Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
CIKLKLIO_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CIKLKLIO_00002	4.62e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
CIKLKLIO_00003	2.15e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CIKLKLIO_00004	2.16e-238	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
CIKLKLIO_00005	8.02e-119	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
CIKLKLIO_00006	2.51e-159	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
CIKLKLIO_00007	5.17e-223	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
CIKLKLIO_00008	9.54e-285	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
CIKLKLIO_00009	5.17e-227	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CIKLKLIO_00010	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
CIKLKLIO_00011	0.0	-	-	-	-	-	-	-	-
CIKLKLIO_00012	7.29e-219	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
CIKLKLIO_00013	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
CIKLKLIO_00014	3.57e-144	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
CIKLKLIO_00015	1.33e-226	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CIKLKLIO_00016	1.86e-214	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CIKLKLIO_00017	4.63e-284	rpfB	-	-	S	ko:K21688	-	ko00000	G5
CIKLKLIO_00019	8.17e-15	-	-	-	O	-	-	-	Thioredoxin
CIKLKLIO_00020	2.17e-141	-	-	-	O	-	-	-	Thioredoxin
CIKLKLIO_00021	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
CIKLKLIO_00022	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
CIKLKLIO_00023	4.03e-43	-	-	-	T	-	-	-	LytTr DNA-binding domain
CIKLKLIO_00024	3.63e-35	-	-	-	T	-	-	-	LytTr DNA-binding domain
CIKLKLIO_00025	6.15e-153	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CIKLKLIO_00026	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
CIKLKLIO_00027	3.06e-158	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
CIKLKLIO_00028	4.65e-57	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
CIKLKLIO_00029	2.98e-115	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
CIKLKLIO_00030	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CIKLKLIO_00032	1.26e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CIKLKLIO_00033	1.91e-280	-	-	-	M	-	-	-	Glycosyltransferase like family 2
CIKLKLIO_00034	1.66e-95	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CIKLKLIO_00035	3.61e-61	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CIKLKLIO_00036	3.12e-307	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
CIKLKLIO_00037	2.91e-175	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA domain
CIKLKLIO_00038	7.62e-270	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CIKLKLIO_00039	4.11e-68	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
CIKLKLIO_00040	6.71e-130	-	-	-	L	-	-	-	Winged helix-turn helix
CIKLKLIO_00041	4.33e-189	istB	-	-	L	-	-	-	IstB-like ATP binding protein
CIKLKLIO_00042	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
CIKLKLIO_00043	3.27e-39	-	-	-	L	-	-	-	Winged helix-turn helix
CIKLKLIO_00044	3.33e-232	-	-	-	-	-	-	-	-
CIKLKLIO_00045	6.14e-191	-	-	-	U	ko:K10439,ko:K10440	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
CIKLKLIO_00046	3.35e-213	rbsA	3.6.3.17	-	G	ko:K10441,ko:K10542,ko:K17215	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_00047	6.91e-187	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
CIKLKLIO_00048	7.94e-167	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
CIKLKLIO_00049	7.31e-22	tnp3521a2	-	-	L	-	-	-	Integrase core domain
CIKLKLIO_00050	7.78e-200	-	-	-	-	-	-	-	-
CIKLKLIO_00051	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
CIKLKLIO_00052	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
CIKLKLIO_00053	6.27e-215	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
CIKLKLIO_00054	2.26e-222	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CIKLKLIO_00055	3.95e-273	-	-	-	EGP	-	-	-	Transmembrane secretion effector
CIKLKLIO_00056	9.75e-16	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
CIKLKLIO_00057	2.05e-314	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
CIKLKLIO_00058	1.58e-112	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
CIKLKLIO_00059	1.55e-20	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
CIKLKLIO_00060	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
CIKLKLIO_00061	8.51e-124	-	-	-	-	-	-	-	-
CIKLKLIO_00062	6.04e-144	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
CIKLKLIO_00063	1.28e-195	-	-	-	-	-	-	-	-
CIKLKLIO_00064	1.46e-187	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
CIKLKLIO_00065	5.53e-163	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
CIKLKLIO_00066	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
CIKLKLIO_00067	1.08e-105	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CIKLKLIO_00068	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
CIKLKLIO_00069	9.36e-296	-	-	-	GK	-	-	-	ROK family
CIKLKLIO_00070	9.35e-312	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CIKLKLIO_00071	4.48e-207	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_00072	7.15e-197	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_00073	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
CIKLKLIO_00074	3.3e-295	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
CIKLKLIO_00075	1.02e-182	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
CIKLKLIO_00079	6.32e-55	-	-	-	-	-	-	-	-
CIKLKLIO_00080	1.6e-248	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
CIKLKLIO_00081	8.82e-139	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
CIKLKLIO_00082	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
CIKLKLIO_00083	2.58e-178	nfrA	-	-	C	-	-	-	Nitroreductase family
CIKLKLIO_00084	3.72e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
CIKLKLIO_00085	1.06e-131	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
CIKLKLIO_00086	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CIKLKLIO_00087	3.83e-233	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
CIKLKLIO_00088	5.25e-197	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_00089	4.49e-196	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CIKLKLIO_00090	1.15e-136	-	-	-	S	-	-	-	Protein of unknown function, DUF624
CIKLKLIO_00091	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
CIKLKLIO_00092	2.49e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
CIKLKLIO_00093	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
CIKLKLIO_00094	0.0	-	-	-	E	ko:K03293	-	ko00000	Amino acid permease
CIKLKLIO_00095	1.11e-118	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
CIKLKLIO_00096	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
CIKLKLIO_00097	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
CIKLKLIO_00098	6.39e-233	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CIKLKLIO_00099	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
CIKLKLIO_00101	2.61e-236	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CIKLKLIO_00102	1.78e-154	-	-	-	-	-	-	-	-
CIKLKLIO_00103	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CIKLKLIO_00104	7.04e-63	-	-	-	-	-	-	-	-
CIKLKLIO_00105	2.58e-105	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
CIKLKLIO_00106	3.65e-189	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
CIKLKLIO_00107	8.8e-55	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
CIKLKLIO_00108	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
CIKLKLIO_00109	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
CIKLKLIO_00110	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
CIKLKLIO_00111	1.35e-237	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
CIKLKLIO_00112	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
CIKLKLIO_00113	4.08e-204	-	-	-	S	-	-	-	Glutamine amidotransferase domain
CIKLKLIO_00114	2.13e-181	-	-	-	T	ko:K06950	-	ko00000	HD domain
CIKLKLIO_00115	9.32e-244	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
CIKLKLIO_00116	0.0	-	-	-	V	-	-	-	ABC transporter permease
CIKLKLIO_00117	5.15e-306	yvhJ	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
CIKLKLIO_00118	2.74e-18	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
CIKLKLIO_00119	2.18e-199	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
CIKLKLIO_00120	7.76e-99	-	-	-	M	-	-	-	L,D-transpeptidase catalytic domain
CIKLKLIO_00121	3.74e-39	-	-	-	M	-	-	-	nuclease
CIKLKLIO_00122	4.76e-176	-	-	-	M	-	-	-	Glycosyl transferase family 2
CIKLKLIO_00123	0.0	-	-	-	-	-	-	-	-
CIKLKLIO_00124	1.69e-262	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CIKLKLIO_00125	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CIKLKLIO_00126	5.34e-215	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CIKLKLIO_00127	1.16e-152	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
CIKLKLIO_00128	2.23e-206	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIKLKLIO_00129	0.0	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
CIKLKLIO_00130	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
CIKLKLIO_00131	2.5e-227	-	-	-	S	-	-	-	Predicted membrane protein (DUF2142)
CIKLKLIO_00132	9.73e-255	-	-	-	M	-	-	-	Glycosyltransferase like family 2
CIKLKLIO_00133	6.05e-47	-	-	-	-	-	-	-	-
CIKLKLIO_00134	1.14e-89	xylR	-	-	GK	-	-	-	ROK family
CIKLKLIO_00135	6.75e-212	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
CIKLKLIO_00136	1.04e-97	-	-	-	G	-	-	-	ABC-type sugar transport system periplasmic component
CIKLKLIO_00137	3.85e-144	-	-	-	G	-	-	-	ATPases associated with a variety of cellular activities
CIKLKLIO_00138	9.99e-96	-	-	-	P	-	-	-	branched-chain amino acid ABC transporter, permease protein
CIKLKLIO_00139	1.41e-72	-	-	-	G	-	-	-	Branched-chain amino acid transport system / permease component
CIKLKLIO_00140	5.85e-50	hxlB	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
CIKLKLIO_00141	1.34e-296	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
CIKLKLIO_00142	2.07e-217	-	-	-	-	-	-	-	-
CIKLKLIO_00143	9.71e-167	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
CIKLKLIO_00144	7.26e-203	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
CIKLKLIO_00145	1.2e-210	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
CIKLKLIO_00146	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CIKLKLIO_00148	5.84e-278	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
CIKLKLIO_00149	2.2e-275	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
CIKLKLIO_00150	1.05e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CIKLKLIO_00151	9.47e-151	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CIKLKLIO_00152	8.49e-66	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_00153	0.0	-	-	-	G	-	-	-	N-terminal domain of (some) glycogen debranching enzymes
CIKLKLIO_00154	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
CIKLKLIO_00155	4.33e-189	istB	-	-	L	-	-	-	IstB-like ATP binding protein
CIKLKLIO_00156	1.47e-177	-	-	-	-	-	-	-	-
CIKLKLIO_00157	5.3e-316	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
CIKLKLIO_00158	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CIKLKLIO_00159	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
CIKLKLIO_00160	5.82e-182	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
CIKLKLIO_00161	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CIKLKLIO_00162	1.9e-170	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CIKLKLIO_00163	4.58e-26	-	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
CIKLKLIO_00164	3.25e-25	-	-	-	T	-	-	-	Histidine kinase
CIKLKLIO_00165	2.41e-279	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
CIKLKLIO_00166	9.29e-169	-	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_00167	1.05e-135	-	-	-	S	-	-	-	L-2-amino-thiazoline-4-carboxylic acid hydrolase
CIKLKLIO_00168	1.61e-180	-	-	-	P	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_00169	4.27e-155	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_00170	2.62e-201	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
CIKLKLIO_00171	0.0	nox	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
CIKLKLIO_00172	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CIKLKLIO_00173	3.54e-278	-	-	-	G	-	-	-	Transmembrane secretion effector
CIKLKLIO_00174	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
CIKLKLIO_00175	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CIKLKLIO_00176	8.89e-72	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
CIKLKLIO_00177	1.02e-65	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
CIKLKLIO_00178	1.31e-302	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
CIKLKLIO_00179	9.25e-231	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CIKLKLIO_00180	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
CIKLKLIO_00181	6.72e-118	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
CIKLKLIO_00182	3.47e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF1778)
CIKLKLIO_00183	8.7e-178	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_00184	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
CIKLKLIO_00185	1.36e-244	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
CIKLKLIO_00186	0.0	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
CIKLKLIO_00187	5.27e-191	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
CIKLKLIO_00188	9.55e-271	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
CIKLKLIO_00189	1.15e-190	-	-	-	S	ko:K07046	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Amidohydrolase
CIKLKLIO_00190	1.21e-213	-	4.1.2.28	-	EM	ko:K22397	ko00040,map00040	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
CIKLKLIO_00191	1.58e-213	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
CIKLKLIO_00192	5.15e-295	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
CIKLKLIO_00193	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
CIKLKLIO_00194	1.01e-62	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
CIKLKLIO_00195	1.44e-51	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
CIKLKLIO_00196	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CIKLKLIO_00197	1.3e-250	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CIKLKLIO_00198	4.54e-303	-	-	-	G	-	-	-	polysaccharide deacetylase
CIKLKLIO_00199	6.81e-293	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
CIKLKLIO_00201	4.95e-44	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CIKLKLIO_00202	1.43e-169	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
CIKLKLIO_00203	5e-96	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CIKLKLIO_00204	1.75e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CIKLKLIO_00205	4.55e-212	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
CIKLKLIO_00206	0.0	-	-	-	-	-	-	-	-
CIKLKLIO_00207	2.99e-191	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
CIKLKLIO_00208	3.36e-119	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
CIKLKLIO_00209	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
CIKLKLIO_00210	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
CIKLKLIO_00211	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
CIKLKLIO_00213	8.22e-58	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
CIKLKLIO_00217	2.5e-81	-	-	-	S	-	-	-	Alpha/beta hydrolase family
CIKLKLIO_00218	1.4e-12	-	-	-	-	-	-	-	-
CIKLKLIO_00219	2.66e-249	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CIKLKLIO_00220	4.79e-34	yxiO	-	-	G	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Major facilitator Superfamily
CIKLKLIO_00221	3.44e-70	-	-	-	L	-	-	-	RelB antitoxin
CIKLKLIO_00222	2.84e-79	-	-	-	T	-	-	-	Toxic component of a toxin-antitoxin (TA) module
CIKLKLIO_00223	9.99e-107	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CIKLKLIO_00224	7.92e-306	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
CIKLKLIO_00225	9.29e-250	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
CIKLKLIO_00226	1.05e-40	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
CIKLKLIO_00227	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
CIKLKLIO_00228	4.75e-132	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
CIKLKLIO_00229	1.01e-226	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
CIKLKLIO_00230	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
CIKLKLIO_00231	2.22e-256	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
CIKLKLIO_00232	1.33e-193	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
CIKLKLIO_00233	2.92e-160	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CIKLKLIO_00234	3.83e-122	-	-	-	D	-	-	-	nuclear chromosome segregation
CIKLKLIO_00235	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
CIKLKLIO_00236	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
CIKLKLIO_00237	2.09e-129	-	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
CIKLKLIO_00238	1.3e-240	-	-	-	K	-	-	-	Periplasmic binding protein domain
CIKLKLIO_00239	7.12e-304	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
CIKLKLIO_00240	7.01e-217	-	-	-	U	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_00241	7.49e-196	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_00242	0.0	kojP	2.4.1.230, 2.4.1.64	GH65	G	ko:K05342,ko:K10231	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
CIKLKLIO_00243	8.71e-107	kojP	2.4.1.230, 2.4.1.64	GH65	G	ko:K05342,ko:K10231	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
CIKLKLIO_00244	2.29e-200	-	-	-	EG	-	-	-	EamA-like transporter family
CIKLKLIO_00245	5.26e-148	pgmB	5.4.2.6	-	S	ko:K01838,ko:K04844	ko00500,map00500	ko00000,ko00001,ko01000	phosphonoacetaldehyde hydrolase activity
CIKLKLIO_00246	1.57e-171	-	3.2.1.23	-	G	ko:K12111	ko00052,ko00511,ko01100,map00052,map00511,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
CIKLKLIO_00247	0.0	-	3.2.1.23	-	G	ko:K12111	ko00052,ko00511,ko01100,map00052,map00511,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
CIKLKLIO_00248	1.97e-111	-	-	-	G	ko:K12112	ko00052,ko00511,ko01100,map00052,map00511,map01100	ko00000,ko00001	YhcH YjgK YiaL family protein
CIKLKLIO_00249	3.98e-278	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CIKLKLIO_00250	1.57e-298	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CIKLKLIO_00251	6.04e-159	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CIKLKLIO_00252	6.8e-308	-	-	-	EGP	-	-	-	Sugar (and other) transporter
CIKLKLIO_00253	3.14e-279	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
CIKLKLIO_00254	1.5e-182	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
CIKLKLIO_00255	2.32e-260	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
CIKLKLIO_00256	6.67e-212	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
CIKLKLIO_00257	1.86e-221	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
CIKLKLIO_00258	4.51e-190	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CIKLKLIO_00259	0.0	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
CIKLKLIO_00260	1.97e-186	-	-	-	S	-	-	-	alpha beta
CIKLKLIO_00261	2.41e-113	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CIKLKLIO_00262	1.06e-73	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CIKLKLIO_00263	1.79e-282	-	-	-	T	-	-	-	Forkhead associated domain
CIKLKLIO_00264	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
CIKLKLIO_00265	6.79e-24	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
CIKLKLIO_00266	9.74e-138	-	-	-	NO	-	-	-	SAF
CIKLKLIO_00267	6.24e-43	-	-	-	S	-	-	-	Putative regulatory protein
CIKLKLIO_00268	1.75e-77	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
CIKLKLIO_00269	2.1e-112	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
CIKLKLIO_00270	1.38e-185	-	-	-	-	-	-	-	-
CIKLKLIO_00271	1.73e-63	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CIKLKLIO_00275	1.03e-34	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
CIKLKLIO_00276	2.07e-281	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
CIKLKLIO_00277	0.0	-	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
CIKLKLIO_00278	4.51e-79	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
CIKLKLIO_00279	1.25e-285	dapC	-	-	E	-	-	-	Aminotransferase class I and II
CIKLKLIO_00280	6.01e-304	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CIKLKLIO_00281	3.33e-23	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
CIKLKLIO_00282	5.45e-96	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
CIKLKLIO_00284	2.08e-30	-	-	-	-	-	-	-	-
CIKLKLIO_00285	7.41e-277	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
CIKLKLIO_00286	2.69e-312	-	-	-	G	ko:K02027,ko:K10227	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CIKLKLIO_00287	2.42e-208	-	-	-	U	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_00288	7.21e-205	-	-	-	U	ko:K02026,ko:K10190	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_00289	1.16e-311	-	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
CIKLKLIO_00290	1.04e-147	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
CIKLKLIO_00291	1.22e-235	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIKLKLIO_00292	6.88e-144	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
CIKLKLIO_00293	9.47e-152	-	-	-	-	-	-	-	-
CIKLKLIO_00294	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
CIKLKLIO_00295	5.33e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CIKLKLIO_00296	9.6e-106	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
CIKLKLIO_00297	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
CIKLKLIO_00298	2.47e-227	-	1.1.1.1, 1.1.1.287, 1.6.5.5	-	C	ko:K00001,ko:K00344,ko:K17818	ko00010,ko00040,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
CIKLKLIO_00299	3.04e-296	csbX	-	-	EGP	-	-	-	Major Facilitator Superfamily
CIKLKLIO_00300	2.66e-97	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CIKLKLIO_00301	9.79e-275	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
CIKLKLIO_00302	1.73e-248	csbX	-	-	EGP	-	-	-	Major Facilitator Superfamily
CIKLKLIO_00303	6.77e-247	-	1.1.1.9	-	C	ko:K05351	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
CIKLKLIO_00304	2.64e-217	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
CIKLKLIO_00305	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
CIKLKLIO_00306	7.26e-185	-	-	-	S	-	-	-	YwiC-like protein
CIKLKLIO_00307	1.15e-173	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
CIKLKLIO_00308	9.35e-68	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
CIKLKLIO_00309	1.11e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CIKLKLIO_00310	9.78e-151	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
CIKLKLIO_00311	2.54e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CIKLKLIO_00312	3.85e-195	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CIKLKLIO_00313	1.4e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CIKLKLIO_00314	1.09e-74	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CIKLKLIO_00315	1.85e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CIKLKLIO_00316	3.85e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CIKLKLIO_00317	1.97e-49	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
CIKLKLIO_00318	1.11e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CIKLKLIO_00319	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CIKLKLIO_00320	5.4e-69	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CIKLKLIO_00321	1.95e-134	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CIKLKLIO_00322	7.06e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CIKLKLIO_00323	3.17e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CIKLKLIO_00324	1.33e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CIKLKLIO_00325	3.09e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CIKLKLIO_00326	2.25e-129	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CIKLKLIO_00327	3.26e-36	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
CIKLKLIO_00328	1.07e-98	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
CIKLKLIO_00329	9.34e-317	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CIKLKLIO_00330	2.57e-128	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CIKLKLIO_00331	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CIKLKLIO_00332	1.47e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
CIKLKLIO_00333	2e-82	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CIKLKLIO_00334	7.34e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CIKLKLIO_00335	2.61e-143	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIKLKLIO_00336	1.95e-75	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIKLKLIO_00337	2.36e-90	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
CIKLKLIO_00338	1.27e-218	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CIKLKLIO_00339	0.0	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
CIKLKLIO_00340	1.46e-194	-	-	-	E	-	-	-	Transglutaminase/protease-like homologues
CIKLKLIO_00342	1.71e-124	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
CIKLKLIO_00343	5.58e-162	-	-	-	-	-	-	-	-
CIKLKLIO_00344	4.55e-243	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
CIKLKLIO_00345	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CIKLKLIO_00346	3.5e-107	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CIKLKLIO_00347	3.85e-280	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CIKLKLIO_00348	2.05e-278	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
CIKLKLIO_00349	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CIKLKLIO_00350	3.39e-132	-	-	-	-	-	-	-	-
CIKLKLIO_00351	5.05e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
CIKLKLIO_00352	4.47e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CIKLKLIO_00353	6.4e-241	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CIKLKLIO_00354	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CIKLKLIO_00355	1.23e-96	-	-	-	K	-	-	-	Transcriptional regulator
CIKLKLIO_00356	2.68e-253	-	-	-	S	-	-	-	Protein conserved in bacteria
CIKLKLIO_00357	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
CIKLKLIO_00358	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
CIKLKLIO_00359	4.54e-209	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
CIKLKLIO_00360	3.39e-257	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
CIKLKLIO_00361	5.97e-307	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CIKLKLIO_00363	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
CIKLKLIO_00364	3.93e-223	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_00365	5.76e-217	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
CIKLKLIO_00366	0.0	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
CIKLKLIO_00367	3.43e-261	-	2.7.1.162	-	S	ko:K13059	-	ko00000,ko01000	Phosphotransferase enzyme family
CIKLKLIO_00368	4.59e-226	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
CIKLKLIO_00369	2.47e-153	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
CIKLKLIO_00370	2.84e-301	tcsS3	-	-	KT	-	-	-	PspC domain
CIKLKLIO_00371	0.0	pspC	-	-	KT	-	-	-	PspC domain
CIKLKLIO_00372	1.7e-94	-	-	-	-	-	-	-	-
CIKLKLIO_00373	0.0	-	-	-	S	ko:K06889	-	ko00000	alpha beta
CIKLKLIO_00374	4.35e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
CIKLKLIO_00375	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
CIKLKLIO_00376	1.02e-280	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
CIKLKLIO_00378	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
CIKLKLIO_00379	1.6e-221	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
CIKLKLIO_00380	3.9e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CIKLKLIO_00381	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
CIKLKLIO_00382	1.59e-239	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
CIKLKLIO_00383	2.69e-43	-	-	-	-	-	-	-	-
CIKLKLIO_00384	9.63e-270	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CIKLKLIO_00385	2.08e-216	-	-	-	S	-	-	-	CHAP domain
CIKLKLIO_00386	1.45e-138	-	-	-	M	-	-	-	NlpC/P60 family
CIKLKLIO_00387	9.3e-144	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
CIKLKLIO_00388	1.36e-241	-	-	-	T	-	-	-	Universal stress protein family
CIKLKLIO_00389	1.85e-95	-	-	-	O	-	-	-	OsmC-like protein
CIKLKLIO_00390	1.73e-214	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CIKLKLIO_00391	1.07e-164	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
CIKLKLIO_00392	3.01e-127	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
CIKLKLIO_00393	8.98e-16	-	-	-	E	-	-	-	AzlC protein
CIKLKLIO_00394	9.79e-143	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIKLKLIO_00395	2.52e-266	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
CIKLKLIO_00396	7.23e-288	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
CIKLKLIO_00397	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
CIKLKLIO_00399	1.98e-280	-	-	-	GK	-	-	-	ROK family
CIKLKLIO_00400	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
CIKLKLIO_00401	1.65e-27	-	-	-	L	-	-	-	Helix-turn-helix domain
CIKLKLIO_00402	2.41e-235	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
CIKLKLIO_00403	0.0	lacZ6	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
CIKLKLIO_00404	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
CIKLKLIO_00405	4.42e-19	-	-	-	L	-	-	-	Phage integrase family
CIKLKLIO_00407	9.16e-211	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CIKLKLIO_00410	0.0	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	Mycolic acid cyclopropane synthetase
CIKLKLIO_00411	1.73e-270	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
CIKLKLIO_00412	3.66e-225	-	-	-	M	-	-	-	Glycosyltransferase like family 2
CIKLKLIO_00413	0.0	-	-	-	S	-	-	-	AI-2E family transporter
CIKLKLIO_00414	7.16e-298	-	-	-	M	-	-	-	Glycosyl transferase family 21
CIKLKLIO_00415	2.74e-244	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_00416	0.0	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
CIKLKLIO_00417	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
CIKLKLIO_00418	4.76e-268	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CIKLKLIO_00419	2.66e-126	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
CIKLKLIO_00420	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CIKLKLIO_00421	1.9e-153	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
CIKLKLIO_00422	2.85e-207	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CIKLKLIO_00423	1.37e-288	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CIKLKLIO_00424	3.27e-112	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
CIKLKLIO_00425	3.46e-185	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
CIKLKLIO_00426	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
CIKLKLIO_00427	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CIKLKLIO_00429	8.67e-228	glkA	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
CIKLKLIO_00430	4e-117	-	-	-	K	-	-	-	Winged helix DNA-binding domain
CIKLKLIO_00431	6.22e-21	-	-	-	EGP	-	-	-	Major facilitator superfamily
CIKLKLIO_00432	5.53e-207	dkg	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
CIKLKLIO_00433	7.76e-89	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
CIKLKLIO_00434	2.4e-187	-	-	-	-	-	-	-	-
CIKLKLIO_00435	9.08e-135	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
CIKLKLIO_00437	6.44e-49	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
CIKLKLIO_00438	5.78e-247	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CIKLKLIO_00439	1.53e-210	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CIKLKLIO_00440	9.75e-17	-	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
CIKLKLIO_00441	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
CIKLKLIO_00442	4.33e-189	istB	-	-	L	-	-	-	IstB-like ATP binding protein
CIKLKLIO_00443	2.24e-241	-	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
CIKLKLIO_00444	1.85e-181	-	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
CIKLKLIO_00445	2.94e-239	-	-	-	U	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
CIKLKLIO_00446	6.71e-206	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
CIKLKLIO_00447	3.38e-159	livF	-	-	E	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_00448	2.92e-153	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
CIKLKLIO_00449	1.44e-276	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
CIKLKLIO_00450	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
CIKLKLIO_00451	3.86e-156	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CIKLKLIO_00452	0.0	-	-	-	L	-	-	-	PIF1-like helicase
CIKLKLIO_00453	3.53e-45	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Radical SAM superfamily
CIKLKLIO_00454	1.21e-124	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Radical SAM superfamily
CIKLKLIO_00455	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CIKLKLIO_00456	2.11e-148	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
CIKLKLIO_00457	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
CIKLKLIO_00458	2.91e-199	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
CIKLKLIO_00459	1.25e-192	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
CIKLKLIO_00460	5.8e-316	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
CIKLKLIO_00461	3.06e-219	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
CIKLKLIO_00462	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
CIKLKLIO_00463	2.59e-130	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CIKLKLIO_00464	8.56e-111	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
CIKLKLIO_00465	2.14e-257	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
CIKLKLIO_00466	3.16e-299	aspB	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
CIKLKLIO_00467	9.73e-228	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
CIKLKLIO_00468	2.01e-267	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
CIKLKLIO_00470	8.67e-101	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
CIKLKLIO_00471	3.3e-85	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CIKLKLIO_00472	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
CIKLKLIO_00473	3.71e-122	ywrO	-	-	S	-	-	-	Flavodoxin-like fold
CIKLKLIO_00474	1.02e-56	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CIKLKLIO_00475	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CIKLKLIO_00476	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
CIKLKLIO_00477	1.09e-172	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CIKLKLIO_00478	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
CIKLKLIO_00479	1.21e-191	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
CIKLKLIO_00480	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
CIKLKLIO_00481	5.49e-183	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIKLKLIO_00482	0.0	bgl2	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
CIKLKLIO_00483	3.08e-45	-	-	-	L	-	-	-	Transposase DDE domain
CIKLKLIO_00484	4.33e-189	istB	-	-	L	-	-	-	IstB-like ATP binding protein
CIKLKLIO_00485	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
CIKLKLIO_00486	4.93e-247	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
CIKLKLIO_00487	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CIKLKLIO_00488	1.22e-32	-	3.4.13.22	-	S	ko:K08641,ko:K11206	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
CIKLKLIO_00489	8.09e-131	-	3.4.13.22	-	S	ko:K08641,ko:K11206	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
CIKLKLIO_00490	1.79e-132	gat	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Amidase
CIKLKLIO_00491	1.35e-41	-	-	-	O	-	-	-	OsmC-like protein
CIKLKLIO_00492	4.15e-176	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
CIKLKLIO_00493	2.27e-276	-	-	-	U	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
CIKLKLIO_00494	0.0	-	3.2.1.40	-	E	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase C-terminal domain
CIKLKLIO_00495	7.39e-256	-	-	-	G	-	-	-	Transporter major facilitator family protein
CIKLKLIO_00496	2.63e-89	mgtC	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
CIKLKLIO_00497	4.12e-61	-	-	-	S	-	-	-	Nucleotidyltransferase domain
CIKLKLIO_00498	7.61e-93	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
CIKLKLIO_00499	3.32e-309	-	3.2.1.4, 3.2.1.58	GH5,GH9	G	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CIKLKLIO_00500	1.9e-46	-	-	-	-	-	-	-	-
CIKLKLIO_00501	3.26e-94	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIKLKLIO_00502	5.77e-206	-	-	-	G	-	-	-	Major Facilitator Superfamily
CIKLKLIO_00503	3.29e-312	-	-	-	S	ko:K06978	-	ko00000	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain
CIKLKLIO_00504	4.13e-141	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
CIKLKLIO_00505	1.14e-109	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIKLKLIO_00506	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
CIKLKLIO_00507	1.23e-117	-	-	-	K	-	-	-	MarR family
CIKLKLIO_00508	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
CIKLKLIO_00509	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
CIKLKLIO_00510	0.0	-	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CIKLKLIO_00511	6.46e-86	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
CIKLKLIO_00512	2.1e-180	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
CIKLKLIO_00513	9.06e-194	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_00514	7.8e-197	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_00515	3.65e-151	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
CIKLKLIO_00516	1.01e-227	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
CIKLKLIO_00517	2.34e-242	rihB	3.2.2.1, 3.2.2.8	-	F	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
CIKLKLIO_00518	2.51e-167	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
CIKLKLIO_00519	6.53e-291	bdhA	-	-	C	ko:K19955	-	ko00000,ko01000	Iron-containing alcohol dehydrogenase
CIKLKLIO_00520	2.84e-209	rbsK	2.7.1.15	-	G	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CIKLKLIO_00521	0.0	-	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
CIKLKLIO_00522	8.35e-49	-	-	-	L	ko:K07485	-	ko00000	Transposase
CIKLKLIO_00523	3.18e-237	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
CIKLKLIO_00524	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_00525	1.21e-210	rbsC	-	-	U	ko:K10439,ko:K10440	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
CIKLKLIO_00526	8.68e-207	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
CIKLKLIO_00527	3e-89	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	RbsD / FucU transport protein family
CIKLKLIO_00528	5.15e-224	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CIKLKLIO_00529	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CIKLKLIO_00530	4.88e-261	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CIKLKLIO_00531	5.64e-200	-	-	-	U	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_00532	5.9e-206	-	-	-	U	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_00533	2.94e-261	-	-	-	E	ko:K02052	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CIKLKLIO_00534	1.47e-203	-	-	-	I	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
CIKLKLIO_00536	0.0	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
CIKLKLIO_00537	9.48e-308	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
CIKLKLIO_00538	1.15e-47	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain protein
CIKLKLIO_00539	7.75e-37	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
CIKLKLIO_00540	0.000386	-	-	-	G	-	-	-	N-terminal domain of (some) glycogen debranching enzymes
CIKLKLIO_00541	4.33e-189	istB	-	-	L	-	-	-	IstB-like ATP binding protein
CIKLKLIO_00542	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
CIKLKLIO_00543	5.06e-47	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CIKLKLIO_00544	8.14e-97	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
CIKLKLIO_00545	0.0	-	-	-	K	-	-	-	Putative DNA-binding domain
CIKLKLIO_00546	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
CIKLKLIO_00548	6.71e-192	-	-	-	G	-	-	-	Fic/DOC family
CIKLKLIO_00549	5.83e-292	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CIKLKLIO_00550	5.45e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CIKLKLIO_00551	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
CIKLKLIO_00552	7.27e-242	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CIKLKLIO_00553	4.15e-169	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
CIKLKLIO_00554	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CIKLKLIO_00555	5.58e-152	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
CIKLKLIO_00556	3.4e-162	-	-	-	S	-	-	-	SNARE associated Golgi protein
CIKLKLIO_00557	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
CIKLKLIO_00558	1.63e-172	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
CIKLKLIO_00559	0.0	-	-	-	K	ko:K02538,ko:K03483,ko:K03491	-	ko00000,ko03000	PRD domain
CIKLKLIO_00560	3.14e-94	-	-	-	H	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CIKLKLIO_00561	4.66e-105	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CIKLKLIO_00562	2.2e-62	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CIKLKLIO_00563	2.79e-113	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
CIKLKLIO_00564	2.25e-66	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
CIKLKLIO_00565	1.57e-175	-	-	-	G	ko:K17195	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Ribulose-phosphate 3 epimerase family
CIKLKLIO_00566	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
CIKLKLIO_00567	4.8e-224	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
CIKLKLIO_00568	8.43e-16	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
CIKLKLIO_00569	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CIKLKLIO_00570	3.31e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
CIKLKLIO_00571	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
CIKLKLIO_00572	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
CIKLKLIO_00573	2.38e-140	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
CIKLKLIO_00574	0.0	-	-	-	S	-	-	-	PGAP1-like protein
CIKLKLIO_00575	8.64e-76	-	-	-	-	-	-	-	-
CIKLKLIO_00576	1.27e-214	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
CIKLKLIO_00577	2.52e-240	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
CIKLKLIO_00578	1.55e-117	-	-	-	-	-	-	-	-
CIKLKLIO_00579	9.35e-209	-	-	-	S	-	-	-	Protein of unknown function DUF58
CIKLKLIO_00580	1.53e-245	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
CIKLKLIO_00581	1.4e-169	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CIKLKLIO_00582	3.14e-115	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
CIKLKLIO_00583	7.33e-50	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
CIKLKLIO_00584	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CIKLKLIO_00585	6.57e-54	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
CIKLKLIO_00586	2.67e-148	-	-	-	-	-	-	-	-
CIKLKLIO_00587	1.23e-170	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
CIKLKLIO_00588	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
CIKLKLIO_00589	1.75e-87	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
CIKLKLIO_00590	4.74e-244	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
CIKLKLIO_00591	3.99e-231	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
CIKLKLIO_00592	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
CIKLKLIO_00593	7.57e-15	-	-	-	K	-	-	-	AraC-like ligand binding domain
CIKLKLIO_00594	2.31e-177	gtr	-	-	U	ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Sugar (and other) transporter
CIKLKLIO_00595	2.35e-67	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
CIKLKLIO_00596	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
CIKLKLIO_00597	1.39e-312	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
CIKLKLIO_00598	1.25e-261	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
CIKLKLIO_00599	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CIKLKLIO_00600	4.46e-132	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
CIKLKLIO_00601	9.45e-198	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
CIKLKLIO_00602	3.16e-189	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
CIKLKLIO_00603	8.52e-144	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_00604	1.49e-251	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_00605	0.0	-	-	-	I	-	-	-	PAP2 superfamily
CIKLKLIO_00606	6.56e-145	-	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
CIKLKLIO_00607	0.0	-	-	-	EK	ko:K05825,ko:K18907	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko00002,ko01000,ko01504,ko03000	Alanine-glyoxylate amino-transferase
CIKLKLIO_00609	2.54e-255	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
CIKLKLIO_00610	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
CIKLKLIO_00611	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
CIKLKLIO_00612	1.89e-13	mtrA	-	-	KT	ko:K07670	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
CIKLKLIO_00613	2.13e-40	mtrB	2.7.13.3	-	T	ko:K07636,ko:K07654	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
CIKLKLIO_00614	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CIKLKLIO_00615	6.97e-240	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
CIKLKLIO_00616	1.53e-61	-	-	-	-	-	-	-	-
CIKLKLIO_00617	2.1e-51	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
CIKLKLIO_00618	4.67e-63	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
CIKLKLIO_00619	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CIKLKLIO_00620	1.64e-133	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CIKLKLIO_00621	8.96e-252	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
CIKLKLIO_00622	4.17e-189	-	-	-	C	-	-	-	Putative TM nitroreductase
CIKLKLIO_00623	6.61e-181	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
CIKLKLIO_00624	0.0	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
CIKLKLIO_00625	1.8e-306	lacY	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
CIKLKLIO_00626	6.02e-231	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
CIKLKLIO_00627	0.0	-	-	-	O	ko:K13963	ko05146,map05146	ko00000,ko00001	SERine Proteinase INhibitors
CIKLKLIO_00628	8.19e-244	-	-	-	-	-	-	-	-
CIKLKLIO_00629	5.01e-159	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
CIKLKLIO_00630	9.67e-296	-	-	-	T	-	-	-	Histidine kinase
CIKLKLIO_00631	0.0	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
CIKLKLIO_00632	1.64e-81	-	-	-	S	-	-	-	Thiamine-binding protein
CIKLKLIO_00633	2.14e-187	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
CIKLKLIO_00634	4.08e-290	-	-	-	O	ko:K13525	ko04141,ko05134,map04141,map05134	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	AAA domain (Cdc48 subfamily)
CIKLKLIO_00635	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CIKLKLIO_00636	1.12e-197	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CIKLKLIO_00637	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
CIKLKLIO_00638	0.0	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CIKLKLIO_00639	8.65e-275	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CIKLKLIO_00640	2.98e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CIKLKLIO_00641	1.99e-59	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
CIKLKLIO_00642	1.2e-89	-	-	-	V	-	-	-	DivIVA protein
CIKLKLIO_00643	1.72e-116	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CIKLKLIO_00644	4.29e-227	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
CIKLKLIO_00645	2.13e-256	-	-	-	K	-	-	-	WYL domain
CIKLKLIO_00646	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
CIKLKLIO_00648	1.54e-214	dkgV	-	-	C	-	-	-	Aldo/keto reductase family
CIKLKLIO_00649	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
CIKLKLIO_00651	3.44e-211	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
CIKLKLIO_00652	3.92e-145	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
CIKLKLIO_00653	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
CIKLKLIO_00654	4.33e-189	istB	-	-	L	-	-	-	IstB-like ATP binding protein
CIKLKLIO_00655	2.61e-196	-	-	-	S	-	-	-	Amidohydrolase
CIKLKLIO_00656	8.54e-214	-	4.1.2.28	-	EM	ko:K22397	ko00040,map00040	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
CIKLKLIO_00657	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
CIKLKLIO_00658	1.84e-197	-	-	-	S	-	-	-	Aldo/keto reductase family
CIKLKLIO_00659	4.18e-71	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Acylphosphatase
CIKLKLIO_00660	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CIKLKLIO_00661	5.24e-278	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CIKLKLIO_00662	1.93e-143	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
CIKLKLIO_00663	2.17e-162	-	-	-	-	-	-	-	-
CIKLKLIO_00664	2.07e-155	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CIKLKLIO_00665	9.71e-167	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
CIKLKLIO_00666	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2252)
CIKLKLIO_00667	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
CIKLKLIO_00668	1.24e-279	-	-	-	EGP	ko:K18567,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
CIKLKLIO_00669	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
CIKLKLIO_00670	1.99e-159	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
CIKLKLIO_00671	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CIKLKLIO_00672	1.61e-225	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
CIKLKLIO_00673	2.8e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CIKLKLIO_00674	3.53e-156	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CIKLKLIO_00675	7.41e-70	-	-	-	M	-	-	-	Lysin motif
CIKLKLIO_00676	4.08e-101	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CIKLKLIO_00677	4.79e-292	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
CIKLKLIO_00678	0.0	-	-	-	L	-	-	-	DNA helicase
CIKLKLIO_00679	2.33e-120	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
CIKLKLIO_00680	2e-241	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CIKLKLIO_00681	9.1e-91	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CIKLKLIO_00682	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
CIKLKLIO_00683	2.6e-200	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CIKLKLIO_00684	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CIKLKLIO_00685	9.54e-265	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CIKLKLIO_00686	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CIKLKLIO_00687	4.07e-287	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
CIKLKLIO_00688	1.24e-278	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CIKLKLIO_00689	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
CIKLKLIO_00690	1.95e-229	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
CIKLKLIO_00692	1.74e-112	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CIKLKLIO_00693	8.97e-126	-	-	-	G	-	-	-	Major Facilitator Superfamily
CIKLKLIO_00694	1.66e-216	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
CIKLKLIO_00695	1.31e-287	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
CIKLKLIO_00696	2e-211	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
CIKLKLIO_00697	1.12e-266	-	-	-	GK	-	-	-	ROK family
CIKLKLIO_00698	9.44e-193	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CIKLKLIO_00699	5.02e-314	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
CIKLKLIO_00700	1.58e-127	-	-	-	F	-	-	-	NUDIX domain
CIKLKLIO_00701	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
CIKLKLIO_00702	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
CIKLKLIO_00703	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
CIKLKLIO_00704	2.16e-102	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
CIKLKLIO_00705	2.36e-246	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
CIKLKLIO_00706	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CIKLKLIO_00707	1.11e-176	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
CIKLKLIO_00708	3.96e-69	-	-	-	-	-	-	-	-
CIKLKLIO_00709	3.57e-235	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
CIKLKLIO_00710	4.21e-245	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
CIKLKLIO_00711	5.06e-234	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CIKLKLIO_00712	4.92e-115	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CIKLKLIO_00713	1.23e-252	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CIKLKLIO_00714	3.28e-174	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
CIKLKLIO_00715	5.41e-12	-	-	-	S	-	-	-	Spermine/spermidine synthase domain
CIKLKLIO_00716	1.72e-157	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CIKLKLIO_00717	2.72e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
CIKLKLIO_00718	7.76e-81	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CIKLKLIO_00719	7.67e-114	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
CIKLKLIO_00720	1.32e-206	-	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
CIKLKLIO_00721	2.14e-244	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
CIKLKLIO_00722	2.86e-201	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
CIKLKLIO_00723	2.93e-194	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
CIKLKLIO_00724	9.39e-195	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CIKLKLIO_00725	4.97e-147	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CIKLKLIO_00726	8.8e-202	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
CIKLKLIO_00727	0.0	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CIKLKLIO_00728	4.52e-142	nadB	1.4.3.16, 2.4.2.19	-	H	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
CIKLKLIO_00729	8.73e-202	nadB	1.4.3.16, 2.4.2.19	-	H	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
CIKLKLIO_00730	2.25e-209	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
CIKLKLIO_00731	1.58e-300	iscS1	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
CIKLKLIO_00732	4.83e-24	nanT	-	-	U	ko:K03290,ko:K08178,ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
CIKLKLIO_00733	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
CIKLKLIO_00734	5.21e-177	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_00735	1.46e-139	-	-	-	K	-	-	-	Virulence activator alpha C-term
CIKLKLIO_00736	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
CIKLKLIO_00737	3.85e-103	-	-	-	-	-	-	-	-
CIKLKLIO_00738	9.21e-241	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
CIKLKLIO_00739	4.06e-244	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
CIKLKLIO_00740	2.76e-55	-	-	-	-	-	-	-	-
CIKLKLIO_00741	1.23e-265	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
CIKLKLIO_00742	3.02e-302	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
CIKLKLIO_00743	1.06e-189	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIKLKLIO_00744	1.41e-240	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
CIKLKLIO_00745	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
CIKLKLIO_00746	1.39e-204	dppB	-	-	EP	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_00747	2.81e-233	dppC	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
CIKLKLIO_00748	0.0	-	-	-	EP	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
CIKLKLIO_00749	1.13e-217	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
CIKLKLIO_00750	6.9e-196	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
CIKLKLIO_00751	2.99e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
CIKLKLIO_00752	7.26e-304	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CIKLKLIO_00753	7.51e-127	-	-	-	-	-	-	-	-
CIKLKLIO_00754	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
CIKLKLIO_00755	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CIKLKLIO_00756	2.33e-155	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
CIKLKLIO_00757	2.37e-108	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
CIKLKLIO_00758	6.96e-176	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
CIKLKLIO_00759	5.96e-214	-	-	-	EG	-	-	-	EamA-like transporter family
CIKLKLIO_00760	1.99e-192	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
CIKLKLIO_00761	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CIKLKLIO_00762	6.92e-235	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CIKLKLIO_00763	2.34e-194	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
CIKLKLIO_00764	1.99e-304	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
CIKLKLIO_00765	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
CIKLKLIO_00766	5.95e-153	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CIKLKLIO_00767	5.61e-127	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
CIKLKLIO_00768	1.55e-99	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CIKLKLIO_00769	4.66e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
CIKLKLIO_00770	1.25e-263	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CIKLKLIO_00771	4.71e-135	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
CIKLKLIO_00772	6.14e-155	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CIKLKLIO_00773	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CIKLKLIO_00774	4.78e-248	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CIKLKLIO_00775	1.33e-158	-	-	-	-	-	-	-	-
CIKLKLIO_00776	2.4e-169	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
CIKLKLIO_00777	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
CIKLKLIO_00778	4.11e-252	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
CIKLKLIO_00779	6.88e-146	-	-	-	-	-	-	-	-
CIKLKLIO_00780	1.24e-248	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CIKLKLIO_00781	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
CIKLKLIO_00782	2.17e-285	-	-	-	G	-	-	-	Major Facilitator Superfamily
CIKLKLIO_00783	1.73e-220	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CIKLKLIO_00784	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
CIKLKLIO_00787	1.61e-27	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
CIKLKLIO_00788	8.31e-135	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
CIKLKLIO_00790	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
CIKLKLIO_00791	1.11e-298	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
CIKLKLIO_00792	3.04e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
CIKLKLIO_00793	4.95e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
CIKLKLIO_00794	5.02e-110	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
CIKLKLIO_00795	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CIKLKLIO_00796	1.1e-130	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CIKLKLIO_00797	2.17e-97	-	-	-	-	-	-	-	-
CIKLKLIO_00799	0.0	-	-	-	S	-	-	-	HipA-like C-terminal domain
CIKLKLIO_00800	9.51e-218	-	-	-	S	-	-	-	Fic/DOC family
CIKLKLIO_00801	2.79e-53	-	-	-	-	-	-	-	-
CIKLKLIO_00802	5.12e-19	intA	-	-	L	-	-	-	Phage integrase family
CIKLKLIO_00803	4.33e-189	istB	-	-	L	-	-	-	IstB-like ATP binding protein
CIKLKLIO_00804	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
CIKLKLIO_00805	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
CIKLKLIO_00806	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
CIKLKLIO_00807	5.09e-223	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
CIKLKLIO_00808	5.02e-155	-	-	-	G	ko:K02025,ko:K17330	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_00809	2.82e-160	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_00810	1.14e-278	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CIKLKLIO_00811	1.38e-173	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
CIKLKLIO_00812	1e-189	-	-	-	L	-	-	-	PFAM Integrase catalytic
CIKLKLIO_00813	1.23e-93	-	-	-	L	-	-	-	PFAM Integrase catalytic
CIKLKLIO_00814	2.73e-304	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
CIKLKLIO_00815	5.13e-119	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
CIKLKLIO_00817	2.31e-41	-	-	-	-	-	-	-	-
CIKLKLIO_00818	6.15e-170	-	-	-	C	-	-	-	Putative TM nitroreductase
CIKLKLIO_00819	1.22e-220	-	-	-	EG	-	-	-	EamA-like transporter family
CIKLKLIO_00820	3.34e-92	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
CIKLKLIO_00821	2.1e-296	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
CIKLKLIO_00822	2.1e-215	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
CIKLKLIO_00823	4.06e-217	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
CIKLKLIO_00824	6.18e-205	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
CIKLKLIO_00825	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
CIKLKLIO_00826	8.17e-84	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
CIKLKLIO_00827	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
CIKLKLIO_00828	5.05e-221	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
CIKLKLIO_00829	6.13e-112	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
CIKLKLIO_00830	1.45e-203	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
CIKLKLIO_00831	1.92e-134	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
CIKLKLIO_00832	1.09e-248	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CIKLKLIO_00840	5.18e-14	-	-	-	K	-	-	-	Helix-turn-helix domain
CIKLKLIO_00842	2.84e-38	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	VirC1 protein
CIKLKLIO_00844	6.12e-30	-	-	-	-	-	-	-	-
CIKLKLIO_00845	3.32e-45	-	-	-	-	-	-	-	-
CIKLKLIO_00846	1.73e-50	-	-	-	-	ko:K03646	-	ko00000,ko02000	-
CIKLKLIO_00847	0.0	-	-	-	D	-	-	-	Cell surface antigen C-terminus
CIKLKLIO_00850	6.94e-43	-	-	-	-	-	-	-	-
CIKLKLIO_00851	2.11e-40	-	-	-	-	-	-	-	-
CIKLKLIO_00852	1.02e-197	-	-	-	-	-	-	-	-
CIKLKLIO_00853	8.35e-235	-	-	-	-	-	-	-	-
CIKLKLIO_00854	2.52e-251	-	-	-	S	-	-	-	COG0433 Predicted ATPase
CIKLKLIO_00858	1e-28	-	-	-	-	-	-	-	-
CIKLKLIO_00859	3.17e-288	-	-	-	U	-	-	-	TraM recognition site of TraD and TraG
CIKLKLIO_00860	8.41e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4913)
CIKLKLIO_00861	5.46e-36	-	-	-	-	-	-	-	-
CIKLKLIO_00864	6.14e-35	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	Pfam:HipA_N
CIKLKLIO_00865	7.41e-180	-	-	-	L	-	-	-	PFAM Relaxase mobilization nuclease family protein
CIKLKLIO_00866	1.61e-76	-	-	-	S	-	-	-	Fic/DOC family
CIKLKLIO_00867	3.27e-63	-	-	-	L	-	-	-	EcoRII C terminal
CIKLKLIO_00869	8.47e-32	-	-	-	S	-	-	-	Pfam:CtkA_N
CIKLKLIO_00870	3.68e-21	-	-	-	K	-	-	-	Bacterial mobilisation protein (MobC)
CIKLKLIO_00873	8.56e-297	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
CIKLKLIO_00876	3.21e-86	-	-	-	-	-	-	-	-
CIKLKLIO_00877	7.47e-111	-	-	-	M	ko:K21688	-	ko00000	G5 domain protein
CIKLKLIO_00879	4.33e-189	istB	-	-	L	-	-	-	IstB-like ATP binding protein
CIKLKLIO_00880	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
CIKLKLIO_00882	1.44e-28	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
CIKLKLIO_00885	9.32e-122	-	-	-	S	-	-	-	Fic/DOC family
CIKLKLIO_00886	4.22e-112	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
CIKLKLIO_00887	4.68e-165	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
CIKLKLIO_00889	7.36e-222	-	-	-	L	-	-	-	Phage integrase family
CIKLKLIO_00891	2.35e-47	-	-	-	M	-	-	-	Peptidase family M23
CIKLKLIO_00892	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
CIKLKLIO_00893	8.16e-308	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
CIKLKLIO_00894	8.81e-264	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
CIKLKLIO_00895	5.83e-120	-	-	-	-	-	-	-	-
CIKLKLIO_00896	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
CIKLKLIO_00897	1.96e-113	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CIKLKLIO_00898	2.69e-192	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
CIKLKLIO_00899	5.35e-175	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CIKLKLIO_00900	3.81e-171	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
CIKLKLIO_00901	4.97e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CIKLKLIO_00902	8.23e-223	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
CIKLKLIO_00903	1.36e-286	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CIKLKLIO_00904	1.61e-91	-	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
CIKLKLIO_00905	4.13e-180	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CIKLKLIO_00906	2.28e-93	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CIKLKLIO_00907	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CIKLKLIO_00908	1.8e-84	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
CIKLKLIO_00909	3.67e-231	-	-	-	-	-	-	-	-
CIKLKLIO_00910	8.67e-101	-	-	-	-	-	-	-	-
CIKLKLIO_00911	7.04e-82	-	-	-	K	-	-	-	Protein of unknown function, DUF488
CIKLKLIO_00912	5.66e-13	-	-	-	-	-	-	-	-
CIKLKLIO_00913	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
CIKLKLIO_00914	1.77e-27	-	-	-	G	-	-	-	Major facilitator Superfamily
CIKLKLIO_00915	2.62e-55	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CIKLKLIO_00916	1.32e-45	hipA	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	kinase activity
CIKLKLIO_00917	2.36e-61	-	-	-	K	ko:K20391	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
CIKLKLIO_00918	9.37e-142	-	-	-	-	-	-	-	-
CIKLKLIO_00919	1.31e-32	-	-	-	-	-	-	-	-
CIKLKLIO_00921	2.23e-156	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_00922	3.51e-165	-	-	-	-	-	-	-	-
CIKLKLIO_00923	5.85e-133	-	-	-	-	-	-	-	-
CIKLKLIO_00924	2.76e-191	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
CIKLKLIO_00925	3.95e-82	-	-	-	-	-	-	-	-
CIKLKLIO_00926	3.5e-93	-	-	-	-	-	-	-	-
CIKLKLIO_00927	2.73e-207	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
CIKLKLIO_00928	2.87e-173	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
CIKLKLIO_00929	3.55e-139	-	-	-	-	-	-	-	-
CIKLKLIO_00931	6.57e-125	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
CIKLKLIO_00933	8.87e-66	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
CIKLKLIO_00934	1.27e-54	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
CIKLKLIO_00935	7.81e-235	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
CIKLKLIO_00936	7.99e-119	-	-	-	Q	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_00937	2.91e-200	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CIKLKLIO_00938	5.1e-125	-	-	-	-	-	-	-	-
CIKLKLIO_00939	3.69e-166	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
CIKLKLIO_00940	3.3e-261	-	-	-	T	-	-	-	Histidine kinase
CIKLKLIO_00941	6.56e-19	-	-	-	T	-	-	-	Histidine kinase
CIKLKLIO_00944	1.39e-155	-	-	-	-	-	-	-	-
CIKLKLIO_00945	1.5e-65	-	-	-	-	-	-	-	-
CIKLKLIO_00946	1.1e-129	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
CIKLKLIO_00947	7.7e-81	cefD	5.1.1.17	-	E	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Aminotransferase, class V
CIKLKLIO_00948	2.96e-241	-	-	-	V	-	-	-	VanZ like family
CIKLKLIO_00949	4.07e-76	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CIKLKLIO_00950	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
CIKLKLIO_00951	3.3e-200	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CIKLKLIO_00952	3.05e-169	-	-	-	S	-	-	-	SOS response associated peptidase (SRAP)
CIKLKLIO_00953	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CIKLKLIO_00954	7.23e-207	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
CIKLKLIO_00955	5.51e-240	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CIKLKLIO_00956	7.16e-155	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
CIKLKLIO_00957	5.07e-56	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
CIKLKLIO_00958	3.05e-200	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
CIKLKLIO_00959	9.77e-64	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CIKLKLIO_00960	7.29e-220	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
CIKLKLIO_00961	6.08e-61	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
CIKLKLIO_00962	2.17e-179	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
CIKLKLIO_00963	2.02e-97	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
CIKLKLIO_00964	3.04e-141	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CIKLKLIO_00965	4.37e-84	-	-	-	-	-	-	-	-
CIKLKLIO_00966	2.44e-50	-	-	-	-	-	-	-	-
CIKLKLIO_00967	2.61e-179	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
CIKLKLIO_00968	3.18e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
CIKLKLIO_00969	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
CIKLKLIO_00970	4.22e-70	-	-	-	-	-	-	-	-
CIKLKLIO_00971	0.0	-	-	-	K	-	-	-	WYL domain
CIKLKLIO_00972	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
CIKLKLIO_00973	2.75e-210	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CIKLKLIO_00975	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
CIKLKLIO_00976	1.57e-184	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
CIKLKLIO_00977	1.34e-181	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
CIKLKLIO_00978	2.5e-43	-	-	-	-	-	-	-	-
CIKLKLIO_00979	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
CIKLKLIO_00980	3.41e-297	-	-	-	-	-	-	-	-
CIKLKLIO_00981	1.03e-208	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CIKLKLIO_00982	1.2e-281	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
CIKLKLIO_00983	3.21e-130	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CIKLKLIO_00984	2.53e-71	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
CIKLKLIO_00985	1.5e-254	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CIKLKLIO_00986	4.14e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CIKLKLIO_00987	4.21e-131	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CIKLKLIO_00988	1.19e-156	yebC	-	-	K	-	-	-	transcriptional regulatory protein
CIKLKLIO_00989	2.77e-145	-	2.7.7.53	-	FG	ko:K19710	ko00230,map00230	ko00000,ko00001,ko01000	HIT domain
CIKLKLIO_00990	1.07e-121	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CIKLKLIO_00991	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CIKLKLIO_00997	4.38e-169	-	-	-	S	-	-	-	PAC2 family
CIKLKLIO_00998	1.51e-201	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CIKLKLIO_00999	7.54e-200	-	-	-	G	-	-	-	Fructosamine kinase
CIKLKLIO_01000	2.51e-31	-	-	-	L	-	-	-	Phage integrase family
CIKLKLIO_01001	4.33e-189	istB	-	-	L	-	-	-	IstB-like ATP binding protein
CIKLKLIO_01002	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
CIKLKLIO_01003	2.91e-99	-	-	-	L	-	-	-	Phage integrase family
CIKLKLIO_01004	1.36e-29	-	-	-	N	-	-	-	HicA toxin of bacterial toxin-antitoxin,
CIKLKLIO_01005	8.78e-18	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0150
CIKLKLIO_01008	1.08e-73	-	-	-	-	-	-	-	-
CIKLKLIO_01009	7.48e-150	-	-	-	S	-	-	-	Virulence protein RhuM family
CIKLKLIO_01010	3.34e-09	-	-	-	-	-	-	-	-
CIKLKLIO_01018	8.99e-65	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
CIKLKLIO_01021	2e-96	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
CIKLKLIO_01023	1.9e-84	-	-	-	V	-	-	-	HNH endonuclease
CIKLKLIO_01025	3.43e-45	-	-	-	A	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CIKLKLIO_01031	6.19e-115	-	-	-	J	-	-	-	tRNA 5'-leader removal
CIKLKLIO_01032	3.6e-38	-	-	-	K	-	-	-	Transcriptional regulator
CIKLKLIO_01035	8.49e-69	-	-	-	-	ko:K07451	-	ko00000,ko01000,ko02048	-
CIKLKLIO_01036	5.81e-119	-	-	-	-	-	-	-	-
CIKLKLIO_01037	1.02e-286	-	-	-	S	-	-	-	Terminase
CIKLKLIO_01038	5e-125	-	-	-	S	-	-	-	Terminase
CIKLKLIO_01039	4.44e-209	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
CIKLKLIO_01040	4.62e-124	-	-	-	-	-	-	-	-
CIKLKLIO_01041	1.18e-28	-	-	-	-	-	-	-	-
CIKLKLIO_01042	1.29e-99	-	-	-	S	-	-	-	P22 coat protein-protein 5 domain protein
CIKLKLIO_01043	1.72e-77	-	-	-	-	-	-	-	-
CIKLKLIO_01044	8.89e-69	-	-	-	-	-	-	-	-
CIKLKLIO_01045	2.28e-50	-	-	-	-	-	-	-	-
CIKLKLIO_01046	2.16e-53	-	-	-	-	-	-	-	-
CIKLKLIO_01047	6.16e-105	-	-	-	-	-	-	-	-
CIKLKLIO_01048	1.67e-73	-	-	-	-	-	-	-	-
CIKLKLIO_01049	6.46e-46	-	-	-	-	-	-	-	-
CIKLKLIO_01050	3.13e-244	-	-	-	S	-	-	-	Phage-related minor tail protein
CIKLKLIO_01051	2.97e-59	-	-	-	-	-	-	-	-
CIKLKLIO_01052	1.58e-43	-	-	-	-	-	-	-	-
CIKLKLIO_01053	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
CIKLKLIO_01054	4.33e-189	istB	-	-	L	-	-	-	IstB-like ATP binding protein
CIKLKLIO_01056	3.67e-161	-	-	-	-	-	-	-	-
CIKLKLIO_01057	1.43e-39	-	-	-	D	ko:K21449	-	ko00000,ko02000	nuclear chromosome segregation
CIKLKLIO_01058	1.55e-36	-	-	-	-	-	-	-	-
CIKLKLIO_01059	1.45e-79	-	-	-	-	-	-	-	-
CIKLKLIO_01060	1.91e-108	-	-	-	V	-	-	-	N-acetylmuramoyl-L-alanine amidase
CIKLKLIO_01061	1.03e-24	-	-	-	-	-	-	-	-
CIKLKLIO_01062	3.92e-92	-	-	-	OU	-	-	-	Serine dehydrogenase proteinase
CIKLKLIO_01064	2.29e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CIKLKLIO_01065	4.04e-244	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CIKLKLIO_01066	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
CIKLKLIO_01067	2.71e-259	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CIKLKLIO_01068	1.49e-307	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
CIKLKLIO_01069	9.16e-251	-	-	-	-	-	-	-	-
CIKLKLIO_01070	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
CIKLKLIO_01071	5.98e-207	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CIKLKLIO_01072	1.68e-225	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
CIKLKLIO_01073	2.51e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
CIKLKLIO_01074	4.18e-189	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CIKLKLIO_01075	1.3e-281	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
CIKLKLIO_01076	2.86e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
CIKLKLIO_01077	3.82e-229	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
CIKLKLIO_01078	1.78e-241	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
CIKLKLIO_01079	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CIKLKLIO_01080	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CIKLKLIO_01081	5.6e-294	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
CIKLKLIO_01082	4.49e-19	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
CIKLKLIO_01083	2.36e-64	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CIKLKLIO_01084	3.85e-60	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CIKLKLIO_01085	3.69e-168	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
CIKLKLIO_01086	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
CIKLKLIO_01087	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CIKLKLIO_01088	1.93e-157	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
CIKLKLIO_01089	1.55e-221	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
CIKLKLIO_01090	3.01e-275	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
CIKLKLIO_01091	8.87e-39	-	-	-	-	-	-	-	-
CIKLKLIO_01092	4.64e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CIKLKLIO_01093	1.7e-233	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CIKLKLIO_01094	2.25e-202	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
CIKLKLIO_01095	6.06e-224	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
CIKLKLIO_01096	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CIKLKLIO_01097	2.61e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
CIKLKLIO_01098	8.93e-229	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
CIKLKLIO_01099	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
CIKLKLIO_01100	8.46e-240	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CIKLKLIO_01101	9.57e-209	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
CIKLKLIO_01102	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CIKLKLIO_01104	1.38e-127	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
CIKLKLIO_01105	4.3e-255	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CIKLKLIO_01106	1.45e-170	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
CIKLKLIO_01108	4.16e-181	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CIKLKLIO_01109	1.99e-187	-	-	-	S	-	-	-	phosphoesterase or phosphohydrolase
CIKLKLIO_01110	1.16e-118	lppD	-	-	S	-	-	-	Appr-1'-p processing enzyme
CIKLKLIO_01111	1.68e-227	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CIKLKLIO_01112	2.82e-31	-	-	-	L	-	-	-	Transposase, Mutator family
CIKLKLIO_01113	1.04e-182	-	-	-	-	-	-	-	-
CIKLKLIO_01114	1.47e-136	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
CIKLKLIO_01117	2.06e-49	-	-	-	K	ko:K03088	-	ko00000,ko03021	Psort location Cytoplasmic, score
CIKLKLIO_01118	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
CIKLKLIO_01119	4.33e-189	istB	-	-	L	-	-	-	IstB-like ATP binding protein
CIKLKLIO_01120	1.86e-45	-	-	-	K	ko:K03088	-	ko00000,ko03021	Psort location Cytoplasmic, score 8.96
CIKLKLIO_01122	7.27e-207	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CIKLKLIO_01123	1.2e-176	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_01124	4.78e-312	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
CIKLKLIO_01125	1.02e-107	-	-	-	-	-	-	-	-
CIKLKLIO_01126	0.0	-	-	-	S	-	-	-	Glycosyl hydrolases related to GH101 family, GH129
CIKLKLIO_01127	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
CIKLKLIO_01129	4.63e-71	-	-	-	T	-	-	-	Histidine kinase
CIKLKLIO_01130	1.14e-78	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
CIKLKLIO_01131	4.72e-54	-	-	-	-	-	-	-	-
CIKLKLIO_01133	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
CIKLKLIO_01134	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
CIKLKLIO_01135	6.71e-77	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
CIKLKLIO_01136	1.59e-243	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
CIKLKLIO_01138	0.0	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
CIKLKLIO_01139	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CIKLKLIO_01140	4.75e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
CIKLKLIO_01141	4.82e-179	-	-	-	S	-	-	-	UPF0126 domain
CIKLKLIO_01142	6.23e-189	mazG	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	Psort location Cytoplasmic, score 8.87
CIKLKLIO_01143	2.72e-288	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
CIKLKLIO_01144	2.59e-137	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CIKLKLIO_01145	3.57e-299	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
CIKLKLIO_01146	1.27e-309	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CIKLKLIO_01147	3.55e-58	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
CIKLKLIO_01148	1.99e-262	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
CIKLKLIO_01149	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
CIKLKLIO_01150	3.7e-234	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CIKLKLIO_01151	0.0	corC	-	-	S	-	-	-	CBS domain
CIKLKLIO_01152	9.01e-132	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CIKLKLIO_01153	9.79e-278	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
CIKLKLIO_01154	2.76e-76	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
CIKLKLIO_01155	1.48e-183	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CIKLKLIO_01157	3.21e-211	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
CIKLKLIO_01158	1.6e-309	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CIKLKLIO_01159	2.19e-142	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
CIKLKLIO_01160	6.85e-132	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
CIKLKLIO_01161	1.07e-303	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CIKLKLIO_01162	2.81e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
CIKLKLIO_01163	4.34e-301	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
CIKLKLIO_01164	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
CIKLKLIO_01165	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
CIKLKLIO_01166	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CIKLKLIO_01167	2.86e-102	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
CIKLKLIO_01168	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CIKLKLIO_01169	1.06e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CIKLKLIO_01170	7.1e-91	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
CIKLKLIO_01171	3.24e-256	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CIKLKLIO_01172	2.12e-99	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CIKLKLIO_01173	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CIKLKLIO_01174	6.59e-48	-	-	-	-	-	-	-	-
CIKLKLIO_01175	5.96e-77	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
CIKLKLIO_01176	2.43e-166	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
CIKLKLIO_01177	2.55e-65	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
CIKLKLIO_01178	3.14e-87	-	-	-	T	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
CIKLKLIO_01179	5.99e-143	-	-	-	E	-	-	-	Transglutaminase-like superfamily
CIKLKLIO_01180	7.72e-70	-	-	-	S	-	-	-	SdpI/YhfL protein family
CIKLKLIO_01181	5.2e-118	-	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	cytidine deaminase activity
CIKLKLIO_01182	1.47e-200	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
CIKLKLIO_01183	5.26e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CIKLKLIO_01184	3.43e-207	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
CIKLKLIO_01185	1.89e-276	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
CIKLKLIO_01186	3.79e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
CIKLKLIO_01187	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
CIKLKLIO_01188	3.1e-137	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CIKLKLIO_01189	4.45e-309	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
CIKLKLIO_01190	6.32e-42	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
CIKLKLIO_01191	1.11e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
CIKLKLIO_01192	3.08e-204	-	-	-	I	-	-	-	Serine aminopeptidase, S33
CIKLKLIO_01193	6.26e-218	-	-	-	M	-	-	-	pfam nlp p60
CIKLKLIO_01194	2.51e-137	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
CIKLKLIO_01195	1.4e-140	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
CIKLKLIO_01196	7.13e-261	-	-	-	-	-	-	-	-
CIKLKLIO_01197	6.13e-52	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
CIKLKLIO_01198	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
CIKLKLIO_01199	0.0	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
CIKLKLIO_01200	1.36e-284	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
CIKLKLIO_01201	7.53e-239	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_01202	1.41e-118	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
CIKLKLIO_01203	2.21e-234	-	-	-	T	-	-	-	Histidine kinase
CIKLKLIO_01204	5.73e-52	-	-	-	T	-	-	-	Histidine kinase
CIKLKLIO_01205	3.4e-146	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
CIKLKLIO_01206	4.53e-146	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
CIKLKLIO_01207	3.07e-242	pitB	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
CIKLKLIO_01208	0.0	nplT	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
CIKLKLIO_01209	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
CIKLKLIO_01210	2.42e-298	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
CIKLKLIO_01211	3.47e-207	-	-	-	G	-	-	-	Phosphoglycerate mutase family
CIKLKLIO_01212	1.54e-137	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
CIKLKLIO_01213	2.08e-301	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
CIKLKLIO_01214	2.38e-83	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CIKLKLIO_01215	3.07e-118	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
CIKLKLIO_01216	2.26e-37	-	-	-	L	-	-	-	Helix-turn-helix domain
CIKLKLIO_01217	6.91e-30	-	-	-	L	-	-	-	Helix-turn-helix domain
CIKLKLIO_01218	2.15e-155	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
CIKLKLIO_01219	0.0	-	-	-	C	ko:K06871	-	ko00000	Iron-sulfur cluster-binding domain
CIKLKLIO_01220	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
CIKLKLIO_01221	2.13e-286	gtr	-	-	U	ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Sugar (and other) transporter
CIKLKLIO_01222	4.91e-204	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
CIKLKLIO_01223	5.28e-282	-	-	-	GK	-	-	-	ROK family
CIKLKLIO_01224	2.11e-223	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
CIKLKLIO_01225	6.11e-189	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CIKLKLIO_01226	1.53e-307	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
CIKLKLIO_01227	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CIKLKLIO_01228	1.45e-17	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
CIKLKLIO_01229	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
CIKLKLIO_01230	2.7e-17	-	-	-	-	-	-	-	-
CIKLKLIO_01231	1.37e-78	yccF	-	-	S	-	-	-	Inner membrane component domain
CIKLKLIO_01232	4.66e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CIKLKLIO_01233	9.65e-143	glnP2	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_01234	2.26e-153	glnP	-	-	E	ko:K02029,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_01235	7.78e-177	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATP binding protein of ABC transporter for glutamate aspartate K02028
CIKLKLIO_01236	5.28e-201	glnH	-	-	ET	ko:K02030,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
CIKLKLIO_01237	2.3e-190	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CIKLKLIO_01238	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
CIKLKLIO_01239	0.0	-	-	-	T	-	-	-	Histidine kinase
CIKLKLIO_01240	2.03e-180	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
CIKLKLIO_01241	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
CIKLKLIO_01242	4.4e-217	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIKLKLIO_01243	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
CIKLKLIO_01244	2.26e-210	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
CIKLKLIO_01245	4.32e-29	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
CIKLKLIO_01246	8.76e-99	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
CIKLKLIO_01247	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
CIKLKLIO_01248	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
CIKLKLIO_01249	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
CIKLKLIO_01250	3.43e-234	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
CIKLKLIO_01251	2.38e-148	safC	-	-	S	-	-	-	O-methyltransferase
CIKLKLIO_01252	2.76e-216	fmt2	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
CIKLKLIO_01253	6.11e-311	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CIKLKLIO_01254	3.19e-307	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
CIKLKLIO_01257	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CIKLKLIO_01258	1.56e-156	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CIKLKLIO_01259	2.96e-151	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CIKLKLIO_01260	1.3e-78	-	-	-	-	-	-	-	-
CIKLKLIO_01261	1.06e-313	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
CIKLKLIO_01262	3.47e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CIKLKLIO_01263	0.0	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
CIKLKLIO_01264	5.51e-153	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
CIKLKLIO_01265	5.19e-222	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CIKLKLIO_01266	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
CIKLKLIO_01267	1.5e-52	-	-	-	-	-	-	-	-
CIKLKLIO_01268	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CIKLKLIO_01269	1.19e-286	-	-	-	S	-	-	-	Peptidase dimerisation domain
CIKLKLIO_01270	3.9e-146	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_01271	1.15e-279	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CIKLKLIO_01272	1.27e-225	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
CIKLKLIO_01273	1.15e-200	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CIKLKLIO_01276	7.2e-174	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
CIKLKLIO_01277	5.45e-86	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CIKLKLIO_01278	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CIKLKLIO_01279	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
CIKLKLIO_01280	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
CIKLKLIO_01281	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
CIKLKLIO_01282	6.79e-245	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CIKLKLIO_01284	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
CIKLKLIO_01285	3.27e-295	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CIKLKLIO_01286	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CIKLKLIO_01287	3.26e-274	-	-	-	-	-	-	-	-
CIKLKLIO_01288	1.06e-155	-	-	-	-	-	-	-	-
CIKLKLIO_01290	1.12e-28	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
CIKLKLIO_01292	5.95e-160	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
CIKLKLIO_01293	1.43e-115	-	-	-	K	-	-	-	Putative zinc ribbon domain
CIKLKLIO_01294	1.09e-34	zntR	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CIKLKLIO_01295	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
CIKLKLIO_01296	1.15e-161	-	-	-	L	-	-	-	NUDIX domain
CIKLKLIO_01297	4.64e-227	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
CIKLKLIO_01298	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CIKLKLIO_01299	1.77e-168	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
CIKLKLIO_01301	1.12e-142	aspA	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
CIKLKLIO_01302	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
CIKLKLIO_01303	3.81e-228	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
CIKLKLIO_01304	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CIKLKLIO_01305	2.16e-148	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CIKLKLIO_01306	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
CIKLKLIO_01307	1.53e-209	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CIKLKLIO_01308	3.27e-258	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
CIKLKLIO_01309	1.29e-206	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_01310	7.76e-175	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
CIKLKLIO_01311	2.52e-114	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
CIKLKLIO_01312	2.16e-130	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
CIKLKLIO_01313	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CIKLKLIO_01314	3.51e-164	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
CIKLKLIO_01315	1.43e-249	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
CIKLKLIO_01316	9.12e-159	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
CIKLKLIO_01317	2.92e-190	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
CIKLKLIO_01318	1.23e-100	-	-	-	S	-	-	-	Zincin-like metallopeptidase
CIKLKLIO_01319	0.0	-	-	-	-	-	-	-	-
CIKLKLIO_01320	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
CIKLKLIO_01321	2.06e-74	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
CIKLKLIO_01322	3.93e-291	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
CIKLKLIO_01323	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
CIKLKLIO_01324	8.13e-62	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
CIKLKLIO_01325	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
CIKLKLIO_01326	7.86e-198	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
CIKLKLIO_01327	4.05e-75	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CIKLKLIO_01328	9.56e-97	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
CIKLKLIO_01329	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
CIKLKLIO_01330	1.72e-123	-	-	-	-	-	-	-	-
CIKLKLIO_01332	5.24e-233	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
CIKLKLIO_01333	4.79e-134	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
CIKLKLIO_01334	4.64e-114	-	-	-	D	-	-	-	Septum formation initiator
CIKLKLIO_01335	2.49e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CIKLKLIO_01336	2.75e-213	-	-	-	C	-	-	-	Aldo/keto reductase family
CIKLKLIO_01337	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CIKLKLIO_01338	4.23e-147	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CIKLKLIO_01339	6.7e-121	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
CIKLKLIO_01340	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
CIKLKLIO_01341	4.09e-20	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
CIKLKLIO_01342	5.15e-116	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
CIKLKLIO_01343	1.1e-177	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CIKLKLIO_01344	1.26e-124	-	-	-	-	-	-	-	-
CIKLKLIO_01345	1.34e-299	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CIKLKLIO_01346	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
CIKLKLIO_01347	1.45e-52	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
CIKLKLIO_01348	4.33e-189	istB	-	-	L	-	-	-	IstB-like ATP binding protein
CIKLKLIO_01349	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
CIKLKLIO_01350	2.31e-75	-	-	-	S	-	-	-	ABC-2 family transporter protein
CIKLKLIO_01351	1.94e-155	-	-	-	S	-	-	-	ABC-2 family transporter protein
CIKLKLIO_01352	6.07e-223	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_01353	3.46e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
CIKLKLIO_01354	3.12e-72	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
CIKLKLIO_01355	2.23e-150	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
CIKLKLIO_01356	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
CIKLKLIO_01357	1.11e-235	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CIKLKLIO_01359	5.33e-89	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
CIKLKLIO_01360	1.89e-151	-	-	-	-	-	-	-	-
CIKLKLIO_01361	1.49e-178	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
CIKLKLIO_01363	4.64e-255	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
CIKLKLIO_01364	7.76e-295	-	-	-	L	-	-	-	Tetratricopeptide repeat
CIKLKLIO_01365	0.0	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CIKLKLIO_01366	1.41e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
CIKLKLIO_01367	9.39e-181	-	-	-	S	-	-	-	Putative ABC-transporter type IV
CIKLKLIO_01368	6.92e-133	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
CIKLKLIO_01369	6.08e-93	-	-	-	P	-	-	-	Rhodanese Homology Domain
CIKLKLIO_01370	1.14e-188	thiF	2.7.7.73, 2.7.7.80, 2.8.1.11	-	H	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
CIKLKLIO_01371	5.92e-201	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
CIKLKLIO_01372	3.55e-39	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
CIKLKLIO_01373	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
CIKLKLIO_01374	1.62e-44	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
CIKLKLIO_01375	1.72e-58	-	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
CIKLKLIO_01376	7.47e-103	-	-	-	L	-	-	-	PFAM Integrase catalytic
CIKLKLIO_01377	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
CIKLKLIO_01378	4.33e-189	istB	-	-	L	-	-	-	IstB-like ATP binding protein
CIKLKLIO_01379	1.2e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
CIKLKLIO_01380	2.51e-109	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
CIKLKLIO_01381	4.85e-232	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CIKLKLIO_01382	3.98e-314	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
CIKLKLIO_01383	1.96e-225	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
CIKLKLIO_01384	3.37e-272	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CIKLKLIO_01385	1.34e-258	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CIKLKLIO_01386	5.13e-137	-	-	-	-	-	-	-	-
CIKLKLIO_01387	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
CIKLKLIO_01388	4.35e-258	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CIKLKLIO_01389	7.79e-203	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CIKLKLIO_01390	7.69e-204	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
CIKLKLIO_01391	0.0	ykoD	-	-	P	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_01392	4.38e-140	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
CIKLKLIO_01393	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
CIKLKLIO_01394	4.43e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
CIKLKLIO_01395	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CIKLKLIO_01396	6.85e-181	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
CIKLKLIO_01397	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
CIKLKLIO_01398	3.32e-263	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
CIKLKLIO_01399	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CIKLKLIO_01400	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
CIKLKLIO_01401	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CIKLKLIO_01403	3.25e-181	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_01404	4.23e-288	-	-	-	E	-	-	-	Aminotransferase class I and II
CIKLKLIO_01405	2.17e-243	-	-	-	P	-	-	-	NMT1/THI5 like
CIKLKLIO_01406	2.46e-173	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_01407	1.58e-197	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CIKLKLIO_01408	6.84e-166	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
CIKLKLIO_01409	0.0	-	-	-	I	-	-	-	acetylesterase activity
CIKLKLIO_01410	1.09e-292	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CIKLKLIO_01411	1.77e-281	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
CIKLKLIO_01412	3.93e-301	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
CIKLKLIO_01414	2.42e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
CIKLKLIO_01415	2.12e-210	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
CIKLKLIO_01416	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
CIKLKLIO_01417	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
CIKLKLIO_01418	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
CIKLKLIO_01419	3.25e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
CIKLKLIO_01420	1.8e-215	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
CIKLKLIO_01421	3.96e-165	-	-	-	S	-	-	-	Vitamin K epoxide reductase
CIKLKLIO_01422	1.87e-218	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
CIKLKLIO_01423	3.84e-189	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
CIKLKLIO_01424	2.34e-203	-	-	-	S	-	-	-	Patatin-like phospholipase
CIKLKLIO_01425	9.87e-19	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
CIKLKLIO_01426	5.7e-31	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
CIKLKLIO_01427	1.79e-170	hflK	-	-	O	-	-	-	prohibitin homologues
CIKLKLIO_01428	1.41e-11	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
CIKLKLIO_01429	1.09e-55	-	-	-	O	-	-	-	Glutaredoxin
CIKLKLIO_01430	6.38e-298	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
CIKLKLIO_01431	2.07e-161	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
CIKLKLIO_01432	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
CIKLKLIO_01433	7.75e-07	-	-	-	-	-	-	-	-
CIKLKLIO_01434	7.2e-175	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
CIKLKLIO_01435	2.64e-135	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
CIKLKLIO_01436	2.65e-217	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
CIKLKLIO_01437	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
CIKLKLIO_01438	4.37e-308	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
CIKLKLIO_01439	1.24e-121	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CIKLKLIO_01440	6.57e-136	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CIKLKLIO_01441	1.89e-166	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_01442	6.03e-176	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
CIKLKLIO_01443	0.0	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
CIKLKLIO_01444	0.0	-	3.2.1.14	GH18	S	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Carbohydrate binding domain
CIKLKLIO_01445	0.0	-	-	-	M	-	-	-	probably involved in cell wall
CIKLKLIO_01447	1.21e-62	-	4.1.1.44	-	L	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
CIKLKLIO_01448	6.54e-161	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
CIKLKLIO_01449	1.37e-52	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
CIKLKLIO_01450	3.5e-149	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
CIKLKLIO_01451	0.000113	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
CIKLKLIO_01452	6.31e-159	-	-	-	L	ko:K07457	-	ko00000	endonuclease III
CIKLKLIO_01453	2.3e-310	-	-	-	V	-	-	-	MatE
CIKLKLIO_01454	2.48e-279	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CIKLKLIO_01455	4.14e-300	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CIKLKLIO_01456	1.7e-140	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
CIKLKLIO_01457	9.78e-192	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
CIKLKLIO_01458	8.02e-106	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
CIKLKLIO_01459	1.27e-247	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
CIKLKLIO_01460	1.45e-98	-	-	-	K	-	-	-	MerR family regulatory protein
CIKLKLIO_01461	3.66e-115	-	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CIKLKLIO_01462	3.93e-78	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CIKLKLIO_01463	1.36e-42	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
CIKLKLIO_01464	1.19e-235	-	-	-	S	-	-	-	Conserved hypothetical protein 698
CIKLKLIO_01465	1.49e-185	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
CIKLKLIO_01466	1.8e-165	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
CIKLKLIO_01467	4.1e-293	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CIKLKLIO_01468	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CIKLKLIO_01469	1.9e-104	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CIKLKLIO_01470	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CIKLKLIO_01471	3.25e-142	-	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
CIKLKLIO_01473	4.1e-250	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
CIKLKLIO_01474	9.06e-279	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
CIKLKLIO_01475	4.45e-292	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
CIKLKLIO_01476	6.66e-298	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CIKLKLIO_01477	4.83e-176	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
CIKLKLIO_01478	2.65e-225	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
CIKLKLIO_01479	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
CIKLKLIO_01480	1.45e-314	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CIKLKLIO_01481	0.0	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
CIKLKLIO_01482	4.82e-147	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
CIKLKLIO_01483	8.33e-187	-	-	-	-	-	-	-	-
CIKLKLIO_01484	6.15e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
CIKLKLIO_01488	5.39e-132	nnrE	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
CIKLKLIO_01489	1.12e-16	-	-	-	C	-	-	-	Aldo/keto reductase family
CIKLKLIO_01490	1.4e-44	-	-	-	-	-	-	-	-
CIKLKLIO_01491	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
CIKLKLIO_01492	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CIKLKLIO_01493	3.72e-239	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
CIKLKLIO_01494	1.48e-309	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
CIKLKLIO_01495	0.0	aldH	1.2.1.3, 1.2.99.10	-	C	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase family
CIKLKLIO_01496	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
CIKLKLIO_01497	8.45e-210	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
CIKLKLIO_01498	7.59e-05	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	50S ribosomal protein L31
CIKLKLIO_01499	2.8e-256	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
CIKLKLIO_01500	1.14e-179	-	-	-	S	-	-	-	TIGRFAM TIGR03943 family protein
CIKLKLIO_01501	1.36e-111	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Ferric uptake regulator family
CIKLKLIO_01502	9.84e-85	-	-	-	-	-	-	-	-
CIKLKLIO_01503	4.25e-91	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
CIKLKLIO_01504	1.29e-33	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
CIKLKLIO_01505	8.58e-97	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
CIKLKLIO_01506	7.7e-95	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
CIKLKLIO_01507	1.41e-285	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CIKLKLIO_01508	1.46e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CIKLKLIO_01509	3.27e-230	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
CIKLKLIO_01510	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CIKLKLIO_01511	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
CIKLKLIO_01512	1.11e-249	-	-	-	M	-	-	-	Conserved repeat domain
CIKLKLIO_01513	6.56e-184	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_01514	5.37e-112	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	peptide-methionine (S)-S-oxide reductase activity
CIKLKLIO_01515	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
CIKLKLIO_01517	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
CIKLKLIO_01518	9.75e-295	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
CIKLKLIO_01519	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
CIKLKLIO_01522	7.51e-204	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
CIKLKLIO_01523	3.54e-50	-	-	-	G	-	-	-	Alpha-L-arabinofuranosidase C-terminal domain
CIKLKLIO_01524	9.8e-41	-	-	-	-	-	-	-	-
CIKLKLIO_01525	4.75e-268	-	-	-	P	-	-	-	Citrate transporter
CIKLKLIO_01526	0.0	-	-	-	EK	ko:K03710,ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000,ko03000	Alanine-glyoxylate amino-transferase
CIKLKLIO_01527	1.4e-147	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CIKLKLIO_01528	1.63e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CIKLKLIO_01529	1.92e-46	-	-	-	-	-	-	-	-
CIKLKLIO_01530	5.04e-90	-	-	-	S	-	-	-	PIN domain
CIKLKLIO_01531	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CIKLKLIO_01532	1.19e-309	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
CIKLKLIO_01533	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CIKLKLIO_01534	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
CIKLKLIO_01535	4.31e-133	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CIKLKLIO_01536	4.78e-120	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CIKLKLIO_01537	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
CIKLKLIO_01538	2.15e-281	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
CIKLKLIO_01539	2.02e-245	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
CIKLKLIO_01540	3.37e-177	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_01541	1.13e-176	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
CIKLKLIO_01542	2.8e-198	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_01543	6.69e-216	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_01544	7.49e-122	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
CIKLKLIO_01545	4.73e-232	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
CIKLKLIO_01546	1.29e-183	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CIKLKLIO_01547	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
CIKLKLIO_01548	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
CIKLKLIO_01549	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
CIKLKLIO_01550	2.47e-226	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
CIKLKLIO_01551	2.55e-216	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_01552	3.73e-239	-	-	-	K	-	-	-	Periplasmic binding protein domain
CIKLKLIO_01553	1.77e-180	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
CIKLKLIO_01554	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CIKLKLIO_01555	3.69e-193	tcyC	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_01556	3.78e-223	yecS	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_01557	1.86e-216	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
CIKLKLIO_01558	6.96e-198	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
CIKLKLIO_01559	3.26e-106	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CIKLKLIO_01560	2.5e-210	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
CIKLKLIO_01561	1.9e-206	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
CIKLKLIO_01562	6.5e-269	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
CIKLKLIO_01563	2.52e-263	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CIKLKLIO_01564	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
CIKLKLIO_01565	5.28e-159	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CIKLKLIO_01566	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CIKLKLIO_01567	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
CIKLKLIO_01568	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CIKLKLIO_01569	2.06e-208	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CIKLKLIO_01570	2.77e-171	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CIKLKLIO_01571	5.5e-300	-	-	-	G	-	-	-	Major Facilitator Superfamily
CIKLKLIO_01572	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
CIKLKLIO_01573	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
CIKLKLIO_01574	2.51e-283	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
CIKLKLIO_01575	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
CIKLKLIO_01576	5.59e-309	-	-	-	S	-	-	-	Protein of unknown function DUF58
CIKLKLIO_01577	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
CIKLKLIO_01578	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIKLKLIO_01579	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIKLKLIO_01580	1.56e-165	-	-	-	-	-	-	-	-
CIKLKLIO_01581	1.59e-209	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
CIKLKLIO_01582	3.37e-148	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CIKLKLIO_01583	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
CIKLKLIO_01584	7.93e-59	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
CIKLKLIO_01585	6.15e-299	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
CIKLKLIO_01586	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
CIKLKLIO_01587	3.61e-158	-	-	-	K	-	-	-	DeoR C terminal sensor domain
CIKLKLIO_01588	8.83e-289	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
CIKLKLIO_01589	1.22e-305	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
CIKLKLIO_01590	0.0	pon1	-	-	M	-	-	-	Transglycosylase
CIKLKLIO_01591	2.7e-172	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
CIKLKLIO_01592	4.98e-281	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
CIKLKLIO_01593	2.09e-244	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
CIKLKLIO_01594	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
CIKLKLIO_01595	4.05e-284	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
CIKLKLIO_01596	1.26e-91	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
CIKLKLIO_01597	5.94e-282	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
CIKLKLIO_01598	2e-204	-	-	-	I	-	-	-	Alpha/beta hydrolase family
CIKLKLIO_01599	7.47e-156	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
CIKLKLIO_01600	5.55e-79	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
CIKLKLIO_01601	5.99e-220	-	-	-	S	ko:K21688	-	ko00000	G5
CIKLKLIO_01602	5.99e-265	-	-	-	-	-	-	-	-
CIKLKLIO_01603	1.15e-314	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
CIKLKLIO_01604	2.47e-92	-	-	-	-	-	-	-	-
CIKLKLIO_01605	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
CIKLKLIO_01606	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
CIKLKLIO_01607	5.05e-188	istB	-	-	L	-	-	-	IstB-like ATP binding protein
CIKLKLIO_01608	7.64e-57	-	-	-	L	-	-	-	Transposase
CIKLKLIO_01609	2.82e-193	-	-	-	L	-	-	-	IstB-like ATP binding protein
CIKLKLIO_01611	3.91e-246	-	-	-	G	-	-	-	Acyltransferase family
CIKLKLIO_01612	3.6e-137	-	-	-	S	-	-	-	EpsG family
CIKLKLIO_01614	3.88e-239	-	-	-	M	-	-	-	Glycosyltransferase like family 2
CIKLKLIO_01615	1.42e-271	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
CIKLKLIO_01616	3.84e-171	-	-	-	H	-	-	-	Hexapeptide repeat of succinyl-transferase
CIKLKLIO_01617	2.3e-254	-	-	-	M	-	-	-	Glycosyltransferase like family 2
CIKLKLIO_01618	0.0	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
CIKLKLIO_01619	4.64e-314	-	-	-	M	ko:K00713	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferases group 1
CIKLKLIO_01620	2.25e-263	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Psort location Cytoplasmic, score 8.87
CIKLKLIO_01621	2.17e-141	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
CIKLKLIO_01622	1.11e-291	rfbP	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
CIKLKLIO_01623	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
CIKLKLIO_01624	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
CIKLKLIO_01625	5.52e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
CIKLKLIO_01626	1.83e-181	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
CIKLKLIO_01627	7.6e-213	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
CIKLKLIO_01628	0.0	galA	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	Glycosyl hydrolase family 53
CIKLKLIO_01629	2.63e-242	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
CIKLKLIO_01630	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
CIKLKLIO_01631	2.47e-226	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
CIKLKLIO_01632	5.75e-220	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_01633	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
CIKLKLIO_01634	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
CIKLKLIO_01636	7.13e-28	-	-	-	U	ko:K02100	-	ko00000,ko02000	Sugar (and other) transporter
CIKLKLIO_01637	1.28e-48	-	-	-	U	ko:K02100	-	ko00000,ko02000	Sugar (and other) transporter
CIKLKLIO_01638	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
CIKLKLIO_01639	5.57e-270	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
CIKLKLIO_01640	3.88e-204	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CIKLKLIO_01641	7.66e-222	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
CIKLKLIO_01642	9.65e-79	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CIKLKLIO_01644	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_01645	0.0	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_01646	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
CIKLKLIO_01649	7.64e-226	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
CIKLKLIO_01650	5.36e-172	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CIKLKLIO_01651	4.49e-185	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CIKLKLIO_01652	1.89e-316	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CIKLKLIO_01653	5.52e-152	-	-	-	-	-	-	-	-
CIKLKLIO_01654	4.29e-101	-	-	-	K	-	-	-	MerR, DNA binding
CIKLKLIO_01655	7.62e-248	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
CIKLKLIO_01656	2.31e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
CIKLKLIO_01657	9.97e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CIKLKLIO_01658	3.24e-159	-	-	-	-	-	-	-	-
CIKLKLIO_01659	1.59e-150	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
CIKLKLIO_01660	4.87e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
CIKLKLIO_01661	6.09e-173	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CIKLKLIO_01662	8.78e-176	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
CIKLKLIO_01663	2.71e-264	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
CIKLKLIO_01664	1.66e-119	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
CIKLKLIO_01665	1.52e-57	-	-	-	S	ko:K21495	-	ko00000,ko02048	Plasmid stability protein
CIKLKLIO_01666	9.42e-95	vapC	-	-	S	ko:K07062	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module. An RNase
CIKLKLIO_01667	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
CIKLKLIO_01668	1.15e-130	dam	2.1.1.72	-	H	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
CIKLKLIO_01669	8.3e-140	-	-	-	-	-	-	-	-
CIKLKLIO_01671	6.21e-174	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
CIKLKLIO_01672	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
CIKLKLIO_01673	2.72e-208	-	-	-	P	-	-	-	Cation efflux family
CIKLKLIO_01674	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CIKLKLIO_01675	2.21e-269	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
CIKLKLIO_01676	9.48e-85	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
CIKLKLIO_01677	1.02e-46	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
CIKLKLIO_01678	8.91e-139	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CIKLKLIO_01679	6.12e-257	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
CIKLKLIO_01680	1e-216	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
CIKLKLIO_01681	1.42e-28	-	-	-	-	-	-	-	-
CIKLKLIO_01682	3.33e-84	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
CIKLKLIO_01683	2.49e-77	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
CIKLKLIO_01684	7.84e-61	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
CIKLKLIO_01685	1.47e-13	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
CIKLKLIO_01686	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
CIKLKLIO_01687	4.3e-120	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
CIKLKLIO_01688	3.29e-102	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
CIKLKLIO_01689	7e-153	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIKLKLIO_01690	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
CIKLKLIO_01691	3.16e-134	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
CIKLKLIO_01692	2.04e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CIKLKLIO_01693	2.26e-145	-	-	-	-	-	-	-	-
CIKLKLIO_01695	1.08e-66	-	-	-	-	-	-	-	-
CIKLKLIO_01697	0.0	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
CIKLKLIO_01698	0.0	-	-	-	Q	-	-	-	von Willebrand factor (vWF) type A domain
CIKLKLIO_01699	4.77e-143	-	-	-	-	-	-	-	-
CIKLKLIO_01701	1.3e-146	-	-	-	P	-	-	-	Sodium/hydrogen exchanger family
CIKLKLIO_01702	1.66e-103	ams	2.4.1.4	GH13	G	ko:K05341	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
CIKLKLIO_01703	6.35e-104	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CIKLKLIO_01704	8.88e-112	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CIKLKLIO_01705	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
CIKLKLIO_01706	2.34e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIKLKLIO_01707	4.4e-69	-	-	-	L	-	-	-	Transposase DDE domain
CIKLKLIO_01708	1.15e-259	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CIKLKLIO_01709	5.26e-300	-	-	-	S	ko:K07133	-	ko00000	AAA domain
CIKLKLIO_01710	2.29e-227	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_01711	1.85e-211	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_01712	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
CIKLKLIO_01713	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
CIKLKLIO_01714	2.02e-247	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
CIKLKLIO_01715	0.0	-	-	-	C	ko:K06871	-	ko00000	Iron-sulfur cluster-binding domain
CIKLKLIO_01716	1.41e-172	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
CIKLKLIO_01718	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
CIKLKLIO_01719	3.77e-175	-	-	-	M	-	-	-	Mechanosensitive ion channel
CIKLKLIO_01720	2.15e-238	-	-	-	S	-	-	-	CAAX protease self-immunity
CIKLKLIO_01721	2.63e-302	-	-	-	E	ko:K02052	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CIKLKLIO_01722	1.18e-198	-	-	-	U	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_01723	9.78e-207	-	-	-	U	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_01724	8.7e-278	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CIKLKLIO_01725	7.06e-292	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
CIKLKLIO_01726	3.39e-229	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
CIKLKLIO_01727	4.4e-232	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
CIKLKLIO_01728	3.27e-83	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
CIKLKLIO_01731	9.16e-151	-	-	-	S	-	-	-	CYTH
CIKLKLIO_01732	4.21e-218	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
CIKLKLIO_01733	2.69e-231	-	-	-	-	-	-	-	-
CIKLKLIO_01734	7.84e-245	-	-	-	-	-	-	-	-
CIKLKLIO_01735	5.97e-215	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
CIKLKLIO_01736	3.01e-166	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CIKLKLIO_01737	2.1e-64	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
CIKLKLIO_01738	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CIKLKLIO_01739	1.2e-209	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CIKLKLIO_01740	1.84e-55	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CIKLKLIO_01741	5.29e-271	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CIKLKLIO_01742	1.83e-194	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CIKLKLIO_01743	1.43e-100	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CIKLKLIO_01744	1.42e-39	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CIKLKLIO_01745	7.18e-192	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
CIKLKLIO_01746	8.61e-264	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CIKLKLIO_01748	0.0	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
CIKLKLIO_01749	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
CIKLKLIO_01750	1.95e-119	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CIKLKLIO_01751	9.55e-127	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
CIKLKLIO_01752	7.63e-156	-	-	-	-	-	-	-	-
CIKLKLIO_01753	2.67e-179	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
CIKLKLIO_01754	6.93e-162	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CIKLKLIO_01755	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
CIKLKLIO_01756	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CIKLKLIO_01757	0.0	-	-	-	S	-	-	-	domain protein
CIKLKLIO_01758	7.71e-82	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
CIKLKLIO_01759	8.06e-156	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
CIKLKLIO_01760	7.65e-146	araQ	-	-	U	ko:K02026,ko:K10190,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_01761	5.07e-159	-	-	-	P	ko:K10189,ko:K10241	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_01762	1.83e-185	araN	-	-	G	ko:K10188	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CIKLKLIO_01763	1.25e-44	-	-	-	K	-	-	-	AraC-like ligand binding domain
CIKLKLIO_01764	5.91e-180	-	-	-	L	ko:K07485	-	ko00000	Transposase
CIKLKLIO_01765	6.12e-47	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	Amino-transferase class IV
CIKLKLIO_01767	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CIKLKLIO_01768	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
CIKLKLIO_01769	2.66e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
CIKLKLIO_01770	2.37e-248	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
CIKLKLIO_01771	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CIKLKLIO_01772	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CIKLKLIO_01773	7.57e-68	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CIKLKLIO_01775	7.3e-70	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
CIKLKLIO_01776	7.63e-229	-	-	-	-	-	-	-	-
CIKLKLIO_01777	5.76e-215	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
CIKLKLIO_01778	1.41e-215	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
CIKLKLIO_01779	4.16e-143	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CIKLKLIO_01780	2.18e-275	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
CIKLKLIO_01781	1.64e-57	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
CIKLKLIO_01782	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
CIKLKLIO_01783	2.45e-161	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
CIKLKLIO_01785	4.72e-92	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
CIKLKLIO_01786	2.15e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CIKLKLIO_01787	5.8e-109	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
CIKLKLIO_01788	2.77e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
CIKLKLIO_01789	3.31e-238	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CIKLKLIO_01790	3.01e-197	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CIKLKLIO_01791	0.0	-	3.2.1.185	GH127	S	ko:K09955,ko:K18205	-	ko00000,ko01000	Beta-L-arabinofuranosidase, GH127
CIKLKLIO_01792	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
CIKLKLIO_01793	1.06e-51	-	-	-	S	-	-	-	granule-associated protein
CIKLKLIO_01794	4.49e-181	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
CIKLKLIO_01795	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
CIKLKLIO_01796	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
CIKLKLIO_01797	8.96e-307	dinF	-	-	V	-	-	-	MatE
CIKLKLIO_01798	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
CIKLKLIO_01799	1.27e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
CIKLKLIO_01800	1.12e-304	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
CIKLKLIO_01801	3.4e-233	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CIKLKLIO_01802	1.23e-194	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIKLKLIO_01803	2.29e-253	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
CIKLKLIO_01804	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
CIKLKLIO_01806	0.0	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
CIKLKLIO_01807	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CIKLKLIO_01808	1.04e-247	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
CIKLKLIO_01809	2.39e-191	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
CIKLKLIO_01810	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CIKLKLIO_01811	0.0	-	-	-	S	-	-	-	Putative ABC-transporter type IV
CIKLKLIO_01812	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
CIKLKLIO_01813	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
CIKLKLIO_01814	6.6e-130	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
CIKLKLIO_01815	1.68e-102	-	-	-	S	-	-	-	FMN_bind
CIKLKLIO_01816	1.39e-187	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CIKLKLIO_01817	1.15e-277	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
CIKLKLIO_01818	8.58e-290	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
CIKLKLIO_01819	4.29e-293	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
CIKLKLIO_01820	1.89e-159	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
CIKLKLIO_01821	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
CIKLKLIO_01823	0.0	intA	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
CIKLKLIO_01824	8.39e-38	-	-	-	-	-	-	-	-
CIKLKLIO_01825	0.0	-	-	-	T	-	-	-	AAA domain
CIKLKLIO_01826	0.0	-	-	-	S	-	-	-	FRG domain
CIKLKLIO_01827	8.26e-294	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
CIKLKLIO_01828	1.13e-222	-	-	-	S	-	-	-	Domain of unknown function (DUF4928)
CIKLKLIO_01830	4.33e-189	istB	-	-	L	-	-	-	IstB-like ATP binding protein
CIKLKLIO_01831	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
CIKLKLIO_01832	2.07e-182	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
CIKLKLIO_01833	9.08e-131	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
CIKLKLIO_01834	5.28e-105	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
CIKLKLIO_01835	7.15e-73	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
CIKLKLIO_01836	8.38e-177	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
CIKLKLIO_01837	8.81e-103	-	-	-	-	-	-	-	-
CIKLKLIO_01840	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CIKLKLIO_01842	1.69e-232	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
CIKLKLIO_01843	2.09e-288	-	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
CIKLKLIO_01844	1.73e-205	-	-	-	-	-	-	-	-
CIKLKLIO_01845	1.19e-156	-	-	-	G	-	-	-	Phosphoglycerate mutase family
CIKLKLIO_01846	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CIKLKLIO_01847	1.29e-124	-	-	-	S	-	-	-	GtrA-like protein
CIKLKLIO_01848	9.13e-81	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
CIKLKLIO_01849	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
CIKLKLIO_01850	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
CIKLKLIO_01851	1.52e-137	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
CIKLKLIO_01854	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CIKLKLIO_01856	1.47e-50	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
CIKLKLIO_01857	3.67e-137	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
CIKLKLIO_01858	3.21e-266	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
CIKLKLIO_01859	5.84e-150	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CIKLKLIO_01860	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CIKLKLIO_01861	1.41e-221	-	-	-	I	-	-	-	PAP2 superfamily
CIKLKLIO_01862	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
CIKLKLIO_01863	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CIKLKLIO_01864	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
CIKLKLIO_01865	3.99e-196	-	-	-	K	-	-	-	FCD
CIKLKLIO_01866	4.61e-307	-	-	-	P	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
CIKLKLIO_01867	0.0	neu	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
CIKLKLIO_01868	9.97e-18	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
CIKLKLIO_01869	3.03e-189	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CIKLKLIO_01870	4.18e-228	nanA	4.1.3.3, 4.3.3.7	-	EM	ko:K01639,ko:K01714	ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
CIKLKLIO_01871	2.91e-189	oppF	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
CIKLKLIO_01872	0.0	oppCD2	-	-	EP	ko:K02031,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
CIKLKLIO_01873	2.11e-204	oppB6	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_01874	0.0	oppA7	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
CIKLKLIO_01875	8.8e-14	oppA7	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
CIKLKLIO_01876	1.8e-204	-	3.5.1.106	-	I	ko:K15357	ko00760,ko01120,map00760,map01120	ko00000,ko00001,ko00002,ko01000	carboxylic ester hydrolase activity
CIKLKLIO_01877	1.2e-162	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CIKLKLIO_01878	1.18e-226	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
CIKLKLIO_01879	1.22e-220	-	-	-	L	-	-	-	Domain of unknown function (DUF4862)
CIKLKLIO_01880	1.64e-143	-	-	-	-	-	-	-	-
CIKLKLIO_01881	1.94e-271	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CIKLKLIO_01882	2.87e-126	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
CIKLKLIO_01883	6.3e-174	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
CIKLKLIO_01884	3.96e-225	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
CIKLKLIO_01885	3.69e-47	-	-	-	V	-	-	-	Abi-like protein
CIKLKLIO_01886	9.62e-271	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
CIKLKLIO_01887	9.94e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CIKLKLIO_01888	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
CIKLKLIO_01889	9.4e-126	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CIKLKLIO_01890	1.33e-275	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
CIKLKLIO_01891	3.01e-70	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
CIKLKLIO_01892	2.92e-75	-	-	-	U	-	-	-	TadE-like protein
CIKLKLIO_01893	3.68e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
CIKLKLIO_01894	3.27e-149	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
CIKLKLIO_01895	1.47e-94	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
CIKLKLIO_01896	6.24e-244	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
CIKLKLIO_01897	7.5e-159	-	-	-	D	-	-	-	bacterial-type flagellum organization
CIKLKLIO_01898	9.04e-172	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
CIKLKLIO_01899	2.23e-163	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
CIKLKLIO_01900	9.22e-181	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
CIKLKLIO_01901	6.78e-143	-	-	-	C	-	-	-	Acyl-CoA reductase (LuxC)
CIKLKLIO_01902	5.43e-21	-	-	-	F	-	-	-	Psort location CytoplasmicMembrane, score 10.00
CIKLKLIO_01903	5.76e-134	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
CIKLKLIO_01904	2.45e-224	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
CIKLKLIO_01905	8.72e-115	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CIKLKLIO_01906	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
CIKLKLIO_01907	0.0	-	3.2.1.1, 3.2.1.41	CBM48,GH13	M	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	Aamy_C
CIKLKLIO_01908	1.37e-248	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
CIKLKLIO_01909	8.04e-188	traX	-	-	S	-	-	-	TraX protein
CIKLKLIO_01910	1.57e-207	malG	-	-	G	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_01911	0.0	malC	-	-	G	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CIKLKLIO_01912	2.41e-299	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CIKLKLIO_01913	0.0	malL	2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16	GH13,GH31	G	ko:K01187,ko:K05341,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
CIKLKLIO_01914	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
CIKLKLIO_01915	5.58e-221	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
CIKLKLIO_01916	0.0	-	-	-	M	-	-	-	domain protein
CIKLKLIO_01917	0.0	-	-	-	M	-	-	-	cell wall anchor domain protein
CIKLKLIO_01918	2.24e-239	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
CIKLKLIO_01919	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
CIKLKLIO_01920	1.76e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CIKLKLIO_01921	7.18e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CIKLKLIO_01922	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
CIKLKLIO_01923	1.21e-242	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
CIKLKLIO_01924	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
CIKLKLIO_01925	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
CIKLKLIO_01927	5.68e-258	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
CIKLKLIO_01928	5.18e-81	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CIKLKLIO_01929	2.64e-205	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CIKLKLIO_01930	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
CIKLKLIO_01931	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CIKLKLIO_01932	2.68e-253	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
CIKLKLIO_01933	1.09e-223	-	-	-	EG	-	-	-	EamA-like transporter family
CIKLKLIO_01935	3e-222	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
CIKLKLIO_01936	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
CIKLKLIO_01937	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
CIKLKLIO_01938	3.66e-120	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
CIKLKLIO_01939	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
CIKLKLIO_01940	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CIKLKLIO_01942	3.51e-191	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
CIKLKLIO_01943	8.66e-70	-	-	-	S	-	-	-	Putative heavy-metal-binding
CIKLKLIO_01944	2.73e-97	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
CIKLKLIO_01945	0.0	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
CIKLKLIO_01946	1.21e-137	-	-	-	M	-	-	-	Glycosyltransferase like family 2
CIKLKLIO_01947	3.33e-58	-	-	-	M	-	-	-	Glycosyltransferase like family 2
CIKLKLIO_01948	1.97e-254	-	-	-	S	-	-	-	Fic/DOC family
CIKLKLIO_01949	5.23e-171	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
CIKLKLIO_01950	4.46e-257	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CIKLKLIO_01951	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
CIKLKLIO_01952	0.0	-	-	-	S	-	-	-	Putative esterase
CIKLKLIO_01953	2.73e-37	-	-	-	-	-	-	-	-
CIKLKLIO_01954	1.62e-228	-	-	-	EG	-	-	-	EamA-like transporter family
CIKLKLIO_01955	4.94e-119	-	-	-	O	-	-	-	Hsp20/alpha crystallin family
CIKLKLIO_01956	5.35e-271	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
CIKLKLIO_01957	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
CIKLKLIO_01958	2.91e-228	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
CIKLKLIO_01959	8.7e-166	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
CIKLKLIO_01960	1.09e-105	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
CIKLKLIO_01961	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
CIKLKLIO_01962	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
CIKLKLIO_01963	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
CIKLKLIO_01964	5.61e-224	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
CIKLKLIO_01965	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
CIKLKLIO_01966	7.81e-155	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
CIKLKLIO_01967	9.28e-291	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
CIKLKLIO_01968	5.3e-154	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
CIKLKLIO_01969	2.41e-101	crgA	-	-	D	-	-	-	Involved in cell division
CIKLKLIO_01971	4.18e-179	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
CIKLKLIO_01972	1.46e-47	-	-	-	-	-	-	-	-
CIKLKLIO_01973	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CIKLKLIO_01974	1.75e-93	-	-	-	I	-	-	-	Sterol carrier protein
CIKLKLIO_01975	1.4e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
CIKLKLIO_01976	5.93e-261	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
CIKLKLIO_01977	0.0	-	-	-	S	-	-	-	Amidohydrolase family
CIKLKLIO_01978	7.23e-238	-	-	-	S	-	-	-	Protein conserved in bacteria
CIKLKLIO_01979	0.0	-	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CIKLKLIO_01980	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
CIKLKLIO_01981	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CIKLKLIO_01982	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
CIKLKLIO_01983	1.5e-160	-	-	-	S	ko:K07133	-	ko00000	AAA domain
CIKLKLIO_01984	0.0	-	3.1.4.52	-	T	ko:K14051	ko02024,ko02026,map02024,map02026	ko00000,ko00001,ko01000	Putative diguanylate phosphodiesterase
CIKLKLIO_01985	2.97e-143	-	-	-	S	-	-	-	Domain of unknown function (DUF4956)
CIKLKLIO_01986	1.93e-203	-	-	-	P	-	-	-	VTC domain
CIKLKLIO_01987	0.0	-	-	-	M	ko:K06330	-	ko00000	CotH kinase protein
CIKLKLIO_01988	0.0	-	-	-	S	ko:K21012	ko02025,map02025	ko00000,ko00001	Putative exopolysaccharide Exporter (EPS-E)
CIKLKLIO_01989	0.0	-	-	GT4	M	ko:K21011	ko02025,map02025	ko00000,ko00001,ko01003	Domain of unknown function (DUF3492)
CIKLKLIO_01990	4.77e-265	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
CIKLKLIO_01991	3.46e-114	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
CIKLKLIO_01992	2.92e-204	-	-	-	-	-	-	-	-
CIKLKLIO_01993	3.19e-61	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	ADP-glyceromanno-heptose 6-epimerase activity
CIKLKLIO_01994	0.0	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	ADP-glyceromanno-heptose 6-epimerase activity
CIKLKLIO_01995	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
CIKLKLIO_01996	1.68e-138	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
CIKLKLIO_01997	1.05e-154	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
CIKLKLIO_01998	6.23e-266	-	-	-	S	-	-	-	AAA ATPase domain
CIKLKLIO_01999	5.81e-306	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
CIKLKLIO_02000	1.81e-108	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
CIKLKLIO_02001	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
CIKLKLIO_02003	2.54e-159	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
CIKLKLIO_02006	3.64e-252	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
CIKLKLIO_02007	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
CIKLKLIO_02009	4.53e-264	-	-	-	V	-	-	-	VanZ like family
CIKLKLIO_02010	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
CIKLKLIO_02012	7.16e-233	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
CIKLKLIO_02013	6.05e-89	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
CIKLKLIO_02014	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CIKLKLIO_02015	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CIKLKLIO_02016	3.41e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
CIKLKLIO_02017	3.75e-255	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CIKLKLIO_02018	5.94e-262	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria