ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
LEOBILOC_00002 3.34e-67 yfhH - - S - - - Protein of unknown function (DUF1811)
LEOBILOC_00003 1.56e-187 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
LEOBILOC_00004 1.73e-07 - - - S - - - YfhE-like protein
LEOBILOC_00005 2.42e-33 yfhD - - S - - - YfhD-like protein
LEOBILOC_00006 3.41e-187 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LEOBILOC_00008 4.6e-291 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LEOBILOC_00009 0.0 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
LEOBILOC_00010 8.37e-234 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LEOBILOC_00011 1.08e-140 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase
LEOBILOC_00012 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LEOBILOC_00013 2.23e-262 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
LEOBILOC_00014 7.71e-157 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LEOBILOC_00015 2.24e-239 bacG - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LEOBILOC_00017 5.35e-12 - - - - - - - -
LEOBILOC_00018 1.06e-112 - - - S - - - Stage II sporulation protein M
LEOBILOC_00019 6.86e-163 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LEOBILOC_00021 6.02e-62 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
LEOBILOC_00023 0.0 - - - - - - - -
LEOBILOC_00024 6.79e-206 - - - L - - - Transposase, Mutator family
LEOBILOC_00025 1.82e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LEOBILOC_00026 7.07e-44 yodI - - - - - - -
LEOBILOC_00027 7.51e-194 yjaZ - - O - - - Zn-dependent protease
LEOBILOC_00028 3.84e-171 yodH - - Q - - - Methyltransferase
LEOBILOC_00029 1.45e-148 - - - S - - - PD-(D/E)XK nuclease family transposase
LEOBILOC_00030 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
LEOBILOC_00031 2.6e-180 - - - S - - - HIRAN
LEOBILOC_00032 9.39e-143 sorD 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
LEOBILOC_00033 3.49e-234 - - - K ko:K03491 - ko00000,ko03000 transcriptional regulator, MtlR
LEOBILOC_00034 6.78e-58 srlM1 - - K - - - Glucitol operon activator protein (GutM)
LEOBILOC_00035 4.83e-104 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
LEOBILOC_00036 1.02e-203 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol sorbitol-specific transporter subunit IIB
LEOBILOC_00037 3.1e-50 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
LEOBILOC_00038 4.73e-100 - - - H ko:K08314 - ko00000,ko01000 COG0176 Transaldolase
LEOBILOC_00039 0.0 - - - L - - - Transposase, IS4 family protein
LEOBILOC_00040 1.29e-40 - - - K - - - Cro/C1-type HTH DNA-binding domain
LEOBILOC_00041 9.34e-128 - - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein domain
LEOBILOC_00042 1.96e-68 fucU 5.1.3.29 - G ko:K02431 - ko00000,ko01000 Belongs to the RbsD FucU family
LEOBILOC_00043 7.05e-284 mglA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
LEOBILOC_00044 1.09e-156 - - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LEOBILOC_00045 9.04e-154 - - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
LEOBILOC_00046 9.17e-260 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
LEOBILOC_00047 0.0 fucI 5.3.1.25, 5.3.1.3 - G ko:K01818 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Converts the aldose L-fucose into the corresponding ketose L-fuculose
LEOBILOC_00048 4.72e-132 - 4.1.2.17 - G ko:K01628 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Aldolase
LEOBILOC_00049 8.86e-300 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
LEOBILOC_00050 1.6e-102 - - - S - - - Uncharacterised protein family UPF0047
LEOBILOC_00051 9.47e-125 - 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 triosephosphate isomerase
LEOBILOC_00052 6.71e-101 - - - G - - - aldolase
LEOBILOC_00053 3.68e-41 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LEOBILOC_00054 2.58e-237 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
LEOBILOC_00055 4.93e-42 - 2.7.1.200 - GT ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LEOBILOC_00057 2.25e-148 - - - K ko:K02538 - ko00000,ko03000 PRD domain
LEOBILOC_00058 5.77e-214 - - - S - - - Nuclease-related domain
LEOBILOC_00059 4.9e-263 - - - L - - - Transposase IS4 family protein
LEOBILOC_00060 1.48e-213 - - - K - - - AraC-like ligand binding domain
LEOBILOC_00061 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
LEOBILOC_00062 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
LEOBILOC_00063 1.85e-203 rhaD 4.1.2.19 - G ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
LEOBILOC_00064 1.63e-43 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 - C ko:K00048,ko:K13954,ko:K17067 ko00010,ko00071,ko00350,ko00625,ko00626,ko00630,ko00640,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00630,map00640,map00680,map01100,map01110,map01120,map01130,map01200,map01220 ko00000,ko00001,ko01000 hydroxyacid-oxoacid transhydrogenase activity
LEOBILOC_00065 8.38e-98 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
LEOBILOC_00066 8.92e-136 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LEOBILOC_00067 6.12e-312 - - - EGP - - - Major facilitator superfamily
LEOBILOC_00068 0.0 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
LEOBILOC_00069 1.27e-128 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
LEOBILOC_00070 1.39e-134 - - - K - - - Acetyltransferase (GNAT) domain
LEOBILOC_00071 1.89e-243 XK27_12525 - - S - - - AI-2E family transporter
LEOBILOC_00072 1.41e-206 - - - S - - - hydrolases of the HAD superfamily
LEOBILOC_00073 3.48e-155 - - - L - - - Transposase, IS4 family protein
LEOBILOC_00074 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LEOBILOC_00075 1.23e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LEOBILOC_00076 2.3e-143 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LEOBILOC_00077 8.45e-300 deoA 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
LEOBILOC_00078 2.88e-292 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
LEOBILOC_00079 4.09e-222 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LEOBILOC_00080 1.68e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
LEOBILOC_00081 6.29e-272 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LEOBILOC_00082 1.67e-290 pbuO_1 - - S ko:K06901 - ko00000,ko02000 permease
LEOBILOC_00083 3.17e-150 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LEOBILOC_00084 2.83e-213 - - - S - - - Protein of unknown function (DUF979)
LEOBILOC_00085 9.65e-152 - - - S - - - Protein of unknown function (DUF969)
LEOBILOC_00086 9.67e-174 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
LEOBILOC_00087 5.86e-230 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
LEOBILOC_00088 9.05e-169 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
LEOBILOC_00089 2.11e-271 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LEOBILOC_00090 6.48e-104 ymaD - - O - - - redox protein, regulator of disulfide bond formation
LEOBILOC_00091 1.55e-167 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LEOBILOC_00092 4.82e-147 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LEOBILOC_00093 2.89e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
LEOBILOC_00094 3.53e-275 hipO3 - - S ko:K21613 - ko00000,ko01000,ko01002 amidohydrolase
LEOBILOC_00095 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
LEOBILOC_00096 2.14e-290 - - - M - - - FFAT motif binding
LEOBILOC_00097 6.6e-124 - - - I - - - Domain of unknown function (DUF4430)
LEOBILOC_00098 3.34e-120 - - - S ko:K16927 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
LEOBILOC_00099 5.3e-144 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
LEOBILOC_00100 1.16e-145 - - - M - - - Methyltransferase
LEOBILOC_00101 1.64e-263 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
LEOBILOC_00102 1.47e-50 - - - S - - - Protein of unknown function DUF86
LEOBILOC_00103 3.35e-72 - - - S - - - Nucleotidyltransferase domain
LEOBILOC_00104 4.95e-246 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
LEOBILOC_00106 8.61e-104 - 1.1.1.53 - IQ ko:K00038 ko00140,ko01100,map00140,map01100 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEOBILOC_00107 2.83e-52 - - - S - - - Protein of unknown function (DUF2750)
LEOBILOC_00110 2.86e-140 - - - EGP - - - Major Facilitator
LEOBILOC_00111 6.61e-182 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
LEOBILOC_00112 1.61e-187 - - - S - - - Protein of unknown function
LEOBILOC_00113 3.19e-182 - - - S - - - Protein of unknown function (DUF2961)
LEOBILOC_00114 1.45e-83 - - - - - - - -
LEOBILOC_00115 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
LEOBILOC_00116 6.16e-131 - - - K - - - Iron dependent repressor, N-terminal DNA binding domain
LEOBILOC_00117 2.73e-55 - - - - - - - -
LEOBILOC_00118 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEOBILOC_00119 1.33e-196 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LEOBILOC_00120 1.57e-187 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
LEOBILOC_00121 1.55e-38 yfjT - - - - - - -
LEOBILOC_00122 3.16e-188 yfkD - - S - - - YfkD-like protein
LEOBILOC_00123 1.01e-231 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
LEOBILOC_00124 5.28e-282 yfkF - - EGP - - - Major facilitator superfamily
LEOBILOC_00125 5.39e-188 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
LEOBILOC_00126 6.01e-45 yfkK - - S - - - Belongs to the UPF0435 family
LEOBILOC_00127 7.76e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
LEOBILOC_00128 2.24e-117 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
LEOBILOC_00129 2.51e-174 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
LEOBILOC_00130 2.09e-174 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
LEOBILOC_00131 7.7e-75 ydhN1 - - S - - - Domain of unknown function (DUF1992)
LEOBILOC_00132 4.69e-79 yeaO - - S - - - Protein of unknown function, DUF488
LEOBILOC_00133 1.38e-291 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LEOBILOC_00134 4.15e-184 yteA - - T - - - COG1734 DnaK suppressor protein
LEOBILOC_00135 1.63e-110 ykhA - - I - - - Acyl-CoA hydrolase
LEOBILOC_00136 6.62e-233 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
LEOBILOC_00137 1.15e-260 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
LEOBILOC_00138 2.1e-117 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
LEOBILOC_00139 1.73e-271 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LEOBILOC_00140 1.6e-217 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
LEOBILOC_00141 1.34e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LEOBILOC_00142 1.15e-151 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
LEOBILOC_00143 8.61e-132 - 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
LEOBILOC_00145 5.25e-165 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LEOBILOC_00147 0.0 - - - K - - - helix_turn_helix, Lux Regulon
LEOBILOC_00148 6.61e-128 - - - - - - - -
LEOBILOC_00149 2.92e-89 - - - S - - - response to pH
LEOBILOC_00150 7.26e-139 - - - - - - - -
LEOBILOC_00151 2.61e-207 ypuA - - S - - - Secreted protein
LEOBILOC_00152 1.77e-197 gntR - - K - - - RpiR family transcriptional regulator
LEOBILOC_00153 1.57e-281 - 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LEOBILOC_00154 5.23e-295 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEOBILOC_00155 9.17e-150 gpmB - - G ko:K15640 - ko00000 Histidine phosphatase superfamily (branch 1)
LEOBILOC_00156 5.91e-93 - - - K - - - Transcriptional
LEOBILOC_00157 7.56e-52 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LEOBILOC_00158 4.43e-214 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LEOBILOC_00159 3.35e-127 cas4 3.1.12.1 - L ko:K07464 - ko00000,ko01000,ko02048 RecB family exonuclease
LEOBILOC_00160 7.32e-173 csd2 - - L ko:K19115,ko:K19118 - ko00000,ko02048 CRISPR-associated protein
LEOBILOC_00161 0.0 csd1 - - M ko:K19117 - ko00000,ko02048 CRISPR-associated protein (Cas_Csd1)
LEOBILOC_00162 1.29e-145 cas5 - - S ko:K19119 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas5)
LEOBILOC_00163 0.0 - - - L ko:K07012 - ko00000,ko01000,ko02048 Metal dependent phosphohydrolases with conserved 'HD' motif.
LEOBILOC_00164 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LEOBILOC_00165 2.15e-193 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEOBILOC_00166 8.01e-231 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEOBILOC_00167 2.87e-247 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LEOBILOC_00168 1.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LEOBILOC_00169 8.61e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LEOBILOC_00170 3.43e-156 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LEOBILOC_00171 1.58e-305 coiA - - S ko:K06198 - ko00000 Competence protein
LEOBILOC_00172 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
LEOBILOC_00173 8.6e-118 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
LEOBILOC_00174 3.18e-181 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LEOBILOC_00175 1.98e-212 yocS - - S ko:K03453 - ko00000 -transporter
LEOBILOC_00176 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
LEOBILOC_00177 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
LEOBILOC_00178 6.34e-197 yloC - - S - - - stress-induced protein
LEOBILOC_00179 2.14e-59 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
LEOBILOC_00180 2.24e-140 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
LEOBILOC_00181 4e-40 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LEOBILOC_00182 2.01e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LEOBILOC_00183 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LEOBILOC_00184 4.09e-106 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LEOBILOC_00185 4.64e-228 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LEOBILOC_00186 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LEOBILOC_00187 2.23e-181 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
LEOBILOC_00188 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
LEOBILOC_00189 1.47e-213 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LEOBILOC_00190 6.41e-155 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
LEOBILOC_00191 5.94e-161 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
LEOBILOC_00192 1.22e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
LEOBILOC_00193 3.65e-78 yloU - - S - - - protein conserved in bacteria
LEOBILOC_00194 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
LEOBILOC_00195 8.37e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
LEOBILOC_00196 4.47e-199 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
LEOBILOC_00197 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LEOBILOC_00198 2.53e-127 fapR - - Q - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
LEOBILOC_00199 3.74e-265 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LEOBILOC_00200 2.06e-208 fabD 2.3.1.39 - I ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 malonyl CoA-acyl carrier protein transacylase
LEOBILOC_00201 1.04e-164 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
LEOBILOC_00202 1.64e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LEOBILOC_00203 2.2e-170 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LEOBILOC_00204 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
LEOBILOC_00205 2.69e-230 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LEOBILOC_00206 4.33e-69 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LEOBILOC_00207 1.81e-309 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LEOBILOC_00208 5.58e-59 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
LEOBILOC_00209 1.76e-47 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
LEOBILOC_00210 1.68e-81 - - - S - - - YlqD protein
LEOBILOC_00211 4.35e-120 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LEOBILOC_00212 1.15e-180 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
LEOBILOC_00213 6.22e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LEOBILOC_00214 9.01e-132 sipS 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LEOBILOC_00215 2.33e-202 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LEOBILOC_00216 2.21e-179 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEOBILOC_00217 1.69e-295 - - - D - - - nuclear chromosome segregation
LEOBILOC_00218 3.12e-61 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
LEOBILOC_00219 1.54e-270 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
LEOBILOC_00220 6.5e-215 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LEOBILOC_00221 5.55e-212 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
LEOBILOC_00222 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LEOBILOC_00224 4.77e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
LEOBILOC_00225 1.61e-119 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LEOBILOC_00226 5.03e-299 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LEOBILOC_00227 1.32e-173 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LEOBILOC_00228 2.21e-81 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
LEOBILOC_00229 1.41e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
LEOBILOC_00230 2.29e-55 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body complex protein FliE
LEOBILOC_00231 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
LEOBILOC_00232 8.36e-263 comM - - O ko:K07391 - ko00000 Mg chelatase subunit ChlI
LEOBILOC_00233 1.69e-197 - - - S - - - transposase or invertase
LEOBILOC_00234 3.69e-30 - - - - - - - -
LEOBILOC_00235 2.49e-256 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
LEOBILOC_00236 1.81e-316 xylT - - U ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LEOBILOC_00237 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
LEOBILOC_00238 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
LEOBILOC_00239 9.1e-281 xylR - - GK - - - ROK family
LEOBILOC_00240 5.09e-263 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LEOBILOC_00241 2.24e-202 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
LEOBILOC_00242 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
LEOBILOC_00243 8.89e-269 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LEOBILOC_00244 1.39e-124 - - - S - - - NYN domain
LEOBILOC_00245 1.06e-185 fnt - - P ko:K21993 - ko00000,ko02000 Formate nitrite
LEOBILOC_00246 0.0 - - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
LEOBILOC_00247 2.27e-184 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters
LEOBILOC_00248 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LEOBILOC_00249 5.36e-120 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
LEOBILOC_00250 8.2e-210 XK27_10120 - - S - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
LEOBILOC_00251 3.15e-159 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LEOBILOC_00252 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
LEOBILOC_00253 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEOBILOC_00254 9.41e-278 adhB 1.1.1.1, 1.1.1.202 - C ko:K00001,ko:K00086 ko00010,ko00071,ko00350,ko00561,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00561,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
LEOBILOC_00255 0.0 - - - KT - - - Transcriptional regulator
LEOBILOC_00256 0.0 - - - G - - - Domain of unknown function (DUF5110)
LEOBILOC_00257 0.0 - - - S - - - Predicted membrane protein (DUF2339)
LEOBILOC_00258 1.79e-291 - - - I - - - Acyl-CoA dehydrogenase, N-terminal domain
LEOBILOC_00259 0.0 - 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
LEOBILOC_00260 7.32e-248 - - - S - - - Metallo-beta-lactamase superfamily
LEOBILOC_00261 5.4e-176 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LEOBILOC_00262 1.54e-172 phnE - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LEOBILOC_00263 1.05e-183 ptxC - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LEOBILOC_00264 6.32e-225 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
LEOBILOC_00265 0.0 yfkN_2 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LEOBILOC_00266 5.3e-264 ysdC - - G - - - COG1363 Cellulase M and related proteins
LEOBILOC_00268 1.05e-47 - - - - - - - -
LEOBILOC_00269 9.29e-185 - - - T - - - ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LEOBILOC_00270 4.27e-24 - - - - - - - -
LEOBILOC_00271 1.02e-20 - - - - - - - -
LEOBILOC_00272 2.32e-69 - - - S - - - Domain of unknown function (DUF5085)
LEOBILOC_00273 1.07e-188 yjbA - - S - - - Belongs to the UPF0736 family
LEOBILOC_00274 7.49e-236 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
LEOBILOC_00275 6.02e-62 - - - S - - - Domain of unknown function (DUF3899)
LEOBILOC_00276 1.45e-187 lppC - - M - - - 5'-nucleotidase, lipoprotein e(P4)
LEOBILOC_00279 1e-271 ydbM - - I - - - acyl-CoA dehydrogenase
LEOBILOC_00280 4.55e-23 - - - - - - - -
LEOBILOC_00281 4.01e-281 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LEOBILOC_00282 6.74e-244 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LEOBILOC_00283 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
LEOBILOC_00284 2.71e-262 mro 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Converts alpha-aldose to the beta-anomer
LEOBILOC_00285 3.05e-234 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LEOBILOC_00286 1.15e-43 ydjO - - S - - - Cold-inducible protein YdjO
LEOBILOC_00287 9.05e-22 - - - - - - - -
LEOBILOC_00289 1.85e-207 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
LEOBILOC_00290 1.27e-90 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEOBILOC_00292 6.45e-243 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LEOBILOC_00293 7.11e-224 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LEOBILOC_00295 0.0 bmr3_1 - - P ko:K18935 - ko00000,ko02000 Major facilitator superfamily
LEOBILOC_00296 1.48e-268 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
LEOBILOC_00297 1.69e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LEOBILOC_00298 5e-162 yvoA_2 - - K ko:K03710 - ko00000,ko03000 transcriptional
LEOBILOC_00299 3.01e-251 cwlS - CBM50 M ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LEOBILOC_00300 0.0 - - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
LEOBILOC_00301 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
LEOBILOC_00302 1.36e-225 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
LEOBILOC_00303 4.87e-148 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
LEOBILOC_00304 5.46e-260 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
LEOBILOC_00305 2.8e-159 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEOBILOC_00306 0.0 yfnA - - E ko:K03294 - ko00000 amino acid
LEOBILOC_00307 3.3e-198 degV - - S - - - protein conserved in bacteria
LEOBILOC_00309 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LEOBILOC_00310 1.63e-171 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
LEOBILOC_00311 2.2e-91 yvyF - - S - - - flagellar protein
LEOBILOC_00312 1.24e-52 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
LEOBILOC_00313 1.23e-100 yvyG - - NOU - - - FlgN protein
LEOBILOC_00314 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
LEOBILOC_00315 1.7e-204 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
LEOBILOC_00316 9.57e-106 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LEOBILOC_00317 3.42e-45 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LEOBILOC_00318 1.96e-31 - - - S - - - Nucleotidyltransferase domain
LEOBILOC_00319 1.18e-123 - - - U - - - SEC-C motif
LEOBILOC_00320 1.74e-235 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LEOBILOC_00322 1.6e-216 - - - E - - - COG1113 Gamma-aminobutyrate permease and related permeases
LEOBILOC_00323 0.0 - - - O - - - AAA domain
LEOBILOC_00325 5.12e-137 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
LEOBILOC_00327 5.15e-79 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
LEOBILOC_00328 1.16e-289 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LEOBILOC_00329 1.94e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
LEOBILOC_00330 8.14e-75 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
LEOBILOC_00331 8.95e-127 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LEOBILOC_00332 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
LEOBILOC_00333 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LEOBILOC_00334 1.28e-230 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LEOBILOC_00335 4.34e-202 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LEOBILOC_00336 8.82e-68 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
LEOBILOC_00338 7.33e-177 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
LEOBILOC_00339 2.14e-201 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LEOBILOC_00340 1.19e-181 - - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 peptidase
LEOBILOC_00341 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LEOBILOC_00342 1.23e-313 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 O-acetylhomoserine
LEOBILOC_00343 5.45e-232 - 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
LEOBILOC_00344 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
LEOBILOC_00345 9.26e-290 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LEOBILOC_00346 1.25e-211 fatD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEOBILOC_00347 6.17e-212 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEOBILOC_00348 1.61e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LEOBILOC_00349 5.02e-228 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
LEOBILOC_00350 6.09e-57 fdxA - - C - - - 4Fe-4S binding domain
LEOBILOC_00351 4.18e-61 - - - S - - - Family of unknown function (DUF5316)
LEOBILOC_00352 2.13e-160 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEOBILOC_00353 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
LEOBILOC_00355 0.0 hemG 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LEOBILOC_00356 7.52e-207 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
LEOBILOC_00357 5.24e-209 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
LEOBILOC_00358 1.06e-201 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
LEOBILOC_00359 1.84e-198 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LEOBILOC_00360 2.06e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LEOBILOC_00362 7.07e-222 - - - M - - - Glycosyltransferase like family 2
LEOBILOC_00363 0.0 - - - - - - - -
LEOBILOC_00364 1.39e-76 - - - P - - - EamA-like transporter family
LEOBILOC_00365 3.15e-67 - - - S ko:K12962 ko01503,map01503 ko00000,ko00001,ko00002,ko01005,ko02000 EamA-like transporter family
LEOBILOC_00366 1.06e-152 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
LEOBILOC_00367 4.55e-45 csbA - - S - - - protein conserved in bacteria
LEOBILOC_00369 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LEOBILOC_00370 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LEOBILOC_00371 7.34e-95 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
LEOBILOC_00372 8.19e-287 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LEOBILOC_00373 9.92e-184 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
LEOBILOC_00374 1.14e-200 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LEOBILOC_00375 7.11e-273 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LEOBILOC_00376 0.0 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LEOBILOC_00377 1.44e-186 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
LEOBILOC_00378 1.17e-290 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LEOBILOC_00379 4.37e-224 yvlB - - S - - - Putative adhesin
LEOBILOC_00380 2.84e-61 yvlD - - S ko:K08972 - ko00000 Membrane
LEOBILOC_00381 1.74e-223 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LEOBILOC_00382 3.87e-197 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LEOBILOC_00383 1.2e-155 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
LEOBILOC_00384 1.25e-114 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
LEOBILOC_00385 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
LEOBILOC_00386 2.68e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LEOBILOC_00387 1.35e-111 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Nudix hydrolase
LEOBILOC_00388 8.23e-216 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
LEOBILOC_00389 1.19e-230 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
LEOBILOC_00390 1.67e-221 whiA - - K ko:K09762 - ko00000 May be required for sporulation
LEOBILOC_00391 6.85e-55 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
LEOBILOC_00392 1.16e-133 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LEOBILOC_00394 1.63e-202 - - - S - - - transposase or invertase
LEOBILOC_00395 2.16e-22 - - - S - - - transposase or invertase
LEOBILOC_00396 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LEOBILOC_00397 3.3e-39 B4168_3115 - - S ko:K06419 - ko00000 spore protein
LEOBILOC_00398 1.92e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LEOBILOC_00399 1.11e-208 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
LEOBILOC_00400 2.87e-290 - - - HJ - - - COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)
LEOBILOC_00401 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
LEOBILOC_00402 1.48e-271 yheC - - HJ - - - YheC/D like ATP-grasp
LEOBILOC_00403 0.0 - - - HJ - - - YheC/D like ATP-grasp
LEOBILOC_00404 2.35e-266 yheB - - S - - - Belongs to the UPF0754 family
LEOBILOC_00405 1.3e-71 yheA - - S - - - Belongs to the UPF0342 family
LEOBILOC_00406 2.53e-206 yhaX - - S - - - hydrolases of the HAD superfamily
LEOBILOC_00407 9.33e-179 yhaR - - I - - - enoyl-CoA hydratase
LEOBILOC_00408 7.99e-37 - - - S - - - YhzD-like protein
LEOBILOC_00409 1.51e-163 - - - P - - - Integral membrane protein TerC family
LEOBILOC_00411 1.5e-204 ycgR - - S ko:K07089 - ko00000 permeases
LEOBILOC_00412 9.57e-209 ycgQ - - S ko:K08986 - ko00000 membrane
LEOBILOC_00413 1.64e-304 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
LEOBILOC_00414 0.0 yhaN - - L - - - AAA domain
LEOBILOC_00415 7.73e-230 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
LEOBILOC_00416 2.41e-37 yhaL - - S - - - Sporulation protein YhaL
LEOBILOC_00417 5.03e-198 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LEOBILOC_00418 1.19e-71 yhaI - - S - - - Protein of unknown function (DUF1878)
LEOBILOC_00419 5.83e-135 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
LEOBILOC_00420 9.73e-47 yhaH - - S - - - YtxH-like protein
LEOBILOC_00421 2.39e-109 trpP - - S - - - Tryptophan transporter TrpP
LEOBILOC_00422 2.73e-97 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LEOBILOC_00423 3.54e-177 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
LEOBILOC_00424 2.23e-279 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LEOBILOC_00425 1.07e-285 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LEOBILOC_00426 1.54e-306 yhfA - - C - - - membrane
LEOBILOC_00427 7.85e-122 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
LEOBILOC_00428 1.14e-252 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LEOBILOC_00429 2.07e-235 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
LEOBILOC_00430 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LEOBILOC_00431 4.41e-131 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
LEOBILOC_00432 9.27e-261 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
LEOBILOC_00433 3.54e-212 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
LEOBILOC_00434 7.31e-169 - - - K - - - DeoR C terminal sensor domain
LEOBILOC_00435 4.73e-15 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
LEOBILOC_00436 9e-94 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
LEOBILOC_00437 8.67e-210 - - - EG - - - EamA-like transporter family
LEOBILOC_00438 4.45e-162 aldA 1.2.1.21, 1.2.1.22 - C ko:K07248 ko00620,ko00630,ko01120,map00620,map00630,map01120 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEOBILOC_00439 2.68e-135 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
LEOBILOC_00440 2.58e-85 ytkA - - S - - - YtkA-like
LEOBILOC_00441 1.07e-30 yhfH - - S - - - YhfH-like protein
LEOBILOC_00442 4.71e-238 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
LEOBILOC_00443 0.0 lcfB_2 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 Activates fatty acids by binding to coenzyme A
LEOBILOC_00444 1.31e-153 ygaZ - - E - - - AzlC protein
LEOBILOC_00445 3.18e-56 - - - S - - - branched-chain amino acid
LEOBILOC_00446 2.52e-301 yhfN - - O - - - Peptidase M48
LEOBILOC_00448 1.51e-126 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
LEOBILOC_00449 4.3e-185 - - - S - - - Mitochondrial biogenesis AIM24
LEOBILOC_00451 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
LEOBILOC_00452 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
LEOBILOC_00453 6.43e-41 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
LEOBILOC_00454 6.52e-93 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
LEOBILOC_00455 2.75e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
LEOBILOC_00456 2.32e-144 gerPC - - S ko:K06301 - ko00000 Spore germination protein
LEOBILOC_00457 5.22e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
LEOBILOC_00458 7.25e-286 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
LEOBILOC_00459 1.21e-208 yisK 3.7.1.5 - Q ko:K16164 ko00350,ko01100,ko01120,map00350,map01100,map01120 ko00000,ko00001,ko01000 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
LEOBILOC_00460 1.12e-78 yisL - - S - - - UPF0344 protein
LEOBILOC_00461 2.58e-132 yisN - - S - - - Protein of unknown function (DUF2777)
LEOBILOC_00462 6.67e-203 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEOBILOC_00463 1.8e-08 - - - - - - - -
LEOBILOC_00464 2.09e-208 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
LEOBILOC_00465 2.36e-96 yjbI - - S ko:K06886 - ko00000 COG2346 Truncated hemoglobins
LEOBILOC_00466 5.29e-155 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LEOBILOC_00467 9.61e-137 yjbK - - S - - - protein conserved in bacteria
LEOBILOC_00468 1.63e-82 yjbL - - S - - - Belongs to the UPF0738 family
LEOBILOC_00469 2.41e-158 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
LEOBILOC_00470 4.53e-197 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LEOBILOC_00471 8.83e-208 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LEOBILOC_00472 3.71e-182 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
LEOBILOC_00473 3.26e-181 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
LEOBILOC_00476 5.8e-110 - - - S ko:K06343,ko:K06344 - ko00000 Spore coat protein
LEOBILOC_00477 1.1e-78 yjcA - - S - - - Protein of unknown function (DUF1360)
LEOBILOC_00479 8.08e-105 - - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LEOBILOC_00480 2.91e-109 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
LEOBILOC_00481 2.45e-244 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
LEOBILOC_00482 2.49e-75 spoVAE - - S ko:K06407 - ko00000 stage V sporulation protein
LEOBILOC_00484 2.02e-52 spoVIF - - S - - - Stage VI sporulation protein F
LEOBILOC_00486 4.83e-98 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEOBILOC_00487 4.73e-123 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
LEOBILOC_00488 9.11e-182 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
LEOBILOC_00496 2.27e-215 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
LEOBILOC_00497 3.11e-217 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LEOBILOC_00498 1.66e-271 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
LEOBILOC_00499 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Papain family cysteine protease
LEOBILOC_00500 8.24e-43 - - - S - - - Domain of unknown function (DUF4177)
LEOBILOC_00501 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
LEOBILOC_00502 7.49e-197 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LEOBILOC_00503 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LEOBILOC_00504 1.14e-139 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
LEOBILOC_00505 3.02e-254 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
LEOBILOC_00506 0.0 ykoS - - - - - - -
LEOBILOC_00507 7.51e-238 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
LEOBILOC_00508 1.5e-88 yngA - - S - - - GtrA-like protein
LEOBILOC_00509 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LEOBILOC_00510 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LEOBILOC_00511 6.51e-161 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
LEOBILOC_00512 2.21e-38 - - - S - - - Domain of unknown function (DUF4305)
LEOBILOC_00513 2.26e-167 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LEOBILOC_00514 1.97e-159 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LEOBILOC_00516 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
LEOBILOC_00518 3.3e-236 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LEOBILOC_00519 1.35e-106 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LEOBILOC_00520 1.24e-165 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
LEOBILOC_00521 1.41e-108 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
LEOBILOC_00523 2.38e-15 - - - - - - - -
LEOBILOC_00524 1.03e-106 - - - S - - - cellulose binding
LEOBILOC_00525 1.55e-274 - - - G - - - Major facilitator Superfamily
LEOBILOC_00526 1.9e-108 - - - S - - - Pfam:DUF1399
LEOBILOC_00527 1.26e-161 - - - EGP - - - COG2814 Arabinose efflux permease
LEOBILOC_00528 1.69e-177 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LEOBILOC_00529 0.0 - - - NT ko:K03406,ko:K06595 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Chemoreceptor zinc-binding domain
LEOBILOC_00530 1.05e-153 - - - S - - - Putative adhesin
LEOBILOC_00531 2.37e-124 XK27_04830 - - S - - - Protein of unknown function (DUF1700)
LEOBILOC_00532 8.76e-73 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
LEOBILOC_00533 7.93e-278 - - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LEOBILOC_00534 0.0 - - - EGP - - - Major facilitator superfamily
LEOBILOC_00535 1.22e-132 - - - Q - - - Isochorismatase family
LEOBILOC_00536 1.58e-138 - - - K - - - Transcriptional regulator
LEOBILOC_00537 2.47e-77 - - - - - - - -
LEOBILOC_00538 1.32e-161 - - - - - - - -
LEOBILOC_00539 5.64e-59 ltaA 4.1.2.48 - E ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 L-allo-threonine aldolase activity
LEOBILOC_00540 2.01e-267 - - - EGP - - - Major Facilitator Superfamily
LEOBILOC_00541 5.81e-218 - - - F - - - ATP-grasp domain
LEOBILOC_00543 1.17e-271 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LEOBILOC_00544 9.96e-69 ykvR - - S - - - Protein of unknown function (DUF3219)
LEOBILOC_00545 2.52e-239 ywcH1 - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEOBILOC_00547 9.02e-277 - - - G - - - Major Facilitator Superfamily
LEOBILOC_00549 4.14e-126 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LEOBILOC_00551 5.18e-114 - - - J - - - Acetyltransferase (GNAT) domain
LEOBILOC_00552 1.14e-51 - - - L - - - PFAM Transposase, IS4-like
LEOBILOC_00553 1.14e-91 yxiE - - T - - - Belongs to the universal stress protein A family
LEOBILOC_00554 4.69e-39 - - - - - - - -
LEOBILOC_00555 1.56e-100 - - - - - - - -
LEOBILOC_00556 3.45e-286 yfkA - - S - - - YfkB-like domain
LEOBILOC_00558 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
LEOBILOC_00559 7.16e-257 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
LEOBILOC_00560 5.68e-114 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
LEOBILOC_00561 3.37e-112 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
LEOBILOC_00562 1.47e-225 ykvZ - - K - - - Transcriptional regulator
LEOBILOC_00563 5.86e-122 hxlB 4.1.2.43, 5.3.1.27 - M ko:K08093,ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 arabinose-5-phosphate isomerase activity
LEOBILOC_00564 1.84e-189 ykrA - - S - - - hydrolases of the HAD superfamily
LEOBILOC_00566 1.25e-189 - 3.1.1.1 - S ko:K03928 - ko00000,ko01000 BAAT / Acyl-CoA thioester hydrolase C terminal
LEOBILOC_00567 9.83e-191 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
LEOBILOC_00568 9.24e-60 - - - L ko:K07483 - ko00000 COG2963 Transposase and inactivated derivatives
LEOBILOC_00569 2.07e-147 - - - M - - - Spore coat protein
LEOBILOC_00570 1.1e-176 - - - I - - - alpha/beta hydrolase fold
LEOBILOC_00571 6.41e-197 morA - - S - - - Aldo/keto reductase family
LEOBILOC_00572 4.06e-127 - 1.5.1.38 - S ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 ko00000,ko00001,ko01000 FMN reductase
LEOBILOC_00573 1.62e-314 yhaO - - L ko:K03547 - ko00000,ko03400 Calcineurin-like phosphoesterase superfamily domain
LEOBILOC_00574 0.0 - - - L - - - AAA domain
LEOBILOC_00575 8.37e-198 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
LEOBILOC_00576 2.9e-310 - - - V - - - Mate efflux family protein
LEOBILOC_00577 2.42e-87 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
LEOBILOC_00578 2.34e-77 - - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
LEOBILOC_00579 1.77e-143 yhbD - - K - - - Protein of unknown function (DUF4004)
LEOBILOC_00580 6.7e-284 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LEOBILOC_00581 1.06e-139 - 4.1.3.17 - H ko:K10218 ko00362,ko00660,ko01120,map00362,map00660,map01120 ko00000,ko00001,ko01000 Methyltransferase
LEOBILOC_00582 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Alpha-galactosidase
LEOBILOC_00583 2.93e-67 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LEOBILOC_00584 0.0 - 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEOBILOC_00585 3.29e-187 ubiE - - Q - - - Methyltransferase type 11
LEOBILOC_00586 2.94e-262 - - - M - - - Glycosyl hydrolases family 25
LEOBILOC_00587 1.47e-102 - - - - - - - -
LEOBILOC_00588 1.28e-174 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Short-chain dehydrogenase reductase sdr
LEOBILOC_00589 2.62e-300 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
LEOBILOC_00590 2.89e-175 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
LEOBILOC_00591 1e-222 ybaS - - S - - - Na -dependent transporter
LEOBILOC_00593 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LEOBILOC_00594 4.13e-314 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
LEOBILOC_00596 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
LEOBILOC_00597 0.0 yhcA5 - - EGP - - - the major facilitator superfamily
LEOBILOC_00598 3.83e-147 emrA - - V - - - Barrel-sandwich domain of CusB or HlyD membrane-fusion
LEOBILOC_00599 2.1e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LEOBILOC_00600 1.13e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LEOBILOC_00601 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LEOBILOC_00602 1.2e-122 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LEOBILOC_00603 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
LEOBILOC_00604 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LEOBILOC_00605 6.7e-72 yrzD - - S - - - Post-transcriptional regulator
LEOBILOC_00606 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEOBILOC_00607 3.8e-143 yrbG - - S - - - membrane
LEOBILOC_00608 3.24e-84 yrzE - - S - - - Protein of unknown function (DUF3792)
LEOBILOC_00609 7.67e-69 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
LEOBILOC_00610 3.07e-287 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LEOBILOC_00611 1.42e-246 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LEOBILOC_00612 6.43e-37 yrzS - - S - - - Protein of unknown function (DUF2905)
LEOBILOC_00613 5.06e-235 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LEOBILOC_00614 3.07e-136 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LEOBILOC_00615 1.09e-162 yebC - - K - - - transcriptional regulatory protein
LEOBILOC_00616 5.31e-241 - - - M - - - choline kinase involved in LPS biosynthesis
LEOBILOC_00617 1.17e-226 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
LEOBILOC_00618 2.19e-124 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
LEOBILOC_00619 9.91e-205 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
LEOBILOC_00620 6.2e-98 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
LEOBILOC_00621 1.83e-314 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LEOBILOC_00622 3.43e-128 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
LEOBILOC_00623 5.39e-62 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
LEOBILOC_00624 2.31e-69 ysxB - - J ko:K07584 - ko00000 ribosomal protein
LEOBILOC_00625 2.58e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
LEOBILOC_00626 0.0 rng - - J ko:K08301 - ko00000,ko01000,ko03009,ko03019 ribonuclease, Rne Rng family
LEOBILOC_00627 9.19e-209 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
LEOBILOC_00628 1.97e-175 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
LEOBILOC_00629 1.89e-187 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
LEOBILOC_00630 1.96e-156 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LEOBILOC_00631 1.29e-112 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
LEOBILOC_00632 7.02e-188 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
LEOBILOC_00633 1.34e-233 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
LEOBILOC_00634 1.33e-157 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
LEOBILOC_00635 7.62e-223 spoIIB - - - ko:K06380 - ko00000 -
LEOBILOC_00636 1.39e-181 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
LEOBILOC_00637 2.51e-145 - - - - ko:K02664 - ko00000,ko02035,ko02044 -
LEOBILOC_00638 3.4e-106 - - - NU ko:K02663 - ko00000,ko02035,ko02044 PFAM Fimbrial assembly family protein
LEOBILOC_00639 6.75e-245 - - - NU ko:K02662,ko:K02663 - ko00000,ko02035,ko02044 COG4972 Tfp pilus assembly protein, ATPase PilM
LEOBILOC_00640 3.92e-66 - - - NU ko:K02650 ko02020,map02020 ko00000,ko00001,ko02035,ko02044 cell adhesion
LEOBILOC_00641 2.74e-267 pilC - - NU ko:K02653 - ko00000,ko02035,ko02044 type II secretion system
LEOBILOC_00642 1.13e-247 pilT - - NU ko:K02669 - ko00000,ko02035,ko02044 twitching motility protein
LEOBILOC_00643 0.0 pilB - - NU ko:K02243,ko:K02652 - ko00000,ko00002,ko02035,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LEOBILOC_00644 2.46e-279 - - - V - - - G5
LEOBILOC_00645 1.17e-163 - - - S - - - PRC-barrel domain
LEOBILOC_00646 2.16e-270 - - - - - - - -
LEOBILOC_00647 1.85e-307 - - - NU - - - Pilus assembly protein PilX
LEOBILOC_00648 6.95e-111 - - - - - - - -
LEOBILOC_00649 9.73e-06 - - - NU - - - Prokaryotic N-terminal methylation motif
LEOBILOC_00650 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
LEOBILOC_00651 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LEOBILOC_00652 3.74e-36 - - - - - - - -
LEOBILOC_00653 2.01e-286 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LEOBILOC_00654 2.45e-271 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
LEOBILOC_00655 1.69e-314 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
LEOBILOC_00656 2.94e-235 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
LEOBILOC_00657 6.85e-182 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
LEOBILOC_00658 7e-215 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
LEOBILOC_00659 1.68e-188 hemX - - O ko:K02497 - ko00000 cytochrome C
LEOBILOC_00660 1.04e-306 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LEOBILOC_00661 3.11e-116 ysxD - - - - - - -
LEOBILOC_00662 8.22e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
LEOBILOC_00663 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LEOBILOC_00664 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
LEOBILOC_00665 1.2e-299 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LEOBILOC_00666 4.71e-284 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LEOBILOC_00667 1.39e-231 ysoA - - O - - - COG0457 FOG TPR repeat
LEOBILOC_00668 2.75e-95 - - - S - - - Protein of unknown function (DUF2512)
LEOBILOC_00669 3.61e-61 - - - - - - - -
LEOBILOC_00671 4.92e-120 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
LEOBILOC_00672 6.18e-137 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LEOBILOC_00673 2.27e-245 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
LEOBILOC_00674 8.98e-34 yraE - - - ko:K06440 - ko00000 -
LEOBILOC_00675 2.24e-56 yraD - - M ko:K06439 - ko00000 Spore coat protein
LEOBILOC_00676 5.89e-280 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LEOBILOC_00677 6.26e-80 yraF - - M - - - Spore coat protein
LEOBILOC_00678 1.78e-42 yraG - - S ko:K06440 - ko00000 Spore Coat Protein
LEOBILOC_00679 7.48e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
LEOBILOC_00680 1.35e-102 ysmB - - K - - - transcriptional
LEOBILOC_00681 4.34e-121 - - - S - - - GDYXXLXY protein
LEOBILOC_00682 2.11e-249 - - - S - - - Predicted membrane protein (DUF2157)
LEOBILOC_00684 3.8e-43 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
LEOBILOC_00685 1.33e-114 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
LEOBILOC_00686 8.45e-193 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
LEOBILOC_00687 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
LEOBILOC_00688 5.93e-135 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
LEOBILOC_00689 4.17e-107 yslB - - S - - - Protein of unknown function (DUF2507)
LEOBILOC_00690 1.86e-285 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LEOBILOC_00691 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LEOBILOC_00692 9.61e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LEOBILOC_00693 4.08e-222 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
LEOBILOC_00694 1.13e-173 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
LEOBILOC_00695 3.14e-180 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
LEOBILOC_00696 5.75e-135 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
LEOBILOC_00697 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LEOBILOC_00698 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LEOBILOC_00699 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
LEOBILOC_00700 1.05e-114 yshB - - S - - - membrane protein, required for colicin V production
LEOBILOC_00701 1.31e-56 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LEOBILOC_00702 7.57e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEOBILOC_00703 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEOBILOC_00704 1.56e-256 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LEOBILOC_00707 1.23e-174 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEOBILOC_00708 2.36e-42 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
LEOBILOC_00709 2.31e-98 - - - - - - - -
LEOBILOC_00710 3.41e-62 - - - S - - - Domain of unknown function (DUF5085)
LEOBILOC_00711 4.5e-19 - - - - - - - -
LEOBILOC_00712 5e-105 - - - - - - - -
LEOBILOC_00713 4.27e-12 - - - - - - - -
LEOBILOC_00714 2.62e-12 - - - - - - - -
LEOBILOC_00715 1.07e-151 - - - T - - - ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LEOBILOC_00716 9.18e-26 - - - - - - - -
LEOBILOC_00718 1.21e-74 - - - K - - - LysR substrate binding domain
LEOBILOC_00719 2.11e-130 - 1.1.1.413 - IQ ko:K22322 - ko00000,ko01000 KR domain
LEOBILOC_00720 4.89e-183 - - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LEOBILOC_00721 1.98e-71 yjgB - - S - - - Domain of unknown function (DUF4309)
LEOBILOC_00722 4.98e-155 M1-1017 - - S - - - Protein of unknown function (DUF1129)
LEOBILOC_00723 1.01e-73 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
LEOBILOC_00724 1.1e-15 - - - S - - - NADPH-dependent FMN reductase
LEOBILOC_00725 7.8e-163 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LEOBILOC_00726 2.18e-218 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LEOBILOC_00727 1.33e-129 - - - S ko:K19784 - ko00000 NAD(P)H-dependent FMN reductase
LEOBILOC_00728 6.49e-210 - - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
LEOBILOC_00729 5.27e-235 - - - C - - - COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LEOBILOC_00730 3.12e-120 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEOBILOC_00731 0.0 - - - M - - - O-Antigen ligase
LEOBILOC_00732 1.58e-100 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
LEOBILOC_00734 3.16e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LEOBILOC_00735 4.3e-36 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
LEOBILOC_00736 8.37e-145 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LEOBILOC_00737 1.64e-284 - - - G - - - Transmembrane secretion effector
LEOBILOC_00738 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LEOBILOC_00739 1.15e-197 ytxC - - S - - - YtxC-like family
LEOBILOC_00740 6.1e-227 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
LEOBILOC_00741 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
LEOBILOC_00742 4.02e-104 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LEOBILOC_00743 4.08e-247 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LEOBILOC_00744 4.88e-133 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LEOBILOC_00745 5.02e-141 ytaF - - P - - - Probably functions as a manganese efflux pump
LEOBILOC_00746 7.49e-198 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LEOBILOC_00747 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LEOBILOC_00748 2.75e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
LEOBILOC_00749 2.57e-311 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
LEOBILOC_00750 1.08e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LEOBILOC_00751 5.22e-97 - - - S - - - Membrane
LEOBILOC_00752 2.16e-231 ytvI - - S - - - sporulation integral membrane protein YtvI
LEOBILOC_00753 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
LEOBILOC_00754 5.39e-224 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LEOBILOC_00755 1.33e-226 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LEOBILOC_00756 5.52e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LEOBILOC_00757 3.63e-288 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
LEOBILOC_00758 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
LEOBILOC_00759 1.23e-69 ytrH - - S - - - Sporulation protein YtrH
LEOBILOC_00760 7.28e-117 ytrI - - - - - - -
LEOBILOC_00761 1.38e-222 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
LEOBILOC_00762 6.85e-52 ytpI - - S - - - YtpI-like protein
LEOBILOC_00763 1.86e-302 ytoI - - K - - - transcriptional regulator containing CBS domains
LEOBILOC_00764 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
LEOBILOC_00765 4.51e-261 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
LEOBILOC_00766 8.71e-258 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
LEOBILOC_00767 4.68e-104 uspA - - T - - - Belongs to the universal stress protein A family
LEOBILOC_00768 6.19e-201 - - - S - - - EcsC protein family
LEOBILOC_00769 2.07e-280 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEOBILOC_00770 6.12e-232 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
LEOBILOC_00771 4.75e-117 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LEOBILOC_00772 1.39e-96 ytfJ - - S - - - Sporulation protein YtfJ
LEOBILOC_00773 8.39e-154 ytfI - - S - - - Protein of unknown function (DUF2953)
LEOBILOC_00774 2.13e-112 yteJ - - S - - - RDD family
LEOBILOC_00775 1.85e-240 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
LEOBILOC_00776 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LEOBILOC_00777 7.27e-38 B4168_3115 - - S ko:K06419 - ko00000 spore protein
LEOBILOC_00778 1.59e-287 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LEOBILOC_00779 2.38e-273 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LEOBILOC_00780 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LEOBILOC_00781 1.07e-151 yttP - - K - - - Transcriptional regulator
LEOBILOC_00782 2.3e-111 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
LEOBILOC_00783 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
LEOBILOC_00784 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LEOBILOC_00785 4.01e-236 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
LEOBILOC_00786 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
LEOBILOC_00787 0.0 - - - KT - - - Transcriptional regulator
LEOBILOC_00788 1.4e-301 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LEOBILOC_00789 3.86e-196 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LEOBILOC_00790 1.75e-62 - - - L ko:K07496 - ko00000 Transposase
LEOBILOC_00791 1.33e-100 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
LEOBILOC_00792 5.71e-181 zurM - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LEOBILOC_00793 5.46e-183 zurA - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LEOBILOC_00794 1.94e-27 yqfT - - S - - - Protein of unknown function (DUF2624)
LEOBILOC_00795 3.61e-221 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
LEOBILOC_00796 2.19e-217 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LEOBILOC_00797 7.05e-306 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LEOBILOC_00799 1.66e-09 yqfQ - - S - - - YqfQ-like protein
LEOBILOC_00800 2.81e-231 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LEOBILOC_00801 2.86e-268 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LEOBILOC_00802 1.43e-144 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
LEOBILOC_00803 1.79e-84 cccA - - C ko:K13300 - ko00000 Cytochrome C oxidase, cbb3-type, subunit III
LEOBILOC_00804 1.52e-53 - - - L - - - PFAM Transposase, IS4-like
LEOBILOC_00805 4.26e-131 ldhA 1.1.1.28 - CH ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
LEOBILOC_00806 1.7e-45 ldhA 1.1.1.28 - CH ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
LEOBILOC_00807 4.27e-24 - - - K - - - ArsR family transcriptional regulator
LEOBILOC_00808 1.08e-187 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
LEOBILOC_00809 1.13e-58 ldhA 1.1.1.28 - CH ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
LEOBILOC_00810 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
LEOBILOC_00811 4.07e-57 - - - - - - - -
LEOBILOC_00813 3.41e-182 - 4.1.1.77 - Q ko:K01617 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 COG3971 2-keto-4-pentenoate hydratase
LEOBILOC_00814 9.69e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
LEOBILOC_00815 3.03e-297 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LEOBILOC_00816 2.42e-160 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
LEOBILOC_00817 1.12e-99 - - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
LEOBILOC_00818 4.51e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
LEOBILOC_00819 6.94e-262 kinC 2.7.13.3 - T ko:K02491,ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
LEOBILOC_00820 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LEOBILOC_00821 2.92e-108 - - - - - - - -
LEOBILOC_00822 1.05e-183 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
LEOBILOC_00823 2.87e-39 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
LEOBILOC_00824 3.9e-27 - - - S - - - Stage 0 Sporulation Regulatory protein
LEOBILOC_00826 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LEOBILOC_00827 4.68e-104 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LEOBILOC_00828 1.24e-90 - - - S - - - Protein of unknown function (DUF1232)
LEOBILOC_00830 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
LEOBILOC_00831 3.38e-230 ykvI - - S - - - membrane
LEOBILOC_00832 9.45e-138 - - - S ko:K07052 - ko00000 Abortive infection protein
LEOBILOC_00833 6.02e-37 ykvS - - S - - - protein conserved in bacteria
LEOBILOC_00834 2.45e-48 - - - - - - - -
LEOBILOC_00835 2.6e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
LEOBILOC_00836 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LEOBILOC_00837 1.23e-179 fabG1 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEOBILOC_00838 4.34e-202 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
LEOBILOC_00839 1.38e-272 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LEOBILOC_00840 5.49e-207 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
LEOBILOC_00841 4.16e-112 ykyB - - S - - - YkyB-like protein
LEOBILOC_00842 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
LEOBILOC_00843 0.0 - - - T - - - Diguanylate cyclase
LEOBILOC_00844 9.15e-45 - - - - - - - -
LEOBILOC_00845 1.01e-179 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEOBILOC_00846 7.59e-215 - 3.5.1.4 - C ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Acetamidase
LEOBILOC_00847 7.13e-52 ykuJ - - S - - - protein conserved in bacteria
LEOBILOC_00848 7.02e-103 ykuL - - S - - - CBS domain
LEOBILOC_00849 4.04e-203 ccpC - - K - - - Transcriptional regulator
LEOBILOC_00850 2.06e-122 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LEOBILOC_00851 2.59e-280 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LEOBILOC_00852 1.25e-26 - - - S - - - YhfH-like protein
LEOBILOC_00853 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEOBILOC_00854 1.63e-39 ykzG - - S - - - Belongs to the UPF0356 family
LEOBILOC_00855 3.06e-261 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LEOBILOC_00856 2.48e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LEOBILOC_00857 1.41e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LEOBILOC_00858 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LEOBILOC_00859 5.15e-46 - - - - - - - -
LEOBILOC_00860 9.82e-09 - - - S - - - SR1 protein
LEOBILOC_00861 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
LEOBILOC_00863 2.12e-63 yktA - - S - - - Belongs to the UPF0223 family
LEOBILOC_00864 2.85e-153 yktB - - S - - - Belongs to the UPF0637 family
LEOBILOC_00865 3.19e-33 - - - - - - - -
LEOBILOC_00866 3.57e-194 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
LEOBILOC_00867 1.1e-34 - - - S - - - Family of unknown function (DUF5325)
LEOBILOC_00868 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
LEOBILOC_00869 2.12e-70 ylaH - - S - - - YlaH-like protein
LEOBILOC_00870 0.0 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
LEOBILOC_00871 1.87e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LEOBILOC_00872 1.4e-58 ylaN - - S - - - Belongs to the UPF0358 family
LEOBILOC_00873 1.89e-276 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LEOBILOC_00874 7.37e-224 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
LEOBILOC_00875 3.46e-212 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LEOBILOC_00876 3.71e-261 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
LEOBILOC_00877 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LEOBILOC_00878 2.95e-147 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
LEOBILOC_00879 1.39e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
LEOBILOC_00880 5.83e-225 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
LEOBILOC_00881 9.34e-85 ylbA - - S - - - YugN-like family
LEOBILOC_00882 1.22e-250 ylbC - - S - - - protein with SCP PR1 domains
LEOBILOC_00883 6.59e-111 - - - Q ko:K02614 ko00360,map00360 ko00000,ko00001,ko01000 protein, possibly involved in aromatic compounds catabolism
LEOBILOC_00884 2.04e-91 ylbD - - S - - - Putative coat protein
LEOBILOC_00885 5.16e-50 ylbE - - S - - - YlbE-like protein
LEOBILOC_00886 2.96e-82 - - - - - - - -
LEOBILOC_00888 2.14e-13 - - - - - - - -
LEOBILOC_00889 3.1e-96 ylbF - - S - - - Belongs to the UPF0342 family
LEOBILOC_00890 7.56e-62 ylbG - - S - - - UPF0298 protein
LEOBILOC_00891 7.42e-89 - - - S - - - Methylthioribose kinase
LEOBILOC_00892 1.08e-136 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
LEOBILOC_00893 1.09e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LEOBILOC_00894 5.25e-279 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
LEOBILOC_00895 1.43e-179 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
LEOBILOC_00896 6.18e-240 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
LEOBILOC_00897 6.37e-314 ylbM - - S - - - Belongs to the UPF0348 family
LEOBILOC_00898 1.14e-124 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
LEOBILOC_00899 7.12e-36 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
LEOBILOC_00900 2.51e-109 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
LEOBILOC_00901 1.12e-119 ylbP - - K - - - n-acetyltransferase
LEOBILOC_00902 2.95e-207 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LEOBILOC_00903 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LEOBILOC_00904 1.96e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
LEOBILOC_00905 1.04e-220 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LEOBILOC_00906 1.61e-67 ftsL - - D - - - Essential cell division protein
LEOBILOC_00907 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LEOBILOC_00908 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
LEOBILOC_00909 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LEOBILOC_00910 1.73e-102 - - - M - - - UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LEOBILOC_00911 2.75e-219 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LEOBILOC_00912 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LEOBILOC_00913 1.17e-248 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LEOBILOC_00914 9.87e-262 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LEOBILOC_00915 1.19e-156 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LEOBILOC_00916 5.93e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LEOBILOC_00917 1.59e-247 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LEOBILOC_00918 1.21e-214 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
LEOBILOC_00919 5.54e-156 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEOBILOC_00920 7.67e-177 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEOBILOC_00921 3.74e-58 ylmC - - S - - - sporulation protein
LEOBILOC_00922 3.37e-111 - - - M - - - 3D domain
LEOBILOC_00923 7e-206 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
LEOBILOC_00924 3.99e-158 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LEOBILOC_00925 2.44e-99 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LEOBILOC_00926 3e-54 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
LEOBILOC_00927 6.37e-185 ylmH - - S - - - conserved protein, contains S4-like domain
LEOBILOC_00928 1.73e-96 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
LEOBILOC_00929 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LEOBILOC_00931 2.25e-105 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LEOBILOC_00932 4.8e-223 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LEOBILOC_00933 7.36e-116 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LEOBILOC_00934 7.02e-214 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
LEOBILOC_00935 1.74e-311 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LEOBILOC_00936 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
LEOBILOC_00937 3.29e-187 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LEOBILOC_00938 2.06e-218 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LEOBILOC_00939 2.91e-165 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LEOBILOC_00940 2.51e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LEOBILOC_00941 3.74e-284 gltT - - C - - - Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEOBILOC_00942 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LEOBILOC_00943 3.05e-199 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
LEOBILOC_00944 1.5e-294 pbuG - - S ko:K06901 - ko00000,ko02000 permease
LEOBILOC_00945 0.000259 - - - D - - - nuclear chromosome segregation
LEOBILOC_00946 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
LEOBILOC_00947 8.23e-271 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LEOBILOC_00948 1.69e-151 yfiK - - K - - - Regulator
LEOBILOC_00949 1.96e-252 - - - T - - - Histidine kinase
LEOBILOC_00950 3.91e-217 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
LEOBILOC_00951 2.67e-252 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
LEOBILOC_00952 6.19e-263 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
LEOBILOC_00953 2.51e-286 - 1.13.11.4 - Q ko:K00450 ko00350,ko01100,ko01120,map00350,map01100,map01120 ko00000,ko00001,ko01000 Cupin domain
LEOBILOC_00954 7.3e-111 - - - S - - - DinB superfamily
LEOBILOC_00955 1.54e-222 - 3.7.1.5 - Q ko:K16164 ko00350,ko01100,ko01120,map00350,map01100,map01120 ko00000,ko00001,ko01000 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
LEOBILOC_00956 4.28e-180 - - - K - - - helix_turn_helix isocitrate lyase regulation
LEOBILOC_00957 7.73e-74 - - - - - - - -
LEOBILOC_00958 2.16e-194 - 1.14.13.127 - CH ko:K05712 ko00360,ko01120,ko01220,map00360,map01120,map01220 ko00000,ko00001,ko00002,ko01000 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LEOBILOC_00959 1.07e-94 - - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
LEOBILOC_00960 3.5e-271 - 6.2.1.3, 6.2.1.34, 6.2.1.48 - IQ ko:K00666,ko:K01897,ko:K02182,ko:K12508 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LEOBILOC_00961 3.98e-83 - 6.2.1.3, 6.2.1.34, 6.2.1.48 - IQ ko:K00666,ko:K01897,ko:K02182,ko:K12508 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LEOBILOC_00962 7.74e-278 thlA 2.3.1.16, 2.3.1.9 - I ko:K00626,ko:K07508 ko00062,ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00062,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
LEOBILOC_00963 1.33e-182 crt 4.2.1.17 - I ko:K01715 ko00650,ko01200,map00650,map01200 ko00000,ko00001,ko01000 Enoyl-CoA hydratase/isomerase
LEOBILOC_00964 9.08e-201 hbd 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
LEOBILOC_00965 4.74e-211 - - - QT - - - Domain present in phytochromes and cGMP-specific phosphodiesterases.
LEOBILOC_00966 8.13e-277 - - - EGP ko:K05548 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
LEOBILOC_00967 5.43e-183 - - - K - - - helix_turn_helix isocitrate lyase regulation
LEOBILOC_00968 2.44e-208 - - - Q - - - Fumarylacetoacetate (FAA) hydrolase family
LEOBILOC_00969 2.34e-174 - 1.13.11.4 - Q ko:K00450 ko00350,ko01100,ko01120,map00350,map01100,map01120 ko00000,ko00001,ko01000 AraC-like ligand binding domain
LEOBILOC_00970 1.46e-54 - 1.13.11.4 - Q ko:K00450 ko00350,ko01100,ko01120,map00350,map01100,map01120 ko00000,ko00001,ko01000 AraC-like ligand binding domain
LEOBILOC_00971 0.0 citT_1 - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
LEOBILOC_00972 5.95e-63 - - - L - - - deoxyribonuclease I activity
LEOBILOC_00973 0.0 XK27_11280 - - S - - - Psort location CytoplasmicMembrane, score
LEOBILOC_00976 2.26e-73 - - - - - - - -
LEOBILOC_00977 0.0 - - - L - - - PFAM Transposase, IS4-like
LEOBILOC_00978 0.0 - - - L - - - Transposase
LEOBILOC_00979 1.39e-58 - - - - - - - -
LEOBILOC_00980 0.0 yeeA - - V - - - Type II restriction enzyme, methylase subunits
LEOBILOC_00981 0.0 - - - KL - - - DEAD-like helicases superfamily
LEOBILOC_00982 4.95e-217 yeeC - - P - - - T5orf172
LEOBILOC_00983 3.73e-208 - - - S - - - Acetyl xylan esterase (AXE1)
LEOBILOC_00984 1.69e-164 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LEOBILOC_00985 9.37e-112 thiW - - S - - - Thiamine-precursor transporter protein (ThiW)
LEOBILOC_00986 1.43e-303 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
LEOBILOC_00987 0.0 - - - FH ko:K03457 - ko00000 Permease for cytosine/purines, uracil, thiamine, allantoin
LEOBILOC_00988 9.45e-104 yjhE - - S - - - Phage tail protein
LEOBILOC_00989 1.29e-172 - - - GKT ko:K03483 - ko00000,ko03000 transcriptional antiterminator
LEOBILOC_00990 8.19e-47 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG3414 Phosphotransferase system, galactitol-specific IIB component
LEOBILOC_00991 1.92e-262 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
LEOBILOC_00992 0.0 - - - L - - - Domain of unknown function (DUF4277)
LEOBILOC_00993 4.28e-59 - - - S - - - LXG domain of WXG superfamily
LEOBILOC_00994 5.15e-61 - - - - - - - -
LEOBILOC_00995 9.28e-212 - - - S - - - LXG domain of WXG superfamily
LEOBILOC_00996 8.51e-125 - - - - - - - -
LEOBILOC_00997 1.25e-97 - - - - - - - -
LEOBILOC_00998 2.93e-107 - - - S - - - Domain of unknown function (DUF5085)
LEOBILOC_01001 4.21e-242 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEOBILOC_01002 2.45e-39 yetF3 - - K - - - membrane
LEOBILOC_01003 4.12e-31 yetF3 - - K - - - membrane
LEOBILOC_01019 0.0 - - - G ko:K03292 - ko00000 MFS/sugar transport protein
LEOBILOC_01020 1.13e-101 - - - L ko:K07494 - ko00000 DDE superfamily endonuclease
LEOBILOC_01021 3.37e-20 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LEOBILOC_01022 3.09e-144 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Iron/manganese superoxide dismutases, alpha-hairpin domain
LEOBILOC_01023 3.61e-225 - - - C ko:K06871 - ko00000 4Fe-4S single cluster domain
LEOBILOC_01024 2.22e-148 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
LEOBILOC_01025 3.19e-112 tcaA - - S ko:K21463 - ko00000 response to antibiotic
LEOBILOC_01026 1.36e-30 - - - S - - - Double zinc ribbon
LEOBILOC_01030 8.32e-37 - - - K ko:K03481 - ko00000,ko03000 SIS domain
LEOBILOC_01031 3.37e-249 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
LEOBILOC_01032 2.32e-239 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
LEOBILOC_01033 6.75e-135 - - - M - - - Glycosyl hydrolases family 25
LEOBILOC_01037 1.1e-173 - - - L - - - Reverse transcriptase (RNA-dependent DNA polymerase)
LEOBILOC_01038 1.33e-49 - - - S - - - 23S rRNA-intervening sequence protein
LEOBILOC_01039 8.28e-146 - - - S - - - Sulfatase-modifying factor enzyme 1
LEOBILOC_01040 3.39e-48 - - - - - - - -
LEOBILOC_01041 7.8e-54 - - - - - - - -
LEOBILOC_01042 1.94e-29 - - - - - - - -
LEOBILOC_01043 9.1e-84 - - - - - - - -
LEOBILOC_01044 5.93e-174 - - - S - - - homolog of phage Mu protein gp47
LEOBILOC_01045 3.63e-20 - - - S - - - Protein of unknown function (DUF2634)
LEOBILOC_01046 3.34e-29 - - - - - - - -
LEOBILOC_01047 4.54e-95 - - - - - - - -
LEOBILOC_01048 2.4e-44 - - - - - - - -
LEOBILOC_01049 2.86e-39 - - - S - - - HNH endonuclease
LEOBILOC_01050 1.83e-42 - - - M - - - LysM domain
LEOBILOC_01051 6.15e-102 - - - D - - - phage tail tape measure protein
LEOBILOC_01052 2.34e-31 - - - - - - - -
LEOBILOC_01054 3e-88 - - - S - - - Protein of unknown function (DUF3383)
LEOBILOC_01055 2.52e-29 - - - - - - - -
LEOBILOC_01057 4e-85 - - - - - - - -
LEOBILOC_01060 1.64e-101 Z012_11565 - - S - - - Uncharacterized protein conserved in bacteria (DUF2184)
LEOBILOC_01061 2.23e-37 - - - - - - - -
LEOBILOC_01062 3.15e-144 - - - S ko:K09960 - ko00000 Uncharacterized protein conserved in bacteria (DUF2213)
LEOBILOC_01063 5.15e-72 - - - S - - - Phage Mu protein F like protein
LEOBILOC_01064 9.03e-195 - - - S ko:K09961 - ko00000 Protein of unknown function (DUF1073)
LEOBILOC_01065 2.85e-238 - - - S - - - Terminase-like family
LEOBILOC_01066 5.52e-63 - - - L - - - transposase activity
LEOBILOC_01068 4.46e-57 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LEOBILOC_01069 0.000955 - - - - - - - -
LEOBILOC_01070 1.57e-124 - 2.1.1.72 - L ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 D12 class N6 adenine-specific DNA methyltransferase
LEOBILOC_01073 1.85e-178 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
LEOBILOC_01074 2.46e-22 - - - - - - - -
LEOBILOC_01075 1.33e-61 - - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LEOBILOC_01076 6.63e-82 - - - L - - - Replication initiation and membrane attachment
LEOBILOC_01077 2.28e-125 - - - S - - - Metallo-beta-lactamase superfamily
LEOBILOC_01078 7.59e-102 bet - - L - - - RecT family
LEOBILOC_01079 6.43e-297 - - - D - - - nuclear chromosome segregation
LEOBILOC_01085 1.63e-49 - - - - - - - -
LEOBILOC_01086 4.19e-135 - - - K - - - ORF6C domain
LEOBILOC_01087 1.17e-05 - - - K - - - XRE family transcriptional regulator
LEOBILOC_01088 4.37e-45 - - - K - - - transcriptional
LEOBILOC_01089 2.86e-35 - - - E - - - Pfam:DUF955
LEOBILOC_01092 2.71e-38 yhjA - - S - - - Excalibur calcium-binding domain
LEOBILOC_01094 7.49e-118 - - - L - - - Arm DNA-binding domain
LEOBILOC_01095 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEOBILOC_01096 0.0 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEOBILOC_01097 1.95e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LEOBILOC_01098 3.45e-191 - - - Q - - - N-acetyltransferase
LEOBILOC_01100 2.57e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
LEOBILOC_01102 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEOBILOC_01103 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LEOBILOC_01104 2.67e-62 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEOBILOC_01105 4.81e-312 aceA 4.1.3.1 - C ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Isocitrate lyase
LEOBILOC_01106 0.0 aceB 2.3.3.9 - C ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the malate synthase family
LEOBILOC_01107 2.23e-280 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
LEOBILOC_01108 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LEOBILOC_01109 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
LEOBILOC_01110 9.07e-167 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LEOBILOC_01111 6.09e-70 yerC - - S - - - protein conserved in bacteria
LEOBILOC_01112 1.86e-243 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
LEOBILOC_01113 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
LEOBILOC_01114 3.43e-49 - - - S - - - Protein of unknown function (DUF2892)
LEOBILOC_01115 1.66e-287 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
LEOBILOC_01116 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
LEOBILOC_01117 2.73e-133 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LEOBILOC_01118 2.86e-244 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
LEOBILOC_01119 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LEOBILOC_01120 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEOBILOC_01121 8.37e-161 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEOBILOC_01122 5.19e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEOBILOC_01123 3.37e-160 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
LEOBILOC_01124 5.79e-316 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LEOBILOC_01125 3.69e-278 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LEOBILOC_01126 1.57e-106 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LEOBILOC_01127 7.94e-41 yebG - - S - - - NETI protein
LEOBILOC_01128 1.09e-117 yebE - - S - - - UPF0316 protein
LEOBILOC_01129 1.52e-151 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 dithiol-disulfide isomerase involved in polyketide biosynthesis
LEOBILOC_01133 0.0 - - - L - - - Mu transposase, C-terminal
LEOBILOC_01134 8.42e-194 - - - U - - - AAA domain
LEOBILOC_01135 1.07e-208 ygxA - - S - - - Nucleotidyltransferase-like
LEOBILOC_01136 3.29e-75 ygzB - - S - - - UPF0295 protein
LEOBILOC_01137 3.99e-179 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
LEOBILOC_01138 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
LEOBILOC_01139 1.16e-210 - - - K - - - LysR substrate binding domain
LEOBILOC_01140 2.85e-107 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
LEOBILOC_01141 1.89e-129 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
LEOBILOC_01142 2.97e-86 - - - P ko:K08713 - ko00000,ko02000 Ion transport
LEOBILOC_01143 4.29e-313 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
LEOBILOC_01144 2.22e-214 ssuA - - P ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LEOBILOC_01145 5.87e-182 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LEOBILOC_01146 1.5e-185 ssuB - - P ko:K02049,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
LEOBILOC_01147 7.17e-146 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEOBILOC_01148 6.55e-289 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LEOBILOC_01149 2.57e-80 - - - - - - - -
LEOBILOC_01150 1.41e-53 yqhV - - S - - - Protein of unknown function (DUF2619)
LEOBILOC_01151 9.46e-240 ygaE - - S - - - Membrane
LEOBILOC_01152 1.98e-199 yleF - - K - - - transcriptional
LEOBILOC_01153 0.0 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LEOBILOC_01154 7.09e-196 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LEOBILOC_01155 6.5e-272 yleB 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
LEOBILOC_01156 7.29e-73 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
LEOBILOC_01157 4.51e-301 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
LEOBILOC_01158 5.7e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
LEOBILOC_01159 4.1e-49 ygaB - - S - - - YgaB-like protein
LEOBILOC_01160 2.95e-23 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
LEOBILOC_01161 1.13e-169 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEOBILOC_01162 4.18e-210 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
LEOBILOC_01163 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
LEOBILOC_01164 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
LEOBILOC_01165 2.29e-68 - - - S - - - YfzA-like protein
LEOBILOC_01166 1.93e-129 - - - S - - - ABC-2 family transporter protein
LEOBILOC_01167 3.06e-204 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LEOBILOC_01168 3.91e-31 sspK - - S ko:K06428 - ko00000 reproduction
LEOBILOC_01169 4.2e-240 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
LEOBILOC_01170 5.62e-275 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
LEOBILOC_01171 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LEOBILOC_01172 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
LEOBILOC_01173 0.0 - - - EGP - - - the major facilitator superfamily
LEOBILOC_01174 5.89e-145 - - - K - - - Bacterial regulatory proteins, tetR family
LEOBILOC_01175 1.44e-111 - - - K - - - Winged helix DNA-binding domain
LEOBILOC_01176 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
LEOBILOC_01177 3.65e-117 tasA - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
LEOBILOC_01178 1.75e-65 - - - S - - - Camelysin metallo-endopeptidase
LEOBILOC_01180 3e-87 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
LEOBILOC_01181 4.46e-53 - - - S - - - cell adhesion involved in biofilm formation
LEOBILOC_01182 1.24e-126 ywjB - - H - - - RibD C-terminal domain
LEOBILOC_01183 5.6e-08 - - - - - - - -
LEOBILOC_01184 8.96e-273 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
LEOBILOC_01185 6.28e-73 - - - S - - - DsrE/DsrF-like family
LEOBILOC_01186 7.5e-100 - - - - - - - -
LEOBILOC_01187 3.06e-237 - 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEOBILOC_01189 1.61e-226 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LEOBILOC_01190 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LEOBILOC_01191 2.29e-107 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
LEOBILOC_01192 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LEOBILOC_01193 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
LEOBILOC_01194 3.03e-169 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
LEOBILOC_01195 3.68e-295 - - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
LEOBILOC_01197 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
LEOBILOC_01198 6.36e-162 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
LEOBILOC_01199 4.78e-218 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
LEOBILOC_01200 2.61e-105 fld - - C ko:K03839 - ko00000 Flavodoxin
LEOBILOC_01201 3.57e-261 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LEOBILOC_01202 5.87e-177 - - - T ko:K21562 - ko00000,ko03000 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
LEOBILOC_01203 0.0 - 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
LEOBILOC_01204 7.15e-43 copZ - - P - - - Heavy-metal-associated domain
LEOBILOC_01206 0.0 nrdA 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEOBILOC_01207 2.29e-116 - - - C - - - Flavodoxin
LEOBILOC_01208 3.79e-249 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEOBILOC_01209 5.73e-143 - - - I - - - Belongs to the PlsY family
LEOBILOC_01210 3.73e-263 crtQ - - M ko:K10211 ko00906,map00906 ko00000,ko00001,ko01000 Glycosyl transferase family 21
LEOBILOC_01211 3.16e-206 - - - S - - - transposase or invertase
LEOBILOC_01212 1.14e-27 - - - S - - - transposase or invertase
LEOBILOC_01213 3.26e-25 - - - S - - - transposase or invertase
LEOBILOC_01214 1.8e-120 - - - Q - - - Thioesterase superfamily
LEOBILOC_01215 5.18e-221 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LEOBILOC_01216 8.58e-65 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
LEOBILOC_01217 2.27e-71 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
LEOBILOC_01218 2.67e-178 yfcA - - S ko:K07090 - ko00000 membrane transporter protein
LEOBILOC_01219 3.41e-233 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEOBILOC_01220 3.03e-235 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEOBILOC_01221 1.68e-227 fhuD9 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
LEOBILOC_01222 1.51e-194 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LEOBILOC_01223 6e-244 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
LEOBILOC_01224 8.08e-147 - - - - - - - -
LEOBILOC_01226 2.43e-145 - - - - - - - -
LEOBILOC_01227 3.77e-139 - - - - - - - -
LEOBILOC_01228 1.96e-165 yeeN - - K - - - transcriptional regulatory protein
LEOBILOC_01229 7.59e-245 - - - T ko:K17763 - ko00000,ko03021 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)
LEOBILOC_01230 5.12e-306 bbsG 1.3.8.7 - I ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 ko00000,ko00001,ko00002,ko01000 COG1960 Acyl-CoA dehydrogenases
LEOBILOC_01231 2.37e-175 - 1.1.1.69 - IQ ko:K00046 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEOBILOC_01232 1.87e-221 - 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LEOBILOC_01233 5.9e-91 - 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LEOBILOC_01234 2.1e-123 - - - K - - - Transcriptional regulator
LEOBILOC_01235 5.34e-89 - - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
LEOBILOC_01236 1.43e-251 - - - S - - - Phosphotransferase enzyme family
LEOBILOC_01237 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEOBILOC_01238 0.0 yobO - - M - - - Pectate lyase superfamily protein
LEOBILOC_01240 1.06e-179 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
LEOBILOC_01241 1.5e-180 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
LEOBILOC_01242 1.89e-171 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
LEOBILOC_01243 2.14e-140 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
LEOBILOC_01244 2.71e-125 ywhH - - S - - - Aminoacyl-tRNA editing domain
LEOBILOC_01245 5.71e-261 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
LEOBILOC_01246 0.0 - - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LEOBILOC_01248 1.26e-217 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LEOBILOC_01249 2.86e-213 - - - S - - - Nuclease-related domain
LEOBILOC_01250 8.73e-60 - - - - - - - -
LEOBILOC_01251 2.75e-35 - - - - - - - -
LEOBILOC_01252 3.3e-210 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
LEOBILOC_01253 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LEOBILOC_01254 7.15e-142 - - - M - - - Glycosyltransferase like family 2
LEOBILOC_01255 6.01e-218 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases C terminal
LEOBILOC_01256 1.19e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
LEOBILOC_01257 9.78e-257 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 GHMP kinases C terminal
LEOBILOC_01258 6.91e-149 yhfK - - GM - - - NmrA-like family
LEOBILOC_01259 4.64e-134 - - - K ko:K19505 - ko00000,ko03000 PTS system fructose IIA component
LEOBILOC_01260 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
LEOBILOC_01261 1.15e-153 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LEOBILOC_01262 3.54e-73 yaaQ - - S - - - protein conserved in bacteria
LEOBILOC_01263 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
LEOBILOC_01264 1.99e-237 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LEOBILOC_01265 3.27e-191 yaaT - - S - - - stage 0 sporulation protein
LEOBILOC_01266 1.06e-87 yabA - - L - - - Involved in initiation control of chromosome replication
LEOBILOC_01267 8.7e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
LEOBILOC_01268 2.98e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
LEOBILOC_01269 6.22e-210 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LEOBILOC_01270 1.01e-73 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
LEOBILOC_01271 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LEOBILOC_01272 4.17e-190 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
LEOBILOC_01273 9.16e-138 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LEOBILOC_01274 2.94e-204 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LEOBILOC_01275 1.66e-213 yabG - - S ko:K06436 - ko00000 peptidase
LEOBILOC_01276 8.34e-51 veg - - S - - - protein conserved in bacteria
LEOBILOC_01277 4.08e-47 sspF - - S ko:K06423 - ko00000 DNA topological change
LEOBILOC_01278 6.21e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LEOBILOC_01279 1.51e-199 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
LEOBILOC_01280 5.31e-82 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
LEOBILOC_01281 2.1e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
LEOBILOC_01283 4.33e-298 - - - S - - - Psort location CytoplasmicMembrane, score
LEOBILOC_01284 2.6e-54 - - - V ko:K02003 - ko00000,ko00002,ko02000 Abc transporter
LEOBILOC_01285 2.42e-105 - - - - - - - -
LEOBILOC_01286 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LEOBILOC_01287 1.09e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LEOBILOC_01288 2.06e-143 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LEOBILOC_01289 3.66e-132 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LEOBILOC_01290 1.79e-50 yabK - - S - - - Peptide ABC transporter permease
LEOBILOC_01291 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LEOBILOC_01292 2.8e-119 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
LEOBILOC_01293 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEOBILOC_01294 8.61e-251 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
LEOBILOC_01295 1.58e-55 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LEOBILOC_01296 1.23e-67 yabP - - S - - - Sporulation protein YabP
LEOBILOC_01297 6.37e-142 yabQ - - S - - - spore cortex biosynthesis protein
LEOBILOC_01298 1.43e-78 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
LEOBILOC_01299 7.71e-85 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
LEOBILOC_01301 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
LEOBILOC_01302 1.72e-162 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LEOBILOC_01303 3.24e-225 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
LEOBILOC_01304 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LEOBILOC_01305 2.89e-123 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
LEOBILOC_01306 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LEOBILOC_01307 1.1e-183 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LEOBILOC_01308 5.07e-204 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LEOBILOC_01309 2.18e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LEOBILOC_01310 2.74e-205 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LEOBILOC_01311 1.87e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LEOBILOC_01312 5.73e-125 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LEOBILOC_01313 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
LEOBILOC_01314 7.25e-303 - - - G - - - Major facilitator superfamily
LEOBILOC_01315 6.61e-190 - 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LEOBILOC_01316 0.0 ppdK 2.7.9.1 - G ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the PEP-utilizing enzyme family
LEOBILOC_01317 1.07e-90 - - - E - - - Glyoxalase
LEOBILOC_01318 1.28e-09 - - - S - - - Protein of unknown function (DUF4023)
LEOBILOC_01322 8.95e-251 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
LEOBILOC_01324 1.75e-133 - - - S - - - oxidoreductase activity
LEOBILOC_01325 5.69e-122 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LEOBILOC_01327 3.06e-262 icd 1.1.1.41, 1.1.1.42, 1.1.1.85 - CE ko:K00030,ko:K00031,ko:K00052 ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate/isopropylmalate dehydrogenase
LEOBILOC_01328 2.53e-204 - - - S - - - Methyltransferase domain
LEOBILOC_01332 6.9e-179 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
LEOBILOC_01333 8.73e-122 yvbK - - K - - - acetyltransferase
LEOBILOC_01334 2.37e-120 - - - J - - - acetyltransferase
LEOBILOC_01335 3.79e-89 - - - K - - - Acetyltransferase (GNAT) family
LEOBILOC_01336 3.69e-150 yneB - - L - - - resolvase
LEOBILOC_01337 1.94e-76 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
LEOBILOC_01338 3.86e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LEOBILOC_01339 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
LEOBILOC_01340 1.01e-86 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
LEOBILOC_01341 0.0 ypbR - - S - - - Dynamin family
LEOBILOC_01342 1.19e-45 - - - - - - - -
LEOBILOC_01343 2.08e-180 - - - O - - - prohibitin homologues
LEOBILOC_01344 1.96e-292 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
LEOBILOC_01345 7.86e-132 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LEOBILOC_01346 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LEOBILOC_01347 2.6e-280 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
LEOBILOC_01348 2.07e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LEOBILOC_01349 1.56e-132 ypsA - - S - - - Belongs to the UPF0398 family
LEOBILOC_01350 2.98e-62 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
LEOBILOC_01351 0.0 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
LEOBILOC_01352 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
LEOBILOC_01353 3.62e-100 hspc4-1 - - O - - - Belongs to the small heat shock protein (HSP20) family
LEOBILOC_01354 3.92e-110 yppG - - S - - - YppG-like protein
LEOBILOC_01355 1.13e-81 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
LEOBILOC_01358 6.73e-145 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LEOBILOC_01359 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LEOBILOC_01360 1.07e-159 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LEOBILOC_01361 8.7e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
LEOBILOC_01362 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
LEOBILOC_01363 6.12e-277 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LEOBILOC_01364 6.71e-102 ypmB - - S - - - protein conserved in bacteria
LEOBILOC_01365 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
LEOBILOC_01366 8.4e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LEOBILOC_01367 4.34e-202 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LEOBILOC_01368 9.39e-193 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
LEOBILOC_01369 9.42e-232 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LEOBILOC_01370 1.42e-289 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LEOBILOC_01371 1.51e-281 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
LEOBILOC_01372 3.29e-171 ypjG - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
LEOBILOC_01373 1.15e-191 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LEOBILOC_01374 3.2e-76 ypjD - - S - - - Nucleotide pyrophosphohydrolase
LEOBILOC_01375 1.65e-206 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LEOBILOC_01376 1.88e-106 queT - - S - - - QueT transporter
LEOBILOC_01377 3.83e-137 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
LEOBILOC_01378 5.43e-184 ypjB - - S - - - sporulation protein
LEOBILOC_01379 1.41e-140 ypjA - - S - - - membrane
LEOBILOC_01380 1.52e-190 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
LEOBILOC_01381 2.94e-164 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
LEOBILOC_01382 5.32e-129 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
LEOBILOC_01383 1.46e-111 ypiF - - S - - - Protein of unknown function (DUF2487)
LEOBILOC_01384 3.68e-130 ypiB - - S - - - Belongs to the UPF0302 family
LEOBILOC_01385 2.09e-304 ypiA - - S - - - COG0457 FOG TPR repeat
LEOBILOC_01386 1.07e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LEOBILOC_01387 3.72e-261 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
LEOBILOC_01388 1.03e-266 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LEOBILOC_01389 6.31e-79 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
LEOBILOC_01390 1.2e-263 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LEOBILOC_01391 5.92e-281 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LEOBILOC_01392 4.49e-187 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
LEOBILOC_01393 8.2e-102 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LEOBILOC_01394 1.32e-224 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LEOBILOC_01395 1.1e-164 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LEOBILOC_01396 1.74e-183 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
LEOBILOC_01397 1.85e-44 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
LEOBILOC_01398 1.54e-56 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LEOBILOC_01399 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LEOBILOC_01400 1.7e-175 yphF - - - - - - -
LEOBILOC_01401 7.83e-13 yphE - - S - - - Protein of unknown function (DUF2768)
LEOBILOC_01402 7.9e-246 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
LEOBILOC_01403 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
LEOBILOC_01404 2.35e-13 yphA - - - - - - -
LEOBILOC_01405 9.95e-21 - - - S - - - YpzI-like protein
LEOBILOC_01406 2.71e-260 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
LEOBILOC_01407 2.98e-153 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
LEOBILOC_01408 1.84e-153 ypfA - - M - - - Flagellar protein YcgR
LEOBILOC_01409 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
LEOBILOC_01410 4.17e-193 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
LEOBILOC_01411 4.87e-164 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
LEOBILOC_01412 2.85e-243 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
LEOBILOC_01413 2.28e-310 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LEOBILOC_01414 7.27e-145 - - - NOT ko:K16511 - ko00000 Negative regulator of genetic competence (MecA)
LEOBILOC_01415 5.66e-184 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
LEOBILOC_01416 8.41e-54 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
LEOBILOC_01417 1.24e-60 cotJB - - S ko:K06333 - ko00000 CotJB protein
LEOBILOC_01418 2.19e-135 cotJC - - P ko:K06334 - ko00000 Spore Coat
LEOBILOC_01419 1.47e-104 ypbF - - S - - - Protein of unknown function (DUF2663)
LEOBILOC_01421 6.25e-132 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
LEOBILOC_01422 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
LEOBILOC_01423 2.83e-261 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
LEOBILOC_01424 1.69e-54 fer - - C ko:K05337 - ko00000 Ferredoxin
LEOBILOC_01425 1.58e-125 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LEOBILOC_01426 1.29e-174 - - - M - - - COG0739 Membrane proteins related to metalloendopeptidases
LEOBILOC_01427 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LEOBILOC_01428 2.06e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEOBILOC_01429 2.11e-292 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
LEOBILOC_01430 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
LEOBILOC_01431 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
LEOBILOC_01432 5.61e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LEOBILOC_01433 3.96e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
LEOBILOC_01434 1.94e-124 spmA - - S ko:K06373 - ko00000 Spore maturation protein
LEOBILOC_01435 1.37e-271 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LEOBILOC_01436 7.85e-139 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LEOBILOC_01437 5.61e-169 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LEOBILOC_01438 1.28e-82 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEOBILOC_01439 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LEOBILOC_01440 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
LEOBILOC_01441 2.47e-137 spoVAEA - - S ko:K06407 - ko00000 Stage V sporulation protein AE
LEOBILOC_01442 1.75e-95 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
LEOBILOC_01443 4.9e-145 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
LEOBILOC_01444 8.59e-171 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEOBILOC_01445 8.55e-99 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
LEOBILOC_01446 4.34e-75 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
LEOBILOC_01447 2.58e-274 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LEOBILOC_01448 8.9e-216 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
LEOBILOC_01449 2.06e-46 - - - S - - - Protein of unknown function (DUF4227)
LEOBILOC_01450 1.5e-111 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
LEOBILOC_01451 1.54e-136 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
LEOBILOC_01452 5.16e-292 yqxK - - L - - - DNA helicase
LEOBILOC_01453 2.68e-129 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
LEOBILOC_01454 9.85e-08 - - - S - - - Protein of unknown function (DUF3936)
LEOBILOC_01455 9.58e-214 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
LEOBILOC_01456 1.86e-05 - - - S - - - Protein of unknown function (DUF3886)
LEOBILOC_01458 8.3e-142 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
LEOBILOC_01459 2.48e-275 yaaN - - P - - - Belongs to the TelA family
LEOBILOC_01461 4.98e-220 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
LEOBILOC_01462 3.02e-310 yaaH_2 - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
LEOBILOC_01463 9.23e-71 yqiX - - S - - - YolD-like protein
LEOBILOC_01464 4.05e-306 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LEOBILOC_01465 3.41e-188 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LEOBILOC_01466 1.17e-184 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LEOBILOC_01467 1.32e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LEOBILOC_01468 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LEOBILOC_01469 1.53e-286 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LEOBILOC_01470 5.2e-103 - - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
LEOBILOC_01471 6.14e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
LEOBILOC_01472 5.35e-123 yqjB - - S - - - protein conserved in bacteria
LEOBILOC_01473 4.43e-100 yqiW - - S - - - Belongs to the UPF0403 family
LEOBILOC_01474 4.55e-212 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
LEOBILOC_01475 2.66e-289 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LEOBILOC_01476 2.32e-233 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LEOBILOC_01477 1.25e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LEOBILOC_01478 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LEOBILOC_01479 2.53e-264 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LEOBILOC_01480 0.0 bkdR - - KT - - - Transcriptional regulator
LEOBILOC_01481 1.08e-47 yqzF - - S - - - Protein of unknown function (DUF2627)
LEOBILOC_01482 1.18e-170 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
LEOBILOC_01483 1.28e-181 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
LEOBILOC_01484 4.35e-300 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
LEOBILOC_01485 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
LEOBILOC_01486 9.2e-104 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
LEOBILOC_01487 4.13e-189 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
LEOBILOC_01488 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LEOBILOC_01489 1.52e-203 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LEOBILOC_01490 4.77e-42 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEOBILOC_01491 3.18e-313 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEOBILOC_01492 1.77e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LEOBILOC_01493 1.37e-81 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LEOBILOC_01494 3.73e-90 yqhY - - S - - - protein conserved in bacteria
LEOBILOC_01495 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LEOBILOC_01496 1.09e-105 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LEOBILOC_01497 1.12e-110 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
LEOBILOC_01498 1.55e-142 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
LEOBILOC_01499 2.58e-139 spoIIIAF - - S ko:K06395 - ko00000 stage III sporulation protein AF
LEOBILOC_01500 3.01e-258 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
LEOBILOC_01501 2.48e-78 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
LEOBILOC_01502 3.6e-38 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
LEOBILOC_01503 4.88e-112 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
LEOBILOC_01504 7.61e-218 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
LEOBILOC_01505 6.82e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LEOBILOC_01506 1.52e-242 yqhT 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
LEOBILOC_01507 2.25e-105 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
LEOBILOC_01508 2.13e-111 yqhR - - S - - - Conserved membrane protein YqhR
LEOBILOC_01509 2.32e-207 yqhQ - - S - - - Protein of unknown function (DUF1385)
LEOBILOC_01510 9.04e-18 yqhP - - - - - - -
LEOBILOC_01511 1.26e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
LEOBILOC_01512 1.07e-212 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
LEOBILOC_01513 2.68e-226 paaX - - K ko:K02616 - ko00000,ko03000 PaaX-like protein
LEOBILOC_01514 1.24e-278 pcaF 2.3.1.174, 2.3.1.223 - I ko:K02615 ko00360,ko01120,map00360,map01120 ko00000,ko00001,ko01000 Belongs to the thiolase family
LEOBILOC_01515 1.91e-195 hbd 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
LEOBILOC_01516 0.0 - 1.2.1.3, 1.2.1.8 - C ko:K00128,ko:K00130 ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LEOBILOC_01517 7.88e-34 paaG 5.3.3.18 - I ko:K15866 ko00360,ko01120,map00360,map01120 ko00000,ko00001,ko01000 Enoyl-CoA hydratase
LEOBILOC_01518 3.67e-126 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
LEOBILOC_01520 0.0 nrdA 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
LEOBILOC_01521 2.74e-205 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
LEOBILOC_01522 3.28e-87 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
LEOBILOC_01523 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LEOBILOC_01524 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LEOBILOC_01525 2.77e-271 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
LEOBILOC_01526 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
LEOBILOC_01527 5.31e-200 yqhG - - S - - - Bacterial protein YqhG of unknown function
LEOBILOC_01528 3.69e-14 yqzE - - S - - - YqzE-like protein
LEOBILOC_01529 2.04e-129 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LEOBILOC_01530 5.35e-81 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
LEOBILOC_01531 2.11e-108 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 COG4940 Competence protein ComGF
LEOBILOC_01533 2.18e-101 comGD - - NU ko:K02246 - ko00000,ko00002,ko02044 COG2165 Type II secretory pathway, pseudopilin PulG
LEOBILOC_01534 2.38e-66 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
LEOBILOC_01535 1.32e-224 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
LEOBILOC_01536 3.35e-268 comGA - - NU ko:K02243,ko:K02652 - ko00000,ko00002,ko02035,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LEOBILOC_01537 1.29e-168 - - - K - - - Helix-turn-helix domain
LEOBILOC_01538 1.31e-48 B4168_0554 - - S - - - Protein of unknown function (DUF2626)
LEOBILOC_01539 1.16e-158 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
LEOBILOC_01540 1.57e-30 yqgW - - S - - - Protein of unknown function (DUF2759)
LEOBILOC_01541 5.87e-229 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
LEOBILOC_01542 1.93e-39 yqgQ - - S - - - protein conserved in bacteria
LEOBILOC_01543 7.01e-267 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
LEOBILOC_01545 3.09e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LEOBILOC_01546 4.47e-69 yqzD - - - - - - -
LEOBILOC_01547 0.0 pbpA - - M ko:K21465 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
LEOBILOC_01548 3.53e-276 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
LEOBILOC_01549 1.12e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
LEOBILOC_01550 4.46e-72 - - - NU - - - Tfp pilus assembly protein FimV
LEOBILOC_01551 1.11e-259 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LEOBILOC_01552 1.48e-146 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
LEOBILOC_01553 2.53e-285 - - - L - - - Transposase
LEOBILOC_01554 0.0 - - - L - - - Domain of unknown function (DUF4277)
LEOBILOC_01555 3.96e-163 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LEOBILOC_01556 1.6e-77 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
LEOBILOC_01557 6.51e-122 padR - - K - - - transcriptional
LEOBILOC_01558 4.57e-124 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
LEOBILOC_01559 7.47e-148 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
LEOBILOC_01560 6.52e-93 ywnA - - K - - - Transcriptional regulator
LEOBILOC_01561 1.64e-16 - - - - - - - -
LEOBILOC_01562 3.35e-199 - - - S - - - Radical SAM superfamily
LEOBILOC_01563 7.47e-126 - - - O ko:K16922 - ko00000,ko01002 Peptidase M50
LEOBILOC_01564 3.38e-117 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LEOBILOC_01565 4.83e-116 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LEOBILOC_01566 1.17e-17 - - - - - - - -
LEOBILOC_01568 8.5e-29 - - - L ko:K07484 - ko00000 Transposase IS66 family
LEOBILOC_01569 9.48e-41 fnr - - K - - - Bacterial regulatory proteins, crp family
LEOBILOC_01570 4.03e-23 yeeD - - O - - - Belongs to the sulfur carrier protein TusA family
LEOBILOC_01571 2.71e-29 yeeE - - S ko:K07112 - ko00000 Sulphur transport
LEOBILOC_01572 0.0 yisV - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LEOBILOC_01573 1.22e-196 - - - S - - - transposase or invertase
LEOBILOC_01574 1.21e-48 yeeD - - O - - - Belongs to the sulfur carrier protein TusA family
LEOBILOC_01575 8.23e-247 yeeE - - S ko:K07112 - ko00000 Sulphur transport
LEOBILOC_01576 4.69e-107 - - - G - - - N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
LEOBILOC_01577 1.23e-160 - - - G - - - N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
LEOBILOC_01578 6.81e-221 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEOBILOC_01579 1.25e-10 - - - - ko:K07213 ko04978,map04978 ko00000,ko00001 -
LEOBILOC_01580 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
LEOBILOC_01581 2.26e-94 - - - V - - - ABC transporter transmembrane region
LEOBILOC_01589 1.57e-45 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEOBILOC_01590 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LEOBILOC_01592 2.97e-210 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
LEOBILOC_01593 5.4e-162 - 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LEOBILOC_01594 4.22e-267 - - - Q - - - Male sterility protein
LEOBILOC_01595 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LEOBILOC_01597 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LEOBILOC_01598 1.7e-236 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEOBILOC_01599 1.06e-277 sgaA - - E - - - COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
LEOBILOC_01600 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEOBILOC_01601 2.13e-232 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
LEOBILOC_01602 5.41e-275 - - - S - - - HAD-hyrolase-like
LEOBILOC_01603 7.28e-244 tdcB_1 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LEOBILOC_01604 1.87e-144 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LEOBILOC_01605 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LEOBILOC_01606 9.78e-257 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LEOBILOC_01607 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LEOBILOC_01608 5.17e-249 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LEOBILOC_01609 1.9e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
LEOBILOC_01610 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
LEOBILOC_01611 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
LEOBILOC_01612 7.47e-314 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LEOBILOC_01613 6.61e-196 rsbRD - - T ko:K17763 - ko00000,ko03021 STAS domain
LEOBILOC_01614 7.07e-311 - - - - - - - -
LEOBILOC_01615 1.38e-275 - - - O - - - Peptidase S53
LEOBILOC_01616 3.94e-49 XK26_06125 - - S - - - Transcriptional Coactivator p15 (PC4)
LEOBILOC_01618 7.44e-38 - - - D - - - nuclear chromosome segregation
LEOBILOC_01619 1.15e-49 - - - - - - - -
LEOBILOC_01620 1.09e-46 - - - - - - - -
LEOBILOC_01621 2.15e-126 - - - - - - - -
LEOBILOC_01622 5.69e-207 - - - S - - - transposase or invertase
LEOBILOC_01624 9.83e-106 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LEOBILOC_01625 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LEOBILOC_01626 1.76e-182 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
LEOBILOC_01627 1.07e-39 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
LEOBILOC_01628 4.9e-158 - - - L ko:K07459 - ko00000 DNA synthesis involved in DNA repair
LEOBILOC_01629 2.81e-167 - 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase activity
LEOBILOC_01630 3.45e-72 - - - L - - - Recombinase
LEOBILOC_01631 6.69e-110 - - - L - - - RNA-directed DNA polymerase (reverse transcriptase)
LEOBILOC_01632 1.16e-285 mvaS 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
LEOBILOC_01633 5.19e-174 - - - L - - - PFAM Transposase, Mutator
LEOBILOC_01634 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
LEOBILOC_01635 0.0 lysP - - E ko:K11733 - ko00000,ko02000 amino acid
LEOBILOC_01636 1.28e-148 ycfA - - K - - - Transcriptional regulator
LEOBILOC_01637 2.16e-267 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
LEOBILOC_01639 3.39e-167 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
LEOBILOC_01640 9.11e-92 - - - S - - - Hemerythrin HHE cation binding domain
LEOBILOC_01641 6.9e-69 - - - - - - - -
LEOBILOC_01642 5.19e-59 - - - - - - - -
LEOBILOC_01643 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LEOBILOC_01644 0.0 - 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
LEOBILOC_01645 2.17e-128 - - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase molybdenum cofactor assembly chaperone
LEOBILOC_01646 7.42e-162 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 nitrate reductase, gamma subunit
LEOBILOC_01647 7.53e-263 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
LEOBILOC_01648 1.07e-207 fda 4.1.2.13 - G ko:K01623 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147 Belongs to the class I fructose-bisphosphate aldolase family
LEOBILOC_01649 3.71e-250 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
LEOBILOC_01650 9.87e-27 - - - M - - - COG3209 Rhs family protein
LEOBILOC_01651 1.19e-121 - - - M - - - SIS domain
LEOBILOC_01652 1.01e-41 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
LEOBILOC_01653 7.09e-54 - - - S - - - HAD hydrolase, family IA, variant 3
LEOBILOC_01654 9.65e-186 - - - M - - - SIS domain
LEOBILOC_01655 4.02e-76 - - - G - - - PTS system sorbose subfamily IIB component
LEOBILOC_01656 7.03e-127 - - - G - - - PTS system mannose/fructose/sorbose family IID component
LEOBILOC_01657 2.92e-87 - - - G - - - PTS system sorbose-specific iic component
LEOBILOC_01658 3.06e-81 - - - K - - - UTRA domain
LEOBILOC_01659 2.84e-35 - - - K - - - UTRA
LEOBILOC_01660 2.65e-289 - 2.3.1.179 - IQ ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Beta-ketoacyl synthase, C-terminal domain
LEOBILOC_01661 1.78e-42 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
LEOBILOC_01662 1.32e-28 - - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix gluconate operon transcriptional repressor
LEOBILOC_01663 2.05e-231 - - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
LEOBILOC_01664 0.0 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
LEOBILOC_01665 0.0 estB - - V - - - Belongs to the UPF0214 family
LEOBILOC_01666 2.7e-295 ybbC - - S - - - protein conserved in bacteria
LEOBILOC_01667 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LEOBILOC_01668 0.0 yfiB - - V ko:K06147 - ko00000,ko02000 ABC transporter
LEOBILOC_01669 6.95e-105 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LEOBILOC_01670 1.05e-133 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LEOBILOC_01672 6.41e-157 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
LEOBILOC_01673 1.34e-195 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
LEOBILOC_01674 7.1e-194 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
LEOBILOC_01675 6.32e-263 iolT - - U ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LEOBILOC_01676 4.38e-180 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
LEOBILOC_01677 1.5e-142 - - - S - - - Oxidoreductase
LEOBILOC_01678 3.93e-29 yxlH - - EGP - - - Major Facilitator Superfamily
LEOBILOC_01679 1.38e-165 iolJ 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
LEOBILOC_01680 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
LEOBILOC_01681 7.28e-185 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
LEOBILOC_01682 1.05e-167 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
LEOBILOC_01683 4.48e-314 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEOBILOC_01684 4.75e-147 cwlS - CBM50 M ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LEOBILOC_01686 6.67e-134 - - - P - - - Integral membrane protein TerC family
LEOBILOC_01687 2.01e-195 XK27_04815 - - S ko:K07088 - ko00000 Membrane transport protein
LEOBILOC_01688 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LEOBILOC_01689 2.65e-32 - - - S - - - Uncharacterized small protein (DUF2292)
LEOBILOC_01690 4.47e-121 ssuE 1.5.1.38 - S ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 ko00000,ko00001,ko01000 FMN reductase
LEOBILOC_01691 2.39e-176 ssuB - - P ko:K02049,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
LEOBILOC_01692 5.63e-176 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LEOBILOC_01693 8.66e-277 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
LEOBILOC_01694 6.76e-206 - - - P ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LEOBILOC_01695 1.52e-238 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LEOBILOC_01696 5.31e-05 - - - - - - - -
LEOBILOC_01697 3.69e-111 - - - S - - - SMI1-KNR4 cell-wall
LEOBILOC_01698 7.37e-60 - - - S - - - Protein of unknown function (DUF3969)
LEOBILOC_01700 6.38e-97 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
LEOBILOC_01701 1.34e-132 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
LEOBILOC_01702 7.06e-249 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
LEOBILOC_01703 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
LEOBILOC_01704 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LEOBILOC_01705 8.64e-253 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
LEOBILOC_01706 1.01e-156 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
LEOBILOC_01707 2.39e-108 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
LEOBILOC_01708 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LEOBILOC_01709 3.55e-155 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
LEOBILOC_01710 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LEOBILOC_01711 1.71e-91 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LEOBILOC_01712 4.29e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEOBILOC_01713 5.27e-117 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
LEOBILOC_01714 1.56e-146 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
LEOBILOC_01716 6.36e-34 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LEOBILOC_01717 9.8e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
LEOBILOC_01718 2.39e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LEOBILOC_01719 6.58e-161 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LEOBILOC_01721 5.97e-106 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LEOBILOC_01722 1.94e-69 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LEOBILOC_01723 1.26e-144 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
LEOBILOC_01724 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEOBILOC_01725 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEOBILOC_01726 5.27e-49 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
LEOBILOC_01727 2.06e-93 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LEOBILOC_01728 1.19e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LEOBILOC_01729 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LEOBILOC_01730 8.83e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LEOBILOC_01731 3.63e-95 - - - S - - - Protein of unknown function (DUF2961)
LEOBILOC_01732 0.0 - - - - - - - -
LEOBILOC_01733 2.91e-277 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Major facilitator superfamily
LEOBILOC_01734 0.0 yheS_2 - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
LEOBILOC_01735 8.45e-60 - - - S - - - Nucleotidyltransferase domain
LEOBILOC_01736 8.06e-219 - - - E - - - Conserved region in glutamate synthase
LEOBILOC_01737 9.74e-139 - - - K - - - TipAS antibiotic-recognition domain
LEOBILOC_01738 5.38e-309 - - - L ko:K07486 - ko00000 COG3547 Transposase and inactivated derivatives
LEOBILOC_01739 1.28e-55 - - - K - - - transcriptional regulator
LEOBILOC_01740 1.74e-122 - - - K - - - TipAS antibiotic-recognition domain
LEOBILOC_01741 6.27e-240 - - - U - - - TIGRFAM drug resistance transporter, EmrB QacA subfamily
LEOBILOC_01742 3.98e-92 - - - K - - - PFAM GCN5-related N-acetyltransferase
LEOBILOC_01743 2.74e-90 - - - S - - - Nucleotidyltransferase domain
LEOBILOC_01744 5.51e-159 vatD 2.3.1.79 - S ko:K00661,ko:K18234 - ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
LEOBILOC_01745 2.51e-212 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
LEOBILOC_01746 2.76e-33 - - - S - - - Rifampin ADP-ribosyl transferase
LEOBILOC_01747 1.1e-131 - - - S - - - Rifampin ADP-ribosyl transferase
LEOBILOC_01748 9.91e-14 - - - L - - - PFAM transposase, IS4 family protein
LEOBILOC_01749 9.42e-27 - - - - - - - -
LEOBILOC_01750 3.21e-53 - - - L - - - PFAM Transposase, IS4-like
LEOBILOC_01751 2.59e-79 - - - L - - - PFAM Transposase, IS4-like
LEOBILOC_01752 1.38e-97 ywoH - - K - - - transcriptional
LEOBILOC_01753 6.02e-270 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LEOBILOC_01754 2.3e-229 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LEOBILOC_01755 0.0 - 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
LEOBILOC_01756 1.41e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LEOBILOC_01757 6.78e-218 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LEOBILOC_01758 5.03e-148 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LEOBILOC_01759 2.46e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LEOBILOC_01760 8.34e-127 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
LEOBILOC_01761 1.27e-128 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
LEOBILOC_01762 5.43e-172 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LEOBILOC_01763 7.76e-193 thiD 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
LEOBILOC_01764 3.72e-80 yojF - - S - - - Protein of unknown function (DUF1806)
LEOBILOC_01765 1.15e-167 bshB2 - - S ko:K22135 - ko00000,ko01000 deacetylase
LEOBILOC_01766 3.74e-208 ycsE - - S - - - hydrolases of the HAD superfamily
LEOBILOC_01767 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
LEOBILOC_01768 3.97e-294 phoA 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
LEOBILOC_01769 1.29e-196 murR - - K - - - Transcriptional regulator
LEOBILOC_01770 5.96e-205 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LEOBILOC_01771 1.73e-19 - - - - - - - -
LEOBILOC_01772 7.86e-97 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LEOBILOC_01774 1.43e-152 ywbG - - M - - - effector of murein hydrolase
LEOBILOC_01775 4.35e-77 ywbH - - S ko:K06518 - ko00000,ko02000 LrgA family
LEOBILOC_01776 3.16e-233 ywbI - - K - - - Transcriptional regulator
LEOBILOC_01777 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LEOBILOC_01778 1.64e-206 - - - S - - - Protein of unknown function (DUF1646)
LEOBILOC_01779 8.16e-93 - - - S - - - Threonine/Serine exporter, ThrE
LEOBILOC_01780 1.13e-169 yjjP - - S - - - Putative threonine/serine exporter
LEOBILOC_01781 6.69e-264 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LEOBILOC_01782 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
LEOBILOC_01783 2.89e-162 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
LEOBILOC_01784 0.0 lytS 2.7.13.3 - T ko:K02478,ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LEOBILOC_01785 2.23e-196 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LEOBILOC_01786 1.74e-145 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
LEOBILOC_01787 9.71e-244 metN_1 - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LEOBILOC_01788 6.34e-181 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
LEOBILOC_01789 2.55e-130 - - - - - - - -
LEOBILOC_01790 3.18e-282 - - - NU ko:K18640 - ko00000,ko04812 Pilus assembly protein
LEOBILOC_01791 2.03e-307 yisQ - - V - - - Mate efflux family protein
LEOBILOC_01792 5.29e-196 gspA - - M - - - Glycosyl transferase family 8
LEOBILOC_01793 1.24e-300 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
LEOBILOC_01794 0.0 - - - EGP - - - the major facilitator superfamily
LEOBILOC_01795 1.79e-287 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
LEOBILOC_01796 0.0 poxB 1.2.5.1 - EH ko:K00156 ko00620,map00620 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LEOBILOC_01797 3.67e-163 - 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LEOBILOC_01798 0.0 - 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
LEOBILOC_01799 3.01e-145 yhhQ_2 - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LEOBILOC_01800 9.24e-128 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LEOBILOC_01801 0.0 - - - S ko:K06994,ko:K07003 - ko00000 MMPL domain protein
LEOBILOC_01802 0.0 amy 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
LEOBILOC_01803 2.14e-52 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
LEOBILOC_01804 7.01e-186 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LEOBILOC_01805 5.27e-305 LYS1 1.5.1.7 - E ko:K00290 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Saccharopine dehydrogenase
LEOBILOC_01806 3.71e-286 nspC 4.1.1.96 - E ko:K13747 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase, C-terminal sheet domain
LEOBILOC_01807 7.85e-41 - - - S - - - PD-(D/E)XK nuclease family transposase
LEOBILOC_01808 7.23e-264 - - - S - - - Domain of unknown function (DUF1611_N) Rossmann-like domain
LEOBILOC_01809 5.86e-275 - - - E - - - Alanine racemase, N-terminal domain
LEOBILOC_01810 1.96e-190 peb1A - - ET ko:K02030,ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LEOBILOC_01811 9.3e-167 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
LEOBILOC_01812 3.93e-151 glnP7 - - E ko:K02029 - ko00000,ko00002,ko02000 amino acid ABC transporter
LEOBILOC_01813 2.91e-148 glnP9 - - E ko:K02029 - ko00000,ko00002,ko02000 amino acid ABC transporter
LEOBILOC_01814 0.0 mqo 1.1.5.4 - S ko:K00116 ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 malate quinone oxidoreductase
LEOBILOC_01815 1.48e-306 kgtP - - EGP ko:K03761 - ko00000,ko02000 -transporter
LEOBILOC_01816 3.83e-79 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
LEOBILOC_01817 3.47e-52 - - - S - - - Protein of unknown function (DUF1048)
LEOBILOC_01818 5.05e-70 - - - S - - - Protein of unknown function (DUF1048)
LEOBILOC_01819 5.21e-62 - - - S - - - Protein of unknown function (DUF1048)
LEOBILOC_01821 1.48e-98 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LEOBILOC_01822 1.17e-273 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LEOBILOC_01823 7.14e-185 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
LEOBILOC_01824 5.87e-182 yycI - - S - - - protein conserved in bacteria
LEOBILOC_01825 9.73e-317 yycH - - S - - - protein conserved in bacteria
LEOBILOC_01826 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LEOBILOC_01827 5.26e-173 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEOBILOC_01830 1.94e-316 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LEOBILOC_01831 1.84e-316 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
LEOBILOC_01832 9.21e-94 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
LEOBILOC_01833 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
LEOBILOC_01834 3.77e-200 yybS - - S - - - membrane
LEOBILOC_01835 7.33e-50 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LEOBILOC_01836 2.87e-112 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LEOBILOC_01837 3.01e-63 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
LEOBILOC_01838 3.83e-104 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LEOBILOC_01839 8.48e-285 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LEOBILOC_01840 2.6e-149 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
LEOBILOC_01841 2.86e-267 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LEOBILOC_01842 1.51e-260 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LEOBILOC_01843 3.73e-44 yyzM - - S - - - protein conserved in bacteria
LEOBILOC_01844 2.94e-208 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
LEOBILOC_01845 1.52e-144 yyaC - - S - - - Sporulation protein YyaC
LEOBILOC_01846 1.07e-151 ydfK - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
LEOBILOC_01847 3.25e-192 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LEOBILOC_01848 3.38e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
LEOBILOC_01849 2.69e-195 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
LEOBILOC_01850 3.04e-173 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
LEOBILOC_01851 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LEOBILOC_01852 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LEOBILOC_01853 2.94e-142 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
LEOBILOC_01854 5.78e-174 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEOBILOC_01855 7.56e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LEOBILOC_01856 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LEOBILOC_01857 4.36e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LEOBILOC_01858 4.01e-44 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
LEOBILOC_01859 1.77e-261 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LEOBILOC_01860 9.35e-16 yaaB - - S - - - Domain of unknown function (DUF370)
LEOBILOC_01861 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEOBILOC_01862 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEOBILOC_01863 4.81e-252 M1-161 - - T - - - HD domain
LEOBILOC_01873 1.27e-216 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
LEOBILOC_01875 6.53e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LEOBILOC_01876 3.34e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
LEOBILOC_01877 6.33e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LEOBILOC_01878 2.16e-283 ybbR - - S - - - protein conserved in bacteria
LEOBILOC_01879 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LEOBILOC_01880 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LEOBILOC_01882 1.91e-123 M1-431 - - S - - - Protein of unknown function (DUF1706)
LEOBILOC_01883 3.43e-185 - 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
LEOBILOC_01884 1.16e-80 - - - - - - - -
LEOBILOC_01885 6.46e-150 - - - E - - - lactoylglutathione lyase activity
LEOBILOC_01886 6.64e-297 lmrP - - E ko:K08152 - ko00000,ko02000 Transmembrane secretion effector
LEOBILOC_01887 1.32e-97 yycN - - K - - - FR47-like protein
LEOBILOC_01888 1.16e-169 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
LEOBILOC_01889 1.6e-163 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
LEOBILOC_01890 4.01e-58 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
LEOBILOC_01891 1.33e-148 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
LEOBILOC_01892 5.53e-296 mvaA 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Hydroxymethylglutaryl-coenzyme A reductase
LEOBILOC_01893 3.53e-31 - - - - - - - -
LEOBILOC_01894 4.49e-82 XK27_01125 - - L ko:K07484 - ko00000 IS66 Orf2 like protein
LEOBILOC_01895 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
LEOBILOC_01897 3.09e-15 - - - L - - - Transposase, IS4 family protein
LEOBILOC_01898 2.1e-26 ybxH - - S - - - Family of unknown function (DUF5370)
LEOBILOC_01899 1.25e-241 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
LEOBILOC_01900 3.83e-179 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LEOBILOC_01901 8.46e-242 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEOBILOC_01902 1.31e-121 - - - - - - - -
LEOBILOC_01904 8.22e-185 - - - P - - - Major facilitator superfamily
LEOBILOC_01905 1.16e-75 - - - EGP - - - Major facilitator Superfamily
LEOBILOC_01906 3.36e-38 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
LEOBILOC_01907 9.48e-43 - - - - - - - -
LEOBILOC_01908 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
LEOBILOC_01909 4.84e-114 yrhD - - S - - - Protein of unknown function (DUF1641)
LEOBILOC_01910 4.24e-248 - 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LEOBILOC_01911 1.01e-111 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LEOBILOC_01912 1.45e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LEOBILOC_01913 1.16e-102 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
LEOBILOC_01914 1.55e-114 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
LEOBILOC_01915 2.53e-303 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
LEOBILOC_01916 6.85e-155 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
LEOBILOC_01917 7.87e-111 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
LEOBILOC_01918 4.89e-238 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LEOBILOC_01919 1.1e-166 - 3.6.3.29 - P ko:K02017 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
LEOBILOC_01920 2.56e-132 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
LEOBILOC_01921 6.69e-166 - - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Molybdenum ABC transporter
LEOBILOC_01922 4.16e-202 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Major Facilitator Superfamily
LEOBILOC_01923 1.82e-101 - - - S - - - YwiC-like protein
LEOBILOC_01924 1.01e-116 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 nitrate reductase, gamma subunit
LEOBILOC_01925 7.95e-61 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 Nitrate reductase delta subunit
LEOBILOC_01926 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
LEOBILOC_01927 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Molybdopterin oxidoreductase Fe4S4 domain
LEOBILOC_01928 2.83e-128 fnr_1 - - K - - - helix_turn_helix, cAMP Regulatory protein
LEOBILOC_01929 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LEOBILOC_01930 1.16e-154 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
LEOBILOC_01931 4.88e-154 acuB - - S ko:K04767 - ko00000 Acetoin utilization protein AcuB
LEOBILOC_01932 9.26e-296 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
LEOBILOC_01933 2.93e-234 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
LEOBILOC_01934 3.79e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
LEOBILOC_01935 1.51e-52 ytxH - - S - - - COG4980 Gas vesicle protein
LEOBILOC_01936 7.74e-84 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LEOBILOC_01937 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
LEOBILOC_01938 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LEOBILOC_01939 9.16e-128 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LEOBILOC_01940 2.17e-141 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEOBILOC_01941 3.69e-187 ytpQ - - S - - - Belongs to the UPF0354 family
LEOBILOC_01942 1.42e-72 ytpP - - CO - - - Thioredoxin
LEOBILOC_01943 3.48e-268 rsbU 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
LEOBILOC_01944 3.71e-199 - 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 chemotaxis
LEOBILOC_01945 0.0 - 2.7.13.3 - T ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 Histidine kinase
LEOBILOC_01946 5.39e-243 - - - EGP - - - Transmembrane secretion effector
LEOBILOC_01948 1.13e-93 - - - - - - - -
LEOBILOC_01949 7.2e-120 yjjX - - F - - - Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LEOBILOC_01950 3.18e-262 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
LEOBILOC_01951 2.11e-69 ytzB - - S - - - small secreted protein
LEOBILOC_01952 7.93e-217 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LEOBILOC_01954 5.27e-170 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LEOBILOC_01955 5.63e-77 ytzH - - S - - - YtzH-like protein
LEOBILOC_01956 1.3e-200 ytmP - - M - - - Phosphotransferase
LEOBILOC_01957 2.43e-197 ytlQ - - - - - - -
LEOBILOC_01958 4.8e-139 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LEOBILOC_01960 4.89e-204 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
LEOBILOC_01961 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
LEOBILOC_01962 9e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
LEOBILOC_01963 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEOBILOC_01964 9.36e-36 yteV - - S - - - Sporulation protein Cse60
LEOBILOC_01967 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
LEOBILOC_01968 1.85e-239 yttB - - EGP - - - Major facilitator superfamily
LEOBILOC_01969 4.76e-56 ytzC - - S - - - Protein of unknown function (DUF2524)
LEOBILOC_01970 1.37e-134 ytqB - - J - - - Putative rRNA methylase
LEOBILOC_01972 2.36e-272 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
LEOBILOC_01973 5.29e-198 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
LEOBILOC_01974 1.29e-107 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LEOBILOC_01975 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LEOBILOC_01976 1.85e-282 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LEOBILOC_01977 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LEOBILOC_01978 1.28e-89 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LEOBILOC_01979 1.11e-251 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
LEOBILOC_01980 4.85e-130 ywqN - - S - - - NAD(P)H-dependent
LEOBILOC_01981 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
LEOBILOC_01983 9.48e-108 - 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LEOBILOC_01985 1.88e-273 - - - S - - - Psort location CytoplasmicMembrane, score
LEOBILOC_01986 4.18e-155 - - - K - - - Bacterial regulatory proteins, tetR family
LEOBILOC_01987 2.77e-290 yfiS - - EGP - - - Major facilitator superfamily
LEOBILOC_01988 1.04e-172 ssuC - - P ko:K15599 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 binding-protein-dependent transport systems inner membrane component
LEOBILOC_01989 7.23e-238 - - - P ko:K02051,ko:K15598 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
LEOBILOC_01991 1.48e-94 - - - S ko:K06991 - ko00000 Glyoxalase bleomycin resistance protein dioxygenase
LEOBILOC_01992 2.23e-191 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
LEOBILOC_01993 1.42e-170 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
LEOBILOC_01994 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LEOBILOC_01995 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
LEOBILOC_01996 1.31e-141 - - - - - - - -
LEOBILOC_01997 4.29e-173 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
LEOBILOC_01998 0.0 dapE - - E - - - Peptidase dimerisation domain
LEOBILOC_01999 4.26e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
LEOBILOC_02000 8.15e-240 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LEOBILOC_02001 2.26e-243 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LEOBILOC_02002 2.8e-277 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LEOBILOC_02003 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LEOBILOC_02004 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
LEOBILOC_02005 1e-246 - - - M ko:K05802,ko:K22051 - ko00000,ko02000 Mechanosensitive ion channel
LEOBILOC_02006 2.64e-246 - - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LEOBILOC_02007 9.27e-75 - - - I - - - SCP-2 sterol transfer family
LEOBILOC_02009 1.95e-221 - 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
LEOBILOC_02011 8.28e-135 ymdB - - S - - - Appr-1'-p processing enzyme
LEOBILOC_02012 1.65e-35 sspH - - S ko:K06425 - ko00000 small acid-soluble spore protein
LEOBILOC_02013 5.17e-175 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LEOBILOC_02014 1.12e-266 - 2.3.1.16, 2.3.1.9 - I ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
LEOBILOC_02015 0.0 - 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LEOBILOC_02016 8.13e-82 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
LEOBILOC_02017 9.84e-192 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
LEOBILOC_02018 2.03e-125 yozB - - S ko:K08976 - ko00000 membrane
LEOBILOC_02019 1.83e-79 - - - - - - - -
LEOBILOC_02020 3.38e-104 - - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LEOBILOC_02021 2.57e-229 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
LEOBILOC_02022 3.5e-168 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LEOBILOC_02023 3.14e-275 - - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LEOBILOC_02024 5.22e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
LEOBILOC_02025 1.99e-189 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
LEOBILOC_02026 1.7e-200 - 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
LEOBILOC_02027 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
LEOBILOC_02028 5.86e-255 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
LEOBILOC_02029 3.81e-275 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LEOBILOC_02030 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LEOBILOC_02031 5.37e-250 - - - G ko:K07190 ko04020,ko04910,ko04922,map04020,map04910,map04922 ko00000,ko00001 Glycosyl hydrolases family 15
LEOBILOC_02032 1.19e-31 - - - S - - - YpzG-like protein
LEOBILOC_02033 5.98e-116 - - - Q - - - protein disulfide oxidoreductase activity
LEOBILOC_02034 4.96e-123 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
LEOBILOC_02035 3.46e-155 XK27_06885 - - L - - - COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LEOBILOC_02036 5.39e-291 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LEOBILOC_02037 1.03e-100 - - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
LEOBILOC_02038 2.41e-106 - - - V - - - VanZ like family
LEOBILOC_02039 4.69e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LEOBILOC_02040 8.18e-215 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LEOBILOC_02041 1.54e-73 - - - - - - - -
LEOBILOC_02042 5.78e-215 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
LEOBILOC_02043 3.33e-118 - - - S - - - Protein of unknown function (DUF1189)
LEOBILOC_02044 5.09e-51 - - - S - - - Protein of unknown function (DUF1450)
LEOBILOC_02045 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LEOBILOC_02046 3.34e-92 - - - I - - - MaoC like domain
LEOBILOC_02047 1.31e-103 - - - I - - - N-terminal half of MaoC dehydratase
LEOBILOC_02048 1.12e-172 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
LEOBILOC_02049 0.0 dld 1.1.2.4 - C ko:K00102 ko00620,map00620 ko00000,ko00001,ko01000 Glycolate oxidase subunit
LEOBILOC_02051 1.97e-256 selU - - S ko:K06917 - ko00000,ko01000,ko03016 tRNA 2-selenouridine synthase
LEOBILOC_02052 1.27e-248 selD 2.7.9.3 - E ko:K01008 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000,ko03016 Synthesizes selenophosphate from selenide and ATP
LEOBILOC_02053 3.42e-175 - - - T - - - Calcineurin-like phosphoesterase superfamily domain
LEOBILOC_02054 4.41e-247 - - - S ko:K07089 - ko00000 Predicted permease
LEOBILOC_02055 8.66e-294 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LEOBILOC_02056 2.06e-257 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LEOBILOC_02057 1.52e-93 yjlC - - S - - - Protein of unknown function (DUF1641)
LEOBILOC_02058 2.59e-277 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LEOBILOC_02059 2.57e-294 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
LEOBILOC_02060 1.44e-157 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LEOBILOC_02061 2.55e-166 yvpB - - NU - - - protein conserved in bacteria
LEOBILOC_02062 2.53e-67 tnrA - - K - - - transcriptional
LEOBILOC_02063 3.93e-140 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LEOBILOC_02064 3.77e-32 - - - S - - - Virus attachment protein p12 family
LEOBILOC_02065 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
LEOBILOC_02066 1.97e-63 - - - P ko:K04758 - ko00000,ko02000 COG1918 Fe2 transport system protein A
LEOBILOC_02067 8.52e-288 - 2.6.1.83 - E ko:K10206 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LEOBILOC_02068 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
LEOBILOC_02069 2.21e-295 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
LEOBILOC_02070 2.58e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LEOBILOC_02071 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
LEOBILOC_02072 1.3e-266 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LEOBILOC_02073 4.74e-287 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
LEOBILOC_02074 3.96e-181 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
LEOBILOC_02075 3.04e-297 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LEOBILOC_02076 2.12e-254 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LEOBILOC_02078 3.71e-105 - - - - - - - -
LEOBILOC_02079 2.71e-194 yjqC - - P ko:K07217 - ko00000 Catalase
LEOBILOC_02080 5.68e-110 - - - - - - - -
LEOBILOC_02081 2.54e-42 - - - K ko:K03704 - ko00000,ko03000 Cold shock
LEOBILOC_02083 6.06e-222 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
LEOBILOC_02084 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
LEOBILOC_02085 6.76e-137 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LEOBILOC_02086 3.59e-97 yneK - - S - - - Protein of unknown function (DUF2621)
LEOBILOC_02087 1.09e-100 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
LEOBILOC_02088 1.96e-77 yneI - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
LEOBILOC_02089 1.01e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
LEOBILOC_02090 1.25e-38 yneF - - S ko:K09976 - ko00000 UPF0154 protein
LEOBILOC_02091 2.67e-101 yneE - - S - - - Sporulation inhibitor of replication protein sirA
LEOBILOC_02092 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LEOBILOC_02093 5.7e-44 ynzC - - S - - - UPF0291 protein
LEOBILOC_02094 1.18e-268 - - - L - - - Transposase
LEOBILOC_02096 4.8e-144 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
LEOBILOC_02097 2.24e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
LEOBILOC_02098 7.11e-293 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LEOBILOC_02099 1.74e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
LEOBILOC_02100 1.79e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEOBILOC_02101 3.7e-149 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LEOBILOC_02102 2.24e-203 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
LEOBILOC_02103 2.03e-80 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 response regulator
LEOBILOC_02104 5.78e-268 - - - - - - - -
LEOBILOC_02105 1.56e-190 - - - - - - - -
LEOBILOC_02106 2.05e-162 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LEOBILOC_02107 8.23e-88 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
LEOBILOC_02108 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LEOBILOC_02109 9.54e-89 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LEOBILOC_02110 6.37e-160 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LEOBILOC_02111 0.0 - - - S ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
LEOBILOC_02112 0.0 icmF 5.4.99.13 - EI ko:K11942 - ko00000,ko01000 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LEOBILOC_02113 4.33e-146 kstR2_2 - - K - - - Transcriptional regulator
LEOBILOC_02114 1.6e-269 acdA 1.3.8.1, 1.3.8.7 - I ko:K00248,ko:K00249 ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320 ko00000,ko00001,ko00002,ko01000 acyl-CoA dehydrogenase
LEOBILOC_02115 6.5e-268 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
LEOBILOC_02116 9.36e-275 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
LEOBILOC_02118 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
LEOBILOC_02119 2.05e-277 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
LEOBILOC_02120 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
LEOBILOC_02121 3.16e-95 ywiB - - S - - - Domain of unknown function (DUF1934)
LEOBILOC_02122 6.02e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
LEOBILOC_02123 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LEOBILOC_02124 5.31e-120 ywhD - - S - - - YwhD family
LEOBILOC_02125 3.55e-154 ywhC - - S - - - Peptidase M50
LEOBILOC_02126 1.33e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
LEOBILOC_02127 4.88e-117 ywgA - - - ko:K09388 - ko00000 -
LEOBILOC_02128 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
LEOBILOC_02129 6.46e-138 rsfA - - S ko:K06314 - ko00000,ko03000 Transcriptional regulator
LEOBILOC_02130 4.33e-197 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
LEOBILOC_02131 3.11e-225 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
LEOBILOC_02132 4.51e-186 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
LEOBILOC_02133 1.26e-105 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
LEOBILOC_02134 1.86e-77 ywdK - - S - - - small membrane protein
LEOBILOC_02135 1.53e-46 - - - S - - - Family of unknown function (DUF5327)
LEOBILOC_02136 1.57e-170 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LEOBILOC_02137 3.07e-70 - - - S - - - Heat induced stress protein YflT
LEOBILOC_02138 3.71e-05 - - - K - - - Helix-turn-helix XRE-family like proteins
LEOBILOC_02139 1.75e-198 - - - L - - - Archaeal putative transposase ISC1217
LEOBILOC_02140 1.74e-26 - - - S - - - Circ_ocin_uber circular bacteriocin, circularin A uberolysin family protein
LEOBILOC_02141 0.0 - - - - - - - -
LEOBILOC_02142 1.38e-54 - - - S - - - Stage II sporulation protein M
LEOBILOC_02143 4.36e-155 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LEOBILOC_02146 1.18e-41 - - - - - - - -
LEOBILOC_02147 0.0 ppc 4.1.1.31 - C ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LEOBILOC_02149 3.52e-225 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LEOBILOC_02150 9.63e-157 yabE - - S ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 3D domain
LEOBILOC_02151 1.09e-127 - - - KT - - - HD domain
LEOBILOC_02152 0.0 pip - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
LEOBILOC_02153 2.13e-64 yqgV - - S - - - Thiamine-binding protein
LEOBILOC_02154 7.09e-251 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
LEOBILOC_02155 0.0 - - - S - - - ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LEOBILOC_02156 0.0 levR - - K - - - PTS system fructose IIA component
LEOBILOC_02157 4.91e-110 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
LEOBILOC_02158 9.73e-228 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
LEOBILOC_02159 3.45e-174 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
LEOBILOC_02160 1.04e-217 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
LEOBILOC_02161 2.74e-84 manO - - S - - - Domain of unknown function (DUF956)
LEOBILOC_02162 1.13e-270 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LEOBILOC_02163 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
LEOBILOC_02164 5.75e-213 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LEOBILOC_02165 6.59e-106 - - - S - - - Heat induced stress protein YflT
LEOBILOC_02166 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
LEOBILOC_02168 1.4e-154 - - - S - - - Thiamine-binding protein
LEOBILOC_02169 8.33e-183 - - - P ko:K15599 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 binding-protein-dependent transport systems inner membrane component
LEOBILOC_02170 1.47e-243 M1-596 - - P ko:K02051,ko:K15598 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
LEOBILOC_02171 3.42e-180 - - - P ko:K02049,ko:K15600 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LEOBILOC_02172 1.47e-214 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LEOBILOC_02173 9.28e-249 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LEOBILOC_02174 4.26e-309 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
LEOBILOC_02175 1.84e-189 - - - E - - - Belongs to the arginase family
LEOBILOC_02176 1.46e-30 - - - E - - - Belongs to the arginase family
LEOBILOC_02177 1.09e-22 - - - S - - - Protein of unknown function (DUF4064)
LEOBILOC_02178 0.0 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LEOBILOC_02179 3.21e-212 - 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LEOBILOC_02180 6.01e-63 - - - S - - - Sodium pantothenate symporter
LEOBILOC_02181 1.75e-312 panF - - H ko:K14392 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEOBILOC_02184 6.77e-219 corA - - P ko:K03284 - ko00000,ko02000 Mg2 transporter protein CorA family protein
LEOBILOC_02185 0.0 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
LEOBILOC_02187 1.66e-269 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
LEOBILOC_02188 2.82e-111 - - - - - - - -
LEOBILOC_02189 1.08e-101 - - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LEOBILOC_02190 8.39e-180 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
LEOBILOC_02192 9.2e-130 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
LEOBILOC_02193 1.76e-82 - - - K - - - transcriptional
LEOBILOC_02194 0.0 - 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LEOBILOC_02195 0.0 - - - I - - - Acyl-CoA dehydrogenase, middle domain
LEOBILOC_02196 5.86e-173 - - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEOBILOC_02197 2.96e-203 yokD 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 aminoglycoside
LEOBILOC_02198 5.71e-299 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEOBILOC_02199 1.09e-292 - - - L - - - PFAM Transposase, IS116 IS110 IS902
LEOBILOC_02200 9.86e-71 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
LEOBILOC_02201 1.1e-115 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LEOBILOC_02203 3e-24 - - - S - - - CAAX protease self-immunity
LEOBILOC_02204 2.87e-223 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
LEOBILOC_02205 2.15e-204 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LEOBILOC_02206 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
LEOBILOC_02208 0.0 - 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LEOBILOC_02209 1.08e-111 - - - - - - - -
LEOBILOC_02210 1.23e-188 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LEOBILOC_02211 4.8e-170 ycdF 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Short-chain dehydrogenase reductase sdr
LEOBILOC_02212 6.37e-42 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
LEOBILOC_02213 6.98e-143 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
LEOBILOC_02214 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LEOBILOC_02215 2.15e-208 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
LEOBILOC_02216 4.17e-157 yhcW - - S ko:K07025 - ko00000 hydrolase
LEOBILOC_02217 1.59e-212 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
LEOBILOC_02218 5.85e-24 macB1 - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
LEOBILOC_02219 6.44e-49 csfB - - S - - - Inhibitor of sigma-G Gin
LEOBILOC_02220 1.43e-30 - - - S - - - Zinc-ribbon containing domain
LEOBILOC_02221 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
LEOBILOC_02222 2.66e-157 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
LEOBILOC_02223 9.59e-289 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LEOBILOC_02224 6.79e-79 - - - - - - - -
LEOBILOC_02227 7.6e-216 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
LEOBILOC_02228 2.41e-279 - - - EGP - - - Major facilitator superfamily
LEOBILOC_02229 3.67e-254 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
LEOBILOC_02230 3.26e-23 - - - S - - - YvrJ protein family
LEOBILOC_02231 8.05e-17 - - - S - - - Protein of unknown function (DUF2922)
LEOBILOC_02232 2.97e-12 - - - S - - - Protein of unknown function (DUF1659)
LEOBILOC_02233 0.0 wprA - - O ko:K13274,ko:K20276 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LEOBILOC_02234 1.16e-88 - - - S - - - Protein of unknown function (DUF2512)
LEOBILOC_02235 1.19e-66 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LEOBILOC_02236 4.19e-69 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LEOBILOC_02237 1.58e-106 - - - - - - - -
LEOBILOC_02238 9.22e-317 celD 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEOBILOC_02239 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LEOBILOC_02240 0.0 - - - K ko:K03491 - ko00000,ko03000 transcriptional regulator, MtlR
LEOBILOC_02241 1.4e-199 kdsA 2.5.1.55 - M ko:K01627 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the KdsA family
LEOBILOC_02242 9.27e-223 kdsD 5.3.1.13 - M ko:K06041 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the SIS family. GutQ KpsF subfamily
LEOBILOC_02243 2.97e-288 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LEOBILOC_02244 1.1e-277 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LEOBILOC_02246 0.0 treP 2.4.1.64 GH65 G ko:K05342 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
LEOBILOC_02247 2.21e-189 - - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LEOBILOC_02248 2.26e-277 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LEOBILOC_02249 7.8e-301 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
LEOBILOC_02250 2.38e-171 - - - K - - - helix_turn_helix, arabinose operon control protein
LEOBILOC_02251 2.41e-176 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LEOBILOC_02252 5.86e-31 - - - S - - - Iron-sulphur cluster biosynthesis
LEOBILOC_02253 3.4e-131 - - - S - - - PFAM Uncharacterised protein family UPF0236
LEOBILOC_02254 4.15e-192 - 3.1.1.5 - E ko:K10804 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 GDSL-like Lipase/Acylhydrolase
LEOBILOC_02255 9.08e-175 glx2 - - S - - - Metallo-beta-lactamase superfamily
LEOBILOC_02256 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
LEOBILOC_02257 3.77e-107 comM - - O ko:K07391 - ko00000 Mg chelatase subunit ChlI
LEOBILOC_02258 1.58e-43 - - - - - - - -
LEOBILOC_02259 0.0 - - - K - - - COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
LEOBILOC_02260 1.09e-250 - - - S ko:K09703 - ko00000 Protein of unknown function (DUF917)
LEOBILOC_02261 0.0 - - - EQ - - - Hydantoinase oxoprolinase
LEOBILOC_02262 1.74e-291 - - - F ko:K10974 - ko00000,ko02000 cytosine purines uracil thiamine allantoin
LEOBILOC_02263 1.92e-262 - - - S ko:K09703 - ko00000 Protein of unknown function (DUF917)
LEOBILOC_02264 0.0 apc3 - - EQ - - - Hydantoinase/oxoprolinase
LEOBILOC_02265 3.94e-225 - 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
LEOBILOC_02266 5.21e-86 - - - S - - - YjbR
LEOBILOC_02267 1.44e-83 - - - S - - - Protein of unknown function (DUF1648)
LEOBILOC_02268 1.69e-312 - - - L - - - Metallo-beta-lactamase superfamily
LEOBILOC_02269 4.6e-40 - - - S - - - Protein of unknown function (DUF3006)
LEOBILOC_02270 0.0 - - - L ko:K07012 - ko00000,ko01000,ko02048 Metal dependent phosphohydrolases with conserved 'HD' motif.
LEOBILOC_02271 1.1e-146 - - - S ko:K19119 - ko00000,ko02048 CRISPR-associated protein
LEOBILOC_02272 0.0 - - - S ko:K19117 - ko00000,ko02048 CRISPR-associated protein (Cas_Csd1)
LEOBILOC_02273 2.95e-210 - - - L ko:K19118 - ko00000,ko02048 CRISPR-associated protein Cas7
LEOBILOC_02275 3.89e-30 - - - - - - - -
LEOBILOC_02276 0.0 ybeC - - E - - - amino acid
LEOBILOC_02277 0.0 - - - O - - - cellulase activity
LEOBILOC_02278 1.38e-227 - - - K - - - cell envelope-related transcriptional attenuator
LEOBILOC_02279 4.78e-79 - - - - - - - -
LEOBILOC_02281 2.29e-222 ydhF - - S - - - Oxidoreductase
LEOBILOC_02282 5.91e-199 - - - S - - - transposase or invertase
LEOBILOC_02283 1.36e-12 - - - S - - - transposase or invertase
LEOBILOC_02284 2.94e-71 - - - S - - - Domain of unknown function (DUF3870)
LEOBILOC_02285 8.67e-297 - 1.3.99.32 - I ko:K16173 ko00362,ko01120,map00362,map01120 ko00000,ko00001,ko01000 Acyl-CoA dehydrogenase, N-terminal domain
LEOBILOC_02286 6.98e-286 - 2.8.3.19 - C ko:K18702 - ko00000,ko01000 acyl-CoA transferases carnitine dehydratase
LEOBILOC_02287 2.17e-243 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
LEOBILOC_02288 2.67e-273 - - - EGP - - - Major facilitator superfamily
LEOBILOC_02289 0.0 - - - K ko:K03491 - ko00000,ko03000 transcriptional regulator, MtlR
LEOBILOC_02290 5.21e-71 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LEOBILOC_02291 1.39e-70 ptcA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS cellobiose transporter subunit IIA
LEOBILOC_02292 2.62e-263 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
LEOBILOC_02293 1.89e-294 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEOBILOC_02294 5.8e-124 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 MFS/sugar transport protein
LEOBILOC_02295 1.34e-62 - - - L ko:K07496 - ko00000 Transposase
LEOBILOC_02296 1.73e-57 - - - S - - - COG NOG14552 non supervised orthologous group
LEOBILOC_02297 4.65e-56 - - - - - - - -
LEOBILOC_02298 4.27e-186 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PFAM Phosphotransferase system, mannose fructose sorbose family IID component
LEOBILOC_02299 1.59e-173 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
LEOBILOC_02300 2.02e-107 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
LEOBILOC_02301 9.99e-93 - - - G - - - PTS system fructose IIA component
LEOBILOC_02302 1.51e-138 - - - K ko:K19505 - ko00000,ko03000 PFAM sigma-54 factor interaction domain-containing protein
LEOBILOC_02303 0.0 - - - K ko:K19505 - ko00000,ko03000 PTS system fructose IIA component
LEOBILOC_02304 7.39e-56 - - - K ko:K19505 - ko00000,ko03000 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LEOBILOC_02305 7.04e-13 - - - L ko:K07494 - ko00000 DDE superfamily endonuclease
LEOBILOC_02307 1.05e-68 - - - Q - - - Isochorismatase family
LEOBILOC_02308 1.65e-122 - - - S - - - S4 RNA-binding domain
LEOBILOC_02309 1.63e-235 - - - - - - - -
LEOBILOC_02310 1.33e-66 yxjI - - S - - - LURP-one-related
LEOBILOC_02311 7.82e-204 yitS - - S - - - protein conserved in bacteria
LEOBILOC_02312 2.92e-34 - - - S - - - Protein of unknown function (DUF3813)
LEOBILOC_02313 1.16e-199 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
LEOBILOC_02314 1.14e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
LEOBILOC_02315 3.45e-37 yjzC - - S - - - YjzC-like protein
LEOBILOC_02316 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LEOBILOC_02317 4.87e-09 - - - S - - - Protein of unknown function (DUF2929)
LEOBILOC_02318 9.83e-186 - - - GM - - - ADP-glyceromanno-heptose 6-epimerase activity
LEOBILOC_02320 3.78e-220 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LEOBILOC_02321 5.3e-303 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LEOBILOC_02322 1.35e-193 yjaZ - - O - - - Zn-dependent protease
LEOBILOC_02323 2.97e-244 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LEOBILOC_02324 9e-226 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LEOBILOC_02325 1.85e-216 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEOBILOC_02326 5.05e-188 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 binding-protein-dependent transport systems inner membrane component
LEOBILOC_02327 0.0 oppA1 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
LEOBILOC_02328 5.46e-64 - - - S ko:K07077 - ko00000 FAD binding domain
LEOBILOC_02331 1.69e-198 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
LEOBILOC_02332 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LEOBILOC_02333 7.95e-111 - - - S ko:K21493 - ko00000,ko01000,ko02048 LXG domain of WXG superfamily
LEOBILOC_02334 4.74e-36 - - - S ko:K21493 - ko00000,ko01000,ko02048 LXG domain of WXG superfamily
LEOBILOC_02335 4.19e-240 - - - V ko:K19147 - ko00000,ko02048 McrBC 5-methylcytosine restriction system component
LEOBILOC_02336 0.0 - - - V ko:K07452 - ko00000,ko01000,ko02048 AAA domain (dynein-related subfamily)
LEOBILOC_02337 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
LEOBILOC_02338 1.16e-103 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
LEOBILOC_02339 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
LEOBILOC_02340 3.02e-36 - - - - - - - -
LEOBILOC_02341 6.91e-149 - - - E - - - LysE type translocator
LEOBILOC_02342 5.44e-109 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
LEOBILOC_02343 1.42e-102 crr - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
LEOBILOC_02344 0.0 - 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LEOBILOC_02345 0.0 - 2.7.1.199, 2.7.1.208 - G ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LEOBILOC_02346 2.66e-167 - - - K - - - Helix-turn-helix domain, rpiR family
LEOBILOC_02347 7.45e-144 mleP - - S ko:K07088 - ko00000 Membrane transport protein
LEOBILOC_02348 8.27e-25 mleP - - S ko:K07088 - ko00000 auxin efflux carrier
LEOBILOC_02349 0.0 sfcA 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
LEOBILOC_02350 2.62e-188 mleR - - K - - - LysR substrate binding domain
LEOBILOC_02351 3.91e-153 - - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEOBILOC_02352 1.05e-275 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEOBILOC_02353 5.87e-109 - 1.97.1.4 - O ko:K04068 - ko00000,ko01000 4Fe-4S single cluster domain
LEOBILOC_02354 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
LEOBILOC_02355 9.23e-247 - - - U - - - protein localization to endoplasmic reticulum
LEOBILOC_02356 5.3e-241 bdhA 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
LEOBILOC_02357 1.09e-88 - - - KT ko:K02647 - ko00000,ko03000 Sugar diacid utilization regulator
LEOBILOC_02358 2.24e-241 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
LEOBILOC_02359 2.09e-210 yojA - - EG ko:K03299 - ko00000,ko02000 Gluconate proton symporter
LEOBILOC_02360 4.5e-202 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
LEOBILOC_02361 3.34e-199 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LEOBILOC_02362 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
LEOBILOC_02363 3.65e-90 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LEOBILOC_02364 2.25e-207 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LEOBILOC_02365 1.26e-304 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
LEOBILOC_02366 4.93e-17 - - - S - - - transposase or invertase
LEOBILOC_02367 7.18e-206 - - - S - - - transposase or invertase
LEOBILOC_02369 2.7e-132 - - - S - - - Domain of unkown function (DUF1775)
LEOBILOC_02371 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
LEOBILOC_02373 9.85e-209 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LEOBILOC_02374 9.9e-153 - 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribulose-phosphate 3 epimerase family
LEOBILOC_02375 1.18e-228 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
LEOBILOC_02376 0.0 - - - G ko:K20114 ko02060,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
LEOBILOC_02377 1.04e-94 - - - G ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
LEOBILOC_02378 6.55e-86 - - - S - - - Putative restriction endonuclease
LEOBILOC_02379 8.42e-110 - - - - - - - -
LEOBILOC_02380 1.42e-55 - - - - - - - -
LEOBILOC_02381 1.83e-17 - - - S - - - Immunity protein Imm6
LEOBILOC_02382 3.3e-53 - - - L - - - PFAM Transposase, IS4-like
LEOBILOC_02383 0.0 - - - L - - - Transposase
LEOBILOC_02384 1.95e-293 mtlA 2.7.1.197 - G ko:K02798,ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LEOBILOC_02385 1.64e-201 mtlR - - K ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LEOBILOC_02386 1.78e-171 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 Mannitol dehydrogenase Rossmann domain
LEOBILOC_02387 2.77e-295 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LEOBILOC_02388 2.47e-138 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LEOBILOC_02389 6.35e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
LEOBILOC_02390 2.86e-315 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
LEOBILOC_02391 9.61e-246 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
LEOBILOC_02392 1.67e-172 - - - G - - - Xylose isomerase domain protein TIM barrel
LEOBILOC_02393 1.39e-230 - 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
LEOBILOC_02394 1.8e-307 - - - G ko:K03535 - ko00000,ko02000 Major Facilitator Superfamily
LEOBILOC_02395 1.33e-133 - 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
LEOBILOC_02396 1.27e-122 hxlB 5.3.1.27 - M ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
LEOBILOC_02398 4.58e-109 cotF - - M ko:K06329 - ko00000 Spore coat protein
LEOBILOC_02399 1.67e-222 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
LEOBILOC_02400 3.49e-127 - - - C - - - Nitroreductase family
LEOBILOC_02401 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
LEOBILOC_02402 4.59e-24 - - - - - - - -
LEOBILOC_02403 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
LEOBILOC_02404 8e-222 lysP - - E ko:K11733 - ko00000,ko02000 amino acid
LEOBILOC_02405 7.65e-273 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
LEOBILOC_02408 1.93e-243 cnpD2 - - T - - - HD domain
LEOBILOC_02409 0.0 glyQS 6.1.1.14 - J ko:K01880 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of glycine to tRNA(Gly)
LEOBILOC_02411 0.0 ydaO - - E - - - amino acid
LEOBILOC_02412 3.25e-188 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LEOBILOC_02413 1.83e-33 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LEOBILOC_02414 2.74e-223 ydbI - - S - - - AI-2E family transporter
LEOBILOC_02415 9.76e-172 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LEOBILOC_02416 2.08e-176 glnH - - ET ko:K02030,ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LEOBILOC_02417 1.04e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LEOBILOC_02418 1.53e-151 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LEOBILOC_02419 3.63e-91 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
LEOBILOC_02420 4.28e-253 - - - S - - - Protein of unknown function (DUF1648)
LEOBILOC_02421 2.51e-72 yodB - - K - - - transcriptional
LEOBILOC_02423 8.46e-301 - - - S - - - SNARE associated Golgi protein
LEOBILOC_02424 1.16e-135 yngC - - S - - - membrane-associated protein
LEOBILOC_02425 1.23e-208 msrR - - K - - - COG1316 Transcriptional regulator
LEOBILOC_02427 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
LEOBILOC_02428 0.0 metH 2.1.1.13 - E ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
LEOBILOC_02429 1.79e-22 csbD - - S - - - Belongs to the UPF0337 (CsbD) family
LEOBILOC_02430 5.89e-113 - - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 ComK protein
LEOBILOC_02431 4.67e-125 - 2.7.7.6 - K ko:K00960 - ko00000,ko01000 Belongs to the sigma-70 factor family. ECF subfamily
LEOBILOC_02432 2.32e-193 - - - E - - - lipolytic protein G-D-S-L family
LEOBILOC_02433 6.45e-158 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
LEOBILOC_02434 1.62e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
LEOBILOC_02435 3.4e-178 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
LEOBILOC_02436 9.74e-200 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LEOBILOC_02437 6.74e-118 cpsE - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
LEOBILOC_02438 1.32e-194 fcl 1.1.1.271 - GM ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
LEOBILOC_02439 1.18e-233 gmd 4.2.1.47 - M ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LEOBILOC_02440 7.36e-25 - - - M - - - PFAM O-Antigen ligase
LEOBILOC_02441 1.24e-64 - - - S - - - PFAM polysaccharide biosynthesis protein
LEOBILOC_02442 4.53e-41 - - - S - - - Glycosyl transferase family 2
LEOBILOC_02443 2.01e-35 - - - H - - - Bacterial transferase hexapeptide (six repeats)
LEOBILOC_02444 5.49e-24 - - - M - - - Glycosyltransferase Family 4
LEOBILOC_02445 2.5e-12 - - - M - - - Glycosyl transferases group 1
LEOBILOC_02446 1.19e-149 rfaG3 - - M - - - Glycosyltransferase Family 4
LEOBILOC_02447 4.32e-109 wecG 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Belongs to the glycosyltransferase 26 family
LEOBILOC_02448 3.14e-257 - 2.7.7.13 - G ko:K00971 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 ko00000,ko00001,ko00002,ko01000 mannose-1-phosphate guanylyltransferase
LEOBILOC_02449 0.0 - - - L - - - Transposase
LEOBILOC_02450 7.31e-113 - - - L ko:K07487 - ko00000 PFAM transposase IS4 family protein
LEOBILOC_02451 8.28e-82 - - - - - - - -
LEOBILOC_02452 3.94e-64 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
LEOBILOC_02453 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
LEOBILOC_02454 0.0 - - - M ko:K20276 ko02024,map02024 ko00000,ko00001 Non-essential cell division protein that could be required for efficient cell constriction
LEOBILOC_02455 1.18e-69 - - - S - - - Helix-turn-helix
LEOBILOC_02456 1.01e-35 - - - E - - - IrrE N-terminal-like domain
LEOBILOC_02457 4.25e-51 - - - E - - - IrrE N-terminal-like domain
LEOBILOC_02458 3.12e-61 - - - L - - - COG2963 Transposase and inactivated derivatives
LEOBILOC_02459 7.52e-198 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
LEOBILOC_02460 1.93e-157 - - - S - - - Antitoxin Phd_YefM, type II toxin-antitoxin system
LEOBILOC_02461 4.7e-177 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LEOBILOC_02462 2.46e-169 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
LEOBILOC_02463 2.06e-29 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
LEOBILOC_02464 4.55e-261 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
LEOBILOC_02465 1.05e-93 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
LEOBILOC_02466 5.44e-85 ylxF - - S - - - MgtE intracellular N domain
LEOBILOC_02467 0.0 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control
LEOBILOC_02468 1.94e-137 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Required for flagellar hook formation. May act as a scaffolding protein
LEOBILOC_02469 3.59e-102 flg - - N - - - Putative flagellar
LEOBILOC_02470 5.18e-173 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
LEOBILOC_02471 4.65e-86 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
LEOBILOC_02472 6.39e-234 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LEOBILOC_02473 1.17e-249 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LEOBILOC_02474 2.57e-78 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
LEOBILOC_02475 3.93e-150 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
LEOBILOC_02476 1.16e-139 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
LEOBILOC_02477 3.82e-52 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
LEOBILOC_02478 1.04e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
LEOBILOC_02479 2.15e-241 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LEOBILOC_02480 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LEOBILOC_02481 3.88e-263 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
LEOBILOC_02482 2.83e-202 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
LEOBILOC_02483 2.22e-152 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
LEOBILOC_02484 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
LEOBILOC_02485 8.31e-90 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
LEOBILOC_02486 1.34e-145 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
LEOBILOC_02487 1.59e-110 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
LEOBILOC_02488 3.37e-175 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEOBILOC_02489 2.97e-111 ylxL - - - - - - -
LEOBILOC_02490 1.05e-175 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
LEOBILOC_02491 2.14e-201 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LEOBILOC_02492 2.67e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
LEOBILOC_02493 3.09e-120 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LEOBILOC_02494 3.43e-192 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LEOBILOC_02495 3.27e-187 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
LEOBILOC_02496 2.1e-270 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
LEOBILOC_02497 5.72e-301 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
LEOBILOC_02498 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LEOBILOC_02499 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEOBILOC_02500 2.23e-107 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
LEOBILOC_02501 4.04e-284 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
LEOBILOC_02502 2.27e-59 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
LEOBILOC_02503 2.13e-64 ylxQ - - J - - - ribosomal protein
LEOBILOC_02504 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LEOBILOC_02505 4.54e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
LEOBILOC_02506 6.7e-74 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LEOBILOC_02507 7.07e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LEOBILOC_02508 6.65e-234 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
LEOBILOC_02509 5e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LEOBILOC_02510 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LEOBILOC_02511 1.41e-266 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
LEOBILOC_02512 1.06e-297 mlpA - - S - - - Belongs to the peptidase M16 family
LEOBILOC_02513 2.52e-51 ymxH - - S - - - YlmC YmxH family
LEOBILOC_02514 4.38e-243 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
LEOBILOC_02515 1.25e-140 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
LEOBILOC_02516 4.2e-242 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LEOBILOC_02517 5.78e-287 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LEOBILOC_02518 2.72e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LEOBILOC_02519 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEOBILOC_02520 1.18e-169 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
LEOBILOC_02521 4.69e-47 - - - S - - - YlzJ-like protein
LEOBILOC_02522 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LEOBILOC_02523 1.43e-252 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
LEOBILOC_02524 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LEOBILOC_02525 3.06e-239 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LEOBILOC_02526 3.76e-219 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LEOBILOC_02527 1.03e-301 albE - - S - - - Peptidase M16
LEOBILOC_02528 1.74e-311 ymfH - - S - - - zinc protease
LEOBILOC_02529 3.66e-184 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
LEOBILOC_02530 3.74e-53 ymfJ - - S - - - Protein of unknown function (DUF3243)
LEOBILOC_02531 5.9e-188 ymfK - - S - - - Protein of unknown function (DUF3388)
LEOBILOC_02532 1.9e-211 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
LEOBILOC_02533 2.55e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LEOBILOC_02534 5.38e-290 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
LEOBILOC_02535 1.53e-243 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LEOBILOC_02536 1.41e-304 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
LEOBILOC_02537 1.02e-194 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
LEOBILOC_02538 1.21e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
LEOBILOC_02539 8.92e-219 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
LEOBILOC_02540 2.55e-315 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
LEOBILOC_02541 0.0 - - - E ko:K14052 - ko00000,ko02000 Amino acid permease
LEOBILOC_02542 0.0 - - - KT - - - COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
LEOBILOC_02543 0.0 - 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LEOBILOC_02544 0.0 - 2.6.1.82 - E ko:K09251 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LEOBILOC_02545 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LEOBILOC_02546 1.8e-84 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
LEOBILOC_02547 4.31e-128 - - - S ko:K06328 - ko00000 Outer spore coat protein E (CotE)
LEOBILOC_02548 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LEOBILOC_02549 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LEOBILOC_02550 2.41e-50 yhjA - - S - - - Excalibur calcium-binding domain
LEOBILOC_02551 1.19e-48 - - - S - - - protein secretion by the type IV secretion system
LEOBILOC_02553 9e-08 - - - - - - - -
LEOBILOC_02554 3.36e-248 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LEOBILOC_02555 1.4e-48 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
LEOBILOC_02557 4.44e-224 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
LEOBILOC_02558 5.18e-291 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LEOBILOC_02559 2.04e-312 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
LEOBILOC_02560 1.48e-215 ypcP - - L - - - 5'3' exonuclease
LEOBILOC_02562 1.59e-37 ypeQ - - S - - - Zinc-finger
LEOBILOC_02563 4.69e-43 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
LEOBILOC_02564 3.17e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
LEOBILOC_02565 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
LEOBILOC_02566 1.86e-109 - - - - - - - -
LEOBILOC_02567 3.18e-155 ypgQ - - S ko:K06950 - ko00000 phosphohydrolase
LEOBILOC_02568 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LEOBILOC_02569 5.47e-219 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
LEOBILOC_02570 2.03e-96 yphP - - S - - - Belongs to the UPF0403 family
LEOBILOC_02571 9.63e-136 ypjP - - S - - - YpjP-like protein
LEOBILOC_02572 3.07e-200 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LEOBILOC_02573 4.8e-119 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LEOBILOC_02574 7.44e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
LEOBILOC_02575 1.37e-178 - - - E - - - COG2755 Lysophospholipase L1 and related esterases
LEOBILOC_02576 7.96e-127 ypmS - - S - - - protein conserved in bacteria
LEOBILOC_02577 0.0 rsmF - - J - - - RNA-binding PUA-like domain of methyltransferase RsmF
LEOBILOC_02578 3.7e-133 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LEOBILOC_02579 5.45e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
LEOBILOC_02580 1.66e-25 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LEOBILOC_02581 6.24e-308 - - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 CHASE3 domain
LEOBILOC_02582 2.13e-48 yozE - - S - - - Belongs to the UPF0346 family
LEOBILOC_02583 1.83e-148 yodN - - - - - - -
LEOBILOC_02584 1.12e-33 yozD - - S - - - YozD-like protein
LEOBILOC_02586 1.34e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
LEOBILOC_02587 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
LEOBILOC_02588 3.1e-91 ypoP - - K - - - transcriptional
LEOBILOC_02589 2.2e-149 ykwD - - J - - - protein with SCP PR1 domains
LEOBILOC_02590 1.83e-316 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
LEOBILOC_02592 5.31e-241 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LEOBILOC_02593 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
LEOBILOC_02594 4.39e-181 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LEOBILOC_02595 8.54e-137 pap2c 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
LEOBILOC_02597 0.0 yfnI 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
LEOBILOC_02598 1.54e-135 laaE - - K - - - Transcriptional regulator
LEOBILOC_02599 1.69e-77 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 lactoylglutathione lyase activity
LEOBILOC_02600 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
LEOBILOC_02601 1.23e-291 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LEOBILOC_02602 5.43e-157 csrR - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEOBILOC_02603 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LEOBILOC_02604 9.57e-106 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
LEOBILOC_02605 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
LEOBILOC_02606 3.84e-280 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
LEOBILOC_02607 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LEOBILOC_02608 8.87e-120 rok - - S - - - Repressor of ComK
LEOBILOC_02609 5.55e-154 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEOBILOC_02611 6.68e-206 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LEOBILOC_02612 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LEOBILOC_02613 1.93e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
LEOBILOC_02614 4.17e-164 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
LEOBILOC_02615 3.75e-135 thiT - - S ko:K16789 - ko00000,ko02000 Proton-coupled thiamine transporter YuaJ
LEOBILOC_02616 3.77e-215 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LEOBILOC_02617 8.76e-104 - - - S - - - Domain in cystathionine beta-synthase and other proteins.
LEOBILOC_02618 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
LEOBILOC_02619 4.89e-144 yocH - - M - - - COG1388 FOG LysM repeat
LEOBILOC_02620 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LEOBILOC_02621 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LEOBILOC_02622 1.99e-146 ycgF - - E - - - Lysine exporter protein LysE YggA
LEOBILOC_02623 2.92e-230 yqxL - - P - - - Mg2 transporter protein
LEOBILOC_02624 1.82e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
LEOBILOC_02625 1.77e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LEOBILOC_02626 8.08e-140 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
LEOBILOC_02627 3.56e-57 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LEOBILOC_02628 1.46e-199 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LEOBILOC_02629 1.16e-61 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LEOBILOC_02630 1.59e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LEOBILOC_02631 7.14e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LEOBILOC_02632 2.03e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LEOBILOC_02633 2.44e-36 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
LEOBILOC_02634 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LEOBILOC_02635 1.48e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LEOBILOC_02636 2.15e-75 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LEOBILOC_02637 9.01e-121 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LEOBILOC_02638 2.03e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LEOBILOC_02639 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LEOBILOC_02640 1.76e-122 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LEOBILOC_02641 1.22e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LEOBILOC_02642 5.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LEOBILOC_02643 2.65e-32 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
LEOBILOC_02644 3.48e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
LEOBILOC_02645 1.14e-292 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LEOBILOC_02646 3.31e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LEOBILOC_02647 1.69e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LEOBILOC_02648 6.28e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LEOBILOC_02649 9.37e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LEOBILOC_02650 9.96e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEOBILOC_02651 8.7e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
LEOBILOC_02653 8.45e-202 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEOBILOC_02654 4.72e-207 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEOBILOC_02655 2.18e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEOBILOC_02656 7.42e-173 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LEOBILOC_02657 2.28e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LEOBILOC_02658 1.05e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
LEOBILOC_02659 1.36e-28 - 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LEOBILOC_02660 0.0 - 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LEOBILOC_02661 0.0 - - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
LEOBILOC_02663 9.55e-289 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
LEOBILOC_02664 6.21e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
LEOBILOC_02665 0.0 lysP - - E ko:K11733 - ko00000,ko02000 amino acid
LEOBILOC_02666 1.73e-107 ybaK - - S - - - Protein of unknown function (DUF2521)
LEOBILOC_02667 2.59e-169 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LEOBILOC_02668 5.43e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
LEOBILOC_02669 4.54e-112 gerD - - S ko:K06294 - ko00000 Spore gernimation protein
LEOBILOC_02670 5.02e-141 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
LEOBILOC_02671 1.48e-274 - - - S - - - Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
LEOBILOC_02672 4.31e-177 pdaB - - G - - - xylanase chitin deacetylase
LEOBILOC_02673 4.77e-42 - - - - - - - -
LEOBILOC_02674 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
LEOBILOC_02675 4.47e-231 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
LEOBILOC_02676 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
LEOBILOC_02677 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
LEOBILOC_02678 2.29e-180 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LEOBILOC_02679 3.5e-308 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LEOBILOC_02680 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
LEOBILOC_02681 9.52e-164 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LEOBILOC_02682 5.06e-280 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
LEOBILOC_02683 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LEOBILOC_02684 1.2e-238 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LEOBILOC_02685 6.4e-54 XAC3035 - - O ko:K06191 - ko00000 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LEOBILOC_02686 2.04e-309 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
LEOBILOC_02688 1.09e-05 copA 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 ATPase, P-type (transporting), HAD superfamily, subfamily IC
LEOBILOC_02689 1.58e-111 - - - S - - - Protein of unknown function (DUF1641)
LEOBILOC_02690 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
LEOBILOC_02691 1.91e-42 - - - - - - - -
LEOBILOC_02693 1.57e-102 - - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
LEOBILOC_02694 1.6e-172 - - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
LEOBILOC_02696 1.66e-24 - - - S - - - transposase or invertase
LEOBILOC_02697 1.82e-21 - - - S - - - transposase or invertase
LEOBILOC_02698 1.64e-25 - - - S - - - transposase or invertase
LEOBILOC_02699 3.18e-208 - - - S - - - transposase or invertase
LEOBILOC_02700 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LEOBILOC_02701 2.54e-112 nhaX - - T - - - Universal stress protein
LEOBILOC_02703 5.34e-244 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LEOBILOC_02704 1.01e-228 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LEOBILOC_02705 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LEOBILOC_02706 4.38e-242 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LEOBILOC_02707 7.38e-225 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEOBILOC_02708 4.48e-206 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEOBILOC_02709 2.4e-168 - - - S ko:K07010 - ko00000,ko01002 Peptidase C26
LEOBILOC_02710 1.77e-236 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
LEOBILOC_02711 2.04e-60 yhdB - - S - - - YhdB-like protein
LEOBILOC_02713 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
LEOBILOC_02714 4.35e-238 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
LEOBILOC_02715 2.07e-173 - - - E - - - GDSL-like Lipase/Acylhydrolase
LEOBILOC_02716 2.13e-101 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
LEOBILOC_02717 3.01e-112 bdbA - - CO - - - Thioredoxin
LEOBILOC_02718 2.35e-117 yhcU - - S - - - Family of unknown function (DUF5365)
LEOBILOC_02719 5.31e-149 ykaA - - P ko:K07220 - ko00000 Protein of unknown function DUF47
LEOBILOC_02720 4.46e-229 pit - - P ko:K03306 - ko00000 phosphate transporter
LEOBILOC_02721 1.74e-135 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LEOBILOC_02723 3.3e-282 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
LEOBILOC_02724 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
LEOBILOC_02725 6.6e-115 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LEOBILOC_02726 7.08e-220 yhbB - - S - - - Putative amidase domain
LEOBILOC_02727 1.29e-282 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LEOBILOC_02728 1.01e-133 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
LEOBILOC_02729 2.95e-211 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
LEOBILOC_02730 1.29e-110 yhjR - - S - - - Rubrerythrin
LEOBILOC_02731 6.5e-212 - 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
LEOBILOC_02732 2.8e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
LEOBILOC_02733 8.56e-151 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LEOBILOC_02734 4.12e-170 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LEOBILOC_02735 3.6e-94 - - - P ko:K02532 - ko00000,ko02000 PFAM major facilitator superfamily MFS_1
LEOBILOC_02736 1.01e-191 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
LEOBILOC_02737 6.83e-274 - 1.1.1.1 - C ko:K13954 ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
LEOBILOC_02738 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 formate acetyltransferase
LEOBILOC_02739 1.15e-185 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LEOBILOC_02740 3.52e-130 - 1.5.1.38 - S ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 ko00000,ko00001,ko01000 FMN reductase
LEOBILOC_02741 1.44e-116 - - - - - - - -
LEOBILOC_02742 4.36e-217 bcrB - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
LEOBILOC_02743 6.74e-214 bcrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LEOBILOC_02744 3.14e-185 - - - E - - - G-D-S-L family
LEOBILOC_02745 3.08e-43 - - - - - - - -
LEOBILOC_02747 2.63e-223 - - - S - - - High confidence in function and specificity
LEOBILOC_02748 8.05e-166 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEOBILOC_02749 0.0 ykoH - - T - - - Histidine kinase
LEOBILOC_02750 3.04e-141 - - - - - - - -
LEOBILOC_02751 9.23e-84 - - - T - - - ECF transporter, substrate-specific component
LEOBILOC_02752 1.74e-65 - - - K ko:K03710 - ko00000,ko03000 UTRA domain
LEOBILOC_02753 2.7e-91 - - - S - - - CHY zinc finger
LEOBILOC_02754 1.42e-269 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LEOBILOC_02755 5.27e-140 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LEOBILOC_02756 2.26e-286 hisD 1.1.1.23, 1.1.1.308 - E ko:K00013,ko:K15509 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LEOBILOC_02757 4.74e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
LEOBILOC_02758 9.55e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LEOBILOC_02759 9.01e-164 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LEOBILOC_02760 7.72e-179 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LEOBILOC_02761 4e-156 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
LEOBILOC_02762 2.08e-54 - - - O - - - Belongs to the sulfur carrier protein TusA family
LEOBILOC_02763 5.13e-309 - - - S ko:K07112 - ko00000 Sulphur transport
LEOBILOC_02764 1.74e-223 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
LEOBILOC_02765 7.49e-283 ktrB - - P ko:K03498 - ko00000,ko02000 COG0168 Trk-type K transport systems, membrane components
LEOBILOC_02766 3.99e-158 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
LEOBILOC_02767 1.62e-174 ykrK - - S - - - Domain of unknown function (DUF1836)
LEOBILOC_02768 1.48e-47 - - - - - - - -
LEOBILOC_02769 6.02e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
LEOBILOC_02770 2.91e-276 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
LEOBILOC_02771 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
LEOBILOC_02772 3.44e-41 - - - S - - - ATP synthase, subunit b
LEOBILOC_02773 2.51e-130 msrA 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LEOBILOC_02775 1.15e-43 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock
LEOBILOC_02776 3.85e-151 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
LEOBILOC_02777 1.07e-210 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
LEOBILOC_02778 2.47e-58 - - - S - - - Protein of unknown function (DUF1292)
LEOBILOC_02779 1.41e-63 yxiS - - - - - - -
LEOBILOC_02780 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
LEOBILOC_02781 1.19e-177 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
LEOBILOC_02782 1.14e-232 bceS 2.7.13.3 - T ko:K11629 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
LEOBILOC_02783 6.9e-166 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEOBILOC_02784 3.63e-143 - - - S - - - Protein of unknown function (DUF1672)
LEOBILOC_02785 1.76e-138 - - - S - - - Protein of unknown function (DUF1672)
LEOBILOC_02786 1.9e-08 - - - - - - - -
LEOBILOC_02787 2.93e-93 - - - K - - - Helix-turn-helix domain
LEOBILOC_02788 1e-254 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
LEOBILOC_02790 1.6e-248 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
LEOBILOC_02791 3.71e-24 - - - - - - - -
LEOBILOC_02792 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LEOBILOC_02793 1.24e-258 yetN - - S - - - Protein of unknown function (DUF3900)
LEOBILOC_02794 4.68e-194 - - - - - - - -
LEOBILOC_02796 1.48e-305 ywoD - - EGP - - - Major facilitator superfamily
LEOBILOC_02797 4.07e-72 - - - S ko:K13628,ko:K15724 - ko00000,ko03016 Heme biosynthesis protein HemY
LEOBILOC_02798 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LEOBILOC_02799 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LEOBILOC_02800 2.36e-56 - - - S - - - Small, acid-soluble spore proteins, alpha/beta type
LEOBILOC_02801 2.11e-80 - - - S ko:K06518 - ko00000,ko02000 Effector of murein hydrolase LrgA
LEOBILOC_02802 3.91e-145 - - - M - - - effector of murein hydrolase
LEOBILOC_02803 0.0 alkK - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LEOBILOC_02804 2.45e-148 - - - M ko:K21471,ko:K21472 - ko00000,ko01000,ko01002,ko01011 lytic transglycosylase activity
LEOBILOC_02805 4.84e-32 ydaS - - S - - - membrane
LEOBILOC_02806 1.14e-26 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
LEOBILOC_02807 5.79e-52 - - - - - - - -
LEOBILOC_02808 5.12e-306 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
LEOBILOC_02809 3.51e-26 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
LEOBILOC_02810 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LEOBILOC_02811 1.76e-06 - - - S - - - Fur-regulated basic protein B
LEOBILOC_02812 4.72e-28 sspN - - S ko:K06431 - ko00000 Small acid-soluble spore protein N family
LEOBILOC_02813 1.26e-42 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
LEOBILOC_02814 1.91e-98 yneP - - S ko:K07107 - ko00000,ko01000 thioesterase
LEOBILOC_02815 3.42e-69 yneQ - - - - - - -
LEOBILOC_02816 1.65e-70 yneR - - S - - - Belongs to the HesB IscA family
LEOBILOC_02817 2.15e-131 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LEOBILOC_02818 3.06e-94 yneT - - S ko:K06929 - ko00000 CoA-binding protein
LEOBILOC_02819 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEOBILOC_02820 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEOBILOC_02821 2.72e-191 - - - - - - - -
LEOBILOC_02822 1.81e-63 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 GDP-mannose mannosyl hydrolase activity
LEOBILOC_02824 1.39e-288 ywdJ - - F - - - Xanthine uracil
LEOBILOC_02825 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LEOBILOC_02826 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LEOBILOC_02828 1.6e-127 - - - O - - - HI0933-like protein
LEOBILOC_02831 3.48e-103 - - - K - - - Acetyltransferase (GNAT) domain
LEOBILOC_02832 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LEOBILOC_02833 2.54e-171 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
LEOBILOC_02834 2.96e-212 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
LEOBILOC_02835 1.84e-23 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
LEOBILOC_02836 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
LEOBILOC_02837 2.12e-274 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
LEOBILOC_02838 0.0 - 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 AMP-dependent synthetase
LEOBILOC_02839 0.0 - 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LEOBILOC_02840 7.31e-316 pspF - - KT - - - Transcriptional regulator
LEOBILOC_02841 1.38e-293 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
LEOBILOC_02842 6.85e-310 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
LEOBILOC_02843 1.94e-95 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
LEOBILOC_02844 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
LEOBILOC_02846 1.46e-272 - - - L - - - Integrase core domain
LEOBILOC_02847 1.82e-176 - - - L - - - PhoH-like protein
LEOBILOC_02848 4.64e-91 - - - L - - - Transposase DDE domain
LEOBILOC_02849 4.96e-70 - - - L - - - Transposase DDE domain
LEOBILOC_02850 2.33e-134 - - - L - - - PFAM Transposase, Mutator
LEOBILOC_02851 4.34e-80 - - - S - - - Protein of unknown function (DUF4064)
LEOBILOC_02852 6.93e-133 - - - K - - - Bacterial regulatory proteins, tetR family
LEOBILOC_02853 4.76e-45 - - - F - - - Belongs to the Nudix hydrolase family
LEOBILOC_02854 2.71e-109 betI1 - - K - - - Transcriptional regulator
LEOBILOC_02855 3.39e-269 - - - EGP - - - Sugar (and other) transporter
LEOBILOC_02856 9.06e-107 - - - Q - - - dioxygenase activity
LEOBILOC_02857 4.69e-63 - - - K - - - helix_turn_helix, arabinose operon control protein
LEOBILOC_02859 9.38e-187 - - - U - - - Type II secretory pathway, component ExeA
LEOBILOC_02860 0.0 - - - L - - - PFAM Mu transposase, C-terminal
LEOBILOC_02861 2.51e-35 - - - E - - - Dihydrouridine synthase (Dus)
LEOBILOC_02862 9.74e-60 - - - L ko:K07483 - ko00000 Transposase
LEOBILOC_02863 3.38e-136 - - - L - - - PFAM Integrase catalytic region
LEOBILOC_02864 2.81e-71 - - - L - - - PFAM Transposase, IS4-like
LEOBILOC_02865 2.69e-22 - - - S - - - Ribbon-helix-helix protein, copG family
LEOBILOC_02866 1.21e-70 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
LEOBILOC_02867 5.83e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
LEOBILOC_02868 6.79e-295 - - GT2,GT4 M ko:K20444 - ko00000,ko01000,ko01005,ko02000 transferase activity, transferring glycosyl groups
LEOBILOC_02869 6.23e-73 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LEOBILOC_02870 1.2e-77 - - - S - - - Protein of unknown function (DUF1430)
LEOBILOC_02871 5.64e-25 - - - - - - - -
LEOBILOC_02872 6.23e-193 - - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LEOBILOC_02873 5.36e-133 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
LEOBILOC_02874 6.82e-208 - - - S - - - Protein of unknown function (DUF1646)
LEOBILOC_02875 1.89e-277 - - - EGP - - - Major Facilitator Superfamily
LEOBILOC_02876 0.0 - 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
LEOBILOC_02877 9.81e-41 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
LEOBILOC_02878 2.96e-72 csoR_2 - - S ko:K21600 - ko00000,ko03000 protein conserved in bacteria
LEOBILOC_02879 1.3e-90 - - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
LEOBILOC_02880 1.46e-97 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LEOBILOC_02881 3.6e-285 - - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LEOBILOC_02882 3.42e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
LEOBILOC_02883 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEOBILOC_02885 8.31e-30 yhjQ - - C - - - COG1145 Ferredoxin
LEOBILOC_02888 4.44e-223 nodB1 - - G - - - deacetylase
LEOBILOC_02891 1.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LEOBILOC_02893 4.15e-313 - - - P - - - Voltage gated chloride channel
LEOBILOC_02894 5.53e-65 - - - P - - - Rhodanese domain protein
LEOBILOC_02895 6.22e-52 csoR - - S - - - protein conserved in bacteria
LEOBILOC_02896 2.22e-187 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
LEOBILOC_02897 7.75e-94 - 2.7.1.199 - G ko:K02777,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
LEOBILOC_02898 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
LEOBILOC_02899 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
LEOBILOC_02900 3.18e-244 araH - - G ko:K10544,ko:K10547 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LEOBILOC_02901 0.0 araG 3.6.3.17 - G ko:K10548 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
LEOBILOC_02902 1.81e-252 chvE - - G ko:K10546 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LEOBILOC_02903 2.11e-271 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
LEOBILOC_02904 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
LEOBILOC_02905 6.9e-167 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
LEOBILOC_02906 0.0 araP - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LEOBILOC_02907 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
LEOBILOC_02908 6.42e-275 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
LEOBILOC_02909 0.0 - - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LEOBILOC_02910 9.81e-165 - - - I - - - Acyl-transferase
LEOBILOC_02911 2.24e-261 - - - M - - - Glycosyl transferase family 2
LEOBILOC_02912 1.3e-169 fabG9 - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LEOBILOC_02913 1.75e-100 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
LEOBILOC_02914 1.9e-278 solA 1.5.3.1 - E ko:K00301,ko:K02846 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
LEOBILOC_02915 1.31e-288 - 1.5.3.1 - E ko:K00303 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
LEOBILOC_02916 0.0 - - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEOBILOC_02917 3.49e-219 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 ornithine cyclodeaminase
LEOBILOC_02920 4.5e-234 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
LEOBILOC_02921 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
LEOBILOC_02922 1.11e-45 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
LEOBILOC_02923 5.46e-113 - - - K - - - Bacterial transcription activator, effector binding domain
LEOBILOC_02924 9.05e-85 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
LEOBILOC_02925 4.29e-40 - - - K - - - Helix-turn-helix XRE-family like proteins
LEOBILOC_02926 1.32e-247 yqjM1 - - C - - - Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
LEOBILOC_02927 3.76e-211 - - - S - - - reductase
LEOBILOC_02928 2.16e-203 dkgB - - S - - - Aldo/keto reductase family
LEOBILOC_02929 5.74e-304 - - - S - - - protein conserved in bacteria
LEOBILOC_02930 7.1e-06 - - - - - - - -
LEOBILOC_02931 1.66e-144 ppiA 5.2.1.8 - O ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LEOBILOC_02932 3.04e-87 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
LEOBILOC_02933 3e-23 - - - S - - - double-stranded DNA endodeoxyribonuclease activity
LEOBILOC_02934 3.79e-22 - - - S - - - transposase or invertase
LEOBILOC_02935 6.13e-279 - - - EGP - - - Transmembrane secretion effector
LEOBILOC_02938 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
LEOBILOC_02939 8.63e-47 ykuS - - S - - - Belongs to the UPF0180 family
LEOBILOC_02940 5.27e-32 - - - - - - - -
LEOBILOC_02941 0.0 - 6.2.1.16 - I ko:K01907 ko00280,ko00650,map00280,map00650 ko00000,ko00001,ko01000,ko01004 AMP-dependent synthetase
LEOBILOC_02942 4.47e-121 - - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
LEOBILOC_02943 3.72e-132 - - - P ko:K07240 - ko00000,ko02000 Chromate transporter
LEOBILOC_02944 2.39e-108 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
LEOBILOC_02945 5.25e-296 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
LEOBILOC_02946 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
LEOBILOC_02947 3.1e-290 - 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
LEOBILOC_02949 7.35e-156 - - - EGP - - - Major facilitator Superfamily
LEOBILOC_02951 2.08e-207 - - - K - - - Sensory domain found in PocR
LEOBILOC_02952 2.57e-291 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEOBILOC_02953 1.48e-272 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
LEOBILOC_02954 7.64e-06 esxA - - S - - - Belongs to the WXG100 family
LEOBILOC_02955 8.59e-60 esxA - - S - - - Belongs to the WXG100 family
LEOBILOC_02957 0.0 yueB - - S - - - domain protein
LEOBILOC_02959 6.32e-55 esaB - - S - - - WXG100 protein secretion system (Wss), protein YukD
LEOBILOC_02960 2.03e-280 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
LEOBILOC_02961 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LEOBILOC_02962 1.69e-34 - - - - - - - -
LEOBILOC_02963 2.38e-37 - - - S - - - Proteins of 100 residues with WXG
LEOBILOC_02964 6.25e-104 - - - S - - - Domain of unknown function (DUF5081)
LEOBILOC_02965 2.71e-39 - - - - - - - -
LEOBILOC_02966 2.78e-152 - - - S - - - domain, Protein
LEOBILOC_02967 6.42e-85 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2247)
LEOBILOC_02968 1.49e-46 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LEOBILOC_02969 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LEOBILOC_02971 2.66e-58 - - - - - - - -
LEOBILOC_02972 1.81e-32 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LEOBILOC_02973 1.66e-304 - - - L - - - Transposase DDE domain group 1
LEOBILOC_02974 8.82e-241 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LEOBILOC_02975 1.11e-92 - 3.1.12.1 - L ko:K07464 - ko00000,ko01000,ko02048 Domain of unknown function DUF83
LEOBILOC_02976 0.0 cas3 - - L ko:K07012 - ko00000,ko01000,ko02048 CRISPR-associated helicase, Cas3
LEOBILOC_02977 2.61e-184 cas5h - - S ko:K19116 - ko00000,ko02048 CRISPR-associated protein Cas5
LEOBILOC_02978 1.62e-227 - - - L ko:K19115 - ko00000,ko02048 CRISPR-associated protein Cas7
LEOBILOC_02979 0.0 csh - - - ko:K19114 - ko00000,ko02048 -
LEOBILOC_02980 4.13e-165 - - - L ko:K19091 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA)
LEOBILOC_02981 0.0 snf - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
LEOBILOC_02982 1.87e-139 - - - C - - - Nitroreductase family
LEOBILOC_02983 1.08e-116 - 1.8.5.2 - S ko:K16937 ko00920,ko01120,map00920,map01120 ko00000,ko00001,ko01000 DoxX
LEOBILOC_02984 5.75e-242 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LEOBILOC_02985 1.55e-149 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LEOBILOC_02986 2.33e-47 yoeD - - G - - - Helix-turn-helix domain
LEOBILOC_02987 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
LEOBILOC_02988 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
LEOBILOC_02989 1.81e-172 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
LEOBILOC_02990 2.13e-256 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
LEOBILOC_02991 9.8e-124 - - - D - - - Hemerythrin HHE cation binding
LEOBILOC_02992 1.11e-195 yxeH - - S - - - hydrolases of the HAD superfamily
LEOBILOC_02993 1.16e-76 - - - S - - - Nitrous oxide-stimulated promoter
LEOBILOC_02994 8.3e-110 - - - G ko:K02755,ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
LEOBILOC_02995 0.0 yfiG - - U ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LEOBILOC_02996 7.79e-262 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LEOBILOC_02998 2.03e-96 ywnF - - S - - - Family of unknown function (DUF5392)
LEOBILOC_02999 2.79e-176 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
LEOBILOC_03000 0.0 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LEOBILOC_03001 4.35e-77 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
LEOBILOC_03002 6.69e-129 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
LEOBILOC_03003 7.54e-230 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dihydroxyacetone kinase DhaK, subunit
LEOBILOC_03004 2.63e-223 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
LEOBILOC_03006 3.15e-175 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
LEOBILOC_03007 6.38e-297 - - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LEOBILOC_03009 9.51e-193 - - - S ko:K07090 - ko00000 membrane transporter protein
LEOBILOC_03022 3.79e-121 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
LEOBILOC_03023 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
LEOBILOC_03024 1.53e-139 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
LEOBILOC_03025 6.8e-176 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEOBILOC_03026 2.7e-104 rsbW 2.7.11.1 - T ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
LEOBILOC_03027 2.52e-75 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
LEOBILOC_03028 5.01e-247 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
LEOBILOC_03029 5.15e-91 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
LEOBILOC_03030 1.39e-72 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
LEOBILOC_03031 1.02e-194 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
LEOBILOC_03032 1.25e-74 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
LEOBILOC_03033 1.47e-55 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
LEOBILOC_03034 8.36e-278 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LEOBILOC_03035 4.94e-245 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
LEOBILOC_03036 5.48e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LEOBILOC_03037 3.46e-137 ydcA 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
LEOBILOC_03038 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LEOBILOC_03039 3.66e-82 - - - - - - - -
LEOBILOC_03040 3.56e-138 ycgF - - E - - - Lysine exporter protein LysE YggA
LEOBILOC_03041 6.6e-158 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LEOBILOC_03042 6.84e-226 yvdE - - K - - - Transcriptional regulator
LEOBILOC_03043 0.0 - 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
LEOBILOC_03044 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
LEOBILOC_03045 4.79e-311 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
LEOBILOC_03046 7.1e-310 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
LEOBILOC_03047 9.8e-197 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
LEOBILOC_03048 6.02e-185 malA - - S - - - Protein of unknown function (DUF1189)
LEOBILOC_03049 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
LEOBILOC_03050 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
LEOBILOC_03051 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LEOBILOC_03052 4.84e-256 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
LEOBILOC_03053 5.71e-192 - - - - - - - -
LEOBILOC_03054 5.74e-301 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LEOBILOC_03055 1.34e-108 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
LEOBILOC_03056 3.61e-316 - - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LEOBILOC_03058 0.0 - - - S - - - Zinc finger, swim domain protein
LEOBILOC_03059 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
LEOBILOC_03061 3.69e-92 ywpF - - S - - - YwpF-like protein
LEOBILOC_03062 5.41e-84 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
LEOBILOC_03064 4.3e-96 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LEOBILOC_03065 1.5e-192 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
LEOBILOC_03066 9.06e-187 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
LEOBILOC_03067 4.13e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
LEOBILOC_03069 3.27e-57 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
LEOBILOC_03070 7.35e-174 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
LEOBILOC_03071 4.86e-235 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
LEOBILOC_03072 8.89e-305 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEOBILOC_03073 1.97e-173 ywmB - - S - - - TATA-box binding
LEOBILOC_03074 1.1e-46 ywzB - - S - - - membrane
LEOBILOC_03075 1.03e-87 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
LEOBILOC_03076 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LEOBILOC_03077 9.39e-196 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LEOBILOC_03078 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LEOBILOC_03079 2.12e-114 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEOBILOC_03080 2.3e-72 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LEOBILOC_03081 1.21e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEOBILOC_03082 4.65e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
LEOBILOC_03083 1.92e-75 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase I chain
LEOBILOC_03084 6.42e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LEOBILOC_03085 2.43e-304 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LEOBILOC_03086 2.47e-131 ywlG - - S - - - Belongs to the UPF0340 family
LEOBILOC_03087 4.42e-105 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
LEOBILOC_03089 9.72e-266 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Chemotaxis
LEOBILOC_03090 4.56e-104 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LEOBILOC_03091 6.78e-118 mntP - - P - - - Probably functions as a manganese efflux pump
LEOBILOC_03092 2.57e-250 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LEOBILOC_03093 2.38e-173 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
LEOBILOC_03094 4.04e-207 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LEOBILOC_03095 2.55e-247 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LEOBILOC_03096 8.72e-65 - - - S - - - Domain of unknown function (DUF1851)
LEOBILOC_03097 2.94e-121 - - - T - - - His Kinase A (phosphoacceptor) domain
LEOBILOC_03098 1.15e-313 - - - G - - - MFS/sugar transport protein
LEOBILOC_03099 0.0 - 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
LEOBILOC_03100 1.14e-178 - - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEOBILOC_03101 9.33e-275 - - - GK - - - ROK family
LEOBILOC_03102 3.43e-284 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LEOBILOC_03103 7.88e-94 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LEOBILOC_03106 0.0 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LEOBILOC_03107 4.81e-278 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
LEOBILOC_03108 8.1e-281 yhjX - - P ko:K08177 - ko00000,ko02000 Major facilitator superfamily
LEOBILOC_03109 2.21e-176 - - - T ko:K02477 - ko00000,ko02022 LytTr DNA-binding domain
LEOBILOC_03110 0.0 ypdA3 2.7.13.3 - T ko:K02478,ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
LEOBILOC_03111 6.54e-250 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
LEOBILOC_03112 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
LEOBILOC_03113 4.07e-138 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
LEOBILOC_03114 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
LEOBILOC_03115 1.62e-313 - - - S - - - Protein of unknown function N-terminus (DUF3323)
LEOBILOC_03116 0.0 - - - D - - - Putative exonuclease SbcCD, C subunit
LEOBILOC_03117 2.27e-293 - - - S - - - Protein of unknown function (DUF2398)
LEOBILOC_03119 0.0 - - - S - - - Protein of unknown function (DUF2397)
LEOBILOC_03120 1.94e-105 - - - - - - - -
LEOBILOC_03122 1.56e-257 - - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LEOBILOC_03123 1.51e-200 yoaT - - S - - - Protein of unknown function (DUF817)
LEOBILOC_03124 8.52e-41 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
LEOBILOC_03125 9.63e-100 yoaS - - S - - - Protein of unknown function (DUF2975)
LEOBILOC_03126 4.88e-79 - - - - ko:K06327 - ko00000 -
LEOBILOC_03127 7.26e-303 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEOBILOC_03128 1.94e-99 - - - S ko:K09793 - ko00000 protein conserved in bacteria
LEOBILOC_03129 0.0 - - - S ko:K08981 - ko00000 Bacterial PH domain
LEOBILOC_03130 2.44e-111 - - - S ko:K09167 - ko00000 Bacterial PH domain
LEOBILOC_03131 1.79e-112 - - - S - - - AAA domain
LEOBILOC_03132 7.15e-43 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
LEOBILOC_03133 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
LEOBILOC_03134 1.41e-243 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LEOBILOC_03135 4.5e-66 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LEOBILOC_03136 1.62e-187 - 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LEOBILOC_03137 4.96e-186 - - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
LEOBILOC_03138 5.06e-235 fabH5 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III
LEOBILOC_03139 8.01e-77 - - - - - - - -
LEOBILOC_03141 0.0 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
LEOBILOC_03142 2.69e-22 - - - S - - - Ribbon-helix-helix protein, copG family
LEOBILOC_03143 4.77e-100 - - - F - - - Belongs to the Nudix hydrolase family
LEOBILOC_03144 6.52e-63 - - - F - - - nucleoside 2-deoxyribosyltransferase
LEOBILOC_03145 1.14e-145 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LEOBILOC_03146 9.98e-87 - - - Q - - - methyltransferase
LEOBILOC_03147 1.99e-158 - 2.5.1.2 - M ko:K10811 ko00730,map00730 ko00000,ko00001,ko01000 transport
LEOBILOC_03148 1.45e-314 thiP - - F - - - Permease for cytosine/purines, uracil, thiamine, allantoin
LEOBILOC_03149 3.69e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LEOBILOC_03150 7.41e-177 fabG5 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
LEOBILOC_03151 6.89e-170 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LEOBILOC_03152 1.01e-186 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LEOBILOC_03153 9.04e-145 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LEOBILOC_03154 6.67e-158 yflK - - S - - - protein conserved in bacteria
LEOBILOC_03155 7.75e-62 - - - - - - - -
LEOBILOC_03156 4.85e-258 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LEOBILOC_03157 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LEOBILOC_03158 3.84e-190 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LEOBILOC_03159 4.15e-145 ccpN - - K - - - CBS domain
LEOBILOC_03160 1.02e-184 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
LEOBILOC_03161 8.43e-13 - - - S - - - YqzL-like protein
LEOBILOC_03162 3.22e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LEOBILOC_03163 6.81e-86 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
LEOBILOC_03164 1.62e-105 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LEOBILOC_03165 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
LEOBILOC_03166 4.09e-222 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
LEOBILOC_03167 2.54e-286 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
LEOBILOC_03168 1.56e-60 yqfC - - S - - - sporulation protein YqfC
LEOBILOC_03169 1.07e-93 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
LEOBILOC_03170 3.56e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
LEOBILOC_03171 3.28e-62 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
LEOBILOC_03172 3.37e-200 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
LEOBILOC_03173 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
LEOBILOC_03174 1.14e-174 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LEOBILOC_03175 7.95e-222 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
LEOBILOC_03176 7.38e-274 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LEOBILOC_03177 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
LEOBILOC_03178 5.59e-126 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LEOBILOC_03179 1.59e-243 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LEOBILOC_03180 5.45e-280 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
LEOBILOC_03181 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LEOBILOC_03182 1.12e-286 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
LEOBILOC_03183 4.85e-257 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LEOBILOC_03184 3.34e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
LEOBILOC_03185 1.41e-241 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
LEOBILOC_03186 1.18e-11 - - - S - - - YqzM-like protein
LEOBILOC_03187 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
LEOBILOC_03188 2.09e-143 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 COG2131 Deoxycytidylate deaminase
LEOBILOC_03189 7.79e-135 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
LEOBILOC_03190 6.61e-190 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LEOBILOC_03191 3.18e-189 - - - S - - - Methyltransferase domain
LEOBILOC_03192 1.02e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LEOBILOC_03193 9.63e-130 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
LEOBILOC_03194 2.28e-137 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LEOBILOC_03195 2.57e-60 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
LEOBILOC_03196 3.2e-205 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LEOBILOC_03197 2.28e-272 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LEOBILOC_03198 1.11e-122 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
LEOBILOC_03199 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
LEOBILOC_03200 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
LEOBILOC_03201 1.72e-247 ysfB - - KT ko:K02647 - ko00000,ko03000 regulator
LEOBILOC_03202 2.69e-288 mco - - Q - - - multicopper oxidases
LEOBILOC_03203 3.93e-94 - - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LEOBILOC_03204 1.19e-41 - - - S ko:K08982 - ko00000 Short C-terminal domain
LEOBILOC_03205 1.17e-119 stoA - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LEOBILOC_03206 8.38e-138 - - - S ko:K06872 - ko00000 TPM domain
LEOBILOC_03207 1.85e-124 lemA - - S ko:K03744 - ko00000 LemA family
LEOBILOC_03208 4.78e-79 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEOBILOC_03209 3.46e-95 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEOBILOC_03210 2.98e-152 - - - S - - - VIT family
LEOBILOC_03211 5.45e-204 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
LEOBILOC_03212 7.73e-22 sda - - S ko:K06371 - ko00000 Sporulation inhibitor A
LEOBILOC_03213 2.05e-126 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LEOBILOC_03214 3.64e-162 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEOBILOC_03216 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
LEOBILOC_03217 3.96e-137 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
LEOBILOC_03219 2.49e-11 - - - S - - - YrhC-like protein
LEOBILOC_03220 7.42e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LEOBILOC_03221 2.82e-40 yrzA - - S - - - Protein of unknown function (DUF2536)
LEOBILOC_03222 2.18e-99 yrrS - - S - - - Protein of unknown function (DUF1510)
LEOBILOC_03223 7.42e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LEOBILOC_03224 8.74e-146 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
LEOBILOC_03225 9.09e-149 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
LEOBILOC_03226 2.62e-261 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LEOBILOC_03227 9.07e-61 yrzB - - S - - - Belongs to the UPF0473 family
LEOBILOC_03228 7.49e-91 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LEOBILOC_03229 2.76e-59 yrzL - - S - - - Belongs to the UPF0297 family
LEOBILOC_03230 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LEOBILOC_03231 8.49e-245 yrrI - - S - - - AI-2E family transporter
LEOBILOC_03233 3.5e-40 yrzR - - - - - - -
LEOBILOC_03234 1.07e-87 yndM - - S - - - Protein of unknown function (DUF2512)
LEOBILOC_03235 3.71e-76 - - - K ko:K03719 - ko00000,ko03000,ko03036 helix_turn_helix ASNC type
LEOBILOC_03236 5.08e-222 pdh 1.4.1.20 - E ko:K00270 ko00350,ko00360,ko00400,ko01100,ko01110,ko01130,map00350,map00360,map00400,map01100,map01110,map01130 ko00000,ko00001,ko01000 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
LEOBILOC_03237 1.2e-212 - 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
LEOBILOC_03238 1.56e-203 pdhB2 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain
LEOBILOC_03239 1.12e-198 pdhC2 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
LEOBILOC_03240 3.08e-245 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LEOBILOC_03241 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LEOBILOC_03242 9.45e-160 yrrB - - S - - - COG0457 FOG TPR repeat
LEOBILOC_03243 1.76e-282 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LEOBILOC_03244 2.24e-266 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LEOBILOC_03245 1.24e-94 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
LEOBILOC_03246 1.35e-236 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
LEOBILOC_03247 8e-178 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LEOBILOC_03248 5.92e-170 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LEOBILOC_03249 1.35e-107 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
LEOBILOC_03250 2.31e-52 - - - - - - - -
LEOBILOC_03251 7.57e-103 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
LEOBILOC_03252 1.27e-54 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
LEOBILOC_03254 3.75e-212 adcA - - P ko:K09815,ko:K09818 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LEOBILOC_03255 5.75e-33 - - - S - - - Domain of Unknown Function (DUF1540)
LEOBILOC_03256 8.1e-261 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
LEOBILOC_03257 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LEOBILOC_03258 3.06e-199 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LEOBILOC_03259 3.41e-189 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
LEOBILOC_03260 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LEOBILOC_03261 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
LEOBILOC_03262 1.25e-211 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
LEOBILOC_03283 3.29e-234 yaaC - - S - - - YaaC-like Protein
LEOBILOC_03284 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LEOBILOC_03285 0.0 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LEOBILOC_03286 9.82e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LEOBILOC_03287 2.28e-133 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LEOBILOC_03288 1.18e-291 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LEOBILOC_03290 1.2e-162 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
LEOBILOC_03291 6.43e-153 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
LEOBILOC_03292 0.0 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
LEOBILOC_03294 1.78e-113 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LEOBILOC_03295 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEOBILOC_03296 1.39e-50 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LEOBILOC_03297 4.93e-141 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LEOBILOC_03298 1.58e-11 yaaL - - S - - - Protein of unknown function (DUF2508)
LEOBILOC_03299 8.4e-51 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
LEOBILOC_03300 2.03e-258 yuxJ - - EGP - - - Major facilitator superfamily
LEOBILOC_03301 7.74e-86 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
LEOBILOC_03302 1.38e-82 yuzC - - - - - - -
LEOBILOC_03304 1.93e-246 gerKB - - E ko:K06296 - ko00000,ko02000 Spore germination protein
LEOBILOC_03305 1.42e-286 gerKC - - S ko:K06297 - ko00000 spore germination
LEOBILOC_03306 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
LEOBILOC_03308 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LEOBILOC_03309 1.07e-138 yuiC - - S - - - protein conserved in bacteria
LEOBILOC_03310 1.04e-61 yuiB - - S - - - Putative membrane protein
LEOBILOC_03311 1.41e-292 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LEOBILOC_03312 3.69e-232 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
LEOBILOC_03313 7.12e-73 - - - S - - - response to antibiotic
LEOBILOC_03314 4.36e-100 - - - S - - - response to antibiotic
LEOBILOC_03315 1.17e-90 ycdA - - S - - - Domain of unknown function (DUF4352)
LEOBILOC_03316 4.8e-83 yutM - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
LEOBILOC_03317 3.46e-80 yuzD - - S - - - protein conserved in bacteria
LEOBILOC_03318 6.83e-50 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
LEOBILOC_03319 4.28e-254 yutH - - S - - - Spore coat protein
LEOBILOC_03320 5.12e-112 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
LEOBILOC_03321 2.39e-178 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LEOBILOC_03322 5.36e-97 yutE - - S - - - Protein of unknown function DUF86
LEOBILOC_03323 4.18e-64 yutD - - S - - - protein conserved in bacteria
LEOBILOC_03324 3.37e-220 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LEOBILOC_03325 8.26e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
LEOBILOC_03326 2.03e-163 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
LEOBILOC_03327 3.71e-64 yunC - - S - - - Domain of unknown function (DUF1805)
LEOBILOC_03328 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LEOBILOC_03329 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
LEOBILOC_03330 2.1e-99 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
LEOBILOC_03331 8.03e-296 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LEOBILOC_03332 5e-310 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
LEOBILOC_03333 2.3e-184 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LEOBILOC_03335 2.79e-69 yusE - - CO - - - Thioredoxin
LEOBILOC_03336 1.7e-84 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
LEOBILOC_03337 3.13e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
LEOBILOC_03338 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
LEOBILOC_03339 5.89e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
LEOBILOC_03340 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
LEOBILOC_03341 3.69e-21 - - - S - - - YuzL-like protein
LEOBILOC_03342 8.24e-56 - - - - - - - -
LEOBILOC_03343 7.36e-48 yusN - - M - - - Coat F domain
LEOBILOC_03344 1.06e-09 yusN - - M - - - Coat F domain
LEOBILOC_03345 7.48e-261 - - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
LEOBILOC_03346 1.4e-73 ydbP - - CO - - - Thioredoxin
LEOBILOC_03347 0.0 cls2 - - I - - - PLD-like domain
LEOBILOC_03348 2.88e-10 - - - - - - - -
LEOBILOC_03349 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LEOBILOC_03351 7.61e-247 M1-600 - - T - - - Putative diguanylate phosphodiesterase
LEOBILOC_03352 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LEOBILOC_03353 4.97e-138 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
LEOBILOC_03354 3.17e-184 - - - G - - - Polysaccharide deacetylase
LEOBILOC_03355 1.96e-312 ugtP5 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Monogalactosyldiacylglycerol (MGDG) synthase
LEOBILOC_03356 4.34e-184 - - - - - - - -
LEOBILOC_03357 9.54e-113 - - - S - - - Putative zinc-finger
LEOBILOC_03358 1.34e-121 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LEOBILOC_03359 1.11e-285 ykoN 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
LEOBILOC_03360 0.0 - - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
LEOBILOC_03361 0.0 - - - NU ko:K02650 ko02020,map02020 ko00000,ko00001,ko02035,ko02044 cell adhesion
LEOBILOC_03362 7.77e-235 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LEOBILOC_03363 6.62e-231 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
LEOBILOC_03364 3.1e-212 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LEOBILOC_03365 2.05e-181 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEOBILOC_03366 0.0 - - - G ko:K03292 - ko00000 MFS/sugar transport protein
LEOBILOC_03367 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
LEOBILOC_03368 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
LEOBILOC_03369 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
LEOBILOC_03370 8.17e-242 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
LEOBILOC_03371 3.67e-154 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
LEOBILOC_03372 9.33e-177 - - - K - - - helix_turn_helix isocitrate lyase regulation

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)