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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MHEPLEGL_00001	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
MHEPLEGL_00002	2.59e-241	flp	-	-	V	-	-	-	Beta-lactamase
MHEPLEGL_00003	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MHEPLEGL_00004	6.28e-59	-	-	-	-	-	-	-	-
MHEPLEGL_00005	7.54e-174	-	-	-	-	-	-	-	-
MHEPLEGL_00006	2.76e-115	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MHEPLEGL_00007	7.5e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MHEPLEGL_00008	7.65e-101	-	-	-	K	-	-	-	LytTr DNA-binding domain
MHEPLEGL_00009	1.42e-57	-	-	-	-	-	-	-	-
MHEPLEGL_00010	1.35e-161	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
MHEPLEGL_00011	8.76e-75	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MHEPLEGL_00012	3.41e-257	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
MHEPLEGL_00013	2.92e-314	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MHEPLEGL_00014	1.18e-254	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
MHEPLEGL_00015	2.7e-126	-	3.6.1.67	-	F	ko:K19965	ko00790,map00790	ko00000,ko00001,ko00002,ko01000	NUDIX domain
MHEPLEGL_00016	1.16e-97	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	N-formylglutamate amidohydrolase
MHEPLEGL_00017	2.03e-34	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
MHEPLEGL_00018	2.09e-91	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
MHEPLEGL_00019	1.32e-144	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
MHEPLEGL_00020	1.39e-121	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
MHEPLEGL_00021	4.83e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MHEPLEGL_00022	3.07e-206	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MHEPLEGL_00023	1.31e-71	-	-	-	L	-	-	-	Helix-turn-helix domain
MHEPLEGL_00024	8.28e-251	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MHEPLEGL_00025	9.15e-113	dpnM	2.1.1.72	-	H	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	Site-specific DNA-methyltransferase (adenine-specific)
MHEPLEGL_00027	1.36e-151	-	-	-	L	-	-	-	Integrase
MHEPLEGL_00029	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
MHEPLEGL_00030	1.07e-120	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MHEPLEGL_00031	1.23e-63	-	-	-	S	-	-	-	Alpha beta hydrolase
MHEPLEGL_00032	1.93e-16	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
MHEPLEGL_00033	6.36e-49	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
MHEPLEGL_00034	6.64e-184	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
MHEPLEGL_00035	6.75e-138	-	-	-	K	ko:K09705	-	ko00000	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MHEPLEGL_00036	4.08e-123	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MHEPLEGL_00037	3.99e-196	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
MHEPLEGL_00038	1.25e-119	-	-	-	K	-	-	-	acetyltransferase
MHEPLEGL_00039	1.7e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MHEPLEGL_00040	1.76e-36	-	-	-	-	-	-	-	-
MHEPLEGL_00041	3.14e-101	snf	-	-	KL	-	-	-	domain protein
MHEPLEGL_00042	1.02e-45	snf	-	-	KL	-	-	-	domain protein
MHEPLEGL_00043	2.82e-163	snf	-	-	KL	-	-	-	domain protein
MHEPLEGL_00044	3.55e-139	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MHEPLEGL_00045	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHEPLEGL_00046	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHEPLEGL_00047	2.01e-216	-	-	-	K	-	-	-	Transcriptional regulator
MHEPLEGL_00048	6.05e-221	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
MHEPLEGL_00049	2.19e-142	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MHEPLEGL_00050	7.76e-74	-	-	-	K	-	-	-	Helix-turn-helix domain
MHEPLEGL_00051	7.19e-137	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
MHEPLEGL_00052	8.71e-45	-	-	-	S	-	-	-	Transglycosylase associated protein
MHEPLEGL_00053	8.63e-31	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MHEPLEGL_00054	2.42e-59	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MHEPLEGL_00055	8.2e-56	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MHEPLEGL_00056	2.25e-34	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MHEPLEGL_00057	3.27e-71	-	-	-	-	-	-	-	-
MHEPLEGL_00058	1.35e-140	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
MHEPLEGL_00059	2.88e-116	flaR	-	-	F	-	-	-	topology modulation protein
MHEPLEGL_00060	2.61e-95	-	-	-	-	-	-	-	-
MHEPLEGL_00061	2.33e-261	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
MHEPLEGL_00062	2.16e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
MHEPLEGL_00063	5.69e-86	-	-	-	-	-	-	-	-
MHEPLEGL_00064	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
MHEPLEGL_00065	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MHEPLEGL_00066	1.23e-256	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MHEPLEGL_00067	8.92e-219	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MHEPLEGL_00068	1.1e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MHEPLEGL_00069	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
MHEPLEGL_00070	1.05e-49	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MHEPLEGL_00071	1.29e-108	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MHEPLEGL_00072	5.39e-14	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MHEPLEGL_00073	3.54e-279	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MHEPLEGL_00074	1.29e-91	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MHEPLEGL_00075	3.95e-138	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MHEPLEGL_00076	9.14e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MHEPLEGL_00077	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
MHEPLEGL_00078	1.46e-146	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MHEPLEGL_00079	5.68e-148	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
MHEPLEGL_00080	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
MHEPLEGL_00081	2.46e-116	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
MHEPLEGL_00082	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MHEPLEGL_00083	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MHEPLEGL_00084	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MHEPLEGL_00085	5.35e-215	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
MHEPLEGL_00086	1.06e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
MHEPLEGL_00087	4.69e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
MHEPLEGL_00088	1.52e-239	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MHEPLEGL_00089	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
MHEPLEGL_00090	1.75e-228	-	-	-	-	-	-	-	-
MHEPLEGL_00091	1.83e-180	-	-	-	-	-	-	-	-
MHEPLEGL_00092	1.04e-133	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MHEPLEGL_00093	7.83e-38	-	-	-	-	-	-	-	-
MHEPLEGL_00094	9.06e-137	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MHEPLEGL_00095	2.19e-41	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MHEPLEGL_00096	3.03e-13	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MHEPLEGL_00097	6.33e-61	-	-	-	-	-	-	-	-
MHEPLEGL_00098	1.13e-289	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MHEPLEGL_00099	8.59e-224	-	-	-	-	-	-	-	-
MHEPLEGL_00100	4.12e-79	lysM	-	-	M	-	-	-	LysM domain
MHEPLEGL_00101	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
MHEPLEGL_00102	4.21e-132	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
MHEPLEGL_00103	1.99e-25	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
MHEPLEGL_00104	2.74e-66	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
MHEPLEGL_00105	2.33e-156	-	-	-	-	-	-	-	-
MHEPLEGL_00106	1.06e-185	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
MHEPLEGL_00107	7.18e-183	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
MHEPLEGL_00108	1.21e-144	-	-	-	G	-	-	-	phosphoglycerate mutase
MHEPLEGL_00109	8.42e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MHEPLEGL_00110	1.59e-228	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MHEPLEGL_00111	3.4e-154	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHEPLEGL_00112	1.17e-280	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MHEPLEGL_00113	1.16e-51	-	-	-	-	-	-	-	-
MHEPLEGL_00114	5.2e-144	-	-	-	K	-	-	-	WHG domain
MHEPLEGL_00115	1.76e-127	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MHEPLEGL_00116	4.46e-127	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MHEPLEGL_00117	4.51e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MHEPLEGL_00118	3.16e-231	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MHEPLEGL_00119	1.28e-115	cvpA	-	-	S	-	-	-	Colicin V production protein
MHEPLEGL_00120	7.7e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
MHEPLEGL_00121	3.28e-193	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MHEPLEGL_00122	1.43e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
MHEPLEGL_00123	5.63e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MHEPLEGL_00124	6.38e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
MHEPLEGL_00125	4.85e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MHEPLEGL_00126	9.24e-176	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
MHEPLEGL_00127	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MHEPLEGL_00128	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MHEPLEGL_00129	1.68e-156	vanR	-	-	K	-	-	-	response regulator
MHEPLEGL_00130	3.1e-268	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
MHEPLEGL_00131	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MHEPLEGL_00132	5.48e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MHEPLEGL_00133	2.52e-95	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
MHEPLEGL_00134	7.4e-20	-	-	-	S	-	-	-	Enterocin A Immunity
MHEPLEGL_00135	9.97e-71	-	-	-	S	-	-	-	Enterocin A Immunity
MHEPLEGL_00136	6.23e-47	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
MHEPLEGL_00137	8.68e-44	-	-	-	-	-	-	-	-
MHEPLEGL_00138	5.7e-36	-	-	-	-	-	-	-	-
MHEPLEGL_00141	4.9e-180	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
MHEPLEGL_00142	1.79e-214	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MHEPLEGL_00143	1.67e-131	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MHEPLEGL_00144	3.33e-58	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MHEPLEGL_00145	5.69e-182	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
MHEPLEGL_00146	1.17e-15	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
MHEPLEGL_00147	1.41e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
MHEPLEGL_00148	1.34e-278	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
MHEPLEGL_00149	0.0	-	-	-	L	-	-	-	Probable transposase
MHEPLEGL_00150	2.21e-98	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MHEPLEGL_00151	3.81e-35	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MHEPLEGL_00152	6.97e-62	-	-	-	-	-	-	-	-
MHEPLEGL_00153	1.57e-100	-	-	-	-	-	-	-	-
MHEPLEGL_00154	1.71e-55	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
MHEPLEGL_00155	3e-58	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
MHEPLEGL_00156	4.44e-64	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
MHEPLEGL_00157	7.22e-198	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
MHEPLEGL_00158	1.84e-63	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
MHEPLEGL_00159	1.09e-18	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
MHEPLEGL_00160	2.58e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
MHEPLEGL_00161	1.54e-269	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MHEPLEGL_00162	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MHEPLEGL_00163	2.3e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MHEPLEGL_00164	2.99e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MHEPLEGL_00165	2.23e-232	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MHEPLEGL_00166	4.94e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MHEPLEGL_00167	1.37e-78	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MHEPLEGL_00168	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MHEPLEGL_00169	1.32e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
MHEPLEGL_00170	2.64e-63	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
MHEPLEGL_00171	6.53e-271	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MHEPLEGL_00172	1.18e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MHEPLEGL_00173	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHEPLEGL_00174	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MHEPLEGL_00175	1.57e-254	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MHEPLEGL_00176	1.62e-189	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MHEPLEGL_00177	1.91e-179	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MHEPLEGL_00178	8.57e-122	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MHEPLEGL_00179	5.02e-169	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MHEPLEGL_00180	5.27e-237	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MHEPLEGL_00181	2.69e-181	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MHEPLEGL_00182	1.1e-255	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
MHEPLEGL_00183	3.74e-148	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
MHEPLEGL_00184	1.09e-294	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
MHEPLEGL_00185	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MHEPLEGL_00186	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MHEPLEGL_00187	1.22e-25	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MHEPLEGL_00188	6.66e-114	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MHEPLEGL_00189	2.52e-192	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MHEPLEGL_00194	3.41e-35	qacA	-	-	EGP	-	-	-	Major Facilitator
MHEPLEGL_00195	1.17e-30	qacA	-	-	EGP	-	-	-	Major Facilitator
MHEPLEGL_00196	3.5e-285	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MHEPLEGL_00197	2.29e-224	degV1	-	-	S	-	-	-	DegV family
MHEPLEGL_00198	2.61e-195	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MHEPLEGL_00199	2.37e-49	sptS	-	-	T	-	-	-	Histidine kinase
MHEPLEGL_00200	1.02e-43	dltr	-	-	K	-	-	-	response regulator
MHEPLEGL_00201	1.11e-203	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
MHEPLEGL_00202	2.84e-150	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
MHEPLEGL_00203	1.08e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MHEPLEGL_00204	3.58e-66	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MHEPLEGL_00205	6.8e-166	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
MHEPLEGL_00206	3.24e-40	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MHEPLEGL_00207	3.8e-71	eutP	-	-	E	ko:K04029	-	ko00000	Ethanolamine utilisation - propanediol utilisation
MHEPLEGL_00208	2.64e-51	-	-	-	U	-	-	-	FFAT motif binding
MHEPLEGL_00209	4.09e-109	-	-	-	U	-	-	-	FFAT motif binding
MHEPLEGL_00210	1.01e-161	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF-type riboflavin transporter, S component
MHEPLEGL_00211	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MHEPLEGL_00212	1.19e-200	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type cobalt transport system permease component CbiQ and related transporters
MHEPLEGL_00214	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MHEPLEGL_00215	0.0	-	-	-	S	ko:K21449	-	ko00000,ko02000	Domain of unknown function (DUF4430)
MHEPLEGL_00216	5.25e-236	-	-	-	U	-	-	-	FFAT motif binding
MHEPLEGL_00217	1.84e-159	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
MHEPLEGL_00218	9.11e-198	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MHEPLEGL_00219	2.07e-204	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MHEPLEGL_00220	3.71e-60	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MHEPLEGL_00221	1.68e-85	-	-	-	L	-	-	-	Resolvase, N terminal domain
MHEPLEGL_00222	4.53e-41	-	-	-	S	-	-	-	Transglycosylase associated protein
MHEPLEGL_00223	3.1e-50	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
MHEPLEGL_00224	1.15e-93	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
MHEPLEGL_00225	3.8e-59	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
MHEPLEGL_00226	5.77e-102	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MHEPLEGL_00227	2.92e-103	-	-	-	K	-	-	-	Transcriptional regulator
MHEPLEGL_00228	3.15e-231	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHEPLEGL_00229	6.25e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHEPLEGL_00230	7.04e-217	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
MHEPLEGL_00231	1.09e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MHEPLEGL_00232	2.2e-293	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHEPLEGL_00233	5.23e-102	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MHEPLEGL_00234	6.93e-96	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
MHEPLEGL_00235	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
MHEPLEGL_00236	1.78e-202	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MHEPLEGL_00237	2.6e-183	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
MHEPLEGL_00238	2.68e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MHEPLEGL_00239	5.31e-240	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MHEPLEGL_00240	4.63e-119	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MHEPLEGL_00241	2.49e-190	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MHEPLEGL_00242	3.39e-72	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
MHEPLEGL_00243	2.18e-62	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
MHEPLEGL_00250	4.91e-35	-	-	-	-	-	-	-	-
MHEPLEGL_00251	6.8e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
MHEPLEGL_00252	6.71e-55	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MHEPLEGL_00253	1.64e-102	-	-	-	S	-	-	-	SLAP domain
MHEPLEGL_00254	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MHEPLEGL_00255	8.69e-192	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MHEPLEGL_00256	4.07e-52	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
MHEPLEGL_00257	8.47e-208	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MHEPLEGL_00258	3.64e-129	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MHEPLEGL_00259	9.48e-190	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
MHEPLEGL_00260	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MHEPLEGL_00261	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
MHEPLEGL_00262	6.75e-140	-	-	-	S	ko:K06872	-	ko00000	TPM domain
MHEPLEGL_00263	1.09e-118	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
MHEPLEGL_00264	2.86e-245	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MHEPLEGL_00265	1.08e-149	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
MHEPLEGL_00267	6.33e-148	-	-	-	-	-	-	-	-
MHEPLEGL_00268	2.07e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHEPLEGL_00269	2.48e-78	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MHEPLEGL_00270	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
MHEPLEGL_00271	3.61e-266	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MHEPLEGL_00272	2.51e-155	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MHEPLEGL_00273	0.0	pepC1	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
MHEPLEGL_00275	2.3e-71	-	-	-	-	-	-	-	-
MHEPLEGL_00276	8.92e-310	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MHEPLEGL_00277	0.0	-	-	-	S	-	-	-	Fibronectin type III domain
MHEPLEGL_00278	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
MHEPLEGL_00279	2.73e-146	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MHEPLEGL_00280	1.01e-255	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MHEPLEGL_00281	1.09e-129	-	-	-	G	-	-	-	Aldose 1-epimerase
MHEPLEGL_00282	3.47e-142	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MHEPLEGL_00283	1.57e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MHEPLEGL_00284	2.69e-27	-	-	-	-	-	-	-	-
MHEPLEGL_00285	3.78e-13	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (Permease)
MHEPLEGL_00286	4.33e-68	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
MHEPLEGL_00287	3.13e-53	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
MHEPLEGL_00288	8.09e-235	-	-	-	S	-	-	-	AAA domain
MHEPLEGL_00289	2.41e-164	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MHEPLEGL_00290	1.16e-31	-	-	-	-	-	-	-	-
MHEPLEGL_00291	1.52e-208	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
MHEPLEGL_00292	2.31e-162	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
MHEPLEGL_00293	2.02e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MHEPLEGL_00294	2.01e-18	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MHEPLEGL_00295	7.52e-62	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MHEPLEGL_00296	1.73e-139	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MHEPLEGL_00297	7.84e-92	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
MHEPLEGL_00298	1.01e-87	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MHEPLEGL_00299	2.27e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MHEPLEGL_00300	3.86e-193	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MHEPLEGL_00301	6.64e-182	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHEPLEGL_00302	1.58e-194	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHEPLEGL_00303	6.9e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHEPLEGL_00304	3.16e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MHEPLEGL_00305	4.41e-219	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHEPLEGL_00306	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MHEPLEGL_00307	1.46e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MHEPLEGL_00308	3.15e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MHEPLEGL_00309	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MHEPLEGL_00310	2.61e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MHEPLEGL_00311	5.1e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MHEPLEGL_00312	1.73e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MHEPLEGL_00313	2.22e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MHEPLEGL_00314	2.63e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MHEPLEGL_00315	1.28e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MHEPLEGL_00316	5.05e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MHEPLEGL_00317	2.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MHEPLEGL_00318	1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHEPLEGL_00319	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MHEPLEGL_00320	6.92e-45	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MHEPLEGL_00321	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MHEPLEGL_00322	6.37e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MHEPLEGL_00323	1.45e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MHEPLEGL_00324	1.66e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MHEPLEGL_00325	7.45e-158	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MHEPLEGL_00326	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MHEPLEGL_00327	4.33e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MHEPLEGL_00328	5.7e-198	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MHEPLEGL_00329	4.67e-63	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MHEPLEGL_00330	3.85e-137	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MHEPLEGL_00331	4.67e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MHEPLEGL_00332	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MHEPLEGL_00333	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MHEPLEGL_00334	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MHEPLEGL_00335	7.28e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MHEPLEGL_00336	8.38e-157	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
MHEPLEGL_00337	2.73e-240	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
MHEPLEGL_00338	2.86e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHEPLEGL_00339	6.01e-288	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MHEPLEGL_00340	7.76e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MHEPLEGL_00341	4.35e-125	-	-	-	-	-	-	-	-
MHEPLEGL_00342	5.07e-204	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MHEPLEGL_00343	9.47e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MHEPLEGL_00344	3.84e-233	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
MHEPLEGL_00345	1.87e-118	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
MHEPLEGL_00346	7.47e-128	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MHEPLEGL_00347	1.47e-210	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
MHEPLEGL_00348	1.84e-261	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MHEPLEGL_00349	6.45e-175	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MHEPLEGL_00350	3.23e-180	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MHEPLEGL_00351	8.14e-265	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MHEPLEGL_00352	8.69e-194	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MHEPLEGL_00353	6.17e-217	ybbR	-	-	S	-	-	-	YbbR-like protein
MHEPLEGL_00354	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MHEPLEGL_00355	2.06e-192	-	-	-	S	-	-	-	hydrolase
MHEPLEGL_00356	6.89e-191	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MHEPLEGL_00357	1.86e-153	-	-	-	-	-	-	-	-
MHEPLEGL_00358	2.06e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MHEPLEGL_00359	1.62e-263	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MHEPLEGL_00360	2.28e-81	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
MHEPLEGL_00361	7.38e-81	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
MHEPLEGL_00362	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHEPLEGL_00363	1.75e-189	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MHEPLEGL_00364	9.84e-149	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MHEPLEGL_00365	1.03e-236	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MHEPLEGL_00366	1.32e-20	-	-	-	E	-	-	-	Amino acid permease
MHEPLEGL_00367	0.0	-	-	-	E	-	-	-	Amino acid permease
MHEPLEGL_00371	5.05e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MHEPLEGL_00372	2.06e-109	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MHEPLEGL_00373	1.93e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MHEPLEGL_00374	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHEPLEGL_00375	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHEPLEGL_00376	1.79e-268	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MHEPLEGL_00377	2.87e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
MHEPLEGL_00378	5.84e-254	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MHEPLEGL_00379	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MHEPLEGL_00380	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
MHEPLEGL_00381	1.31e-81	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MHEPLEGL_00382	4.78e-192	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHEPLEGL_00383	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MHEPLEGL_00384	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MHEPLEGL_00385	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MHEPLEGL_00386	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MHEPLEGL_00387	8.22e-270	-	-	-	-	-	-	-	-
MHEPLEGL_00388	6.46e-27	-	-	-	-	-	-	-	-
MHEPLEGL_00389	4.51e-229	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
MHEPLEGL_00390	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MHEPLEGL_00391	1.81e-64	-	-	-	S	-	-	-	Cupredoxin-like domain
MHEPLEGL_00392	2.08e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
MHEPLEGL_00393	4.97e-102	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
MHEPLEGL_00394	8.31e-47	-	-	-	-	-	-	-	-
MHEPLEGL_00395	4.07e-288	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MHEPLEGL_00398	8.34e-66	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MHEPLEGL_00401	4.86e-26	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MHEPLEGL_00403	3.47e-214	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MHEPLEGL_00404	6.02e-20	-	-	-	M	-	-	-	Rib/alpha-like repeat
MHEPLEGL_00405	2.11e-86	-	-	-	-	-	-	-	-
MHEPLEGL_00406	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MHEPLEGL_00407	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MHEPLEGL_00408	2.53e-198	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MHEPLEGL_00409	4.1e-250	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MHEPLEGL_00410	6.52e-59	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
MHEPLEGL_00411	1.79e-214	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
MHEPLEGL_00412	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
MHEPLEGL_00413	1.5e-190	-	-	-	-	-	-	-	-
MHEPLEGL_00414	3.71e-281	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MHEPLEGL_00415	1.32e-85	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
MHEPLEGL_00416	1.01e-24	-	-	-	-	-	-	-	-
MHEPLEGL_00417	1.1e-190	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
MHEPLEGL_00418	3.24e-125	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MHEPLEGL_00419	1.09e-185	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MHEPLEGL_00420	3.07e-61	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
MHEPLEGL_00421	1.42e-36	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
MHEPLEGL_00422	6.67e-86	-	-	-	S	-	-	-	Domain of unknown function DUF1828
MHEPLEGL_00423	3.82e-23	-	-	-	-	-	-	-	-
MHEPLEGL_00424	1.97e-229	citR	-	-	K	-	-	-	Putative sugar-binding domain
MHEPLEGL_00425	9.28e-317	-	-	-	S	-	-	-	Putative threonine/serine exporter
MHEPLEGL_00426	2.45e-124	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
MHEPLEGL_00427	3.81e-143	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
MHEPLEGL_00428	7.45e-150	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MHEPLEGL_00429	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHEPLEGL_00430	5.45e-312	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
MHEPLEGL_00431	7.56e-65	-	-	-	-	-	-	-	-
MHEPLEGL_00432	7.31e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MHEPLEGL_00433	3.57e-143	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
MHEPLEGL_00434	3.23e-218	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
MHEPLEGL_00435	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHEPLEGL_00436	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MHEPLEGL_00437	2.94e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHEPLEGL_00438	9.26e-270	camS	-	-	S	-	-	-	sex pheromone
MHEPLEGL_00439	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MHEPLEGL_00440	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MHEPLEGL_00441	1.18e-142	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
MHEPLEGL_00443	8.06e-115	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MHEPLEGL_00444	4.18e-177	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
MHEPLEGL_00445	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MHEPLEGL_00446	2.57e-287	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MHEPLEGL_00447	7.33e-203	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MHEPLEGL_00448	3.35e-250	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MHEPLEGL_00449	2.13e-68	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MHEPLEGL_00450	1.15e-125	-	-	-	-	-	-	-	-
MHEPLEGL_00451	8.52e-212	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MHEPLEGL_00452	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
MHEPLEGL_00453	0.0	-	-	-	E	-	-	-	Amino acid permease
MHEPLEGL_00454	2.46e-07	-	-	-	-	-	-	-	-
MHEPLEGL_00455	4.12e-45	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MHEPLEGL_00456	2.1e-41	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MHEPLEGL_00457	1.42e-30	-	-	-	-	-	-	-	-
MHEPLEGL_00458	3.36e-54	-	-	-	-	-	-	-	-
MHEPLEGL_00459	2.69e-89	-	-	-	-	-	-	-	-
MHEPLEGL_00460	1.03e-316	-	-	-	L	-	-	-	DNA-dependent DNA replication
MHEPLEGL_00462	2.05e-07	-	-	-	S	-	-	-	Bacteriophage abortive infection AbiH
MHEPLEGL_00463	4.62e-07	-	-	-	S	-	-	-	Bacteriophage abortive infection AbiH
MHEPLEGL_00464	1.3e-291	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
MHEPLEGL_00465	4.54e-264	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
MHEPLEGL_00466	4.62e-251	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
MHEPLEGL_00467	1.01e-244	-	-	-	M	-	-	-	MobA-like NTP transferase domain
MHEPLEGL_00468	2.24e-103	-	-	-	M	-	-	-	MobA-like NTP transferase domain
MHEPLEGL_00469	4.12e-202	cudT	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
MHEPLEGL_00470	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHEPLEGL_00471	3.97e-140	pncA	-	-	Q	-	-	-	Isochorismatase family
MHEPLEGL_00472	2.09e-127	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
MHEPLEGL_00473	1.14e-118	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
MHEPLEGL_00475	9.1e-148	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA domain
MHEPLEGL_00476	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MHEPLEGL_00477	1.16e-202	ydhF	-	-	S	-	-	-	Aldo keto reductase
MHEPLEGL_00478	6.85e-226	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
MHEPLEGL_00479	8.61e-103	-	-	-	-	-	-	-	-
MHEPLEGL_00480	2.17e-05	-	-	-	C	-	-	-	FMN_bind
MHEPLEGL_00481	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
MHEPLEGL_00482	2.01e-128	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
MHEPLEGL_00483	9.93e-266	pbpX1	-	-	V	-	-	-	Beta-lactamase
MHEPLEGL_00484	6.08e-253	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MHEPLEGL_00485	1.24e-277	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MHEPLEGL_00486	5.66e-184	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MHEPLEGL_00487	8.96e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MHEPLEGL_00488	6.92e-282	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MHEPLEGL_00489	2.94e-108	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MHEPLEGL_00490	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MHEPLEGL_00491	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MHEPLEGL_00492	7.3e-245	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MHEPLEGL_00493	3.73e-230	potE	-	-	E	-	-	-	Amino Acid
MHEPLEGL_00494	3.89e-55	potE	-	-	E	-	-	-	Amino Acid
MHEPLEGL_00495	7.88e-137	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MHEPLEGL_00496	2.3e-295	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MHEPLEGL_00497	5.86e-281	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MHEPLEGL_00498	1.93e-285	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MHEPLEGL_00499	4.85e-194	-	-	-	-	-	-	-	-
MHEPLEGL_00500	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHEPLEGL_00501	1.48e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MHEPLEGL_00502	4.42e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MHEPLEGL_00503	2.46e-224	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MHEPLEGL_00504	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MHEPLEGL_00505	3.44e-130	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
MHEPLEGL_00506	6.48e-244	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MHEPLEGL_00507	1.37e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MHEPLEGL_00508	6.08e-125	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
MHEPLEGL_00509	1.72e-71	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
MHEPLEGL_00510	8.14e-265	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MHEPLEGL_00511	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MHEPLEGL_00512	1.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHEPLEGL_00513	9e-46	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MHEPLEGL_00514	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHEPLEGL_00515	1.83e-37	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MHEPLEGL_00517	3.81e-104	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MHEPLEGL_00518	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MHEPLEGL_00519	4.48e-145	-	-	-	S	-	-	-	repeat protein
MHEPLEGL_00520	6.42e-161	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
MHEPLEGL_00521	1.14e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MHEPLEGL_00522	2.01e-74	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
MHEPLEGL_00523	5.65e-277	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MHEPLEGL_00524	9.75e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MHEPLEGL_00525	9.02e-57	-	-	-	-	-	-	-	-
MHEPLEGL_00526	6.29e-135	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MHEPLEGL_00527	1.15e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MHEPLEGL_00528	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MHEPLEGL_00529	2.28e-161	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
MHEPLEGL_00530	1.4e-192	ylmH	-	-	S	-	-	-	S4 domain protein
MHEPLEGL_00531	5.07e-62	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
MHEPLEGL_00532	2.88e-96	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MHEPLEGL_00533	6.3e-267	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MHEPLEGL_00534	3.99e-300	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MHEPLEGL_00535	1.28e-193	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MHEPLEGL_00536	6e-268	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MHEPLEGL_00537	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MHEPLEGL_00538	3.96e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MHEPLEGL_00539	1.72e-56	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MHEPLEGL_00540	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MHEPLEGL_00541	1.88e-71	ftsL	-	-	D	-	-	-	Cell division protein FtsL
MHEPLEGL_00542	2.82e-233	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MHEPLEGL_00543	6.71e-44	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MHEPLEGL_00544	1.25e-26	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MHEPLEGL_00545	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MHEPLEGL_00546	4.81e-127	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MHEPLEGL_00547	4.91e-143	-	-	-	S	-	-	-	SNARE associated Golgi protein
MHEPLEGL_00548	1.71e-197	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MHEPLEGL_00549	2.77e-10	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
MHEPLEGL_00550	2.91e-164	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
MHEPLEGL_00551	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MHEPLEGL_00552	2.98e-201	-	-	-	-	-	-	-	-
MHEPLEGL_00553	4.44e-92	-	-	-	F	-	-	-	NUDIX domain
MHEPLEGL_00554	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
MHEPLEGL_00555	1.93e-125	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MHEPLEGL_00556	9.79e-209	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
MHEPLEGL_00557	2.02e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MHEPLEGL_00558	1.74e-309	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MHEPLEGL_00559	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
MHEPLEGL_00560	2.67e-185	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHEPLEGL_00561	1.4e-203	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
MHEPLEGL_00562	1.15e-257	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
MHEPLEGL_00563	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MHEPLEGL_00564	8.45e-203	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
MHEPLEGL_00565	1.31e-218	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
MHEPLEGL_00566	8.83e-204	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MHEPLEGL_00567	7.18e-86	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHEPLEGL_00568	2.08e-84	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHEPLEGL_00569	3.16e-58	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
MHEPLEGL_00570	4.32e-229	-	-	-	E	-	-	-	Amino acid permease
MHEPLEGL_00571	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
MHEPLEGL_00572	1.27e-313	ynbB	-	-	P	-	-	-	aluminum resistance
MHEPLEGL_00573	7.39e-95	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
MHEPLEGL_00574	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
MHEPLEGL_00575	9.2e-104	-	-	-	C	-	-	-	Flavodoxin
MHEPLEGL_00576	4.68e-145	-	-	-	I	-	-	-	Acid phosphatase homologues
MHEPLEGL_00577	1.46e-145	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MHEPLEGL_00578	1.3e-265	-	-	-	V	-	-	-	Beta-lactamase
MHEPLEGL_00579	7.49e-196	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
MHEPLEGL_00580	1.73e-121	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
MHEPLEGL_00581	5.84e-294	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
MHEPLEGL_00582	5.6e-178	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
MHEPLEGL_00583	1.17e-80	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
MHEPLEGL_00584	0.0	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MHEPLEGL_00585	3.94e-45	-	-	-	-	-	-	-	-
MHEPLEGL_00586	3.3e-79	-	-	-	-	-	-	-	-
MHEPLEGL_00587	7.59e-115	-	-	-	-	-	-	-	-
MHEPLEGL_00588	6.44e-90	-	-	-	-	-	-	-	-
MHEPLEGL_00589	8.79e-120	-	-	-	S	-	-	-	Fic/DOC family
MHEPLEGL_00590	9.1e-123	-	-	-	-	-	-	-	-
MHEPLEGL_00591	9.94e-35	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MHEPLEGL_00592	2.26e-196	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MHEPLEGL_00593	3.7e-173	-	-	-	-	-	-	-	-
MHEPLEGL_00594	1.21e-15	-	-	-	M	-	-	-	domain protein
MHEPLEGL_00596	4.04e-70	-	-	-	M	-	-	-	domain protein
MHEPLEGL_00598	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MHEPLEGL_00599	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MHEPLEGL_00600	4.08e-47	-	-	-	-	-	-	-	-
MHEPLEGL_00601	6.02e-83	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MHEPLEGL_00602	1.22e-133	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MHEPLEGL_00603	4.88e-131	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MHEPLEGL_00604	8.43e-240	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHEPLEGL_00605	5.32e-207	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MHEPLEGL_00606	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
MHEPLEGL_00607	7.3e-22	ps301	-	-	K	-	-	-	sequence-specific DNA binding
MHEPLEGL_00608	3.32e-124	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MHEPLEGL_00609	3.32e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MHEPLEGL_00611	3.22e-147	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MHEPLEGL_00612	1.08e-127	-	-	-	I	-	-	-	PAP2 superfamily
MHEPLEGL_00613	2.99e-138	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
MHEPLEGL_00614	4.14e-08	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
MHEPLEGL_00615	6.08e-312	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MHEPLEGL_00616	8.27e-111	yfhC	-	-	C	-	-	-	nitroreductase
MHEPLEGL_00617	2.18e-12	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MHEPLEGL_00618	4.37e-102	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MHEPLEGL_00619	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MHEPLEGL_00620	6.87e-171	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHEPLEGL_00621	3.65e-109	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
MHEPLEGL_00622	1.3e-199	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
MHEPLEGL_00625	2.22e-192	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MHEPLEGL_00626	7.15e-73	-	-	-	-	-	-	-	-
MHEPLEGL_00627	3.69e-180	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MHEPLEGL_00628	2.48e-175	mgtC3	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
MHEPLEGL_00629	2.72e-10	-	-	-	C	-	-	-	FMN-dependent dehydrogenase
MHEPLEGL_00630	7.28e-209	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MHEPLEGL_00631	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MHEPLEGL_00632	2.07e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MHEPLEGL_00633	1.43e-292	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
MHEPLEGL_00634	0.0	yhaN	-	-	L	-	-	-	AAA domain
MHEPLEGL_00635	2.85e-242	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
MHEPLEGL_00636	6.37e-102	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
MHEPLEGL_00637	1.27e-196	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MHEPLEGL_00638	1.39e-46	-	-	-	-	-	-	-	-
MHEPLEGL_00639	1.67e-104	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
MHEPLEGL_00640	8.03e-58	-	-	-	S	-	-	-	Plasmid maintenance system killer
MHEPLEGL_00641	4.8e-72	-	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
MHEPLEGL_00642	9.02e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHEPLEGL_00643	2.55e-269	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MHEPLEGL_00644	7.82e-161	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MHEPLEGL_00645	1.64e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
MHEPLEGL_00646	3.06e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHEPLEGL_00647	0.0	-	-	-	-	-	-	-	-
MHEPLEGL_00649	1.06e-122	-	-	-	-	-	-	-	-
MHEPLEGL_00650	2.83e-121	-	-	-	-	-	-	-	-
MHEPLEGL_00651	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MHEPLEGL_00652	4.39e-214	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MHEPLEGL_00653	7.51e-316	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
MHEPLEGL_00654	4.49e-107	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MHEPLEGL_00655	2.16e-136	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MHEPLEGL_00656	6.45e-203	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MHEPLEGL_00657	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MHEPLEGL_00658	9.43e-39	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MHEPLEGL_00659	6.26e-156	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MHEPLEGL_00660	1.46e-63	-	3.1.12.1	-	L	ko:K07464	-	ko00000,ko01000,ko02048	Domain of unknown function DUF83
MHEPLEGL_00661	3.78e-217	-	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
MHEPLEGL_00662	3.02e-84	-	-	-	L	ko:K19090	-	ko00000,ko02048	CRISPR-associated protein Cas5
MHEPLEGL_00663	1.37e-132	-	-	-	L	ko:K19075	-	ko00000,ko02048	CRISPR-associated negative auto-regulator DevR/Csa2
MHEPLEGL_00664	3.73e-126	-	-	-	S	ko:K19088	-	ko00000,ko02048	CRISPR-associated protein (Cas_CXXC_CXXC)
MHEPLEGL_00665	1.08e-52	-	-	-	L	ko:K19091	-	ko00000,ko01000,ko02048	CRISPR associated protein Cas6
MHEPLEGL_00666	2.14e-220	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MHEPLEGL_00667	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MHEPLEGL_00668	1.83e-188	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MHEPLEGL_00669	9.81e-165	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
MHEPLEGL_00670	1.34e-151	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
MHEPLEGL_00671	2.38e-31	-	-	-	K	-	-	-	rpiR family
MHEPLEGL_00672	3.68e-33	-	-	-	K	-	-	-	rpiR family
MHEPLEGL_00673	2.7e-172	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MHEPLEGL_00674	7.57e-207	-	-	-	S	-	-	-	Aldo/keto reductase family
MHEPLEGL_00675	3.27e-127	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MHEPLEGL_00676	7.42e-20	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHEPLEGL_00677	3.57e-204	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHEPLEGL_00678	1.32e-222	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHEPLEGL_00679	4e-16	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHEPLEGL_00680	1.79e-248	-	-	-	S	-	-	-	DUF218 domain
MHEPLEGL_00681	3.04e-154	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MHEPLEGL_00682	7.47e-63	-	-	-	-	-	-	-	-
MHEPLEGL_00683	9.96e-204	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MHEPLEGL_00684	7.26e-112	-	-	-	S	-	-	-	Putative adhesin
MHEPLEGL_00685	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
MHEPLEGL_00686	1.37e-63	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
MHEPLEGL_00687	9e-66	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
MHEPLEGL_00688	7.43e-259	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
MHEPLEGL_00689	0.0	cadA	-	-	P	-	-	-	P-type ATPase
MHEPLEGL_00690	1.76e-43	-	-	-	K	-	-	-	Helix-turn-helix domain
MHEPLEGL_00691	1.17e-73	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
MHEPLEGL_00692	9.25e-217	ldh3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
MHEPLEGL_00693	2.74e-89	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHEPLEGL_00694	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHEPLEGL_00695	7.75e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MHEPLEGL_00696	2.06e-82	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MHEPLEGL_00697	2.58e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHEPLEGL_00698	1.08e-53	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MHEPLEGL_00699	8.22e-203	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHEPLEGL_00700	1.37e-109	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
MHEPLEGL_00701	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHEPLEGL_00702	2.12e-164	csrR	-	-	K	-	-	-	response regulator
MHEPLEGL_00703	7.09e-125	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
MHEPLEGL_00704	3.81e-274	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MHEPLEGL_00705	7.23e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MHEPLEGL_00706	9.6e-143	yqeK	-	-	H	-	-	-	Hydrolase, HD family
MHEPLEGL_00707	5.48e-157	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MHEPLEGL_00708	4.97e-272	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
MHEPLEGL_00709	1.51e-121	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
MHEPLEGL_00710	1.23e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MHEPLEGL_00711	4.77e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MHEPLEGL_00712	1.44e-74	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MHEPLEGL_00713	1.93e-298	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
MHEPLEGL_00714	2.61e-36	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
MHEPLEGL_00715	6.44e-246	-	-	-	S	-	-	-	Domain of unknown function (DUF389)
MHEPLEGL_00716	7.73e-102	-	-	-	-	-	-	-	-
MHEPLEGL_00717	2.34e-181	-	-	-	-	-	-	-	-
MHEPLEGL_00718	8.63e-190	-	-	-	-	-	-	-	-
MHEPLEGL_00719	3.13e-160	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MHEPLEGL_00720	7.06e-81	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
MHEPLEGL_00721	2.1e-309	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MHEPLEGL_00722	1.15e-195	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MHEPLEGL_00723	1.82e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MHEPLEGL_00724	2.69e-40	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
MHEPLEGL_00725	1.4e-159	-	-	-	S	-	-	-	Peptidase family M23
MHEPLEGL_00726	8.62e-253	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MHEPLEGL_00727	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MHEPLEGL_00728	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MHEPLEGL_00729	1.5e-227	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MHEPLEGL_00730	1.62e-174	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MHEPLEGL_00731	2.56e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MHEPLEGL_00732	1.25e-129	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MHEPLEGL_00733	2.03e-223	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
MHEPLEGL_00734	5.12e-91	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
MHEPLEGL_00735	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MHEPLEGL_00736	7.77e-196	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MHEPLEGL_00737	5.68e-67	-	-	-	S	-	-	-	Peptidase family M23
MHEPLEGL_00738	1.07e-209	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHEPLEGL_00739	1.32e-86	-	-	-	-	-	-	-	-
MHEPLEGL_00740	3.62e-36	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
MHEPLEGL_00741	2.06e-250	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
MHEPLEGL_00742	5.58e-56	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
MHEPLEGL_00743	2.27e-81	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
MHEPLEGL_00744	2.25e-49	-	-	-	-	-	-	-	-
MHEPLEGL_00745	7.3e-40	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MHEPLEGL_00746	2.05e-42	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MHEPLEGL_00747	3.99e-260	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHEPLEGL_00748	2.36e-47	-	-	-	S	-	-	-	LPXTG cell wall anchor motif
MHEPLEGL_00749	1.8e-110	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MHEPLEGL_00750	9.09e-94	-	-	-	-	-	-	-	-
MHEPLEGL_00751	1.49e-73	-	-	-	E	-	-	-	amino acid
MHEPLEGL_00752	4.57e-49	-	-	-	E	-	-	-	amino acid
MHEPLEGL_00753	7.04e-63	-	-	-	-	-	-	-	-
MHEPLEGL_00754	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MHEPLEGL_00755	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MHEPLEGL_00756	3.96e-309	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MHEPLEGL_00757	1.43e-24	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MHEPLEGL_00758	8.1e-70	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MHEPLEGL_00759	6.54e-188	-	-	-	K	-	-	-	Transcriptional regulator
MHEPLEGL_00760	7.91e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
MHEPLEGL_00761	3.51e-222	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
MHEPLEGL_00762	6.03e-180	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
MHEPLEGL_00763	3.73e-239	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
MHEPLEGL_00764	1.47e-76	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
MHEPLEGL_00765	5.91e-20	scrA5	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHEPLEGL_00766	9.88e-83	scrA5	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHEPLEGL_00767	2.88e-18	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MHEPLEGL_00768	2.32e-51	-	-	-	K	-	-	-	LysR substrate binding domain
MHEPLEGL_00769	2.82e-80	-	-	-	K	-	-	-	LysR substrate binding domain
MHEPLEGL_00770	1.48e-10	-	-	-	K	-	-	-	LysR substrate binding domain
MHEPLEGL_00771	2.68e-142	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
MHEPLEGL_00772	1.31e-213	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
MHEPLEGL_00773	2.17e-205	-	-	-	M	-	-	-	Glycosyl transferase family 8
MHEPLEGL_00774	1.29e-13	-	-	-	M	-	-	-	Glycosyl transferase family 8
MHEPLEGL_00775	6.18e-238	-	-	-	M	-	-	-	Glycosyl transferase family 8
MHEPLEGL_00776	7.53e-203	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
MHEPLEGL_00777	1.46e-53	-	-	-	K	-	-	-	Helix-turn-helix domain
MHEPLEGL_00778	3.27e-107	-	-	-	K	-	-	-	Helix-turn-helix domain
MHEPLEGL_00779	8.43e-19	-	-	-	-	-	-	-	-
MHEPLEGL_00780	2.49e-87	-	-	-	-	-	-	-	-
MHEPLEGL_00781	1.25e-188	-	-	-	I	-	-	-	Acyl-transferase
MHEPLEGL_00782	9.34e-254	-	-	-	S	-	-	-	SLAP domain
MHEPLEGL_00783	3.02e-172	-	-	-	-	-	-	-	-
MHEPLEGL_00784	8.48e-214	-	-	-	S	-	-	-	SLAP domain
MHEPLEGL_00787	3.67e-45	-	-	-	-	-	-	-	-
MHEPLEGL_00789	2.8e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MHEPLEGL_00790	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHEPLEGL_00791	1.63e-313	yycH	-	-	S	-	-	-	YycH protein
MHEPLEGL_00792	7.14e-190	yycI	-	-	S	-	-	-	YycH protein
MHEPLEGL_00793	7.18e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
MHEPLEGL_00794	1.23e-276	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
MHEPLEGL_00795	5.48e-118	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MHEPLEGL_00796	2.72e-42	-	-	-	K	-	-	-	Helix-turn-helix domain
MHEPLEGL_00797	2.5e-148	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MHEPLEGL_00798	1.22e-170	-	-	-	K	-	-	-	Protein of unknown function (DUF4065)
MHEPLEGL_00799	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
MHEPLEGL_00800	2.86e-268	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
MHEPLEGL_00801	5.31e-284	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MHEPLEGL_00802	1.34e-126	-	-	-	-	-	-	-	-
MHEPLEGL_00803	1.06e-63	-	-	-	K	-	-	-	DNA-templated transcription, initiation
MHEPLEGL_00805	1.94e-213	-	-	-	S	-	-	-	SLAP domain
MHEPLEGL_00806	2.09e-41	-	-	-	-	-	-	-	-
MHEPLEGL_00807	4.85e-16	-	-	-	-	-	-	-	-
MHEPLEGL_00808	1.13e-97	-	-	-	-	-	-	-	-
MHEPLEGL_00809	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MHEPLEGL_00810	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MHEPLEGL_00811	1.09e-291	yttB	-	-	EGP	-	-	-	Major Facilitator
MHEPLEGL_00812	1.49e-294	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
MHEPLEGL_00813	5.57e-129	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MHEPLEGL_00814	1.35e-180	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MHEPLEGL_00815	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
MHEPLEGL_00818	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
MHEPLEGL_00819	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MHEPLEGL_00820	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MHEPLEGL_00821	1.05e-108	-	-	-	-	-	-	-	-
MHEPLEGL_00822	3.65e-139	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
MHEPLEGL_00823	2.22e-191	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHEPLEGL_00824	4.7e-170	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHEPLEGL_00825	6.34e-180	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MHEPLEGL_00826	6.24e-198	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
MHEPLEGL_00827	6.8e-115	usp5	-	-	T	-	-	-	universal stress protein
MHEPLEGL_00828	1.69e-189	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MHEPLEGL_00829	2.36e-116	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHEPLEGL_00830	8.67e-111	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
MHEPLEGL_00831	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
MHEPLEGL_00832	3.08e-43	-	-	-	-	-	-	-	-
MHEPLEGL_00833	1.07e-204	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MHEPLEGL_00834	4.71e-168	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
MHEPLEGL_00835	1.39e-257	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
MHEPLEGL_00836	1.26e-144	-	-	-	-	-	-	-	-
MHEPLEGL_00837	8.82e-266	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MHEPLEGL_00838	6.74e-285	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
MHEPLEGL_00839	1.05e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MHEPLEGL_00840	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MHEPLEGL_00841	4.16e-173	-	-	-	-	-	-	-	-
MHEPLEGL_00842	1.82e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MHEPLEGL_00843	2.92e-232	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHEPLEGL_00844	1.17e-85	-	-	-	-	-	-	-	-
MHEPLEGL_00845	1.2e-148	-	-	-	GM	-	-	-	NmrA-like family
MHEPLEGL_00846	2.62e-164	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MHEPLEGL_00847	5.32e-204	epsV	-	-	S	-	-	-	glycosyl transferase family 2
MHEPLEGL_00848	2.71e-182	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
MHEPLEGL_00849	5.07e-188	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHEPLEGL_00850	1.97e-229	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MHEPLEGL_00851	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHEPLEGL_00852	4.64e-111	-	-	-	-	-	-	-	-
MHEPLEGL_00853	5.53e-61	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
MHEPLEGL_00854	6.16e-81	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
MHEPLEGL_00855	1.25e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
MHEPLEGL_00856	3.66e-161	terC	-	-	P	-	-	-	Integral membrane protein TerC family
MHEPLEGL_00857	2.78e-82	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
MHEPLEGL_00858	6.21e-159	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MHEPLEGL_00859	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MHEPLEGL_00860	2.21e-177	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MHEPLEGL_00861	2.34e-204	-	-	-	L	-	-	-	HNH nucleases
MHEPLEGL_00862	6.43e-159	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
MHEPLEGL_00864	4.32e-25	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MHEPLEGL_00865	5.67e-84	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
MHEPLEGL_00866	5.55e-30	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
MHEPLEGL_00867	1.43e-13	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
MHEPLEGL_00868	2.33e-224	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
MHEPLEGL_00869	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
MHEPLEGL_00870	1.22e-166	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MHEPLEGL_00871	7.11e-41	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MHEPLEGL_00872	6.28e-222	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MHEPLEGL_00873	2.03e-187	-	-	-	K	-	-	-	SIS domain
MHEPLEGL_00874	2.66e-310	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MHEPLEGL_00875	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MHEPLEGL_00876	4.12e-254	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MHEPLEGL_00877	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MHEPLEGL_00878	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHEPLEGL_00879	2.61e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHEPLEGL_00880	1.01e-51	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHEPLEGL_00881	2.92e-171	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MHEPLEGL_00882	1.39e-278	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MHEPLEGL_00883	4.1e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MHEPLEGL_00884	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
MHEPLEGL_00885	3.26e-175	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MHEPLEGL_00886	8.46e-13	-	-	-	G	-	-	-	Major Facilitator Superfamily
MHEPLEGL_00887	3.98e-64	-	-	-	G	-	-	-	Major Facilitator Superfamily
MHEPLEGL_00888	1.46e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
MHEPLEGL_00889	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MHEPLEGL_00890	1.28e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MHEPLEGL_00891	5.69e-195	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MHEPLEGL_00892	2.8e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MHEPLEGL_00893	8.52e-130	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MHEPLEGL_00894	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
MHEPLEGL_00895	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MHEPLEGL_00896	7.56e-106	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
MHEPLEGL_00897	9.06e-192	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MHEPLEGL_00898	2.62e-166	-	-	-	F	-	-	-	glutamine amidotransferase
MHEPLEGL_00899	1.58e-161	-	-	-	-	-	-	-	-
MHEPLEGL_00900	1.18e-14	-	-	-	-	-	-	-	-
MHEPLEGL_00901	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
MHEPLEGL_00902	2.17e-266	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
MHEPLEGL_00903	1.35e-265	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
MHEPLEGL_00904	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
MHEPLEGL_00906	4.66e-117	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MHEPLEGL_00907	3.23e-305	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
MHEPLEGL_00909	1.22e-81	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MHEPLEGL_00910	6.83e-48	dar	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
MHEPLEGL_00911	5.17e-123	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
MHEPLEGL_00912	8.39e-279	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MHEPLEGL_00913	2.45e-216	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MHEPLEGL_00914	9.52e-32	-	-	-	-	-	-	-	-
MHEPLEGL_00915	3.06e-46	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MHEPLEGL_00919	1.31e-148	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
MHEPLEGL_00920	1.01e-276	-	-	-	EGP	-	-	-	Major facilitator Superfamily
MHEPLEGL_00921	5.28e-140	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
MHEPLEGL_00922	2.49e-114	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MHEPLEGL_00923	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MHEPLEGL_00924	3.05e-160	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
MHEPLEGL_00925	6.85e-106	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MHEPLEGL_00926	1.55e-233	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
MHEPLEGL_00927	3.79e-125	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
MHEPLEGL_00928	8.78e-33	ykuL	-	-	S	-	-	-	IMP dehydrogenase activity
MHEPLEGL_00929	1.89e-276	-	-	-	S	-	-	-	Membrane
MHEPLEGL_00930	9.91e-68	-	-	-	-	-	-	-	-
MHEPLEGL_00931	6.46e-27	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
MHEPLEGL_00932	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHEPLEGL_00933	1.12e-308	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
MHEPLEGL_00934	2.46e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHEPLEGL_00935	6.8e-316	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MHEPLEGL_00936	3.24e-222	pbpX2	-	-	V	-	-	-	Beta-lactamase
MHEPLEGL_00937	1.38e-163	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MHEPLEGL_00938	5.65e-38	-	-	-	-	-	-	-	-
MHEPLEGL_00939	6.74e-67	-	-	-	-	-	-	-	-
MHEPLEGL_00940	1.65e-121	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
MHEPLEGL_00941	2.67e-186	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MHEPLEGL_00942	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MHEPLEGL_00943	6.61e-55	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MHEPLEGL_00945	2.6e-44	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
MHEPLEGL_00946	3.92e-172	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
MHEPLEGL_00947	1.34e-153	-	-	-	C	-	-	-	Aldo keto reductase
MHEPLEGL_00948	8.1e-104	-	-	-	GM	-	-	-	NAD(P)H-binding
MHEPLEGL_00949	1.85e-22	-	-	-	-	-	-	-	-
MHEPLEGL_00951	7.59e-260	-	-	-	G	-	-	-	Major Facilitator Superfamily
MHEPLEGL_00952	2.48e-60	-	-	-	-	-	-	-	-
MHEPLEGL_00953	3.49e-10	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
MHEPLEGL_00954	1.9e-31	-	-	-	O	-	-	-	Matrixin
MHEPLEGL_00955	3.93e-283	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MHEPLEGL_00956	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MHEPLEGL_00957	8.3e-97	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MHEPLEGL_00958	1.49e-39	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MHEPLEGL_00959	4.07e-71	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MHEPLEGL_00960	8.07e-45	-	-	-	S	ko:K18918	-	ko00000,ko02048,ko03000	RelB antitoxin
MHEPLEGL_00961	2.34e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MHEPLEGL_00962	2.69e-165	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MHEPLEGL_00963	5.1e-211	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MHEPLEGL_00964	5.02e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MHEPLEGL_00965	8.08e-234	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MHEPLEGL_00966	1.75e-314	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MHEPLEGL_00967	1.21e-268	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MHEPLEGL_00968	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MHEPLEGL_00969	5.37e-24	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MHEPLEGL_00970	1.62e-62	-	-	-	-	-	-	-	-
MHEPLEGL_00971	2.81e-278	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
MHEPLEGL_00972	2.8e-277	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
MHEPLEGL_00973	6.11e-277	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MHEPLEGL_00974	2.97e-276	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MHEPLEGL_00975	5.15e-216	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MHEPLEGL_00976	3.77e-197	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MHEPLEGL_00977	1.72e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
MHEPLEGL_00978	3.48e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MHEPLEGL_00979	2.9e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
MHEPLEGL_00980	2.12e-274	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MHEPLEGL_00981	2.14e-35	-	-	-	-	-	-	-	-
MHEPLEGL_00983	2.82e-315	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHEPLEGL_00984	1.46e-265	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
MHEPLEGL_00985	1.9e-165	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MHEPLEGL_00986	3.42e-297	-	-	-	E	ko:K03294	-	ko00000	amino acid
MHEPLEGL_00987	6.05e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MHEPLEGL_00988	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
MHEPLEGL_00989	1.69e-41	-	-	-	C	-	-	-	nitroreductase
MHEPLEGL_00990	3.42e-19	-	-	-	C	-	-	-	nitroreductase
MHEPLEGL_00991	7.15e-45	-	-	-	-	-	-	-	-
MHEPLEGL_00992	4.88e-198	yhaX	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MHEPLEGL_00993	5.28e-53	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MHEPLEGL_00994	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MHEPLEGL_00995	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MHEPLEGL_00996	9.04e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MHEPLEGL_00997	2.2e-274	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MHEPLEGL_00998	9.33e-119	-	-	-	K	-	-	-	transcriptional regulator
MHEPLEGL_00999	3.54e-166	-	-	-	S	-	-	-	(CBS) domain
MHEPLEGL_01000	2.81e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MHEPLEGL_01001	4.45e-133	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MHEPLEGL_01002	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MHEPLEGL_01003	1.26e-46	yabO	-	-	J	-	-	-	S4 domain protein
MHEPLEGL_01004	1.52e-77	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MHEPLEGL_01005	4.62e-81	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
MHEPLEGL_01006	4.41e-309	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MHEPLEGL_01007	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MHEPLEGL_01008	1.53e-211	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MHEPLEGL_01009	3.69e-197	-	-	-	K	ko:K09705	-	ko00000	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MHEPLEGL_01010	2.64e-28	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MHEPLEGL_01011	5.14e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MHEPLEGL_01012	0.0	-	-	-	V	-	-	-	Restriction endonuclease
MHEPLEGL_01013	2.59e-93	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MHEPLEGL_01014	1.5e-191	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MHEPLEGL_01015	1.37e-306	-	-	-	S	-	-	-	LPXTG cell wall anchor motif
MHEPLEGL_01016	1.11e-189	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MHEPLEGL_01017	1.09e-129	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
MHEPLEGL_01018	9.05e-114	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
MHEPLEGL_01019	2.05e-77	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
MHEPLEGL_01020	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
MHEPLEGL_01021	2.09e-224	ydbI	-	-	K	-	-	-	AI-2E family transporter
MHEPLEGL_01022	1.67e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MHEPLEGL_01023	1.73e-24	-	-	-	-	-	-	-	-
MHEPLEGL_01024	1.69e-68	-	-	-	-	-	-	-	-
MHEPLEGL_01025	4.47e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHEPLEGL_01026	1.59e-164	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MHEPLEGL_01027	5.19e-227	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
MHEPLEGL_01028	1.51e-176	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MHEPLEGL_01029	3.18e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
MHEPLEGL_01030	6.44e-50	ynzC	-	-	S	-	-	-	UPF0291 protein
MHEPLEGL_01031	2.07e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MHEPLEGL_01032	9.1e-191	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MHEPLEGL_01033	1.5e-106	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
MHEPLEGL_01034	2.28e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MHEPLEGL_01035	3.42e-175	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MHEPLEGL_01036	4.2e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MHEPLEGL_01037	2.36e-60	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MHEPLEGL_01038	1.34e-289	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MHEPLEGL_01039	1.17e-73	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MHEPLEGL_01040	2.6e-175	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MHEPLEGL_01041	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
MHEPLEGL_01042	7.95e-59	-	-	-	-	-	-	-	-
MHEPLEGL_01043	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MHEPLEGL_01044	3.45e-234	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MHEPLEGL_01045	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MHEPLEGL_01046	1.56e-161	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MHEPLEGL_01048	1.03e-268	XK27_02480	-	-	EGP	-	-	-	Major facilitator Superfamily
MHEPLEGL_01049	7.78e-200	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
MHEPLEGL_01050	5.18e-151	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MHEPLEGL_01051	8.31e-130	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MHEPLEGL_01052	6.79e-114	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MHEPLEGL_01053	4.3e-126	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHEPLEGL_01054	1.26e-09	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHEPLEGL_01055	2.87e-274	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHEPLEGL_01056	1.43e-199	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MHEPLEGL_01057	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
MHEPLEGL_01058	3.58e-155	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MHEPLEGL_01059	8.81e-165	-	-	-	-	-	-	-	-
MHEPLEGL_01060	1.95e-307	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MHEPLEGL_01061	7.16e-312	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MHEPLEGL_01062	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MHEPLEGL_01063	1.18e-66	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MHEPLEGL_01064	6.59e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MHEPLEGL_01065	5.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MHEPLEGL_01066	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MHEPLEGL_01067	1.2e-45	-	-	-	-	-	-	-	-
MHEPLEGL_01068	9.06e-53	-	-	-	-	-	-	-	-
MHEPLEGL_01069	1.51e-57	-	-	-	-	-	-	-	-
MHEPLEGL_01070	1.19e-315	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MHEPLEGL_01071	1.63e-233	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
MHEPLEGL_01072	2.09e-112	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHEPLEGL_01073	3.96e-135	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHEPLEGL_01074	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MHEPLEGL_01075	9.3e-82	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MHEPLEGL_01076	2.16e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MHEPLEGL_01077	2.53e-133	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MHEPLEGL_01078	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MHEPLEGL_01079	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MHEPLEGL_01080	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MHEPLEGL_01081	9.06e-60	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MHEPLEGL_01082	3.26e-202	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MHEPLEGL_01083	3.28e-29	-	-	-	K	-	-	-	transcriptional
MHEPLEGL_01084	1.46e-37	-	-	-	-	-	-	-	-
MHEPLEGL_01085	1.36e-30	-	-	-	-	-	-	-	-
MHEPLEGL_01088	3.63e-46	-	-	-	-	-	-	-	-
MHEPLEGL_01089	0.000381	-	-	-	S	-	-	-	Helix-turn-helix domain
MHEPLEGL_01090	3.48e-16	-	-	-	-	-	-	-	-
MHEPLEGL_01091	3.95e-113	-	-	-	-	-	-	-	-
MHEPLEGL_01092	6.11e-59	-	-	-	-	-	-	-	-
MHEPLEGL_01093	7.61e-132	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHEPLEGL_01094	2.98e-29	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
MHEPLEGL_01095	1.2e-18	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
MHEPLEGL_01096	2.49e-118	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
MHEPLEGL_01097	8.84e-162	-	-	-	S	-	-	-	membrane
MHEPLEGL_01098	4.52e-101	-	-	-	K	-	-	-	LytTr DNA-binding domain
MHEPLEGL_01099	4.32e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MHEPLEGL_01100	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
MHEPLEGL_01101	1.78e-17	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MHEPLEGL_01102	3.56e-135	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MHEPLEGL_01103	4.83e-67	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MHEPLEGL_01104	7.38e-47	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MHEPLEGL_01105	1.52e-140	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MHEPLEGL_01106	1.47e-06	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MHEPLEGL_01107	3.07e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MHEPLEGL_01108	1.07e-133	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
MHEPLEGL_01109	1.14e-171	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
MHEPLEGL_01110	2.61e-112	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MHEPLEGL_01111	9.84e-182	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
MHEPLEGL_01112	8.11e-201	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MHEPLEGL_01113	1.99e-80	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MHEPLEGL_01114	4.16e-199	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MHEPLEGL_01115	1.52e-68	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
MHEPLEGL_01116	8.42e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MHEPLEGL_01117	3.33e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MHEPLEGL_01118	6.48e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MHEPLEGL_01119	6.03e-57	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MHEPLEGL_01120	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHEPLEGL_01121	9.21e-120	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MHEPLEGL_01122	1.64e-149	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
MHEPLEGL_01123	6.04e-104	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
MHEPLEGL_01124	6.55e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MHEPLEGL_01125	3.72e-111	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MHEPLEGL_01126	7.86e-178	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MHEPLEGL_01127	1.88e-34	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MHEPLEGL_01128	1.67e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MHEPLEGL_01129	2.31e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHEPLEGL_01130	1.5e-186	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHEPLEGL_01131	9.02e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MHEPLEGL_01132	1.41e-220	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MHEPLEGL_01133	2.71e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MHEPLEGL_01134	2.02e-108	-	-	-	S	-	-	-	SLAP domain
MHEPLEGL_01135	4.44e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHEPLEGL_01136	8.08e-68	-	-	-	GK	-	-	-	ROK family
MHEPLEGL_01137	6.28e-85	-	-	-	GK	-	-	-	ROK family
MHEPLEGL_01138	5.78e-57	-	-	-	-	-	-	-	-
MHEPLEGL_01139	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MHEPLEGL_01140	8.23e-88	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
MHEPLEGL_01141	1.25e-114	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MHEPLEGL_01142	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MHEPLEGL_01143	1.28e-310	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHEPLEGL_01144	5.53e-43	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MHEPLEGL_01145	2.55e-64	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MHEPLEGL_01146	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MHEPLEGL_01147	3.33e-204	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
MHEPLEGL_01148	1.53e-287	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
MHEPLEGL_01149	6.78e-136	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MHEPLEGL_01150	6.07e-136	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
MHEPLEGL_01151	9.14e-22	-	-	-	S	-	-	-	Bacteriocin helveticin-J
MHEPLEGL_01152	1.08e-10	-	-	-	S	-	-	-	SLAP domain
MHEPLEGL_01153	2.21e-242	-	-	-	S	-	-	-	SLAP domain
MHEPLEGL_01154	8.57e-211	yvgN	-	-	C	-	-	-	Aldo keto reductase
MHEPLEGL_01155	0.0	fusA1	-	-	J	-	-	-	elongation factor G
MHEPLEGL_01156	1.5e-81	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	haloacid dehalogenase-like hydrolase
MHEPLEGL_01157	3.22e-80	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	haloacid dehalogenase-like hydrolase
MHEPLEGL_01158	2.64e-244	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHEPLEGL_01159	3.92e-215	-	-	-	G	-	-	-	Phosphotransferase enzyme family
MHEPLEGL_01160	1.25e-204	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MHEPLEGL_01161	1.77e-56	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
MHEPLEGL_01162	2.43e-34	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
MHEPLEGL_01163	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MHEPLEGL_01164	5.59e-250	pbpX1	-	-	V	-	-	-	Beta-lactamase
MHEPLEGL_01165	7.23e-93	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
MHEPLEGL_01166	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
MHEPLEGL_01167	2.45e-101	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MHEPLEGL_01168	6.05e-73	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MHEPLEGL_01169	7.74e-16	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MHEPLEGL_01170	2.11e-15	-	-	-	-	-	-	-	-
MHEPLEGL_01171	1.16e-59	-	-	-	L	-	-	-	Transposase DDE domain
MHEPLEGL_01173	1.12e-213	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
MHEPLEGL_01174	0.0	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
MHEPLEGL_01175	1.26e-246	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
MHEPLEGL_01176	6.62e-16	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
MHEPLEGL_01177	1.77e-46	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MHEPLEGL_01178	8.04e-46	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MHEPLEGL_01179	5.1e-88	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MHEPLEGL_01181	1.31e-287	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
MHEPLEGL_01182	1.31e-29	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
MHEPLEGL_01183	4.61e-223	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MHEPLEGL_01184	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHEPLEGL_01185	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHEPLEGL_01186	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MHEPLEGL_01187	7.84e-106	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MHEPLEGL_01190	1.77e-103	-	-	-	-	-	-	-	-
MHEPLEGL_01192	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MHEPLEGL_01193	8.27e-250	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHEPLEGL_01194	1.86e-63	-	-	-	-	-	-	-	-
MHEPLEGL_01195	1.9e-63	-	-	-	-	-	-	-	-
MHEPLEGL_01196	7.78e-158	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
MHEPLEGL_01197	6.04e-194	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MHEPLEGL_01198	5.12e-71	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MHEPLEGL_01199	1.43e-11	-	-	-	M	-	-	-	NlpC/P60 family
MHEPLEGL_01200	6.17e-28	-	-	-	M	-	-	-	NlpC/P60 family
MHEPLEGL_01201	4.61e-116	-	-	-	M	-	-	-	NlpC/P60 family
MHEPLEGL_01202	7.81e-190	-	-	-	G	-	-	-	Peptidase_C39 like family
MHEPLEGL_01203	3.8e-35	-	-	-	-	-	-	-	-
MHEPLEGL_01204	1.55e-89	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	DEAD/DEAH box helicase
MHEPLEGL_01205	4.57e-296	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
MHEPLEGL_01206	3.09e-118	-	-	-	-	-	-	-	-
MHEPLEGL_01207	7.06e-175	-	-	-	-	-	-	-	-
MHEPLEGL_01208	6.78e-137	-	-	-	-	-	-	-	-
MHEPLEGL_01209	9.3e-162	-	-	-	S	-	-	-	L-ascorbic acid biosynthetic process
MHEPLEGL_01210	2.64e-94	-	-	-	O	-	-	-	OsmC-like protein
MHEPLEGL_01211	3.34e-267	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MHEPLEGL_01212	2.42e-148	sptS	-	-	T	-	-	-	Histidine kinase
MHEPLEGL_01213	2.37e-49	sptS	-	-	T	-	-	-	Histidine kinase
MHEPLEGL_01214	1.02e-43	dltr	-	-	K	-	-	-	response regulator
MHEPLEGL_01215	1.16e-118	-	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
MHEPLEGL_01216	4.08e-248	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
MHEPLEGL_01217	2.14e-257	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
MHEPLEGL_01220	1.38e-219	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MHEPLEGL_01221	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MHEPLEGL_01222	7.13e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MHEPLEGL_01223	4.11e-75	-	-	-	-	-	-	-	-
MHEPLEGL_01224	1.18e-113	-	-	-	-	-	-	-	-
MHEPLEGL_01225	6.45e-66	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
MHEPLEGL_01226	2.02e-86	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
MHEPLEGL_01227	1.42e-193	-	-	-	S	-	-	-	DUF218 domain
MHEPLEGL_01228	4.04e-92	-	-	-	-	-	-	-	-
MHEPLEGL_01229	4.37e-116	-	-	-	-	-	-	-	-
MHEPLEGL_01230	9.26e-175	-	-	-	EG	-	-	-	EamA-like transporter family
MHEPLEGL_01231	1.96e-108	-	-	-	M	-	-	-	NlpC/P60 family
MHEPLEGL_01232	7.16e-71	-	-	-	-	-	-	-	-
MHEPLEGL_01233	7.71e-133	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
MHEPLEGL_01234	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MHEPLEGL_01235	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MHEPLEGL_01236	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MHEPLEGL_01237	2.1e-99	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MHEPLEGL_01238	1.76e-178	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHEPLEGL_01239	2.12e-120	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
MHEPLEGL_01240	2.41e-45	-	-	-	-	-	-	-	-
MHEPLEGL_01241	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MHEPLEGL_01242	4.41e-104	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MHEPLEGL_01243	2.43e-190	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MHEPLEGL_01244	6.67e-79	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MHEPLEGL_01245	8.53e-34	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MHEPLEGL_01246	5.2e-132	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MHEPLEGL_01247	7.71e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MHEPLEGL_01248	3.02e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MHEPLEGL_01249	5.73e-120	-	-	-	S	-	-	-	VanZ like family
MHEPLEGL_01250	1.09e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
MHEPLEGL_01251	8.35e-230	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
MHEPLEGL_01252	5.57e-224	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
MHEPLEGL_01253	6.15e-66	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
MHEPLEGL_01254	1.18e-94	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
MHEPLEGL_01255	1.18e-55	-	-	-	-	-	-	-	-
MHEPLEGL_01256	2.17e-108	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
MHEPLEGL_01257	1.15e-236	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
MHEPLEGL_01258	9.53e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHEPLEGL_01260	1.32e-50	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
MHEPLEGL_01261	7.36e-47	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
MHEPLEGL_01262	1.3e-191	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
MHEPLEGL_01263	3.93e-222	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MHEPLEGL_01264	3.87e-80	-	-	-	S	-	-	-	SdpI/YhfL protein family
MHEPLEGL_01265	9.37e-169	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
MHEPLEGL_01266	0.0	yclK	-	-	T	-	-	-	Histidine kinase
MHEPLEGL_01267	1.11e-283	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MHEPLEGL_01268	7.05e-248	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MHEPLEGL_01269	4.48e-183	epsB	-	-	M	-	-	-	biosynthesis protein
MHEPLEGL_01270	1.88e-159	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
MHEPLEGL_01271	1.2e-188	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
MHEPLEGL_01272	6.48e-156	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
MHEPLEGL_01273	3.18e-164	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
MHEPLEGL_01274	5.87e-123	-	-	-	S	-	-	-	Glycosyltransferase like family 2
MHEPLEGL_01275	1.02e-122	-	-	-	M	-	-	-	Glycosyl transferases group 1
MHEPLEGL_01276	7.8e-132	-	-	-	-	-	-	-	-
MHEPLEGL_01277	4.03e-69	-	-	-	S	-	-	-	Glycosyltransferase like family 2
MHEPLEGL_01278	7.33e-71	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MHEPLEGL_01279	2.14e-11	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
MHEPLEGL_01280	2.43e-101	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MHEPLEGL_01281	2.57e-44	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MHEPLEGL_01282	3.48e-75	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin
MHEPLEGL_01283	2.51e-152	-	-	-	K	-	-	-	Rhodanese Homology Domain
MHEPLEGL_01284	3.8e-222	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MHEPLEGL_01285	2.03e-30	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
MHEPLEGL_01286	3.38e-59	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
MHEPLEGL_01287	5.82e-36	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MHEPLEGL_01288	3.61e-215	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
MHEPLEGL_01289	1.92e-50	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
MHEPLEGL_01290	7.41e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
MHEPLEGL_01292	5.19e-310	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MHEPLEGL_01293	1.83e-196	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MHEPLEGL_01294	9.06e-159	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
MHEPLEGL_01295	6.14e-32	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
MHEPLEGL_01296	1.27e-311	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MHEPLEGL_01297	3.19e-41	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MHEPLEGL_01298	1.43e-163	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MHEPLEGL_01299	3.6e-50	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MHEPLEGL_01300	1.05e-205	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
MHEPLEGL_01301	1.33e-296	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
MHEPLEGL_01302	2.25e-301	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MHEPLEGL_01303	4.09e-80	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
MHEPLEGL_01304	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MHEPLEGL_01305	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MHEPLEGL_01306	9.5e-62	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
MHEPLEGL_01307	5.12e-296	-	-	-	-	-	-	-	-
MHEPLEGL_01308	6.27e-57	-	-	-	-	-	-	-	-
MHEPLEGL_01309	9e-34	-	-	-	-	-	-	-	-
MHEPLEGL_01310	0.0	-	-	-	S	-	-	-	PglZ domain
MHEPLEGL_01311	2.45e-94	-	-	-	S	-	-	-	SIR2-like domain
MHEPLEGL_01312	0.0	-	-	-	V	-	-	-	Eco57I restriction-modification methylase
MHEPLEGL_01313	1.96e-255	-	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
MHEPLEGL_01314	8.2e-145	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
MHEPLEGL_01315	4.51e-134	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
MHEPLEGL_01316	8.41e-295	-	-	-	S	-	-	-	Protein of unknown function DUF262
MHEPLEGL_01317	7.65e-42	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	lactoylglutathione lyase activity
MHEPLEGL_01318	2.16e-16	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	lactoylglutathione lyase activity
MHEPLEGL_01319	8.54e-87	-	-	-	S	-	-	-	ASCH domain
MHEPLEGL_01320	1.05e-142	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHEPLEGL_01321	7.07e-106	-	-	-	-	-	-	-	-
MHEPLEGL_01322	0.0	-	-	-	-	-	-	-	-
MHEPLEGL_01323	1.39e-121	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
MHEPLEGL_01324	8.05e-91	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
MHEPLEGL_01325	9.66e-161	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
MHEPLEGL_01326	4.39e-160	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
MHEPLEGL_01327	2.4e-64	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MHEPLEGL_01328	5.65e-76	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MHEPLEGL_01329	1.65e-55	-	-	-	-	-	-	-	-
MHEPLEGL_01330	9.54e-49	-	-	-	-	-	-	-	-
MHEPLEGL_01331	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
MHEPLEGL_01332	6.23e-45	-	-	-	KLT	-	-	-	serine threonine protein kinase
MHEPLEGL_01333	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
MHEPLEGL_01334	4.25e-190	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MHEPLEGL_01335	3.51e-118	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	domain protein
MHEPLEGL_01336	9e-189	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MHEPLEGL_01337	9.74e-98	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MHEPLEGL_01338	4.82e-26	-	-	-	K	-	-	-	LytTr DNA-binding domain
MHEPLEGL_01339	1.31e-139	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
MHEPLEGL_01341	2.21e-08	-	-	-	S	-	-	-	Protein of unknown function (DUF3923)
MHEPLEGL_01342	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
MHEPLEGL_01343	5.75e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MHEPLEGL_01344	3.33e-15	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MHEPLEGL_01345	1.73e-64	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MHEPLEGL_01347	1e-107	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
MHEPLEGL_01348	4.45e-83	-	-	-	-	-	-	-	-
MHEPLEGL_01350	3.74e-154	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
MHEPLEGL_01351	1.51e-185	-	-	-	F	-	-	-	Phosphorylase superfamily
MHEPLEGL_01352	2.06e-79	codA	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
MHEPLEGL_01354	6.41e-106	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MHEPLEGL_01355	6.89e-68	-	-	-	-	-	-	-	-
MHEPLEGL_01356	3.25e-96	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
MHEPLEGL_01357	9.58e-28	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
MHEPLEGL_01358	6.08e-224	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
MHEPLEGL_01359	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MHEPLEGL_01360	3.83e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MHEPLEGL_01361	4.22e-215	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MHEPLEGL_01362	2.54e-209	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
MHEPLEGL_01363	8.24e-163	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MHEPLEGL_01364	4.82e-55	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
MHEPLEGL_01365	1.7e-314	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
MHEPLEGL_01366	2.47e-309	srrA1	-	-	G	ko:K02027,ko:K17244	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MHEPLEGL_01367	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MHEPLEGL_01368	9.1e-23	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
MHEPLEGL_01369	9.12e-135	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
MHEPLEGL_01370	9.17e-53	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
MHEPLEGL_01371	1.95e-94	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
MHEPLEGL_01372	7.75e-36	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
MHEPLEGL_01373	2.49e-70	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
MHEPLEGL_01374	1.89e-133	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
MHEPLEGL_01375	5.78e-67	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
MHEPLEGL_01377	1.15e-282	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MHEPLEGL_01378	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MHEPLEGL_01379	5.37e-250	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
MHEPLEGL_01380	1.14e-29	-	-	-	S	-	-	-	SLAP domain
MHEPLEGL_01381	3.07e-211	-	-	-	S	-	-	-	SLAP domain
MHEPLEGL_01382	1.98e-196	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
MHEPLEGL_01383	3.11e-28	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MHEPLEGL_01384	1.63e-62	-	-	-	-	-	-	-	-
MHEPLEGL_01385	2.89e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MHEPLEGL_01386	2.91e-230	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MHEPLEGL_01387	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MHEPLEGL_01388	2.42e-74	-	-	-	-	-	-	-	-
MHEPLEGL_01389	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MHEPLEGL_01390	5.15e-127	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
MHEPLEGL_01391	1.24e-187	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MHEPLEGL_01392	7.12e-111	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
MHEPLEGL_01393	5.67e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
MHEPLEGL_01394	3.89e-195	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MHEPLEGL_01395	4.52e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MHEPLEGL_01396	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MHEPLEGL_01397	1.3e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MHEPLEGL_01398	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MHEPLEGL_01399	3.09e-224	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MHEPLEGL_01400	5.23e-256	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MHEPLEGL_01401	1.19e-279	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
MHEPLEGL_01410	1.75e-225	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MHEPLEGL_01411	6.34e-126	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MHEPLEGL_01412	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MHEPLEGL_01413	2.46e-221	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MHEPLEGL_01414	1.06e-61	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MHEPLEGL_01415	1.25e-10	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MHEPLEGL_01416	1.72e-84	-	-	-	L	-	-	-	Helix-turn-helix domain
MHEPLEGL_01417	1.92e-206	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MHEPLEGL_01418	2.03e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
MHEPLEGL_01419	6.12e-90	ysdE	-	-	P	-	-	-	Citrate transporter
MHEPLEGL_01420	1.02e-119	ysdE	-	-	P	-	-	-	Citrate transporter
MHEPLEGL_01421	5.55e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
MHEPLEGL_01422	5.56e-21	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
MHEPLEGL_01423	9.69e-25	-	-	-	-	-	-	-	-
MHEPLEGL_01424	7.62e-122	-	-	-	-	-	-	-	-
MHEPLEGL_01425	4.54e-28	-	-	-	-	-	-	-	-
MHEPLEGL_01426	8.28e-308	-	-	-	L	-	-	-	Probable transposase
MHEPLEGL_01427	2.4e-44	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MHEPLEGL_01428	1.06e-57	-	-	-	-	-	-	-	-
MHEPLEGL_01429	1.5e-42	-	-	-	-	-	-	-	-
MHEPLEGL_01430	3.27e-53	-	-	-	-	-	-	-	-
MHEPLEGL_01431	4.18e-118	-	-	-	L	-	-	-	NUDIX domain
MHEPLEGL_01432	5.16e-218	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
MHEPLEGL_01433	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MHEPLEGL_01435	1.29e-140	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MHEPLEGL_01436	5.08e-134	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
MHEPLEGL_01437	1.11e-67	padR	-	-	K	-	-	-	Virulence activator alpha C-term
MHEPLEGL_01438	1.19e-38	-	-	-	L	-	-	-	Transposase
MHEPLEGL_01439	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
MHEPLEGL_01440	3.44e-202	lysR5	-	-	K	-	-	-	LysR substrate binding domain
MHEPLEGL_01441	1.32e-33	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
MHEPLEGL_01442	9.18e-58	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
MHEPLEGL_01443	3.28e-111	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
MHEPLEGL_01444	4.02e-17	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MHEPLEGL_01445	2.33e-139	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MHEPLEGL_01446	2.85e-86	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
MHEPLEGL_01447	1.33e-66	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
MHEPLEGL_01448	2.22e-125	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MHEPLEGL_01449	1.29e-279	-	-	-	S	-	-	-	Sterol carrier protein domain
MHEPLEGL_01450	7.88e-27	-	-	-	-	-	-	-	-
MHEPLEGL_01451	2.33e-136	-	-	-	K	-	-	-	LysR substrate binding domain
MHEPLEGL_01452	1.22e-218	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
MHEPLEGL_01453	0.0	-	-	-	S	-	-	-	membrane
MHEPLEGL_01454	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MHEPLEGL_01455	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MHEPLEGL_01456	3.12e-129	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MHEPLEGL_01457	4.62e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
MHEPLEGL_01458	7.03e-44	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
MHEPLEGL_01459	1.26e-91	yqhL	-	-	P	-	-	-	Rhodanese-like protein
MHEPLEGL_01460	2.89e-221	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MHEPLEGL_01461	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MHEPLEGL_01462	1.1e-161	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
MHEPLEGL_01463	1.25e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
MHEPLEGL_01464	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MHEPLEGL_01465	1.23e-173	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHEPLEGL_01466	1.32e-308	-	-	-	S	-	-	-	response to antibiotic
MHEPLEGL_01467	1.06e-161	-	-	-	-	-	-	-	-
MHEPLEGL_01468	3.38e-133	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MHEPLEGL_01469	4.75e-220	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MHEPLEGL_01470	7.94e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MHEPLEGL_01471	7.72e-313	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MHEPLEGL_01472	6.09e-43	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MHEPLEGL_01474	2.65e-123	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
MHEPLEGL_01475	1.78e-240	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MHEPLEGL_01476	1.19e-228	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MHEPLEGL_01477	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
MHEPLEGL_01479	1.47e-32	-	-	-	L	-	-	-	Transposase
MHEPLEGL_01480	3.83e-284	ycaM	-	-	E	-	-	-	amino acid
MHEPLEGL_01481	9.7e-188	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MHEPLEGL_01482	0.0	-	-	-	S	-	-	-	SH3-like domain
MHEPLEGL_01483	1.16e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MHEPLEGL_01484	8.23e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MHEPLEGL_01485	4.42e-248	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MHEPLEGL_01486	2.97e-211	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MHEPLEGL_01487	4.38e-108	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
MHEPLEGL_01488	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MHEPLEGL_01489	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MHEPLEGL_01490	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MHEPLEGL_01491	7.7e-80	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MHEPLEGL_01492	3.46e-241	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MHEPLEGL_01493	1.35e-201	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MHEPLEGL_01494	3.54e-230	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MHEPLEGL_01495	5.88e-44	-	-	-	-	-	-	-	-
MHEPLEGL_01496	3.57e-237	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MHEPLEGL_01497	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MHEPLEGL_01498	6.84e-121	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MHEPLEGL_01499	7.21e-173	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
MHEPLEGL_01500	5.21e-313	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
MHEPLEGL_01501	2.4e-152	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
MHEPLEGL_01502	2.26e-267	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
MHEPLEGL_01503	1.01e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MHEPLEGL_01504	2.66e-249	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MHEPLEGL_01505	4.26e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHEPLEGL_01506	2e-189	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
MHEPLEGL_01507	3.27e-170	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MHEPLEGL_01508	2.62e-301	ymfH	-	-	S	-	-	-	Peptidase M16
MHEPLEGL_01509	3.62e-289	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
MHEPLEGL_01510	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MHEPLEGL_01511	4.46e-90	WQ51_03320	-	-	S	-	-	-	Protein of unknown function (DUF1149)
MHEPLEGL_01512	1.49e-136	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MHEPLEGL_01513	8.55e-270	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
MHEPLEGL_01514	4.91e-37	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
MHEPLEGL_01515	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
MHEPLEGL_01516	1.5e-257	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
MHEPLEGL_01517	1.48e-151	-	-	-	S	-	-	-	SNARE associated Golgi protein
MHEPLEGL_01518	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MHEPLEGL_01519	8.64e-40	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MHEPLEGL_01520	4.97e-218	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MHEPLEGL_01521	2.07e-196	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MHEPLEGL_01522	4.88e-147	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
MHEPLEGL_01523	4.03e-143	-	-	-	S	-	-	-	CYTH
MHEPLEGL_01524	3.88e-146	yjbH	-	-	Q	-	-	-	Thioredoxin
MHEPLEGL_01525	7.91e-206	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MHEPLEGL_01526	5.25e-178	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MHEPLEGL_01527	1.54e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MHEPLEGL_01528	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MHEPLEGL_01529	1.83e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
MHEPLEGL_01530	4.33e-36	-	-	-	-	-	-	-	-
MHEPLEGL_01531	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHEPLEGL_01532	4.65e-189	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
MHEPLEGL_01533	1.05e-112	-	-	-	-	-	-	-	-
MHEPLEGL_01534	2.6e-96	-	-	-	-	-	-	-	-
MHEPLEGL_01535	1.78e-207	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
MHEPLEGL_01536	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MHEPLEGL_01537	4.17e-60	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
MHEPLEGL_01538	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MHEPLEGL_01539	3.74e-115	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MHEPLEGL_01540	2.88e-221	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
MHEPLEGL_01541	1.02e-78	-	-	-	-	-	-	-	-
MHEPLEGL_01542	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MHEPLEGL_01543	7.07e-97	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MHEPLEGL_01544	3.01e-312	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MHEPLEGL_01545	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MHEPLEGL_01546	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MHEPLEGL_01547	4.52e-140	vanZ	-	-	V	-	-	-	VanZ like family
MHEPLEGL_01548	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MHEPLEGL_01549	2.92e-38	-	-	-	EGP	-	-	-	Major Facilitator
MHEPLEGL_01550	3.79e-131	-	-	-	EGP	-	-	-	Major Facilitator
MHEPLEGL_01551	1.99e-18	-	-	-	EGP	-	-	-	Major Facilitator
MHEPLEGL_01552	7.49e-303	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MHEPLEGL_01553	2.59e-21	-	-	-	-	-	-	-	-
MHEPLEGL_01554	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MHEPLEGL_01555	1.74e-154	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
MHEPLEGL_01556	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MHEPLEGL_01557	2.41e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MHEPLEGL_01558	1.12e-215	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MHEPLEGL_01559	6.76e-101	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
MHEPLEGL_01560	2.25e-31	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
MHEPLEGL_01561	1.7e-171	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MHEPLEGL_01562	6.29e-291	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
MHEPLEGL_01563	3.94e-144	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MHEPLEGL_01564	5.59e-249	-	-	-	D	-	-	-	nuclear chromosome segregation
MHEPLEGL_01565	1.5e-109	-	-	-	M	-	-	-	LysM domain protein
MHEPLEGL_01566	5.26e-19	-	-	-	-	-	-	-	-
MHEPLEGL_01567	4.4e-31	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
MHEPLEGL_01568	1.63e-61	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
MHEPLEGL_01569	2.07e-37	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
MHEPLEGL_01570	3.7e-45	-	-	-	-	-	-	-	-
MHEPLEGL_01571	2.87e-22	-	-	-	-	-	-	-	-
MHEPLEGL_01572	1.52e-43	-	-	-	-	-	-	-	-
MHEPLEGL_01573	4.09e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
MHEPLEGL_01574	1.42e-170	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
MHEPLEGL_01575	5.17e-83	-	-	-	S	-	-	-	Enterocin A Immunity
MHEPLEGL_01576	8.76e-73	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MHEPLEGL_01577	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
MHEPLEGL_01578	1.29e-105	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
MHEPLEGL_01579	7.78e-300	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MHEPLEGL_01580	1.72e-305	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
MHEPLEGL_01581	3.69e-187	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
MHEPLEGL_01582	7.71e-212	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
MHEPLEGL_01583	4.36e-155	-	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
MHEPLEGL_01584	6.62e-94	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
MHEPLEGL_01585	1.92e-125	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHEPLEGL_01586	7.89e-126	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHEPLEGL_01587	3.88e-151	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
MHEPLEGL_01588	6.92e-304	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHEPLEGL_01589	1.59e-172	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
MHEPLEGL_01590	9.45e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MHEPLEGL_01591	3.8e-204	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MHEPLEGL_01592	2.66e-57	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
MHEPLEGL_01593	3.88e-301	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
MHEPLEGL_01594	1.36e-167	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
MHEPLEGL_01595	1.34e-145	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHEPLEGL_01596	1.17e-38	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
MHEPLEGL_01598	5.23e-45	-	-	-	-	-	-	-	-
MHEPLEGL_01600	2.28e-157	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
MHEPLEGL_01601	9.5e-304	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
MHEPLEGL_01602	5.32e-35	-	-	-	S	-	-	-	Transglycosylase associated protein
MHEPLEGL_01603	0.000255	-	-	-	S	-	-	-	CsbD-like
MHEPLEGL_01604	4.24e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
MHEPLEGL_01605	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
MHEPLEGL_01606	1.32e-34	-	-	-	-	-	-	-	-
MHEPLEGL_01607	2.98e-185	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MHEPLEGL_01608	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MHEPLEGL_01609	1.17e-51	-	-	-	-	-	-	-	-
MHEPLEGL_01611	4.54e-40	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MHEPLEGL_01612	3.52e-79	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MHEPLEGL_01613	1.9e-65	-	-	-	-	-	-	-	-
MHEPLEGL_01614	1.59e-96	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MHEPLEGL_01615	1.01e-59	-	-	-	-	-	-	-	-
MHEPLEGL_01616	5.98e-105	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MHEPLEGL_01617	1.03e-190	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
MHEPLEGL_01618	9.76e-36	-	-	-	S	-	-	-	MazG-like family
MHEPLEGL_01619	1.13e-75	-	-	-	-	-	-	-	-
MHEPLEGL_01620	7.55e-58	-	-	-	-	ko:K07473	-	ko00000,ko02048	-
MHEPLEGL_01621	8.52e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF3923)
MHEPLEGL_01622	1.69e-65	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
MHEPLEGL_01623	1.64e-181	yxaM	-	-	EGP	-	-	-	Major facilitator Superfamily
MHEPLEGL_01624	2.16e-30	codA	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
MHEPLEGL_01625	3.73e-44	cdd	2.4.2.4, 3.5.4.5	-	F	ko:K00758,ko:K01489	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	ko00000,ko00001,ko01000	cytidine deaminase activity
MHEPLEGL_01626	2.64e-119	-	-	-	S	-	-	-	AAA domain
MHEPLEGL_01627	2.92e-192	-	-	-	M	-	-	-	Phosphotransferase enzyme family
MHEPLEGL_01628	1.02e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
MHEPLEGL_01629	1.39e-181	-	-	-	F	-	-	-	Phosphorylase superfamily
MHEPLEGL_01630	1.15e-150	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
MHEPLEGL_01631	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MHEPLEGL_01632	7.06e-30	-	-	-	-	-	-	-	-
MHEPLEGL_01633	6.33e-87	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MHEPLEGL_01634	5.22e-229	lipA	-	-	I	-	-	-	Carboxylesterase family
MHEPLEGL_01636	9.3e-273	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MHEPLEGL_01637	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
MHEPLEGL_01638	4.18e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
MHEPLEGL_01639	1.11e-164	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MHEPLEGL_01640	1.97e-257	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MHEPLEGL_01641	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
MHEPLEGL_01642	6.82e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MHEPLEGL_01643	1.6e-63	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MHEPLEGL_01644	6.96e-263	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MHEPLEGL_01645	1.04e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MHEPLEGL_01646	6.6e-91	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
MHEPLEGL_01647	1.28e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MHEPLEGL_01648	1.34e-198	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MHEPLEGL_01649	6.51e-250	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHEPLEGL_01650	4.4e-47	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHEPLEGL_01651	7.83e-206	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MHEPLEGL_01652	4.88e-195	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
MHEPLEGL_01653	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MHEPLEGL_01654	3.93e-28	-	-	-	S	-	-	-	ASCH
MHEPLEGL_01655	6.84e-57	-	-	-	S	-	-	-	ASCH
MHEPLEGL_01656	1.46e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MHEPLEGL_01657	1.67e-46	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MHEPLEGL_01658	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHEPLEGL_01659	4.78e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MHEPLEGL_01660	4.49e-315	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MHEPLEGL_01661	2.32e-189	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MHEPLEGL_01662	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MHEPLEGL_01663	2.26e-213	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MHEPLEGL_01664	2.51e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MHEPLEGL_01665	8.07e-164	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MHEPLEGL_01666	9.72e-43	-	-	-	-	-	-	-	-
MHEPLEGL_01667	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MHEPLEGL_01668	1.67e-74	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
MHEPLEGL_01669	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
MHEPLEGL_01670	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MHEPLEGL_01671	3.69e-233	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MHEPLEGL_01672	5.34e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHEPLEGL_01673	6.3e-251	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHEPLEGL_01674	3.56e-233	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHEPLEGL_01675	7.39e-226	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MHEPLEGL_01676	3.53e-203	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHEPLEGL_01677	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MHEPLEGL_01678	2.46e-80	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	efflux transmembrane transporter activity
MHEPLEGL_01679	1e-28	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MHEPLEGL_01680	2.22e-133	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MHEPLEGL_01681	1.1e-57	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MHEPLEGL_01682	2.66e-57	-	-	-	S	-	-	-	Enterocin A Immunity
MHEPLEGL_01683	1.45e-54	-	-	-	S	-	-	-	Fic/DOC family
MHEPLEGL_01684	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MHEPLEGL_01685	9.25e-288	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MHEPLEGL_01686	1.85e-30	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
MHEPLEGL_01687	2.65e-247	-	-	-	S	-	-	-	Bacteriocin helveticin-J
MHEPLEGL_01688	0.0	-	-	-	M	-	-	-	Peptidase family M1 domain
MHEPLEGL_01689	2.04e-226	-	-	-	S	-	-	-	SLAP domain
MHEPLEGL_01690	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MHEPLEGL_01691	0.000234	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
MHEPLEGL_01693	9.42e-122	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MHEPLEGL_01694	2.22e-30	-	-	-	-	-	-	-	-
MHEPLEGL_01695	1.89e-133	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
MHEPLEGL_01696	8.9e-51	-	-	-	-	-	-	-	-
MHEPLEGL_01697	2.19e-69	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
MHEPLEGL_01698	6.72e-115	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
MHEPLEGL_01699	2.03e-73	-	-	-	-	-	-	-	-
MHEPLEGL_01700	3.49e-313	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MHEPLEGL_01701	1.3e-28	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MHEPLEGL_01702	2.23e-53	-	-	-	G	-	-	-	MFS/sugar transport protein
MHEPLEGL_01703	2.95e-83	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MHEPLEGL_01704	2.4e-76	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MHEPLEGL_01705	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MHEPLEGL_01706	4.28e-99	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
MHEPLEGL_01707	4.58e-117	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
MHEPLEGL_01708	5.76e-290	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MHEPLEGL_01709	7.99e-164	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
MHEPLEGL_01712	3.85e-62	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MHEPLEGL_01713	2.06e-181	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
MHEPLEGL_01714	3.9e-79	-	-	-	-	-	-	-	-
MHEPLEGL_01715	2.57e-20	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
MHEPLEGL_01716	2.5e-26	ynbB	-	-	P	-	-	-	aluminum resistance
MHEPLEGL_01717	4.6e-78	ynbB	-	-	P	-	-	-	aluminum resistance
MHEPLEGL_01718	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MHEPLEGL_01719	5.01e-157	-	-	-	-	-	-	-	-
MHEPLEGL_01720	1.93e-212	-	-	-	-	-	-	-	-
MHEPLEGL_01721	1.64e-204	-	-	-	-	-	-	-	-
MHEPLEGL_01722	8.09e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MHEPLEGL_01723	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHEPLEGL_01724	3.59e-264	-	-	-	M	-	-	-	Glycosyl transferases group 1
MHEPLEGL_01725	1.69e-172	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MHEPLEGL_01726	1.07e-111	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MHEPLEGL_01727	9.54e-74	-	-	-	-	-	-	-	-
MHEPLEGL_01728	0.0	-	-	-	S	-	-	-	ABC transporter
MHEPLEGL_01729	2.79e-178	-	-	-	S	-	-	-	Putative threonine/serine exporter
MHEPLEGL_01730	8.95e-110	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
MHEPLEGL_01731	1.22e-172	-	-	-	S	-	-	-	Peptidase_C39 like family
MHEPLEGL_01732	6.23e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MHEPLEGL_01733	3.88e-241	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
MHEPLEGL_01734	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
MHEPLEGL_01735	8.12e-238	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MHEPLEGL_01736	1.78e-277	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MHEPLEGL_01737	9.85e-199	-	-	-	S	-	-	-	reductase
MHEPLEGL_01738	1e-106	yxeH	-	-	S	-	-	-	hydrolase
MHEPLEGL_01739	6.74e-57	yxeH	-	-	S	-	-	-	hydrolase
MHEPLEGL_01740	9.09e-20	gyaR	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHEPLEGL_01741	5.4e-99	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHEPLEGL_01742	1.35e-54	gyaR	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHEPLEGL_01743	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
MHEPLEGL_01744	1.73e-40	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
MHEPLEGL_01745	1.65e-37	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
MHEPLEGL_01746	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MHEPLEGL_01747	1.55e-308	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MHEPLEGL_01748	0.0	oatA	-	-	I	-	-	-	Acyltransferase
MHEPLEGL_01749	1.05e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MHEPLEGL_01750	4.13e-184	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MHEPLEGL_01751	6.62e-48	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
MHEPLEGL_01752	3.62e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MHEPLEGL_01753	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MHEPLEGL_01754	9.47e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MHEPLEGL_01755	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MHEPLEGL_01756	9.45e-234	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MHEPLEGL_01757	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MHEPLEGL_01758	4.41e-216	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
MHEPLEGL_01759	1.48e-216	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
MHEPLEGL_01760	1.62e-80	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHEPLEGL_01761	1.74e-167	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MHEPLEGL_01762	2.85e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MHEPLEGL_01763	1.1e-166	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MHEPLEGL_01764	6.98e-145	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MHEPLEGL_01765	1.03e-57	-	-	-	M	-	-	-	Lysin motif
MHEPLEGL_01766	1.81e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MHEPLEGL_01767	1.09e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MHEPLEGL_01768	7.41e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MHEPLEGL_01769	8.21e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MHEPLEGL_01770	3.15e-296	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
MHEPLEGL_01771	3.57e-205	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHEPLEGL_01772	1.26e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MHEPLEGL_01773	9.98e-150	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
MHEPLEGL_01774	2.03e-191	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
MHEPLEGL_01775	9.85e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MHEPLEGL_01776	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MHEPLEGL_01777	2.73e-203	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MHEPLEGL_01778	5.41e-173	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHEPLEGL_01779	8.1e-200	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
MHEPLEGL_01780	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHEPLEGL_01781	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MHEPLEGL_01782	9.64e-218	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
MHEPLEGL_01783	5.68e-117	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MHEPLEGL_01784	3.83e-312	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MHEPLEGL_01785	5.21e-225	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MHEPLEGL_01786	1.24e-154	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MHEPLEGL_01787	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MHEPLEGL_01788	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MHEPLEGL_01789	1.91e-54	-	-	-	-	-	-	-	-
MHEPLEGL_01790	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MHEPLEGL_01791	8.3e-21	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MHEPLEGL_01793	1.38e-121	-	-	-	S	-	-	-	SLAP domain
MHEPLEGL_01794	4.08e-69	-	-	-	S	-	-	-	SLAP domain
MHEPLEGL_01795	2.34e-28	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
MHEPLEGL_01796	7.01e-25	-	-	-	-	-	-	-	-
MHEPLEGL_01797	2.68e-264	-	-	-	G	-	-	-	Major Facilitator Superfamily
MHEPLEGL_01799	4.12e-24	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
MHEPLEGL_01800	4.61e-57	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
MHEPLEGL_01801	9.63e-14	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
MHEPLEGL_01802	1.5e-72	-	-	-	-	-	-	-	-
MHEPLEGL_01805	4.98e-273	-	-	-	-	-	-	-	-
MHEPLEGL_01806	4.41e-158	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
MHEPLEGL_01807	4.14e-81	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
MHEPLEGL_01809	1.44e-226	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MHEPLEGL_01812	1.06e-279	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MHEPLEGL_01813	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
MHEPLEGL_01814	7.31e-86	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MHEPLEGL_01815	2.54e-38	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
MHEPLEGL_01816	2.27e-116	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
MHEPLEGL_01817	2.68e-123	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
MHEPLEGL_01818	9.67e-37	-	-	-	-	-	-	-	-
MHEPLEGL_01819	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
MHEPLEGL_01820	2.25e-133	-	-	-	-	-	-	-	-
MHEPLEGL_01821	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MHEPLEGL_01822	4.9e-100	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MHEPLEGL_01823	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MHEPLEGL_01824	1.84e-188	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MHEPLEGL_01825	3.04e-206	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MHEPLEGL_01826	5.39e-102	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MHEPLEGL_01827	9.84e-195	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MHEPLEGL_01829	1.57e-170	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
MHEPLEGL_01830	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
MHEPLEGL_01831	1.3e-205	-	-	-	S	-	-	-	Phospholipase, patatin family
MHEPLEGL_01834	1.76e-109	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
MHEPLEGL_01835	6.09e-162	-	-	-	F	-	-	-	NUDIX domain
MHEPLEGL_01836	4.15e-172	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
MHEPLEGL_01837	7.57e-77	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHEPLEGL_01838	2.8e-124	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
MHEPLEGL_01839	1.74e-190	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MHEPLEGL_01840	2.12e-228	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
MHEPLEGL_01841	7.82e-147	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
MHEPLEGL_01842	1.29e-163	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MHEPLEGL_01843	7.9e-306	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MHEPLEGL_01844	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MHEPLEGL_01845	9.76e-74	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MHEPLEGL_01846	5.59e-220	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	Glycosyltransferase like family 2
MHEPLEGL_01847	1.2e-87	-	-	-	S	-	-	-	GtrA-like protein
MHEPLEGL_01848	7.94e-176	-	-	-	C	-	-	-	Glycerophosphoryl diester phosphodiesterase family
MHEPLEGL_01849	1.28e-68	-	-	-	C	-	-	-	Glycerophosphoryl diester phosphodiesterase family
MHEPLEGL_01850	3.07e-32	-	-	-	-	-	-	-	-
MHEPLEGL_01851	3.56e-216	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MHEPLEGL_01852	9.23e-48	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MHEPLEGL_01853	5.9e-71	-	-	-	-	-	-	-	-
MHEPLEGL_01854	3.15e-53	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MHEPLEGL_01855	4.46e-165	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MHEPLEGL_01856	1.97e-20	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MHEPLEGL_01857	7.8e-49	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
MHEPLEGL_01858	5.52e-36	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
MHEPLEGL_01859	1.9e-190	-	-	-	-	-	-	-	-
MHEPLEGL_01861	4.35e-173	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MHEPLEGL_01862	2.5e-192	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MHEPLEGL_01863	6.97e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF3232)
MHEPLEGL_01864	3.79e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MHEPLEGL_01865	1.57e-279	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MHEPLEGL_01866	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MHEPLEGL_01867	1.52e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MHEPLEGL_01868	1.83e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MHEPLEGL_01869	3.94e-308	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MHEPLEGL_01870	9.14e-55	-	-	-	-	-	-	-	-
MHEPLEGL_01871	1.91e-103	uspA	-	-	T	-	-	-	universal stress protein
MHEPLEGL_01872	8.71e-278	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MHEPLEGL_01873	8.85e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
MHEPLEGL_01874	1.12e-68	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
MHEPLEGL_01875	1.75e-229	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
MHEPLEGL_01876	4.22e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
MHEPLEGL_01877	4.24e-94	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MHEPLEGL_01878	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MHEPLEGL_01879	6.03e-221	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MHEPLEGL_01880	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MHEPLEGL_01881	4.8e-122	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHEPLEGL_01882	2.63e-90	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MHEPLEGL_01883	3.07e-39	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHEPLEGL_01884	2.91e-166	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MHEPLEGL_01885	1.3e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MHEPLEGL_01886	4.37e-241	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MHEPLEGL_01887	1.25e-202	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MHEPLEGL_01888	5.18e-234	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MHEPLEGL_01889	1.21e-146	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MHEPLEGL_01890	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
MHEPLEGL_01893	3e-250	ampC	-	-	V	-	-	-	Beta-lactamase
MHEPLEGL_01895	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MHEPLEGL_01897	3.47e-20	-	-	-	-	-	-	-	-
MHEPLEGL_01898	9.54e-241	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
MHEPLEGL_01899	3.29e-52	-	-	-	-	-	-	-	-
MHEPLEGL_01900	2.2e-280	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHEPLEGL_01901	2.03e-41	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHEPLEGL_01902	7.61e-111	-	3.4.21.96	-	S	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	SLAP domain
MHEPLEGL_01905	1.22e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MHEPLEGL_01906	9.39e-295	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MHEPLEGL_01907	2.54e-142	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MHEPLEGL_01908	3.71e-145	-	-	-	S	-	-	-	YSIRK type signal peptide
MHEPLEGL_01909	1.07e-78	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MHEPLEGL_01911	3.63e-91	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MHEPLEGL_01912	2.92e-190	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MHEPLEGL_01913	1.25e-147	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MHEPLEGL_01914	6.73e-197	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
MHEPLEGL_01916	6.9e-298	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MHEPLEGL_01917	1.22e-307	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter