHNLP_02845 3.35e-246 - - - S - - - Glycosyl hydrolase
HEBBHNLP_02846 1.66e-305 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HEBBHNLP_02847 4.59e-197 yvbV - - EG - - - EamA-like transporter family
HEBBHNLP_02848 4.9e-206 yvbU - - K - - - Transcriptional regulator
HEBBHNLP_02849 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEBBHNLP_02850 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
HEBBHNLP_02851 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEBBHNLP_02852 5.69e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HEBBHNLP_02853 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEBBHNLP_02854 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HEBBHNLP_02855 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEBBHNLP_02856 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
HEBBHNLP_02857 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEBBHNLP_02858 2.8e-105 yvbK - - K - - - acetyltransferase
HEBBHNLP_02859 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HEBBHNLP_02860 9.3e-156 yvbI - - M - - - Membrane
HEBBHNLP_02861 1.2e-144 yvbH - - S - - - YvbH-like oligomerisation region
HEBBHNLP_02862 7.95e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
HEBBHNLP_02863 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
HEBBHNLP_02864 1.13e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HEBBHNLP_02865 2.29e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HEBBHNLP_02866 8.64e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEBBHNLP_02867 9.67e-137 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HEBBHNLP_02868 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
HEBBHNLP_02869 3.49e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HEBBHNLP_02870 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HEBBHNLP_02871 4.78e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEBBHNLP_02872 2.89e-133 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HEBBHNLP_02873 7.33e-233 - - - S - - - Lantibiotic dehydratase, C terminus
HEBBHNLP_02874 3.45e-192 - - - V ko:K06147,ko:K06148,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC transporter
HEBBHNLP_02875 2.35e-97 spaC1 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C-like protein
HEBBHNLP_02878 7.1e-131 spaF - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HEBBHNLP_02879 3.36e-110 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HEBBHNLP_02880 1.49e-103 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HEBBHNLP_02881 1.41e-135 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
HEBBHNLP_02882 7.24e-195 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
HEBBHNLP_02883 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HEBBHNLP_02884 3.85e-72 yvaP - - K - - - transcriptional
HEBBHNLP_02885 1.34e-89 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HEBBHNLP_02886 3.5e-89 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
HEBBHNLP_02887 4.9e-48 yvzC - - K - - - transcriptional
HEBBHNLP_02888 2.73e-194 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
HEBBHNLP_02889 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
HEBBHNLP_02890 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
HEBBHNLP_02891 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HEBBHNLP_02892 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HEBBHNLP_02894 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBBHNLP_02895 5.77e-127 - - - K - - - Bacterial regulatory proteins, tetR family
HEBBHNLP_02896 3.52e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
HEBBHNLP_02897 2.02e-97 yvaD - - S - - - Family of unknown function (DUF5360)
HEBBHNLP_02898 0.0 - - - S - - - Fusaric acid resistance protein-like
HEBBHNLP_02899 2.08e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEBBHNLP_02900 3.3e-246 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HEBBHNLP_02901 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
HEBBHNLP_02902 3.66e-41 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
HEBBHNLP_02903 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HEBBHNLP_02904 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
HEBBHNLP_02905 6.66e-135 bdbD - - O - - - Thioredoxin
HEBBHNLP_02906 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
HEBBHNLP_02907 2.34e-139 yvgT - - S - - - membrane
HEBBHNLP_02909 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HEBBHNLP_02910 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HEBBHNLP_02911 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HEBBHNLP_02912 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
HEBBHNLP_02913 7.97e-113 yvgO - - - - - - -
HEBBHNLP_02914 6.19e-201 yvgN - - S - - - reductase
HEBBHNLP_02915 4.1e-152 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
HEBBHNLP_02916 6.03e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
HEBBHNLP_02917 1.03e-213 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
HEBBHNLP_02918 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
HEBBHNLP_02919 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
HEBBHNLP_02920 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
HEBBHNLP_02921 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HEBBHNLP_02922 3.13e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEBBHNLP_02923 4.93e-236 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBBHNLP_02924 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBBHNLP_02925 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HEBBHNLP_02926 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
HEBBHNLP_02927 1.89e-158 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEBBHNLP_02928 3.13e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HEBBHNLP_02929 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
HEBBHNLP_02930 8.85e-290 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
HEBBHNLP_02931 5.71e-25 - - - S - - - YvrJ protein family
HEBBHNLP_02932 4.23e-125 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
HEBBHNLP_02933 6.16e-33 - - - - - - - -
HEBBHNLP_02934 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBBHNLP_02935 0.0 yvrG - - T - - - Histidine kinase
HEBBHNLP_02936 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
HEBBHNLP_02937 4.99e-180 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBBHNLP_02938 2.1e-218 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HEBBHNLP_02939 9.02e-235 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBBHNLP_02940 1.05e-308 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HEBBHNLP_02941 4.37e-128 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
HEBBHNLP_02942 1.13e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HEBBHNLP_02943 3.57e-81 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
HEBBHNLP_02944 2.44e-143 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HEBBHNLP_02945 7.32e-175 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
HEBBHNLP_02946 7.65e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
HEBBHNLP_02947 3.72e-242 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEBBHNLP_02948 4.46e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEBBHNLP_02949 3.05e-243 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
HEBBHNLP_02950 3.94e-251 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
HEBBHNLP_02951 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HEBBHNLP_02952 2.6e-33 - - - S - - - Protein of unknown function (DUF3970)
HEBBHNLP_02953 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HEBBHNLP_02954 3.06e-204 yuxN - - K - - - Transcriptional regulator
HEBBHNLP_02955 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEBBHNLP_02956 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBBHNLP_02957 1.12e-304 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEBBHNLP_02958 2.15e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
HEBBHNLP_02959 1.23e-193 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBBHNLP_02960 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
HEBBHNLP_02961 3.48e-88 - - - S - - - YusW-like protein
HEBBHNLP_02962 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HEBBHNLP_02963 3.99e-53 yusU - - S - - - Protein of unknown function (DUF2573)
HEBBHNLP_02964 1.98e-202 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
HEBBHNLP_02965 7.05e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBBHNLP_02966 4.86e-84 yusQ - - S - - - Tautomerase enzyme
HEBBHNLP_02967 0.0 yusP - - P - - - Major facilitator superfamily
HEBBHNLP_02968 3.67e-97 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
HEBBHNLP_02969 8.66e-70 yusN - - M - - - Coat F domain
HEBBHNLP_02970 4.51e-54 - - - - - - - -
HEBBHNLP_02971 2.84e-210 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
HEBBHNLP_02972 1.11e-13 - - - S - - - YuzL-like protein
HEBBHNLP_02973 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
HEBBHNLP_02974 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
HEBBHNLP_02975 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
HEBBHNLP_02976 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
HEBBHNLP_02977 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HEBBHNLP_02978 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
HEBBHNLP_02979 2.18e-96 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
HEBBHNLP_02980 2e-73 yusE - - CO - - - Thioredoxin
HEBBHNLP_02981 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
HEBBHNLP_02982 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HEBBHNLP_02983 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
HEBBHNLP_02984 5.86e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
HEBBHNLP_02985 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HEBBHNLP_02986 4.46e-182 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HEBBHNLP_02987 6.1e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
HEBBHNLP_02988 7.72e-297 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HEBBHNLP_02989 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
HEBBHNLP_02990 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
HEBBHNLP_02991 2.93e-85 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEBBHNLP_02992 3.35e-56 - - - - - - - -
HEBBHNLP_02994 1.93e-266 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
HEBBHNLP_02995 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
HEBBHNLP_02996 5.27e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HEBBHNLP_02997 4.07e-307 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
HEBBHNLP_02998 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEBBHNLP_02999 1.94e-216 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HEBBHNLP_03000 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
HEBBHNLP_03001 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
HEBBHNLP_03002 2.42e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEBBHNLP_03003 6.27e-216 bsn - - L - - - Ribonuclease
HEBBHNLP_03004 1.18e-294 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HEBBHNLP_03005 4.04e-304 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HEBBHNLP_03006 1.02e-233 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HEBBHNLP_03007 2.52e-142 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
HEBBHNLP_03008 7.39e-189 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HEBBHNLP_03009 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HEBBHNLP_03010 8.11e-121 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HEBBHNLP_03011 0.000108 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HEBBHNLP_03012 4.38e-74 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HEBBHNLP_03013 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HEBBHNLP_03014 2.61e-282 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
HEBBHNLP_03015 2.58e-294 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
HEBBHNLP_03016 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
HEBBHNLP_03017 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HEBBHNLP_03018 3.06e-79 yunG - - - - - - -
HEBBHNLP_03019 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
HEBBHNLP_03020 5.34e-180 yunE - - S ko:K07090 - ko00000 membrane transporter protein
HEBBHNLP_03021 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HEBBHNLP_03022 5.67e-64 yunC - - S - - - Domain of unknown function (DUF1805)
HEBBHNLP_03023 3.49e-169 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
HEBBHNLP_03024 7.63e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
HEBBHNLP_03025 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HEBBHNLP_03026 1.34e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEBBHNLP_03027 3.2e-63 yutD - - S - - - protein conserved in bacteria
HEBBHNLP_03028 1.96e-98 yutE - - S - - - Protein of unknown function DUF86
HEBBHNLP_03029 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HEBBHNLP_03030 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
HEBBHNLP_03031 4.98e-252 yutH - - S - - - Spore coat protein
HEBBHNLP_03032 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HEBBHNLP_03033 6.87e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HEBBHNLP_03034 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HEBBHNLP_03035 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
HEBBHNLP_03036 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
HEBBHNLP_03037 2.7e-74 yuzD - - S - - - protein conserved in bacteria
HEBBHNLP_03038 2.63e-252 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HEBBHNLP_03039 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
HEBBHNLP_03040 3.61e-269 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEBBHNLP_03041 1.12e-207 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HEBBHNLP_03042 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
HEBBHNLP_03043 1.62e-114 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEBBHNLP_03044 8.15e-149 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
HEBBHNLP_03045 1.06e-233 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEBBHNLP_03047 3.88e-239 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
HEBBHNLP_03048 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HEBBHNLP_03049 1.14e-45 yuiB - - S - - - Putative membrane protein
HEBBHNLP_03050 2.69e-150 yuiC - - S - - - protein conserved in bacteria
HEBBHNLP_03051 1.95e-98 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
HEBBHNLP_03052 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HEBBHNLP_03053 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
HEBBHNLP_03054 3.95e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
HEBBHNLP_03055 1.37e-156 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
HEBBHNLP_03056 8.94e-213 eSD - - S ko:K07017 - ko00000 Putative esterase
HEBBHNLP_03057 3.37e-177 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBBHNLP_03058 1.22e-289 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
HEBBHNLP_03059 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
HEBBHNLP_03060 3.15e-228 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
HEBBHNLP_03061 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBBHNLP_03062 2.02e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
HEBBHNLP_03063 6.94e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
HEBBHNLP_03064 1.64e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
HEBBHNLP_03065 6.39e-287 yukF - - QT - - - Transcriptional regulator
HEBBHNLP_03066 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
HEBBHNLP_03067 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
HEBBHNLP_03068 1.43e-269 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
HEBBHNLP_03069 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HEBBHNLP_03070 0.0 yueB - - S - - - type VII secretion protein EsaA
HEBBHNLP_03071 5.1e-96 yueC - - S - - - Family of unknown function (DUF5383)
HEBBHNLP_03072 3.53e-170 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBBHNLP_03073 7.78e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
HEBBHNLP_03074 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
HEBBHNLP_03075 1.85e-06 - - - S - - - Protein of unknown function (DUF2283)
HEBBHNLP_03076 3.87e-244 yueF - - S - - - transporter activity
HEBBHNLP_03077 1.19e-41 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
HEBBHNLP_03078 1.63e-52 yueH - - S - - - YueH-like protein
HEBBHNLP_03079 8.92e-87 - - - S - - - Protein of unknown function (DUF1694)
HEBBHNLP_03080 2.69e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
HEBBHNLP_03081 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEBBHNLP_03082 9.77e-297 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
HEBBHNLP_03083 4.38e-09 yuzC - - - - - - -
HEBBHNLP_03084 6.29e-10 - - - S - - - DegQ (SacQ) family
HEBBHNLP_03085 1.15e-192 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
HEBBHNLP_03087 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEBBHNLP_03088 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEBBHNLP_03089 7.81e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
HEBBHNLP_03090 8.49e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
HEBBHNLP_03091 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEBBHNLP_03092 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEBBHNLP_03093 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEBBHNLP_03094 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEBBHNLP_03095 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEBBHNLP_03096 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HEBBHNLP_03097 1.73e-22 - - - - - - - -
HEBBHNLP_03098 7.99e-309 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
HEBBHNLP_03099 2.43e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HEBBHNLP_03100 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HEBBHNLP_03101 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEBBHNLP_03102 1.28e-253 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
HEBBHNLP_03103 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
HEBBHNLP_03104 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HEBBHNLP_03105 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
HEBBHNLP_03106 1.85e-95 yuxK - - S - - - protein conserved in bacteria
HEBBHNLP_03107 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
HEBBHNLP_03108 1.08e-242 yuxJ - - EGP - - - Major facilitator superfamily
HEBBHNLP_03110 1.71e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
HEBBHNLP_03111 2.49e-91 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
HEBBHNLP_03112 3.04e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEBBHNLP_03113 9.52e-286 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HEBBHNLP_03114 1.58e-54 yugE - - S - - - Domain of unknown function (DUF1871)
HEBBHNLP_03115 1.71e-201 yugF - - I - - - Hydrolase
HEBBHNLP_03116 6.74e-112 alaR - - K - - - Transcriptional regulator
HEBBHNLP_03117 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
HEBBHNLP_03118 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
HEBBHNLP_03119 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
HEBBHNLP_03120 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
HEBBHNLP_03121 3.76e-289 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
HEBBHNLP_03122 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HEBBHNLP_03124 4.22e-95 yugN - - S - - - YugN-like family
HEBBHNLP_03125 3.56e-233 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
HEBBHNLP_03126 5.01e-69 mstX - - S - - - Membrane-integrating protein Mistic
HEBBHNLP_03127 1.58e-50 - - - - - - - -
HEBBHNLP_03128 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
HEBBHNLP_03129 5.09e-300 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HEBBHNLP_03130 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HEBBHNLP_03131 1.48e-94 yugU - - S - - - Uncharacterised protein family UPF0047
HEBBHNLP_03132 5e-48 - - - - - - - -
HEBBHNLP_03133 1.45e-179 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HEBBHNLP_03134 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HEBBHNLP_03135 1.81e-299 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HEBBHNLP_03136 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HEBBHNLP_03137 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HEBBHNLP_03138 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
HEBBHNLP_03139 2.02e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HEBBHNLP_03140 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HEBBHNLP_03141 3.35e-71 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
HEBBHNLP_03142 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
HEBBHNLP_03143 3.71e-235 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HEBBHNLP_03144 8.95e-255 yubA - - S - - - transporter activity
HEBBHNLP_03145 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HEBBHNLP_03147 2.29e-112 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
HEBBHNLP_03148 0.0 yubD - - P - - - Major Facilitator Superfamily
HEBBHNLP_03152 6.38e-197 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEBBHNLP_03153 3.31e-52 yubF - - S - - - yiaA/B two helix domain
HEBBHNLP_03154 5.29e-276 - - - P ko:K03498 - ko00000,ko02000 Potassium
HEBBHNLP_03155 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
HEBBHNLP_03156 5.83e-118 yuaB - - - - - - -
HEBBHNLP_03157 3.39e-121 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
HEBBHNLP_03158 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HEBBHNLP_03159 1e-290 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
HEBBHNLP_03160 5.57e-135 yuaD - - - - - - -
HEBBHNLP_03161 1.95e-109 yuaE - - S - - - DinB superfamily
HEBBHNLP_03162 1.68e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
HEBBHNLP_03163 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
HEBBHNLP_03164 3.44e-122 - - - M - - - FR47-like protein
HEBBHNLP_03165 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
HEBBHNLP_03166 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HEBBHNLP_03188 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HEBBHNLP_03189 2.43e-264 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HEBBHNLP_03190 3.72e-238 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
HEBBHNLP_03191 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
HEBBHNLP_03192 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HEBBHNLP_03193 5.66e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
HEBBHNLP_03194 6.11e-259 cotI - - S ko:K06331 - ko00000 Spore coat protein
HEBBHNLP_03195 1.75e-276 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
HEBBHNLP_03196 6.65e-261 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
HEBBHNLP_03198 3.4e-296 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
HEBBHNLP_03199 4.3e-228 ytcB - - M - - - NAD-dependent epimerase dehydratase
HEBBHNLP_03200 2.27e-307 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEBBHNLP_03201 6.65e-194 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
HEBBHNLP_03202 8.68e-169 yteA - - T - - - COG1734 DnaK suppressor protein
HEBBHNLP_03203 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
HEBBHNLP_03204 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HEBBHNLP_03205 5.46e-194 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HEBBHNLP_03206 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HEBBHNLP_03207 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HEBBHNLP_03208 2.37e-271 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HEBBHNLP_03209 3.1e-216 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HEBBHNLP_03210 2.79e-175 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HEBBHNLP_03211 2.49e-294 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HEBBHNLP_03212 9.24e-192 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HEBBHNLP_03213 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
HEBBHNLP_03214 1.64e-238 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HEBBHNLP_03215 1.5e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
HEBBHNLP_03216 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HEBBHNLP_03217 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HEBBHNLP_03218 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HEBBHNLP_03219 4.78e-95 ytkA - - S - - - YtkA-like
HEBBHNLP_03221 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HEBBHNLP_03222 3.2e-81 ytkC - - S - - - Bacteriophage holin family
HEBBHNLP_03223 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HEBBHNLP_03224 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HEBBHNLP_03225 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HEBBHNLP_03226 2.66e-240 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HEBBHNLP_03227 3.86e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HEBBHNLP_03228 3.33e-51 ytmB - - S - - - Protein of unknown function (DUF2584)
HEBBHNLP_03229 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HEBBHNLP_03230 9.2e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HEBBHNLP_03231 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HEBBHNLP_03232 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HEBBHNLP_03233 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HEBBHNLP_03234 4.7e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
HEBBHNLP_03235 4.81e-276 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
HEBBHNLP_03236 3.91e-136 ytqB - - J - - - Putative rRNA methylase
HEBBHNLP_03237 9.56e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
HEBBHNLP_03238 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
HEBBHNLP_03240 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
HEBBHNLP_03241 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HEBBHNLP_03242 6.67e-190 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HEBBHNLP_03243 1.9e-162 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
HEBBHNLP_03244 5.88e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HEBBHNLP_03245 9.81e-297 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HEBBHNLP_03246 9.07e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBBHNLP_03247 8.77e-237 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
HEBBHNLP_03248 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
HEBBHNLP_03249 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
HEBBHNLP_03250 2.32e-77 yttA - - S - - - Pfam Transposase IS66
HEBBHNLP_03251 6.01e-269 yttB - - EGP - - - Major facilitator superfamily
HEBBHNLP_03252 9e-182 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HEBBHNLP_03253 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
HEBBHNLP_03254 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HEBBHNLP_03255 1.22e-68 ytwF - - P - - - Sulfurtransferase
HEBBHNLP_03256 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HEBBHNLP_03257 6.29e-185 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
HEBBHNLP_03258 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEBBHNLP_03259 4.27e-311 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HEBBHNLP_03260 1.46e-240 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HEBBHNLP_03261 1.95e-220 - - - S - - - Acetyl xylan esterase (AXE1)
HEBBHNLP_03262 3.57e-176 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HEBBHNLP_03263 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HEBBHNLP_03264 1.49e-274 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HEBBHNLP_03265 1.55e-158 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HEBBHNLP_03266 2.64e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HEBBHNLP_03267 2.13e-277 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HEBBHNLP_03268 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
HEBBHNLP_03269 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HEBBHNLP_03270 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
HEBBHNLP_03271 0.0 ytdP - - K - - - Transcriptional regulator
HEBBHNLP_03272 1.31e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
HEBBHNLP_03273 3.11e-274 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HEBBHNLP_03274 1.6e-92 yteS - - G - - - transport
HEBBHNLP_03275 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HEBBHNLP_03276 8.98e-149 yteU - - S - - - Integral membrane protein
HEBBHNLP_03277 2.14e-36 yteV - - S - - - Sporulation protein Cse60
HEBBHNLP_03278 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
HEBBHNLP_03279 4.04e-293 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
HEBBHNLP_03280 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEBBHNLP_03281 2.13e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HEBBHNLP_03282 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
HEBBHNLP_03283 5.66e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HEBBHNLP_03284 1.67e-253 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
HEBBHNLP_03285 1.73e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
HEBBHNLP_03286 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
HEBBHNLP_03287 8.59e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HEBBHNLP_03288 2.13e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HEBBHNLP_03289 4.92e-212 ytlQ - - - - - - -
HEBBHNLP_03290 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HEBBHNLP_03291 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HEBBHNLP_03292 8.67e-192 ytmP - - M - - - Phosphotransferase
HEBBHNLP_03293 9.51e-61 ytzH - - S - - - YtzH-like protein
HEBBHNLP_03294 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HEBBHNLP_03295 1.06e-190 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HEBBHNLP_03296 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
HEBBHNLP_03297 1.17e-67 ytzB - - S - - - small secreted protein
HEBBHNLP_03298 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
HEBBHNLP_03299 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
HEBBHNLP_03300 3.17e-75 ytpP - - CO - - - Thioredoxin
HEBBHNLP_03301 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
HEBBHNLP_03302 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEBBHNLP_03303 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HEBBHNLP_03304 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HEBBHNLP_03305 3.21e-60 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HEBBHNLP_03306 8.99e-30 ytxH - - S - - - COG4980 Gas vesicle protein
HEBBHNLP_03307 1.57e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
HEBBHNLP_03308 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HEBBHNLP_03309 1.7e-234 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HEBBHNLP_03310 6.84e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
HEBBHNLP_03311 1.91e-156 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
HEBBHNLP_03312 4.4e-291 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
HEBBHNLP_03313 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
HEBBHNLP_03314 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HEBBHNLP_03315 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HEBBHNLP_03316 5.31e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEBBHNLP_03318 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HEBBHNLP_03319 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
HEBBHNLP_03320 1.13e-113 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HEBBHNLP_03321 1.2e-141 yttP - - K - - - Transcriptional regulator
HEBBHNLP_03322 1.25e-196 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HEBBHNLP_03323 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HEBBHNLP_03324 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HEBBHNLP_03325 3.9e-266 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HEBBHNLP_03326 3.62e-288 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEBBHNLP_03327 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
HEBBHNLP_03328 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HEBBHNLP_03329 0.0 ytcJ - - S - - - amidohydrolase
HEBBHNLP_03330 1.39e-188 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEBBHNLP_03331 9.73e-230 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
HEBBHNLP_03332 4.08e-112 yteJ - - S - - - RDD family
HEBBHNLP_03333 2.39e-148 ytfI - - S - - - Protein of unknown function (DUF2953)
HEBBHNLP_03334 1.06e-94 ytfJ - - S - - - Sporulation protein YtfJ
HEBBHNLP_03335 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HEBBHNLP_03336 3.78e-224 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
HEBBHNLP_03337 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEBBHNLP_03338 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
HEBBHNLP_03339 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HEBBHNLP_03340 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HEBBHNLP_03342 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBBHNLP_03343 5.47e-166 ytkL - - S - - - Belongs to the UPF0173 family
HEBBHNLP_03344 3.93e-220 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
HEBBHNLP_03345 1.98e-128 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HEBBHNLP_03346 5.9e-191 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HEBBHNLP_03347 1.57e-191 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HEBBHNLP_03348 1.36e-156 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEBBHNLP_03349 6.48e-153 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEBBHNLP_03350 1.56e-181 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HEBBHNLP_03351 2.51e-236 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEBBHNLP_03352 4.79e-23 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
HEBBHNLP_03353 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEBBHNLP_03354 2.81e-165 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
HEBBHNLP_03355 1.84e-300 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
HEBBHNLP_03356 3.71e-205 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
HEBBHNLP_03357 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
HEBBHNLP_03358 2.15e-63 ytpI - - S - - - YtpI-like protein
HEBBHNLP_03359 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
HEBBHNLP_03360 1.15e-39 - - - - - - - -
HEBBHNLP_03361 5.12e-112 ytrI - - - - - - -
HEBBHNLP_03362 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
HEBBHNLP_03363 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HEBBHNLP_03364 1.41e-285 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
HEBBHNLP_03365 1.25e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HEBBHNLP_03366 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HEBBHNLP_03367 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HEBBHNLP_03368 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HEBBHNLP_03369 4.68e-82 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
HEBBHNLP_03370 2.73e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
HEBBHNLP_03371 9.38e-95 ytwI - - S - - - membrane
HEBBHNLP_03372 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HEBBHNLP_03373 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
HEBBHNLP_03374 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
HEBBHNLP_03375 3.27e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBBHNLP_03376 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
HEBBHNLP_03377 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEBBHNLP_03378 4.05e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HEBBHNLP_03379 9.74e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
HEBBHNLP_03380 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HEBBHNLP_03381 4.54e-205 ytbE - - S - - - reductase
HEBBHNLP_03382 5.2e-258 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
HEBBHNLP_03383 9.85e-88 ytcD - - K - - - Transcriptional regulator
HEBBHNLP_03384 2.02e-245 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEBBHNLP_03385 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HEBBHNLP_03386 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HEBBHNLP_03387 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
HEBBHNLP_03388 1e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HEBBHNLP_03389 5.65e-143 ytxB - - S - - - SNARE associated Golgi protein
HEBBHNLP_03390 3.46e-205 ytxC - - S - - - YtxC-like family
HEBBHNLP_03392 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEBBHNLP_03393 2.32e-188 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
HEBBHNLP_03394 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEBBHNLP_03395 1.96e-166 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
HEBBHNLP_03396 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HEBBHNLP_03397 1.53e-149 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HEBBHNLP_03399 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HEBBHNLP_03400 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HEBBHNLP_03401 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HEBBHNLP_03402 1.27e-59 ysdA - - S - - - Membrane
HEBBHNLP_03403 2.29e-88 ysdB - - S - - - Sigma-w pathway protein YsdB
HEBBHNLP_03404 1.77e-261 ysdC - - G - - - COG1363 Cellulase M and related proteins
HEBBHNLP_03405 9.92e-242 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
HEBBHNLP_03406 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
HEBBHNLP_03407 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
HEBBHNLP_03408 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HEBBHNLP_03409 1e-185 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
HEBBHNLP_03410 4.72e-285 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HEBBHNLP_03411 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
HEBBHNLP_03412 6.77e-219 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
HEBBHNLP_03413 2.12e-190 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
HEBBHNLP_03414 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
HEBBHNLP_03415 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
HEBBHNLP_03416 1.79e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
HEBBHNLP_03417 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
HEBBHNLP_03418 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
HEBBHNLP_03419 7.2e-260 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
HEBBHNLP_03420 4.37e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
HEBBHNLP_03421 7.37e-170 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEBBHNLP_03422 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HEBBHNLP_03423 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEBBHNLP_03424 8.48e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEBBHNLP_03425 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HEBBHNLP_03426 3.12e-111 yshB - - S - - - membrane protein, required for colicin V production
HEBBHNLP_03427 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
HEBBHNLP_03428 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HEBBHNLP_03429 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
HEBBHNLP_03430 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HEBBHNLP_03431 5.74e-129 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
HEBBHNLP_03432 3.12e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
HEBBHNLP_03433 1.05e-178 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
HEBBHNLP_03434 2.04e-226 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
HEBBHNLP_03436 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
HEBBHNLP_03437 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HEBBHNLP_03438 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HEBBHNLP_03439 1.61e-274 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HEBBHNLP_03440 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
HEBBHNLP_03441 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
HEBBHNLP_03442 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
HEBBHNLP_03443 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
HEBBHNLP_03444 5.35e-102 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
HEBBHNLP_03445 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
HEBBHNLP_03446 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEBBHNLP_03447 1.29e-193 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HEBBHNLP_03448 1.14e-255 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
HEBBHNLP_03449 1.01e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HEBBHNLP_03450 1.24e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HEBBHNLP_03451 2.34e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
HEBBHNLP_03453 7.9e-180 ysnF - - S - - - protein conserved in bacteria
HEBBHNLP_03454 1.2e-100 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
HEBBHNLP_03456 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HEBBHNLP_03457 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HEBBHNLP_03458 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HEBBHNLP_03459 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HEBBHNLP_03460 3.02e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HEBBHNLP_03461 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEBBHNLP_03462 4.4e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEBBHNLP_03463 1.11e-239 ysoA - - H - - - Tetratricopeptide repeat
HEBBHNLP_03464 8.87e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HEBBHNLP_03465 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HEBBHNLP_03466 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
HEBBHNLP_03467 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HEBBHNLP_03468 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HEBBHNLP_03469 9.62e-116 ysxD - - - - - - -
HEBBHNLP_03470 9.14e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HEBBHNLP_03471 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
HEBBHNLP_03472 8.91e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HEBBHNLP_03473 1.01e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
HEBBHNLP_03474 3.7e-233 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
HEBBHNLP_03475 1.18e-310 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
HEBBHNLP_03476 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
HEBBHNLP_03477 4.82e-252 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HEBBHNLP_03478 1.53e-35 - - - - - - - -
HEBBHNLP_03479 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HEBBHNLP_03480 6.38e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HEBBHNLP_03481 3.08e-162 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HEBBHNLP_03482 1.37e-207 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
HEBBHNLP_03483 3.08e-58 orfX1 - - L - - - Transposase
HEBBHNLP_03484 2.28e-172 - - - L - - - Integrase core domain
HEBBHNLP_03485 8.25e-131 maf - - D ko:K06287 - ko00000 septum formation protein Maf
HEBBHNLP_03486 1.39e-161 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
HEBBHNLP_03487 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
HEBBHNLP_03488 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HEBBHNLP_03489 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
HEBBHNLP_03490 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HEBBHNLP_03491 6.84e-185 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
HEBBHNLP_03492 1.75e-185 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
HEBBHNLP_03493 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
HEBBHNLP_03494 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HEBBHNLP_03495 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
HEBBHNLP_03496 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HEBBHNLP_03497 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
HEBBHNLP_03498 5.59e-308 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HEBBHNLP_03499 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
HEBBHNLP_03500 1.43e-208 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
HEBBHNLP_03501 1.44e-122 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
HEBBHNLP_03502 2.25e-275 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HEBBHNLP_03503 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
HEBBHNLP_03504 2.51e-202 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
HEBBHNLP_03505 7.94e-273 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HEBBHNLP_03506 1.99e-216 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
HEBBHNLP_03507 2.55e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEBBHNLP_03508 8.63e-165 yebC - - K - - - transcriptional regulatory protein
HEBBHNLP_03509 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
HEBBHNLP_03510 2.55e-67 - - - S - - - Family of unknown function (DUF5412)
HEBBHNLP_03512 1.57e-150 yrzF - - T - - - serine threonine protein kinase
HEBBHNLP_03513 2.77e-248 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
HEBBHNLP_03514 0.0 csbX - - EGP - - - the major facilitator superfamily
HEBBHNLP_03515 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
HEBBHNLP_03516 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HEBBHNLP_03517 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HEBBHNLP_03518 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
HEBBHNLP_03519 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HEBBHNLP_03520 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HEBBHNLP_03521 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
HEBBHNLP_03522 1.46e-96 yrzE - - S - - - Protein of unknown function (DUF3792)
HEBBHNLP_03523 5.83e-143 yrbG - - S - - - membrane
HEBBHNLP_03524 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEBBHNLP_03525 5.53e-65 yrzD - - S - - - Post-transcriptional regulator
HEBBHNLP_03526 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HEBBHNLP_03527 2.65e-113 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
HEBBHNLP_03528 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
HEBBHNLP_03529 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HEBBHNLP_03530 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HEBBHNLP_03531 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEBBHNLP_03532 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HEBBHNLP_03533 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
HEBBHNLP_03535 3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HEBBHNLP_03536 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HEBBHNLP_03537 6.57e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HEBBHNLP_03538 9.91e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HEBBHNLP_03539 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
HEBBHNLP_03540 1.8e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HEBBHNLP_03541 2.4e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HEBBHNLP_03542 1.02e-38 yrrB - - S - - - COG0457 FOG TPR repeat
HEBBHNLP_03543 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HEBBHNLP_03544 1.44e-107 yrrD - - S - - - protein conserved in bacteria
HEBBHNLP_03545 8.4e-42 yrzR - - - - - - -
HEBBHNLP_03546 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
HEBBHNLP_03547 1.08e-138 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEBBHNLP_03548 3.24e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEBBHNLP_03549 1.01e-184 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HEBBHNLP_03550 1.28e-167 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HEBBHNLP_03551 7.23e-241 yrrI - - S - - - AI-2E family transporter
HEBBHNLP_03552 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HEBBHNLP_03553 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
HEBBHNLP_03554 3.18e-92 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HEBBHNLP_03555 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
HEBBHNLP_03556 6.17e-241 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEBBHNLP_03557 6.92e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
HEBBHNLP_03558 2.57e-221 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
HEBBHNLP_03559 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
HEBBHNLP_03560 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HEBBHNLP_03561 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEBBHNLP_03562 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
HEBBHNLP_03563 1e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
HEBBHNLP_03564 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
HEBBHNLP_03565 3.44e-153 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
HEBBHNLP_03566 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HEBBHNLP_03567 3.35e-216 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
HEBBHNLP_03568 8.55e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HEBBHNLP_03569 6.93e-49 yrhC - - S - - - YrhC-like protein
HEBBHNLP_03570 1.73e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
HEBBHNLP_03571 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
HEBBHNLP_03572 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
HEBBHNLP_03573 3.96e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
HEBBHNLP_03575 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
HEBBHNLP_03576 8.67e-124 yrhH - - Q - - - methyltransferase
HEBBHNLP_03577 2.26e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
HEBBHNLP_03578 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
HEBBHNLP_03579 6.32e-59 yrhK - - S - - - YrhK-like protein
HEBBHNLP_03580 0.0 oatA - - I - - - Acyltransferase family
HEBBHNLP_03581 2.88e-190 rsiV - - S - - - Protein of unknown function (DUF3298)
HEBBHNLP_03582 5.77e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEBBHNLP_03583 1.14e-191 yrhO - - K - - - Archaeal transcriptional regulator TrmB
HEBBHNLP_03584 2.68e-135 yrhP - - E - - - LysE type translocator
HEBBHNLP_03585 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HEBBHNLP_03586 0.0 levR - - K - - - PTS system fructose IIA component
HEBBHNLP_03587 2.66e-97 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HEBBHNLP_03588 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
HEBBHNLP_03589 2.79e-166 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HEBBHNLP_03590 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HEBBHNLP_03591 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HEBBHNLP_03592 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
HEBBHNLP_03593 1.09e-249 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
HEBBHNLP_03594 3.05e-09 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
HEBBHNLP_03595 3.17e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
HEBBHNLP_03596 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
HEBBHNLP_03597 6.11e-36 yraE - - - ko:K06440 - ko00000 -
HEBBHNLP_03598 1.97e-278 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HEBBHNLP_03599 3.77e-81 yraF - - M - - - Spore coat protein
HEBBHNLP_03600 1.2e-49 yraG - - - ko:K06440 - ko00000 -
HEBBHNLP_03601 1.34e-86 - - - E - - - Glyoxalase-like domain
HEBBHNLP_03602 2.4e-80 - - - T - - - sh3 domain protein
HEBBHNLP_03603 4.65e-80 - - - T - - - sh3 domain protein
HEBBHNLP_03604 6.64e-188 - - - S - - - Alpha beta hydrolase
HEBBHNLP_03605 1.45e-55 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEBBHNLP_03606 3.71e-198 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HEBBHNLP_03607 1.15e-260 yraM - - S - - - PrpF protein
HEBBHNLP_03608 7e-209 yraN - - K - - - Transcriptional regulator
HEBBHNLP_03609 3.27e-85 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HEBBHNLP_03610 1.01e-154 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HEBBHNLP_03611 1.64e-237 yrpG - - C - - - Aldo/keto reductase family
HEBBHNLP_03612 6.39e-124 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEBBHNLP_03613 2e-162 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HEBBHNLP_03615 2.39e-162 yrpD - - S - - - Domain of unknown function, YrpD
HEBBHNLP_03616 4.23e-246 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HEBBHNLP_03617 2.45e-211 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
HEBBHNLP_03618 3.34e-117 yrdA - - S - - - DinB family
HEBBHNLP_03619 3.12e-73 - - - S - - - Protein of unknown function (DUF2568)
HEBBHNLP_03620 7.08e-129 yrdC - - Q - - - Isochorismatase family
HEBBHNLP_03622 3.32e-282 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HEBBHNLP_03623 7.91e-55 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
HEBBHNLP_03624 4.82e-103 bkdR - - K - - - helix_turn_helix ASNC type
HEBBHNLP_03625 1.33e-175 azlC - - E - - - AzlC protein
HEBBHNLP_03626 3.26e-65 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
HEBBHNLP_03627 4.99e-292 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HEBBHNLP_03628 2e-211 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
HEBBHNLP_03629 1.32e-248 trkA - - P ko:K07222 - ko00000 Oxidoreductase
HEBBHNLP_03630 2.83e-203 - - - K - - - Transcriptional regulator
HEBBHNLP_03631 8.86e-219 yrdR - - EG - - - EamA-like transporter family
HEBBHNLP_03632 2.45e-23 - - - S - - - YrzO-like protein
HEBBHNLP_03633 3.06e-299 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HEBBHNLP_03634 3.73e-109 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
HEBBHNLP_03635 4.39e-268 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
HEBBHNLP_03636 3.56e-194 bltR - - K - - - helix_turn_helix, mercury resistance
HEBBHNLP_03639 7.94e-23 yqaO - - S - - - Phage-like element PBSX protein XtrA
HEBBHNLP_03640 7.44e-05 - - - S - - - Bacillus cereus group antimicrobial protein
HEBBHNLP_03644 3.3e-41 yqaS - - L - - - DNA packaging
HEBBHNLP_03645 3.4e-10 xkdM - - S - - - Phage tail tube protein
HEBBHNLP_03647 1.89e-40 - - - - - - - -
HEBBHNLP_03648 2.22e-36 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
HEBBHNLP_03653 3.69e-60 - - - - - - - -
HEBBHNLP_03654 2.45e-19 - - - S - - - SMI1 / KNR4 family
HEBBHNLP_03655 4.66e-20 - - - S - - - SMI1-KNR4 cell-wall
HEBBHNLP_03658 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
HEBBHNLP_03660 4.32e-120 - - - S - - - Tetratricopeptide repeat
HEBBHNLP_03661 8.47e-143 - - - C - - - Nitroreductase family
HEBBHNLP_03662 1.28e-73 - - - K - - - transcriptional
HEBBHNLP_03663 3.22e-129 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HEBBHNLP_03664 1.04e-198 - - - EGP - - - Major Facilitator Superfamily
HEBBHNLP_03665 3.69e-140 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBBHNLP_03666 3.14e-12 ptsH_1 - - G ko:K11189 - ko00000,ko02000 Phosphocarrier protein HPr
HEBBHNLP_03667 4.25e-226 - - - S ko:K06889 - ko00000 X-Pro dipeptidyl-peptidase (S15 family)
HEBBHNLP_03668 1.54e-113 - - - K - - - Transcriptional regulator C-terminal region
HEBBHNLP_03669 1.6e-24 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
HEBBHNLP_03671 7.53e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEBBHNLP_03672 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
HEBBHNLP_03673 1.05e-167 - - - - - - - -
HEBBHNLP_03674 2.45e-213 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
HEBBHNLP_03675 6.59e-135 yqeD - - S - - - SNARE associated Golgi protein
HEBBHNLP_03676 1.68e-176 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
HEBBHNLP_03677 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
HEBBHNLP_03679 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
HEBBHNLP_03680 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HEBBHNLP_03681 5.47e-197 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEBBHNLP_03682 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
HEBBHNLP_03683 2.03e-140 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HEBBHNLP_03684 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
HEBBHNLP_03685 1.14e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HEBBHNLP_03686 5.44e-176 yqeM - - Q - - - Methyltransferase
HEBBHNLP_03687 1.1e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEBBHNLP_03688 4.31e-134 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
HEBBHNLP_03689 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HEBBHNLP_03690 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HEBBHNLP_03691 2.36e-22 - - - S - - - YqzM-like protein
HEBBHNLP_03692 2.35e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HEBBHNLP_03693 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HEBBHNLP_03694 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HEBBHNLP_03695 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
HEBBHNLP_03696 1.17e-68 yqxA - - S - - - Protein of unknown function (DUF3679)
HEBBHNLP_03697 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HEBBHNLP_03698 1.68e-275 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
HEBBHNLP_03699 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HEBBHNLP_03700 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HEBBHNLP_03701 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HEBBHNLP_03702 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HEBBHNLP_03703 9.34e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
HEBBHNLP_03704 1.14e-177 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HEBBHNLP_03705 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
HEBBHNLP_03706 4.02e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
HEBBHNLP_03707 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HEBBHNLP_03708 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
HEBBHNLP_03709 6.26e-289 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
HEBBHNLP_03710 4.35e-192 yqfA - - S - - - UPF0365 protein
HEBBHNLP_03711 7.03e-60 yqfB - - - - - - -
HEBBHNLP_03712 2.07e-60 yqfC - - S - - - sporulation protein YqfC
HEBBHNLP_03713 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
HEBBHNLP_03714 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
HEBBHNLP_03716 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
HEBBHNLP_03717 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HEBBHNLP_03718 4.75e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HEBBHNLP_03719 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HEBBHNLP_03720 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEBBHNLP_03721 5.29e-27 - - - S - - - YqzL-like protein
HEBBHNLP_03722 7.48e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HEBBHNLP_03723 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HEBBHNLP_03724 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HEBBHNLP_03725 3.29e-144 ccpN - - K - - - CBS domain
HEBBHNLP_03726 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HEBBHNLP_03727 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
HEBBHNLP_03728 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HEBBHNLP_03729 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HEBBHNLP_03730 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
HEBBHNLP_03731 3.28e-148 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HEBBHNLP_03732 1.47e-266 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HEBBHNLP_03733 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HEBBHNLP_03734 1.17e-52 yqfQ - - S - - - YqfQ-like protein
HEBBHNLP_03735 2.21e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HEBBHNLP_03736 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HEBBHNLP_03737 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
HEBBHNLP_03738 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HEBBHNLP_03739 4.98e-106 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
HEBBHNLP_03740 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
HEBBHNLP_03741 2.04e-81 yqfX - - S - - - membrane
HEBBHNLP_03742 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HEBBHNLP_03743 1.58e-60 yqfZ - - M ko:K06417 - ko00000 LysM domain
HEBBHNLP_03744 2.74e-168 yqgB - - S - - - Protein of unknown function (DUF1189)
HEBBHNLP_03745 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
HEBBHNLP_03746 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
HEBBHNLP_03747 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
HEBBHNLP_03748 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
HEBBHNLP_03749 1.02e-202 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HEBBHNLP_03750 4.11e-202 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HEBBHNLP_03751 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
HEBBHNLP_03752 1.62e-188 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEBBHNLP_03753 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEBBHNLP_03754 2.4e-97 yqzC - - S - - - YceG-like family
HEBBHNLP_03755 2.81e-67 yqzD - - - - - - -
HEBBHNLP_03757 3.22e-247 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
HEBBHNLP_03758 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HEBBHNLP_03759 5.4e-135 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HEBBHNLP_03760 4.1e-15 yqgO - - - - - - -
HEBBHNLP_03761 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
HEBBHNLP_03762 1.27e-43 yqgQ - - S - - - Protein conserved in bacteria
HEBBHNLP_03763 2.31e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HEBBHNLP_03764 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HEBBHNLP_03765 8.36e-281 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
HEBBHNLP_03766 7.7e-256 yqgU - - - - - - -
HEBBHNLP_03767 7.34e-66 yqgV - - S - - - Thiamine-binding protein
HEBBHNLP_03768 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
HEBBHNLP_03769 1.52e-155 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
HEBBHNLP_03770 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
HEBBHNLP_03771 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
HEBBHNLP_03773 8.33e-191 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEBBHNLP_03774 4.95e-306 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HEBBHNLP_03775 7.17e-232 yqxL - - P - - - Mg2 transporter protein
HEBBHNLP_03776 2.91e-05 - - - S - - - Domain in cystathionine beta-synthase and other proteins.
HEBBHNLP_03777 5.23e-256 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HEBBHNLP_03778 1.19e-216 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
HEBBHNLP_03779 4.39e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
HEBBHNLP_03780 7.66e-91 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
HEBBHNLP_03781 1.77e-78 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
HEBBHNLP_03782 2.38e-45 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
HEBBHNLP_03783 1.08e-56 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
HEBBHNLP_03784 2.84e-36 yqzE - - S - - - YqzE-like protein
HEBBHNLP_03785 1.5e-69 yqzG - - S - - - Protein of unknown function (DUF3889)
HEBBHNLP_03786 2.45e-150 yqxM - - - ko:K19433 - ko00000 -
HEBBHNLP_03787 5.52e-93 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
HEBBHNLP_03788 3.14e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
HEBBHNLP_03789 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
HEBBHNLP_03790 1.39e-33 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
HEBBHNLP_03791 4.17e-193 yqhG - - S - - - Bacterial protein YqhG of unknown function
HEBBHNLP_03792 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
HEBBHNLP_03793 3.31e-262 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
HEBBHNLP_03794 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HEBBHNLP_03795 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HEBBHNLP_03796 3.05e-82 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
HEBBHNLP_03797 1.07e-202 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HEBBHNLP_03798 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HEBBHNLP_03799 9.94e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HEBBHNLP_03800 5.18e-81 yqhP - - - - - - -
HEBBHNLP_03801 2.98e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
HEBBHNLP_03802 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
HEBBHNLP_03803 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
HEBBHNLP_03804 6.04e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
HEBBHNLP_03805 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HEBBHNLP_03806 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
HEBBHNLP_03807 8.22e-217 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
HEBBHNLP_03808 4.68e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
HEBBHNLP_03809 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
HEBBHNLP_03810 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
HEBBHNLP_03811 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
HEBBHNLP_03812 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
HEBBHNLP_03813 9.25e-150 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
HEBBHNLP_03814 4.04e-134 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
HEBBHNLP_03815 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HEBBHNLP_03816 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HEBBHNLP_03817 1.65e-88 yqhY - - S - - - protein conserved in bacteria
HEBBHNLP_03818 1.95e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HEBBHNLP_03819 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEBBHNLP_03820 4.13e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEBBHNLP_03821 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEBBHNLP_03822 3.45e-208 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HEBBHNLP_03823 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEBBHNLP_03824 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
HEBBHNLP_03825 8.85e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HEBBHNLP_03826 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HEBBHNLP_03827 2.96e-302 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
HEBBHNLP_03828 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HEBBHNLP_03830 6.63e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HEBBHNLP_03831 4.74e-37 - - - - - - - -
HEBBHNLP_03832 9.4e-138 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
HEBBHNLP_03833 3.39e-168 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HEBBHNLP_03834 1.91e-279 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HEBBHNLP_03835 3.28e-197 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
HEBBHNLP_03836 1.42e-267 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
HEBBHNLP_03837 1.85e-264 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HEBBHNLP_03838 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
HEBBHNLP_03839 1.52e-209 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HEBBHNLP_03840 5.23e-45 yqzF - - S - - - Protein of unknown function (DUF2627)
HEBBHNLP_03841 0.0 bkdR - - KT - - - Transcriptional regulator
HEBBHNLP_03842 7.41e-200 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
HEBBHNLP_03843 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HEBBHNLP_03844 5.62e-254 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
HEBBHNLP_03845 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEBBHNLP_03846 1.92e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEBBHNLP_03847 1.98e-234 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEBBHNLP_03848 1.53e-287 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEBBHNLP_03849 3.69e-194 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
HEBBHNLP_03850 2.96e-265 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
HEBBHNLP_03851 9.96e-213 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HEBBHNLP_03852 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
HEBBHNLP_03853 1.18e-174 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HEBBHNLP_03854 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HEBBHNLP_03855 5.2e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HEBBHNLP_03856 8.21e-220 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
HEBBHNLP_03857 5.88e-127 yqjB - - S - - - protein conserved in bacteria
HEBBHNLP_03859 5.45e-94 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
HEBBHNLP_03860 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HEBBHNLP_03861 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
HEBBHNLP_03862 1.57e-177 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
HEBBHNLP_03863 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEBBHNLP_03864 1.77e-32 yqzJ - - - - - - -
HEBBHNLP_03865 1.84e-299 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEBBHNLP_03866 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEBBHNLP_03867 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HEBBHNLP_03868 2.2e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HEBBHNLP_03869 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HEBBHNLP_03870 3.17e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HEBBHNLP_03871 3.48e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HEBBHNLP_03872 0.0 rocB - - E - - - arginine degradation protein
HEBBHNLP_03873 5.62e-189 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEBBHNLP_03874 2.58e-226 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HEBBHNLP_03875 3.41e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBBHNLP_03876 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
HEBBHNLP_03877 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HEBBHNLP_03878 1.91e-52 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEBBHNLP_03880 1.08e-289 yqjV - - G - - - Major Facilitator Superfamily
HEBBHNLP_03882 3.31e-303 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEBBHNLP_03883 3.23e-66 yqiX - - S - - - YolD-like protein
HEBBHNLP_03884 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
HEBBHNLP_03885 1.85e-77 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
HEBBHNLP_03886 4.59e-248 yqkA - - K - - - GrpB protein
HEBBHNLP_03887 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
HEBBHNLP_03888 9.23e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
HEBBHNLP_03889 9.3e-220 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HEBBHNLP_03890 6.61e-26 yqkE - - S - - - Protein of unknown function (DUF3886)
HEBBHNLP_03891 1.04e-214 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
HEBBHNLP_03892 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
HEBBHNLP_03893 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
HEBBHNLP_03894 3.42e-279 yqxK - - L - - - DNA helicase
HEBBHNLP_03895 3.18e-77 ansR - - K - - - Transcriptional regulator
HEBBHNLP_03896 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
HEBBHNLP_03897 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
HEBBHNLP_03898 1.14e-309 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
HEBBHNLP_03899 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
HEBBHNLP_03900 7.27e-42 yqkK - - - - - - -
HEBBHNLP_03901 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HEBBHNLP_03902 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HEBBHNLP_03903 5.51e-50 - - - S - - - Protein of unknown function (DUF4227)
HEBBHNLP_03904 1.31e-212 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
HEBBHNLP_03905 6.8e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
HEBBHNLP_03906 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HEBBHNLP_03907 3.37e-271 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HEBBHNLP_03908 3e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
HEBBHNLP_03909 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HEBBHNLP_03910 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEBBHNLP_03911 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
HEBBHNLP_03912 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
HEBBHNLP_03913 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
HEBBHNLP_03914 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
HEBBHNLP_03915 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
HEBBHNLP_03916 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
HEBBHNLP_03917 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
HEBBHNLP_03918 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HEBBHNLP_03919 8.93e-192 ypuA - - S - - - Secreted protein
HEBBHNLP_03920 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEBBHNLP_03922 7.41e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
HEBBHNLP_03923 1.38e-131 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HEBBHNLP_03924 4.92e-71 ypuD - - - - - - -
HEBBHNLP_03925 2.07e-260 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HEBBHNLP_03926 2.5e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
HEBBHNLP_03927 5.16e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HEBBHNLP_03928 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HEBBHNLP_03929 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEBBHNLP_03930 1.7e-118 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
HEBBHNLP_03931 1.33e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HEBBHNLP_03932 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HEBBHNLP_03933 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
HEBBHNLP_03934 1.13e-270 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HEBBHNLP_03935 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
HEBBHNLP_03936 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
HEBBHNLP_03937 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HEBBHNLP_03938 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HEBBHNLP_03939 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
HEBBHNLP_03940 7.74e-278 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HEBBHNLP_03941 4.84e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBBHNLP_03942 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEBBHNLP_03943 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEBBHNLP_03944 2.65e-234 rsiX - - - - - - -
HEBBHNLP_03945 1.13e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HEBBHNLP_03946 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEBBHNLP_03947 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HEBBHNLP_03948 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
HEBBHNLP_03949 3.67e-254 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
HEBBHNLP_03950 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
HEBBHNLP_03951 2.92e-127 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
HEBBHNLP_03952 8.61e-143 ypbE - - M - - - Lysin motif
HEBBHNLP_03953 6.77e-105 ypbF - - S - - - Protein of unknown function (DUF2663)
HEBBHNLP_03954 8.04e-184 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HEBBHNLP_03955 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HEBBHNLP_03956 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HEBBHNLP_03957 1.85e-224 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
HEBBHNLP_03958 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
HEBBHNLP_03959 1.99e-207 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
HEBBHNLP_03960 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
HEBBHNLP_03961 1.81e-141 ypfA - - M - - - Flagellar protein YcgR
HEBBHNLP_03962 1.39e-29 - - - S - - - Family of unknown function (DUF5359)
HEBBHNLP_03963 3.91e-144 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HEBBHNLP_03964 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HEBBHNLP_03965 1.33e-234 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HEBBHNLP_03966 1.13e-11 - - - S - - - YpzI-like protein
HEBBHNLP_03967 1.11e-133 yphA - - - - - - -
HEBBHNLP_03968 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
HEBBHNLP_03969 5.91e-38 ypzH - - - - - - -
HEBBHNLP_03970 2.92e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HEBBHNLP_03971 1.55e-231 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HEBBHNLP_03972 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
HEBBHNLP_03973 2.14e-176 yphF - - - - - - -
HEBBHNLP_03974 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HEBBHNLP_03975 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HEBBHNLP_03976 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
HEBBHNLP_03977 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HEBBHNLP_03978 8.37e-176 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HEBBHNLP_03979 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HEBBHNLP_03980 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HEBBHNLP_03981 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HEBBHNLP_03982 3.03e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
HEBBHNLP_03983 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HEBBHNLP_03984 3.31e-262 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HEBBHNLP_03985 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HEBBHNLP_03986 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HEBBHNLP_03987 5e-229 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HEBBHNLP_03988 6.92e-144 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
HEBBHNLP_03989 9.07e-150 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
HEBBHNLP_03990 1.04e-291 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HEBBHNLP_03991 1.56e-185 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HEBBHNLP_03992 1.24e-256 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HEBBHNLP_03993 1.16e-262 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
HEBBHNLP_03994 2.33e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HEBBHNLP_03995 1.76e-297 ypiA - - S - - - COG0457 FOG TPR repeat
HEBBHNLP_03996 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
HEBBHNLP_03997 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
HEBBHNLP_03998 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
HEBBHNLP_03999 1.25e-165 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
HEBBHNLP_04000 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
HEBBHNLP_04001 1.56e-123 ypjA - - S - - - membrane
HEBBHNLP_04002 2.79e-182 ypjB - - S - - - sporulation protein
HEBBHNLP_04003 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HEBBHNLP_04004 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
HEBBHNLP_04005 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HEBBHNLP_04006 2.52e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
HEBBHNLP_04007 6.34e-165 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
HEBBHNLP_04008 8.18e-266 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
HEBBHNLP_04009 4.32e-278 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HEBBHNLP_04010 4.87e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HEBBHNLP_04011 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HEBBHNLP_04012 1.5e-197 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HEBBHNLP_04013 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HEBBHNLP_04014 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HEBBHNLP_04015 6.21e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
HEBBHNLP_04016 2.66e-102 ypmB - - S - - - protein conserved in bacteria
HEBBHNLP_04017 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HEBBHNLP_04018 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
HEBBHNLP_04019 1.1e-163 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
HEBBHNLP_04020 2.93e-157 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HEBBHNLP_04021 5.81e-121 ypoC - - - - - - -
HEBBHNLP_04022 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HEBBHNLP_04023 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HEBBHNLP_04024 3.07e-239 yppC - - S - - - Protein of unknown function (DUF2515)
HEBBHNLP_04027 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
HEBBHNLP_04028 9.21e-11 - - - S - - - YppF-like protein
HEBBHNLP_04029 1.45e-66 yppG - - S - - - YppG-like protein
HEBBHNLP_04030 1.24e-94 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HEBBHNLP_04031 5.3e-110 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
HEBBHNLP_04032 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HEBBHNLP_04033 8.41e-300 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
HEBBHNLP_04034 9.78e-130 ypsA - - S - - - Belongs to the UPF0398 family
HEBBHNLP_04035 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HEBBHNLP_04036 1.92e-284 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HEBBHNLP_04038 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
HEBBHNLP_04039 5.63e-177 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBBHNLP_04040 2.96e-203 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HEBBHNLP_04041 7.8e-238 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
HEBBHNLP_04042 2.83e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
HEBBHNLP_04043 1.47e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
HEBBHNLP_04044 4.09e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HEBBHNLP_04045 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HEBBHNLP_04046 5.51e-127 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HEBBHNLP_04047 1.66e-289 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
HEBBHNLP_04048 2.63e-265 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
HEBBHNLP_04049 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
HEBBHNLP_04051 0.0 ypbR - - S - - - Dynamin family
HEBBHNLP_04052 6.77e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
HEBBHNLP_04053 1.08e-11 - - - - - - - -
HEBBHNLP_04054 2.26e-213 ypcP - - L - - - 5'3' exonuclease
HEBBHNLP_04055 5.23e-05 - - - - ko:K06429 - ko00000 -
HEBBHNLP_04056 7.64e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
HEBBHNLP_04057 2.12e-155 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HEBBHNLP_04058 1.1e-160 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
HEBBHNLP_04059 7.99e-41 ypeQ - - S - - - Zinc-finger
HEBBHNLP_04060 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
HEBBHNLP_04061 1.17e-22 degR - - - - - - -
HEBBHNLP_04062 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
HEBBHNLP_04063 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HEBBHNLP_04064 1.23e-224 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HEBBHNLP_04065 3.13e-114 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
HEBBHNLP_04066 4.18e-141 yagB - - S ko:K06950 - ko00000 phosphohydrolase
HEBBHNLP_04067 2.32e-203 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
HEBBHNLP_04068 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
HEBBHNLP_04069 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
HEBBHNLP_04070 8.04e-183 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
HEBBHNLP_04071 9.94e-148 ypjP - - S - - - YpjP-like protein
HEBBHNLP_04072 3.63e-120 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
HEBBHNLP_04073 3.9e-121 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HEBBHNLP_04074 9.49e-143 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HEBBHNLP_04075 2.3e-142 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
HEBBHNLP_04076 1.4e-236 yplP - - K - - - Transcriptional regulator
HEBBHNLP_04077 3.64e-310 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HEBBHNLP_04078 2.12e-53 ypmP - - S - - - Protein of unknown function (DUF2535)
HEBBHNLP_04079 2.77e-140 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HEBBHNLP_04080 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
HEBBHNLP_04081 1.95e-128 ypmS - - S - - - protein conserved in bacteria
HEBBHNLP_04082 8.69e-40 ypmT - - S - - - Uncharacterized ympT
HEBBHNLP_04083 9.99e-290 mepA - - V - - - MATE efflux family protein
HEBBHNLP_04084 4.14e-94 ypoP - - K - - - transcriptional
HEBBHNLP_04085 1.99e-132 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEBBHNLP_04086 4.13e-102 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HEBBHNLP_04087 1.02e-123 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
HEBBHNLP_04088 0.0 yokA - - L - - - Recombinase
HEBBHNLP_04090 2.74e-85 - - - S - - - SMI1 / KNR4 family
HEBBHNLP_04091 0.000596 - - - S - - - DNase/tRNase domain of colicin-like bacteriocin
HEBBHNLP_04092 7.22e-198 yokD 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 aminoglycoside
HEBBHNLP_04093 7.97e-108 - - - S - - - Bacterial PH domain
HEBBHNLP_04094 1.17e-167 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
HEBBHNLP_04095 1.39e-47 - - - - - - - -
HEBBHNLP_04096 1.24e-31 yokH - - G - - - SMI1 / KNR4 family
HEBBHNLP_04097 2.1e-28 yokH - - G - - - SMI1 / KNR4 family
HEBBHNLP_04098 3.42e-77 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HEBBHNLP_04099 1.29e-252 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HEBBHNLP_04101 1.76e-57 - - - L - - - Belongs to the 'phage' integrase family
HEBBHNLP_04102 4.81e-16 - - - - - - - -
HEBBHNLP_04103 1.32e-38 - - - - - - - -
HEBBHNLP_04105 1.13e-50 - - - - - - - -
HEBBHNLP_04108 1.01e-65 - - - - - - - -
HEBBHNLP_04111 9.15e-23 - - - - - - - -
HEBBHNLP_04116 8.19e-79 - - - - - - - -
HEBBHNLP_04119 1.12e-99 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HEBBHNLP_04121 6.55e-82 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
HEBBHNLP_04122 3.83e-278 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
HEBBHNLP_04123 1.62e-228 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
HEBBHNLP_04124 1.79e-82 cgeA - - - ko:K06319 - ko00000 -
HEBBHNLP_04125 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
HEBBHNLP_04126 6.61e-183 yiiD - - K ko:K06323 - ko00000 acetyltransferase
HEBBHNLP_04128 7.76e-314 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEBBHNLP_04129 2.21e-157 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HEBBHNLP_04130 2.22e-151 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HEBBHNLP_04131 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
HEBBHNLP_04132 8.74e-196 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
HEBBHNLP_04133 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
HEBBHNLP_04134 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
HEBBHNLP_04135 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
HEBBHNLP_04136 7.44e-159 yodN - - - - - - -
HEBBHNLP_04138 5.18e-34 yozD - - S - - - YozD-like protein
HEBBHNLP_04139 4.02e-138 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HEBBHNLP_04140 1.17e-71 yodL - - S - - - YodL-like
HEBBHNLP_04141 2.08e-12 - - - - - - - -
HEBBHNLP_04142 1.68e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
HEBBHNLP_04143 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
HEBBHNLP_04144 4.86e-41 yodI - - - - - - -
HEBBHNLP_04145 3.03e-166 yodH - - Q - - - Methyltransferase
HEBBHNLP_04146 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HEBBHNLP_04147 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEBBHNLP_04148 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
HEBBHNLP_04149 2.78e-222 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HEBBHNLP_04150 1.31e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
HEBBHNLP_04151 1.11e-139 yodC - - C - - - nitroreductase
HEBBHNLP_04152 2.63e-73 yodB - - K - - - transcriptional
HEBBHNLP_04153 3.97e-84 iolK - - S - - - tautomerase
HEBBHNLP_04154 1.13e-290 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HEBBHNLP_04155 1.95e-14 - - - - - - - -
HEBBHNLP_04156 2.88e-103 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
HEBBHNLP_04157 6.68e-207 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
HEBBHNLP_04158 7.55e-58 - - - - - - - -
HEBBHNLP_04159 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
HEBBHNLP_04160 3.71e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
HEBBHNLP_04161 2.05e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEBBHNLP_04162 2.06e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
HEBBHNLP_04164 3.54e-140 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEBBHNLP_04165 1.13e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
HEBBHNLP_04166 1.3e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HEBBHNLP_04167 3.62e-142 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HEBBHNLP_04168 5.19e-205 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
HEBBHNLP_04169 0.0 yojO - - P - - - Von Willebrand factor
HEBBHNLP_04170 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HEBBHNLP_04171 2.59e-264 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HEBBHNLP_04172 1.11e-212 yocS - - S ko:K03453 - ko00000 -transporter
HEBBHNLP_04173 1.25e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HEBBHNLP_04174 4.57e-210 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
HEBBHNLP_04175 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
HEBBHNLP_04176 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HEBBHNLP_04177 1.91e-42 yozC - - - - - - -
HEBBHNLP_04178 2.17e-74 yozO - - S - - - Bacterial PH domain
HEBBHNLP_04179 1.83e-49 yocN - - - - - - -
HEBBHNLP_04180 2.94e-55 yozN - - - - - - -
HEBBHNLP_04181 5.43e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HEBBHNLP_04182 3.93e-41 - - - - - - - -
HEBBHNLP_04183 2.87e-107 yocK - - T - - - general stress protein
HEBBHNLP_04184 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEBBHNLP_04185 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
HEBBHNLP_04186 1.67e-174 yocH - - M - - - COG1388 FOG LysM repeat
HEBBHNLP_04187 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEBBHNLP_04188 3.51e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEBBHNLP_04189 3.99e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
HEBBHNLP_04190 2.73e-240 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
HEBBHNLP_04191 6.27e-121 yocC - - - - - - -
HEBBHNLP_04192 4.31e-184 - - - - - - - -
HEBBHNLP_04193 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
HEBBHNLP_04194 3.28e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HEBBHNLP_04195 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
HEBBHNLP_04196 1.37e-116 yobW - - - - - - -
HEBBHNLP_04197 4.44e-224 yobV - - K - - - WYL domain
HEBBHNLP_04198 8.64e-112 - - - K - - - Bacterial transcription activator, effector binding domain
HEBBHNLP_04199 2.14e-166 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HEBBHNLP_04200 3.09e-127 yobS - - K - - - Transcriptional regulator
HEBBHNLP_04201 1.45e-180 - - - J - - - FR47-like protein
HEBBHNLP_04202 1.82e-171 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
HEBBHNLP_04203 9e-72 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
HEBBHNLP_04204 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
HEBBHNLP_04205 9e-116 yokH - - G - - - SMI1 / KNR4 family
HEBBHNLP_04206 3.28e-21 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HEBBHNLP_04207 1.95e-26 - - - - - - - -
HEBBHNLP_04209 6.4e-134 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HEBBHNLP_04211 9.95e-23 - - - - - - - -
HEBBHNLP_04212 1.32e-85 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
HEBBHNLP_04213 1.8e-97 - - - - - - - -
HEBBHNLP_04215 2.46e-10 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HEBBHNLP_04216 2.88e-105 yoaW - - - - - - -
HEBBHNLP_04217 4.01e-36 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HEBBHNLP_04218 6.23e-131 - - - S - - - Domain of unknown function (DUF3885)
HEBBHNLP_04219 1.32e-66 ynaF - - - - - - -
HEBBHNLP_04221 2.45e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HEBBHNLP_04226 1.83e-64 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
HEBBHNLP_04227 1.95e-172 - - - - - - - -
HEBBHNLP_04228 2.13e-44 yoaF - - - - - - -
HEBBHNLP_04230 2.11e-49 - - - S - - - TM2 domain
HEBBHNLP_04231 7.53e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
HEBBHNLP_04232 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
HEBBHNLP_04235 2.54e-215 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
HEBBHNLP_04236 3.43e-147 lin0465 - - S - - - DJ-1/PfpI family
HEBBHNLP_04237 3.26e-101 yoaW - - - - - - -
HEBBHNLP_04238 2.6e-201 yoaV - - EG - - - EamA-like transporter family
HEBBHNLP_04239 2.23e-201 yoaU - - K - - - LysR substrate binding domain
HEBBHNLP_04240 9.84e-192 yoaT - - S - - - Protein of unknown function (DUF817)
HEBBHNLP_04241 4.17e-40 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HEBBHNLP_04242 9.24e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
HEBBHNLP_04243 2.2e-216 yoaR - - V - - - vancomycin resistance protein
HEBBHNLP_04244 5.14e-111 - - - - - - - -
HEBBHNLP_04245 8.3e-24 yoaP - - K - - - YoaP-like
HEBBHNLP_04247 3.62e-292 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
HEBBHNLP_04250 5.08e-171 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
HEBBHNLP_04251 9.68e-251 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
HEBBHNLP_04252 1.79e-145 yoaK - - S - - - Membrane
HEBBHNLP_04253 4.33e-170 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
HEBBHNLP_04254 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
HEBBHNLP_04255 5.52e-283 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
HEBBHNLP_04256 4.77e-61 - - - S - - - Protein of unknown function (DUF4025)
HEBBHNLP_04257 1.46e-19 - - - - - - - -
HEBBHNLP_04259 6.2e-46 yoaF - - - - - - -
HEBBHNLP_04260 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEBBHNLP_04261 7.91e-233 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEBBHNLP_04262 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
HEBBHNLP_04263 2.24e-300 yoaB - - EGP - - - the major facilitator superfamily
HEBBHNLP_04264 4.48e-120 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HEBBHNLP_04265 1.48e-173 yoxB - - - - - - -
HEBBHNLP_04266 3.84e-51 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
HEBBHNLP_04267 2.28e-159 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBBHNLP_04268 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HEBBHNLP_04269 2.72e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEBBHNLP_04270 6.68e-262 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEBBHNLP_04271 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
HEBBHNLP_04272 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
HEBBHNLP_04273 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HEBBHNLP_04274 4.48e-232 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HEBBHNLP_04275 4.86e-198 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
HEBBHNLP_04276 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
HEBBHNLP_04277 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
HEBBHNLP_04278 1.14e-124 - - - L - - - Integrase
HEBBHNLP_04280 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
HEBBHNLP_04281 9.8e-313 yoeA - - V - - - MATE efflux family protein

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)