ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HPKLIDJL_00001 9.49e-317 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HPKLIDJL_00002 4.35e-262 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HPKLIDJL_00003 1.45e-46 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
HPKLIDJL_00004 3.04e-259 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HPKLIDJL_00005 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPKLIDJL_00006 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPKLIDJL_00007 6.02e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HPKLIDJL_00008 6.56e-165 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HPKLIDJL_00009 1.33e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HPKLIDJL_00010 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HPKLIDJL_00011 2.63e-99 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HPKLIDJL_00012 4.28e-309 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HPKLIDJL_00013 7.28e-267 - - - E - - - Major Facilitator Superfamily
HPKLIDJL_00014 8.32e-66 - - - - - - - -
HPKLIDJL_00015 6.22e-243 - - - L ko:K07482 - ko00000 Helix-turn-helix domain
HPKLIDJL_00018 3.69e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HPKLIDJL_00019 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HPKLIDJL_00020 2.55e-306 yycH - - S - - - YycH protein
HPKLIDJL_00021 3.39e-184 yycI - - S - - - YycH protein
HPKLIDJL_00022 5.49e-197 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
HPKLIDJL_00023 1.44e-264 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
HPKLIDJL_00024 4.11e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HPKLIDJL_00025 3.03e-94 ywnA - - K - - - Transcriptional regulator
HPKLIDJL_00026 2.68e-224 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HPKLIDJL_00027 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HPKLIDJL_00028 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HPKLIDJL_00029 7.69e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HPKLIDJL_00030 1.54e-144 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 transmembrane transport
HPKLIDJL_00031 1.04e-244 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPKLIDJL_00032 1.1e-232 - - - D ko:K06889 - ko00000 Alpha beta
HPKLIDJL_00033 1.02e-233 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPKLIDJL_00034 1.62e-276 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HPKLIDJL_00035 4.71e-47 - - - - - - - -
HPKLIDJL_00036 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
HPKLIDJL_00037 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPKLIDJL_00038 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HPKLIDJL_00039 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HPKLIDJL_00040 1.04e-209 - - - C - - - Aldo keto reductase
HPKLIDJL_00041 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
HPKLIDJL_00042 3.67e-86 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
HPKLIDJL_00043 3.05e-242 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HPKLIDJL_00044 4.61e-166 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HPKLIDJL_00045 1.77e-119 - - - K - - - transcriptional regulator
HPKLIDJL_00046 2.81e-212 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HPKLIDJL_00047 2.03e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HPKLIDJL_00048 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HPKLIDJL_00049 8.04e-124 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HPKLIDJL_00050 9.7e-168 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HPKLIDJL_00051 6.19e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HPKLIDJL_00052 1.98e-21 - - - C - - - C4-dicarboxylate transmembrane transporter activity
HPKLIDJL_00053 7.91e-125 - - - L ko:K07497 - ko00000 hmm pf00665
HPKLIDJL_00054 9.53e-110 - - - L - - - Helix-turn-helix domain
HPKLIDJL_00055 3.97e-62 - - - - - - - -
HPKLIDJL_00056 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HPKLIDJL_00057 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
HPKLIDJL_00058 2.71e-197 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HPKLIDJL_00059 2.73e-241 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPKLIDJL_00060 3.68e-142 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HPKLIDJL_00061 2.12e-275 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HPKLIDJL_00062 1.14e-311 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPKLIDJL_00063 1.83e-106 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
HPKLIDJL_00064 1.32e-307 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HPKLIDJL_00065 3.78e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPKLIDJL_00066 3.06e-304 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
HPKLIDJL_00067 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPKLIDJL_00068 9.8e-09 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
HPKLIDJL_00069 1.03e-105 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_00070 2e-304 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_00071 2.13e-277 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HPKLIDJL_00072 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
HPKLIDJL_00073 3.66e-315 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HPKLIDJL_00075 1.2e-240 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HPKLIDJL_00077 1.62e-287 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HPKLIDJL_00078 4.66e-177 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HPKLIDJL_00079 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HPKLIDJL_00080 6.99e-305 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_00081 1.03e-105 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_00082 4.76e-290 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HPKLIDJL_00083 1.09e-272 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
HPKLIDJL_00084 2.31e-185 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
HPKLIDJL_00085 2.9e-170 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HPKLIDJL_00086 1.01e-203 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HPKLIDJL_00087 2.15e-188 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HPKLIDJL_00088 6e-41 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
HPKLIDJL_00089 1.75e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HPKLIDJL_00090 1.48e-171 - - - S - - - Protein of unknown function (DUF1129)
HPKLIDJL_00091 4.03e-263 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HPKLIDJL_00092 1.5e-214 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HPKLIDJL_00093 5.55e-169 epsB - - M - - - biosynthesis protein
HPKLIDJL_00094 1.59e-145 ywqD - - D - - - Capsular exopolysaccharide family
HPKLIDJL_00095 3.4e-179 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HPKLIDJL_00096 3.34e-166 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
HPKLIDJL_00097 1.15e-118 tuaA - - M - - - Bacterial sugar transferase
HPKLIDJL_00098 1.66e-70 - - - M - - - Glycosyltransferase, group 2 family protein
HPKLIDJL_00099 8.96e-138 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HPKLIDJL_00100 1.02e-174 - - - L - - - Transposase and inactivated derivatives, IS30 family
HPKLIDJL_00101 1.73e-61 - - - M - - - Glycosyltransferase like family 2
HPKLIDJL_00102 3.46e-63 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyltransferase
HPKLIDJL_00105 2.12e-49 murJ - - S ko:K03980 - ko00000,ko01011,ko02000 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HPKLIDJL_00107 6.8e-291 - - - L - - - MULE transposase domain
HPKLIDJL_00109 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HPKLIDJL_00112 1.59e-113 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HPKLIDJL_00113 1.8e-217 - - - L ko:K07497 - ko00000 Integrase core domain
HPKLIDJL_00114 1.01e-61 - - - L ko:K07483 - ko00000 Transposase
HPKLIDJL_00115 9.08e-98 - - - L - - - Transposase and inactivated derivatives, IS30 family
HPKLIDJL_00116 1.59e-288 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HPKLIDJL_00118 3.37e-291 - - - L - - - MULE transposase domain
HPKLIDJL_00119 3.16e-193 - - - M - - - Stealth protein CR2, conserved region 2
HPKLIDJL_00120 1.41e-244 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
HPKLIDJL_00121 7.33e-151 - - - L ko:K07497 - ko00000 Integrase core domain
HPKLIDJL_00122 7.8e-41 - - - L ko:K07483 - ko00000 Transposase
HPKLIDJL_00123 1e-177 - - - L ko:K07497 - ko00000 Transposase and inactivated derivatives
HPKLIDJL_00124 1.28e-313 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HPKLIDJL_00125 6.8e-291 - - - L - - - MULE transposase domain
HPKLIDJL_00126 3.07e-68 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
HPKLIDJL_00127 6.77e-290 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HPKLIDJL_00128 7.5e-09 - - - S ko:K09705 - ko00000 Cupin superfamily (DUF985)
HPKLIDJL_00129 2.49e-157 vanR - - K - - - response regulator
HPKLIDJL_00130 1.53e-267 hpk31 - - T - - - Histidine kinase
HPKLIDJL_00131 2.54e-264 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HPKLIDJL_00132 5.91e-178 - - - E - - - AzlC protein
HPKLIDJL_00133 3.16e-78 - - - S - - - branched-chain amino acid
HPKLIDJL_00134 4.12e-213 - - - L - - - PFAM Integrase catalytic region
HPKLIDJL_00135 2.2e-293 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HPKLIDJL_00136 1.51e-05 - - - K - - - Transcriptional regulator C-terminal region
HPKLIDJL_00137 4.03e-223 ydbI - - K - - - AI-2E family transporter
HPKLIDJL_00138 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HPKLIDJL_00139 1.17e-105 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HPKLIDJL_00140 8.32e-276 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HPKLIDJL_00141 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HPKLIDJL_00142 2.3e-220 hrpQ 4.6.1.1 - T ko:K01768,ko:K03220,ko:K10914 ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111 ko00000,ko00001,ko00002,ko01000,ko02044,ko03000 histone H2A K63-linked ubiquitination
HPKLIDJL_00143 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HPKLIDJL_00144 6.13e-174 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HPKLIDJL_00145 1.36e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HPKLIDJL_00146 1.98e-163 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HPKLIDJL_00147 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HPKLIDJL_00148 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HPKLIDJL_00149 2.78e-250 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HPKLIDJL_00150 1.87e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HPKLIDJL_00151 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HPKLIDJL_00152 1.66e-308 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HPKLIDJL_00153 1.15e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPKLIDJL_00154 4.25e-77 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_00155 4.92e-305 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_00156 6.98e-286 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HPKLIDJL_00157 6.78e-225 - - - - - - - -
HPKLIDJL_00158 3.73e-68 - - - S - - - Cupredoxin-like domain
HPKLIDJL_00159 1.55e-66 - - - S - - - Cupredoxin-like domain
HPKLIDJL_00160 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HPKLIDJL_00161 1.2e-34 - - - EGP - - - Major Facilitator
HPKLIDJL_00162 6.87e-117 yejD 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 nucleoside 2-deoxyribosyltransferase
HPKLIDJL_00163 8.34e-101 - - - - - - - -
HPKLIDJL_00166 7.87e-37 - - - S - - - Domain of unknown function (DUF4767)
HPKLIDJL_00167 1.14e-58 yodA - - S - - - Tautomerase enzyme
HPKLIDJL_00168 1.01e-09 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
HPKLIDJL_00170 1.06e-154 pnb - - C - - - nitroreductase
HPKLIDJL_00171 6.25e-103 - 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha/beta hydrolase family
HPKLIDJL_00172 1.27e-101 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HPKLIDJL_00173 1.88e-46 - - - C - - - Aldo keto reductase
HPKLIDJL_00174 3.48e-35 - - - C - - - Aldo keto reductase
HPKLIDJL_00175 4.15e-05 - - - S - - - CsbD-like
HPKLIDJL_00178 5.8e-116 - - - P - - - Cadmium resistance transporter
HPKLIDJL_00179 2.44e-104 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_00180 2e-304 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_00181 1.22e-70 - 4.1.1.44 - O ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HPKLIDJL_00182 1.75e-123 - - - - - - - -
HPKLIDJL_00183 0.0 - - - M - - - Iron Transport-associated domain
HPKLIDJL_00184 3.76e-129 - - - M ko:K14193 ko05150,map05150 ko00000,ko00001 Iron Transport-associated domain
HPKLIDJL_00185 4.62e-195 isdE - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HPKLIDJL_00186 2.57e-200 isdF - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HPKLIDJL_00187 3.13e-181 - 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HPKLIDJL_00188 4.54e-301 proP - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Sugar (and other) transporter
HPKLIDJL_00189 2.75e-25 - - - L - - - Transposase and inactivated derivatives IS30 family
HPKLIDJL_00190 6.43e-165 - - - L - - - MULE transposase domain
HPKLIDJL_00191 1.9e-59 - - - L - - - MULE transposase domain
HPKLIDJL_00193 2.01e-195 gbuA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
HPKLIDJL_00194 3.37e-129 gbuB - - E ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HPKLIDJL_00195 1.03e-129 gbuC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HPKLIDJL_00196 8.84e-58 - - - L - - - Transposase DDE domain group 1
HPKLIDJL_00198 6.83e-81 - - - - - - - -
HPKLIDJL_00199 2e-203 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HPKLIDJL_00200 8.34e-101 - - - - - - - -
HPKLIDJL_00201 3.99e-232 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPKLIDJL_00202 2.59e-45 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-V
HPKLIDJL_00203 4.49e-126 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-V
HPKLIDJL_00204 1.04e-53 - - - C - - - Protein of unknown function (DUF1116)
HPKLIDJL_00206 0.000675 - - - S - - - Protein of unknown function (DUF2877)
HPKLIDJL_00207 1.76e-156 cpkA 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Amino acid kinase family
HPKLIDJL_00208 7.41e-227 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
HPKLIDJL_00209 2.24e-159 - - - C - - - nitroreductase
HPKLIDJL_00210 1.98e-176 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HPKLIDJL_00211 1.06e-70 - - - S - - - Mazg nucleotide pyrophosphohydrolase
HPKLIDJL_00212 3.19e-105 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_00213 2.34e-303 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_00214 8.97e-252 adh1 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HPKLIDJL_00215 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HPKLIDJL_00218 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
HPKLIDJL_00219 4.72e-107 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_00220 4.92e-305 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_00221 8.27e-80 - - - K - - - Transcriptional regulator
HPKLIDJL_00223 3.54e-180 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
HPKLIDJL_00225 4.92e-305 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_00226 3.69e-196 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HPKLIDJL_00227 1.05e-257 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HPKLIDJL_00228 0.0 - - - L - - - DNA helicase
HPKLIDJL_00229 7.95e-222 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HPKLIDJL_00230 5.79e-288 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
HPKLIDJL_00231 7.53e-239 - - - - - - - -
HPKLIDJL_00232 2.31e-165 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
HPKLIDJL_00233 9.67e-272 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
HPKLIDJL_00234 9.96e-209 yunF - - F - - - Protein of unknown function DUF72
HPKLIDJL_00235 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HPKLIDJL_00236 3.29e-189 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
HPKLIDJL_00237 3.77e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HPKLIDJL_00238 1.46e-204 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HPKLIDJL_00239 1.16e-204 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HPKLIDJL_00240 4.04e-212 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HPKLIDJL_00241 1.15e-122 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HPKLIDJL_00242 2.81e-166 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
HPKLIDJL_00243 2.13e-193 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HPKLIDJL_00244 9.91e-302 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HPKLIDJL_00245 7.69e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPKLIDJL_00246 1.89e-78 - - - - - - - -
HPKLIDJL_00247 3.37e-183 yidA - - S - - - hydrolase
HPKLIDJL_00248 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
HPKLIDJL_00249 2.49e-95 ywiB - - S - - - Domain of unknown function (DUF1934)
HPKLIDJL_00250 4.35e-89 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HPKLIDJL_00251 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HPKLIDJL_00252 4.36e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HPKLIDJL_00253 3.85e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HPKLIDJL_00254 1.44e-63 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
HPKLIDJL_00255 1.36e-97 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
HPKLIDJL_00256 3.88e-106 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_00257 4.92e-305 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_00258 5.38e-158 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
HPKLIDJL_00259 7.41e-61 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HPKLIDJL_00260 1.66e-119 lemA - - S ko:K03744 - ko00000 LemA family
HPKLIDJL_00261 1.82e-200 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HPKLIDJL_00262 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HPKLIDJL_00263 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HPKLIDJL_00264 1.18e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HPKLIDJL_00265 1.47e-266 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HPKLIDJL_00266 5.83e-74 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HPKLIDJL_00267 4.51e-148 - - - S - - - (CBS) domain
HPKLIDJL_00268 4.62e-131 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HPKLIDJL_00269 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HPKLIDJL_00270 2.47e-53 yabO - - J - - - S4 domain protein
HPKLIDJL_00271 5.88e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HPKLIDJL_00272 1.65e-113 yabR - - J ko:K07571 - ko00000 RNA binding
HPKLIDJL_00273 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HPKLIDJL_00274 5.21e-126 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HPKLIDJL_00275 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPKLIDJL_00276 4.73e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HPKLIDJL_00277 1.53e-241 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPKLIDJL_00278 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HPKLIDJL_00281 8.34e-101 - - - - - - - -
HPKLIDJL_00284 1.23e-311 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HPKLIDJL_00285 5.36e-67 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HPKLIDJL_00286 3.37e-291 - - - L - - - MULE transposase domain
HPKLIDJL_00287 0.0 - 2.4.1.5 GH13 G ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
HPKLIDJL_00288 3.13e-163 - - - L - - - PFAM transposase, IS4 family protein
HPKLIDJL_00289 3.8e-20 - - - - - - - -
HPKLIDJL_00290 4.76e-290 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HPKLIDJL_00291 1.45e-166 - - - L - - - PFAM transposase, IS4 family protein
HPKLIDJL_00292 8.3e-166 - - - L - - - PFAM transposase, IS4 family protein
HPKLIDJL_00293 3.06e-178 - - - L - - - PFAM Integrase catalytic region
HPKLIDJL_00294 1.35e-164 - - - L - - - PFAM transposase, IS4 family protein
HPKLIDJL_00295 6.81e-159 - - - - - - - -
HPKLIDJL_00296 2.56e-89 - - - L - - - MULE transposase domain
HPKLIDJL_00297 4.26e-210 - - - D - - - nuclear chromosome segregation
HPKLIDJL_00298 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HPKLIDJL_00299 1.08e-208 - - - S - - - Calcineurin-like phosphoesterase
HPKLIDJL_00302 1.39e-150 - - - - - - - -
HPKLIDJL_00303 1.56e-170 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HPKLIDJL_00304 8.7e-166 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HPKLIDJL_00305 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HPKLIDJL_00306 2.71e-195 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HPKLIDJL_00307 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
HPKLIDJL_00308 1.71e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HPKLIDJL_00310 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HPKLIDJL_00311 7.85e-242 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
HPKLIDJL_00312 8.77e-213 - - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
HPKLIDJL_00313 3.17e-164 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPKLIDJL_00314 3.23e-215 - - - I - - - alpha/beta hydrolase fold
HPKLIDJL_00315 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HPKLIDJL_00316 4.03e-143 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HPKLIDJL_00317 1.71e-149 - 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HPKLIDJL_00318 1.47e-105 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_00319 2e-304 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_00320 4.65e-72 HA62_12640 - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
HPKLIDJL_00321 1.62e-123 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
HPKLIDJL_00322 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HPKLIDJL_00323 9.54e-265 yacL - - S - - - domain protein
HPKLIDJL_00324 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HPKLIDJL_00325 1.64e-67 ywlG - - S - - - Belongs to the UPF0340 family
HPKLIDJL_00326 2.41e-47 ywlG - - S - - - Belongs to the UPF0340 family
HPKLIDJL_00327 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HPKLIDJL_00328 1.25e-93 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HPKLIDJL_00329 7.11e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPKLIDJL_00330 5.57e-135 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
HPKLIDJL_00331 7.09e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HPKLIDJL_00332 2.48e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HPKLIDJL_00333 8.34e-127 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HPKLIDJL_00334 3.34e-68 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HPKLIDJL_00335 1.68e-157 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HPKLIDJL_00336 5.22e-311 steT - - E ko:K03294 - ko00000 amino acid
HPKLIDJL_00337 3.88e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HPKLIDJL_00338 8.24e-71 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HPKLIDJL_00339 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
HPKLIDJL_00340 4.17e-237 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
HPKLIDJL_00341 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HPKLIDJL_00342 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HPKLIDJL_00343 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HPKLIDJL_00344 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HPKLIDJL_00345 1.48e-248 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPKLIDJL_00346 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPKLIDJL_00347 6.56e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
HPKLIDJL_00348 3.69e-113 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HPKLIDJL_00350 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPKLIDJL_00351 3.97e-60 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HPKLIDJL_00352 6.48e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HPKLIDJL_00353 2.06e-28 - - - S - - - Protein of unknown function (DUF2508)
HPKLIDJL_00354 6.91e-149 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HPKLIDJL_00355 7.84e-71 yaaQ - - S - - - Cyclic-di-AMP receptor
HPKLIDJL_00356 6.77e-247 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HPKLIDJL_00357 2.47e-74 yabA - - L - - - Involved in initiation control of chromosome replication
HPKLIDJL_00358 4.02e-202 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HPKLIDJL_00359 1.64e-188 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HPKLIDJL_00360 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HPKLIDJL_00361 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HPKLIDJL_00362 1.67e-221 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HPKLIDJL_00363 8.55e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HPKLIDJL_00364 6.98e-206 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
HPKLIDJL_00365 2.08e-239 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HPKLIDJL_00366 4.08e-218 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
HPKLIDJL_00367 5.72e-304 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
HPKLIDJL_00368 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HPKLIDJL_00369 3.8e-31 - - - L ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Helix-turn-helix domain
HPKLIDJL_00370 3.1e-215 - - - L - - - PFAM Integrase catalytic region
HPKLIDJL_00371 8.37e-282 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HPKLIDJL_00372 4.61e-274 arcT - - E - - - Aminotransferase
HPKLIDJL_00373 2.78e-167 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
HPKLIDJL_00374 6.22e-140 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
HPKLIDJL_00375 3.65e-250 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HPKLIDJL_00377 3.83e-100 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HPKLIDJL_00378 1.32e-97 - - - K - - - Transcriptional regulator, MarR family
HPKLIDJL_00379 3.09e-218 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HPKLIDJL_00380 4.18e-46 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HPKLIDJL_00381 9.23e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
HPKLIDJL_00382 1.27e-163 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HPKLIDJL_00383 1.32e-291 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HPKLIDJL_00384 3.46e-94 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HPKLIDJL_00385 1.13e-97 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HPKLIDJL_00386 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
HPKLIDJL_00387 2.25e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HPKLIDJL_00388 4.46e-180 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
HPKLIDJL_00389 1.55e-174 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HPKLIDJL_00390 3.37e-117 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HPKLIDJL_00391 1.04e-224 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HPKLIDJL_00392 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
HPKLIDJL_00393 8.05e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HPKLIDJL_00394 1.15e-57 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HPKLIDJL_00395 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HPKLIDJL_00396 0.0 ydaO - - E - - - amino acid
HPKLIDJL_00397 4.12e-50 - - - - - - - -
HPKLIDJL_00398 4e-147 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
HPKLIDJL_00399 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
HPKLIDJL_00400 6.17e-166 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
HPKLIDJL_00401 4.64e-124 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HPKLIDJL_00402 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HPKLIDJL_00403 5.89e-257 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HPKLIDJL_00404 1.97e-70 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
HPKLIDJL_00405 4.15e-69 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
HPKLIDJL_00406 1.38e-226 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HPKLIDJL_00407 9.22e-210 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HPKLIDJL_00408 9.09e-236 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HPKLIDJL_00409 7.64e-220 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HPKLIDJL_00410 8.73e-188 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
HPKLIDJL_00411 1.03e-287 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HPKLIDJL_00412 1.25e-240 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HPKLIDJL_00413 5.48e-102 yphH - - S - - - Cupin domain
HPKLIDJL_00414 8.22e-167 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HPKLIDJL_00415 3.44e-200 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
HPKLIDJL_00416 1.72e-214 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HPKLIDJL_00417 7.11e-37 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HPKLIDJL_00418 8.67e-37 - - - L - - - Transposase and inactivated derivatives IS30 family
HPKLIDJL_00419 2.39e-254 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HPKLIDJL_00420 1.59e-217 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HPKLIDJL_00421 4.18e-176 - - - S - - - haloacid dehalogenase-like hydrolase
HPKLIDJL_00422 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HPKLIDJL_00423 1.02e-144 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
HPKLIDJL_00425 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HPKLIDJL_00426 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HPKLIDJL_00427 5.07e-261 - - - - - - - -
HPKLIDJL_00428 9.14e-205 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HPKLIDJL_00429 4.71e-239 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HPKLIDJL_00430 2.34e-214 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HPKLIDJL_00431 1.4e-153 - 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HPKLIDJL_00432 2.96e-132 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HPKLIDJL_00436 3.7e-299 - - - L ko:K07485 - ko00000 Transposase
HPKLIDJL_00437 1.53e-19 - - - - - - - -
HPKLIDJL_00438 2.46e-102 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
HPKLIDJL_00439 5.72e-196 - - - L - - - MULE transposase domain
HPKLIDJL_00440 5.38e-272 - - - L - - - Transposase and inactivated derivatives, IS30 family
HPKLIDJL_00441 2.16e-26 - - - L - - - Plasmid pRiA4b ORF-3-like protein
HPKLIDJL_00442 3.82e-23 - - - - - - - -
HPKLIDJL_00443 1.31e-244 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HPKLIDJL_00444 4.22e-287 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HPKLIDJL_00445 2.92e-184 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HPKLIDJL_00446 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPKLIDJL_00447 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
HPKLIDJL_00448 0.0 eriC - - P ko:K03281 - ko00000 chloride
HPKLIDJL_00449 6.82e-46 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HPKLIDJL_00450 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HPKLIDJL_00451 4.66e-110 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HPKLIDJL_00452 1.66e-139 - - - - - - - -
HPKLIDJL_00453 4.52e-175 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HPKLIDJL_00454 9.74e-229 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
HPKLIDJL_00455 4.21e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
HPKLIDJL_00456 1.3e-116 - - - K - - - Acetyltransferase (GNAT) domain
HPKLIDJL_00457 6.64e-132 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HPKLIDJL_00458 2.34e-212 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HPKLIDJL_00459 1.61e-192 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HPKLIDJL_00460 1.69e-151 ybbR - - S - - - YbbR-like protein
HPKLIDJL_00461 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HPKLIDJL_00462 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HPKLIDJL_00463 2.55e-68 - - - - - - - -
HPKLIDJL_00464 2.9e-263 oatA - - I - - - Acyltransferase
HPKLIDJL_00465 8.67e-193 XK27_02985 - - S - - - Sucrose-6F-phosphate phosphohydrolase
HPKLIDJL_00466 7.87e-112 lytE - - M - - - Lysin motif
HPKLIDJL_00467 6.96e-222 - - - S - - - Conserved hypothetical protein 698
HPKLIDJL_00468 4.95e-215 - - - K - - - LysR substrate binding domain
HPKLIDJL_00469 9.48e-165 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HPKLIDJL_00470 2.31e-193 yitS - - S - - - EDD domain protein, DegV family
HPKLIDJL_00471 8.77e-117 - - - K - - - Domain of unknown function (DUF1836)
HPKLIDJL_00472 1.5e-231 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
HPKLIDJL_00473 4.48e-231 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HPKLIDJL_00474 2.38e-164 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
HPKLIDJL_00475 1.37e-219 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
HPKLIDJL_00476 1.8e-76 manO - - S - - - Domain of unknown function (DUF956)
HPKLIDJL_00478 1.39e-170 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
HPKLIDJL_00479 0.0 yclK - - T - - - Histidine kinase
HPKLIDJL_00480 1.44e-195 - - - U ko:K05340 - ko00000,ko02000 sugar transport
HPKLIDJL_00481 3.8e-31 - - - L ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Helix-turn-helix domain
HPKLIDJL_00482 7.62e-216 - - - L - - - PFAM Integrase catalytic region
HPKLIDJL_00483 9.36e-101 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HPKLIDJL_00484 1.88e-135 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
HPKLIDJL_00485 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
HPKLIDJL_00486 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HPKLIDJL_00488 5.74e-93 - - - K - - - GNAT family
HPKLIDJL_00489 5.19e-158 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
HPKLIDJL_00490 9.18e-206 yvgN - - S - - - Aldo keto reductase
HPKLIDJL_00491 5.46e-186 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HPKLIDJL_00492 6.37e-169 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
HPKLIDJL_00494 2.67e-75 - - - - - - - -
HPKLIDJL_00496 3.24e-10 - - - - - - - -
HPKLIDJL_00497 1.02e-102 - - - K - - - Winged helix-turn-helix DNA-binding
HPKLIDJL_00498 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HPKLIDJL_00499 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
HPKLIDJL_00500 4.58e-246 ampC - - V - - - Beta-lactamase
HPKLIDJL_00501 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPKLIDJL_00502 2.31e-63 - - - - - - - -
HPKLIDJL_00503 7.49e-181 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
HPKLIDJL_00504 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
HPKLIDJL_00505 1.78e-139 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HPKLIDJL_00506 5.36e-208 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HPKLIDJL_00507 1.11e-202 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HPKLIDJL_00508 8.28e-251 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HPKLIDJL_00509 2.12e-292 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HPKLIDJL_00510 3.86e-149 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HPKLIDJL_00511 2e-252 yibE - - S - - - overlaps another CDS with the same product name
HPKLIDJL_00512 2.24e-164 yibF - - S - - - overlaps another CDS with the same product name
HPKLIDJL_00513 1.1e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
HPKLIDJL_00514 5.66e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HPKLIDJL_00515 2.13e-27 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPKLIDJL_00516 2.37e-81 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HPKLIDJL_00517 4.1e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPKLIDJL_00518 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HPKLIDJL_00519 1.78e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HPKLIDJL_00520 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HPKLIDJL_00521 1.19e-88 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HPKLIDJL_00522 8.07e-40 - - - S - - - Protein of unknown function (DUF1146)
HPKLIDJL_00523 2.4e-278 - - - M - - - EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
HPKLIDJL_00524 5.45e-233 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
HPKLIDJL_00525 7.67e-43 - - - S - - - Protein of unknown function (DUF2969)
HPKLIDJL_00526 5.09e-283 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HPKLIDJL_00528 1.15e-232 - - - S - - - Protein of unknown function (DUF2785)
HPKLIDJL_00529 5.85e-275 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HPKLIDJL_00530 6.8e-316 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HPKLIDJL_00531 1.7e-195 - - - K - - - Helix-turn-helix XRE-family like proteins
HPKLIDJL_00532 6.08e-107 uspA - - T - - - universal stress protein
HPKLIDJL_00534 1.3e-300 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HPKLIDJL_00535 8.04e-111 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
HPKLIDJL_00536 1.52e-98 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
HPKLIDJL_00537 2.3e-173 - - - S - - - Membrane
HPKLIDJL_00538 7.09e-189 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HPKLIDJL_00539 1.25e-15 - - - S - - - YjcQ protein
HPKLIDJL_00541 5.1e-140 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HPKLIDJL_00542 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HPKLIDJL_00543 1.43e-273 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HPKLIDJL_00544 2.03e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HPKLIDJL_00545 1.61e-277 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
HPKLIDJL_00546 3.17e-260 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HPKLIDJL_00547 5.07e-43 - - - M - - - LysM domain
HPKLIDJL_00548 1.61e-52 - - - - - - - -
HPKLIDJL_00549 1.74e-49 - - - S - - - zinc-ribbon domain
HPKLIDJL_00553 3.11e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HPKLIDJL_00554 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HPKLIDJL_00555 4e-314 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HPKLIDJL_00556 5.3e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
HPKLIDJL_00557 1.56e-231 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
HPKLIDJL_00558 1.95e-187 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HPKLIDJL_00559 2.59e-119 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
HPKLIDJL_00560 3.81e-142 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HPKLIDJL_00561 4.86e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HPKLIDJL_00562 1.65e-205 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HPKLIDJL_00563 1.34e-297 ymfF - - S - - - Peptidase M16 inactive domain protein
HPKLIDJL_00564 0.0 ymfH - - S - - - Peptidase M16
HPKLIDJL_00565 1.64e-151 - - - S - - - Helix-turn-helix domain
HPKLIDJL_00566 1.79e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HPKLIDJL_00567 1.62e-293 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HPKLIDJL_00568 7.88e-245 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HPKLIDJL_00569 2.27e-305 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HPKLIDJL_00570 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HPKLIDJL_00571 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HPKLIDJL_00572 5.09e-135 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HPKLIDJL_00573 3.61e-243 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HPKLIDJL_00574 8.89e-226 - 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 queuine tRNA-ribosyltransferase activity
HPKLIDJL_00575 1.5e-66 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HPKLIDJL_00576 2.3e-229 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
HPKLIDJL_00577 1.7e-300 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HPKLIDJL_00578 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HPKLIDJL_00579 1.06e-57 yrzL - - S - - - Belongs to the UPF0297 family
HPKLIDJL_00580 4.97e-97 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HPKLIDJL_00581 7.75e-53 yrzB - - S - - - Belongs to the UPF0473 family
HPKLIDJL_00582 3.2e-211 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPKLIDJL_00583 2.23e-119 cvpA - - S - - - Colicin V production protein
HPKLIDJL_00584 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HPKLIDJL_00585 1.37e-70 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HPKLIDJL_00586 7.25e-284 - - - P - - - Chloride transporter, ClC family
HPKLIDJL_00587 1.44e-122 yslB - - S - - - Protein of unknown function (DUF2507)
HPKLIDJL_00588 6.11e-188 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HPKLIDJL_00589 2.65e-140 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HPKLIDJL_00590 3.33e-123 - - - S ko:K07095 - ko00000 Phosphoesterase
HPKLIDJL_00591 1.75e-193 - - - S - - - haloacid dehalogenase-like hydrolase
HPKLIDJL_00592 4.32e-200 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
HPKLIDJL_00593 5.99e-67 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HPKLIDJL_00594 4.62e-92 - - - - - - - -
HPKLIDJL_00595 1.08e-272 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HPKLIDJL_00596 5.94e-238 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HPKLIDJL_00597 6.95e-182 - - - - - - - -
HPKLIDJL_00598 5.01e-172 yebC - - K - - - Transcriptional regulatory protein
HPKLIDJL_00599 5.17e-120 - - - M - - - PFAM NLP P60 protein
HPKLIDJL_00600 1.22e-185 ykcB - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
HPKLIDJL_00601 6.2e-226 ykcB - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
HPKLIDJL_00602 1.33e-228 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
HPKLIDJL_00603 2.13e-212 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
HPKLIDJL_00604 8.88e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
HPKLIDJL_00609 8.77e-203 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HPKLIDJL_00610 3.74e-284 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPKLIDJL_00611 2.73e-147 - - - S - - - Calcineurin-like phosphoesterase
HPKLIDJL_00612 3.84e-126 yutD - - S - - - Protein of unknown function (DUF1027)
HPKLIDJL_00613 3.39e-181 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HPKLIDJL_00614 2.65e-21 - - - S - - - Protein of unknown function (DUF1461)
HPKLIDJL_00615 8.3e-142 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
HPKLIDJL_00616 8.34e-101 - - - - - - - -
HPKLIDJL_00637 1.12e-90 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HPKLIDJL_00638 8.81e-152 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HPKLIDJL_00639 4.85e-262 coiA - - S ko:K06198 - ko00000 Competence protein
HPKLIDJL_00640 2.07e-147 yjbH - - Q - - - Thioredoxin
HPKLIDJL_00641 5.24e-159 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HPKLIDJL_00642 9.49e-197 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HPKLIDJL_00643 5.39e-221 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HPKLIDJL_00644 1.61e-252 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HPKLIDJL_00645 3.9e-208 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
HPKLIDJL_00646 2.01e-123 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HPKLIDJL_00647 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HPKLIDJL_00648 4.5e-12 - - - S - - - Protein of unknown function (DUF4044)
HPKLIDJL_00649 6.91e-76 - - - - - - - -
HPKLIDJL_00650 8.95e-103 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HPKLIDJL_00651 5.37e-221 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HPKLIDJL_00652 3.03e-30 ftsL - - D - - - Cell division protein FtsL
HPKLIDJL_00653 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HPKLIDJL_00654 1.28e-226 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HPKLIDJL_00655 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HPKLIDJL_00656 5.66e-257 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HPKLIDJL_00657 5.43e-193 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HPKLIDJL_00658 4.88e-300 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HPKLIDJL_00659 1.49e-292 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HPKLIDJL_00660 1.01e-99 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HPKLIDJL_00661 7.27e-56 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
HPKLIDJL_00662 1.75e-186 ylmH - - S - - - S4 domain protein
HPKLIDJL_00663 6.19e-143 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
HPKLIDJL_00665 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HPKLIDJL_00666 9.99e-44 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HPKLIDJL_00667 1.28e-126 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HPKLIDJL_00669 1.33e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HPKLIDJL_00670 7.86e-77 XK27_04120 - - S - - - Putative amino acid metabolism
HPKLIDJL_00671 3.43e-283 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HPKLIDJL_00672 2.77e-244 - - - S - - - amidohydrolase
HPKLIDJL_00673 1.21e-115 - - - S - - - amidohydrolase
HPKLIDJL_00674 1.08e-218 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HPKLIDJL_00675 1.11e-156 pgm6 - - G - - - phosphoglycerate mutase
HPKLIDJL_00676 9.37e-159 - - - S - - - repeat protein
HPKLIDJL_00677 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HPKLIDJL_00678 3.81e-228 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPKLIDJL_00679 2.39e-98 - - - P - - - ArsC family
HPKLIDJL_00680 2.95e-239 - - - I - - - Diacylglycerol kinase catalytic
HPKLIDJL_00681 8.83e-43 ykzG - - S - - - Belongs to the UPF0356 family
HPKLIDJL_00682 6.12e-98 - - - - - - - -
HPKLIDJL_00683 8.59e-133 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HPKLIDJL_00684 1.55e-65 yktA - - S - - - Belongs to the UPF0223 family
HPKLIDJL_00685 1.96e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
HPKLIDJL_00686 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HPKLIDJL_00687 1.02e-277 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HPKLIDJL_00688 1.31e-63 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
HPKLIDJL_00689 1.27e-128 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
HPKLIDJL_00690 2.06e-114 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HPKLIDJL_00691 2.29e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HPKLIDJL_00692 1.47e-127 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
HPKLIDJL_00693 8.66e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HPKLIDJL_00694 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HPKLIDJL_00695 1.63e-236 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HPKLIDJL_00696 2.9e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HPKLIDJL_00697 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HPKLIDJL_00698 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HPKLIDJL_00699 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPKLIDJL_00700 1.15e-208 - - - S - - - Tetratricopeptide repeat
HPKLIDJL_00701 9.97e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HPKLIDJL_00702 1.15e-299 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HPKLIDJL_00703 2.06e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HPKLIDJL_00704 5.34e-140 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HPKLIDJL_00705 1.84e-68 - - - S - - - mazG nucleotide pyrophosphohydrolase
HPKLIDJL_00707 3.97e-174 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HPKLIDJL_00708 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HPKLIDJL_00709 9.56e-317 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HPKLIDJL_00710 8.64e-225 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HPKLIDJL_00711 1.3e-199 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HPKLIDJL_00712 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HPKLIDJL_00713 2.41e-123 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HPKLIDJL_00714 1.64e-81 - - - S - - - Domain of unknown function (DUF4440)
HPKLIDJL_00715 7.82e-239 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPKLIDJL_00716 1.51e-193 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
HPKLIDJL_00717 1.03e-105 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_00718 2e-304 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_00719 1.34e-126 ydeQ - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
HPKLIDJL_00720 2.05e-59 - - - S - - - Protein conserved in bacteria
HPKLIDJL_00721 3.03e-74 - - - S - - - Antibiotic biosynthesis monooxygenase
HPKLIDJL_00722 1.29e-66 - - - S - - - Sugar efflux transporter for intercellular exchange
HPKLIDJL_00723 2.47e-13 - - - K - - - transcriptional
HPKLIDJL_00724 2.89e-252 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
HPKLIDJL_00725 1.48e-219 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HPKLIDJL_00726 1.21e-118 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
HPKLIDJL_00727 1.41e-132 - - - L - - - Transposase and inactivated derivatives, IS30 family
HPKLIDJL_00728 9.29e-86 - - - P - - - Voltage gated chloride channel
HPKLIDJL_00729 8.28e-292 - - - L - - - MULE transposase domain
HPKLIDJL_00730 1.73e-218 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HPKLIDJL_00731 1.35e-164 - - - L - - - PFAM transposase, IS4 family protein
HPKLIDJL_00734 5.07e-241 - - - EGP - - - Major Facilitator
HPKLIDJL_00736 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Aluminium induced protein
HPKLIDJL_00738 3.94e-14 - - - S - - - CHY zinc finger
HPKLIDJL_00741 2.09e-22 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
HPKLIDJL_00743 4.88e-236 fruR3 - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
HPKLIDJL_00744 9.97e-103 - - - F - - - Nucleoside 2-deoxyribosyltransferase
HPKLIDJL_00745 4.72e-128 - - - - - - - -
HPKLIDJL_00747 2.54e-248 int3 - - L - - - Belongs to the 'phage' integrase family
HPKLIDJL_00748 1.95e-97 - - - - - - - -
HPKLIDJL_00750 6.12e-10 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_00751 1.1e-314 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HPKLIDJL_00752 3.8e-222 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HPKLIDJL_00753 0.0 ybeC - - E - - - amino acid
HPKLIDJL_00754 3.8e-222 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HPKLIDJL_00755 9.29e-138 - - - K - - - Bacterial regulatory proteins, tetR family
HPKLIDJL_00756 2.2e-66 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HPKLIDJL_00757 1.94e-86 - - - - - - - -
HPKLIDJL_00758 1.58e-70 - - - - - - - -
HPKLIDJL_00759 1.7e-280 - - - S - - - Domain of unknown function (DUF389)
HPKLIDJL_00760 2e-300 yagE - - E - - - Amino acid permease
HPKLIDJL_00761 1.24e-165 tnp1216 - - L ko:K07498 - ko00000 DDE domain
HPKLIDJL_00762 0.0 - - - G - - - Major Facilitator Superfamily
HPKLIDJL_00763 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HPKLIDJL_00765 1.97e-211 yeeA - - V - - - Type II restriction enzyme, methylase subunits
HPKLIDJL_00766 2.48e-62 - - - L ko:K07483 - ko00000 Transposase
HPKLIDJL_00767 4.42e-218 - - - L ko:K07497 - ko00000 Integrase core domain
HPKLIDJL_00768 2.37e-167 yeeA - - V - - - Type II restriction enzyme, methylase subunits
HPKLIDJL_00769 1.72e-08 - - - - - - - -
HPKLIDJL_00770 1.15e-20 - - - L - - - MULE transposase domain
HPKLIDJL_00771 2.45e-56 - - - S - - - SEFIR domain
HPKLIDJL_00772 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HPKLIDJL_00775 3.61e-132 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HPKLIDJL_00776 5.15e-247 - - - L - - - Transposase and inactivated derivatives, IS30 family
HPKLIDJL_00777 2.43e-98 - - - S - - - Short repeat of unknown function (DUF308)
HPKLIDJL_00780 1.63e-82 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HPKLIDJL_00781 1.26e-140 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HPKLIDJL_00782 1.74e-34 yitW - - S - - - DNA methyltransferase
HPKLIDJL_00783 2.07e-46 - - - M - - - domain protein
HPKLIDJL_00785 4.96e-68 - - - M - - - LPXTG-motif cell wall anchor domain protein
HPKLIDJL_00786 7.68e-28 - - - M - - - LPXTG-motif cell wall anchor domain protein
HPKLIDJL_00787 1.85e-108 lutC - - S ko:K00782 - ko00000 LUD domain
HPKLIDJL_00788 6.16e-307 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
HPKLIDJL_00789 7.91e-155 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
HPKLIDJL_00790 4.28e-274 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
HPKLIDJL_00791 1.25e-148 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HPKLIDJL_00792 5.66e-49 ynzC - - S - - - UPF0291 protein
HPKLIDJL_00793 1.05e-36 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
HPKLIDJL_00794 3.06e-150 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
HPKLIDJL_00795 2.3e-174 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
HPKLIDJL_00796 1.55e-61 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
HPKLIDJL_00797 6.34e-181 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HPKLIDJL_00798 3.4e-197 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HPKLIDJL_00799 6.84e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HPKLIDJL_00800 5.35e-121 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HPKLIDJL_00801 2.7e-185 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HPKLIDJL_00802 1.17e-173 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HPKLIDJL_00803 8.02e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HPKLIDJL_00804 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HPKLIDJL_00805 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPKLIDJL_00806 3.26e-275 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
HPKLIDJL_00807 2.39e-175 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HPKLIDJL_00808 2.8e-255 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HPKLIDJL_00809 2.08e-241 - - - L ko:K07482 - ko00000 Helix-turn-helix domain
HPKLIDJL_00810 5.6e-06 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HPKLIDJL_00811 4.99e-251 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HPKLIDJL_00812 4.36e-264 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HPKLIDJL_00813 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HPKLIDJL_00814 8.99e-109 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HPKLIDJL_00815 6.7e-283 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HPKLIDJL_00816 3.71e-64 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
HPKLIDJL_00817 5.5e-67 ylxQ - - J - - - ribosomal protein
HPKLIDJL_00818 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HPKLIDJL_00819 1.49e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HPKLIDJL_00820 3.76e-213 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HPKLIDJL_00821 2.15e-235 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HPKLIDJL_00822 9e-317 - - - U - - - Belongs to the major facilitator superfamily
HPKLIDJL_00823 1.49e-74 - - - L - - - Helix-turn-helix domain
HPKLIDJL_00824 4.4e-25 - - - L ko:K07497 - ko00000 hmm pf00665
HPKLIDJL_00825 4.19e-152 - - - L ko:K07497 - ko00000 hmm pf00665
HPKLIDJL_00826 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HPKLIDJL_00827 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HPKLIDJL_00828 2.2e-227 - - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
HPKLIDJL_00829 1.37e-196 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
HPKLIDJL_00831 2.17e-288 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
HPKLIDJL_00833 8.28e-292 - - - L - - - MULE transposase domain
HPKLIDJL_00834 7.34e-217 - - - L ko:K07497 - ko00000 Integrase core domain
HPKLIDJL_00835 1.84e-238 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HPKLIDJL_00836 1.39e-31 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
HPKLIDJL_00837 4.95e-123 ybcH - - D ko:K06889 - ko00000 Alpha beta
HPKLIDJL_00838 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
HPKLIDJL_00839 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HPKLIDJL_00840 2.48e-62 - - - L ko:K07483 - ko00000 Transposase
HPKLIDJL_00841 1.8e-217 - - - L ko:K07497 - ko00000 Integrase core domain
HPKLIDJL_00842 3.87e-80 - - - - - - - -
HPKLIDJL_00843 1.21e-244 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HPKLIDJL_00844 5.35e-84 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HPKLIDJL_00845 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HPKLIDJL_00846 9.95e-267 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HPKLIDJL_00847 6.5e-123 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HPKLIDJL_00848 2.15e-11 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HPKLIDJL_00849 1.34e-62 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HPKLIDJL_00850 1.48e-214 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
HPKLIDJL_00851 2.49e-276 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HPKLIDJL_00852 5.28e-139 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HPKLIDJL_00853 2.12e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HPKLIDJL_00854 5.12e-132 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
HPKLIDJL_00855 1.21e-143 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HPKLIDJL_00856 2.29e-165 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HPKLIDJL_00857 3.14e-182 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HPKLIDJL_00858 5.32e-73 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HPKLIDJL_00859 2.63e-69 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
HPKLIDJL_00860 2.58e-254 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HPKLIDJL_00861 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HPKLIDJL_00862 1.35e-164 - - - L - - - PFAM transposase, IS4 family protein
HPKLIDJL_00864 3.72e-145 pgm1 - - G - - - phosphoglycerate mutase
HPKLIDJL_00865 9.45e-07 - - - C - - - aldo keto reductase
HPKLIDJL_00866 2.97e-105 - - - C - - - aldo keto reductase
HPKLIDJL_00867 7.18e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HPKLIDJL_00868 8.79e-284 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPKLIDJL_00869 0.0 - - - K - - - COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HPKLIDJL_00870 7.88e-103 - - - K - - - 2 iron, 2 sulfur cluster binding
HPKLIDJL_00871 1.14e-105 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HPKLIDJL_00872 4.58e-289 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HPKLIDJL_00873 1.25e-136 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
HPKLIDJL_00874 2.81e-258 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HPKLIDJL_00875 2.05e-45 - - - C - - - Flavodoxin
HPKLIDJL_00876 2.71e-198 - - - L ko:K07497 - ko00000 hmm pf00665
HPKLIDJL_00877 1.06e-72 - - - L - - - Helix-turn-helix domain
HPKLIDJL_00878 6.28e-271 - - - L - - - Transposase and inactivated derivatives, IS30 family
HPKLIDJL_00879 5.34e-29 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_00880 1.7e-183 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_00881 1.12e-64 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_00882 3.32e-28 - - - T - - - His Kinase A (phosphoacceptor) domain
HPKLIDJL_00883 1.21e-240 - - - L ko:K07482 - ko00000 Helix-turn-helix domain
HPKLIDJL_00884 7.8e-282 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HPKLIDJL_00886 1.03e-105 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_00887 5.5e-302 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_00888 3.14e-132 cadD - - P - - - Cadmium resistance transporter
HPKLIDJL_00889 1.55e-151 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HPKLIDJL_00890 5.05e-136 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPKLIDJL_00891 5.95e-202 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HPKLIDJL_00892 4.53e-127 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPKLIDJL_00895 2.59e-204 - 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
HPKLIDJL_00896 7.25e-88 - - - K - - - LysR substrate binding domain
HPKLIDJL_00897 1.71e-244 - 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
HPKLIDJL_00898 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 GXGXG motif
HPKLIDJL_00899 1.44e-269 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HPKLIDJL_00900 2.87e-52 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
HPKLIDJL_00901 2.94e-89 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
HPKLIDJL_00902 6.81e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HPKLIDJL_00903 1.76e-146 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HPKLIDJL_00904 1.1e-184 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HPKLIDJL_00905 6.34e-182 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HPKLIDJL_00906 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HPKLIDJL_00907 2.16e-114 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
HPKLIDJL_00908 3.58e-125 - - - L - - - restriction endonuclease
HPKLIDJL_00909 0.0 - - - L - - - Type III restriction enzyme, res subunit
HPKLIDJL_00910 0.0 - - - S - - - Protein of unknown function DUF262
HPKLIDJL_00911 3.28e-196 - - - L - - - MULE transposase domain
HPKLIDJL_00912 1.05e-74 - - - L - - - Helix-turn-helix domain
HPKLIDJL_00913 5.4e-22 - - - L ko:K07497 - ko00000 hmm pf00665
HPKLIDJL_00914 1.7e-151 - - - L ko:K07497 - ko00000 hmm pf00665
HPKLIDJL_00915 5.81e-222 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HPKLIDJL_00917 3.97e-71 - - - - - - - -
HPKLIDJL_00918 3.62e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
HPKLIDJL_00919 1.05e-174 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HPKLIDJL_00920 1.72e-75 - - - - - - - -
HPKLIDJL_00921 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HPKLIDJL_00922 8.94e-100 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HPKLIDJL_00923 1.01e-108 - - - K - - - Transcriptional regulator
HPKLIDJL_00924 6.92e-280 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HPKLIDJL_00925 4.6e-271 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
HPKLIDJL_00927 3.96e-146 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
HPKLIDJL_00928 3.24e-147 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
HPKLIDJL_00929 3.4e-174 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HPKLIDJL_00930 2.14e-196 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HPKLIDJL_00931 1.02e-225 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
HPKLIDJL_00932 1.03e-105 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_00933 2e-304 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_00934 1.05e-16 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
HPKLIDJL_00935 1.85e-201 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
HPKLIDJL_00936 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HPKLIDJL_00937 7.39e-98 - - - L - - - Transposase DDE domain
HPKLIDJL_00938 3.75e-86 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HPKLIDJL_00939 2.94e-211 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
HPKLIDJL_00940 1.3e-55 - - - G - - - Phosphotransferase enzyme family
HPKLIDJL_00941 2.65e-117 - - - G - - - Phosphotransferase enzyme family
HPKLIDJL_00942 2.57e-225 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Ami_3
HPKLIDJL_00943 2.99e-248 - 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HPKLIDJL_00944 1.62e-313 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HPKLIDJL_00945 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HPKLIDJL_00946 1.83e-164 - - - F - - - glutamine amidotransferase
HPKLIDJL_00947 3.81e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HPKLIDJL_00948 7.23e-92 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
HPKLIDJL_00949 3.02e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
HPKLIDJL_00950 2.91e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HPKLIDJL_00951 7.64e-88 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HPKLIDJL_00952 8.91e-218 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HPKLIDJL_00953 1.52e-199 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HPKLIDJL_00954 1.03e-239 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HPKLIDJL_00955 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HPKLIDJL_00956 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HPKLIDJL_00957 1.21e-264 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HPKLIDJL_00958 2.71e-96 is18 - - L - - - COG2801 Transposase and inactivated derivatives
HPKLIDJL_00959 4.76e-290 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HPKLIDJL_00960 1.94e-92 is18 - - L - - - Integrase core domain
HPKLIDJL_00961 1.44e-51 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
HPKLIDJL_00962 3.87e-114 - - - - - - - -
HPKLIDJL_00963 3.56e-31 - - - S - - - Small integral membrane protein (DUF2273)
HPKLIDJL_00964 3.37e-96 asp1 - - S - - - Asp23 family, cell envelope-related function
HPKLIDJL_00965 1.19e-41 - - - S - - - Transglycosylase associated protein
HPKLIDJL_00966 4.74e-23 - - - - - - - -
HPKLIDJL_00967 1.82e-313 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HPKLIDJL_00968 2.02e-215 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPKLIDJL_00969 8.7e-233 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HPKLIDJL_00970 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HPKLIDJL_00971 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HPKLIDJL_00972 5.23e-114 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HPKLIDJL_00973 4.67e-280 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HPKLIDJL_00974 1.09e-223 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HPKLIDJL_00975 5.43e-182 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HPKLIDJL_00976 3.98e-277 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HPKLIDJL_00977 1.28e-253 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HPKLIDJL_00978 3.38e-293 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
HPKLIDJL_00979 1.97e-153 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
HPKLIDJL_00980 8.01e-162 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HPKLIDJL_00981 2e-200 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HPKLIDJL_00982 5.08e-301 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HPKLIDJL_00984 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HPKLIDJL_00985 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HPKLIDJL_00986 6.26e-215 yitL - - S ko:K00243 - ko00000 S1 domain
HPKLIDJL_00987 8.52e-175 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
HPKLIDJL_00988 2.23e-89 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HPKLIDJL_00989 3.39e-182 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HPKLIDJL_00990 3.2e-131 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HPKLIDJL_00991 1.44e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HPKLIDJL_00992 2.03e-112 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HPKLIDJL_00993 1.34e-254 - - - S - - - Helix-turn-helix domain
HPKLIDJL_00994 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HPKLIDJL_00995 4.37e-76 - - - M - - - Lysin motif
HPKLIDJL_00996 2.29e-153 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HPKLIDJL_00997 4.63e-275 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HPKLIDJL_00998 1.29e-313 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HPKLIDJL_00999 2.65e-53 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HPKLIDJL_01000 2.52e-300 XK27_05225 - - S - - - Tetratricopeptide repeat protein
HPKLIDJL_01001 1.29e-211 - - - L - - - Phage integrase, N-terminal SAM-like domain
HPKLIDJL_01002 1.2e-281 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HPKLIDJL_01003 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
HPKLIDJL_01004 5.32e-244 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HPKLIDJL_01005 4.4e-122 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HPKLIDJL_01006 8.06e-141 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
HPKLIDJL_01007 2.23e-196 WQ51_01275 - - S - - - EDD domain protein, DegV family
HPKLIDJL_01008 2.06e-278 - 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase
HPKLIDJL_01009 1.2e-146 cat 2.3.1.79 - S ko:K00661,ko:K18234 - ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
HPKLIDJL_01010 2.46e-217 - - - E - - - lipolytic protein G-D-S-L family
HPKLIDJL_01011 2.85e-135 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
HPKLIDJL_01012 2.1e-49 yozE - - S - - - Belongs to the UPF0346 family
HPKLIDJL_01013 1.85e-214 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HPKLIDJL_01014 5.62e-86 - - - K ko:K03892 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
HPKLIDJL_01015 9.46e-67 - - - S - - - Arsenical resistance operon trans-acting repressor ArsD
HPKLIDJL_01016 8.28e-292 - - - L - - - MULE transposase domain
HPKLIDJL_01017 0.0 arsA 3.6.3.16 - D ko:K01551 - ko00000,ko01000,ko02000 Anion-transporting ATPase
HPKLIDJL_01018 4.48e-295 arsB - - U ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HPKLIDJL_01019 5.45e-68 - - - - - - - -
HPKLIDJL_01020 4.76e-290 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HPKLIDJL_01021 1.35e-164 - - - L - - - PFAM transposase, IS4 family protein
HPKLIDJL_01022 0.0 nox 1.11.1.1 - P ko:K05910 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HPKLIDJL_01023 8.28e-292 - - - L - - - MULE transposase domain
HPKLIDJL_01024 4.58e-82 - - - K - - - Transcriptional regulator
HPKLIDJL_01025 2.21e-131 cadD - - P - - - Cadmium resistance transporter
HPKLIDJL_01026 2.21e-160 - - - L - - - PFAM transposase, IS4 family protein
HPKLIDJL_01027 7.61e-18 - - - K - - - Cro/C1-type HTH DNA-binding domain
HPKLIDJL_01028 9.09e-44 - - - K ko:K07467 - ko00000 Replication initiation factor
HPKLIDJL_01029 1.35e-164 - - - L - - - PFAM transposase, IS4 family protein
HPKLIDJL_01030 1.09e-35 - - - K ko:K07467 - ko00000 Replication initiation factor
HPKLIDJL_01031 1.02e-30 - - - - - - - -
HPKLIDJL_01032 1.03e-124 - - - L - - - DNA integration
HPKLIDJL_01033 4.46e-32 - - - GM - - - NmrA-like family
HPKLIDJL_01034 8.96e-20 - - - GM - - - NAD(P)H-binding
HPKLIDJL_01037 1.1e-26 - - - L ko:K07459 - ko00000 AAA ATPase domain
HPKLIDJL_01039 3.83e-163 - - - L - - - Integrase core domain
HPKLIDJL_01040 4.06e-58 - - - - - - - -
HPKLIDJL_01041 8.09e-42 - - - - - - - -
HPKLIDJL_01042 1.36e-81 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
HPKLIDJL_01044 5.47e-79 - - - V - - - ATPases associated with a variety of cellular activities
HPKLIDJL_01045 1.17e-253 - - - L - - - Transposase and inactivated derivatives, IS30 family
HPKLIDJL_01046 1.31e-25 - - - V - - - ATPases associated with a variety of cellular activities
HPKLIDJL_01047 2.25e-90 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HPKLIDJL_01048 6.31e-97 - - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
HPKLIDJL_01049 0.000351 - - - K - - - Transcriptional
HPKLIDJL_01050 4.14e-135 - - - K ko:K07467 - ko00000 Replication initiation factor
HPKLIDJL_01051 1.98e-39 - - - - - - - -
HPKLIDJL_01052 3.25e-132 - - - L - - - DNA integration
HPKLIDJL_01053 1.71e-205 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HPKLIDJL_01054 4.82e-179 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPKLIDJL_01055 5.14e-212 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
HPKLIDJL_01056 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HPKLIDJL_01057 3.18e-198 - - - D - - - DNA integration
HPKLIDJL_01058 9.3e-220 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HPKLIDJL_01059 2.14e-133 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HPKLIDJL_01060 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HPKLIDJL_01061 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HPKLIDJL_01062 5.1e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
HPKLIDJL_01063 5.36e-219 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
HPKLIDJL_01064 7.86e-92 - - - S - - - Belongs to the HesB IscA family
HPKLIDJL_01065 4.65e-100 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HPKLIDJL_01066 3.6e-122 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HPKLIDJL_01067 5.48e-106 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HPKLIDJL_01068 7.19e-314 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HPKLIDJL_01069 3.75e-307 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
HPKLIDJL_01070 0.0 - - - EP - - - Psort location Cytoplasmic, score
HPKLIDJL_01072 0.0 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HPKLIDJL_01073 2.68e-152 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HPKLIDJL_01074 4.3e-312 yhjX - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
HPKLIDJL_01075 6.21e-21 ycnB - - U - - - Belongs to the major facilitator superfamily
HPKLIDJL_01076 4.76e-290 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HPKLIDJL_01077 0.0 - - - E ko:K03758 - ko00000,ko02000 Amino acid permease
HPKLIDJL_01078 5.43e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HPKLIDJL_01079 6.07e-138 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HPKLIDJL_01080 2.77e-10 - - - C - - - Domain of unknown function (DUF4145)
HPKLIDJL_01081 8.28e-292 - - - L - - - MULE transposase domain
HPKLIDJL_01082 5.34e-89 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HPKLIDJL_01083 2.81e-117 - - - S - - - Fic/DOC family
HPKLIDJL_01084 1.32e-125 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
HPKLIDJL_01085 6.8e-154 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
HPKLIDJL_01086 7.86e-118 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
HPKLIDJL_01087 1.46e-88 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
HPKLIDJL_01088 2.89e-136 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
HPKLIDJL_01089 1.28e-274 - - - E - - - Aminotransferase
HPKLIDJL_01092 3.03e-44 - - - S - - - Phage minor capsid protein 2
HPKLIDJL_01093 9.86e-93 - - - S - - - Phage minor capsid protein 2
HPKLIDJL_01094 1.82e-209 - - - I - - - alpha/beta hydrolase fold
HPKLIDJL_01095 5.49e-124 - 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HPKLIDJL_01097 5.05e-207 - - - S - - - DUF218 domain
HPKLIDJL_01098 8.03e-214 yvgN - - C - - - Aldo keto reductase
HPKLIDJL_01099 1.85e-105 - - - S - - - ECF-type riboflavin transporter, S component
HPKLIDJL_01100 4.49e-194 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
HPKLIDJL_01101 1.46e-302 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate/isopropylmalate dehydrogenase
HPKLIDJL_01102 1.08e-78 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
HPKLIDJL_01103 7.19e-260 xerS - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
HPKLIDJL_01104 2.4e-230 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPKLIDJL_01105 4.21e-287 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HPKLIDJL_01106 3.37e-249 bdhA 1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4 - C ko:K00004,ko:K00008,ko:K00098 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
HPKLIDJL_01107 3.35e-89 - - - C - - - Zinc-binding dehydrogenase
HPKLIDJL_01108 2.04e-74 - - - C - - - Zinc-binding dehydrogenase
HPKLIDJL_01109 7.95e-132 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
HPKLIDJL_01110 1.33e-180 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKLIDJL_01111 1.8e-138 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HPKLIDJL_01112 2.84e-209 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
HPKLIDJL_01113 1.21e-99 ywnA - - K - - - Transcriptional regulator
HPKLIDJL_01114 5.23e-97 - - - O ko:K07397 - ko00000 OsmC-like protein
HPKLIDJL_01115 3.92e-97 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HPKLIDJL_01116 2.66e-33 - - - C - - - Flavodoxin
HPKLIDJL_01117 1.39e-39 - - - GM - - - NmrA-like family
HPKLIDJL_01118 4.58e-59 - - - K - - - transcriptional regulator
HPKLIDJL_01119 6.26e-138 - - - L - - - Integrase
HPKLIDJL_01120 1.51e-88 - - - I - - - Alpha/beta hydrolase family
HPKLIDJL_01121 1.09e-169 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HPKLIDJL_01122 3.41e-16 citR - - K - - - sugar-binding domain protein
HPKLIDJL_01123 1.6e-77 citR - - K - - - sugar-binding domain protein
HPKLIDJL_01124 3.63e-235 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
HPKLIDJL_01126 1.89e-205 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HPKLIDJL_01127 8.78e-100 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HPKLIDJL_01128 6.51e-45 - - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
HPKLIDJL_01129 1.34e-74 yuxO - - Q - - - Thioesterase superfamily
HPKLIDJL_01130 1.2e-201 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HPKLIDJL_01131 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HPKLIDJL_01132 3.39e-275 - - - G - - - Transporter, major facilitator family protein
HPKLIDJL_01133 1.07e-264 adh 1.1.1.1 - C ko:K00001,ko:K18369 ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
HPKLIDJL_01134 3.76e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HPKLIDJL_01135 9.99e-216 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HPKLIDJL_01136 1.65e-53 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
HPKLIDJL_01137 2.21e-310 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
HPKLIDJL_01138 5.37e-230 - - - K - - - WYL domain
HPKLIDJL_01139 2.29e-88 - - - S - - - pyridoxamine 5-phosphate
HPKLIDJL_01140 7.18e-45 - - - - - - - -
HPKLIDJL_01142 2.65e-84 - - - - - - - -
HPKLIDJL_01144 1.3e-81 yicL - - EG - - - EamA-like transporter family
HPKLIDJL_01145 5.01e-12 - - - S - - - Domain of unknown function (DUF4352)
HPKLIDJL_01146 1.37e-82 - - - S - - - Domain of unknown function (DUF4352)
HPKLIDJL_01147 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HPKLIDJL_01148 6.15e-211 - - - K - - - LysR substrate binding domain
HPKLIDJL_01149 2.34e-205 rssA - - S - - - Phospholipase, patatin family
HPKLIDJL_01150 1.33e-273 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HPKLIDJL_01151 5.43e-238 XK27_12525 - - S - - - AI-2E family transporter
HPKLIDJL_01152 2.08e-159 - - - S ko:K07090 - ko00000 membrane transporter protein
HPKLIDJL_01153 8.23e-117 pgpA - - I - - - Phosphatidylglycerophosphatase A
HPKLIDJL_01154 2.37e-249 flp - - V - - - Beta-lactamase
HPKLIDJL_01155 1.95e-291 - - - - - - - -
HPKLIDJL_01157 3.06e-206 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HPKLIDJL_01158 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPKLIDJL_01159 7.01e-212 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
HPKLIDJL_01160 3.89e-209 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
HPKLIDJL_01161 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HPKLIDJL_01163 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
HPKLIDJL_01165 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HPKLIDJL_01166 1.84e-302 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HPKLIDJL_01167 4.81e-08 - - - S - - - SNARE associated Golgi protein
HPKLIDJL_01168 3.37e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
HPKLIDJL_01169 8.73e-129 - - - K - - - Virulence activator alpha C-term
HPKLIDJL_01170 1.26e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
HPKLIDJL_01172 2.5e-282 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
HPKLIDJL_01174 3.12e-185 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HPKLIDJL_01175 2.22e-196 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HPKLIDJL_01176 4.93e-287 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
HPKLIDJL_01180 2.81e-10 - - - S ko:K07334 - ko00000,ko02048 RelE-like toxin of type II toxin-antitoxin system HigB
HPKLIDJL_01181 2.42e-43 axe - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
HPKLIDJL_01182 5.61e-41 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
HPKLIDJL_01183 2.2e-07 tdh 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
HPKLIDJL_01184 1.66e-100 - - - E - - - Zinc-binding dehydrogenase
HPKLIDJL_01185 5.81e-47 tdh 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
HPKLIDJL_01186 0.0 guaD 3.5.4.3 - F ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Amidohydrolase family
HPKLIDJL_01187 3.81e-274 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HPKLIDJL_01190 1.89e-74 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Low molecular weight phosphotyrosine protein phosphatase
HPKLIDJL_01191 3.45e-84 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HPKLIDJL_01192 1.03e-105 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_01193 2.34e-303 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_01194 9.68e-50 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HPKLIDJL_01195 1.5e-72 rmeB - - K - - - transcriptional regulator, MerR family
HPKLIDJL_01196 3.1e-170 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
HPKLIDJL_01197 2.4e-144 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKLIDJL_01198 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HPKLIDJL_01199 4.76e-28 - - - S - - - Protein of unknown function (DUF4256)
HPKLIDJL_01201 3.64e-113 - - - L ko:K07497 - ko00000 hmm pf00665
HPKLIDJL_01202 2.24e-54 - - - L - - - Helix-turn-helix domain
HPKLIDJL_01203 4.54e-25 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HPKLIDJL_01204 8.28e-292 - - - L - - - MULE transposase domain
HPKLIDJL_01206 5.77e-72 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
HPKLIDJL_01207 0.0 - - - L - - - Type III restriction enzyme, res subunit
HPKLIDJL_01209 3.56e-130 - - - K - - - DNA-templated transcription, initiation
HPKLIDJL_01210 8.28e-292 - - - L - - - MULE transposase domain
HPKLIDJL_01212 9.64e-109 - - - L - - - MULE transposase domain
HPKLIDJL_01213 3.98e-82 - - - L - - - Integrase core domain
HPKLIDJL_01214 3.98e-129 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HPKLIDJL_01215 2.14e-34 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HPKLIDJL_01216 0.0 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HPKLIDJL_01217 1.54e-246 - - - L - - - Transposase and inactivated derivatives, IS30 family
HPKLIDJL_01218 1.22e-84 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HPKLIDJL_01219 1.25e-05 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HPKLIDJL_01220 5.74e-34 is18 - - L - - - Integrase core domain
HPKLIDJL_01221 4.93e-54 repA - - S - - - Replication initiator protein A
HPKLIDJL_01222 1.28e-71 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPKLIDJL_01223 1.48e-73 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPKLIDJL_01224 4.17e-89 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HPKLIDJL_01225 6.33e-133 - - - K - - - Acetyltransferase (GNAT) family
HPKLIDJL_01226 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
HPKLIDJL_01227 1.75e-165 - - - C - - - Oxidoreductase NAD-binding domain
HPKLIDJL_01228 1.35e-106 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_01229 5.74e-304 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_01230 3.18e-212 - - - GK - - - ROK family
HPKLIDJL_01231 1.12e-54 - - - - - - - -
HPKLIDJL_01232 1.03e-106 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
HPKLIDJL_01234 5.17e-100 - 3.6.3.6 - P ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 ATPase, P-type transporting, HAD superfamily, subfamily IC
HPKLIDJL_01235 1.04e-218 - - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional activator, Rgg GadR MutR family
HPKLIDJL_01236 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HPKLIDJL_01237 2.34e-301 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
HPKLIDJL_01238 8.05e-233 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
HPKLIDJL_01239 1.59e-80 - - - - - - - -
HPKLIDJL_01240 4.2e-284 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HPKLIDJL_01241 1.69e-124 - - - V - - - VanZ like family
HPKLIDJL_01242 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HPKLIDJL_01243 7.88e-62 - - - S ko:K07118 - ko00000 NAD(P)H-binding
HPKLIDJL_01244 1.52e-82 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
HPKLIDJL_01245 1.01e-99 - - - - - - - -
HPKLIDJL_01246 1.24e-234 - - - - - - - -
HPKLIDJL_01247 4.92e-305 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_01248 3.19e-105 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_01249 7.16e-163 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
HPKLIDJL_01250 1.77e-131 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 Nitrate reductase delta subunit
HPKLIDJL_01251 0.0 - 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
HPKLIDJL_01252 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HPKLIDJL_01253 6.23e-244 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
HPKLIDJL_01254 2.18e-112 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
HPKLIDJL_01255 3.66e-294 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
HPKLIDJL_01256 5.7e-108 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HPKLIDJL_01257 1.01e-127 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HPKLIDJL_01258 6.94e-54 - - - - - - - -
HPKLIDJL_01259 8.62e-102 nreA - - T ko:K10851 ko02020,map02020 ko00000,ko00001 GAF domain
HPKLIDJL_01260 1.14e-239 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
HPKLIDJL_01261 1.83e-150 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
HPKLIDJL_01262 1.99e-53 - - - - - - - -
HPKLIDJL_01263 1.7e-235 - - - - - - - -
HPKLIDJL_01264 3.49e-217 - - - H - - - geranyltranstransferase activity
HPKLIDJL_01266 2.5e-172 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HPKLIDJL_01267 4.73e-210 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HPKLIDJL_01268 2.36e-77 - - - S - - - Iron-sulfur cluster assembly protein
HPKLIDJL_01269 7.73e-277 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Major Facilitator Superfamily
HPKLIDJL_01270 1.67e-249 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HPKLIDJL_01271 2.34e-47 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
HPKLIDJL_01272 7.91e-95 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
HPKLIDJL_01273 8.22e-76 - - - S - - - Flavodoxin
HPKLIDJL_01274 5.1e-219 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HPKLIDJL_01275 2.6e-183 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HPKLIDJL_01276 1.55e-292 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HPKLIDJL_01277 3.62e-72 yitW - - S - - - Iron-sulfur cluster assembly protein
HPKLIDJL_01278 1.04e-26 - - - S - - - Domain of unknown function (DUF1858)
HPKLIDJL_01279 0.0 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
HPKLIDJL_01280 9.64e-183 - - - EG - - - EamA-like transporter family
HPKLIDJL_01281 9.01e-314 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HPKLIDJL_01282 7.17e-237 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HPKLIDJL_01283 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
HPKLIDJL_01284 5.04e-109 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
HPKLIDJL_01285 2.6e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HPKLIDJL_01286 1.09e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
HPKLIDJL_01287 2.21e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
HPKLIDJL_01288 8.17e-45 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
HPKLIDJL_01289 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
HPKLIDJL_01290 1.25e-31 - - - S - - - Virus attachment protein p12 family
HPKLIDJL_01291 6.35e-201 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HPKLIDJL_01292 1.81e-226 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HPKLIDJL_01293 2.41e-235 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPKLIDJL_01294 9.06e-279 aspB3 - - E - - - DegT/DnrJ/EryC1/StrS aminotransferase family
HPKLIDJL_01295 3.71e-117 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HPKLIDJL_01296 1.01e-251 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
HPKLIDJL_01297 3.33e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HPKLIDJL_01298 9.4e-133 - - - - - - - -
HPKLIDJL_01299 7.65e-272 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HPKLIDJL_01300 7.56e-15 aroH 5.4.99.5 - E ko:K04516 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
HPKLIDJL_01301 2.47e-273 - - - G - - - Major Facilitator Superfamily
HPKLIDJL_01303 5.39e-46 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HPKLIDJL_01304 6.19e-264 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HPKLIDJL_01306 6.41e-196 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
HPKLIDJL_01307 7.83e-205 - - - GM - - - NAD(P)H-binding
HPKLIDJL_01308 4.19e-203 - - - S - - - Alpha beta hydrolase
HPKLIDJL_01309 1.38e-301 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
HPKLIDJL_01311 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HPKLIDJL_01312 1.47e-66 - - - - - - - -
HPKLIDJL_01313 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HPKLIDJL_01315 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HPKLIDJL_01316 4.64e-36 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
HPKLIDJL_01317 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
HPKLIDJL_01318 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HPKLIDJL_01319 9.17e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HPKLIDJL_01320 2.02e-305 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPKLIDJL_01321 3.52e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPKLIDJL_01322 1.53e-214 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HPKLIDJL_01323 3.08e-202 - - - EGP ko:K18934 - ko00000,ko02000 Major Facilitator Superfamily
HPKLIDJL_01324 1.54e-272 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HPKLIDJL_01325 0.0 yhdP - - S - - - Transporter associated domain
HPKLIDJL_01326 1.97e-15 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
HPKLIDJL_01327 2.53e-135 - - - S - - - Type III restriction enzyme, res subunit
HPKLIDJL_01329 1.23e-99 - - - S - - - N-methyltransferase activity
HPKLIDJL_01330 9.23e-245 - - - S - - - Domain of unknown function (DUF3440)
HPKLIDJL_01334 1.43e-119 - - - M - - - hydrolase, family 25
HPKLIDJL_01340 2.71e-34 - - - S - - - GDSL-like Lipase/Acylhydrolase
HPKLIDJL_01343 1.09e-55 - - - - - - - -
HPKLIDJL_01344 1.26e-189 rny - - D ko:K12088,ko:K18682 ko03018,ko05120,map03018,map05120 ko00000,ko00001,ko00002,ko01000,ko02044,ko03019 peptidase
HPKLIDJL_01345 2.21e-100 - - - S - - - Phage tail protein
HPKLIDJL_01346 2.75e-293 - - - L - - - Phage tail tape measure protein TP901
HPKLIDJL_01348 9.85e-48 - - - S - - - Phage tail tube protein
HPKLIDJL_01349 1.11e-30 - - - - - - - -
HPKLIDJL_01350 4.57e-25 - - - - - - - -
HPKLIDJL_01351 2.54e-43 - - - S - - - Phage head-tail joining protein
HPKLIDJL_01352 3.06e-40 - - - S - - - Phage gp6-like head-tail connector protein
HPKLIDJL_01353 5.33e-152 - - - S - - - Phage capsid family
HPKLIDJL_01354 1.61e-100 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
HPKLIDJL_01355 7.19e-183 - - - S - - - portal protein
HPKLIDJL_01357 0.0 - - - S - - - Phage Terminase
HPKLIDJL_01358 7.69e-52 - - - L - - - Phage terminase, small subunit
HPKLIDJL_01359 4.31e-43 - - - L - - - HNH nucleases
HPKLIDJL_01361 3.79e-13 - - - S - - - hydrolase activity
HPKLIDJL_01367 4.29e-08 - - - - - - - -
HPKLIDJL_01373 1.46e-55 rusA - - L - - - Endodeoxyribonuclease RusA
HPKLIDJL_01377 3.37e-14 - - - K - - - Cro/C1-type HTH DNA-binding domain
HPKLIDJL_01379 2.27e-50 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
HPKLIDJL_01380 1.28e-146 - - - S - - - calcium ion binding
HPKLIDJL_01381 5.09e-50 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HPKLIDJL_01382 1.74e-150 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
HPKLIDJL_01383 5.7e-225 - - - L ko:K07455 - ko00000,ko03400 RecT family
HPKLIDJL_01390 8.62e-119 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
HPKLIDJL_01391 8e-05 - - - K ko:K07729 - ko00000,ko03000 DNA-binding helix-turn-helix protein
HPKLIDJL_01392 1.43e-65 - 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Peptidase S24-like
HPKLIDJL_01394 1.59e-124 int3 - - L - - - Belongs to the 'phage' integrase family
HPKLIDJL_01395 1.05e-245 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
HPKLIDJL_01396 7.1e-59 rlrB - - K - - - LysR substrate binding domain protein
HPKLIDJL_01397 3.33e-42 rlrB - - K - - - LysR substrate binding domain protein
HPKLIDJL_01398 2.12e-275 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HPKLIDJL_01399 1.67e-248 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HPKLIDJL_01400 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
HPKLIDJL_01401 6.74e-270 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HPKLIDJL_01402 1.75e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
HPKLIDJL_01403 2.83e-231 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
HPKLIDJL_01404 5.26e-14 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
HPKLIDJL_01405 1.21e-41 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
HPKLIDJL_01406 7.76e-72 azlD - - E - - - Branched-chain amino acid transport
HPKLIDJL_01407 1.63e-156 azlC - - E - - - azaleucine resistance protein AzlC
HPKLIDJL_01408 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
HPKLIDJL_01409 1.24e-298 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HPKLIDJL_01410 1.15e-201 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HPKLIDJL_01411 8.44e-128 - - - K - - - Acetyltransferase (GNAT) domain
HPKLIDJL_01412 1.24e-146 ylbE - - GM - - - NAD(P)H-binding
HPKLIDJL_01413 2.5e-153 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HPKLIDJL_01414 7.11e-172 yaaA - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HPKLIDJL_01415 8.01e-129 - - - - - - - -
HPKLIDJL_01416 6.96e-206 - - - S - - - EDD domain protein, DegV family
HPKLIDJL_01417 0.0 FbpA - - K - - - Fibronectin-binding protein
HPKLIDJL_01418 2e-304 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_01419 1.06e-17 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_01420 2.19e-153 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HPKLIDJL_01423 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HPKLIDJL_01424 4.18e-115 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HPKLIDJL_01425 4.36e-155 - 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
HPKLIDJL_01426 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HPKLIDJL_01427 2.43e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
HPKLIDJL_01428 4.45e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HPKLIDJL_01429 1.27e-99 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HPKLIDJL_01430 1e-91 esbA - - S - - - Family of unknown function (DUF5322)
HPKLIDJL_01431 3.77e-93 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
HPKLIDJL_01432 2.85e-141 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
HPKLIDJL_01433 2.41e-199 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HPKLIDJL_01434 2.37e-152 yckA - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HPKLIDJL_01435 8.33e-61 - - - L ko:K07483 - ko00000 Transposase
HPKLIDJL_01436 8.28e-292 - - - L - - - MULE transposase domain
HPKLIDJL_01438 1.04e-150 - - - L ko:K07497 - ko00000 Integrase core domain
HPKLIDJL_01440 6.72e-238 - - - L - - - PFAM Integrase catalytic region
HPKLIDJL_01441 4.71e-56 - - - V - - - HNH endonuclease
HPKLIDJL_01442 8.28e-292 - - - L - - - MULE transposase domain
HPKLIDJL_01443 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
HPKLIDJL_01444 5.25e-255 arcD - - S - - - C4-dicarboxylate anaerobic carrier
HPKLIDJL_01445 5.12e-241 arcT - - E - - - Dipeptidase
HPKLIDJL_01446 3.68e-278 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HPKLIDJL_01447 9.95e-108 - - - F - - - Hydrolase, NUDIX family
HPKLIDJL_01448 5.09e-270 - - - S ko:K06915 - ko00000 AAA-like domain
HPKLIDJL_01449 0.0 fusA1 - - J - - - elongation factor G
HPKLIDJL_01450 6.22e-243 - - - L ko:K07482 - ko00000 Helix-turn-helix domain
HPKLIDJL_01451 2.08e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HPKLIDJL_01452 3.1e-144 ypsA - - S - - - Belongs to the UPF0398 family
HPKLIDJL_01453 5.72e-151 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HPKLIDJL_01454 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
HPKLIDJL_01455 6.64e-205 - - - EG - - - EamA-like transporter family
HPKLIDJL_01456 5.51e-242 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
HPKLIDJL_01457 7.77e-183 ypuA - - S - - - Protein of unknown function (DUF1002)
HPKLIDJL_01458 4.14e-173 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
HPKLIDJL_01459 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HPKLIDJL_01460 6.66e-115 ypmB - - S - - - Protein conserved in bacteria
HPKLIDJL_01461 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HPKLIDJL_01462 2.17e-214 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
HPKLIDJL_01463 3.68e-231 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
HPKLIDJL_01464 4.77e-270 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
HPKLIDJL_01465 5.29e-263 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HPKLIDJL_01466 5.62e-120 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HPKLIDJL_01467 7.55e-130 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
HPKLIDJL_01468 2.42e-122 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HPKLIDJL_01469 2.23e-116 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HPKLIDJL_01470 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
HPKLIDJL_01471 5.29e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HPKLIDJL_01472 2.26e-213 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HPKLIDJL_01473 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HPKLIDJL_01474 1.25e-265 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HPKLIDJL_01475 1.55e-310 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HPKLIDJL_01476 3.99e-231 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HPKLIDJL_01477 1.48e-72 ycsI - - S - - - Protein of unknown function (DUF1445)
HPKLIDJL_01478 0.0 - 2.4.1.5 GH13 G ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
HPKLIDJL_01479 5.86e-61 - - - L ko:K07483 - ko00000 Transposase
HPKLIDJL_01480 1.48e-216 - - - L ko:K07497 - ko00000 Integrase core domain
HPKLIDJL_01481 1e-202 - - - L - - - Transposase and inactivated derivatives, IS30 family
HPKLIDJL_01482 4.78e-141 - - - L ko:K07482 - ko00000 Helix-turn-helix domain
HPKLIDJL_01483 6.59e-76 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HPKLIDJL_01484 0.0 - - - E ko:K03294 - ko00000 Amino Acid
HPKLIDJL_01485 2.22e-182 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HPKLIDJL_01486 1.52e-114 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HPKLIDJL_01487 9.17e-54 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HPKLIDJL_01488 4.94e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HPKLIDJL_01489 2.78e-158 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HPKLIDJL_01490 1.28e-176 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPKLIDJL_01491 1.74e-195 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
HPKLIDJL_01492 4.79e-196 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HPKLIDJL_01493 5.7e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HPKLIDJL_01494 2.06e-169 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
HPKLIDJL_01495 1.01e-25 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HPKLIDJL_01496 8.28e-292 - - - L - - - MULE transposase domain
HPKLIDJL_01499 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HPKLIDJL_01500 1.15e-119 - - - - - - - -
HPKLIDJL_01501 4.43e-221 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HPKLIDJL_01502 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HPKLIDJL_01503 1.72e-75 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HPKLIDJL_01504 4.56e-293 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HPKLIDJL_01505 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HPKLIDJL_01506 3.99e-166 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HPKLIDJL_01507 1.65e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HPKLIDJL_01508 2.2e-215 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HPKLIDJL_01509 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HPKLIDJL_01510 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
HPKLIDJL_01511 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
HPKLIDJL_01512 1e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HPKLIDJL_01513 9.12e-161 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HPKLIDJL_01514 1.1e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HPKLIDJL_01515 2.53e-210 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HPKLIDJL_01516 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HPKLIDJL_01517 1.68e-169 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HPKLIDJL_01518 5.57e-316 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HPKLIDJL_01519 5.61e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HPKLIDJL_01520 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HPKLIDJL_01521 2.07e-282 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HPKLIDJL_01522 1.9e-61 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HPKLIDJL_01523 1.03e-146 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HPKLIDJL_01525 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HPKLIDJL_01526 4.92e-99 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HPKLIDJL_01527 1.14e-189 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HPKLIDJL_01528 1.39e-200 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HPKLIDJL_01529 1.64e-25 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPKLIDJL_01530 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPKLIDJL_01531 2e-206 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HPKLIDJL_01532 1.98e-91 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HPKLIDJL_01533 2.1e-94 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
HPKLIDJL_01534 4.18e-263 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HPKLIDJL_01535 8.74e-62 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HPKLIDJL_01536 1.2e-70 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
HPKLIDJL_01537 1.89e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HPKLIDJL_01538 1.29e-148 - - - K - - - Transcriptional regulator
HPKLIDJL_01540 9.76e-172 - - - - - - - -
HPKLIDJL_01541 1.55e-266 - - - M - - - hydrolase, family 25
HPKLIDJL_01542 1.53e-39 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
HPKLIDJL_01549 3.32e-85 spoIVFA - GT2,GT4 D ko:K05802,ko:K06401,ko:K20444,ko:K22051 - ko00000,ko01000,ko01005,ko02000 peptidase
HPKLIDJL_01550 0.0 - - - M - - - Prophage endopeptidase tail
HPKLIDJL_01551 3.91e-210 - - - S - - - Phage tail protein
HPKLIDJL_01552 0.0 - - - L - - - Phage tail tape measure protein TP901
HPKLIDJL_01553 3.83e-68 - - - S - - - Phage tail assembly chaperone proteins, TAC
HPKLIDJL_01554 1.3e-145 - - - S - - - Phage tail tube protein
HPKLIDJL_01556 3.29e-09 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HPKLIDJL_01558 7.49e-64 - - - - - - - -
HPKLIDJL_01559 3.73e-231 - - - G ko:K06904 - ko00000 Phage capsid family
HPKLIDJL_01560 3.45e-239 - - - S - - - Phage portal protein
HPKLIDJL_01562 0.0 - - - S - - - Phage Terminase
HPKLIDJL_01563 8.71e-101 - - - L - - - Phage terminase, small subunit
HPKLIDJL_01564 1.27e-54 - - - - - - - -
HPKLIDJL_01565 1.01e-168 - - - - - - - -
HPKLIDJL_01569 1.47e-32 - - - L - - - Psort location Cytoplasmic, score
HPKLIDJL_01570 3.58e-124 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HPKLIDJL_01571 2.82e-198 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
HPKLIDJL_01572 2.55e-213 - - - L ko:K07455 - ko00000,ko03400 RecT family
HPKLIDJL_01580 9.39e-124 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
HPKLIDJL_01582 1.38e-19 - - - K - - - Helix-turn-helix
HPKLIDJL_01587 5.04e-257 - - - S - - - Phage integrase family
HPKLIDJL_01588 3.15e-120 - - - S - - - Protein conserved in bacteria
HPKLIDJL_01589 2.34e-226 - - - - - - - -
HPKLIDJL_01590 5.44e-201 - - - - - - - -
HPKLIDJL_01591 4.76e-19 - - - - - - - -
HPKLIDJL_01592 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HPKLIDJL_01593 6.29e-221 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HPKLIDJL_01594 3.51e-33 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
HPKLIDJL_01595 5.91e-93 yqhL - - P - - - Rhodanese-like protein
HPKLIDJL_01596 1.83e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HPKLIDJL_01597 1.14e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
HPKLIDJL_01598 7.12e-150 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
HPKLIDJL_01599 4.45e-128 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HPKLIDJL_01600 7.58e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HPKLIDJL_01601 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HPKLIDJL_01602 0.0 - - - S - - - membrane
HPKLIDJL_01603 3.01e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HPKLIDJL_01604 2.41e-150 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HPKLIDJL_01605 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HPKLIDJL_01606 2.12e-251 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HPKLIDJL_01607 1.44e-78 yodB - - K - - - Transcriptional regulator, HxlR family
HPKLIDJL_01608 5.12e-117 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HPKLIDJL_01609 1.84e-180 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPKLIDJL_01610 8.13e-62 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HPKLIDJL_01611 1.13e-196 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HPKLIDJL_01612 6.2e-240 - - - L - - - PFAM Integrase catalytic region
HPKLIDJL_01613 4.54e-91 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HPKLIDJL_01614 1.88e-298 - - - V - - - MatE
HPKLIDJL_01615 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HPKLIDJL_01616 1.38e-155 csrR - - K - - - response regulator
HPKLIDJL_01617 7.89e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HPKLIDJL_01618 4.62e-125 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HPKLIDJL_01619 1.01e-274 ylbM - - S - - - Belongs to the UPF0348 family
HPKLIDJL_01620 1.57e-181 yqeM - - Q - - - Methyltransferase
HPKLIDJL_01621 1.14e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HPKLIDJL_01622 5.53e-145 yqeK - - H - - - Hydrolase, HD family
HPKLIDJL_01623 4.63e-120 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HPKLIDJL_01624 1.38e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
HPKLIDJL_01625 2.29e-275 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
HPKLIDJL_01626 6.88e-125 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
HPKLIDJL_01627 1.51e-32 - - - S - - - Protein of unknown function (DUF1275)
HPKLIDJL_01628 3.35e-22 - - - S - - - Protein of unknown function (DUF1275)
HPKLIDJL_01629 4.67e-75 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HPKLIDJL_01630 5.22e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HPKLIDJL_01631 6.95e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HPKLIDJL_01632 2.66e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HPKLIDJL_01633 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
HPKLIDJL_01634 3.44e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HPKLIDJL_01635 8.04e-135 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HPKLIDJL_01636 7.57e-208 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HPKLIDJL_01637 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HPKLIDJL_01638 1.14e-178 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
HPKLIDJL_01639 1.24e-146 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HPKLIDJL_01640 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HPKLIDJL_01641 9.14e-152 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HPKLIDJL_01642 1.53e-72 ytpP - - CO - - - Thioredoxin
HPKLIDJL_01643 6.83e-76 - - - S - - - Small secreted protein
HPKLIDJL_01644 9.51e-161 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HPKLIDJL_01645 5.42e-275 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HPKLIDJL_01646 3.68e-171 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKLIDJL_01647 4.29e-101 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
HPKLIDJL_01649 6.67e-192 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HPKLIDJL_01650 2.59e-230 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
HPKLIDJL_01651 3.95e-73 yheA - - S - - - Belongs to the UPF0342 family
HPKLIDJL_01652 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HPKLIDJL_01653 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HPKLIDJL_01655 4.86e-53 - - - - - - - -
HPKLIDJL_01657 7.65e-260 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
HPKLIDJL_01658 1.12e-136 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
HPKLIDJL_01659 7.08e-310 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HPKLIDJL_01660 1.13e-133 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
HPKLIDJL_01661 7.52e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HPKLIDJL_01662 9.96e-82 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HPKLIDJL_01663 2.89e-152 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
HPKLIDJL_01664 5.03e-232 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
HPKLIDJL_01665 4.91e-143 - - - - - - - -
HPKLIDJL_01666 3.06e-150 dgk2 - - F - - - deoxynucleoside kinase
HPKLIDJL_01667 1.09e-238 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HPKLIDJL_01668 0.0 - - - S - - - Putative peptidoglycan binding domain
HPKLIDJL_01669 2.01e-113 - - - T - - - Belongs to the universal stress protein A family
HPKLIDJL_01670 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
HPKLIDJL_01671 2.29e-196 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HPKLIDJL_01672 2.84e-82 - - - S - - - Domain of unknown function DUF302
HPKLIDJL_01673 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HPKLIDJL_01674 8.13e-56 - - - - - - - -
HPKLIDJL_01675 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HPKLIDJL_01676 2.93e-163 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HPKLIDJL_01677 6.23e-286 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HPKLIDJL_01678 6.54e-181 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HPKLIDJL_01679 3.78e-271 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HPKLIDJL_01680 3.23e-64 - - - - - - - -
HPKLIDJL_01681 1.3e-22 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HPKLIDJL_01682 0.0 - - - EGP - - - Major Facilitator
HPKLIDJL_01683 2.95e-110 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HPKLIDJL_01684 1.83e-313 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HPKLIDJL_01685 1.59e-30 - - - - - - - -
HPKLIDJL_01688 5.99e-306 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_01689 1.03e-105 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_01690 1.07e-148 - - - K - - - Transcriptional regulator, TetR family
HPKLIDJL_01691 2.79e-102 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HPKLIDJL_01692 3.6e-112 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
HPKLIDJL_01693 5.28e-91 - - - M - - - LysM domain protein
HPKLIDJL_01694 2.27e-251 adh 1.1.1.1 - C ko:K00001,ko:K18369 ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
HPKLIDJL_01695 1.85e-301 - - - F ko:K03458 - ko00000 Permease
HPKLIDJL_01696 1.25e-207 - - - O - - - Uncharacterized protein family (UPF0051)
HPKLIDJL_01697 2.56e-145 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPKLIDJL_01698 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
HPKLIDJL_01699 1.11e-145 arpJ - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HPKLIDJL_01700 3.37e-183 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HPKLIDJL_01701 9.58e-19 ebrB - - U ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HPKLIDJL_01702 3.13e-06 - - - K - - - Transcriptional regulator
HPKLIDJL_01713 8.34e-101 - - - - - - - -
HPKLIDJL_01716 2.81e-53 - - - S - - - Protein of unknown function (DUF1797)
HPKLIDJL_01717 8.01e-231 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HPKLIDJL_01718 1.28e-253 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HPKLIDJL_01719 5.62e-294 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HPKLIDJL_01720 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HPKLIDJL_01721 2.14e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
HPKLIDJL_01722 2.41e-07 - - - - - - - -
HPKLIDJL_01723 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
HPKLIDJL_01724 5.03e-166 - - - F - - - NUDIX domain
HPKLIDJL_01725 8.61e-143 pncA - - Q - - - Isochorismatase family
HPKLIDJL_01726 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HPKLIDJL_01727 8.54e-63 - - - L - - - Helix-turn-helix domain
HPKLIDJL_01728 2.21e-114 - - - L ko:K07497 - ko00000 hmm pf00665
HPKLIDJL_01729 8.07e-126 - - - S - - - Pfam:DUF3816
HPKLIDJL_01730 3.86e-181 - - - G - - - MucBP domain
HPKLIDJL_01731 2.46e-175 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HPKLIDJL_01732 4.44e-208 - - - EG - - - EamA-like transporter family
HPKLIDJL_01733 2.77e-314 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
HPKLIDJL_01734 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HPKLIDJL_01738 2.32e-201 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKLIDJL_01739 8.46e-84 - - - K - - - Transcriptional regulator, GntR family
HPKLIDJL_01740 1.6e-220 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HPKLIDJL_01741 3.77e-102 - - - S - - - Bacterial membrane protein, YfhO
HPKLIDJL_01742 2.15e-266 - - - S - - - Psort location CytoplasmicMembrane, score
HPKLIDJL_01743 1.16e-188 ykoT - - M - - - Glycosyl transferase family 2
HPKLIDJL_01744 3.67e-127 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
HPKLIDJL_01745 2.62e-119 - - - M - - - transferase activity, transferring glycosyl groups
HPKLIDJL_01746 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HPKLIDJL_01747 5.22e-211 ykoT - - M - - - Glycosyl transferase family 2
HPKLIDJL_01748 3.06e-218 yueF - - S - - - AI-2E family transporter
HPKLIDJL_01749 9.36e-204 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
HPKLIDJL_01750 8.03e-10 - - - - - - - -
HPKLIDJL_01751 2.2e-119 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
HPKLIDJL_01752 7.29e-71 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HPKLIDJL_01753 1.49e-279 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HPKLIDJL_01754 1.54e-253 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HPKLIDJL_01755 5.66e-280 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HPKLIDJL_01756 4.76e-290 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HPKLIDJL_01757 1.21e-62 cps3I - - G - - - Acyltransferase family
HPKLIDJL_01758 1.34e-39 - - - M - - - biosynthesis protein
HPKLIDJL_01759 3.84e-116 cps3F - - - - - - -
HPKLIDJL_01760 1.15e-189 cps1D - - M - - - Domain of unknown function (DUF4422)
HPKLIDJL_01761 1.73e-152 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
HPKLIDJL_01762 4.13e-188 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
HPKLIDJL_01764 4.37e-43 - - - S - - - Protein of unknown function (DUF2922)
HPKLIDJL_01765 9.71e-191 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HPKLIDJL_01766 0.0 XK27_08315 - - M - - - Sulfatase
HPKLIDJL_01767 4.77e-214 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
HPKLIDJL_01768 1.66e-101 ykuP - - C ko:K03839 - ko00000 Flavodoxin
HPKLIDJL_01769 1.38e-98 gtcA - - S - - - Teichoic acid glycosylation protein
HPKLIDJL_01772 2.01e-305 yfmL - - L - - - DEAD DEAH box helicase
HPKLIDJL_01773 4.06e-243 mocA - - S - - - Oxidoreductase
HPKLIDJL_01774 5.17e-83 - - - S - - - Domain of unknown function (DUF4828)
HPKLIDJL_01775 3.12e-135 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HPKLIDJL_01776 3.18e-206 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HPKLIDJL_01777 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HPKLIDJL_01778 2.58e-180 - - - S - - - NADPH-dependent FMN reductase
HPKLIDJL_01779 1.01e-44 yneR - - S - - - Belongs to the HesB IscA family
HPKLIDJL_01780 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
HPKLIDJL_01781 4.16e-112 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HPKLIDJL_01782 8.96e-136 - - - - - - - -
HPKLIDJL_01783 1.68e-277 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HPKLIDJL_01784 1.14e-129 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HPKLIDJL_01785 5.91e-78 - - - EGP - - - Major Facilitator Superfamily
HPKLIDJL_01786 1.2e-28 - - - EGP - - - Major Facilitator Superfamily
HPKLIDJL_01787 9.43e-13 - - - EGP - - - Major Facilitator Superfamily
HPKLIDJL_01788 4.36e-129 ogt 2.1.1.63 - L ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HPKLIDJL_01789 9.54e-134 - - - S - - - CAAX protease self-immunity
HPKLIDJL_01791 3.51e-154 - - - Q - - - Methyltransferase domain
HPKLIDJL_01792 1.03e-120 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HPKLIDJL_01793 1.28e-67 - - - K - - - 2 iron, 2 sulfur cluster binding
HPKLIDJL_01794 0.0 sufI - - Q - - - Multicopper oxidase
HPKLIDJL_01795 5.51e-116 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
HPKLIDJL_01796 7.61e-95 - 3.5.3.18 - E ko:K01482 - ko00000,ko01000,ko04147 Amidinotransferase
HPKLIDJL_01798 4.35e-247 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HPKLIDJL_01799 2.59e-235 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HPKLIDJL_01800 4.3e-30 - - - D ko:K19158 - ko00000,ko01000,ko02048 mRNA cleavage
HPKLIDJL_01801 7.53e-18 - - - D - - - Antitoxin component of a toxin-antitoxin (TA) module
HPKLIDJL_01802 2.6e-75 - - - L - - - Helix-turn-helix domain
HPKLIDJL_01803 7.45e-196 - - - L ko:K07497 - ko00000 hmm pf00665
HPKLIDJL_01804 1.35e-164 - - - L - - - PFAM transposase, IS4 family protein
HPKLIDJL_01805 2.21e-160 - - - L - - - PFAM transposase, IS4 family protein
HPKLIDJL_01806 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
HPKLIDJL_01807 4.76e-290 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HPKLIDJL_01808 8.28e-292 - - - L - - - MULE transposase domain
HPKLIDJL_01809 1.74e-24 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HPKLIDJL_01810 2.26e-43 - - - L ko:K07483 - ko00000 Transposase
HPKLIDJL_01811 1.8e-217 - - - L ko:K07497 - ko00000 Integrase core domain
HPKLIDJL_01812 1.38e-114 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HPKLIDJL_01813 8.54e-63 - - - L - - - Helix-turn-helix domain
HPKLIDJL_01814 2.21e-114 - - - L ko:K07497 - ko00000 hmm pf00665
HPKLIDJL_01815 2.59e-145 - - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
HPKLIDJL_01816 1.19e-61 - - - D - - - Di-iron-containing protein involved in the repair of iron-sulfur clusters
HPKLIDJL_01817 1.04e-45 copZ - - P - - - Heavy-metal-associated domain
HPKLIDJL_01818 0.0 - 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
HPKLIDJL_01819 3.3e-105 - - - - - - - -
HPKLIDJL_01820 1.73e-218 - - - L - - - Transposase and inactivated derivatives IS30 family
HPKLIDJL_01821 9.78e-67 - - - L - - - Transposase and inactivated derivatives, IS30 family
HPKLIDJL_01822 1.18e-182 - - - L - - - Transposase and inactivated derivatives, IS30 family
HPKLIDJL_01823 7.83e-65 - - - K - - - TRANSCRIPTIONal
HPKLIDJL_01824 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPKLIDJL_01825 3.07e-238 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
HPKLIDJL_01826 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPKLIDJL_01827 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HPKLIDJL_01828 6.72e-63 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPKLIDJL_01829 4.63e-225 camS - - S - - - sex pheromone
HPKLIDJL_01830 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HPKLIDJL_01831 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HPKLIDJL_01832 7.47e-280 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HPKLIDJL_01833 6.46e-131 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HPKLIDJL_01834 2.33e-142 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
HPKLIDJL_01835 1.74e-177 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
HPKLIDJL_01836 3.84e-278 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_01837 1.66e-234 - - - S - - - interspecies interaction between organisms
HPKLIDJL_01838 2.78e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HPKLIDJL_01839 5.57e-104 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HPKLIDJL_01840 6.64e-187 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HPKLIDJL_01841 2.37e-178 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPKLIDJL_01842 1.97e-199 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPKLIDJL_01843 7.14e-192 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPKLIDJL_01844 1.02e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HPKLIDJL_01845 2.01e-216 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPKLIDJL_01846 8.02e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HPKLIDJL_01847 1.32e-76 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HPKLIDJL_01848 6.38e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HPKLIDJL_01849 1.69e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HPKLIDJL_01850 2.16e-156 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HPKLIDJL_01851 5.51e-301 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HPKLIDJL_01852 3.5e-92 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HPKLIDJL_01853 1.2e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HPKLIDJL_01854 3.59e-113 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HPKLIDJL_01855 5.55e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HPKLIDJL_01856 1.02e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HPKLIDJL_01857 7.64e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HPKLIDJL_01858 2.46e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPKLIDJL_01859 1.75e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HPKLIDJL_01860 1.28e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HPKLIDJL_01861 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HPKLIDJL_01862 4.48e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HPKLIDJL_01863 1.35e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HPKLIDJL_01864 2.78e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HPKLIDJL_01865 3.43e-156 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HPKLIDJL_01866 5.3e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HPKLIDJL_01867 1.51e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HPKLIDJL_01868 3.32e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HPKLIDJL_01869 2.76e-60 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HPKLIDJL_01870 1.56e-137 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HPKLIDJL_01871 5.89e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HPKLIDJL_01872 3.14e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HPKLIDJL_01873 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HPKLIDJL_01874 4.15e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HPKLIDJL_01875 3.58e-93 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HPKLIDJL_01876 1.77e-40 pilD 3.4.23.43 - NOU ko:K02236,ko:K02506,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 aspartic-type endopeptidase activity
HPKLIDJL_01877 3.02e-275 - - - - - - - -
HPKLIDJL_01878 2.92e-173 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HPKLIDJL_01879 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPKLIDJL_01880 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPKLIDJL_01881 1.16e-134 - - - K - - - Bacterial regulatory proteins, tetR family
HPKLIDJL_01882 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HPKLIDJL_01883 6.36e-103 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HPKLIDJL_01884 1.37e-247 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HPKLIDJL_01885 8.37e-171 XK27_07210 - - S - - - B3 4 domain
HPKLIDJL_01886 1.49e-154 - - - J - - - 2'-5' RNA ligase superfamily
HPKLIDJL_01888 2.76e-68 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HPKLIDJL_01889 7.14e-191 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HPKLIDJL_01890 1.77e-58 - - - IQ - - - reductase
HPKLIDJL_01891 2.74e-14 fabG1 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HPKLIDJL_01897 4.69e-151 dgk2 - - F - - - deoxynucleoside kinase
HPKLIDJL_01898 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
HPKLIDJL_01900 1.4e-198 - - - I - - - alpha/beta hydrolase fold
HPKLIDJL_01901 3.13e-149 - - - I - - - phosphatase
HPKLIDJL_01902 1.16e-106 - - - S - - - Threonine/Serine exporter, ThrE
HPKLIDJL_01903 3.88e-161 - - - S - - - Putative threonine/serine exporter
HPKLIDJL_01904 5.79e-39 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HPKLIDJL_01905 2.24e-157 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
HPKLIDJL_01906 3.58e-208 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
HPKLIDJL_01907 9.24e-151 - - - S - - - membrane
HPKLIDJL_01908 3.32e-142 - - - S - - - VIT family
HPKLIDJL_01909 7.13e-110 - - - T - - - Belongs to the universal stress protein A family
HPKLIDJL_01910 1.18e-28 elaA - - S ko:K02348 - ko00000 acyltransferase COG2153
HPKLIDJL_01911 2.28e-284 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HPKLIDJL_01912 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPKLIDJL_01913 1.15e-77 - - - - - - - -
HPKLIDJL_01914 3.98e-96 - - - K - - - MerR HTH family regulatory protein
HPKLIDJL_01915 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HPKLIDJL_01916 2.34e-150 - - - S - - - Domain of unknown function (DUF4811)
HPKLIDJL_01917 2.47e-187 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
HPKLIDJL_01918 1.8e-218 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HPKLIDJL_01920 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HPKLIDJL_01921 5.79e-138 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
HPKLIDJL_01922 1.92e-241 - - - I - - - Alpha beta
HPKLIDJL_01923 6.93e-155 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
HPKLIDJL_01924 0.0 - - - S - - - Putative threonine/serine exporter
HPKLIDJL_01925 1.07e-207 mleR2 - - K - - - LysR family transcriptional regulator
HPKLIDJL_01926 9.54e-159 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HPKLIDJL_01927 1.02e-75 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HPKLIDJL_01928 2.25e-270 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HPKLIDJL_01929 6.54e-283 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HPKLIDJL_01930 3.53e-117 - - - S - - - NADPH-dependent FMN reductase
HPKLIDJL_01931 2.02e-233 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
HPKLIDJL_01932 1.54e-289 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
HPKLIDJL_01933 1.12e-98 mleR - - K - - - LysR family
HPKLIDJL_01934 3.11e-73 - 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
HPKLIDJL_01935 4.79e-291 - - - L - - - MULE transposase domain
HPKLIDJL_01936 8.95e-161 - - - S - - - EcsC protein family
HPKLIDJL_01937 1.31e-35 tnp1216 - - L ko:K07498 - ko00000 DDE domain
HPKLIDJL_01939 5.42e-226 - - - L - - - Transposase and inactivated derivatives, IS30 family
HPKLIDJL_01940 8.89e-96 - - - L - - - MULE transposase domain
HPKLIDJL_01941 7.63e-137 - - - L - - - MULE transposase domain
HPKLIDJL_01942 2.6e-75 - - - L - - - Helix-turn-helix domain
HPKLIDJL_01943 2.71e-198 - - - L ko:K07497 - ko00000 hmm pf00665
HPKLIDJL_01944 1.87e-139 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPKLIDJL_01945 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HPKLIDJL_01946 1.37e-248 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
HPKLIDJL_01947 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HPKLIDJL_01948 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
HPKLIDJL_01949 1.71e-211 - - - K - - - LysR substrate binding domain
HPKLIDJL_01950 5.49e-212 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
HPKLIDJL_01951 5.32e-142 - - - - - - - -
HPKLIDJL_01953 0.0 potE - - E - - - Amino Acid
HPKLIDJL_01954 3.77e-217 - - - V - - - Beta-lactamase enzyme family
HPKLIDJL_01955 1.47e-286 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HPKLIDJL_01956 5.21e-126 - - - - - - - -
HPKLIDJL_01957 7.4e-254 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HPKLIDJL_01958 3.77e-139 - - - I - - - PAP2 superfamily
HPKLIDJL_01959 3.11e-71 - - - S - - - MazG-like family
HPKLIDJL_01960 0.0 - - - L - - - Helicase C-terminal domain protein
HPKLIDJL_01961 6.41e-92 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HPKLIDJL_01962 1.09e-122 - - - K - - - transcriptional regulator
HPKLIDJL_01963 1.98e-167 ycnB - - U - - - Belongs to the major facilitator superfamily
HPKLIDJL_01964 2e-304 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_01965 4.21e-105 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_01966 5.4e-62 ycnB - - U - - - Belongs to the major facilitator superfamily
HPKLIDJL_01968 1.28e-313 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HPKLIDJL_01971 8.11e-52 - - - S - - - Cytochrome B5
HPKLIDJL_01972 1.62e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HPKLIDJL_01973 4.09e-272 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HPKLIDJL_01974 1.91e-11 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
HPKLIDJL_01975 5.59e-250 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
HPKLIDJL_01976 7.88e-115 - - - NU - - - mannosyl-glycoprotein
HPKLIDJL_01977 7.04e-87 - - - K - - - Acetyltransferase (GNAT) family
HPKLIDJL_01978 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
HPKLIDJL_01979 4.35e-108 - - - S - - - Psort location Cytoplasmic, score
HPKLIDJL_01980 2.31e-95 - - - K - - - helix_turn_helix, mercury resistance
HPKLIDJL_01981 2.19e-172 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
HPKLIDJL_01982 6.73e-243 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
HPKLIDJL_01983 1.59e-86 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HPKLIDJL_01984 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
HPKLIDJL_01985 2.38e-171 - - - S ko:K07160 - ko00000 LamB/YcsF family
HPKLIDJL_01986 4.26e-272 ycsG - - P - - - Natural resistance-associated macrophage protein
HPKLIDJL_01987 1.79e-266 - - - EGP - - - Major Facilitator
HPKLIDJL_01988 0.0 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
HPKLIDJL_01989 5.57e-70 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HPKLIDJL_01990 2.65e-89 - - - S ko:K07088 - ko00000 Membrane transport protein
HPKLIDJL_01991 6.92e-94 - - - S ko:K07088 - ko00000 Membrane transport protein
HPKLIDJL_01993 2.85e-287 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_01994 3.57e-59 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_01995 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HPKLIDJL_01996 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
HPKLIDJL_01997 2.13e-75 - - - S - - - NADPH-dependent FMN reductase
HPKLIDJL_01998 3.59e-10 - - - S - - - NADPH-dependent FMN reductase
HPKLIDJL_01999 2.16e-201 yneP - - L ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
HPKLIDJL_02000 2.74e-68 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HPKLIDJL_02001 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HPKLIDJL_02002 2.45e-296 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HPKLIDJL_02003 8.4e-302 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPKLIDJL_02004 3.41e-84 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_02005 3.77e-219 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_02006 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HPKLIDJL_02007 4.59e-133 - - - K - - - Transcriptional regulator
HPKLIDJL_02008 6.15e-31 XK27_06785 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HPKLIDJL_02009 7e-218 - - - M ko:K02004 - ko00000,ko00002,ko02000 Membrane
HPKLIDJL_02010 3.17e-74 - - - S - - - FMN_bind
HPKLIDJL_02011 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKLIDJL_02012 8.31e-159 - - - K - - - Bacterial regulatory proteins, tetR family
HPKLIDJL_02013 9.58e-65 - 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Arginase family
HPKLIDJL_02014 4.42e-221 - 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
HPKLIDJL_02015 6.7e-72 - - - K - - - Helix-turn-helix domain
HPKLIDJL_02016 2.77e-134 - - - S - - - Domain of unknown function (DUF4767)
HPKLIDJL_02017 1.87e-156 - - - - - - - -
HPKLIDJL_02019 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
HPKLIDJL_02020 0.0 - 1.7.2.5 - P ko:K04561 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Cytochrome C and Quinol oxidase polypeptide I
HPKLIDJL_02021 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HPKLIDJL_02022 9.55e-146 - - - T - - - Region found in RelA / SpoT proteins
HPKLIDJL_02023 6.69e-101 dltr - - K - - - response regulator
HPKLIDJL_02024 5.13e-165 sptS - - T - - - Histidine kinase
HPKLIDJL_02025 1.61e-223 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HPKLIDJL_02026 4.65e-134 - - - K - - - acetyltransferase
HPKLIDJL_02027 5e-173 - - - IQ - - - dehydrogenase reductase
HPKLIDJL_02028 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HPKLIDJL_02029 2.34e-205 - - - EG - - - EamA-like transporter family
HPKLIDJL_02030 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HPKLIDJL_02031 2.5e-153 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
HPKLIDJL_02032 1.92e-155 pgm3 - - G - - - phosphoglycerate mutase
HPKLIDJL_02033 2.4e-296 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HPKLIDJL_02034 9.22e-268 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HPKLIDJL_02035 3.55e-173 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HPKLIDJL_02036 0.0 - - - E - - - amino acid
HPKLIDJL_02037 1.83e-69 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_02038 9.74e-129 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_02039 1.75e-134 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPKLIDJL_02040 8.23e-178 - 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 UDP-N-acetylglucosamine 2-epimerase
HPKLIDJL_02042 3.44e-309 yhgE - - V ko:K01421 - ko00000 domain protein
HPKLIDJL_02043 1.42e-120 - - - K - - - Transcriptional regulator (TetR family)
HPKLIDJL_02044 1.38e-251 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HPKLIDJL_02045 1.66e-215 - - - - - - - -
HPKLIDJL_02046 4.69e-10 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
HPKLIDJL_02047 7.28e-110 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HPKLIDJL_02048 9.61e-137 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
HPKLIDJL_02049 8.97e-95 - - - F - - - Nudix hydrolase
HPKLIDJL_02050 9.87e-261 yhdG - - E ko:K03294 - ko00000 Amino Acid
HPKLIDJL_02051 2e-304 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_02052 1.03e-105 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_02053 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HPKLIDJL_02054 1.11e-226 - 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HPKLIDJL_02055 3.43e-148 - - - S - - - HAD hydrolase, family IA, variant
HPKLIDJL_02056 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
HPKLIDJL_02057 8.41e-235 - 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
HPKLIDJL_02058 3.77e-217 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
HPKLIDJL_02059 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPKLIDJL_02060 1.64e-108 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
HPKLIDJL_02061 8.3e-141 yciB - - M - - - ErfK YbiS YcfS YnhG
HPKLIDJL_02062 1.64e-262 yngD - - S ko:K07097 - ko00000 DHHA1 domain
HPKLIDJL_02063 0.0 - - - S - - - ABC transporter, ATP-binding protein
HPKLIDJL_02064 8.03e-231 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HPKLIDJL_02065 3.76e-193 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HPKLIDJL_02066 5.36e-170 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKLIDJL_02068 2.17e-286 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
HPKLIDJL_02069 7.48e-298 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
HPKLIDJL_02070 7.93e-217 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HPKLIDJL_02071 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HPKLIDJL_02072 4.17e-236 fruR3 - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
HPKLIDJL_02073 9.89e-207 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
HPKLIDJL_02074 1.72e-213 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPKLIDJL_02075 3.45e-74 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HPKLIDJL_02076 5.82e-182 yceF - - P ko:K05794 - ko00000 membrane
HPKLIDJL_02077 1.12e-212 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HPKLIDJL_02078 3.77e-217 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HPKLIDJL_02079 1.24e-298 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
HPKLIDJL_02080 1.18e-191 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
HPKLIDJL_02081 3.31e-162 pgm3 - - G - - - phosphoglycerate mutase family
HPKLIDJL_02082 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HPKLIDJL_02083 1.3e-110 - - - - - - - -
HPKLIDJL_02084 3.13e-141 flp - - K ko:K21562 - ko00000,ko03000 helix_turn_helix, cAMP Regulatory protein
HPKLIDJL_02085 8.02e-130 dpsB - - P - - - Belongs to the Dps family
HPKLIDJL_02086 6.69e-47 copZ - - P - - - Heavy-metal-associated domain
HPKLIDJL_02087 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
HPKLIDJL_02088 1.51e-235 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HPKLIDJL_02089 3.41e-231 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
HPKLIDJL_02090 4.09e-131 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HPKLIDJL_02091 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HPKLIDJL_02092 8.69e-149 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HPKLIDJL_02093 2.52e-22 - - - - - - - -
HPKLIDJL_02094 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
HPKLIDJL_02095 2.27e-245 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
HPKLIDJL_02096 9.46e-96 - - - O - - - OsmC-like protein
HPKLIDJL_02097 1.46e-237 ybcH - - D ko:K06889 - ko00000 Alpha beta
HPKLIDJL_02098 2.22e-98 - - - K - - - Transcriptional regulator
HPKLIDJL_02099 1.92e-203 - - - - - - - -
HPKLIDJL_02100 4.83e-10 - - - - - - - -
HPKLIDJL_02101 6.25e-78 - - - - - - - -
HPKLIDJL_02102 2.16e-98 uspA3 - - T - - - universal stress protein
HPKLIDJL_02104 6.96e-175 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
HPKLIDJL_02105 2.72e-314 glpT - - G ko:K02445 - ko00000,ko02000 Major Facilitator Superfamily
HPKLIDJL_02106 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HPKLIDJL_02107 6.86e-175 tal 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
HPKLIDJL_02108 3.16e-160 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HPKLIDJL_02109 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HPKLIDJL_02110 3.19e-244 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HPKLIDJL_02111 2.65e-54 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system galactitol-specific IIB component
HPKLIDJL_02112 9.39e-57 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPKLIDJL_02113 8.7e-162 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPKLIDJL_02114 1.94e-289 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HPKLIDJL_02115 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HPKLIDJL_02116 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
HPKLIDJL_02117 8.61e-89 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HPKLIDJL_02118 2.26e-213 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPKLIDJL_02119 4.55e-215 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
HPKLIDJL_02120 9.74e-146 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HPKLIDJL_02121 1.23e-254 - - - S - - - Domain of unknown function (DUF4432)
HPKLIDJL_02122 2.57e-224 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPKLIDJL_02123 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
HPKLIDJL_02124 4.05e-242 - - - K ko:K02525 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HPKLIDJL_02125 0.0 potE - - E - - - Amino Acid
HPKLIDJL_02127 3.37e-291 - - - L - - - MULE transposase domain
HPKLIDJL_02129 3.02e-61 - - - L - - - MULE transposase domain
HPKLIDJL_02130 3.4e-192 - - - L ko:K07482 - ko00000 Helix-turn-helix domain
HPKLIDJL_02131 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HPKLIDJL_02132 1.83e-22 - - - - - - - -
HPKLIDJL_02133 4.76e-131 - - - K - - - Bacterial regulatory proteins, tetR family
HPKLIDJL_02134 4.11e-24 - - - L - - - transposase and inactivated derivatives, IS30 family
HPKLIDJL_02135 1.83e-158 - - - L - - - Transposase and inactivated derivatives, IS30 family
HPKLIDJL_02136 1.71e-122 tnpR1 - - L - - - Resolvase, N terminal domain
HPKLIDJL_02137 8.28e-292 - - - L - - - MULE transposase domain
HPKLIDJL_02138 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HPKLIDJL_02139 4.15e-189 - - - S - - - haloacid dehalogenase-like hydrolase
HPKLIDJL_02140 3.81e-169 gntR - - K - - - UbiC transcription regulator-associated domain protein
HPKLIDJL_02141 4.23e-115 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HPKLIDJL_02142 3.78e-167 - - - - - - - -
HPKLIDJL_02143 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HPKLIDJL_02144 8.78e-198 - - - G - - - Xylose isomerase domain protein TIM barrel
HPKLIDJL_02145 9.84e-112 - - - K - - - Domain of unknown function (DUF1836)
HPKLIDJL_02146 1.14e-114 - - - GM - - - epimerase
HPKLIDJL_02147 0.0 yhdP - - S - - - Transporter associated domain
HPKLIDJL_02148 3.05e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
HPKLIDJL_02149 1.81e-98 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
HPKLIDJL_02150 3.6e-266 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
HPKLIDJL_02151 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HPKLIDJL_02152 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HPKLIDJL_02153 3.03e-106 usp5 - - T - - - universal stress protein
HPKLIDJL_02154 4.36e-103 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
HPKLIDJL_02155 2.31e-181 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HPKLIDJL_02156 4.82e-229 - - - K ko:K02525 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HPKLIDJL_02157 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HPKLIDJL_02158 1.29e-298 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HPKLIDJL_02159 2.51e-160 - - - S - - - Membrane
HPKLIDJL_02160 1.92e-51 - - - L ko:K07483 - ko00000 Transposase
HPKLIDJL_02161 4.33e-186 - - - L - - - 4.5 Transposon and IS
HPKLIDJL_02162 0.0 dld 1.1.5.12 - C ko:K03777 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 D-lactate dehydrogenase, membrane binding
HPKLIDJL_02163 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HPKLIDJL_02166 3.53e-28 - - - L ko:K07497 - ko00000 hmm pf00665
HPKLIDJL_02167 5.92e-157 ribB 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HPKLIDJL_02169 1.94e-289 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HPKLIDJL_02170 3.38e-241 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
HPKLIDJL_02171 2.86e-244 - - - L - - - Transposase and inactivated derivatives, IS30 family
HPKLIDJL_02172 1.49e-120 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HPKLIDJL_02173 9.27e-81 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HPKLIDJL_02174 8.28e-292 - - - L - - - MULE transposase domain
HPKLIDJL_02175 1.25e-109 - - - P - - - Cation efflux family
HPKLIDJL_02176 1.89e-65 tnpR1 - - L - - - Resolvase, N terminal domain
HPKLIDJL_02178 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HPKLIDJL_02179 7.39e-98 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Transcriptional regulator
HPKLIDJL_02180 4.76e-290 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HPKLIDJL_02181 7.93e-47 - - - Q - - - ubiE/COQ5 methyltransferase family
HPKLIDJL_02182 3.11e-218 - - - L ko:K07497 - ko00000 Integrase core domain
HPKLIDJL_02183 2.48e-62 - - - L ko:K07483 - ko00000 Transposase
HPKLIDJL_02184 1.46e-43 crtM 2.5.1.32, 2.5.1.96, 2.5.1.99 - I ko:K02291,ko:K10208 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
HPKLIDJL_02185 2.42e-37 - - - L - - - Helix-turn-helix domain
HPKLIDJL_02186 1.63e-199 - - - L ko:K07497 - ko00000 hmm pf00665
HPKLIDJL_02187 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HPKLIDJL_02188 0.0 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HPKLIDJL_02189 3.03e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HPKLIDJL_02190 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HPKLIDJL_02191 2.97e-284 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HPKLIDJL_02192 6.63e-232 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
HPKLIDJL_02193 5.85e-186 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HPKLIDJL_02194 2.44e-125 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HPKLIDJL_02195 1.21e-48 - - - - - - - -
HPKLIDJL_02196 2.05e-174 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HPKLIDJL_02197 1.81e-156 - - - U ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HPKLIDJL_02198 1.09e-180 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HPKLIDJL_02199 9.08e-71 - - - - - - - -
HPKLIDJL_02200 4.93e-216 - 1.1.1.399, 1.1.1.95 - CH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPKLIDJL_02201 2.57e-104 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HPKLIDJL_02202 8.79e-188 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HPKLIDJL_02203 2.01e-119 ymdB - - S - - - Macro domain protein
HPKLIDJL_02204 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HPKLIDJL_02205 4.26e-291 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HPKLIDJL_02206 8.5e-61 - - - - - - - -
HPKLIDJL_02207 3.18e-273 - - - S - - - Putative metallopeptidase domain
HPKLIDJL_02208 3.31e-262 - - - S - - - associated with various cellular activities
HPKLIDJL_02209 2e-150 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HPKLIDJL_02210 1.42e-85 yeaO - - S - - - Protein of unknown function, DUF488
HPKLIDJL_02212 2.32e-161 yrkL - - S - - - Flavodoxin-like fold
HPKLIDJL_02213 8.76e-73 - - - - - - - -
HPKLIDJL_02214 3.04e-140 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HPKLIDJL_02215 6.55e-126 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HPKLIDJL_02216 2.79e-137 - - - - - - - -
HPKLIDJL_02217 1.11e-35 - - - - - - - -
HPKLIDJL_02218 5.8e-216 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
HPKLIDJL_02219 4.4e-313 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HPKLIDJL_02220 3.55e-61 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
HPKLIDJL_02221 7.5e-100 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HPKLIDJL_02222 2.9e-158 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HPKLIDJL_02223 1.65e-208 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HPKLIDJL_02224 2.63e-137 - - - K - - - Bacterial regulatory proteins, tetR family
HPKLIDJL_02225 1.58e-240 - - - E - - - Zinc-binding dehydrogenase
HPKLIDJL_02226 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HPKLIDJL_02227 1.71e-52 - - - - - - - -
HPKLIDJL_02228 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HPKLIDJL_02229 1.01e-111 - - - L - - - nuclease
HPKLIDJL_02230 5.11e-208 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HPKLIDJL_02231 2.37e-291 - - - L - - - MULE transposase domain
HPKLIDJL_02232 4.85e-195 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_02233 6.82e-73 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_02235 1.16e-146 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HPKLIDJL_02236 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPKLIDJL_02237 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPKLIDJL_02238 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HPKLIDJL_02239 6.18e-284 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
HPKLIDJL_02242 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HPKLIDJL_02243 2.52e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HPKLIDJL_02244 1.03e-105 - - - L ko:K07491 - ko00000 Transposase IS200 like
HPKLIDJL_02245 8.16e-304 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HPKLIDJL_02246 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HPKLIDJL_02247 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HPKLIDJL_02248 1.83e-198 jag - - S ko:K06346 - ko00000 R3H domain protein
HPKLIDJL_02249 4.99e-187 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HPKLIDJL_02250 2.64e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HPKLIDJL_02251 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)