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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NBNEAFNA_00001	9.07e-261	-	-	-	-	-	-	-	-
NBNEAFNA_00002	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NBNEAFNA_00003	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NBNEAFNA_00004	4.22e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NBNEAFNA_00005	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NBNEAFNA_00006	1.39e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
NBNEAFNA_00007	1.8e-249	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
NBNEAFNA_00008	4.82e-84	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
NBNEAFNA_00009	9.35e-132	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
NBNEAFNA_00015	1.83e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
NBNEAFNA_00016	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
NBNEAFNA_00017	1.21e-06	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NBNEAFNA_00018	1.89e-151	-	-	-	I	-	-	-	phosphatase
NBNEAFNA_00019	1.44e-104	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
NBNEAFNA_00020	9.53e-163	-	-	-	S	-	-	-	Putative threonine/serine exporter
NBNEAFNA_00021	6e-41	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
NBNEAFNA_00022	2.22e-159	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
NBNEAFNA_00023	3.18e-209	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
NBNEAFNA_00024	7.03e-150	-	-	-	S	-	-	-	membrane
NBNEAFNA_00025	1.11e-140	-	-	-	S	-	-	-	VIT family
NBNEAFNA_00026	4.64e-106	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
NBNEAFNA_00027	6.59e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NBNEAFNA_00028	1.57e-194	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NBNEAFNA_00029	7.44e-143	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NBNEAFNA_00030	8.58e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NBNEAFNA_00031	3.54e-276	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NBNEAFNA_00032	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NBNEAFNA_00033	1.52e-70	-	-	-	-	-	-	-	-
NBNEAFNA_00034	1.08e-97	-	-	-	K	-	-	-	MerR HTH family regulatory protein
NBNEAFNA_00035	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NBNEAFNA_00036	9.06e-150	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
NBNEAFNA_00037	3.05e-203	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NBNEAFNA_00039	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NBNEAFNA_00040	6.53e-133	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
NBNEAFNA_00041	2.44e-189	-	-	-	I	-	-	-	Alpha beta
NBNEAFNA_00042	8.67e-21	-	-	-	I	-	-	-	Alpha beta
NBNEAFNA_00043	1.09e-251	qacA	-	-	EGP	-	-	-	Major Facilitator
NBNEAFNA_00044	1.83e-150	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
NBNEAFNA_00045	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
NBNEAFNA_00046	1.63e-201	-	-	-	K	-	-	-	LysR family
NBNEAFNA_00047	2.07e-142	-	-	-	I	-	-	-	Alpha/beta hydrolase family
NBNEAFNA_00048	9.53e-195	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NBNEAFNA_00049	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
NBNEAFNA_00050	2.32e-204	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
NBNEAFNA_00051	2.56e-56	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
NBNEAFNA_00052	3.81e-187	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NBNEAFNA_00053	2.43e-225	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
NBNEAFNA_00054	1.24e-157	citR	-	-	K	-	-	-	sugar-binding domain protein
NBNEAFNA_00055	3.04e-216	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
NBNEAFNA_00056	2.1e-166	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NBNEAFNA_00057	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
NBNEAFNA_00058	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NBNEAFNA_00059	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
NBNEAFNA_00060	2.21e-198	mleR	-	-	K	-	-	-	LysR family
NBNEAFNA_00061	1.17e-143	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NBNEAFNA_00062	2.61e-261	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
NBNEAFNA_00063	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
NBNEAFNA_00064	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
NBNEAFNA_00067	6.92e-31	-	-	-	-	-	-	-	-
NBNEAFNA_00068	1.1e-256	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
NBNEAFNA_00069	3.1e-96	-	-	-	-	-	-	-	-
NBNEAFNA_00070	6.09e-277	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NBNEAFNA_00071	7.93e-178	-	-	-	V	-	-	-	Beta-lactamase enzyme family
NBNEAFNA_00072	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
NBNEAFNA_00073	1.09e-275	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
NBNEAFNA_00074	0.0	arcT	-	-	E	-	-	-	Dipeptidase
NBNEAFNA_00075	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
NBNEAFNA_00076	2.83e-229	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
NBNEAFNA_00077	1.31e-35	-	-	-	EGP	-	-	-	Major Facilitator
NBNEAFNA_00078	2.55e-42	-	-	-	EGP	-	-	-	Major Facilitator
NBNEAFNA_00079	3.16e-143	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
NBNEAFNA_00080	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
NBNEAFNA_00081	1.65e-145	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
NBNEAFNA_00082	3.24e-120	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NBNEAFNA_00083	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NBNEAFNA_00084	8.75e-236	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NBNEAFNA_00085	4.99e-65	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
NBNEAFNA_00086	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
NBNEAFNA_00087	1.61e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NBNEAFNA_00088	1.2e-202	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NBNEAFNA_00089	2.41e-236	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
NBNEAFNA_00090	1.08e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NBNEAFNA_00091	3.04e-176	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
NBNEAFNA_00092	1.21e-178	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
NBNEAFNA_00093	1.33e-166	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
NBNEAFNA_00094	1.25e-202	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
NBNEAFNA_00095	4.79e-222	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NBNEAFNA_00096	3.93e-270	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
NBNEAFNA_00097	4.7e-205	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
NBNEAFNA_00098	2.74e-112	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
NBNEAFNA_00099	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NBNEAFNA_00100	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
NBNEAFNA_00101	2.12e-19	-	-	-	-	-	-	-	-
NBNEAFNA_00102	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NBNEAFNA_00103	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NBNEAFNA_00104	3.12e-315	steT	-	-	E	ko:K03294	-	ko00000	amino acid
NBNEAFNA_00105	2.21e-205	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
NBNEAFNA_00106	4.03e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
NBNEAFNA_00107	1.94e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
NBNEAFNA_00109	1.83e-21	-	-	-	-	-	-	-	-
NBNEAFNA_00110	2.37e-307	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
NBNEAFNA_00111	2.73e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NBNEAFNA_00113	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NBNEAFNA_00114	3.1e-289	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
NBNEAFNA_00115	2.51e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NBNEAFNA_00116	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NBNEAFNA_00117	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
NBNEAFNA_00118	5.14e-268	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
NBNEAFNA_00119	2.39e-311	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
NBNEAFNA_00120	3.74e-26	XK27_07210	-	-	S	-	-	-	B3 4 domain
NBNEAFNA_00121	1.14e-117	-	-	-	-	-	-	-	-
NBNEAFNA_00122	4.52e-160	pnb	-	-	C	-	-	-	nitroreductase
NBNEAFNA_00123	5.06e-84	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
NBNEAFNA_00124	1.08e-268	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
NBNEAFNA_00125	2.91e-175	yqeM	-	-	Q	-	-	-	Methyltransferase
NBNEAFNA_00126	3.75e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NBNEAFNA_00127	4.71e-142	yqeK	-	-	H	-	-	-	Hydrolase, HD family
NBNEAFNA_00128	5.5e-155	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NBNEAFNA_00129	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
NBNEAFNA_00130	3.14e-278	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
NBNEAFNA_00131	2.61e-123	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
NBNEAFNA_00132	1.8e-150	-	-	-	EGP	-	-	-	Major Facilitator
NBNEAFNA_00133	1.03e-87	-	-	-	K	-	-	-	Transcriptional regulator
NBNEAFNA_00134	7.55e-53	-	-	-	-	-	-	-	-
NBNEAFNA_00135	0.0	ydaO	-	-	E	-	-	-	amino acid
NBNEAFNA_00136	0.0	-	-	-	E	-	-	-	amino acid
NBNEAFNA_00137	3.57e-55	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
NBNEAFNA_00138	1.72e-212	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NBNEAFNA_00139	3.54e-120	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NBNEAFNA_00140	1.6e-73	-	-	-	S	-	-	-	Conserved hypothetical protein 698
NBNEAFNA_00141	4e-127	-	-	-	S	-	-	-	Conserved hypothetical protein 698
NBNEAFNA_00142	5.89e-171	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NBNEAFNA_00143	4.4e-208	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
NBNEAFNA_00144	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NBNEAFNA_00145	2.12e-162	ybbR	-	-	S	-	-	-	YbbR-like protein
NBNEAFNA_00146	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NBNEAFNA_00147	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NBNEAFNA_00148	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
NBNEAFNA_00149	1.01e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NBNEAFNA_00150	2.16e-212	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NBNEAFNA_00151	2.27e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
NBNEAFNA_00152	6.15e-132	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NBNEAFNA_00153	6.13e-100	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
NBNEAFNA_00154	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NBNEAFNA_00155	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NBNEAFNA_00156	1.51e-203	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
NBNEAFNA_00157	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
NBNEAFNA_00158	1.25e-113	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NBNEAFNA_00159	2.89e-37	-	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
NBNEAFNA_00160	1.24e-189	-	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
NBNEAFNA_00161	8.14e-143	-	-	-	S	-	-	-	Membrane
NBNEAFNA_00162	4.82e-156	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
NBNEAFNA_00163	9.38e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NBNEAFNA_00164	1.84e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NBNEAFNA_00166	4.25e-187	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
NBNEAFNA_00167	2.03e-78	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
NBNEAFNA_00168	8.94e-274	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
NBNEAFNA_00169	4.36e-102	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NBNEAFNA_00170	6.94e-138	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NBNEAFNA_00171	2.79e-224	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NBNEAFNA_00172	2.07e-89	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
NBNEAFNA_00173	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NBNEAFNA_00174	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NBNEAFNA_00175	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NBNEAFNA_00176	1.14e-119	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NBNEAFNA_00177	2.42e-92	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NBNEAFNA_00178	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NBNEAFNA_00179	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
NBNEAFNA_00180	4.63e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
NBNEAFNA_00181	4.71e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
NBNEAFNA_00182	1.69e-241	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
NBNEAFNA_00183	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NBNEAFNA_00184	5.49e-149	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NBNEAFNA_00185	1.74e-291	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NBNEAFNA_00186	4.43e-250	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NBNEAFNA_00187	6.47e-209	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NBNEAFNA_00188	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NBNEAFNA_00189	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
NBNEAFNA_00190	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
NBNEAFNA_00191	4e-172	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
NBNEAFNA_00192	1.14e-296	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
NBNEAFNA_00193	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
NBNEAFNA_00194	5.07e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NBNEAFNA_00195	4.19e-303	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
NBNEAFNA_00196	6.78e-227	ampC	-	-	V	-	-	-	Beta-lactamase
NBNEAFNA_00197	2.02e-59	-	-	-	-	-	-	-	-
NBNEAFNA_00198	0.0	-	-	-	M	-	-	-	domain protein
NBNEAFNA_00199	5.64e-119	-	-	-	-	-	-	-	-
NBNEAFNA_00201	1.55e-45	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
NBNEAFNA_00202	2.49e-73	-	-	-	-	-	-	-	-
NBNEAFNA_00204	1.1e-113	-	-	-	-	-	-	-	-
NBNEAFNA_00205	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
NBNEAFNA_00206	3.66e-64	-	-	-	S	-	-	-	Cupredoxin-like domain
NBNEAFNA_00207	7.61e-81	-	-	-	S	-	-	-	Cupredoxin-like domain
NBNEAFNA_00208	8.21e-133	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
NBNEAFNA_00209	3.71e-205	-	-	-	EG	-	-	-	EamA-like transporter family
NBNEAFNA_00210	9.27e-220	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
NBNEAFNA_00211	9.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NBNEAFNA_00212	3.71e-199	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
NBNEAFNA_00214	1.66e-107	lytE	-	-	M	-	-	-	Lysin motif
NBNEAFNA_00215	2.49e-187	-	-	-	S	-	-	-	Cof-like hydrolase
NBNEAFNA_00216	1.01e-102	-	-	-	K	-	-	-	Transcriptional regulator
NBNEAFNA_00217	0.0	oatA	-	-	I	-	-	-	Acyltransferase
NBNEAFNA_00218	1.01e-67	-	-	-	-	-	-	-	-
NBNEAFNA_00219	1.3e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NBNEAFNA_00220	5.33e-147	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NBNEAFNA_00221	9.28e-121	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
NBNEAFNA_00222	3.21e-168	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NBNEAFNA_00223	2.52e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
NBNEAFNA_00224	5.25e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
NBNEAFNA_00225	3.76e-269	yttB	-	-	EGP	-	-	-	Major Facilitator
NBNEAFNA_00226	1.5e-78	-	-	-	-	-	-	-	-
NBNEAFNA_00227	1.86e-210	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
NBNEAFNA_00228	1.38e-127	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
NBNEAFNA_00230	5.39e-96	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
NBNEAFNA_00231	4.35e-33	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
NBNEAFNA_00232	1.64e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
NBNEAFNA_00233	9.27e-75	-	-	-	S	-	-	-	Small secreted protein
NBNEAFNA_00234	7.19e-150	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
NBNEAFNA_00235	4.48e-231	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
NBNEAFNA_00236	5.18e-134	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NBNEAFNA_00237	1.83e-180	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NBNEAFNA_00238	0.0	-	-	-	EGP	-	-	-	Major Facilitator
NBNEAFNA_00239	3.59e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
NBNEAFNA_00240	1.11e-299	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NBNEAFNA_00241	8.18e-134	-	-	-	V	-	-	-	VanZ like family
NBNEAFNA_00242	7.03e-33	-	-	-	-	-	-	-	-
NBNEAFNA_00243	1.97e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
NBNEAFNA_00244	1.48e-225	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NBNEAFNA_00245	4.62e-252	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NBNEAFNA_00246	7.34e-290	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NBNEAFNA_00247	3.2e-49	-	-	-	-	-	-	-	-
NBNEAFNA_00248	6.85e-13	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
NBNEAFNA_00249	6.53e-101	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
NBNEAFNA_00250	2.3e-52	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
NBNEAFNA_00251	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
NBNEAFNA_00252	3.08e-156	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NBNEAFNA_00253	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NBNEAFNA_00254	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NBNEAFNA_00255	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NBNEAFNA_00256	1.89e-151	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
NBNEAFNA_00257	3.65e-308	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NBNEAFNA_00258	5.1e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NBNEAFNA_00259	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
NBNEAFNA_00260	1.27e-66	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NBNEAFNA_00261	9.48e-130	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NBNEAFNA_00262	2.93e-198	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NBNEAFNA_00263	1.28e-18	-	-	-	-	-	-	-	-
NBNEAFNA_00264	1.06e-276	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NBNEAFNA_00265	2.39e-64	-	-	-	-	-	-	-	-
NBNEAFNA_00267	2.32e-62	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NBNEAFNA_00268	6.58e-74	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
NBNEAFNA_00269	7.15e-26	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
NBNEAFNA_00270	6.53e-170	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
NBNEAFNA_00271	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
NBNEAFNA_00272	7.68e-254	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NBNEAFNA_00273	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NBNEAFNA_00274	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
NBNEAFNA_00275	1.46e-117	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NBNEAFNA_00276	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NBNEAFNA_00277	1.97e-60	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NBNEAFNA_00278	4.92e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NBNEAFNA_00279	4.67e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
NBNEAFNA_00280	1.83e-148	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NBNEAFNA_00281	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
NBNEAFNA_00282	1.38e-230	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NBNEAFNA_00283	3.71e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
NBNEAFNA_00284	4.69e-202	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NBNEAFNA_00285	9.68e-173	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
NBNEAFNA_00286	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NBNEAFNA_00287	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NBNEAFNA_00288	1.21e-217	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NBNEAFNA_00289	2.35e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NBNEAFNA_00290	7.04e-160	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
NBNEAFNA_00291	4.12e-133	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
NBNEAFNA_00292	2.77e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NBNEAFNA_00293	1.41e-167	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NBNEAFNA_00294	4.74e-286	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NBNEAFNA_00295	2.46e-175	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NBNEAFNA_00296	1.43e-178	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
NBNEAFNA_00297	2.84e-285	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NBNEAFNA_00298	4.34e-235	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NBNEAFNA_00299	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
NBNEAFNA_00300	4.67e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NBNEAFNA_00301	5.25e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NBNEAFNA_00302	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NBNEAFNA_00303	6.34e-27	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
NBNEAFNA_00304	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
NBNEAFNA_00305	7.83e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
NBNEAFNA_00306	8.67e-122	dpsB	-	-	P	-	-	-	Belongs to the Dps family
NBNEAFNA_00307	5.63e-145	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
NBNEAFNA_00308	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NBNEAFNA_00309	1.5e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
NBNEAFNA_00310	9.29e-220	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NBNEAFNA_00311	7.22e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NBNEAFNA_00312	1.29e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
NBNEAFNA_00313	4.67e-146	yjbH	-	-	Q	-	-	-	Thioredoxin
NBNEAFNA_00314	2.98e-215	-	-	-	-	-	-	-	-
NBNEAFNA_00315	3.95e-127	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NBNEAFNA_00316	6.4e-229	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
NBNEAFNA_00317	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NBNEAFNA_00318	9.72e-156	csrR	-	-	K	-	-	-	response regulator
NBNEAFNA_00319	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NBNEAFNA_00320	4.61e-126	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
NBNEAFNA_00324	5.68e-08	-	-	-	-	-	-	-	-
NBNEAFNA_00325	1.25e-17	-	-	-	-	-	-	-	-
NBNEAFNA_00328	2.28e-10	-	-	-	L	-	-	-	Transposase
NBNEAFNA_00329	9.74e-99	-	-	-	L	-	-	-	Helix-turn-helix domain
NBNEAFNA_00330	8.45e-202	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
NBNEAFNA_00331	1.2e-168	-	-	-	L	-	-	-	PFAM Integrase, catalytic core
NBNEAFNA_00332	6.2e-84	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
NBNEAFNA_00333	1.74e-60	-	-	-	-	-	-	-	-
NBNEAFNA_00334	4.32e-30	-	-	-	S	-	-	-	PFAM Archaeal ATPase
NBNEAFNA_00335	4.82e-221	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NBNEAFNA_00336	8.17e-316	-	-	-	E	ko:K03294	-	ko00000	amino acid
NBNEAFNA_00337	4.68e-233	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NBNEAFNA_00338	4.58e-109	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
NBNEAFNA_00339	2.7e-155	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NBNEAFNA_00340	1.37e-86	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NBNEAFNA_00341	1.31e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
NBNEAFNA_00342	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NBNEAFNA_00343	1.31e-265	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NBNEAFNA_00344	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
NBNEAFNA_00345	2.71e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NBNEAFNA_00346	3.23e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NBNEAFNA_00347	3.09e-85	-	-	-	-	-	-	-	-
NBNEAFNA_00348	6.32e-225	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
NBNEAFNA_00349	1.16e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NBNEAFNA_00350	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NBNEAFNA_00351	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NBNEAFNA_00352	1.96e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
NBNEAFNA_00353	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
NBNEAFNA_00354	2.78e-273	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
NBNEAFNA_00355	2.59e-107	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
NBNEAFNA_00356	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NBNEAFNA_00357	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NBNEAFNA_00358	6.65e-298	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
NBNEAFNA_00359	2.03e-178	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
NBNEAFNA_00360	2.13e-181	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NBNEAFNA_00361	8.54e-123	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NBNEAFNA_00362	3.66e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
NBNEAFNA_00363	2.58e-196	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NBNEAFNA_00364	3.54e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
NBNEAFNA_00365	7.7e-229	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBNEAFNA_00366	5.59e-64	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
NBNEAFNA_00367	1.98e-180	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
NBNEAFNA_00368	1.52e-151	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
NBNEAFNA_00369	1.72e-39	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
NBNEAFNA_00370	1.1e-46	ynzC	-	-	S	-	-	-	UPF0291 protein
NBNEAFNA_00371	2.07e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NBNEAFNA_00372	4.56e-267	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
NBNEAFNA_00373	5.08e-164	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NBNEAFNA_00377	1.91e-144	-	-	-	K	-	-	-	Transcriptional regulator
NBNEAFNA_00378	1.01e-196	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
NBNEAFNA_00379	2.79e-164	-	-	-	L	-	-	-	Helix-turn-helix domain
NBNEAFNA_00380	1.98e-202	-	-	-	-	-	-	-	-
NBNEAFNA_00381	2.38e-229	-	-	-	-	-	-	-	-
NBNEAFNA_00382	6.45e-111	-	-	-	S	-	-	-	Protein conserved in bacteria
NBNEAFNA_00383	6.12e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF1071)
NBNEAFNA_00384	1.54e-91	-	-	-	S	-	-	-	Putative HNHc nuclease
NBNEAFNA_00385	2.65e-23	-	-	-	S	-	-	-	HNH endonuclease
NBNEAFNA_00386	4.98e-27	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
NBNEAFNA_00388	8.69e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NBNEAFNA_00389	1.26e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
NBNEAFNA_00390	1.34e-127	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
NBNEAFNA_00392	2.66e-35	-	-	-	-	-	-	-	-
NBNEAFNA_00393	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NBNEAFNA_00394	1.93e-150	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
NBNEAFNA_00395	3.42e-41	-	-	-	S	-	-	-	Transglycosylase associated protein
NBNEAFNA_00396	4.74e-23	-	-	-	-	-	-	-	-
NBNEAFNA_00397	2.24e-17	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NBNEAFNA_00398	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
NBNEAFNA_00399	2.61e-73	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
NBNEAFNA_00400	2.83e-91	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
NBNEAFNA_00401	5.31e-115	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NBNEAFNA_00403	8.22e-288	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
NBNEAFNA_00404	8.23e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
NBNEAFNA_00406	5.62e-93	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
NBNEAFNA_00408	4.08e-39	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
NBNEAFNA_00410	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NBNEAFNA_00411	7.79e-237	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
NBNEAFNA_00412	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NBNEAFNA_00413	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NBNEAFNA_00414	2.26e-65	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NBNEAFNA_00415	1.11e-260	camS	-	-	S	-	-	-	sex pheromone
NBNEAFNA_00416	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NBNEAFNA_00417	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
NBNEAFNA_00418	1.32e-271	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NBNEAFNA_00419	7.9e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NBNEAFNA_00420	5.95e-147	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
NBNEAFNA_00421	1.56e-180	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
NBNEAFNA_00422	3.24e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
NBNEAFNA_00423	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NBNEAFNA_00424	2.05e-180	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NBNEAFNA_00425	2.77e-179	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NBNEAFNA_00426	3.8e-194	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NBNEAFNA_00427	7.08e-186	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NBNEAFNA_00428	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
NBNEAFNA_00429	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NBNEAFNA_00430	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NBNEAFNA_00431	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NBNEAFNA_00432	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
NBNEAFNA_00433	2.41e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NBNEAFNA_00434	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NBNEAFNA_00435	2.88e-306	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NBNEAFNA_00436	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NBNEAFNA_00437	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
NBNEAFNA_00438	2.43e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NBNEAFNA_00439	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NBNEAFNA_00440	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NBNEAFNA_00441	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NBNEAFNA_00442	4.97e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NBNEAFNA_00443	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NBNEAFNA_00444	2.58e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NBNEAFNA_00445	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NBNEAFNA_00446	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NBNEAFNA_00447	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
NBNEAFNA_00448	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NBNEAFNA_00449	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NBNEAFNA_00450	4.36e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NBNEAFNA_00451	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NBNEAFNA_00452	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NBNEAFNA_00453	7.29e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NBNEAFNA_00454	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
NBNEAFNA_00455	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NBNEAFNA_00456	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
NBNEAFNA_00457	0.0	-	-	-	O	-	-	-	Arylsulfotransferase (ASST)
NBNEAFNA_00458	1.94e-05	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
NBNEAFNA_00459	1.48e-293	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
NBNEAFNA_00460	9.97e-27	-	-	-	T	-	-	-	Universal stress protein family
NBNEAFNA_00461	3.53e-232	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
NBNEAFNA_00462	6.63e-232	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
NBNEAFNA_00463	3.42e-41	-	-	-	S	-	-	-	Transglycosylase associated protein
NBNEAFNA_00464	4.74e-23	-	-	-	-	-	-	-	-
NBNEAFNA_00465	2.11e-45	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NBNEAFNA_00466	7.06e-146	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NBNEAFNA_00469	7.98e-42	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
NBNEAFNA_00472	4.18e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
NBNEAFNA_00473	4.53e-212	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NBNEAFNA_00474	1.02e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NBNEAFNA_00494	1.79e-33	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NBNEAFNA_00496	2.96e-52	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
NBNEAFNA_00497	5.51e-54	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
NBNEAFNA_00498	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NBNEAFNA_00499	2.05e-164	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
NBNEAFNA_00500	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NBNEAFNA_00501	3.56e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NBNEAFNA_00502	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
NBNEAFNA_00503	6.72e-111	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
NBNEAFNA_00505	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
NBNEAFNA_00506	1.57e-236	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
NBNEAFNA_00507	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
NBNEAFNA_00508	3.04e-172	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NBNEAFNA_00509	6.27e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NBNEAFNA_00510	1.43e-272	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NBNEAFNA_00511	3.36e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NBNEAFNA_00512	1.43e-172	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NBNEAFNA_00513	2.89e-179	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
NBNEAFNA_00514	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NBNEAFNA_00515	2.5e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NBNEAFNA_00516	4.04e-67	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
NBNEAFNA_00517	8.07e-128	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
NBNEAFNA_00518	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NBNEAFNA_00519	5.98e-265	yacL	-	-	S	-	-	-	domain protein
NBNEAFNA_00520	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NBNEAFNA_00521	8.79e-94	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NBNEAFNA_00522	7.41e-175	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NBNEAFNA_00523	9.18e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NBNEAFNA_00524	7.11e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NBNEAFNA_00525	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NBNEAFNA_00526	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NBNEAFNA_00527	3.39e-157	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NBNEAFNA_00528	9.63e-291	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
NBNEAFNA_00530	8.22e-306	-	-	-	M	-	-	-	Glycosyl transferase family group 2
NBNEAFNA_00531	6.52e-270	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NBNEAFNA_00532	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NBNEAFNA_00533	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NBNEAFNA_00534	1.2e-262	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NBNEAFNA_00535	4.35e-26	-	-	-	-	-	-	-	-
NBNEAFNA_00536	1.03e-97	-	-	-	P	-	-	-	Major Facilitator Superfamily
NBNEAFNA_00537	2.96e-90	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
NBNEAFNA_00538	8.61e-168	-	-	-	IQ	-	-	-	dehydrogenase reductase
NBNEAFNA_00539	1.15e-82	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
NBNEAFNA_00540	1.8e-115	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
NBNEAFNA_00542	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
NBNEAFNA_00543	2.02e-149	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NBNEAFNA_00544	1.78e-42	-	-	-	-	-	-	-	-
NBNEAFNA_00545	1.41e-68	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
NBNEAFNA_00547	8.57e-08	-	-	-	N	-	-	-	S-layer homology domain
NBNEAFNA_00549	1.39e-63	-	-	-	S	-	-	-	Double zinc ribbon
NBNEAFNA_00550	3.14e-229	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
NBNEAFNA_00551	6.65e-234	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
NBNEAFNA_00552	1.1e-177	-	-	-	IQ	-	-	-	KR domain
NBNEAFNA_00553	8.5e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NBNEAFNA_00554	3.5e-126	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
NBNEAFNA_00555	7.1e-309	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NBNEAFNA_00556	9.34e-144	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
NBNEAFNA_00557	5.35e-70	-	-	-	-	-	-	-	-
NBNEAFNA_00558	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
NBNEAFNA_00559	1.82e-68	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
NBNEAFNA_00560	1.71e-239	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
NBNEAFNA_00561	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
NBNEAFNA_00562	1.35e-204	-	-	-	-	-	-	-	-
NBNEAFNA_00563	2.28e-41	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
NBNEAFNA_00564	5e-41	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
NBNEAFNA_00565	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
NBNEAFNA_00566	1.08e-267	-	-	-	EGP	-	-	-	Major Facilitator
NBNEAFNA_00567	4.36e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NBNEAFNA_00568	3.35e-12	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
NBNEAFNA_00569	3.96e-58	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
NBNEAFNA_00570	4.39e-11	-	-	-	-	-	-	-	-
NBNEAFNA_00571	1.78e-83	-	-	-	-	-	-	-	-
NBNEAFNA_00572	4.97e-249	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
NBNEAFNA_00573	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
NBNEAFNA_00574	3.96e-65	fusA1	-	-	J	-	-	-	elongation factor G
NBNEAFNA_00575	0.0	fusA1	-	-	J	-	-	-	elongation factor G
NBNEAFNA_00576	1.47e-211	-	-	-	GK	-	-	-	ROK family
NBNEAFNA_00577	1.8e-306	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NBNEAFNA_00578	1.02e-176	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
NBNEAFNA_00579	2.77e-306	-	-	-	E	-	-	-	amino acid
NBNEAFNA_00582	2.68e-05	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NBNEAFNA_00584	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NBNEAFNA_00585	2.2e-61	-	-	-	-	-	-	-	-
NBNEAFNA_00586	1.29e-88	-	-	-	S	-	-	-	PFAM Archaeal ATPase
NBNEAFNA_00587	1.14e-107	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
NBNEAFNA_00588	3.04e-71	-	-	-	-	-	-	-	-
NBNEAFNA_00589	4.41e-27	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NBNEAFNA_00590	1.81e-30	comA	-	-	V	ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NBNEAFNA_00591	1.04e-209	-	-	-	S	-	-	-	reductase
NBNEAFNA_00592	5.72e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NBNEAFNA_00593	2.83e-104	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
NBNEAFNA_00594	1.9e-202	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
NBNEAFNA_00595	4.28e-197	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
NBNEAFNA_00596	1.78e-191	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
NBNEAFNA_00605	3.08e-165	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
NBNEAFNA_00606	3.26e-178	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
NBNEAFNA_00607	1.98e-182	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NBNEAFNA_00608	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
NBNEAFNA_00609	5.61e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NBNEAFNA_00610	4.19e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NBNEAFNA_00611	5.75e-285	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NBNEAFNA_00612	4.98e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
NBNEAFNA_00613	6.27e-200	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
NBNEAFNA_00614	7.21e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NBNEAFNA_00615	1.36e-219	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NBNEAFNA_00616	2.35e-101	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
NBNEAFNA_00617	1.76e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NBNEAFNA_00619	1.19e-258	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NBNEAFNA_00620	2.7e-39	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
NBNEAFNA_00621	5.69e-234	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
NBNEAFNA_00622	2.42e-202	rssA	-	-	S	-	-	-	Phospholipase, patatin family
NBNEAFNA_00623	1.15e-152	-	-	-	L	-	-	-	Integrase
NBNEAFNA_00624	0.0	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
NBNEAFNA_00625	6.11e-68	-	-	-	-	-	-	-	-
NBNEAFNA_00626	2.37e-181	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NBNEAFNA_00627	2.76e-190	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NBNEAFNA_00628	3.17e-150	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NBNEAFNA_00629	1.38e-292	-	-	-	P	-	-	-	Chloride transporter, ClC family
NBNEAFNA_00630	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
NBNEAFNA_00631	6.88e-144	-	-	-	I	-	-	-	Acid phosphatase homologues
NBNEAFNA_00633	4.72e-13	-	-	-	K	-	-	-	Transcriptional regulator
NBNEAFNA_00634	2.01e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
NBNEAFNA_00636	3.05e-91	-	-	-	L	-	-	-	Bacterial dnaA protein
NBNEAFNA_00637	2.06e-49	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
NBNEAFNA_00638	3.82e-90	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NBNEAFNA_00639	7.53e-99	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NBNEAFNA_00640	4.11e-100	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
NBNEAFNA_00641	2.3e-51	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
NBNEAFNA_00645	1.02e-62	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
NBNEAFNA_00647	7.19e-50	-	-	-	-	-	-	-	-
NBNEAFNA_00649	1.22e-112	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
NBNEAFNA_00650	1.48e-246	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NBNEAFNA_00651	7.95e-272	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
NBNEAFNA_00652	5.73e-216	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
NBNEAFNA_00653	1.36e-215	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
NBNEAFNA_00654	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
NBNEAFNA_00655	2.61e-112	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
NBNEAFNA_00656	3.24e-157	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
NBNEAFNA_00657	2.42e-208	-	-	-	EG	-	-	-	EamA-like transporter family
NBNEAFNA_00658	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
NBNEAFNA_00659	7.01e-153	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NBNEAFNA_00660	7.96e-129	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
NBNEAFNA_00661	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NBNEAFNA_00662	1.18e-108	-	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
NBNEAFNA_00663	5.69e-281	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
NBNEAFNA_00664	5.19e-90	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
NBNEAFNA_00665	2.58e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
NBNEAFNA_00666	7.28e-96	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NBNEAFNA_00667	5.85e-224	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NBNEAFNA_00668	7.52e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
NBNEAFNA_00669	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
NBNEAFNA_00670	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
NBNEAFNA_00671	9.88e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
NBNEAFNA_00672	2.62e-124	-	-	-	-	-	-	-	-
NBNEAFNA_00673	3.33e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
NBNEAFNA_00675	9.24e-122	-	-	-	-	-	-	-	-
NBNEAFNA_00676	7.98e-42	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
NBNEAFNA_00680	5.44e-34	-	-	-	S	-	-	-	Transglycosylase associated protein
NBNEAFNA_00683	3.47e-240	-	-	-	-	-	-	-	-
NBNEAFNA_00684	1.08e-189	-	-	-	-	-	-	-	-
NBNEAFNA_00685	0.0	-	-	-	-	-	-	-	-
NBNEAFNA_00686	6.82e-159	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NBNEAFNA_00687	2.77e-133	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
NBNEAFNA_00688	5.24e-92	-	-	-	-	-	-	-	-
NBNEAFNA_00689	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NBNEAFNA_00690	4.83e-134	-	-	-	L	-	-	-	nuclease
NBNEAFNA_00691	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
NBNEAFNA_00692	4.55e-265	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NBNEAFNA_00693	4.4e-119	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NBNEAFNA_00694	1.75e-182	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
NBNEAFNA_00695	0.0	snf	-	-	KL	-	-	-	domain protein
NBNEAFNA_00697	5.36e-27	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
NBNEAFNA_00699	6.75e-99	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
NBNEAFNA_00701	5.98e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
NBNEAFNA_00702	1.2e-59	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
NBNEAFNA_00703	3.1e-06	uvrA2	-	-	L	-	-	-	ABC transporter
NBNEAFNA_00704	1.53e-122	-	-	-	-	-	-	-	-
NBNEAFNA_00705	1.25e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NBNEAFNA_00706	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
NBNEAFNA_00707	1.84e-198	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
NBNEAFNA_00708	2.39e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NBNEAFNA_00709	1.9e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NBNEAFNA_00710	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NBNEAFNA_00711	2.44e-20	-	-	-	-	-	-	-	-
NBNEAFNA_00712	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
NBNEAFNA_00713	8.21e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
NBNEAFNA_00714	5.9e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NBNEAFNA_00715	1.85e-301	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NBNEAFNA_00716	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NBNEAFNA_00717	8.43e-207	-	-	-	S	-	-	-	Tetratricopeptide repeat
NBNEAFNA_00718	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NBNEAFNA_00719	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NBNEAFNA_00720	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
NBNEAFNA_00721	3.61e-190	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
NBNEAFNA_00722	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
NBNEAFNA_00723	8.3e-115	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
NBNEAFNA_00724	1.14e-136	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
NBNEAFNA_00725	1.74e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
NBNEAFNA_00726	1.76e-115	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NBNEAFNA_00727	2.37e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
NBNEAFNA_00728	5.25e-59	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
NBNEAFNA_00729	9.19e-285	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NBNEAFNA_00730	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
NBNEAFNA_00731	2.37e-175	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
NBNEAFNA_00732	7.04e-63	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
NBNEAFNA_00733	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
NBNEAFNA_00734	3.53e-310	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NBNEAFNA_00735	1.9e-231	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
NBNEAFNA_00736	9.95e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
NBNEAFNA_00737	1.68e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NBNEAFNA_00738	2.3e-106	-	-	-	-	-	-	-	-
NBNEAFNA_00739	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
NBNEAFNA_00740	7.47e-233	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
NBNEAFNA_00741	8.83e-39	-	-	-	-	-	-	-	-
NBNEAFNA_00742	1.66e-247	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
NBNEAFNA_00744	2.51e-74	-	-	-	-	-	-	-	-
NBNEAFNA_00745	1.86e-64	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
NBNEAFNA_00746	7.41e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NBNEAFNA_00747	3.82e-275	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NBNEAFNA_00748	1.05e-179	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NBNEAFNA_00749	2.11e-219	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NBNEAFNA_00750	6.66e-283	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NBNEAFNA_00751	1.03e-108	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NBNEAFNA_00752	7.68e-310	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NBNEAFNA_00753	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NBNEAFNA_00754	1.57e-219	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NBNEAFNA_00755	3.19e-67	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NBNEAFNA_00756	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NBNEAFNA_00757	1.72e-305	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NBNEAFNA_00758	2.69e-234	-	-	-	-	-	-	-	-
NBNEAFNA_00759	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NBNEAFNA_00760	9.62e-309	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
NBNEAFNA_00761	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
NBNEAFNA_00762	1.37e-134	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NBNEAFNA_00763	2.01e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
NBNEAFNA_00764	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NBNEAFNA_00765	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NBNEAFNA_00766	3.84e-161	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NBNEAFNA_00767	6.39e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NBNEAFNA_00768	4.82e-166	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
NBNEAFNA_00769	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NBNEAFNA_00770	5.14e-268	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NBNEAFNA_00771	8.95e-110	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NBNEAFNA_00772	2.3e-168	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
NBNEAFNA_00773	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
NBNEAFNA_00774	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
NBNEAFNA_00775	3.55e-221	ydbI	-	-	K	-	-	-	AI-2E family transporter
NBNEAFNA_00776	2.01e-289	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
NBNEAFNA_00778	7.38e-225	ydhF	-	-	S	-	-	-	Aldo keto reductase
NBNEAFNA_00779	3.45e-105	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
NBNEAFNA_00780	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
NBNEAFNA_00782	3.67e-311	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
NBNEAFNA_00783	1.85e-69	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
NBNEAFNA_00784	2.04e-160	-	-	-	-	-	-	-	-
NBNEAFNA_00785	1.74e-166	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
NBNEAFNA_00786	0.0	cadA	-	-	P	-	-	-	P-type ATPase
NBNEAFNA_00787	1.04e-268	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
NBNEAFNA_00788	7.65e-12	-	-	-	-	-	-	-	-
NBNEAFNA_00789	3.78e-157	-	-	-	GM	-	-	-	NAD(P)H-binding
NBNEAFNA_00790	3.31e-98	ywnA	-	-	K	-	-	-	Transcriptional regulator
NBNEAFNA_00791	5.93e-206	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
NBNEAFNA_00792	4.74e-139	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NBNEAFNA_00793	6.85e-179	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NBNEAFNA_00794	6.56e-137	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
NBNEAFNA_00795	1.05e-101	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
NBNEAFNA_00796	9.12e-139	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NBNEAFNA_00797	2.8e-143	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NBNEAFNA_00798	8.7e-279	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
NBNEAFNA_00799	2.14e-139	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NBNEAFNA_00800	1.04e-245	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NBNEAFNA_00801	1.02e-198	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NBNEAFNA_00802	7.92e-30	-	-	-	S	-	-	-	cog cog1302
NBNEAFNA_00804	9.99e-83	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NBNEAFNA_00805	4.34e-261	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
NBNEAFNA_00806	1.98e-203	-	-	-	K	-	-	-	LysR substrate binding domain
NBNEAFNA_00807	1.57e-123	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
NBNEAFNA_00808	2.71e-125	-	-	-	K	-	-	-	acetyltransferase
NBNEAFNA_00809	1.41e-239	-	-	-	-	-	-	-	-
NBNEAFNA_00811	2.2e-39	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
NBNEAFNA_00812	2.68e-216	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
NBNEAFNA_00813	8.47e-127	-	-	-	S	-	-	-	AmiS/UreI family transporter
NBNEAFNA_00814	1.66e-55	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease, gamma subunit
NBNEAFNA_00815	7.81e-82	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease beta subunit
NBNEAFNA_00816	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Amidohydrolase family
NBNEAFNA_00817	3.08e-102	ureE	-	-	O	ko:K03187	-	ko00000	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NBNEAFNA_00818	2.02e-162	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NBNEAFNA_00819	8.11e-145	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NBNEAFNA_00820	1.07e-205	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NBNEAFNA_00821	1.61e-229	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
NBNEAFNA_00822	9.97e-185	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
NBNEAFNA_00823	5.23e-171	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NBNEAFNA_00824	1.46e-133	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
NBNEAFNA_00825	8.59e-161	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
NBNEAFNA_00826	2.17e-192	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NBNEAFNA_00827	5.44e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
NBNEAFNA_00828	9.02e-177	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NBNEAFNA_00829	3.52e-161	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
NBNEAFNA_00831	8.05e-146	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NBNEAFNA_00832	7.58e-251	-	-	-	M	-	-	-	Prophage endopeptidase tail
NBNEAFNA_00833	2.51e-130	-	-	-	S	-	-	-	Phage tail protein
NBNEAFNA_00834	0.0	-	-	-	D	-	-	-	domain protein
NBNEAFNA_00837	4.23e-105	-	-	-	-	-	-	-	-
NBNEAFNA_00838	4.81e-55	-	-	-	-	-	-	-	-
NBNEAFNA_00839	5.3e-83	-	-	-	-	-	-	-	-
NBNEAFNA_00840	1.74e-38	-	-	-	-	-	-	-	-
NBNEAFNA_00841	1.14e-61	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
NBNEAFNA_00842	4.1e-182	-	-	-	-	-	-	-	-
NBNEAFNA_00843	1.57e-68	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
NBNEAFNA_00845	2.37e-133	-	-	-	S	-	-	-	Phage Mu protein F like protein
NBNEAFNA_00846	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
NBNEAFNA_00847	1.68e-214	-	-	-	S	-	-	-	Terminase-like family
NBNEAFNA_00848	7.51e-80	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
NBNEAFNA_00849	1.03e-114	-	-	-	L	-	-	-	DNA methylase
NBNEAFNA_00852	6.34e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
NBNEAFNA_00853	6.46e-45	glnA	6.3.1.2	-	F	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamine synthetase, catalytic domain
NBNEAFNA_00855	8.81e-169	-	-	-	K	-	-	-	LysR substrate binding domain
NBNEAFNA_00856	3.33e-69	-	-	-	S	-	-	-	branched-chain amino acid
NBNEAFNA_00857	1.97e-185	-	-	-	E	-	-	-	AzlC protein
NBNEAFNA_00858	2.63e-264	hpk31	-	-	T	-	-	-	Histidine kinase
NBNEAFNA_00859	9.76e-161	vanR	-	-	K	-	-	-	response regulator
NBNEAFNA_00860	6.97e-264	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NBNEAFNA_00861	3.92e-217	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
NBNEAFNA_00862	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
NBNEAFNA_00863	5.5e-299	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
NBNEAFNA_00864	3.97e-299	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NBNEAFNA_00865	9.74e-154	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NBNEAFNA_00866	1.66e-170	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
NBNEAFNA_00867	5.01e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NBNEAFNA_00868	5.8e-43	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
NBNEAFNA_00869	2.79e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NBNEAFNA_00870	2.79e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
NBNEAFNA_00871	1.39e-195	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NBNEAFNA_00872	8.56e-161	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
NBNEAFNA_00873	4.38e-210	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
NBNEAFNA_00874	3.5e-220	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
NBNEAFNA_00875	1.97e-277	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
NBNEAFNA_00876	0.0	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
NBNEAFNA_00877	1.31e-232	yueF	-	-	S	-	-	-	AI-2E family transporter
NBNEAFNA_00878	2.65e-298	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NBNEAFNA_00879	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NBNEAFNA_00880	2.53e-26	-	-	-	M	-	-	-	NlpC/P60 family
NBNEAFNA_00881	0.0	-	-	-	M	-	-	-	NlpC/P60 family
NBNEAFNA_00882	0.0	-	-	-	S	-	-	-	Peptidase, M23
NBNEAFNA_00883	0.0	-	-	-	S	-	-	-	Peptidase, M23
NBNEAFNA_00884	1.7e-84	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
NBNEAFNA_00885	1.91e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NBNEAFNA_00886	5.78e-148	-	-	-	-	-	-	-	-
NBNEAFNA_00887	1.35e-182	-	-	-	G	-	-	-	MucBP domain
NBNEAFNA_00888	3.15e-130	-	-	-	S	-	-	-	Pfam:DUF3816
NBNEAFNA_00889	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
NBNEAFNA_00890	1.38e-37	-	-	-	-	-	-	-	-
NBNEAFNA_00891	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
NBNEAFNA_00892	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NBNEAFNA_00893	9.83e-18	-	-	-	S	-	-	-	Small integral membrane protein (DUF2273)
NBNEAFNA_00894	7.17e-20	-	-	-	S	-	-	-	Small integral membrane protein (DUF2273)
NBNEAFNA_00895	1.54e-79	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
NBNEAFNA_00896	9.34e-225	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NBNEAFNA_00897	1.93e-161	-	-	-	L	-	-	-	Type I restriction modification DNA specificity domain
NBNEAFNA_00898	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
NBNEAFNA_00899	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
NBNEAFNA_00900	4.26e-178	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
NBNEAFNA_00901	3.31e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
NBNEAFNA_00902	1.26e-60	-	-	-	-	-	-	-	-
NBNEAFNA_00903	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
NBNEAFNA_00904	3.8e-63	-	-	-	-	-	-	-	-
NBNEAFNA_00905	4.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NBNEAFNA_00906	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
NBNEAFNA_00907	5.67e-297	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
NBNEAFNA_00908	4.12e-234	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
NBNEAFNA_00909	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
NBNEAFNA_00910	6.59e-124	-	-	-	-	-	-	-	-
NBNEAFNA_00911	3.61e-34	-	-	-	-	-	-	-	-
NBNEAFNA_00912	5.16e-72	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NBNEAFNA_00913	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
NBNEAFNA_00914	3.39e-157	-	-	-	S	-	-	-	SNARE associated Golgi protein
NBNEAFNA_00915	9.36e-294	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
NBNEAFNA_00916	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NBNEAFNA_00918	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
NBNEAFNA_00919	5.47e-199	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
NBNEAFNA_00920	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NBNEAFNA_00921	9.73e-55	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
NBNEAFNA_00922	6.49e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
NBNEAFNA_00923	1.7e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
NBNEAFNA_00924	1.47e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NBNEAFNA_00925	1.15e-25	-	-	-	-	-	-	-	-
NBNEAFNA_00926	1.14e-116	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
NBNEAFNA_00927	9.68e-193	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
NBNEAFNA_00928	1.1e-57	yrvD	-	-	S	-	-	-	Pfam:DUF1049
NBNEAFNA_00930	2.92e-14	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
NBNEAFNA_00931	7.69e-06	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NBNEAFNA_00932	1.7e-06	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NBNEAFNA_00933	2.51e-209	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NBNEAFNA_00936	2.29e-30	-	-	-	M	-	-	-	CHAP domain
NBNEAFNA_00938	3.02e-123	-	-	-	S	-	-	-	peptidoglycan catabolic process
NBNEAFNA_00939	6.68e-46	-	-	-	S	-	-	-	Bacteriophage Gp15 protein
NBNEAFNA_00941	3.7e-51	-	-	-	N	-	-	-	domain, Protein
NBNEAFNA_00944	3.07e-38	-	-	-	S	-	-	-	Minor capsid protein
NBNEAFNA_00946	2.86e-131	-	-	-	-	-	-	-	-
NBNEAFNA_00947	6.52e-17	-	-	-	S	-	-	-	Phage minor structural protein GP20
NBNEAFNA_00948	2.8e-114	-	-	-	S	-	-	-	Phage minor capsid protein 2
NBNEAFNA_00949	1.26e-164	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
NBNEAFNA_00950	2.5e-172	-	-	-	S	-	-	-	Pfam:Terminase_3C
NBNEAFNA_00951	1.24e-60	-	-	-	-	-	-	-	-
NBNEAFNA_00953	1.75e-33	-	-	-	-	-	-	-	-
NBNEAFNA_00954	2.09e-86	-	-	-	K	-	-	-	Protein of unknown function (DUF4065)
NBNEAFNA_00955	7.22e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NBNEAFNA_00956	9.72e-185	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NBNEAFNA_00957	6.29e-183	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NBNEAFNA_00958	3.46e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NBNEAFNA_00959	2.86e-138	-	-	-	-	-	-	-	-
NBNEAFNA_00960	2.16e-88	-	-	-	-	-	-	-	-
NBNEAFNA_00961	4.44e-292	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
NBNEAFNA_00962	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
NBNEAFNA_00963	2.53e-97	-	-	-	F	-	-	-	Nudix hydrolase
NBNEAFNA_00964	1.17e-126	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
NBNEAFNA_00965	1.22e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
NBNEAFNA_00966	1.77e-33	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
NBNEAFNA_00967	1.98e-194	-	-	-	-	-	-	-	-
NBNEAFNA_00968	6.09e-53	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
NBNEAFNA_00969	6.12e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
NBNEAFNA_00970	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
NBNEAFNA_00971	8.03e-231	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBNEAFNA_00972	1.85e-09	-	-	-	S	-	-	-	CsbD-like
NBNEAFNA_00973	1.98e-42	-	-	-	S	-	-	-	Transglycosylase associated protein
NBNEAFNA_00974	6.71e-67	-	-	-	L	-	-	-	PFAM Integrase catalytic region
NBNEAFNA_00977	2.26e-130	-	-	-	-	-	-	-	-
NBNEAFNA_00978	6.68e-14	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NBNEAFNA_00979	2.5e-243	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NBNEAFNA_00980	6.69e-168	-	-	-	S	-	-	-	Alpha beta hydrolase
NBNEAFNA_00981	9.11e-261	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
NBNEAFNA_00982	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NBNEAFNA_00983	7.2e-56	-	-	-	-	-	-	-	-
NBNEAFNA_00984	1.64e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
NBNEAFNA_00985	3.12e-193	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
NBNEAFNA_00986	4.97e-115	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
NBNEAFNA_00987	5.67e-315	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
NBNEAFNA_00988	4.79e-307	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
NBNEAFNA_00989	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NBNEAFNA_00990	1.52e-211	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NBNEAFNA_00991	4.92e-213	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
NBNEAFNA_00992	1.08e-168	yceF	-	-	P	ko:K05794	-	ko00000	membrane
NBNEAFNA_00993	6.22e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NBNEAFNA_00994	4.19e-300	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
NBNEAFNA_00995	1.33e-73	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
NBNEAFNA_00996	4.74e-120	-	-	-	P	-	-	-	Cadmium resistance transporter
NBNEAFNA_00997	2.11e-172	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NBNEAFNA_00998	6.8e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NBNEAFNA_00999	3.69e-232	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
NBNEAFNA_01000	6.32e-171	-	-	-	M	-	-	-	PFAM NLP P60 protein
NBNEAFNA_01001	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
NBNEAFNA_01002	7.71e-182	-	-	-	S	-	-	-	Putative ABC-transporter type IV
NBNEAFNA_01003	6.99e-136	-	-	-	NU	-	-	-	mannosyl-glycoprotein
NBNEAFNA_01004	9.02e-317	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NBNEAFNA_01005	4.27e-292	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
NBNEAFNA_01006	3.42e-258	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
NBNEAFNA_01007	2.48e-66	-	-	-	-	-	-	-	-
NBNEAFNA_01008	1.25e-28	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
NBNEAFNA_01009	1.76e-12	-	2.1.1.72	-	D	ko:K03427	-	ko00000,ko01000,ko02048	peptidase
NBNEAFNA_01011	3.32e-72	-	-	-	-	-	-	-	-
NBNEAFNA_01012	2.37e-151	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
NBNEAFNA_01014	2.63e-84	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
NBNEAFNA_01015	1.11e-152	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
NBNEAFNA_01016	1.98e-259	-	-	-	S	-	-	-	associated with various cellular activities
NBNEAFNA_01017	2.5e-296	-	-	-	S	-	-	-	Putative metallopeptidase domain
NBNEAFNA_01018	1.48e-64	-	-	-	-	-	-	-	-
NBNEAFNA_01019	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
NBNEAFNA_01020	2.49e-141	-	-	-	K	-	-	-	Helix-turn-helix domain
NBNEAFNA_01021	3.1e-115	ymdB	-	-	S	-	-	-	Macro domain protein
NBNEAFNA_01022	4.31e-33	-	-	-	EGP	-	-	-	Major Facilitator
NBNEAFNA_01023	1.29e-199	-	-	-	EGP	-	-	-	Major Facilitator
NBNEAFNA_01024	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NBNEAFNA_01025	2.16e-212	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NBNEAFNA_01026	1.16e-200	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
NBNEAFNA_01027	7.6e-286	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NBNEAFNA_01028	3.94e-75	yvgN	-	-	S	-	-	-	Aldo keto reductase
NBNEAFNA_01029	2.39e-176	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
NBNEAFNA_01030	2.25e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NBNEAFNA_01031	4.33e-259	-	-	-	-	-	-	-	-
NBNEAFNA_01032	1.19e-66	-	-	-	-	-	-	-	-
NBNEAFNA_01033	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NBNEAFNA_01034	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
NBNEAFNA_01035	6.36e-34	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
NBNEAFNA_01036	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NBNEAFNA_01037	1.86e-114	-	-	-	-	-	-	-	-
NBNEAFNA_01038	3.96e-49	-	-	-	-	-	-	-	-
NBNEAFNA_01039	1.17e-131	-	-	-	K	-	-	-	DNA-templated transcription, initiation
NBNEAFNA_01040	1.67e-38	-	-	-	-	-	-	-	-
NBNEAFNA_01041	2.98e-78	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
NBNEAFNA_01042	7.26e-267	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
NBNEAFNA_01043	1.7e-118	-	-	-	-	-	-	-	-
NBNEAFNA_01044	1.27e-86	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NBNEAFNA_01045	6.01e-223	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NBNEAFNA_01046	8.47e-186	epsB	-	-	M	-	-	-	biosynthesis protein
NBNEAFNA_01047	2.57e-151	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
NBNEAFNA_01048	4.19e-133	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
NBNEAFNA_01049	7.85e-96	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
NBNEAFNA_01050	4.28e-65	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
NBNEAFNA_01051	1.37e-75	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NBNEAFNA_01052	1.53e-90	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NBNEAFNA_01053	1.12e-24	-	-	-	-	-	-	-	-
NBNEAFNA_01054	2.18e-133	-	-	-	M	-	-	-	LysM domain protein
NBNEAFNA_01055	2.61e-203	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
NBNEAFNA_01056	2.28e-143	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NBNEAFNA_01057	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
NBNEAFNA_01058	2.22e-269	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
NBNEAFNA_01059	9.66e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NBNEAFNA_01060	8.63e-20	-	-	-	E	-	-	-	Zn peptidase
NBNEAFNA_01063	2.05e-83	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
NBNEAFNA_01064	7.15e-197	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
NBNEAFNA_01065	8.32e-188	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
NBNEAFNA_01067	2.56e-249	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
NBNEAFNA_01068	1.92e-204	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
NBNEAFNA_01069	5.33e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NBNEAFNA_01070	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NBNEAFNA_01071	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
NBNEAFNA_01072	8.07e-76	-	-	-	-	-	-	-	-
NBNEAFNA_01075	3.3e-21	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
NBNEAFNA_01076	6.57e-232	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
NBNEAFNA_01077	4.15e-173	-	-	-	S	-	-	-	Phage portal protein
NBNEAFNA_01078	1.24e-251	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
NBNEAFNA_01079	2.63e-33	terS	-	-	L	-	-	-	Phage terminase, small subunit
NBNEAFNA_01080	1.07e-41	-	-	-	L	-	-	-	HNH endonuclease
NBNEAFNA_01084	2.94e-113	-	-	-	S	ko:K06919	-	ko00000	DNA primase
NBNEAFNA_01090	5.17e-64	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NBNEAFNA_01091	2.22e-171	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
NBNEAFNA_01092	0.0	yclK	-	-	T	-	-	-	Histidine kinase
NBNEAFNA_01093	1.29e-198	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
NBNEAFNA_01094	2.74e-94	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
NBNEAFNA_01095	3.88e-12	-	-	-	-	-	-	-	-
NBNEAFNA_01096	5.01e-112	-	-	-	S	-	-	-	Glycosyltransferase like family
NBNEAFNA_01097	1.06e-109	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
NBNEAFNA_01098	2.19e-51	-	-	-	M	-	-	-	biosynthesis protein
NBNEAFNA_01099	2.5e-115	cps3F	-	-	-	-	-	-	-
NBNEAFNA_01100	2.18e-129	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NBNEAFNA_01101	3.64e-140	-	-	-	S	-	-	-	Glycosyltransferase like family 2
NBNEAFNA_01102	4.91e-93	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
NBNEAFNA_01103	4.63e-270	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
NBNEAFNA_01104	2.9e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
NBNEAFNA_01105	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
NBNEAFNA_01106	5.5e-99	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
NBNEAFNA_01107	1.99e-72	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
NBNEAFNA_01108	0.0	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
NBNEAFNA_01109	1.98e-26	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
NBNEAFNA_01110	4.65e-22	-	-	-	-	-	-	-	-
NBNEAFNA_01111	1.43e-95	-	-	-	H	-	-	-	RibD C-terminal domain
NBNEAFNA_01112	9e-39	-	-	-	H	-	-	-	RibD C-terminal domain
NBNEAFNA_01113	4.08e-147	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
NBNEAFNA_01114	2.1e-243	-	-	-	T	-	-	-	GHKL domain
NBNEAFNA_01115	2.84e-55	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
NBNEAFNA_01116	2.57e-109	-	-	-	C	-	-	-	Flavodoxin
NBNEAFNA_01117	3.2e-154	lysR	-	-	K	-	-	-	Transcriptional regulator
NBNEAFNA_01118	4.58e-70	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
NBNEAFNA_01120	9.92e-34	-	-	-	S	-	-	-	Alpha beta hydrolase
NBNEAFNA_01121	3.97e-135	-	-	-	S	-	-	-	Alpha beta hydrolase
NBNEAFNA_01122	3.43e-195	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
NBNEAFNA_01123	6.55e-223	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NBNEAFNA_01124	2.65e-288	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
NBNEAFNA_01125	1.96e-212	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
NBNEAFNA_01126	1.99e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
NBNEAFNA_01127	4.62e-194	-	-	-	K	-	-	-	Transcriptional regulator
NBNEAFNA_01128	1.64e-204	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
NBNEAFNA_01129	9.68e-83	-	-	-	-	-	-	-	-
NBNEAFNA_01130	2.41e-158	-	-	-	F	-	-	-	glutamine amidotransferase
NBNEAFNA_01131	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NBNEAFNA_01132	3.71e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
NBNEAFNA_01133	2.61e-190	ylmH	-	-	S	-	-	-	S4 domain protein
NBNEAFNA_01134	3.2e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
NBNEAFNA_01135	5.27e-91	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NBNEAFNA_01136	6.52e-289	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NBNEAFNA_01137	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NBNEAFNA_01138	6.12e-195	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NBNEAFNA_01139	8.41e-260	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NBNEAFNA_01140	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NBNEAFNA_01141	3.83e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NBNEAFNA_01142	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NBNEAFNA_01143	9.94e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
NBNEAFNA_01144	8.92e-222	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NBNEAFNA_01145	4.29e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
NBNEAFNA_01146	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
NBNEAFNA_01147	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NBNEAFNA_01148	2.42e-64	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
NBNEAFNA_01149	1.92e-284	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
NBNEAFNA_01150	0.0	yhaN	-	-	L	-	-	-	AAA domain
NBNEAFNA_01151	5.8e-176	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NBNEAFNA_01153	3.51e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
NBNEAFNA_01154	4.47e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NBNEAFNA_01155	8.09e-280	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
NBNEAFNA_01156	7.53e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NBNEAFNA_01157	1.01e-38	-	-	-	S	-	-	-	YSIRK type signal peptide
NBNEAFNA_01158	2.48e-125	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
NBNEAFNA_01159	1.98e-196	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NBNEAFNA_01160	6.94e-209	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NBNEAFNA_01161	1.63e-234	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
NBNEAFNA_01162	4.21e-144	-	-	-	-	-	-	-	-
NBNEAFNA_01163	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
NBNEAFNA_01164	3.91e-131	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NBNEAFNA_01165	5.44e-25	-	-	-	K	-	-	-	Transcriptional regulator
NBNEAFNA_01166	6.15e-224	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NBNEAFNA_01167	2.18e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
NBNEAFNA_01168	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
NBNEAFNA_01169	6.85e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NBNEAFNA_01170	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
NBNEAFNA_01171	1.77e-56	-	-	-	-	-	-	-	-
NBNEAFNA_01172	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
NBNEAFNA_01173	6.66e-281	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NBNEAFNA_01174	1.56e-121	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
NBNEAFNA_01175	2.82e-147	-	-	-	M	-	-	-	PFAM NLP P60 protein
NBNEAFNA_01176	2.8e-150	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
NBNEAFNA_01177	3.52e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NBNEAFNA_01178	2.13e-88	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
NBNEAFNA_01179	0.0	-	-	-	S	-	-	-	membrane
NBNEAFNA_01180	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NBNEAFNA_01181	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NBNEAFNA_01182	2.68e-129	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NBNEAFNA_01183	1.66e-138	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
NBNEAFNA_01184	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
NBNEAFNA_01185	1.77e-235	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
NBNEAFNA_01186	1.55e-87	yqhL	-	-	P	-	-	-	Rhodanese-like protein
NBNEAFNA_01187	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
NBNEAFNA_01188	1.88e-222	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NBNEAFNA_01189	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NBNEAFNA_01190	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NBNEAFNA_01191	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
NBNEAFNA_01192	8.82e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NBNEAFNA_01193	1.13e-218	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NBNEAFNA_01194	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NBNEAFNA_01195	8.67e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
NBNEAFNA_01196	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NBNEAFNA_01197	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
NBNEAFNA_01198	4.31e-76	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
NBNEAFNA_01199	5.83e-52	yabO	-	-	J	-	-	-	S4 domain protein
NBNEAFNA_01200	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NBNEAFNA_01201	1.13e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NBNEAFNA_01202	3.29e-146	-	-	-	S	-	-	-	(CBS) domain
NBNEAFNA_01203	1.01e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NBNEAFNA_01204	2.08e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NBNEAFNA_01205	1.33e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
NBNEAFNA_01206	5.75e-141	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
NBNEAFNA_01207	2.45e-216	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
NBNEAFNA_01208	6.38e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
NBNEAFNA_01209	6.1e-143	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
NBNEAFNA_01210	1.09e-115	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NBNEAFNA_01211	7e-245	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NBNEAFNA_01212	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NBNEAFNA_01213	1.16e-285	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NBNEAFNA_01214	5.49e-300	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
NBNEAFNA_01215	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NBNEAFNA_01216	9.51e-317	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
NBNEAFNA_01217	1.49e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
NBNEAFNA_01218	1.55e-152	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
NBNEAFNA_01219	1.31e-55	-	-	-	M	-	-	-	Lysin motif
NBNEAFNA_01220	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
NBNEAFNA_01221	1.79e-244	-	-	-	S	-	-	-	Helix-turn-helix domain
NBNEAFNA_01222	1.08e-132	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NBNEAFNA_01223	1.37e-162	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NBNEAFNA_01224	2.72e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NBNEAFNA_01225	3.37e-178	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NBNEAFNA_01226	3.67e-86	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NBNEAFNA_01227	4.06e-212	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
NBNEAFNA_01228	7.61e-215	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
NBNEAFNA_01229	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
NBNEAFNA_01230	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
NBNEAFNA_01231	7.94e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
NBNEAFNA_01232	3.71e-300	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
NBNEAFNA_01233	2.07e-198	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NBNEAFNA_01234	1.44e-165	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
NBNEAFNA_01235	1.19e-278	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NBNEAFNA_01236	1.47e-265	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NBNEAFNA_01237	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NBNEAFNA_01238	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
NBNEAFNA_01239	2.5e-233	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
NBNEAFNA_01240	4.15e-187	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
NBNEAFNA_01241	2.66e-219	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NBNEAFNA_01242	1.66e-77	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
NBNEAFNA_01243	3.66e-108	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NBNEAFNA_01244	5.03e-232	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
NBNEAFNA_01245	6.25e-220	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NBNEAFNA_01246	1.49e-110	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
NBNEAFNA_01247	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
NBNEAFNA_01248	3.59e-304	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NBNEAFNA_01249	3.57e-236	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NBNEAFNA_01250	4.97e-311	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
NBNEAFNA_01251	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NBNEAFNA_01252	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
NBNEAFNA_01253	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NBNEAFNA_01254	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NBNEAFNA_01255	5.14e-169	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
NBNEAFNA_01256	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NBNEAFNA_01257	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NBNEAFNA_01258	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
NBNEAFNA_01259	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NBNEAFNA_01260	1.71e-264	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NBNEAFNA_01261	1.48e-26	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
NBNEAFNA_01262	0.0	-	-	-	L	-	-	-	PLD-like domain
NBNEAFNA_01264	7.42e-228	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
NBNEAFNA_01265	6e-228	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NBNEAFNA_01266	3.11e-120	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
NBNEAFNA_01267	3.44e-282	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NBNEAFNA_01268	5.28e-100	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NBNEAFNA_01269	3.66e-146	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
NBNEAFNA_01270	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
NBNEAFNA_01271	2.69e-259	-	-	-	G	-	-	-	Transporter, major facilitator family protein
NBNEAFNA_01272	1.18e-140	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
NBNEAFNA_01273	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
NBNEAFNA_01274	5.88e-233	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
NBNEAFNA_01275	1.73e-215	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
NBNEAFNA_01276	1.62e-227	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NBNEAFNA_01277	5.11e-160	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
NBNEAFNA_01278	3.69e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
NBNEAFNA_01279	7.33e-163	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
NBNEAFNA_01280	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
NBNEAFNA_01281	3.12e-191	-	-	-	O	-	-	-	Band 7 protein
NBNEAFNA_01282	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
NBNEAFNA_01283	7.22e-198	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
NBNEAFNA_01284	1.43e-51	-	-	-	S	-	-	-	Cytochrome B5
NBNEAFNA_01285	1.84e-103	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
NBNEAFNA_01286	2.35e-223	-	-	-	-	-	-	-	-
NBNEAFNA_01287	6.42e-52	-	-	-	-	-	-	-	-
NBNEAFNA_01288	1.21e-265	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NBNEAFNA_01289	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
NBNEAFNA_01290	1.39e-143	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
NBNEAFNA_01291	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
NBNEAFNA_01292	1.3e-114	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
NBNEAFNA_01293	1.43e-40	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
NBNEAFNA_01294	1.67e-251	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
NBNEAFNA_01295	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
NBNEAFNA_01296	4.37e-194	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
NBNEAFNA_01297	1.14e-154	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Putative cyclase
NBNEAFNA_01298	8.25e-47	-	-	-	-	-	-	-	-
NBNEAFNA_01299	5.55e-121	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
NBNEAFNA_01300	1.57e-186	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
NBNEAFNA_01301	1.38e-227	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
NBNEAFNA_01302	3.46e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NBNEAFNA_01303	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
NBNEAFNA_01304	1.62e-230	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NBNEAFNA_01305	4.2e-103	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
NBNEAFNA_01306	2.49e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NBNEAFNA_01307	8.05e-106	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
NBNEAFNA_01308	6.65e-104	usp5	-	-	T	-	-	-	universal stress protein
NBNEAFNA_01309	5.5e-162	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
NBNEAFNA_01310	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
NBNEAFNA_01311	3.69e-54	-	-	-	-	-	-	-	-
NBNEAFNA_01312	3.67e-226	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
NBNEAFNA_01313	3.65e-291	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NBNEAFNA_01314	9.75e-184	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
NBNEAFNA_01315	1.01e-109	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
NBNEAFNA_01316	2.06e-102	-	-	-	Q	-	-	-	Methyltransferase
NBNEAFNA_01317	4.64e-151	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
NBNEAFNA_01318	7.89e-304	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
NBNEAFNA_01319	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
NBNEAFNA_01320	4.28e-176	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
NBNEAFNA_01321	5.36e-270	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
NBNEAFNA_01322	1.83e-296	-	-	-	M	-	-	-	Glycosyl transferase
NBNEAFNA_01323	1.94e-84	-	-	-	-	-	-	-	-
NBNEAFNA_01325	0.0	-	-	-	LV	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
NBNEAFNA_01326	1.32e-05	-	-	-	O	-	-	-	OsmC-like protein
NBNEAFNA_01328	1.49e-105	-	-	-	L	-	-	-	Integrase
NBNEAFNA_01329	4.56e-168	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NBNEAFNA_01330	3.02e-81	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
NBNEAFNA_01331	1.83e-46	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
NBNEAFNA_01332	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
NBNEAFNA_01333	1.29e-108	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
NBNEAFNA_01334	4.46e-46	-	-	-	-	-	-	-	-
NBNEAFNA_01335	0.0	-	-	-	G	-	-	-	Peptidase_C39 like family
NBNEAFNA_01336	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
NBNEAFNA_01337	1.63e-152	-	-	-	M	-	-	-	Bacterial sugar transferase
NBNEAFNA_01338	2.79e-225	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
NBNEAFNA_01339	4.02e-191	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
NBNEAFNA_01340	2.02e-177	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
NBNEAFNA_01341	6.21e-43	-	-	-	-	-	-	-	-
NBNEAFNA_01342	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
NBNEAFNA_01343	2.05e-200	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
NBNEAFNA_01344	0.0	potE	-	-	E	-	-	-	Amino Acid
NBNEAFNA_01345	9.85e-154	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NBNEAFNA_01346	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
NBNEAFNA_01347	4.56e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NBNEAFNA_01348	9.77e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
NBNEAFNA_01349	2.26e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
NBNEAFNA_01350	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NBNEAFNA_01351	1.46e-199	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NBNEAFNA_01352	1.9e-125	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NBNEAFNA_01353	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NBNEAFNA_01354	9.89e-301	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
NBNEAFNA_01355	7.06e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
NBNEAFNA_01356	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NBNEAFNA_01357	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
NBNEAFNA_01358	5.46e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NBNEAFNA_01360	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NBNEAFNA_01361	5.06e-78	-	-	-	-	-	-	-	-
NBNEAFNA_01362	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NBNEAFNA_01363	2.85e-243	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
NBNEAFNA_01364	4.18e-110	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
NBNEAFNA_01365	3.38e-218	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NBNEAFNA_01366	7.93e-151	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NBNEAFNA_01367	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NBNEAFNA_01368	9.36e-48	-	-	-	-	-	-	-	-
NBNEAFNA_01369	1.31e-64	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
NBNEAFNA_01379	1.33e-136	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NBNEAFNA_01381	8.29e-142	-	-	-	S	-	-	-	Domain of unknown function (DUF4393)
NBNEAFNA_01383	8.91e-40	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
NBNEAFNA_01384	2.17e-97	-	-	-	K	-	-	-	Peptidase S24-like
NBNEAFNA_01385	5.35e-06	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NBNEAFNA_01386	2.3e-115	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
NBNEAFNA_01398	2.71e-66	-	-	-	S	-	-	-	ERF superfamily
NBNEAFNA_01399	4.5e-15	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
NBNEAFNA_01400	2.36e-88	-	-	-	L	-	-	-	DnaD domain protein
NBNEAFNA_01401	7.28e-45	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
NBNEAFNA_01404	5.68e-29	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
NBNEAFNA_01405	1.97e-07	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NBNEAFNA_01407	2.29e-16	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NBNEAFNA_01411	6.93e-60	-	-	-	S	-	-	-	Domain of unknown function (DUF4868)
NBNEAFNA_01412	2.96e-107	-	-	-	-	-	-	-	-
NBNEAFNA_01414	1.56e-78	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
NBNEAFNA_01415	8.29e-77	-	-	-	L	-	-	-	HNH nucleases
NBNEAFNA_01416	2.37e-82	-	-	-	L	-	-	-	Phage terminase, small subunit
NBNEAFNA_01417	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
NBNEAFNA_01419	1.22e-272	-	-	-	S	-	-	-	Phage portal protein
NBNEAFNA_01420	2.07e-153	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
NBNEAFNA_01421	1.73e-240	-	-	-	S	-	-	-	Phage capsid family
NBNEAFNA_01422	5.79e-54	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
NBNEAFNA_01424	1.32e-40	-	-	-	S	-	-	-	exonuclease activity
NBNEAFNA_01426	1.21e-101	-	-	-	S	-	-	-	Phage tail tube protein
NBNEAFNA_01429	2.05e-156	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
NBNEAFNA_01430	9.75e-105	-	-	-	S	-	-	-	Phage tail protein
NBNEAFNA_01431	6.97e-172	-	-	-	M	-	-	-	Prophage endopeptidase tail
NBNEAFNA_01432	1.5e-48	-	-	-	LM	-	-	-	gp58-like protein
NBNEAFNA_01439	5.75e-44	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
NBNEAFNA_01440	5.88e-185	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
NBNEAFNA_01441	2.39e-13	-	-	-	T	-	-	-	SpoVT / AbrB like domain
NBNEAFNA_01442	3.62e-31	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
NBNEAFNA_01443	8.02e-34	-	-	-	K	-	-	-	TRANSCRIPTIONal
NBNEAFNA_01444	2.01e-07	-	-	-	K	-	-	-	TRANSCRIPTIONal
NBNEAFNA_01445	3.08e-81	yju3	-	-	I	-	-	-	Serine aminopeptidase, S33
NBNEAFNA_01446	1.56e-102	pncA	-	-	Q	-	-	-	Isochorismatase family
NBNEAFNA_01447	1.26e-263	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NBNEAFNA_01448	1.38e-106	-	-	-	F	-	-	-	NUDIX domain
NBNEAFNA_01449	7.11e-71	-	-	-	S	-	-	-	Phage portal protein
NBNEAFNA_01450	2.03e-133	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
NBNEAFNA_01451	4.48e-34	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
NBNEAFNA_01452	3.09e-104	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
NBNEAFNA_01453	4.88e-59	-	-	-	DJ	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
NBNEAFNA_01454	7.37e-37	-	-	-	-	-	-	-	-
NBNEAFNA_01455	6.62e-242	-	-	-	S	-	-	-	overlaps another CDS with the same product name
NBNEAFNA_01456	1.03e-215	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
NBNEAFNA_01457	1.62e-74	-	-	-	H	-	-	-	Riboflavin biosynthesis protein RibD
NBNEAFNA_01458	7.3e-118	-	-	-	S	-	-	-	PFAM Archaeal ATPase
NBNEAFNA_01459	5.26e-203	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
NBNEAFNA_01460	1.18e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NBNEAFNA_01461	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
NBNEAFNA_01462	9.11e-106	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
NBNEAFNA_01463	1.68e-294	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NBNEAFNA_01464	1.03e-299	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
NBNEAFNA_01465	5.43e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
NBNEAFNA_01466	4.89e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
NBNEAFNA_01467	1.62e-210	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
NBNEAFNA_01468	9.85e-131	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
NBNEAFNA_01469	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NBNEAFNA_01470	1.64e-199	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NBNEAFNA_01471	7.85e-84	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
NBNEAFNA_01472	7.18e-153	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NBNEAFNA_01473	3.85e-198	gspA	-	-	M	-	-	-	family 8
NBNEAFNA_01474	3.87e-202	-	-	-	S	-	-	-	Alpha beta hydrolase
NBNEAFNA_01475	3.05e-121	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NBNEAFNA_01476	5.05e-103	-	-	-	S	-	-	-	Cupin domain
NBNEAFNA_01477	3.8e-58	-	-	-	S	-	-	-	UPF0756 membrane protein
NBNEAFNA_01478	2.27e-306	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NBNEAFNA_01479	1.55e-94	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
NBNEAFNA_01480	1.19e-315	yhdP	-	-	S	-	-	-	Transporter associated domain
NBNEAFNA_01481	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
NBNEAFNA_01482	7.09e-184	-	-	-	S	-	-	-	DUF218 domain
NBNEAFNA_01483	2.79e-89	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NBNEAFNA_01484	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NBNEAFNA_01485	1.42e-214	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
NBNEAFNA_01486	1.9e-139	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NBNEAFNA_01487	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NBNEAFNA_01488	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NBNEAFNA_01489	3.29e-109	-	-	-	F	-	-	-	NUDIX domain
NBNEAFNA_01490	1.81e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
NBNEAFNA_01491	1.5e-88	-	-	-	S	-	-	-	Belongs to the HesB IscA family
NBNEAFNA_01492	1.04e-103	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
NBNEAFNA_01493	8.21e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NBNEAFNA_01494	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
NBNEAFNA_01495	6.32e-99	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
NBNEAFNA_01496	1.5e-195	yeaE	-	-	S	-	-	-	Aldo keto
NBNEAFNA_01497	1.8e-306	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
NBNEAFNA_01498	8.64e-253	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NBNEAFNA_01499	4.89e-191	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
NBNEAFNA_01500	5.1e-134	-	-	-	M	-	-	-	LysM domain protein
NBNEAFNA_01501	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
NBNEAFNA_01502	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
NBNEAFNA_01503	5.13e-61	-	-	-	-	-	-	-	-
NBNEAFNA_01504	2.56e-307	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
NBNEAFNA_01505	1.95e-109	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
NBNEAFNA_01506	3.56e-29	-	-	-	-	-	-	-	-
NBNEAFNA_01507	2.34e-97	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
NBNEAFNA_01508	3.42e-179	-	-	-	S	-	-	-	Membrane
NBNEAFNA_01509	8.05e-179	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
NBNEAFNA_01510	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
NBNEAFNA_01511	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NBNEAFNA_01512	7.86e-301	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
NBNEAFNA_01513	4.85e-187	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
NBNEAFNA_01514	6.48e-308	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
NBNEAFNA_01515	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
NBNEAFNA_01516	1.3e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
NBNEAFNA_01517	8.52e-267	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NBNEAFNA_01518	7.38e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NBNEAFNA_01519	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
NBNEAFNA_01520	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NBNEAFNA_01521	9.07e-300	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
NBNEAFNA_01522	4.1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NBNEAFNA_01523	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NBNEAFNA_01524	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NBNEAFNA_01525	3.01e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NBNEAFNA_01526	5.79e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NBNEAFNA_01527	7.57e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NBNEAFNA_01528	5.46e-186	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NBNEAFNA_01529	2.36e-56	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
NBNEAFNA_01530	3.89e-215	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NBNEAFNA_01531	3.88e-92	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
NBNEAFNA_01532	3.25e-292	-	-	-	V	-	-	-	MatE
NBNEAFNA_01533	0.0	potE	-	-	E	-	-	-	Amino Acid
NBNEAFNA_01534	3.7e-36	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NBNEAFNA_01535	7.04e-222	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NBNEAFNA_01536	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NBNEAFNA_01537	1.49e-154	-	-	-	S	-	-	-	repeat protein
NBNEAFNA_01538	5.48e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
NBNEAFNA_01539	3.57e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NBNEAFNA_01540	5.58e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
NBNEAFNA_01541	1.01e-274	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NBNEAFNA_01542	2.3e-160	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NBNEAFNA_01543	4.49e-26	-	-	-	-	-	-	-	-
NBNEAFNA_01544	2.48e-129	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
NBNEAFNA_01545	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
NBNEAFNA_01546	6.26e-24	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
NBNEAFNA_01547	6.91e-137	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
NBNEAFNA_01548	4.3e-142	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
NBNEAFNA_01549	6.28e-116	-	-	-	-	-	-	-	-
NBNEAFNA_01550	4.61e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
NBNEAFNA_01551	3.7e-32	yttB	-	-	EGP	-	-	-	Major Facilitator
NBNEAFNA_01552	5.36e-61	yttB	-	-	EGP	-	-	-	Major Facilitator
NBNEAFNA_01553	2.65e-137	yttB	-	-	EGP	-	-	-	Major Facilitator
NBNEAFNA_01554	9.1e-141	-	-	-	-	-	-	-	-
NBNEAFNA_01555	1.51e-32	-	-	-	-	-	-	-	-
NBNEAFNA_01556	2.55e-219	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
NBNEAFNA_01557	5.3e-291	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NBNEAFNA_01560	2.75e-136	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
NBNEAFNA_01561	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NBNEAFNA_01562	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NBNEAFNA_01563	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
NBNEAFNA_01564	2.87e-219	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
NBNEAFNA_01565	1.59e-266	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
NBNEAFNA_01566	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
NBNEAFNA_01567	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
NBNEAFNA_01568	1.24e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
NBNEAFNA_01569	2.35e-92	-	-	-	-	-	-	-	-
NBNEAFNA_01570	1.24e-112	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
NBNEAFNA_01571	4.12e-149	dltr	-	-	K	-	-	-	response regulator
NBNEAFNA_01572	1.32e-267	sptS	-	-	T	-	-	-	Histidine kinase
NBNEAFNA_01573	5.36e-270	-	-	-	P	-	-	-	Voltage gated chloride channel
NBNEAFNA_01574	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
NBNEAFNA_01575	6.13e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
NBNEAFNA_01576	1.21e-213	-	-	-	C	-	-	-	Aldo keto reductase
NBNEAFNA_01577	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
NBNEAFNA_01578	3.77e-113	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
NBNEAFNA_01579	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
NBNEAFNA_01580	4.02e-237	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NBNEAFNA_01581	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NBNEAFNA_01582	8.17e-120	-	-	-	-	-	-	-	-
NBNEAFNA_01583	1.5e-121	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NBNEAFNA_01585	1.45e-145	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
NBNEAFNA_01586	8.53e-95	-	-	-	-	-	-	-	-
NBNEAFNA_01587	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NBNEAFNA_01588	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
NBNEAFNA_01589	0.0	-	-	-	M	-	-	-	domain protein
NBNEAFNA_01590	7.89e-123	-	-	-	L	-	-	-	Transposase
NBNEAFNA_01591	3.63e-166	-	-	-	L	-	-	-	Transposase
NBNEAFNA_01592	8.57e-87	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
NBNEAFNA_01593	3.7e-19	-	-	-	-	-	-	-	-
NBNEAFNA_01594	5.71e-263	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
NBNEAFNA_01595	3.16e-121	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
NBNEAFNA_01596	4.89e-122	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
NBNEAFNA_01597	2.32e-104	-	-	-	-	-	-	-	-
NBNEAFNA_01598	5.52e-168	-	-	-	M	-	-	-	Lysin motif
NBNEAFNA_01599	7.33e-253	-	-	-	EGP	-	-	-	Major Facilitator
NBNEAFNA_01600	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NBNEAFNA_01601	9.71e-253	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
NBNEAFNA_01603	3.37e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NBNEAFNA_01605	3.36e-77	-	-	-	-	-	-	-	-
NBNEAFNA_01606	1.62e-229	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
NBNEAFNA_01607	1.08e-161	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NBNEAFNA_01608	3.95e-71	-	-	-	-	-	-	-	-
NBNEAFNA_01609	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NBNEAFNA_01610	8.59e-98	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NBNEAFNA_01611	5.43e-29	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
NBNEAFNA_01612	2.32e-85	-	-	-	S	-	-	-	Putative HNHc nuclease
NBNEAFNA_01613	7.6e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF1071)
NBNEAFNA_01621	2.52e-95	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
NBNEAFNA_01623	1.21e-21	-	-	-	K	-	-	-	sequence-specific DNA binding
NBNEAFNA_01625	5.06e-31	-	-	-	S	-	-	-	Short C-terminal domain
NBNEAFNA_01628	4.92e-167	-	-	-	S	-	-	-	Recombinase
NBNEAFNA_01629	1.92e-240	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBNEAFNA_01630	1.7e-173	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NBNEAFNA_01631	1.51e-202	-	-	-	-	-	-	-	-
NBNEAFNA_01632	1.63e-198	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
NBNEAFNA_01633	1.17e-234	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
NBNEAFNA_01634	1.44e-168	XK27_07210	-	-	S	-	-	-	B3 4 domain
NBNEAFNA_01635	8.16e-103	yybA	-	-	K	-	-	-	Transcriptional regulator
NBNEAFNA_01636	1.06e-117	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
NBNEAFNA_01637	5.68e-117	-	-	-	GM	-	-	-	epimerase
NBNEAFNA_01638	1.02e-200	-	-	-	V	-	-	-	(ABC) transporter
NBNEAFNA_01639	8.65e-310	yhdP	-	-	S	-	-	-	Transporter associated domain
NBNEAFNA_01640	4.88e-261	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
NBNEAFNA_01641	3.85e-197	yvgN	-	-	S	-	-	-	Aldo keto reductase
NBNEAFNA_01642	4.09e-131	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
NBNEAFNA_01643	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
NBNEAFNA_01644	2.71e-178	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NBNEAFNA_01645	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
NBNEAFNA_01646	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NBNEAFNA_01647	3.82e-193	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NBNEAFNA_01648	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
NBNEAFNA_01649	1.82e-172	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
NBNEAFNA_01650	4.73e-113	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NBNEAFNA_01651	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NBNEAFNA_01652	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NBNEAFNA_01653	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NBNEAFNA_01654	1.87e-177	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NBNEAFNA_01655	5.53e-130	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NBNEAFNA_01656	7.84e-119	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
NBNEAFNA_01657	1.72e-98	ykuL	-	-	S	-	-	-	(CBS) domain
NBNEAFNA_01658	2.71e-196	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NBNEAFNA_01659	5.96e-186	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
NBNEAFNA_01660	3.61e-70	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NBNEAFNA_01661	3.04e-74	-	-	-	-	-	-	-	-
NBNEAFNA_01662	4.72e-264	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NBNEAFNA_01663	2.21e-231	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
NBNEAFNA_01664	4.1e-172	-	-	-	-	-	-	-	-
NBNEAFNA_01665	6.77e-166	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
NBNEAFNA_01666	1.66e-35	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NBNEAFNA_01668	0.0	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NBNEAFNA_01669	3.88e-206	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NBNEAFNA_01670	1.37e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NBNEAFNA_01671	7.77e-262	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NBNEAFNA_01672	2.51e-197	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NBNEAFNA_01673	6.63e-203	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
NBNEAFNA_01674	1.42e-222	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NBNEAFNA_01675	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
NBNEAFNA_01676	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
NBNEAFNA_01677	1.57e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NBNEAFNA_01678	3.01e-107	-	-	-	-	-	-	-	-
NBNEAFNA_01679	1.78e-204	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
NBNEAFNA_01680	1.47e-216	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NBNEAFNA_01681	2.41e-280	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
NBNEAFNA_01682	1.57e-56	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
NBNEAFNA_01683	3.3e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NBNEAFNA_01684	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
NBNEAFNA_01685	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NBNEAFNA_01687	2.13e-258	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NBNEAFNA_01688	0.0	-	-	-	L	-	-	-	DNA helicase
NBNEAFNA_01689	7.04e-107	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
NBNEAFNA_01690	6.41e-236	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
NBNEAFNA_01691	3.2e-242	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NBNEAFNA_01692	2.53e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NBNEAFNA_01693	2.47e-291	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
NBNEAFNA_01694	3.51e-224	-	-	-	-	-	-	-	-
NBNEAFNA_01695	4.85e-167	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
NBNEAFNA_01697	2.25e-206	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
NBNEAFNA_01698	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NBNEAFNA_01699	2.42e-196	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
NBNEAFNA_01700	6.03e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NBNEAFNA_01701	5.93e-205	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NBNEAFNA_01702	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
NBNEAFNA_01703	1.41e-205	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NBNEAFNA_01704	1.3e-211	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NBNEAFNA_01705	4.85e-158	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NBNEAFNA_01706	2.49e-165	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
NBNEAFNA_01707	2.09e-190	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
NBNEAFNA_01708	1.37e-315	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NBNEAFNA_01709	3.53e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NBNEAFNA_01710	7.94e-101	-	-	-	-	-	-	-	-
NBNEAFNA_01711	3.26e-64	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
NBNEAFNA_01712	1.07e-150	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
NBNEAFNA_01713	2.58e-187	yidA	-	-	S	-	-	-	hydrolase
NBNEAFNA_01714	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
NBNEAFNA_01715	3.16e-193	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
NBNEAFNA_01716	6.53e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
NBNEAFNA_01717	6.44e-68	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NBNEAFNA_01718	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NBNEAFNA_01719	3.89e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NBNEAFNA_01720	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
NBNEAFNA_01721	9.83e-298	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NBNEAFNA_01722	1.47e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NBNEAFNA_01723	3.92e-38	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
NBNEAFNA_01724	9.47e-95	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
NBNEAFNA_01725	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
NBNEAFNA_01726	3.25e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
NBNEAFNA_01727	5.58e-192	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NBNEAFNA_01728	2.6e-156	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
NBNEAFNA_01730	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NBNEAFNA_01731	1.12e-211	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
NBNEAFNA_01732	4.44e-292	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
NBNEAFNA_01733	9.43e-166	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NBNEAFNA_01734	2.09e-150	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NBNEAFNA_01735	1.07e-103	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
NBNEAFNA_01736	5.55e-248	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
NBNEAFNA_01737	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
NBNEAFNA_01738	2.07e-210	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NBNEAFNA_01739	5.31e-138	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
NBNEAFNA_01740	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
NBNEAFNA_01741	5.34e-245	mocA	-	-	S	-	-	-	Oxidoreductase
NBNEAFNA_01742	4.3e-294	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
NBNEAFNA_01744	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NBNEAFNA_01745	5.83e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NBNEAFNA_01746	2.28e-270	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NBNEAFNA_01747	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NBNEAFNA_01748	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NBNEAFNA_01749	3.53e-168	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
NBNEAFNA_01750	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
NBNEAFNA_01751	4.55e-315	-	-	-	EGP	-	-	-	Major Facilitator
NBNEAFNA_01752	7.7e-144	-	-	-	-	-	-	-	-
NBNEAFNA_01755	4.13e-190	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NBNEAFNA_01756	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
NBNEAFNA_01758	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
NBNEAFNA_01759	5.31e-143	nanA	4.1.3.3	-	E	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NBNEAFNA_01760	1.15e-144	repA	-	-	S	-	-	-	Replication initiator protein A
NBNEAFNA_01761	1.05e-95	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
NBNEAFNA_01762	1.09e-196	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
NBNEAFNA_01763	2.58e-113	-	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
NBNEAFNA_01764	6.43e-251	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NBNEAFNA_01766	1.35e-261	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
NBNEAFNA_01767	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
NBNEAFNA_01768	2.45e-310	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
NBNEAFNA_01769	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NBNEAFNA_01770	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
NBNEAFNA_01772	1.29e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
NBNEAFNA_01773	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NBNEAFNA_01774	8.68e-316	yycH	-	-	S	-	-	-	YycH protein
NBNEAFNA_01775	2.91e-192	yycI	-	-	S	-	-	-	YycH protein
NBNEAFNA_01776	8.43e-195	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
NBNEAFNA_01777	7.71e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NBNEAFNA_01778	7.41e-108	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NBNEAFNA_01779	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
NBNEAFNA_01780	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NBNEAFNA_01781	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NBNEAFNA_01782	2.42e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NBNEAFNA_01783	1.28e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
NBNEAFNA_01784	8.32e-226	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
NBNEAFNA_01785	1.98e-278	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
NBNEAFNA_01787	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
NBNEAFNA_01788	8.97e-161	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
NBNEAFNA_01789	2.21e-121	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
NBNEAFNA_01790	4.52e-12	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
NBNEAFNA_01791	5.15e-48	hxlR	-	-	K	-	-	-	regulation of RNA biosynthetic process
NBNEAFNA_01792	4.54e-208	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
NBNEAFNA_01793	0.0	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
NBNEAFNA_01794	1.3e-263	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
NBNEAFNA_01795	2.3e-131	pncA	-	-	Q	-	-	-	Isochorismatase family
NBNEAFNA_01796	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NBNEAFNA_01797	1.97e-169	-	-	-	F	-	-	-	NUDIX domain
NBNEAFNA_01798	3.51e-125	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
NBNEAFNA_01799	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NBNEAFNA_01800	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NBNEAFNA_01801	7.15e-122	cvpA	-	-	S	-	-	-	Colicin V production protein
NBNEAFNA_01802	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
NBNEAFNA_01803	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NBNEAFNA_01804	1.34e-56	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
NBNEAFNA_01805	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NBNEAFNA_01806	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NBNEAFNA_01807	6.15e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
NBNEAFNA_01808	3.56e-60	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
NBNEAFNA_01809	8.04e-238	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NBNEAFNA_01810	1.16e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NBNEAFNA_01811	8.76e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NBNEAFNA_01812	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NBNEAFNA_01813	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NBNEAFNA_01814	1.46e-272	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
NBNEAFNA_01815	2.2e-251	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NBNEAFNA_01816	6.25e-287	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
NBNEAFNA_01817	1.36e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NBNEAFNA_01818	5.32e-200	-	-	-	S	-	-	-	Helix-turn-helix domain
NBNEAFNA_01819	1.25e-315	ymfH	-	-	S	-	-	-	Peptidase M16
NBNEAFNA_01820	8.29e-292	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
NBNEAFNA_01821	1.92e-203	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
NBNEAFNA_01822	2.06e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NBNEAFNA_01823	8.97e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NBNEAFNA_01824	1.69e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
NBNEAFNA_01825	2.12e-192	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
NBNEAFNA_01826	3.39e-229	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
NBNEAFNA_01827	6.98e-156	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
NBNEAFNA_01828	1.26e-304	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NBNEAFNA_01829	1.01e-291	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
NBNEAFNA_01830	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NBNEAFNA_01831	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NBNEAFNA_01832	4.67e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
NBNEAFNA_01833	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
NBNEAFNA_01834	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
NBNEAFNA_01835	9.01e-231	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
NBNEAFNA_01836	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NBNEAFNA_01837	2.1e-129	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
NBNEAFNA_01838	2.92e-265	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
NBNEAFNA_01839	3.27e-224	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NBNEAFNA_01840	0.0	-	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
NBNEAFNA_01841	6.17e-44	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Competence-damaged protein
NBNEAFNA_01842	1.15e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase
NBNEAFNA_01843	1.06e-186	-	-	-	L	-	-	-	4.5 Transposon and IS
NBNEAFNA_01844	1.02e-72	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
NBNEAFNA_01845	1.02e-137	-	-	-	I	-	-	-	Carboxylesterase family
NBNEAFNA_01846	6.56e-118	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
NBNEAFNA_01847	6.46e-288	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NBNEAFNA_01848	3.28e-177	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NBNEAFNA_01849	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NBNEAFNA_01850	3.82e-316	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NBNEAFNA_01851	3.87e-151	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
NBNEAFNA_01852	6.23e-115	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NBNEAFNA_01857	9.69e-50	-	-	-	K	-	-	-	Helix-turn-helix domain
NBNEAFNA_01858	2.36e-84	-	-	-	S	-	-	-	DNA binding
NBNEAFNA_01862	1.76e-153	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
NBNEAFNA_01863	2.17e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
NBNEAFNA_01864	9.66e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NBNEAFNA_01866	1.32e-65	-	-	-	G	-	-	-	Right handed beta helix region
NBNEAFNA_01867	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NBNEAFNA_01868	8.01e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
NBNEAFNA_01869	1.84e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NBNEAFNA_01870	7.58e-134	-	-	-	-	-	-	-	-
NBNEAFNA_01871	1.56e-108	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NBNEAFNA_01872	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NBNEAFNA_01873	4.68e-187	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
NBNEAFNA_01874	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
NBNEAFNA_01875	4.67e-11	-	-	-	-	-	-	-	-
NBNEAFNA_01876	9.37e-294	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NBNEAFNA_01877	3.31e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
NBNEAFNA_01878	1.34e-147	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
NBNEAFNA_01879	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NBNEAFNA_01880	4.18e-15	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NBNEAFNA_01881	1.25e-55	-	-	-	-	-	-	-	-
NBNEAFNA_01882	1.1e-199	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
NBNEAFNA_01884	2.18e-70	-	-	-	L	-	-	-	Resolvase, N terminal domain
NBNEAFNA_01885	2.83e-180	kdsA	2.5.1.55	-	H	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the KdsA family
NBNEAFNA_01886	1.22e-180	kdsD	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	sugar phosphate isomerase involved in capsule formation
NBNEAFNA_01887	4.47e-10	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
NBNEAFNA_01888	2.87e-218	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NBNEAFNA_01889	6.82e-310	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NBNEAFNA_01890	4.31e-104	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NBNEAFNA_01891	3.03e-71	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NBNEAFNA_01892	3.02e-162	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NBNEAFNA_01893	1.51e-147	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NBNEAFNA_01894	9.09e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
NBNEAFNA_01895	2.15e-121	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NBNEAFNA_01896	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
NBNEAFNA_01898	1.42e-116	-	-	-	L	-	-	-	Initiator Replication protein
NBNEAFNA_01899	3.93e-25	-	-	-	-	-	-	-	-
NBNEAFNA_01900	9.22e-58	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
NBNEAFNA_01901	1.24e-68	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
NBNEAFNA_01902	7.41e-46	-	-	-	-	-	-	-	-
NBNEAFNA_01903	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NBNEAFNA_01904	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
NBNEAFNA_01905	4.49e-182	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NBNEAFNA_01906	5.33e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NBNEAFNA_01907	3.74e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
NBNEAFNA_01908	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
NBNEAFNA_01909	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NBNEAFNA_01910	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NBNEAFNA_01911	4.6e-259	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NBNEAFNA_01912	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
NBNEAFNA_01913	1.83e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NBNEAFNA_01914	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NBNEAFNA_01915	2.24e-239	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NBNEAFNA_01916	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NBNEAFNA_01917	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
NBNEAFNA_01918	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
NBNEAFNA_01919	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
NBNEAFNA_01920	4.7e-157	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
NBNEAFNA_01921	4.49e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
NBNEAFNA_01922	1.15e-206	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NBNEAFNA_01923	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
NBNEAFNA_01924	1.74e-167	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
NBNEAFNA_01925	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NBNEAFNA_01926	2.37e-221	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NBNEAFNA_01927	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NBNEAFNA_01928	1.22e-270	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NBNEAFNA_01929	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NBNEAFNA_01930	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NBNEAFNA_01931	1.23e-69	-	-	-	-	-	-	-	-
NBNEAFNA_01932	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
NBNEAFNA_01933	1.11e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NBNEAFNA_01934	1.97e-191	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
NBNEAFNA_01935	1.64e-203	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NBNEAFNA_01936	9.49e-57	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NBNEAFNA_01937	6.32e-309	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NBNEAFNA_01938	5.62e-193	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NBNEAFNA_01939	2.24e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NBNEAFNA_01940	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
NBNEAFNA_01941	2.44e-116	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
NBNEAFNA_01942	1.15e-14	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
NBNEAFNA_01943	5.86e-254	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NBNEAFNA_01944	7.44e-168	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NBNEAFNA_01945	5.07e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
NBNEAFNA_01946	1.2e-70	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
NBNEAFNA_01947	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
NBNEAFNA_01948	1.76e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
NBNEAFNA_01949	8.24e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NBNEAFNA_01950	1.05e-226	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
NBNEAFNA_01951	1.09e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
NBNEAFNA_01952	7.79e-281	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
NBNEAFNA_01953	4.95e-63	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
NBNEAFNA_01954	1.28e-274	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NBNEAFNA_01955	1e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
NBNEAFNA_01956	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NBNEAFNA_01957	1e-166	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NBNEAFNA_01958	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NBNEAFNA_01959	8.25e-218	-	-	-	G	-	-	-	Phosphotransferase enzyme family
NBNEAFNA_01960	8.01e-97	-	-	-	O	-	-	-	OsmC-like protein
NBNEAFNA_01961	8.91e-224	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBNEAFNA_01962	1.23e-276	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NBNEAFNA_01963	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
NBNEAFNA_01964	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NBNEAFNA_01965	1.92e-204	-	-	-	EG	-	-	-	EamA-like transporter family
NBNEAFNA_01966	3.06e-216	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
NBNEAFNA_01967	3.75e-32	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
NBNEAFNA_01968	3.08e-180	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
NBNEAFNA_01969	4.21e-48	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
NBNEAFNA_01970	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
NBNEAFNA_01971	1.62e-279	arcT	-	-	E	-	-	-	Aminotransferase
NBNEAFNA_01972	8.23e-215	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
NBNEAFNA_01973	1.92e-102	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
NBNEAFNA_01974	1.73e-97	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
NBNEAFNA_01975	7.48e-260	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NBNEAFNA_01977	1.08e-266	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
NBNEAFNA_01978	4.51e-54	-	-	-	S	-	-	-	Cytochrome B5
NBNEAFNA_01979	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
NBNEAFNA_01980	9.37e-52	-	-	-	S	-	-	-	Cytochrome B5
NBNEAFNA_01981	5.81e-96	-	-	-	S	ko:K02348	-	ko00000	Gnat family
NBNEAFNA_01982	1.84e-155	-	-	-	GM	-	-	-	NmrA-like family
NBNEAFNA_01983	1.85e-67	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NBNEAFNA_01984	3.2e-138	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
NBNEAFNA_01985	1.54e-99	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NBNEAFNA_01986	1.84e-56	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
NBNEAFNA_01987	2.36e-113	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NBNEAFNA_01989	5.8e-105	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
NBNEAFNA_01990	3.41e-159	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
NBNEAFNA_01991	4.31e-123	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
NBNEAFNA_01992	1.2e-111	flp	-	-	V	-	-	-	Beta-lactamase
NBNEAFNA_01993	3.87e-46	flp	-	-	V	-	-	-	Beta-lactamase
NBNEAFNA_01994	4.26e-46	flp	-	-	V	-	-	-	Beta-lactamase
NBNEAFNA_01995	2.23e-71	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
NBNEAFNA_01996	1.22e-113	-	-	-	J	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
NBNEAFNA_01997	5.31e-58	-	-	-	-	-	-	-	-
NBNEAFNA_01999	4.44e-91	-	-	-	-	-	-	-	-
NBNEAFNA_02000	1.43e-73	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NBNEAFNA_02001	1.85e-120	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NBNEAFNA_02002	2.27e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
NBNEAFNA_02003	5.27e-281	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NBNEAFNA_02004	9.17e-131	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
NBNEAFNA_02005	1.53e-266	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
NBNEAFNA_02006	1.88e-60	-	-	-	-	-	-	-	-
NBNEAFNA_02007	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NBNEAFNA_02008	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NBNEAFNA_02009	2.17e-245	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
NBNEAFNA_02010	5.03e-95	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
NBNEAFNA_02011	1.98e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
NBNEAFNA_02012	2.03e-66	-	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NBNEAFNA_02013	6.56e-121	-	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NBNEAFNA_02014	3.89e-242	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
NBNEAFNA_02015	1.72e-150	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
NBNEAFNA_02016	1.25e-208	gpG	-	-	-	-	-	-	-
NBNEAFNA_02017	3.98e-108	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)