ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
LHAPMBCL_00001 1.31e-64 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
LHAPMBCL_00002 9.36e-48 - - - - - - - -
LHAPMBCL_00003 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHAPMBCL_00004 7.93e-151 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHAPMBCL_00005 3.38e-218 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
LHAPMBCL_00006 4.18e-110 - - - K - - - transcriptional regulator (TetR family)
LHAPMBCL_00007 2.85e-243 - - - E - - - Zinc-binding dehydrogenase
LHAPMBCL_00008 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LHAPMBCL_00009 5.06e-78 - - - - - - - -
LHAPMBCL_00010 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LHAPMBCL_00012 0.0 potE - - E - - - Amino Acid
LHAPMBCL_00013 2.05e-200 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
LHAPMBCL_00014 1.26e-46 - - - S - - - Protein of unknown function (DUF2922)
LHAPMBCL_00015 6.21e-43 - - - - - - - -
LHAPMBCL_00016 2.02e-177 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
LHAPMBCL_00017 4.02e-191 cps1D - - M - - - Domain of unknown function (DUF4422)
LHAPMBCL_00018 2.79e-225 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
LHAPMBCL_00019 1.63e-152 - - - M - - - Bacterial sugar transferase
LHAPMBCL_00020 0.0 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
LHAPMBCL_00021 0.0 - - - G - - - Peptidase_C39 like family
LHAPMBCL_00022 4.46e-46 - - - - - - - -
LHAPMBCL_00023 1.29e-108 is18 - - L - - - COG2801 Transposase and inactivated derivatives
LHAPMBCL_00024 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
LHAPMBCL_00025 1.83e-46 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
LHAPMBCL_00026 3.02e-81 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
LHAPMBCL_00027 4.56e-168 - - - S - - - haloacid dehalogenase-like hydrolase
LHAPMBCL_00028 1.49e-105 - - - L - - - Integrase
LHAPMBCL_00030 1.32e-05 - - - O - - - OsmC-like protein
LHAPMBCL_00031 0.0 - - - LV - - - site-specific DNA-methyltransferase (adenine-specific) activity
LHAPMBCL_00033 6.42e-52 - - - - - - - -
LHAPMBCL_00034 1.21e-265 - - - EGP - - - Major Facilitator Superfamily
LHAPMBCL_00035 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
LHAPMBCL_00036 1.39e-143 - - - GM - - - NAD dependent epimerase dehydratase family protein
LHAPMBCL_00037 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
LHAPMBCL_00038 1.3e-114 - - - S - - - ECF transporter, substrate-specific component
LHAPMBCL_00039 1.43e-40 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LHAPMBCL_00040 1.67e-251 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
LHAPMBCL_00041 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
LHAPMBCL_00042 4.37e-194 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
LHAPMBCL_00043 1.14e-154 XK27_00940 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Putative cyclase
LHAPMBCL_00044 3.29e-146 - - - S - - - (CBS) domain
LHAPMBCL_00045 1.13e-131 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LHAPMBCL_00046 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LHAPMBCL_00047 5.83e-52 yabO - - J - - - S4 domain protein
LHAPMBCL_00048 4.31e-76 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
LHAPMBCL_00049 5.75e-103 yabR - - J ko:K07571 - ko00000 RNA binding
LHAPMBCL_00050 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LHAPMBCL_00051 8.67e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
LHAPMBCL_00052 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LHAPMBCL_00053 1.13e-218 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LHAPMBCL_00054 8.82e-241 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LHAPMBCL_00055 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
LHAPMBCL_00056 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LHAPMBCL_00057 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
LHAPMBCL_00058 1.88e-222 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LHAPMBCL_00059 1.18e-30 - - - S - - - Protein of unknown function (DUF3042)
LHAPMBCL_00060 1.55e-87 yqhL - - P - - - Rhodanese-like protein
LHAPMBCL_00061 1.77e-235 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
LHAPMBCL_00062 7.07e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
LHAPMBCL_00063 1.66e-138 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
LHAPMBCL_00064 2.68e-129 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LHAPMBCL_00065 1.53e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LHAPMBCL_00066 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LHAPMBCL_00067 0.0 - - - S - - - membrane
LHAPMBCL_00068 2.13e-88 yneR - - S - - - Belongs to the HesB IscA family
LHAPMBCL_00069 3.52e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LHAPMBCL_00070 2.8e-150 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
LHAPMBCL_00071 2.82e-147 - - - M - - - PFAM NLP P60 protein
LHAPMBCL_00072 1.56e-121 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
LHAPMBCL_00073 6.66e-281 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LHAPMBCL_00074 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
LHAPMBCL_00075 1.77e-56 - - - - - - - -
LHAPMBCL_00076 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
LHAPMBCL_00077 6.85e-194 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LHAPMBCL_00078 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
LHAPMBCL_00079 2.18e-112 - - - T - - - Belongs to the universal stress protein A family
LHAPMBCL_00080 6.15e-224 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LHAPMBCL_00081 5.44e-25 - - - K - - - Transcriptional regulator
LHAPMBCL_00082 3.91e-131 - - - U - - - Belongs to the major facilitator superfamily
LHAPMBCL_00083 3.06e-150 dgk2 - - F - - - deoxynucleoside kinase
LHAPMBCL_00084 4.21e-144 - - - - - - - -
LHAPMBCL_00085 1.63e-234 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
LHAPMBCL_00086 6.94e-209 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LHAPMBCL_00087 1.98e-196 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LHAPMBCL_00088 2.48e-125 - 2.1.1.72, 3.1.21.3 AA10,CBM73 M ko:K01154,ko:K02014,ko:K03933,ko:K07316 - ko00000,ko01000,ko02000,ko02048 domain protein
LHAPMBCL_00089 1.01e-38 - - - S - - - YSIRK type signal peptide
LHAPMBCL_00090 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LHAPMBCL_00091 8.09e-280 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LHAPMBCL_00092 4.47e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHAPMBCL_00093 3.51e-101 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
LHAPMBCL_00095 5.8e-176 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LHAPMBCL_00096 0.0 yhaN - - L - - - AAA domain
LHAPMBCL_00097 1.92e-284 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
LHAPMBCL_00098 2.42e-64 yheA - - S - - - Belongs to the UPF0342 family
LHAPMBCL_00099 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LHAPMBCL_00100 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
LHAPMBCL_00101 2.41e-158 - - - F - - - glutamine amidotransferase
LHAPMBCL_00102 9.68e-83 - - - - - - - -
LHAPMBCL_00103 1.64e-204 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
LHAPMBCL_00104 4.62e-194 - - - K - - - Transcriptional regulator
LHAPMBCL_00105 1.99e-235 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
LHAPMBCL_00106 1.96e-212 ypuA - - S - - - Protein of unknown function (DUF1002)
LHAPMBCL_00107 2.65e-288 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
LHAPMBCL_00108 6.55e-223 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
LHAPMBCL_00109 3.43e-195 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
LHAPMBCL_00110 3.97e-135 - - - S - - - Alpha beta hydrolase
LHAPMBCL_00111 9.92e-34 - - - S - - - Alpha beta hydrolase
LHAPMBCL_00113 4.58e-70 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
LHAPMBCL_00114 3.2e-154 lysR - - K - - - Transcriptional regulator
LHAPMBCL_00115 2.57e-109 - - - C - - - Flavodoxin
LHAPMBCL_00116 2.84e-55 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
LHAPMBCL_00117 2.1e-243 - - - T - - - GHKL domain
LHAPMBCL_00118 4.08e-147 - - - T - - - Transcriptional regulatory protein, C terminal
LHAPMBCL_00119 9e-39 - - - H - - - RibD C-terminal domain
LHAPMBCL_00120 1.43e-95 - - - H - - - RibD C-terminal domain
LHAPMBCL_00121 4.65e-22 - - - - - - - -
LHAPMBCL_00122 1.98e-26 - - - L - - - Addiction module antitoxin, RelB DinJ family
LHAPMBCL_00123 1.97e-277 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
LHAPMBCL_00124 3.5e-220 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
LHAPMBCL_00125 4.38e-210 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
LHAPMBCL_00126 8.56e-161 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
LHAPMBCL_00127 1.39e-195 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LHAPMBCL_00128 2.79e-178 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
LHAPMBCL_00129 2.79e-197 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LHAPMBCL_00130 5.8e-43 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
LHAPMBCL_00131 5.01e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LHAPMBCL_00132 1.66e-170 - - - S - - - Protein of unknown function (DUF1129)
LHAPMBCL_00133 9.74e-154 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LHAPMBCL_00134 3.97e-299 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
LHAPMBCL_00135 5.5e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
LHAPMBCL_00136 3.27e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
LHAPMBCL_00137 3.92e-217 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
LHAPMBCL_00138 6.97e-264 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LHAPMBCL_00139 9.76e-161 vanR - - K - - - response regulator
LHAPMBCL_00140 2.63e-264 hpk31 - - T - - - Histidine kinase
LHAPMBCL_00141 1.97e-185 - - - E - - - AzlC protein
LHAPMBCL_00142 3.33e-69 - - - S - - - branched-chain amino acid
LHAPMBCL_00143 8.81e-169 - - - K - - - LysR substrate binding domain
LHAPMBCL_00144 2.05e-164 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
LHAPMBCL_00145 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LHAPMBCL_00146 3.56e-195 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LHAPMBCL_00147 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
LHAPMBCL_00148 6.72e-111 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
LHAPMBCL_00150 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
LHAPMBCL_00151 1.57e-236 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
LHAPMBCL_00152 0.0 - - - S - - - Bacterial membrane protein, YfhO
LHAPMBCL_00153 3.04e-172 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LHAPMBCL_00154 6.27e-216 - - - I - - - alpha/beta hydrolase fold
LHAPMBCL_00155 1.43e-272 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LHAPMBCL_00156 3.36e-154 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHAPMBCL_00157 1.43e-172 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LHAPMBCL_00158 2.89e-179 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
LHAPMBCL_00159 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
LHAPMBCL_00160 2.5e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LHAPMBCL_00161 4.04e-67 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
LHAPMBCL_00162 8.07e-128 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
LHAPMBCL_00163 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LHAPMBCL_00164 5.98e-265 yacL - - S - - - domain protein
LHAPMBCL_00165 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LHAPMBCL_00166 8.79e-94 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LHAPMBCL_00167 7.41e-175 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LHAPMBCL_00168 9.18e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LHAPMBCL_00169 7.11e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LHAPMBCL_00170 1.1e-126 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
LHAPMBCL_00171 1.39e-92 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LHAPMBCL_00172 3.39e-157 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LHAPMBCL_00173 9.63e-291 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
LHAPMBCL_00175 8.22e-306 - - - M - - - Glycosyl transferase family group 2
LHAPMBCL_00176 6.52e-270 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LHAPMBCL_00177 3.6e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LHAPMBCL_00178 2.46e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LHAPMBCL_00179 2.39e-64 - - - - - - - -
LHAPMBCL_00181 2.32e-62 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LHAPMBCL_00182 6.58e-74 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
LHAPMBCL_00183 7.15e-26 - - - S - - - Protein of unknown function (DUF1700)
LHAPMBCL_00184 6.53e-170 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
LHAPMBCL_00185 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
LHAPMBCL_00186 7.68e-254 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LHAPMBCL_00187 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LHAPMBCL_00188 9.33e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
LHAPMBCL_00189 1.46e-117 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LHAPMBCL_00190 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LHAPMBCL_00191 1.97e-60 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LHAPMBCL_00192 4.92e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LHAPMBCL_00193 4.67e-52 - - - S - - - Protein of unknown function (DUF2508)
LHAPMBCL_00194 1.83e-148 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LHAPMBCL_00195 2.83e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
LHAPMBCL_00196 1.38e-230 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LHAPMBCL_00197 3.71e-76 yabA - - L - - - Involved in initiation control of chromosome replication
LHAPMBCL_00198 4.69e-202 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LHAPMBCL_00199 9.68e-173 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
LHAPMBCL_00200 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
LHAPMBCL_00201 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LHAPMBCL_00202 1.21e-217 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
LHAPMBCL_00203 2.35e-244 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LHAPMBCL_00204 7.04e-160 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
LHAPMBCL_00205 4.12e-133 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
LHAPMBCL_00206 2.77e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LHAPMBCL_00207 1.41e-167 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LHAPMBCL_00208 4.74e-286 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LHAPMBCL_00209 2.46e-175 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LHAPMBCL_00210 1.43e-178 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
LHAPMBCL_00211 2.84e-285 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LHAPMBCL_00212 4.34e-235 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LHAPMBCL_00213 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
LHAPMBCL_00214 4.67e-147 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LHAPMBCL_00215 5.25e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LHAPMBCL_00216 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LHAPMBCL_00219 2.75e-136 - - - K - - - PFAM GCN5-related N-acetyltransferase
LHAPMBCL_00220 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LHAPMBCL_00221 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
LHAPMBCL_00222 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
LHAPMBCL_00223 2.87e-219 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
LHAPMBCL_00224 1.59e-266 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
LHAPMBCL_00225 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
LHAPMBCL_00226 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
LHAPMBCL_00227 1.24e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
LHAPMBCL_00228 2.35e-92 - - - - - - - -
LHAPMBCL_00229 1.24e-112 - - - T - - - Region found in RelA / SpoT proteins
LHAPMBCL_00230 4.12e-149 dltr - - K - - - response regulator
LHAPMBCL_00231 1.32e-267 sptS - - T - - - Histidine kinase
LHAPMBCL_00232 5.36e-270 - - - P - - - Voltage gated chloride channel
LHAPMBCL_00233 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
LHAPMBCL_00234 6.13e-175 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
LHAPMBCL_00235 1.21e-213 - - - C - - - Aldo keto reductase
LHAPMBCL_00236 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
LHAPMBCL_00237 3.77e-113 - - - S - - - ECF-type riboflavin transporter, S component
LHAPMBCL_00238 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
LHAPMBCL_00239 4.02e-237 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LHAPMBCL_00240 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LHAPMBCL_00241 8.17e-120 - - - - - - - -
LHAPMBCL_00242 1.5e-121 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LHAPMBCL_00244 1.45e-145 - - - K - - - Transcriptional regulator, TetR family
LHAPMBCL_00245 2.68e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
LHAPMBCL_00246 1.2e-70 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
LHAPMBCL_00247 5.07e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
LHAPMBCL_00248 7.44e-168 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LHAPMBCL_00249 5.86e-254 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
LHAPMBCL_00250 1.15e-14 - - - J - - - 2'-5' RNA ligase superfamily
LHAPMBCL_00251 2.44e-116 - - - J - - - 2'-5' RNA ligase superfamily
LHAPMBCL_00252 2.27e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
LHAPMBCL_00253 2.24e-92 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LHAPMBCL_00254 5.62e-193 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LHAPMBCL_00255 6.32e-309 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LHAPMBCL_00256 9.49e-57 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LHAPMBCL_00257 1.64e-203 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LHAPMBCL_00258 1.97e-191 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
LHAPMBCL_00259 1.11e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
LHAPMBCL_00260 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
LHAPMBCL_00261 1.23e-69 - - - - - - - -
LHAPMBCL_00262 4.37e-148 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
LHAPMBCL_00263 6.66e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LHAPMBCL_00264 1.22e-270 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LHAPMBCL_00265 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LHAPMBCL_00266 2.37e-221 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LHAPMBCL_00267 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LHAPMBCL_00268 1.74e-167 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
LHAPMBCL_00269 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
LHAPMBCL_00270 1.15e-206 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LHAPMBCL_00271 4.49e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
LHAPMBCL_00272 4.7e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
LHAPMBCL_00273 1.1e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
LHAPMBCL_00274 1.05e-77 yloU - - S - - - Asp23 family, cell envelope-related function
LHAPMBCL_00275 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
LHAPMBCL_00276 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LHAPMBCL_00277 2.24e-239 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LHAPMBCL_00278 1.81e-50 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LHAPMBCL_00279 1.83e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LHAPMBCL_00280 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
LHAPMBCL_00281 4.6e-259 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LHAPMBCL_00282 4.23e-76 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LHAPMBCL_00283 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LHAPMBCL_00284 1.21e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
LHAPMBCL_00285 3.74e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
LHAPMBCL_00286 5.33e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LHAPMBCL_00287 4.49e-182 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
LHAPMBCL_00288 0.0 - - - E ko:K03294 - ko00000 amino acid
LHAPMBCL_00289 3.03e-83 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LHAPMBCL_00290 7.41e-46 - - - - - - - -
LHAPMBCL_00291 1.24e-68 - - - S - - - Mazg nucleotide pyrophosphohydrolase
LHAPMBCL_00294 8.83e-43 ydcH - - S ko:K09794 - ko00000 protein conserved in bacteria
LHAPMBCL_00304 1.27e-102 - - - L - - - Transposase
LHAPMBCL_00305 4.52e-12 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
LHAPMBCL_00307 5.98e-21 ytgB - - S - - - Transglycosylase associated protein
LHAPMBCL_00309 3.33e-92 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
LHAPMBCL_00310 7.19e-50 - - - - - - - -
LHAPMBCL_00314 2.83e-104 asp1 - - S - - - Asp23 family, cell envelope-related function
LHAPMBCL_00315 1.02e-62 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
LHAPMBCL_00318 2.06e-49 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
LHAPMBCL_00319 4.11e-100 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
LHAPMBCL_00320 2.3e-51 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
LHAPMBCL_00321 1.78e-191 csd1 3.5.1.28 - M ko:K01447,ko:K17733,ko:K19117 - ko00000,ko01000,ko01002,ko01011,ko02048 N-Acetylmuramoyl-L-alanine amidase
LHAPMBCL_00322 4.28e-197 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
LHAPMBCL_00323 2.83e-104 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
LHAPMBCL_00324 5.72e-110 - - - K - - - Acetyltransferase (GNAT) domain
LHAPMBCL_00325 2.2e-61 - - - - - - - -
LHAPMBCL_00326 1.04e-209 - - - S - - - reductase
LHAPMBCL_00327 1.81e-30 comA - - V ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LHAPMBCL_00328 4.41e-27 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LHAPMBCL_00329 3.04e-71 - - - - - - - -
LHAPMBCL_00330 1.51e-94 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
LHAPMBCL_00331 2.44e-147 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LHAPMBCL_00333 2.68e-05 - - - K - - - Helix-turn-helix XRE-family like proteins
LHAPMBCL_00336 2.02e-149 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
LHAPMBCL_00337 1.78e-42 - - - - - - - -
LHAPMBCL_00340 1.91e-144 - - - K - - - Transcriptional regulator
LHAPMBCL_00341 5.66e-63 - - - L - - - Belongs to the 'phage' integrase family
LHAPMBCL_00343 8.57e-08 - - - N - - - S-layer homology domain
LHAPMBCL_00346 1.8e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
LHAPMBCL_00347 1.15e-82 asp1 - - S - - - Asp23 family, cell envelope-related function
LHAPMBCL_00348 2.96e-90 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
LHAPMBCL_00349 8.61e-168 - - - IQ - - - dehydrogenase reductase
LHAPMBCL_00350 1.2e-262 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
LHAPMBCL_00351 0.0 eriC - - P ko:K03281 - ko00000 chloride
LHAPMBCL_00352 2.79e-164 - - - L - - - Helix-turn-helix domain
LHAPMBCL_00353 1.11e-201 - - - L ko:K07497 - ko00000 hmm pf00665
LHAPMBCL_00354 2.96e-52 azlC - - E - - - azaleucine resistance protein AzlC
LHAPMBCL_00356 1.79e-33 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LHAPMBCL_00357 4.74e-23 - - - - - - - -
LHAPMBCL_00358 2.11e-45 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
LHAPMBCL_00359 7.06e-146 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
LHAPMBCL_00360 1.02e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LHAPMBCL_00361 4.53e-212 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LHAPMBCL_00362 0.0 - - - O - - - Arylsulfotransferase (ASST)
LHAPMBCL_00363 2.24e-17 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
LHAPMBCL_00364 0.0 sufI - - Q - - - Multicopper oxidase
LHAPMBCL_00365 9.97e-27 - - - T - - - Universal stress protein family
LHAPMBCL_00366 1.48e-293 yhdG - - E ko:K03294 - ko00000 C-terminus of AA_permease
LHAPMBCL_00367 1.94e-05 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
LHAPMBCL_00368 3.53e-232 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
LHAPMBCL_00369 6.63e-232 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
LHAPMBCL_00370 8.22e-288 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
LHAPMBCL_00371 8.23e-117 pgpA - - I - - - Phosphatidylglycerophosphatase A
LHAPMBCL_00374 1.25e-17 - - - - - - - -
LHAPMBCL_00375 5.68e-08 - - - - - - - -
LHAPMBCL_00378 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
LHAPMBCL_00379 7.93e-108 - - - L - - - Transposase and inactivated derivatives, IS30 family
LHAPMBCL_00380 1.25e-208 gpG - - - - - - -
LHAPMBCL_00381 3.98e-108 - - - S - - - Domain of unknown function (DUF4355)
LHAPMBCL_00382 2.66e-35 - - - - - - - -
LHAPMBCL_00383 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
LHAPMBCL_00384 1.93e-150 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
LHAPMBCL_00386 1.34e-127 - - - S ko:K07002 - ko00000 Serine hydrolase
LHAPMBCL_00387 1.26e-82 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
LHAPMBCL_00388 8.69e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LHAPMBCL_00390 1.31e-103 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
LHAPMBCL_00391 1.37e-86 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LHAPMBCL_00392 2.7e-155 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LHAPMBCL_00393 4.68e-233 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LHAPMBCL_00394 8.17e-316 - - - E ko:K03294 - ko00000 amino acid
LHAPMBCL_00395 1.4e-12 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
LHAPMBCL_00396 6.2e-84 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
LHAPMBCL_00397 1.74e-60 - - - - - - - -
LHAPMBCL_00398 4.32e-30 - - - S - - - PFAM Archaeal ATPase
LHAPMBCL_00399 4.82e-221 iolT - - EGP ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LHAPMBCL_00400 2.28e-10 - - - L - - - Transposase
LHAPMBCL_00401 9.74e-99 - - - L - - - Helix-turn-helix domain
LHAPMBCL_00402 8.45e-202 - - - L ko:K07497 - ko00000 hmm pf00665
LHAPMBCL_00403 1.2e-168 - - - L - - - PFAM Integrase, catalytic core
LHAPMBCL_00404 2.22e-171 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
LHAPMBCL_00405 0.0 yclK - - T - - - Histidine kinase
LHAPMBCL_00406 1.29e-198 - - - U ko:K05340 - ko00000,ko02000 sugar transport
LHAPMBCL_00407 9.22e-58 tnpR1 - - L - - - Resolvase, N terminal domain
LHAPMBCL_00408 3.93e-25 - - - - - - - -
LHAPMBCL_00409 1.42e-116 - - - L - - - Initiator Replication protein
LHAPMBCL_00411 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHAPMBCL_00412 9.72e-156 csrR - - K - - - response regulator
LHAPMBCL_00413 7.21e-39 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
LHAPMBCL_00414 4.61e-126 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
LHAPMBCL_00415 9.29e-220 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LHAPMBCL_00416 7.22e-197 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LHAPMBCL_00417 1.29e-150 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
LHAPMBCL_00418 4.67e-146 yjbH - - Q - - - Thioredoxin
LHAPMBCL_00419 2.98e-215 - - - - - - - -
LHAPMBCL_00420 3.95e-127 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LHAPMBCL_00421 8.12e-230 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
LHAPMBCL_00422 1.5e-226 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
LHAPMBCL_00423 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LHAPMBCL_00424 5.63e-145 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
LHAPMBCL_00425 8.67e-122 dpsB - - P - - - Belongs to the Dps family
LHAPMBCL_00426 7.83e-46 - - - C - - - Heavy-metal-associated domain
LHAPMBCL_00427 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
LHAPMBCL_00428 1.06e-276 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LHAPMBCL_00429 1.28e-18 - - - - - - - -
LHAPMBCL_00430 2.93e-198 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LHAPMBCL_00431 9.48e-130 msrA 1.8.4.11 - C ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LHAPMBCL_00432 1.27e-66 yitW - - S - - - Iron-sulfur cluster assembly protein
LHAPMBCL_00433 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
LHAPMBCL_00434 5.1e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
LHAPMBCL_00435 3.65e-308 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
LHAPMBCL_00436 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LHAPMBCL_00437 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LHAPMBCL_00438 2.51e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LHAPMBCL_00439 1.89e-151 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
LHAPMBCL_00440 3.2e-49 - - - - - - - -
LHAPMBCL_00441 6.85e-13 - - - S ko:K07118 - ko00000 NAD(P)H-binding
LHAPMBCL_00442 6.53e-101 - - - S ko:K07118 - ko00000 NAD(P)H-binding
LHAPMBCL_00443 2.3e-52 - - - S - - - Cytochrome b5-like Heme/Steroid binding domain
LHAPMBCL_00444 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
LHAPMBCL_00445 2.97e-156 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LHAPMBCL_00446 0.0 - - - EGP - - - Major Facilitator
LHAPMBCL_00447 3.59e-111 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
LHAPMBCL_00448 1.11e-299 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
LHAPMBCL_00449 8.18e-134 - - - V - - - VanZ like family
LHAPMBCL_00450 7.03e-33 - - - - - - - -
LHAPMBCL_00451 1.64e-72 ytpP - - CO - - - Thioredoxin
LHAPMBCL_00452 9.27e-75 - - - S - - - Small secreted protein
LHAPMBCL_00453 7.19e-150 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
LHAPMBCL_00454 4.48e-231 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
LHAPMBCL_00455 5.18e-134 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LHAPMBCL_00456 1.83e-180 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LHAPMBCL_00457 5.39e-96 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
LHAPMBCL_00459 1.38e-127 - - - K - - - DNA-binding helix-turn-helix protein
LHAPMBCL_00460 1.86e-210 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
LHAPMBCL_00461 1.5e-78 - - - - - - - -
LHAPMBCL_00462 3.76e-269 yttB - - EGP - - - Major Facilitator
LHAPMBCL_00463 1.66e-107 lytE - - M - - - Lysin motif
LHAPMBCL_00464 2.49e-187 - - - S - - - Cof-like hydrolase
LHAPMBCL_00465 1.01e-102 - - - K - - - Transcriptional regulator
LHAPMBCL_00466 0.0 oatA - - I - - - Acyltransferase
LHAPMBCL_00467 1.01e-67 - - - - - - - -
LHAPMBCL_00468 1.3e-284 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LHAPMBCL_00469 5.33e-147 - - - S - - - Calcineurin-like phosphoesterase
LHAPMBCL_00470 9.28e-121 yutD - - S - - - Protein of unknown function (DUF1027)
LHAPMBCL_00471 3.21e-168 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LHAPMBCL_00472 2.52e-132 - - - S - - - Protein of unknown function (DUF1461)
LHAPMBCL_00473 5.25e-149 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
LHAPMBCL_00474 1.25e-113 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LHAPMBCL_00475 4.93e-123 lemA - - S ko:K03744 - ko00000 LemA family
LHAPMBCL_00476 1.51e-203 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
LHAPMBCL_00477 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LHAPMBCL_00478 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LHAPMBCL_00479 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LHAPMBCL_00480 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LHAPMBCL_00481 2.12e-162 ybbR - - S - - - YbbR-like protein
LHAPMBCL_00482 6.61e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LHAPMBCL_00483 3.57e-55 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
LHAPMBCL_00484 0.0 - - - E - - - amino acid
LHAPMBCL_00485 0.0 ydaO - - E - - - amino acid
LHAPMBCL_00486 7.55e-53 - - - - - - - -
LHAPMBCL_00487 1.03e-87 - - - K - - - Transcriptional regulator
LHAPMBCL_00488 1.8e-150 - - - EGP - - - Major Facilitator
LHAPMBCL_00489 2.61e-123 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
LHAPMBCL_00490 3.14e-278 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
LHAPMBCL_00491 5.4e-63 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
LHAPMBCL_00492 5.5e-155 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LHAPMBCL_00493 4.71e-142 yqeK - - H - - - Hydrolase, HD family
LHAPMBCL_00494 3.75e-79 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LHAPMBCL_00495 2.91e-175 yqeM - - Q - - - Methyltransferase
LHAPMBCL_00496 1.08e-268 ylbM - - S - - - Belongs to the UPF0348 family
LHAPMBCL_00497 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LHAPMBCL_00498 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LHAPMBCL_00499 2.17e-245 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
LHAPMBCL_00500 5.03e-95 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
LHAPMBCL_00501 1.98e-110 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
LHAPMBCL_00502 5.14e-268 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
LHAPMBCL_00503 2.39e-311 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
LHAPMBCL_00504 3.74e-26 XK27_07210 - - S - - - B3 4 domain
LHAPMBCL_00505 1.14e-117 - - - - - - - -
LHAPMBCL_00506 4.52e-160 pnb - - C - - - nitroreductase
LHAPMBCL_00507 5.06e-84 XK27_00915 - - C - - - Luciferase-like monooxygenase
LHAPMBCL_00508 5.31e-58 - - - - - - - -
LHAPMBCL_00510 4.44e-91 - - - - - - - -
LHAPMBCL_00511 1.43e-73 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LHAPMBCL_00512 1.85e-120 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
LHAPMBCL_00513 2.27e-134 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
LHAPMBCL_00514 5.27e-281 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
LHAPMBCL_00515 9.17e-131 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
LHAPMBCL_00516 1.53e-266 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
LHAPMBCL_00517 1.88e-60 - - - - - - - -
LHAPMBCL_00518 1.22e-113 - - - J ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
LHAPMBCL_00519 2.23e-71 - - - S - - - Antibiotic biosynthesis monooxygenase
LHAPMBCL_00520 4.26e-46 flp - - V - - - Beta-lactamase
LHAPMBCL_00521 3.87e-46 flp - - V - - - Beta-lactamase
LHAPMBCL_00522 1.2e-111 flp - - V - - - Beta-lactamase
LHAPMBCL_00523 4.31e-123 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
LHAPMBCL_00524 3.41e-159 - - - S ko:K07507 - ko00000,ko02000 MgtC family
LHAPMBCL_00525 5.8e-105 - - - S - - - GyrI-like small molecule binding domain
LHAPMBCL_00527 2.36e-113 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
LHAPMBCL_00528 1.84e-56 azlD - - E - - - Branched-chain amino acid transport
LHAPMBCL_00530 1.08e-266 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
LHAPMBCL_00531 4.51e-54 - - - S - - - Cytochrome B5
LHAPMBCL_00532 8.47e-08 - - - S - - - Cytochrome B5
LHAPMBCL_00533 9.37e-52 - - - S - - - Cytochrome B5
LHAPMBCL_00534 5.81e-96 - - - S ko:K02348 - ko00000 Gnat family
LHAPMBCL_00535 1.84e-155 - - - GM - - - NmrA-like family
LHAPMBCL_00536 1.85e-67 ydeP - - K - - - Transcriptional regulator, HxlR family
LHAPMBCL_00537 3.2e-138 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
LHAPMBCL_00538 1.54e-99 - - - K - - - Transcriptional regulator, HxlR family
LHAPMBCL_00539 8.53e-95 - - - - - - - -
LHAPMBCL_00540 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LHAPMBCL_00541 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
LHAPMBCL_00542 0.0 - - - M - - - domain protein
LHAPMBCL_00543 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
LHAPMBCL_00544 1.62e-279 arcT - - E - - - Aminotransferase
LHAPMBCL_00545 8.23e-215 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
LHAPMBCL_00546 1.92e-102 ykuP - - C ko:K03839 - ko00000 Flavodoxin
LHAPMBCL_00547 1.73e-97 gtcA - - S - - - Teichoic acid glycosylation protein
LHAPMBCL_00548 7.48e-260 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LHAPMBCL_00549 1.43e-47 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
LHAPMBCL_00550 4.68e-187 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
LHAPMBCL_00551 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LHAPMBCL_00552 1.56e-108 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LHAPMBCL_00553 7.58e-134 - - - - - - - -
LHAPMBCL_00554 1.84e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LHAPMBCL_00555 8.01e-228 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
LHAPMBCL_00556 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
LHAPMBCL_00557 1.32e-65 - - - G - - - Right handed beta helix region
LHAPMBCL_00559 9.66e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LHAPMBCL_00560 2.17e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
LHAPMBCL_00561 1.76e-153 - - - G - - - Belongs to the phosphoglycerate mutase family
LHAPMBCL_00562 6.46e-288 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
LHAPMBCL_00563 3.28e-177 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LHAPMBCL_00564 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHAPMBCL_00565 3.82e-316 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LHAPMBCL_00566 0.0 - 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LHAPMBCL_00567 6.17e-44 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Competence-damaged protein
LHAPMBCL_00568 1.15e-52 - - - L ko:K07483 - ko00000 Transposase
LHAPMBCL_00569 1.06e-186 - - - L - - - 4.5 Transposon and IS
LHAPMBCL_00570 1.02e-72 - - - S - - - Iron-sulphur cluster biosynthesis
LHAPMBCL_00571 1.02e-137 - - - I - - - Carboxylesterase family
LHAPMBCL_00572 6.56e-118 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
LHAPMBCL_00573 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
LHAPMBCL_00574 9.01e-231 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
LHAPMBCL_00575 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LHAPMBCL_00576 2.1e-129 - 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
LHAPMBCL_00577 2.92e-265 - 1.5.1.36 - S ko:K19784,ko:K22393,ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
LHAPMBCL_00578 3.27e-224 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LHAPMBCL_00579 1.97e-169 - - - F - - - NUDIX domain
LHAPMBCL_00580 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LHAPMBCL_00581 2.3e-131 pncA - - Q - - - Isochorismatase family
LHAPMBCL_00582 1.3e-263 - - - O - - - ADP-ribosylglycohydrolase
LHAPMBCL_00583 0.0 - - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
LHAPMBCL_00584 4.54e-208 - - - G - - - Belongs to the carbohydrate kinase PfkB family
LHAPMBCL_00585 5.15e-48 hxlR - - K - - - regulation of RNA biosynthetic process
LHAPMBCL_00586 1.28e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
LHAPMBCL_00587 2.42e-261 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LHAPMBCL_00588 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LHAPMBCL_00589 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LHAPMBCL_00590 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
LHAPMBCL_00591 7.41e-108 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LHAPMBCL_00592 7.71e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LHAPMBCL_00593 1.35e-261 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LHAPMBCL_00594 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
LHAPMBCL_00595 2.45e-310 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
LHAPMBCL_00596 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
LHAPMBCL_00597 3.53e-168 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
LHAPMBCL_00598 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
LHAPMBCL_00599 4.55e-315 - - - EGP - - - Major Facilitator
LHAPMBCL_00600 7.7e-144 - - - - - - - -
LHAPMBCL_00603 4.13e-190 - - - S - - - Calcineurin-like phosphoesterase
LHAPMBCL_00604 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
LHAPMBCL_00606 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LHAPMBCL_00607 5.83e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LHAPMBCL_00608 2.28e-270 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
LHAPMBCL_00609 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LHAPMBCL_00610 5.96e-139 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LHAPMBCL_00611 2.09e-150 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
LHAPMBCL_00612 1.07e-103 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K07000,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
LHAPMBCL_00613 5.55e-248 - - - S - - - Protein of unknown function (DUF3114)
LHAPMBCL_00614 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
LHAPMBCL_00615 2.07e-210 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
LHAPMBCL_00616 5.31e-138 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
LHAPMBCL_00617 4.62e-81 - - - S - - - Domain of unknown function (DUF4828)
LHAPMBCL_00618 5.34e-245 mocA - - S - - - Oxidoreductase
LHAPMBCL_00619 4.3e-294 yfmL - - L - - - DEAD DEAH box helicase
LHAPMBCL_00621 9.43e-166 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LHAPMBCL_00622 4.44e-292 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
LHAPMBCL_00623 1.12e-211 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
LHAPMBCL_00624 2.48e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LHAPMBCL_00626 2.6e-156 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
LHAPMBCL_00627 5.58e-192 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
LHAPMBCL_00628 3.25e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
LHAPMBCL_00629 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
LHAPMBCL_00630 1.66e-35 - - - S - - - Psort location CytoplasmicMembrane, score
LHAPMBCL_00632 0.0 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LHAPMBCL_00633 3.88e-206 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LHAPMBCL_00634 1.37e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
LHAPMBCL_00635 7.77e-262 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LHAPMBCL_00636 2.51e-197 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LHAPMBCL_00637 4.88e-261 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
LHAPMBCL_00638 3.85e-197 yvgN - - S - - - Aldo keto reductase
LHAPMBCL_00639 4.09e-131 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
LHAPMBCL_00640 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
LHAPMBCL_00641 2.71e-178 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
LHAPMBCL_00642 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
LHAPMBCL_00643 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LHAPMBCL_00644 3.82e-193 - - - K - - - Helix-turn-helix XRE-family like proteins
LHAPMBCL_00645 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
LHAPMBCL_00646 1.82e-172 gntR - - K - - - UbiC transcription regulator-associated domain protein
LHAPMBCL_00647 4.73e-113 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LHAPMBCL_00648 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LHAPMBCL_00649 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
LHAPMBCL_00650 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
LHAPMBCL_00651 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LHAPMBCL_00652 9.71e-253 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
LHAPMBCL_00654 3.37e-222 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LHAPMBCL_00656 3.36e-77 - - - - - - - -
LHAPMBCL_00657 1.62e-229 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
LHAPMBCL_00658 1.08e-161 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LHAPMBCL_00659 3.95e-71 - - - - - - - -
LHAPMBCL_00660 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LHAPMBCL_00661 8.59e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LHAPMBCL_00662 5.3e-291 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LHAPMBCL_00663 2.55e-219 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
LHAPMBCL_00664 1.51e-32 - - - - - - - -
LHAPMBCL_00665 9.1e-141 - - - - - - - -
LHAPMBCL_00666 2.65e-137 yttB - - EGP - - - Major Facilitator
LHAPMBCL_00667 5.36e-61 yttB - - EGP - - - Major Facilitator
LHAPMBCL_00668 3.7e-32 yttB - - EGP - - - Major Facilitator
LHAPMBCL_00669 4.61e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
LHAPMBCL_00670 6.28e-116 - - - - - - - -
LHAPMBCL_00671 4.3e-142 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
LHAPMBCL_00672 6.91e-137 - - - S - - - Putative peptidoglycan binding domain
LHAPMBCL_00673 6.26e-24 - - - S - - - Putative peptidoglycan binding domain
LHAPMBCL_00674 5.69e-44 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
LHAPMBCL_00675 2.48e-129 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
LHAPMBCL_00676 4.49e-26 - - - - - - - -
LHAPMBCL_00677 2.3e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LHAPMBCL_00678 1.01e-274 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
LHAPMBCL_00679 5.58e-76 XK27_04120 - - S - - - Putative amino acid metabolism
LHAPMBCL_00680 3.57e-285 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LHAPMBCL_00681 5.48e-157 pgm6 - - G - - - phosphoglycerate mutase
LHAPMBCL_00682 1.49e-154 - - - S - - - repeat protein
LHAPMBCL_00683 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LHAPMBCL_00684 7.04e-222 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LHAPMBCL_00685 0.0 potE - - E - - - Amino Acid
LHAPMBCL_00686 3.25e-292 - - - V - - - MatE
LHAPMBCL_00687 3.88e-92 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
LHAPMBCL_00688 3.89e-215 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LHAPMBCL_00689 2.36e-56 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
LHAPMBCL_00690 5.46e-186 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LHAPMBCL_00691 7.57e-119 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
LHAPMBCL_00692 5.79e-78 yodB - - K - - - Transcriptional regulator, HxlR family
LHAPMBCL_00693 3.01e-251 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LHAPMBCL_00694 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LHAPMBCL_00695 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LHAPMBCL_00696 1.42e-214 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
LHAPMBCL_00697 1.9e-139 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LHAPMBCL_00698 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LHAPMBCL_00699 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LHAPMBCL_00700 3.29e-109 - - - F - - - NUDIX domain
LHAPMBCL_00701 1.81e-222 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
LHAPMBCL_00702 1.5e-88 - - - S - - - Belongs to the HesB IscA family
LHAPMBCL_00703 2.79e-89 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LHAPMBCL_00704 7.09e-184 - - - S - - - DUF218 domain
LHAPMBCL_00705 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
LHAPMBCL_00706 1.19e-315 yhdP - - S - - - Transporter associated domain
LHAPMBCL_00707 1.55e-94 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
LHAPMBCL_00708 2.27e-306 - - - U - - - Belongs to the major facilitator superfamily
LHAPMBCL_00709 3.8e-58 - - - S - - - UPF0756 membrane protein
LHAPMBCL_00710 5.05e-103 - - - S - - - Cupin domain
LHAPMBCL_00711 2.23e-35 - - - C - - - Flavodoxin
LHAPMBCL_00712 3.05e-121 - - - K - - - Acetyltransferase (GNAT) domain
LHAPMBCL_00713 3.87e-202 - - - S - - - Alpha beta hydrolase
LHAPMBCL_00714 3.85e-198 gspA - - M - - - family 8
LHAPMBCL_00715 7.18e-153 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
LHAPMBCL_00716 1e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
LHAPMBCL_00717 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
LHAPMBCL_00718 1e-166 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LHAPMBCL_00719 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LHAPMBCL_00720 8.25e-218 - - - G - - - Phosphotransferase enzyme family
LHAPMBCL_00721 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
LHAPMBCL_00722 1.01e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LHAPMBCL_00723 2.16e-212 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LHAPMBCL_00724 2.27e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
LHAPMBCL_00725 6.15e-132 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LHAPMBCL_00726 6.13e-100 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
LHAPMBCL_00727 1.97e-07 - - - K - - - Helix-turn-helix XRE-family like proteins
LHAPMBCL_00731 6.93e-60 - - - S - - - Domain of unknown function (DUF4868)
LHAPMBCL_00732 2.96e-107 - - - - - - - -
LHAPMBCL_00734 1.56e-78 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
LHAPMBCL_00735 8.29e-77 - - - L - - - HNH nucleases
LHAPMBCL_00736 2.37e-82 - - - L - - - Phage terminase, small subunit
LHAPMBCL_00737 0.0 terL - - S - - - overlaps another CDS with the same product name
LHAPMBCL_00739 1.22e-272 - - - S - - - Phage portal protein
LHAPMBCL_00740 2.07e-153 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
LHAPMBCL_00741 1.73e-240 - - - S - - - Phage capsid family
LHAPMBCL_00742 5.79e-54 - - - S - - - Phage gp6-like head-tail connector protein
LHAPMBCL_00744 1.32e-40 - - - S - - - exonuclease activity
LHAPMBCL_00746 1.21e-101 - - - S - - - Phage tail tube protein
LHAPMBCL_00749 2.05e-156 - - - L - - - Phage tail tape measure protein TP901
LHAPMBCL_00750 9.75e-105 - - - S - - - Phage tail protein
LHAPMBCL_00751 1.1e-170 - - - M - - - Prophage endopeptidase tail
LHAPMBCL_00752 1.5e-48 - - - LM - - - gp58-like protein
LHAPMBCL_00759 5.75e-44 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
LHAPMBCL_00760 5.88e-185 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
LHAPMBCL_00761 2.39e-13 - - - T - - - SpoVT / AbrB like domain
LHAPMBCL_00762 3.62e-31 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
LHAPMBCL_00763 1.95e-109 uspA - - T - - - universal stress protein
LHAPMBCL_00764 5.13e-61 - - - - - - - -
LHAPMBCL_00765 2.56e-307 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
LHAPMBCL_00766 1.95e-109 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
LHAPMBCL_00767 3.56e-29 - - - - - - - -
LHAPMBCL_00768 2.34e-97 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
LHAPMBCL_00769 3.42e-179 - - - S - - - Membrane
LHAPMBCL_00770 8.05e-179 - - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
LHAPMBCL_00771 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
LHAPMBCL_00772 0.0 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
LHAPMBCL_00773 7.86e-301 pbuG - - S ko:K06901 - ko00000,ko02000 permease
LHAPMBCL_00774 1.31e-35 - - - EGP - - - Major Facilitator
LHAPMBCL_00775 2.55e-42 - - - EGP - - - Major Facilitator
LHAPMBCL_00776 3.16e-143 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
LHAPMBCL_00777 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
LHAPMBCL_00778 1.65e-145 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
LHAPMBCL_00779 3.24e-120 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LHAPMBCL_00780 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LHAPMBCL_00781 8.75e-236 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LHAPMBCL_00782 4.99e-65 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
LHAPMBCL_00783 1.88e-68 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
LHAPMBCL_00784 1.61e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LHAPMBCL_00785 1.2e-202 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LHAPMBCL_00786 2.41e-236 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
LHAPMBCL_00787 1.08e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LHAPMBCL_00788 3.04e-176 lutC - - S ko:K00782 - ko00000 LUD domain
LHAPMBCL_00789 1.21e-178 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
LHAPMBCL_00790 1.33e-166 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
LHAPMBCL_00791 1.25e-202 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
LHAPMBCL_00792 4.79e-222 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LHAPMBCL_00793 3.93e-270 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
LHAPMBCL_00794 4.7e-205 - - - ET ko:K02030 - ko00000,ko00002,ko02000 PFAM extracellular solute-binding protein, family 3
LHAPMBCL_00795 2.74e-112 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
LHAPMBCL_00796 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
LHAPMBCL_00797 3.57e-150 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
LHAPMBCL_00798 2.12e-19 - - - - - - - -
LHAPMBCL_00799 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LHAPMBCL_00800 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LHAPMBCL_00801 3.12e-315 steT - - E ko:K03294 - ko00000 amino acid
LHAPMBCL_00802 2.21e-205 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
LHAPMBCL_00803 4.03e-239 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
LHAPMBCL_00804 1.94e-218 whiA - - K ko:K09762 - ko00000 May be required for sporulation
LHAPMBCL_00806 1.83e-21 - - - - - - - -
LHAPMBCL_00807 2.37e-307 glpT - - G ko:K02445 - ko00000,ko02000 Major Facilitator Superfamily
LHAPMBCL_00808 2.73e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LHAPMBCL_00810 1.31e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LHAPMBCL_00811 3.1e-289 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
LHAPMBCL_00812 2.51e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LHAPMBCL_00813 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LHAPMBCL_00814 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
LHAPMBCL_00815 2.18e-133 - - - M - - - LysM domain protein
LHAPMBCL_00816 2.61e-203 - - - O - - - Uncharacterized protein family (UPF0051)
LHAPMBCL_00817 2.28e-143 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LHAPMBCL_00818 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
LHAPMBCL_00819 2.22e-269 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
LHAPMBCL_00820 9.66e-123 - - - K - - - Acetyltransferase (GNAT) domain
LHAPMBCL_00821 8.63e-20 - - - E - - - Zn peptidase
LHAPMBCL_00824 2.05e-83 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
LHAPMBCL_00825 2.82e-183 - - - L ko:K07484 - ko00000 Transposase IS66 family
LHAPMBCL_00826 1.27e-183 - - - L ko:K07484 - ko00000 Transposase IS66 family
LHAPMBCL_00828 2.56e-249 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
LHAPMBCL_00829 1.92e-204 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
LHAPMBCL_00830 5.33e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LHAPMBCL_00831 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LHAPMBCL_00832 4.47e-16 - - - S - - - Protein of unknown function (DUF4044)
LHAPMBCL_00833 8.07e-76 - - - - - - - -
LHAPMBCL_00834 3.43e-184 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
LHAPMBCL_00836 5.62e-93 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
LHAPMBCL_00837 1.97e-53 - - - S - - - Protein of unknown function (DUF1797)
LHAPMBCL_00838 1.48e-225 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LHAPMBCL_00839 4.62e-252 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
LHAPMBCL_00840 7.34e-290 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
LHAPMBCL_00841 4.56e-34 - - - S - - - Protein of unknown function (DUF1064)
LHAPMBCL_00842 0.0 csd1 3.5.1.28 - M ko:K01447,ko:K17733,ko:K19117 - ko00000,ko01000,ko01002,ko01011,ko02048 N-Acetylmuramoyl-L-alanine amidase
LHAPMBCL_00843 1.31e-232 yueF - - S - - - AI-2E family transporter
LHAPMBCL_00844 2.65e-298 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LHAPMBCL_00845 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LHAPMBCL_00846 2.53e-26 - - - M - - - NlpC/P60 family
LHAPMBCL_00847 0.0 - - - M - - - NlpC/P60 family
LHAPMBCL_00848 0.0 - - - S - - - Peptidase, M23
LHAPMBCL_00849 0.0 - - - S - - - Peptidase, M23
LHAPMBCL_00850 1.7e-84 - - - K - - - Transcriptional regulator, GntR family
LHAPMBCL_00851 1.91e-201 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHAPMBCL_00852 5.78e-148 - - - - - - - -
LHAPMBCL_00853 1.35e-182 - - - G - - - MucBP domain
LHAPMBCL_00854 3.15e-130 - - - S - - - Pfam:DUF3816
LHAPMBCL_00855 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
LHAPMBCL_00856 1.38e-37 - - - - - - - -
LHAPMBCL_00857 3.69e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
LHAPMBCL_00858 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LHAPMBCL_00859 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LHAPMBCL_00860 1.34e-147 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
LHAPMBCL_00861 3.31e-162 pgm3 - - G - - - phosphoglycerate mutase
LHAPMBCL_00862 9.37e-294 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LHAPMBCL_00863 4.67e-11 - - - - - - - -
LHAPMBCL_00865 0.000841 - - - - - - - -
LHAPMBCL_00866 1.41e-68 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
LHAPMBCL_00874 1.33e-136 int3 - - L - - - Belongs to the 'phage' integrase family
LHAPMBCL_00876 8.29e-142 - - - S - - - Domain of unknown function (DUF4393)
LHAPMBCL_00878 8.91e-40 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
LHAPMBCL_00879 2.17e-97 - - - K - - - Peptidase S24-like
LHAPMBCL_00880 5.35e-06 - - - K - - - Helix-turn-helix XRE-family like proteins
LHAPMBCL_00881 6.96e-77 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
LHAPMBCL_00890 2.71e-66 - - - S - - - ERF superfamily
LHAPMBCL_00891 4.5e-15 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
LHAPMBCL_00892 2.36e-88 - - - L - - - DnaD domain protein
LHAPMBCL_00893 7.28e-45 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
LHAPMBCL_00895 3.08e-165 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
LHAPMBCL_00896 3.26e-178 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
LHAPMBCL_00897 1.98e-182 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LHAPMBCL_00898 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
LHAPMBCL_00899 5.61e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LHAPMBCL_00900 4.19e-96 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LHAPMBCL_00901 5.75e-285 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LHAPMBCL_00902 4.98e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
LHAPMBCL_00903 6.27e-200 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
LHAPMBCL_00904 7.21e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LHAPMBCL_00905 1.36e-219 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LHAPMBCL_00906 2.35e-101 - - - K - - - Transcriptional regulator, MarR family
LHAPMBCL_00907 1.76e-94 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LHAPMBCL_00909 1.19e-258 xerS - - L - - - Belongs to the 'phage' integrase family
LHAPMBCL_00910 1.97e-39 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
LHAPMBCL_00911 5.69e-234 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
LHAPMBCL_00912 2.42e-202 rssA - - S - - - Phospholipase, patatin family
LHAPMBCL_00913 1.15e-152 - - - L - - - Integrase
LHAPMBCL_00914 0.0 - - - S - - - SEC-C Motif Domain Protein
LHAPMBCL_00915 6.11e-68 - - - - - - - -
LHAPMBCL_00916 2.37e-181 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LHAPMBCL_00917 2.76e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LHAPMBCL_00918 3.17e-150 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LHAPMBCL_00919 1.38e-292 - - - P - - - Chloride transporter, ClC family
LHAPMBCL_00920 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
LHAPMBCL_00921 6.88e-144 - - - I - - - Acid phosphatase homologues
LHAPMBCL_00923 1.19e-66 - - - - - - - -
LHAPMBCL_00924 4.33e-259 - - - - - - - -
LHAPMBCL_00925 7.86e-106 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LHAPMBCL_00926 2.39e-176 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
LHAPMBCL_00927 3.94e-75 yvgN - - S - - - Aldo keto reductase
LHAPMBCL_00928 7.6e-286 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
LHAPMBCL_00929 1.16e-200 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
LHAPMBCL_00930 2.16e-212 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LHAPMBCL_00931 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LHAPMBCL_00932 1.29e-199 - - - EGP - - - Major Facilitator
LHAPMBCL_00933 4.31e-33 - - - EGP - - - Major Facilitator
LHAPMBCL_00934 3.1e-115 ymdB - - S - - - Macro domain protein
LHAPMBCL_00935 2.49e-141 - - - K - - - Helix-turn-helix domain
LHAPMBCL_00936 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
LHAPMBCL_00937 1.48e-64 - - - - - - - -
LHAPMBCL_00938 2.5e-296 - - - S - - - Putative metallopeptidase domain
LHAPMBCL_00939 1.98e-259 - - - S - - - associated with various cellular activities
LHAPMBCL_00940 1.11e-152 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
LHAPMBCL_00941 2.63e-84 yeaO - - S - - - Protein of unknown function, DUF488
LHAPMBCL_00943 2.37e-151 yrkL - - S - - - Flavodoxin-like fold
LHAPMBCL_00944 3.32e-72 - - - - - - - -
LHAPMBCL_00946 1.76e-12 - 2.1.1.72 - D ko:K03427 - ko00000,ko01000,ko02048 peptidase
LHAPMBCL_00947 1.25e-28 - - - S - - - PD-(D/E)XK nuclease family transposase
LHAPMBCL_00948 2.48e-66 - - - - - - - -
LHAPMBCL_00949 3.42e-258 yngD - - S ko:K07097 - ko00000 DHHA1 domain
LHAPMBCL_00950 4.27e-292 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
LHAPMBCL_00951 9.02e-317 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LHAPMBCL_00952 6.99e-136 - - - NU - - - mannosyl-glycoprotein
LHAPMBCL_00953 7.71e-182 - - - S - - - Putative ABC-transporter type IV
LHAPMBCL_00954 0.0 - - - S - - - ABC transporter, ATP-binding protein
LHAPMBCL_00955 6.32e-171 - - - M - - - PFAM NLP P60 protein
LHAPMBCL_00956 3.69e-232 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
LHAPMBCL_00957 6.8e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LHAPMBCL_00958 2.11e-172 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHAPMBCL_00959 4.74e-120 - - - P - - - Cadmium resistance transporter
LHAPMBCL_00960 1.33e-73 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
LHAPMBCL_00961 4.19e-300 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
LHAPMBCL_00962 6.22e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LHAPMBCL_00963 1.08e-168 yceF - - P ko:K05794 - ko00000 membrane
LHAPMBCL_00964 4.92e-213 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LHAPMBCL_00965 1.52e-211 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
LHAPMBCL_00966 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LHAPMBCL_00967 4.79e-307 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
LHAPMBCL_00968 5.67e-315 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
LHAPMBCL_00969 4.97e-115 - - - S - - - C4-dicarboxylate anaerobic carrier
LHAPMBCL_00970 3.12e-193 - - - S - - - C4-dicarboxylate anaerobic carrier
LHAPMBCL_00971 1.64e-162 pgm3 - - G - - - phosphoglycerate mutase family
LHAPMBCL_00972 7.2e-56 - - - - - - - -
LHAPMBCL_00973 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LHAPMBCL_00974 9.11e-261 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
LHAPMBCL_00975 6.69e-168 - - - S - - - Alpha beta hydrolase
LHAPMBCL_00976 2.5e-243 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LHAPMBCL_00977 6.68e-14 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LHAPMBCL_00978 2.26e-130 - - - - - - - -
LHAPMBCL_00983 2.29e-30 - - - M - - - CHAP domain
LHAPMBCL_00985 3.02e-123 - - - S - - - peptidoglycan catabolic process
LHAPMBCL_00986 6.68e-46 - - - S - - - Bacteriophage Gp15 protein
LHAPMBCL_00988 3.7e-51 - - - N - - - domain, Protein
LHAPMBCL_00991 3.07e-38 - - - S - - - Minor capsid protein
LHAPMBCL_00993 2.86e-131 - - - - - - - -
LHAPMBCL_00994 6.52e-17 - - - S - - - Phage minor structural protein GP20
LHAPMBCL_00995 2.8e-114 - - - S - - - Phage minor capsid protein 2
LHAPMBCL_00996 1.26e-164 - - - S - - - Phage portal protein, SPP1 Gp6-like
LHAPMBCL_00997 2.5e-172 - - - S - - - Pfam:Terminase_3C
LHAPMBCL_00998 1.24e-60 - - - - - - - -
LHAPMBCL_01000 1.75e-33 - - - - - - - -
LHAPMBCL_01001 2.09e-86 - - - K - - - Protein of unknown function (DUF4065)
LHAPMBCL_01004 8.05e-146 - - - M - - - Glycosyl hydrolases family 25
LHAPMBCL_01005 7.58e-251 - - - M - - - Prophage endopeptidase tail
LHAPMBCL_01006 2.51e-130 - - - S - - - Phage tail protein
LHAPMBCL_01007 0.0 - - - D - - - domain protein
LHAPMBCL_01010 4.23e-105 - - - - - - - -
LHAPMBCL_01011 4.81e-55 - - - - - - - -
LHAPMBCL_01012 5.3e-83 - - - - - - - -
LHAPMBCL_01013 1.74e-38 - - - - - - - -
LHAPMBCL_01014 1.14e-61 - - - S - - - Phage gp6-like head-tail connector protein
LHAPMBCL_01015 4.1e-182 - - - - - - - -
LHAPMBCL_01016 1.57e-68 - - - S - - - Domain of unknown function (DUF4355)
LHAPMBCL_01018 2.37e-133 - - - S - - - Phage Mu protein F like protein
LHAPMBCL_01019 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
LHAPMBCL_01020 1.68e-214 - - - S - - - Terminase-like family
LHAPMBCL_01021 7.51e-80 - - - L ko:K07474 - ko00000 Terminase small subunit
LHAPMBCL_01022 1.03e-114 - - - L - - - DNA methylase
LHAPMBCL_01025 6.34e-55 - - - S - - - Protein of unknown function (DUF4065)
LHAPMBCL_01026 2.79e-224 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
LHAPMBCL_01027 6.94e-138 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LHAPMBCL_01033 9.12e-62 - - - K ko:K07741 - ko00000 AntA/AntB antirepressor
LHAPMBCL_01035 1.21e-21 - - - K - - - sequence-specific DNA binding
LHAPMBCL_01037 5.06e-31 - - - S - - - Short C-terminal domain
LHAPMBCL_01040 4.92e-167 - - - S - - - Recombinase
LHAPMBCL_01041 7.89e-123 - - - L - - - Transposase
LHAPMBCL_01042 8.57e-87 - - - S - - - Domain of unknown function (DUF4767)
LHAPMBCL_01043 3.7e-19 - - - - - - - -
LHAPMBCL_01044 5.71e-263 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
LHAPMBCL_01045 3.16e-121 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
LHAPMBCL_01046 4.89e-122 - - - K - - - PFAM GCN5-related N-acetyltransferase
LHAPMBCL_01047 2.32e-104 - - - - - - - -
LHAPMBCL_01048 5.52e-168 - - - M - - - Lysin motif
LHAPMBCL_01049 7.33e-253 - - - EGP - - - Major Facilitator
LHAPMBCL_01050 2.77e-306 - - - E - - - amino acid
LHAPMBCL_01051 1.02e-176 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
LHAPMBCL_01052 1.8e-306 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LHAPMBCL_01053 1.47e-211 - - - GK - - - ROK family
LHAPMBCL_01054 0.0 fusA1 - - J - - - elongation factor G
LHAPMBCL_01055 3.96e-65 fusA1 - - J - - - elongation factor G
LHAPMBCL_01056 7.46e-106 uspA3 - - T - - - universal stress protein
LHAPMBCL_01057 4.97e-249 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
LHAPMBCL_01058 1.78e-83 - - - - - - - -
LHAPMBCL_01059 4.39e-11 - - - - - - - -
LHAPMBCL_01060 3.96e-58 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
LHAPMBCL_01061 3.35e-12 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
LHAPMBCL_01062 4.36e-173 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LHAPMBCL_01063 1.08e-267 - - - EGP - - - Major Facilitator
LHAPMBCL_01064 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
LHAPMBCL_01065 5e-41 - - - C - - - Zinc-binding dehydrogenase
LHAPMBCL_01066 2.28e-41 - - - C - - - Zinc-binding dehydrogenase
LHAPMBCL_01067 1.35e-204 - - - - - - - -
LHAPMBCL_01068 1.3e-95 - - - K - - - Transcriptional regulator
LHAPMBCL_01069 1.71e-239 ybcH - - D ko:K06889 - ko00000 Alpha beta
LHAPMBCL_01070 1.82e-68 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
LHAPMBCL_01071 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
LHAPMBCL_01072 5.35e-70 - - - - - - - -
LHAPMBCL_01073 9.34e-144 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
LHAPMBCL_01074 7.1e-309 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LHAPMBCL_01075 3.5e-126 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
LHAPMBCL_01076 8.5e-171 - - - S ko:K07090 - ko00000 membrane transporter protein
LHAPMBCL_01077 1.1e-177 - - - IQ - - - KR domain
LHAPMBCL_01078 6.65e-234 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
LHAPMBCL_01079 3.14e-229 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
LHAPMBCL_01080 1.39e-63 - - - S - - - Double zinc ribbon
LHAPMBCL_01081 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
LHAPMBCL_01082 4.67e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
LHAPMBCL_01083 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
LHAPMBCL_01084 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LHAPMBCL_01085 1.01e-291 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LHAPMBCL_01086 1.26e-304 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
LHAPMBCL_01087 6.98e-156 radC - - L ko:K03630 - ko00000 DNA repair protein
LHAPMBCL_01088 3.39e-229 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
LHAPMBCL_01089 2.12e-192 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
LHAPMBCL_01090 1.69e-120 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
LHAPMBCL_01091 8.97e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
LHAPMBCL_01092 2.06e-151 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LHAPMBCL_01093 1.92e-203 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
LHAPMBCL_01094 8.29e-292 ymfF - - S - - - Peptidase M16 inactive domain protein
LHAPMBCL_01095 1.25e-315 ymfH - - S - - - Peptidase M16
LHAPMBCL_01096 5.32e-200 - - - S - - - Helix-turn-helix domain
LHAPMBCL_01097 1.36e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LHAPMBCL_01098 6.25e-287 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
LHAPMBCL_01099 2.2e-251 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LHAPMBCL_01100 1.46e-272 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
LHAPMBCL_01101 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LHAPMBCL_01102 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LHAPMBCL_01103 8.76e-131 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LHAPMBCL_01104 1.16e-243 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LHAPMBCL_01105 8.04e-238 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LHAPMBCL_01106 3.56e-60 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
LHAPMBCL_01107 6.15e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
LHAPMBCL_01108 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LHAPMBCL_01109 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LHAPMBCL_01110 1.34e-56 yrzL - - S - - - Belongs to the UPF0297 family
LHAPMBCL_01111 3.62e-100 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LHAPMBCL_01112 3.75e-63 yrzB - - S - - - Belongs to the UPF0473 family
LHAPMBCL_01113 7.15e-122 cvpA - - S - - - Colicin V production protein
LHAPMBCL_01114 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LHAPMBCL_01115 2.86e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LHAPMBCL_01116 3.51e-125 yslB - - S - - - Protein of unknown function (DUF2507)
LHAPMBCL_01117 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
LHAPMBCL_01118 3.19e-67 - - - M - - - LPXTG-motif cell wall anchor domain protein
LHAPMBCL_01119 1.57e-219 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LHAPMBCL_01120 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LHAPMBCL_01121 7.68e-310 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LHAPMBCL_01122 1.03e-108 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LHAPMBCL_01123 6.66e-283 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LHAPMBCL_01124 2.11e-219 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LHAPMBCL_01125 1.05e-179 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LHAPMBCL_01126 3.82e-275 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LHAPMBCL_01127 7.41e-254 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LHAPMBCL_01128 1.86e-64 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
LHAPMBCL_01129 2.51e-74 - - - - - - - -
LHAPMBCL_01131 1.66e-247 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
LHAPMBCL_01132 8.83e-39 - - - - - - - -
LHAPMBCL_01133 7.47e-233 - - - I - - - Diacylglycerol kinase catalytic
LHAPMBCL_01134 9.99e-44 ykzG - - S - - - Belongs to the UPF0356 family
LHAPMBCL_01135 2.3e-106 - - - - - - - -
LHAPMBCL_01136 1.68e-133 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LHAPMBCL_01137 9.95e-267 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
LHAPMBCL_01138 1.9e-231 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
LHAPMBCL_01139 3.53e-310 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LHAPMBCL_01140 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
LHAPMBCL_01141 7.04e-63 yktA - - S - - - Belongs to the UPF0223 family
LHAPMBCL_01142 2.37e-175 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
LHAPMBCL_01143 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
LHAPMBCL_01144 9.19e-285 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LHAPMBCL_01145 5.25e-59 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
LHAPMBCL_01146 2.37e-129 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
LHAPMBCL_01147 1.76e-115 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LHAPMBCL_01148 1.74e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
LHAPMBCL_01149 1.14e-136 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
LHAPMBCL_01150 8.3e-115 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
LHAPMBCL_01151 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
LHAPMBCL_01152 3.61e-190 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
LHAPMBCL_01153 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
LHAPMBCL_01154 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LHAPMBCL_01155 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LHAPMBCL_01156 8.43e-207 - - - S - - - Tetratricopeptide repeat
LHAPMBCL_01157 4.94e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LHAPMBCL_01158 1.85e-301 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LHAPMBCL_01159 5.9e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LHAPMBCL_01160 8.21e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
LHAPMBCL_01161 1.11e-78 - - - S - - - mazG nucleotide pyrophosphohydrolase
LHAPMBCL_01162 2.44e-20 - - - - - - - -
LHAPMBCL_01163 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LHAPMBCL_01164 1.9e-316 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LHAPMBCL_01165 2.39e-226 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LHAPMBCL_01166 1.84e-198 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LHAPMBCL_01167 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
LHAPMBCL_01168 1.25e-119 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LHAPMBCL_01169 1.53e-122 - - - - - - - -
LHAPMBCL_01170 4.4e-208 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
LHAPMBCL_01171 5.89e-171 - - - I - - - alpha/beta hydrolase fold
LHAPMBCL_01172 4e-127 - - - S - - - Conserved hypothetical protein 698
LHAPMBCL_01173 1.6e-73 - - - S - - - Conserved hypothetical protein 698
LHAPMBCL_01174 3.4e-120 - - - S - - - NADPH-dependent FMN reductase
LHAPMBCL_01175 1.72e-212 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LHAPMBCL_01176 8.65e-310 yhdP - - S - - - Transporter associated domain
LHAPMBCL_01177 1.02e-200 - - - V - - - (ABC) transporter
LHAPMBCL_01178 5.68e-117 - - - GM - - - epimerase
LHAPMBCL_01179 1.06e-117 - - - K - - - Domain of unknown function (DUF1836)
LHAPMBCL_01180 8.16e-103 yybA - - K - - - Transcriptional regulator
LHAPMBCL_01181 1.44e-168 XK27_07210 - - S - - - B3 4 domain
LHAPMBCL_01182 1.17e-234 XK27_12525 - - S - - - AI-2E family transporter
LHAPMBCL_01183 1.63e-198 - - - G - - - Xylose isomerase domain protein TIM barrel
LHAPMBCL_01184 1.51e-202 - - - - - - - -
LHAPMBCL_01185 1.7e-173 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LHAPMBCL_01186 1.92e-240 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LHAPMBCL_01187 5.43e-29 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
LHAPMBCL_01189 4.98e-27 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
LHAPMBCL_01190 2.65e-23 - - - S - - - HNH endonuclease
LHAPMBCL_01191 1.03e-97 - - - P - - - Major Facilitator Superfamily
LHAPMBCL_01192 4.35e-26 - - - - - - - -
LHAPMBCL_01193 3.87e-151 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
LHAPMBCL_01194 6.23e-115 - - - L - - - Belongs to the 'phage' integrase family
LHAPMBCL_01198 9.69e-50 - - - K - - - Helix-turn-helix domain
LHAPMBCL_01199 2.36e-84 - - - S - - - DNA binding
LHAPMBCL_01209 4.25e-187 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
LHAPMBCL_01210 2.03e-78 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
LHAPMBCL_01211 8.94e-274 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
LHAPMBCL_01212 4.36e-102 - - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LHAPMBCL_01213 1.18e-140 yvrI - - K ko:K03091,ko:K03093 - ko00000,ko03021 sigma factor activity
LHAPMBCL_01214 2.69e-259 - - - G - - - Transporter, major facilitator family protein
LHAPMBCL_01215 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
LHAPMBCL_01216 3.66e-146 - - - T ko:K10716 - ko00000,ko02000 Ion transport 2 domain protein
LHAPMBCL_01217 5.28e-100 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LHAPMBCL_01218 3.44e-282 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
LHAPMBCL_01219 3.11e-120 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
LHAPMBCL_01220 6e-228 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LHAPMBCL_01221 7.42e-228 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
LHAPMBCL_01223 0.0 - - - L - - - PLD-like domain
LHAPMBCL_01224 1.48e-26 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
LHAPMBCL_01226 5.31e-115 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LHAPMBCL_01227 2.83e-91 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
LHAPMBCL_01228 2.61e-73 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
LHAPMBCL_01229 8.02e-34 - - - K - - - TRANSCRIPTIONal
LHAPMBCL_01230 2.01e-07 - - - K - - - TRANSCRIPTIONal
LHAPMBCL_01231 3.08e-81 yju3 - - I - - - Serine aminopeptidase, S33
LHAPMBCL_01232 1.56e-102 pncA - - Q - - - Isochorismatase family
LHAPMBCL_01233 1.26e-263 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LHAPMBCL_01234 1.38e-106 - - - F - - - NUDIX domain
LHAPMBCL_01235 7.11e-71 - - - S - - - Phage portal protein
LHAPMBCL_01236 7.09e-134 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
LHAPMBCL_01237 4.48e-34 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
LHAPMBCL_01238 3.09e-104 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
LHAPMBCL_01239 4.88e-59 - - - DJ - - - ParE toxin of type II toxin-antitoxin system, parDE
LHAPMBCL_01240 7.37e-37 - - - - - - - -
LHAPMBCL_01241 6.62e-242 - - - S - - - overlaps another CDS with the same product name
LHAPMBCL_01242 1.03e-215 - - - L - - - Plasmid pRiA4b ORF-3-like protein
LHAPMBCL_01243 1.62e-74 - - - H - - - Riboflavin biosynthesis protein RibD
LHAPMBCL_01244 7.3e-118 - - - S - - - PFAM Archaeal ATPase
LHAPMBCL_01245 4.08e-39 cspA - - K ko:K03704 - ko00000,ko03000 Cold shock protein
LHAPMBCL_01247 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LHAPMBCL_01248 7.79e-237 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
LHAPMBCL_01249 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LHAPMBCL_01250 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LHAPMBCL_01251 2.26e-65 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LHAPMBCL_01252 1.11e-260 camS - - S - - - sex pheromone
LHAPMBCL_01253 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LHAPMBCL_01254 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
LHAPMBCL_01255 1.32e-271 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LHAPMBCL_01256 7.9e-130 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LHAPMBCL_01257 5.95e-147 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
LHAPMBCL_01258 1.56e-180 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
LHAPMBCL_01259 3.24e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
LHAPMBCL_01260 9.25e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LHAPMBCL_01261 2.05e-180 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LHAPMBCL_01262 2.77e-179 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LHAPMBCL_01263 3.8e-194 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LHAPMBCL_01264 7.08e-186 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LHAPMBCL_01265 8.08e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
LHAPMBCL_01266 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LHAPMBCL_01267 1.62e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LHAPMBCL_01268 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LHAPMBCL_01269 5.79e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
LHAPMBCL_01270 2.41e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LHAPMBCL_01271 1.84e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LHAPMBCL_01272 2.88e-306 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LHAPMBCL_01273 6.05e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
LHAPMBCL_01274 5.94e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
LHAPMBCL_01275 2.43e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LHAPMBCL_01276 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LHAPMBCL_01277 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LHAPMBCL_01278 1.54e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LHAPMBCL_01279 4.97e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LHAPMBCL_01280 7.42e-125 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LHAPMBCL_01281 2.58e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LHAPMBCL_01282 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LHAPMBCL_01283 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LHAPMBCL_01284 5.49e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
LHAPMBCL_01285 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LHAPMBCL_01286 9.81e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LHAPMBCL_01287 4.36e-70 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LHAPMBCL_01288 5.72e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LHAPMBCL_01289 1.16e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LHAPMBCL_01290 7.29e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LHAPMBCL_01291 6.64e-139 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
LHAPMBCL_01292 5.45e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LHAPMBCL_01293 1.28e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
LHAPMBCL_01294 2.03e-66 - - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LHAPMBCL_01295 6.56e-121 - - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LHAPMBCL_01296 3.89e-242 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
LHAPMBCL_01297 2.89e-37 - 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
LHAPMBCL_01298 1.24e-189 - 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
LHAPMBCL_01299 8.14e-143 - - - S - - - Membrane
LHAPMBCL_01300 4.82e-156 - - - O - - - Zinc-dependent metalloprotease
LHAPMBCL_01301 9.38e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LHAPMBCL_01302 1.84e-203 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LHAPMBCL_01304 2.87e-218 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
LHAPMBCL_01305 6.82e-310 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LHAPMBCL_01306 4.31e-104 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LHAPMBCL_01307 3.03e-71 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LHAPMBCL_01308 3.02e-162 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LHAPMBCL_01309 1.51e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LHAPMBCL_01310 9.09e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
LHAPMBCL_01311 2.15e-121 ribB 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LHAPMBCL_01312 2.21e-121 ywlG - - S - - - Belongs to the UPF0340 family
LHAPMBCL_01313 8.97e-161 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
LHAPMBCL_01314 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
LHAPMBCL_01316 1.98e-278 - - - S ko:K07133 - ko00000 cog cog1373
LHAPMBCL_01317 8.32e-226 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
LHAPMBCL_01318 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
LHAPMBCL_01320 1.29e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
LHAPMBCL_01321 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHAPMBCL_01322 8.68e-316 yycH - - S - - - YycH protein
LHAPMBCL_01323 2.91e-192 yycI - - S - - - YycH protein
LHAPMBCL_01324 8.43e-195 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
LHAPMBCL_01325 9.07e-261 - - - - - - - -
LHAPMBCL_01326 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LHAPMBCL_01327 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LHAPMBCL_01328 4.22e-143 - - - K - - - Bacterial regulatory proteins, tetR family
LHAPMBCL_01329 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LHAPMBCL_01330 1.39e-101 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
LHAPMBCL_01331 1.8e-249 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
LHAPMBCL_01332 4.82e-84 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
LHAPMBCL_01333 9.35e-132 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
LHAPMBCL_01339 1.83e-148 dgk2 - - F - - - deoxynucleoside kinase
LHAPMBCL_01340 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
LHAPMBCL_01341 1.21e-06 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LHAPMBCL_01342 1.89e-151 - - - I - - - phosphatase
LHAPMBCL_01343 1.44e-104 - - - S - - - Threonine/Serine exporter, ThrE
LHAPMBCL_01344 9.53e-163 - - - S - - - Putative threonine/serine exporter
LHAPMBCL_01345 6e-41 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
LHAPMBCL_01346 2.22e-159 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
LHAPMBCL_01347 3.18e-209 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
LHAPMBCL_01348 7.03e-150 - - - S - - - membrane
LHAPMBCL_01349 1.11e-140 - - - S - - - VIT family
LHAPMBCL_01350 4.64e-106 - - - T - - - Belongs to the universal stress protein A family
LHAPMBCL_01351 6.59e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LHAPMBCL_01352 1.57e-194 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHAPMBCL_01353 7.44e-143 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LHAPMBCL_01354 8.58e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LHAPMBCL_01355 3.54e-276 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LHAPMBCL_01356 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LHAPMBCL_01357 1.52e-70 - - - - - - - -
LHAPMBCL_01358 1.08e-97 - - - K - - - MerR HTH family regulatory protein
LHAPMBCL_01359 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
LHAPMBCL_01360 9.06e-150 - - - S - - - Domain of unknown function (DUF4811)
LHAPMBCL_01361 3.05e-203 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LHAPMBCL_01363 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LHAPMBCL_01364 6.53e-133 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
LHAPMBCL_01365 2.44e-189 - - - I - - - Alpha beta
LHAPMBCL_01366 8.67e-21 - - - I - - - Alpha beta
LHAPMBCL_01367 1.09e-251 qacA - - EGP - - - Major Facilitator
LHAPMBCL_01368 1.83e-150 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
LHAPMBCL_01369 0.0 - - - S - - - Putative threonine/serine exporter
LHAPMBCL_01370 1.63e-201 - - - K - - - LysR family
LHAPMBCL_01371 2.07e-142 - - - I - - - Alpha/beta hydrolase family
LHAPMBCL_01372 9.53e-195 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
LHAPMBCL_01373 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
LHAPMBCL_01374 2.32e-204 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
LHAPMBCL_01375 2.56e-56 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
LHAPMBCL_01376 3.81e-187 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
LHAPMBCL_01377 2.43e-225 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
LHAPMBCL_01378 1.24e-157 citR - - K - - - sugar-binding domain protein
LHAPMBCL_01379 3.04e-216 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
LHAPMBCL_01380 2.1e-166 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LHAPMBCL_01381 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
LHAPMBCL_01382 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LHAPMBCL_01383 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
LHAPMBCL_01384 2.21e-198 mleR - - K - - - LysR family
LHAPMBCL_01385 1.17e-143 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LHAPMBCL_01386 2.61e-261 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
LHAPMBCL_01387 0.0 - - - L - - - PFAM plasmid pRiA4b ORF-3 family protein
LHAPMBCL_01388 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
LHAPMBCL_01391 6.92e-31 - - - - - - - -
LHAPMBCL_01392 1.1e-256 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
LHAPMBCL_01393 3.1e-96 - - - - - - - -
LHAPMBCL_01394 6.09e-277 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LHAPMBCL_01395 7.93e-178 - - - V - - - Beta-lactamase enzyme family
LHAPMBCL_01396 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
LHAPMBCL_01397 1.09e-275 - - - EGP - - - Transporter, major facilitator family protein
LHAPMBCL_01398 0.0 arcT - - E - - - Dipeptidase
LHAPMBCL_01399 0.0 arcD - - S - - - C4-dicarboxylate anaerobic carrier
LHAPMBCL_01400 2.83e-229 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
LHAPMBCL_01401 1.34e-178 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
LHAPMBCL_01402 3.75e-32 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
LHAPMBCL_01403 3.06e-216 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
LHAPMBCL_01404 1.92e-204 - - - EG - - - EamA-like transporter family
LHAPMBCL_01405 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LHAPMBCL_01406 1.98e-42 - - - S - - - Transglycosylase associated protein
LHAPMBCL_01407 1.85e-09 - - - S - - - CsbD-like
LHAPMBCL_01408 8.03e-231 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LHAPMBCL_01409 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
LHAPMBCL_01410 6.12e-123 - - - K - - - Transcriptional regulator (TetR family)
LHAPMBCL_01411 6.09e-53 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
LHAPMBCL_01412 1.98e-194 - - - - - - - -
LHAPMBCL_01413 1.77e-33 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
LHAPMBCL_01414 1.22e-106 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
LHAPMBCL_01415 1.17e-126 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
LHAPMBCL_01416 2.53e-97 - - - F - - - Nudix hydrolase
LHAPMBCL_01417 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
LHAPMBCL_01418 4.44e-292 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
LHAPMBCL_01419 2.16e-88 - - - - - - - -
LHAPMBCL_01420 2.86e-138 - - - - - - - -
LHAPMBCL_01421 3.46e-266 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHAPMBCL_01422 6.29e-183 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LHAPMBCL_01423 9.72e-185 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LHAPMBCL_01424 7.22e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LHAPMBCL_01425 6.63e-203 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
LHAPMBCL_01426 1.42e-222 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LHAPMBCL_01427 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
LHAPMBCL_01428 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
LHAPMBCL_01429 1.57e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LHAPMBCL_01430 3.01e-107 - - - - - - - -
LHAPMBCL_01431 1.78e-204 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
LHAPMBCL_01432 4.18e-15 - - - K - - - Cro/C1-type HTH DNA-binding domain
LHAPMBCL_01433 1.25e-55 - - - - - - - -
LHAPMBCL_01434 1.1e-199 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
LHAPMBCL_01436 2.18e-70 - - - L - - - Resolvase, N terminal domain
LHAPMBCL_01437 2.83e-180 kdsA 2.5.1.55 - H ko:K01627 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the KdsA family
LHAPMBCL_01438 1.22e-180 kdsD 5.3.1.13 - M ko:K06041 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 sugar phosphate isomerase involved in capsule formation
LHAPMBCL_01439 4.47e-10 - - - L - - - Transposase and inactivated derivatives IS30 family
LHAPMBCL_01440 3.69e-54 - - - - - - - -
LHAPMBCL_01441 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
LHAPMBCL_01442 5.5e-162 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
LHAPMBCL_01443 6.65e-104 usp5 - - T - - - universal stress protein
LHAPMBCL_01444 8.05e-106 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
LHAPMBCL_01445 2.49e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LHAPMBCL_01446 4.2e-103 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
LHAPMBCL_01447 1.62e-230 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LHAPMBCL_01448 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
LHAPMBCL_01449 3.46e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LHAPMBCL_01450 1.38e-227 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
LHAPMBCL_01451 1.57e-186 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
LHAPMBCL_01452 5.55e-121 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
LHAPMBCL_01453 8.25e-47 - - - - - - - -
LHAPMBCL_01454 6.45e-111 - - - S - - - Protein conserved in bacteria
LHAPMBCL_01455 2.38e-229 - - - - - - - -
LHAPMBCL_01456 1.98e-202 - - - - - - - -
LHAPMBCL_01457 0.0 - 2.4.1.5 GH13 G ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
LHAPMBCL_01458 1.63e-163 - - - L - - - PFAM transposase, IS4 family protein
LHAPMBCL_01459 2.27e-253 glpT - - G ko:K02445 - ko00000,ko02000 Major Facilitator Superfamily
LHAPMBCL_01460 7.12e-76 - - - L - - - Resolvase, N terminal domain
LHAPMBCL_01461 7.85e-84 yuxO - - Q - - - Thioesterase superfamily
LHAPMBCL_01462 1.64e-199 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LHAPMBCL_01463 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LHAPMBCL_01464 9.85e-131 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
LHAPMBCL_01465 1.62e-210 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
LHAPMBCL_01466 4.89e-43 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
LHAPMBCL_01467 5.43e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
LHAPMBCL_01468 1.03e-299 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
LHAPMBCL_01469 1.68e-294 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LHAPMBCL_01470 9.11e-106 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
LHAPMBCL_01471 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
LHAPMBCL_01472 1.18e-76 - - - S - - - Iron-sulfur cluster assembly protein
LHAPMBCL_01473 5.26e-203 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
LHAPMBCL_01474 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
LHAPMBCL_01475 1.23e-276 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LHAPMBCL_01476 8.91e-224 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LHAPMBCL_01477 8.01e-97 - - - O - - - OsmC-like protein
LHAPMBCL_01478 9.85e-154 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LHAPMBCL_01479 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
LHAPMBCL_01480 4.56e-154 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
LHAPMBCL_01481 9.77e-95 - - - S - - - Protein of unknown function (DUF1275)
LHAPMBCL_01482 2.26e-21 - - - S - - - Protein of unknown function (DUF1275)
LHAPMBCL_01483 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LHAPMBCL_01484 1.46e-199 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LHAPMBCL_01485 1.9e-125 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LHAPMBCL_01486 2.82e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LHAPMBCL_01487 9.89e-301 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
LHAPMBCL_01488 7.06e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
LHAPMBCL_01489 1.07e-110 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LHAPMBCL_01490 1.82e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
LHAPMBCL_01491 5.46e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LHAPMBCL_01493 1.22e-17 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
LHAPMBCL_01494 6.43e-251 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
LHAPMBCL_01495 2.58e-113 - - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
LHAPMBCL_01496 1.09e-196 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
LHAPMBCL_01497 1.05e-95 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
LHAPMBCL_01498 1.15e-144 repA - - S - - - Replication initiator protein A
LHAPMBCL_01499 5.31e-143 nanA 4.1.3.3 - E ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LHAPMBCL_01500 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
LHAPMBCL_01502 5.08e-164 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LHAPMBCL_01503 4.56e-267 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
LHAPMBCL_01504 2.07e-147 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LHAPMBCL_01505 1.1e-46 ynzC - - S - - - UPF0291 protein
LHAPMBCL_01506 1.72e-39 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
LHAPMBCL_01507 1.52e-151 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
LHAPMBCL_01508 1.98e-180 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
LHAPMBCL_01509 5.59e-64 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
LHAPMBCL_01510 7.7e-229 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LHAPMBCL_01511 3.54e-184 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
LHAPMBCL_01512 2.58e-196 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LHAPMBCL_01513 3.66e-166 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
LHAPMBCL_01514 8.54e-123 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LHAPMBCL_01515 2.13e-181 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LHAPMBCL_01516 2.03e-178 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
LHAPMBCL_01517 6.65e-298 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
LHAPMBCL_01518 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LHAPMBCL_01519 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LHAPMBCL_01520 2.59e-107 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
LHAPMBCL_01521 2.78e-273 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
LHAPMBCL_01522 5.93e-60 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
LHAPMBCL_01523 1.96e-65 ylxQ - - J - - - ribosomal protein
LHAPMBCL_01524 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LHAPMBCL_01525 1.38e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LHAPMBCL_01526 1.16e-213 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LHAPMBCL_01527 6.32e-225 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
LHAPMBCL_01528 3.09e-85 - - - - - - - -
LHAPMBCL_01529 3.23e-247 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LHAPMBCL_01530 2.71e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LHAPMBCL_01531 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
LHAPMBCL_01532 1.31e-265 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LHAPMBCL_01533 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LHAPMBCL_01534 3.67e-226 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
LHAPMBCL_01535 3.65e-291 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LHAPMBCL_01536 9.75e-184 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
LHAPMBCL_01537 1.01e-109 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
LHAPMBCL_01538 2.06e-102 - - - Q - - - Methyltransferase
LHAPMBCL_01539 4.64e-151 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
LHAPMBCL_01540 7.89e-304 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
LHAPMBCL_01541 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
LHAPMBCL_01542 4.28e-176 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
LHAPMBCL_01543 5.36e-270 - - - G - - - Glycosyl hydrolases family 8
LHAPMBCL_01544 1.83e-296 - - - M - - - Glycosyl transferase
LHAPMBCL_01545 1.94e-84 - - - - - - - -
LHAPMBCL_01546 6.77e-166 yebC - - K - - - Transcriptional regulatory protein
LHAPMBCL_01547 4.1e-172 - - - - - - - -
LHAPMBCL_01548 2.21e-231 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
LHAPMBCL_01549 4.72e-264 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
LHAPMBCL_01550 3.04e-74 - - - - - - - -
LHAPMBCL_01551 3.61e-70 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LHAPMBCL_01552 5.96e-186 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
LHAPMBCL_01553 2.71e-196 - - - S - - - haloacid dehalogenase-like hydrolase
LHAPMBCL_01554 1.72e-98 ykuL - - S - - - (CBS) domain
LHAPMBCL_01555 7.84e-119 - - - S ko:K07095 - ko00000 Phosphoesterase
LHAPMBCL_01556 5.53e-130 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LHAPMBCL_01557 1.87e-177 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
LHAPMBCL_01558 5.16e-72 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LHAPMBCL_01559 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
LHAPMBCL_01560 3.39e-157 - - - S - - - SNARE associated Golgi protein
LHAPMBCL_01561 9.36e-294 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
LHAPMBCL_01562 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LHAPMBCL_01564 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
LHAPMBCL_01565 5.47e-199 endA - - V ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
LHAPMBCL_01566 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LHAPMBCL_01567 9.73e-55 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
LHAPMBCL_01568 6.49e-94 - - - S - - - Protein of unknown function (DUF3290)
LHAPMBCL_01569 1.7e-148 - - - S - - - Protein of unknown function (DUF421)
LHAPMBCL_01570 1.47e-209 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LHAPMBCL_01571 1.15e-25 - - - - - - - -
LHAPMBCL_01572 1.14e-116 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
LHAPMBCL_01573 9.68e-193 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
LHAPMBCL_01574 1.1e-57 yrvD - - S - - - Pfam:DUF1049
LHAPMBCL_01576 2.92e-14 - - - S - - - Phage derived protein Gp49-like (DUF891)
LHAPMBCL_01577 7.69e-06 - - - K - - - Helix-turn-helix XRE-family like proteins
LHAPMBCL_01578 1.7e-06 - - - K - - - Helix-turn-helix XRE-family like proteins
LHAPMBCL_01579 2.51e-209 - - - I - - - alpha/beta hydrolase fold
LHAPMBCL_01580 1.04e-103 - - - S - - - Short repeat of unknown function (DUF308)
LHAPMBCL_01581 8.21e-97 - - - S - - - Psort location Cytoplasmic, score
LHAPMBCL_01582 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
LHAPMBCL_01583 6.32e-99 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LHAPMBCL_01584 1.5e-195 yeaE - - S - - - Aldo keto
LHAPMBCL_01585 1.8e-306 - 1.3.1.1 - C ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
LHAPMBCL_01586 8.64e-253 - 1.3.1.1 - E ko:K17722 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
LHAPMBCL_01587 4.89e-191 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
LHAPMBCL_01588 5.1e-134 - - - M - - - LysM domain protein
LHAPMBCL_01589 0.0 - - - EP - - - Psort location Cytoplasmic, score
LHAPMBCL_01590 9.91e-06 - - - L - - - GIY-YIG catalytic domain
LHAPMBCL_01595 7.4e-114 - - - S ko:K06919 - ko00000 DNA primase
LHAPMBCL_01599 2.24e-41 - - - L ko:K07451 - ko00000,ko01000,ko02048 Phage-associated protein
LHAPMBCL_01600 1.05e-32 terS - - L - - - Phage terminase, small subunit
LHAPMBCL_01601 3.54e-251 terL - - S - - - overlaps another CDS with the same product name
LHAPMBCL_01602 4.15e-173 - - - S - - - Phage portal protein
LHAPMBCL_01603 1.59e-233 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
LHAPMBCL_01604 1.64e-21 - - - S - - - Phage gp6-like head-tail connector protein
LHAPMBCL_01606 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
LHAPMBCL_01607 5.88e-233 galR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
LHAPMBCL_01608 1.73e-215 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
LHAPMBCL_01609 1.62e-227 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LHAPMBCL_01610 5.11e-160 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
LHAPMBCL_01611 3.69e-87 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
LHAPMBCL_01612 7.33e-163 lytT - - K ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator receiver
LHAPMBCL_01613 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 LytS YhcK-type transmembrane receptor domain protein
LHAPMBCL_01614 3.12e-191 - - - O - - - Band 7 protein
LHAPMBCL_01615 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
LHAPMBCL_01616 1.1e-196 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
LHAPMBCL_01617 1.43e-51 - - - S - - - Cytochrome B5
LHAPMBCL_01618 1.84e-103 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
LHAPMBCL_01619 2.74e-94 - - - S - - - Bacterial membrane protein, YfhO
LHAPMBCL_01620 3.88e-12 - - - - - - - -
LHAPMBCL_01621 5.01e-112 - - - S - - - Glycosyltransferase like family
LHAPMBCL_01622 1.06e-109 - - - M - - - Domain of unknown function (DUF4422)
LHAPMBCL_01623 2.19e-51 - - - M - - - biosynthesis protein
LHAPMBCL_01624 2.5e-115 cps3F - - - - - - -
LHAPMBCL_01625 2.18e-129 - - - M - - - Glycosyltransferase like family 2
LHAPMBCL_01626 3.64e-140 - - - S - - - Glycosyltransferase like family 2
LHAPMBCL_01627 4.91e-93 - - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 2
LHAPMBCL_01628 4.63e-270 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
LHAPMBCL_01629 2.9e-277 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
LHAPMBCL_01630 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
LHAPMBCL_01631 5.5e-99 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
LHAPMBCL_01632 1.99e-72 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
LHAPMBCL_01633 0.0 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Ami_3
LHAPMBCL_01634 3.57e-236 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LHAPMBCL_01635 3.59e-304 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
LHAPMBCL_01636 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
LHAPMBCL_01637 1.49e-110 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
LHAPMBCL_01638 6.25e-220 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LHAPMBCL_01639 5.03e-232 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
LHAPMBCL_01640 3.66e-108 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LHAPMBCL_01641 1.66e-77 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
LHAPMBCL_01642 2.66e-219 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LHAPMBCL_01643 4.15e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
LHAPMBCL_01644 2.5e-233 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
LHAPMBCL_01645 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
LHAPMBCL_01646 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LHAPMBCL_01647 1.47e-265 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LHAPMBCL_01648 1.19e-278 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LHAPMBCL_01649 1.44e-165 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
LHAPMBCL_01650 2.07e-198 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LHAPMBCL_01651 3.71e-300 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
LHAPMBCL_01652 7.94e-42 - - - S - - - Protein of unknown function (DUF2929)
LHAPMBCL_01653 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
LHAPMBCL_01654 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
LHAPMBCL_01655 7.61e-215 yitL - - S ko:K00243 - ko00000 S1 domain
LHAPMBCL_01656 4.06e-212 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
LHAPMBCL_01657 3.67e-86 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LHAPMBCL_01658 3.37e-178 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LHAPMBCL_01659 2.72e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LHAPMBCL_01660 1.37e-162 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LHAPMBCL_01661 1.08e-132 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LHAPMBCL_01662 1.79e-244 - - - S - - - Helix-turn-helix domain
LHAPMBCL_01663 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
LHAPMBCL_01664 1.31e-55 - - - M - - - Lysin motif
LHAPMBCL_01665 1.55e-152 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
LHAPMBCL_01666 1.49e-274 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
LHAPMBCL_01667 9.51e-317 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
LHAPMBCL_01668 1.6e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LHAPMBCL_01669 5.49e-300 XK27_05225 - - S - - - Tetratricopeptide repeat protein
LHAPMBCL_01670 1.16e-285 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LHAPMBCL_01671 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
LHAPMBCL_01672 7e-245 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LHAPMBCL_01673 1.09e-115 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LHAPMBCL_01674 6.1e-143 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
LHAPMBCL_01675 6.38e-196 WQ51_01275 - - S - - - EDD domain protein, DegV family
LHAPMBCL_01676 2.45e-216 - - - E - - - lipolytic protein G-D-S-L family
LHAPMBCL_01677 5.75e-141 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
LHAPMBCL_01678 1.33e-47 yozE - - S - - - Belongs to the UPF0346 family
LHAPMBCL_01679 2.08e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LHAPMBCL_01680 1.01e-180 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LHAPMBCL_01681 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LHAPMBCL_01682 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
LHAPMBCL_01683 6.36e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
LHAPMBCL_01684 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LHAPMBCL_01685 1.86e-114 - - - - - - - -
LHAPMBCL_01686 3.96e-49 - - - - - - - -
LHAPMBCL_01687 1.17e-131 - - - K - - - DNA-templated transcription, initiation
LHAPMBCL_01688 1.67e-38 - - - - - - - -
LHAPMBCL_01689 2.98e-78 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
LHAPMBCL_01690 7.26e-267 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
LHAPMBCL_01691 1.7e-118 - - - - - - - -
LHAPMBCL_01692 1.27e-86 - - - K - - - Transcriptional regulator, HxlR family
LHAPMBCL_01693 6.01e-223 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LHAPMBCL_01694 8.47e-186 epsB - - M - - - biosynthesis protein
LHAPMBCL_01695 2.57e-151 ywqD - - D - - - Capsular exopolysaccharide family
LHAPMBCL_01696 4.19e-133 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
LHAPMBCL_01697 7.85e-96 - - - M - - - Oligosaccharide biosynthesis protein Alg14 like
LHAPMBCL_01698 4.28e-65 - - - S - - - Glycosyltransferase family 28 C-terminal domain
LHAPMBCL_01699 1.37e-75 - - - M - - - Glycosyltransferase like family 2
LHAPMBCL_01700 1.53e-90 - - - M - - - transferase activity, transferring glycosyl groups
LHAPMBCL_01701 1.12e-24 - - - - - - - -
LHAPMBCL_01704 1.02e-198 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LHAPMBCL_01705 1.04e-245 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LHAPMBCL_01706 2.14e-139 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LHAPMBCL_01707 8.7e-279 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
LHAPMBCL_01708 2.8e-143 eriC - - P ko:K03281 - ko00000 chloride
LHAPMBCL_01709 9.12e-139 eriC - - P ko:K03281 - ko00000 chloride
LHAPMBCL_01710 1.05e-101 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
LHAPMBCL_01711 6.56e-137 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
LHAPMBCL_01712 6.85e-179 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LHAPMBCL_01713 4.74e-139 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LHAPMBCL_01714 5.93e-206 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
LHAPMBCL_01715 3.31e-98 ywnA - - K - - - Transcriptional regulator
LHAPMBCL_01716 3.78e-157 - - - GM - - - NAD(P)H-binding
LHAPMBCL_01717 7.65e-12 - - - - - - - -
LHAPMBCL_01718 1.04e-268 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Metalloenzyme superfamily
LHAPMBCL_01719 0.0 cadA - - P - - - P-type ATPase
LHAPMBCL_01720 1.74e-166 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
LHAPMBCL_01721 2.04e-160 - - - - - - - -
LHAPMBCL_01722 1.85e-69 - - - S - - - Sugar efflux transporter for intercellular exchange
LHAPMBCL_01723 3.67e-311 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
LHAPMBCL_01725 0.0 - - - L - - - Helicase C-terminal domain protein
LHAPMBCL_01726 3.45e-105 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 PAP2 superfamily
LHAPMBCL_01727 7.38e-225 ydhF - - S - - - Aldo keto reductase
LHAPMBCL_01728 1.28e-274 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
LHAPMBCL_01729 4.95e-63 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
LHAPMBCL_01730 7.79e-281 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
LHAPMBCL_01731 1.09e-42 - - - S - - - Protein of unknown function (DUF2969)
LHAPMBCL_01732 1.05e-226 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
LHAPMBCL_01733 8.24e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LHAPMBCL_01734 1.76e-45 ywzB - - S - - - Protein of unknown function (DUF1146)
LHAPMBCL_01735 3.52e-161 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
LHAPMBCL_01736 9.02e-177 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LHAPMBCL_01737 5.44e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
LHAPMBCL_01738 2.17e-192 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
LHAPMBCL_01739 8.59e-161 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
LHAPMBCL_01740 1.46e-133 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
LHAPMBCL_01741 5.23e-171 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHAPMBCL_01742 9.97e-185 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
LHAPMBCL_01743 1.61e-229 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
LHAPMBCL_01744 1.07e-205 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
LHAPMBCL_01745 8.11e-145 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LHAPMBCL_01746 2.02e-162 ureF - - O ko:K03188 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
LHAPMBCL_01747 3.08e-102 ureE - - O ko:K03187 - ko00000 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
LHAPMBCL_01748 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Amidohydrolase family
LHAPMBCL_01749 7.81e-82 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Urease beta subunit
LHAPMBCL_01750 1.66e-55 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Urease, gamma subunit
LHAPMBCL_01751 8.47e-127 - - - S - - - AmiS/UreI family transporter
LHAPMBCL_01752 2.68e-216 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
LHAPMBCL_01753 2.2e-39 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
LHAPMBCL_01755 1.41e-239 - - - - - - - -
LHAPMBCL_01756 2.71e-125 - - - K - - - acetyltransferase
LHAPMBCL_01757 1.57e-123 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LHAPMBCL_01758 1.98e-203 - - - K - - - LysR substrate binding domain
LHAPMBCL_01759 4.34e-261 - 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
LHAPMBCL_01760 9.99e-83 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LHAPMBCL_01761 3.61e-34 - - - - - - - -
LHAPMBCL_01762 6.59e-124 - - - - - - - -
LHAPMBCL_01763 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
LHAPMBCL_01764 4.12e-234 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
LHAPMBCL_01765 5.67e-297 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
LHAPMBCL_01766 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
LHAPMBCL_01767 4.86e-124 - - - K - - - Acetyltransferase (GNAT) domain
LHAPMBCL_01768 3.8e-63 - - - - - - - -
LHAPMBCL_01769 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
LHAPMBCL_01770 1.26e-60 - - - - - - - -
LHAPMBCL_01771 3.31e-97 - - - S - - - Protein of unknown function (DUF805)
LHAPMBCL_01772 4.26e-178 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
LHAPMBCL_01773 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
LHAPMBCL_01774 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
LHAPMBCL_01775 1.93e-161 - - - L - - - Type I restriction modification DNA specificity domain
LHAPMBCL_01776 9.34e-225 - - - L - - - Belongs to the 'phage' integrase family
LHAPMBCL_01777 1.54e-79 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
LHAPMBCL_01778 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LHAPMBCL_01779 3.71e-109 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
LHAPMBCL_01780 2.61e-190 ylmH - - S - - - S4 domain protein
LHAPMBCL_01781 3.2e-54 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
LHAPMBCL_01782 5.27e-91 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LHAPMBCL_01783 6.52e-289 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LHAPMBCL_01784 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LHAPMBCL_01785 6.12e-195 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LHAPMBCL_01786 8.41e-260 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LHAPMBCL_01787 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LHAPMBCL_01788 3.83e-230 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LHAPMBCL_01789 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LHAPMBCL_01790 9.94e-73 ftsL - - D - - - Cell division protein FtsL
LHAPMBCL_01791 8.92e-222 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LHAPMBCL_01792 4.29e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
LHAPMBCL_01793 1.65e-77 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LHAPMBCL_01795 5.36e-27 - - - - ko:K18829 - ko00000,ko02048 -
LHAPMBCL_01797 0.0 snf - - KL - - - domain protein
LHAPMBCL_01798 1.75e-182 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
LHAPMBCL_01799 4.4e-119 - - - M - - - Glycosyl hydrolases family 25
LHAPMBCL_01800 4.55e-265 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LHAPMBCL_01801 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
LHAPMBCL_01802 4.83e-134 - - - L - - - nuclease
LHAPMBCL_01803 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LHAPMBCL_01804 5.24e-92 - - - - - - - -
LHAPMBCL_01805 2.77e-133 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
LHAPMBCL_01806 6.82e-159 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LHAPMBCL_01807 0.0 - - - - - - - -
LHAPMBCL_01808 1.08e-189 - - - - - - - -
LHAPMBCL_01809 3.47e-240 - - - - - - - -
LHAPMBCL_01811 1.72e-305 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LHAPMBCL_01812 2.69e-234 - - - - - - - -
LHAPMBCL_01813 5.27e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LHAPMBCL_01814 9.62e-309 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
LHAPMBCL_01815 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
LHAPMBCL_01816 1.37e-134 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LHAPMBCL_01817 2.01e-243 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
LHAPMBCL_01818 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LHAPMBCL_01819 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LHAPMBCL_01820 3.84e-161 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LHAPMBCL_01821 6.39e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LHAPMBCL_01822 4.82e-166 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
LHAPMBCL_01823 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LHAPMBCL_01824 5.14e-268 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LHAPMBCL_01825 8.95e-110 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LHAPMBCL_01826 2.3e-168 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
LHAPMBCL_01827 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
LHAPMBCL_01828 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
LHAPMBCL_01829 3.55e-221 ydbI - - K - - - AI-2E family transporter
LHAPMBCL_01830 2.01e-289 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
LHAPMBCL_01831 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LHAPMBCL_01832 4.1e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LHAPMBCL_01833 9.07e-300 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
LHAPMBCL_01834 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LHAPMBCL_01835 2.63e-08 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
LHAPMBCL_01836 7.38e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LHAPMBCL_01837 8.52e-267 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LHAPMBCL_01838 1.3e-82 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
LHAPMBCL_01839 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
LHAPMBCL_01840 6.48e-308 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
LHAPMBCL_01841 4.85e-187 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
LHAPMBCL_01843 3.71e-199 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
LHAPMBCL_01844 9.21e-244 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LHAPMBCL_01845 9.27e-220 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
LHAPMBCL_01846 3.71e-205 - - - EG - - - EamA-like transporter family
LHAPMBCL_01847 8.21e-133 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
LHAPMBCL_01848 7.61e-81 - - - S - - - Cupredoxin-like domain
LHAPMBCL_01849 3.66e-64 - - - S - - - Cupredoxin-like domain
LHAPMBCL_01850 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
LHAPMBCL_01851 1.1e-113 - - - - - - - -
LHAPMBCL_01853 2.49e-73 - - - - - - - -
LHAPMBCL_01854 1.55e-45 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
LHAPMBCL_01856 5.64e-119 - - - - - - - -
LHAPMBCL_01857 0.0 - - - M - - - domain protein
LHAPMBCL_01858 2.02e-59 - - - - - - - -
LHAPMBCL_01859 6.78e-227 ampC - - V - - - Beta-lactamase
LHAPMBCL_01860 4.19e-303 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
LHAPMBCL_01861 5.07e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
LHAPMBCL_01862 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
LHAPMBCL_01863 1.14e-296 potE - - U ko:K03756,ko:K03758 - ko00000,ko02000 Amino acid permease
LHAPMBCL_01864 4e-172 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
LHAPMBCL_01865 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
LHAPMBCL_01866 6.8e-140 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
LHAPMBCL_01867 1.73e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LHAPMBCL_01868 6.47e-209 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LHAPMBCL_01869 4.43e-250 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LHAPMBCL_01870 1.74e-291 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LHAPMBCL_01871 5.49e-149 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LHAPMBCL_01872 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LHAPMBCL_01873 1.69e-241 yibE - - S - - - overlaps another CDS with the same product name
LHAPMBCL_01874 4.71e-166 yibF - - S - - - overlaps another CDS with the same product name
LHAPMBCL_01875 4.63e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
LHAPMBCL_01876 4.63e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
LHAPMBCL_01877 1.26e-29 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LHAPMBCL_01878 2.42e-92 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LHAPMBCL_01879 1.14e-119 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LHAPMBCL_01880 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LHAPMBCL_01881 1.3e-212 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LHAPMBCL_01882 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LHAPMBCL_01883 1.22e-112 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
LHAPMBCL_01884 1.48e-246 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LHAPMBCL_01885 7.95e-272 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
LHAPMBCL_01886 5.73e-216 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
LHAPMBCL_01887 1.36e-215 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
LHAPMBCL_01888 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
LHAPMBCL_01889 2.61e-112 ypmB - - S - - - Protein conserved in bacteria
LHAPMBCL_01890 3.24e-157 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
LHAPMBCL_01891 2.42e-208 - - - EG - - - EamA-like transporter family
LHAPMBCL_01892 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
LHAPMBCL_01893 7.01e-153 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LHAPMBCL_01894 7.96e-129 ypsA - - S - - - Belongs to the UPF0398 family
LHAPMBCL_01895 6.82e-74 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LHAPMBCL_01896 1.18e-108 - - - F ko:K03647 - ko00000 Belongs to the NrdI family
LHAPMBCL_01897 5.69e-281 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
LHAPMBCL_01898 5.19e-90 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
LHAPMBCL_01899 2.58e-85 esbA - - S - - - Family of unknown function (DUF5322)
LHAPMBCL_01900 7.28e-96 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LHAPMBCL_01901 5.85e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LHAPMBCL_01902 7.52e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
LHAPMBCL_01903 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
LHAPMBCL_01904 0.0 FbpA - - K - - - Fibronectin-binding protein
LHAPMBCL_01905 9.88e-206 - - - S - - - EDD domain protein, DegV family
LHAPMBCL_01906 2.62e-124 - - - - - - - -
LHAPMBCL_01908 1.71e-264 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LHAPMBCL_01909 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LHAPMBCL_01910 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
LHAPMBCL_01911 1.39e-76 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LHAPMBCL_01912 2.96e-172 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LHAPMBCL_01913 5.14e-169 jag - - S ko:K06346 - ko00000 R3H domain protein
LHAPMBCL_01914 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LHAPMBCL_01915 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LHAPMBCL_01916 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LHAPMBCL_01917 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LHAPMBCL_01918 4.97e-311 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
LHAPMBCL_01919 3.92e-38 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
LHAPMBCL_01920 1.47e-209 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LHAPMBCL_01921 9.83e-298 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LHAPMBCL_01922 9.43e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
LHAPMBCL_01923 3.89e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LHAPMBCL_01924 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LHAPMBCL_01925 6.44e-68 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LHAPMBCL_01926 6.53e-89 ywiB - - S - - - Domain of unknown function (DUF1934)
LHAPMBCL_01927 3.16e-193 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
LHAPMBCL_01928 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
LHAPMBCL_01929 2.58e-187 yidA - - S - - - hydrolase
LHAPMBCL_01930 1.07e-150 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
LHAPMBCL_01931 3.26e-64 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
LHAPMBCL_01932 7.94e-101 - - - - - - - -
LHAPMBCL_01933 3.53e-229 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LHAPMBCL_01934 1.37e-315 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LHAPMBCL_01935 2.09e-190 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
LHAPMBCL_01936 2.49e-165 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
LHAPMBCL_01937 4.85e-158 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LHAPMBCL_01938 1.3e-211 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LHAPMBCL_01939 1.41e-205 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LHAPMBCL_01940 2.74e-50 veg - - S - - - Biofilm formation stimulator VEG
LHAPMBCL_01941 5.93e-205 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LHAPMBCL_01942 6.03e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LHAPMBCL_01943 2.42e-196 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
LHAPMBCL_01944 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LHAPMBCL_01945 2.25e-206 yunF - - F - - - Protein of unknown function DUF72
LHAPMBCL_01947 4.85e-167 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
LHAPMBCL_01948 3.51e-224 - - - - - - - -
LHAPMBCL_01949 2.47e-291 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
LHAPMBCL_01950 2.53e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
LHAPMBCL_01951 3.2e-242 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LHAPMBCL_01952 6.41e-236 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
LHAPMBCL_01953 7.04e-107 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
LHAPMBCL_01954 0.0 - - - L - - - DNA helicase
LHAPMBCL_01955 2.13e-258 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LHAPMBCL_01957 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LHAPMBCL_01958 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
LHAPMBCL_01959 3.3e-151 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LHAPMBCL_01960 1.57e-56 - 1.3.5.4 - S ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN binding
LHAPMBCL_01961 2.41e-280 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
LHAPMBCL_01962 1.47e-216 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)