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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
COEAHMKE_00001	1.37e-94	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
COEAHMKE_00003	1.05e-162	-	-	-	F	-	-	-	NUDIX domain
COEAHMKE_00004	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COEAHMKE_00005	1.97e-140	pncA	-	-	Q	-	-	-	Isochorismatase family
COEAHMKE_00006	8.72e-66	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
COEAHMKE_00007	1.08e-181	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
COEAHMKE_00009	2.72e-149	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA domain
COEAHMKE_00010	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
COEAHMKE_00011	1.08e-216	ydhF	-	-	S	-	-	-	Aldo keto reductase
COEAHMKE_00012	3.25e-224	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
COEAHMKE_00013	6.38e-108	-	-	-	-	-	-	-	-
COEAHMKE_00014	8.69e-49	-	-	-	C	-	-	-	FMN_bind
COEAHMKE_00015	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
COEAHMKE_00016	4e-140	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
COEAHMKE_00017	6.7e-264	pbpX1	-	-	V	-	-	-	Beta-lactamase
COEAHMKE_00018	1.01e-251	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
COEAHMKE_00019	1.74e-271	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
COEAHMKE_00020	1.56e-181	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
COEAHMKE_00021	3.65e-222	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
COEAHMKE_00022	3.29e-280	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
COEAHMKE_00023	2.94e-108	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
COEAHMKE_00024	1.9e-316	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
COEAHMKE_00025	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
COEAHMKE_00026	2.34e-241	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
COEAHMKE_00027	0.0	potE	-	-	E	-	-	-	Amino Acid
COEAHMKE_00028	1.07e-134	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
COEAHMKE_00029	1.1e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
COEAHMKE_00030	5.53e-276	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
COEAHMKE_00031	5.52e-285	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
COEAHMKE_00032	3.27e-192	-	-	-	-	-	-	-	-
COEAHMKE_00033	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COEAHMKE_00034	1.48e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
COEAHMKE_00035	4.42e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
COEAHMKE_00036	2.46e-224	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
COEAHMKE_00037	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
COEAHMKE_00038	1.63e-128	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
COEAHMKE_00039	6.48e-244	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
COEAHMKE_00040	6.77e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
COEAHMKE_00041	2.48e-124	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
COEAHMKE_00042	1.72e-71	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
COEAHMKE_00043	2.72e-263	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
COEAHMKE_00044	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
COEAHMKE_00045	5.41e-129	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
COEAHMKE_00046	9e-46	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
COEAHMKE_00047	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COEAHMKE_00048	1.03e-34	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
COEAHMKE_00049	1.96e-136	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
COEAHMKE_00050	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
COEAHMKE_00051	1.38e-139	-	-	-	S	-	-	-	repeat protein
COEAHMKE_00052	3.18e-161	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
COEAHMKE_00053	1.56e-278	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
COEAHMKE_00054	4.07e-74	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
COEAHMKE_00055	1.33e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
COEAHMKE_00056	3.97e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
COEAHMKE_00057	1.28e-56	-	-	-	-	-	-	-	-
COEAHMKE_00058	6.29e-135	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
COEAHMKE_00059	1.15e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
COEAHMKE_00060	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
COEAHMKE_00061	3.52e-150	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
COEAHMKE_00062	3.29e-191	ylmH	-	-	S	-	-	-	S4 domain protein
COEAHMKE_00063	5.07e-62	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
COEAHMKE_00064	1.26e-95	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
COEAHMKE_00065	1.93e-262	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
COEAHMKE_00066	2.46e-305	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
COEAHMKE_00067	1.15e-180	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
COEAHMKE_00068	4.23e-268	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
COEAHMKE_00069	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
COEAHMKE_00070	3.96e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
COEAHMKE_00071	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
COEAHMKE_00072	8.94e-70	ftsL	-	-	D	-	-	-	Cell division protein FtsL
COEAHMKE_00073	4.87e-234	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
COEAHMKE_00074	3.81e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
COEAHMKE_00075	4.46e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
COEAHMKE_00076	1.09e-18	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
COEAHMKE_00077	8.04e-124	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
COEAHMKE_00078	1.67e-188	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
COEAHMKE_00079	1.01e-226	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
COEAHMKE_00080	3.32e-148	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
COEAHMKE_00081	4.33e-162	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
COEAHMKE_00082	8.83e-303	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
COEAHMKE_00083	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
COEAHMKE_00084	7.85e-125	-	-	-	-	ko:K19167	-	ko00000,ko02048	-
COEAHMKE_00085	1.13e-114	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
COEAHMKE_00086	4.49e-150	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
COEAHMKE_00087	1.54e-17	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
COEAHMKE_00088	4.4e-217	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	Glycosyltransferase like family 2
COEAHMKE_00089	8.41e-88	-	-	-	S	-	-	-	GtrA-like protein
COEAHMKE_00090	8.21e-269	-	-	-	C	-	-	-	Glycerophosphoryl diester phosphodiesterase family
COEAHMKE_00091	3.07e-32	-	-	-	-	-	-	-	-
COEAHMKE_00092	4.77e-111	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
COEAHMKE_00093	2.23e-73	-	-	-	K	-	-	-	Helix-turn-helix domain
COEAHMKE_00094	5.37e-143	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COEAHMKE_00095	3e-221	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
COEAHMKE_00096	3.52e-219	-	-	-	K	-	-	-	Transcriptional regulator
COEAHMKE_00097	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COEAHMKE_00098	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COEAHMKE_00099	1.45e-138	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
COEAHMKE_00100	0.0	snf	-	-	KL	-	-	-	domain protein
COEAHMKE_00101	2.89e-50	snf	-	-	KL	-	-	-	domain protein
COEAHMKE_00102	3.72e-22	snf	-	-	KL	-	-	-	domain protein
COEAHMKE_00103	8.57e-43	-	-	-	-	-	-	-	-
COEAHMKE_00104	2.07e-24	-	-	-	-	-	-	-	-
COEAHMKE_00105	9.82e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
COEAHMKE_00106	2.62e-121	-	-	-	K	-	-	-	acetyltransferase
COEAHMKE_00107	7.02e-212	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
COEAHMKE_00108	4.16e-62	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
COEAHMKE_00109	1.63e-48	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
COEAHMKE_00110	6.75e-138	-	-	-	K	ko:K09705	-	ko00000	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
COEAHMKE_00111	4.8e-109	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
COEAHMKE_00112	9.45e-62	-	1.1.1.3	-	T	ko:K00003,ko:K07166	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	phosphoserine phosphatase activity
COEAHMKE_00113	2.82e-185	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
COEAHMKE_00114	3.33e-49	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
COEAHMKE_00115	4.38e-76	-	-	-	S	-	-	-	Alpha beta hydrolase
COEAHMKE_00116	1.48e-67	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
COEAHMKE_00117	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
COEAHMKE_00119	1.36e-151	-	-	-	L	-	-	-	Integrase
COEAHMKE_00121	3.81e-125	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
COEAHMKE_00122	6.18e-159	-	-	-	L	-	-	-	Helix-turn-helix domain
COEAHMKE_00123	2.08e-204	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
COEAHMKE_00124	1.89e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
COEAHMKE_00125	2.95e-139	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
COEAHMKE_00126	1.32e-144	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
COEAHMKE_00127	1.03e-91	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
COEAHMKE_00128	5.45e-37	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
COEAHMKE_00129	9.52e-141	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
COEAHMKE_00130	2.61e-133	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
COEAHMKE_00131	6.71e-161	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
COEAHMKE_00133	8.81e-82	-	-	-	S	-	-	-	Abi-like protein
COEAHMKE_00134	8.62e-109	kptA	-	-	H	ko:K07559	-	ko00000,ko01000,ko03016	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
COEAHMKE_00135	4.58e-87	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
COEAHMKE_00136	7.55e-44	-	-	-	-	-	-	-	-
COEAHMKE_00137	3.01e-292	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
COEAHMKE_00138	3.37e-190	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
COEAHMKE_00139	8.01e-68	-	-	-	-	-	-	-	-
COEAHMKE_00140	1.44e-31	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
COEAHMKE_00141	1.35e-161	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
COEAHMKE_00142	9.61e-56	-	-	-	-	-	-	-	-
COEAHMKE_00143	3.64e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
COEAHMKE_00144	4.34e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
COEAHMKE_00145	1.37e-115	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
COEAHMKE_00146	7.77e-34	-	-	-	K	-	-	-	Helix-turn-helix domain
COEAHMKE_00147	3.86e-261	-	-	-	S	-	-	-	Bacteriocin helveticin-J
COEAHMKE_00148	5.42e-310	slpX	-	-	S	-	-	-	SLAP domain
COEAHMKE_00149	3.99e-74	-	-	-	L	-	-	-	Integrase
COEAHMKE_00150	4.36e-162	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
COEAHMKE_00151	6.36e-161	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
COEAHMKE_00152	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
COEAHMKE_00153	3.67e-58	-	-	-	-	-	-	-	-
COEAHMKE_00154	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	DEAD/DEAH box helicase
COEAHMKE_00155	1.6e-296	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
COEAHMKE_00156	1.38e-116	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
COEAHMKE_00157	1.58e-172	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
COEAHMKE_00158	1.57e-80	-	-	-	M	-	-	-	Glycosyltransferase like family 2
COEAHMKE_00160	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
COEAHMKE_00161	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
COEAHMKE_00162	6.33e-293	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
COEAHMKE_00163	4.43e-32	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
COEAHMKE_00164	3.49e-108	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
COEAHMKE_00165	4.19e-13	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
COEAHMKE_00166	7.64e-247	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
COEAHMKE_00167	7.67e-234	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
COEAHMKE_00168	2.19e-124	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
COEAHMKE_00169	2.6e-112	-	-	-	L	-	-	-	Resolvase, N terminal domain
COEAHMKE_00170	1.1e-199	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
COEAHMKE_00171	6.47e-14	-	-	-	-	-	-	-	-
COEAHMKE_00172	4.42e-187	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
COEAHMKE_00173	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
COEAHMKE_00174	7.93e-289	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
COEAHMKE_00175	1.61e-118	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
COEAHMKE_00176	7.22e-133	-	-	-	L	-	-	-	HTH-like domain
COEAHMKE_00177	8.45e-92	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
COEAHMKE_00178	3.62e-246	pbpX1	-	-	V	-	-	-	Beta-lactamase
COEAHMKE_00179	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
COEAHMKE_00180	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
COEAHMKE_00181	1.25e-204	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
COEAHMKE_00182	3.94e-117	-	-	-	G	-	-	-	Phosphotransferase enzyme family
COEAHMKE_00183	1.19e-85	-	-	-	G	-	-	-	Phosphotransferase enzyme family
COEAHMKE_00184	7.58e-244	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COEAHMKE_00185	3.62e-73	-	-	-	-	-	-	-	-
COEAHMKE_00186	9.04e-67	-	-	-	-	-	-	-	-
COEAHMKE_00187	0.0	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
COEAHMKE_00188	1.29e-196	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	haloacid dehalogenase-like hydrolase
COEAHMKE_00189	0.0	fusA1	-	-	J	-	-	-	elongation factor G
COEAHMKE_00190	3.49e-210	yvgN	-	-	C	-	-	-	Aldo keto reductase
COEAHMKE_00191	6.52e-270	-	-	-	S	-	-	-	SLAP domain
COEAHMKE_00192	6.05e-19	-	-	-	S	-	-	-	Bacteriocin helveticin-J
COEAHMKE_00193	1.4e-172	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
COEAHMKE_00194	2.21e-228	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
COEAHMKE_00195	9.6e-168	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
COEAHMKE_00196	4.47e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COEAHMKE_00197	4.85e-68	-	-	-	-	-	-	-	-
COEAHMKE_00198	1.73e-24	-	-	-	-	-	-	-	-
COEAHMKE_00199	1.67e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
COEAHMKE_00200	3.46e-223	ydbI	-	-	K	-	-	-	AI-2E family transporter
COEAHMKE_00201	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
COEAHMKE_00202	4.63e-78	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
COEAHMKE_00203	6.12e-112	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
COEAHMKE_00204	3.65e-128	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
COEAHMKE_00205	5.71e-192	-	-	-	S	-	-	-	Putative ABC-transporter type IV
COEAHMKE_00206	3.64e-307	-	-	-	S	-	-	-	LPXTG cell wall anchor motif
COEAHMKE_00207	1.59e-73	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
COEAHMKE_00208	6.5e-63	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	DNA mismatch endonuclease Vsr
COEAHMKE_00209	6.65e-186	dcm	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
COEAHMKE_00210	3.87e-261	-	-	-	V	-	-	-	Z1 domain
COEAHMKE_00211	3.46e-129	-	-	-	L	-	-	-	NgoFVII restriction endonuclease
COEAHMKE_00212	8.53e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
COEAHMKE_00213	5.09e-28	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
COEAHMKE_00214	1.96e-192	-	-	-	K	ko:K09705	-	ko00000	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
COEAHMKE_00216	5.02e-81	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
COEAHMKE_00218	1.65e-208	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
COEAHMKE_00219	7.7e-265	-	-	-	EGP	-	-	-	Major facilitator Superfamily
COEAHMKE_00220	3.49e-10	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
COEAHMKE_00221	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
COEAHMKE_00222	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
COEAHMKE_00223	3.55e-173	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
COEAHMKE_00224	6.71e-78	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COEAHMKE_00225	3e-308	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
COEAHMKE_00226	1.74e-142	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
COEAHMKE_00227	1.13e-182	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
COEAHMKE_00229	8.45e-223	repA	-	-	S	-	-	-	Replication initiator protein A
COEAHMKE_00230	4.18e-151	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
COEAHMKE_00231	3.55e-162	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
COEAHMKE_00232	2.26e-63	-	-	-	V	-	-	-	ABC transporter transmembrane region
COEAHMKE_00233	1.23e-95	-	-	-	KLT	-	-	-	serine threonine protein kinase
COEAHMKE_00234	9.26e-135	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
COEAHMKE_00235	1.44e-52	-	-	-	K	-	-	-	LysR substrate binding domain
COEAHMKE_00236	4.52e-127	-	-	-	K	-	-	-	LysR substrate binding domain
COEAHMKE_00237	2.2e-141	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
COEAHMKE_00238	5.04e-47	-	-	-	S	-	-	-	Cytochrome b5
COEAHMKE_00239	4.4e-212	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
COEAHMKE_00240	1.06e-207	-	-	-	M	-	-	-	Glycosyl transferase family 8
COEAHMKE_00241	1.4e-234	-	-	-	M	-	-	-	Glycosyl transferase family 8
COEAHMKE_00242	7.53e-203	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
COEAHMKE_00243	1.46e-53	-	-	-	K	-	-	-	Helix-turn-helix domain
COEAHMKE_00244	2.05e-112	-	-	-	K	-	-	-	Helix-turn-helix domain
COEAHMKE_00245	8.43e-19	-	-	-	-	-	-	-	-
COEAHMKE_00246	2.49e-87	-	-	-	-	-	-	-	-
COEAHMKE_00247	1.25e-188	-	-	-	I	-	-	-	Acyl-transferase
COEAHMKE_00248	8e-255	-	-	-	S	-	-	-	SLAP domain
COEAHMKE_00249	1.01e-170	-	-	-	-	-	-	-	-
COEAHMKE_00250	8.48e-214	-	-	-	S	-	-	-	SLAP domain
COEAHMKE_00253	2.21e-46	-	-	-	-	-	-	-	-
COEAHMKE_00255	2.8e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
COEAHMKE_00256	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
COEAHMKE_00257	8.07e-314	yycH	-	-	S	-	-	-	YycH protein
COEAHMKE_00258	1.18e-188	yycI	-	-	S	-	-	-	YycH protein
COEAHMKE_00259	6.89e-188	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
COEAHMKE_00260	1.01e-275	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
COEAHMKE_00261	2.23e-117	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
COEAHMKE_00262	5.55e-30	-	-	-	K	-	-	-	Helix-turn-helix domain
COEAHMKE_00263	1.02e-72	-	-	-	K	-	-	-	Helix-turn-helix domain
COEAHMKE_00264	4.88e-124	-	-	-	S	-	-	-	Bacteriocin helveticin-J
COEAHMKE_00265	7.5e-99	-	-	-	S	-	-	-	SLAP domain
COEAHMKE_00266	2.19e-219	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
COEAHMKE_00267	8.61e-124	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
COEAHMKE_00268	1.85e-316	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
COEAHMKE_00269	1e-220	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
COEAHMKE_00270	1.81e-300	mod	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
COEAHMKE_00271	0.0	XK27_03440	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
COEAHMKE_00273	7.04e-47	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
COEAHMKE_00274	3.17e-43	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
COEAHMKE_00275	6.48e-76	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
COEAHMKE_00276	1.33e-38	-	-	-	L	-	-	-	Helix-turn-helix domain
COEAHMKE_00277	4.93e-94	-	-	-	L	-	-	-	Helix-turn-helix domain
COEAHMKE_00278	3.17e-205	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
COEAHMKE_00279	1.43e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
COEAHMKE_00280	1.07e-245	ysdE	-	-	P	-	-	-	Citrate transporter
COEAHMKE_00281	1.36e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
COEAHMKE_00282	1.49e-63	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
COEAHMKE_00283	8.95e-151	-	-	-	V	-	-	-	ABC transporter transmembrane region
COEAHMKE_00284	4.61e-96	-	-	-	V	-	-	-	ABC transporter transmembrane region
COEAHMKE_00285	2.7e-278	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
COEAHMKE_00286	1.3e-44	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
COEAHMKE_00287	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
COEAHMKE_00288	6.91e-84	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COEAHMKE_00289	2.08e-84	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COEAHMKE_00290	9.88e-39	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
COEAHMKE_00291	3.89e-305	-	-	-	L	-	-	-	Probable transposase
COEAHMKE_00297	1.1e-148	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
COEAHMKE_00298	6.31e-29	-	-	-	-	-	-	-	-
COEAHMKE_00300	3.73e-63	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
COEAHMKE_00301	8.06e-33	-	-	-	-	-	-	-	-
COEAHMKE_00302	4.15e-47	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
COEAHMKE_00303	1.97e-97	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
COEAHMKE_00305	2.61e-195	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
COEAHMKE_00307	1.05e-220	-	-	-	V	-	-	-	ABC transporter transmembrane region
COEAHMKE_00309	3.85e-61	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
COEAHMKE_00312	9.42e-145	-	-	-	S	-	-	-	SLAP domain
COEAHMKE_00313	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
COEAHMKE_00314	7.8e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
COEAHMKE_00315	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
COEAHMKE_00316	4.01e-209	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
COEAHMKE_00317	1.68e-226	degV1	-	-	S	-	-	-	DegV family
COEAHMKE_00318	2.99e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
COEAHMKE_00320	1.07e-34	-	-	-	S	-	-	-	Transglycosylase associated protein
COEAHMKE_00321	3.18e-302	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
COEAHMKE_00322	6.27e-155	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
COEAHMKE_00324	1.31e-196	-	-	-	S	-	-	-	Adenine-specific methyltransferase EcoRI
COEAHMKE_00325	4.22e-250	-	-	-	V	-	-	-	Protein of unknown function DUF262
COEAHMKE_00326	5.05e-51	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
COEAHMKE_00327	4.84e-34	-	-	-	K	-	-	-	Probable zinc-ribbon domain
COEAHMKE_00330	1.27e-21	-	-	-	-	-	-	-	-
COEAHMKE_00332	4.52e-63	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
COEAHMKE_00334	2.82e-210	-	-	-	EP	-	-	-	Plasmid replication protein
COEAHMKE_00335	3.88e-38	-	-	-	-	-	-	-	-
COEAHMKE_00336	1.2e-266	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
COEAHMKE_00337	4.16e-255	-	-	-	L	-	-	-	DNA methylAse
COEAHMKE_00338	0.0	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
COEAHMKE_00339	1.49e-312	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
COEAHMKE_00341	6.04e-203	-	-	-	V	-	-	-	ABC transporter transmembrane region
COEAHMKE_00343	1.21e-40	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
COEAHMKE_00344	6.64e-146	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COEAHMKE_00345	1.17e-168	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
COEAHMKE_00346	6.82e-185	-	-	-	L	-	-	-	Probable transposase
COEAHMKE_00347	4.88e-219	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
COEAHMKE_00348	2.15e-137	-	-	-	L	-	-	-	Resolvase, N terminal domain
COEAHMKE_00349	1.7e-179	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
COEAHMKE_00360	3.43e-164	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
COEAHMKE_00361	1.16e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
COEAHMKE_00362	2.84e-33	-	-	-	-	-	-	-	-
COEAHMKE_00363	2.04e-95	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
COEAHMKE_00369	1.34e-38	-	-	-	-	-	-	-	-
COEAHMKE_00370	1.06e-174	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
COEAHMKE_00371	2.35e-108	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
COEAHMKE_00372	4.02e-107	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
COEAHMKE_00373	6.43e-154	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COEAHMKE_00374	3.8e-292	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COEAHMKE_00375	7.98e-200	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
COEAHMKE_00376	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
COEAHMKE_00377	1.4e-152	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
COEAHMKE_00378	2.07e-163	-	-	-	-	-	-	-	-
COEAHMKE_00379	8.93e-300	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
COEAHMKE_00380	4.14e-311	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
COEAHMKE_00381	9.08e-20	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
COEAHMKE_00382	3.66e-133	-	-	-	E	-	-	-	amino acid
COEAHMKE_00383	2.64e-244	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
COEAHMKE_00384	1.5e-257	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
COEAHMKE_00387	2.73e-232	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COEAHMKE_00388	1.14e-312	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
COEAHMKE_00389	5.62e-310	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
COEAHMKE_00390	2.89e-75	-	-	-	-	-	-	-	-
COEAHMKE_00391	7.7e-110	-	-	-	-	-	-	-	-
COEAHMKE_00392	5.86e-39	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
COEAHMKE_00393	5.71e-171	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
COEAHMKE_00394	2.6e-47	-	-	-	S	-	-	-	DUF218 domain
COEAHMKE_00395	6.96e-170	-	-	-	S	-	-	-	DUF218 domain
COEAHMKE_00396	1.06e-100	-	-	-	-	-	-	-	-
COEAHMKE_00397	4.81e-140	-	-	-	-	-	-	-	-
COEAHMKE_00398	1.54e-85	-	-	-	EG	-	-	-	EamA-like transporter family
COEAHMKE_00399	5.96e-94	-	-	-	EG	-	-	-	EamA-like transporter family
COEAHMKE_00400	1.38e-108	-	-	-	M	-	-	-	NlpC/P60 family
COEAHMKE_00401	1.29e-169	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
COEAHMKE_00403	1.99e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
COEAHMKE_00404	3.49e-288	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
COEAHMKE_00405	1.91e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
COEAHMKE_00406	6.83e-225	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
COEAHMKE_00407	1.15e-142	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COEAHMKE_00408	7e-146	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
COEAHMKE_00409	1.13e-90	-	-	-	KLT	-	-	-	Protein kinase domain
COEAHMKE_00410	5.99e-26	-	-	-	-	-	-	-	-
COEAHMKE_00411	6.93e-85	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
COEAHMKE_00412	2.24e-106	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
COEAHMKE_00413	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
COEAHMKE_00414	5.86e-168	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
COEAHMKE_00415	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
COEAHMKE_00416	0.0	-	-	-	-	-	-	-	-
COEAHMKE_00417	1.67e-104	-	-	-	-	-	-	-	-
COEAHMKE_00418	1.05e-142	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
COEAHMKE_00419	1.12e-82	-	-	-	S	-	-	-	ASCH domain
COEAHMKE_00420	4.93e-70	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	lactoylglutathione lyase activity
COEAHMKE_00421	3.89e-71	-	-	-	-	-	-	-	-
COEAHMKE_00422	1.19e-43	-	-	-	-	-	-	-	-
COEAHMKE_00423	3.43e-64	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
COEAHMKE_00424	6.63e-113	yobV3	-	-	K	-	-	-	WYL domain
COEAHMKE_00425	3.47e-61	yobV3	-	-	K	-	-	-	WYL domain
COEAHMKE_00426	2.4e-89	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
COEAHMKE_00427	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
COEAHMKE_00428	6.85e-26	adh1	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
COEAHMKE_00429	8.38e-62	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
COEAHMKE_00430	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
COEAHMKE_00431	2.95e-43	-	-	-	C	-	-	-	Heavy-metal-associated domain
COEAHMKE_00432	3.92e-117	dpsB	-	-	P	-	-	-	Belongs to the Dps family
COEAHMKE_00433	1.39e-141	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
COEAHMKE_00434	2.41e-68	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
COEAHMKE_00435	4.41e-92	-	-	-	-	-	-	-	-
COEAHMKE_00436	1.69e-294	-	-	-	S	-	-	-	Protein of unknown function DUF262
COEAHMKE_00437	1.92e-135	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
COEAHMKE_00438	8.2e-145	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
COEAHMKE_00439	1.39e-248	-	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
COEAHMKE_00440	0.0	-	-	-	LV	-	-	-	Eco57I restriction-modification methylase
COEAHMKE_00441	6.36e-58	-	-	-	-	-	-	-	-
COEAHMKE_00442	7.7e-40	-	-	-	S	-	-	-	Abortive infection C-terminus
COEAHMKE_00443	0.0	-	-	-	S	-	-	-	PglZ domain
COEAHMKE_00444	0.0	-	-	-	-	-	-	-	-
COEAHMKE_00445	1.17e-29	repA	-	-	S	-	-	-	Replication initiator protein A
COEAHMKE_00446	0.0	-	-	-	E	-	-	-	Amino acid permease
COEAHMKE_00447	2.41e-235	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
COEAHMKE_00448	5.08e-304	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
COEAHMKE_00449	1.23e-27	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
COEAHMKE_00450	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
COEAHMKE_00451	1.16e-184	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
COEAHMKE_00452	2.29e-267	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
COEAHMKE_00453	2.06e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COEAHMKE_00454	3.08e-152	-	-	-	-	-	-	-	-
COEAHMKE_00455	6.89e-191	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
COEAHMKE_00456	1.69e-191	-	-	-	S	-	-	-	hydrolase
COEAHMKE_00457	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
COEAHMKE_00458	1.3e-218	ybbR	-	-	S	-	-	-	YbbR-like protein
COEAHMKE_00459	3.54e-193	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
COEAHMKE_00460	2.24e-262	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
COEAHMKE_00461	3.09e-178	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COEAHMKE_00462	6.45e-175	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COEAHMKE_00463	7.48e-261	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
COEAHMKE_00464	6.97e-209	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
COEAHMKE_00465	4.33e-127	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
COEAHMKE_00466	6.25e-117	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
COEAHMKE_00467	3.84e-233	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
COEAHMKE_00468	2.33e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
COEAHMKE_00469	4.17e-203	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
COEAHMKE_00470	3.58e-124	-	-	-	-	-	-	-	-
COEAHMKE_00471	3.84e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COEAHMKE_00472	6.01e-288	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
COEAHMKE_00473	1.65e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
COEAHMKE_00474	6.71e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
COEAHMKE_00476	6.94e-96	-	-	-	-	-	-	-	-
COEAHMKE_00477	1.42e-217	-	-	-	-	-	-	-	-
COEAHMKE_00478	0.0	ycaM	-	-	E	-	-	-	amino acid
COEAHMKE_00479	2.16e-171	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
COEAHMKE_00480	0.0	-	-	-	S	-	-	-	SH3-like domain
COEAHMKE_00481	4.05e-44	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
COEAHMKE_00482	1.19e-75	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
COEAHMKE_00483	5.56e-21	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
COEAHMKE_00484	9.69e-25	-	-	-	-	-	-	-	-
COEAHMKE_00485	4.9e-25	-	-	-	-	-	-	-	-
COEAHMKE_00486	2.81e-150	-	-	-	-	-	-	-	-
COEAHMKE_00487	1.34e-282	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
COEAHMKE_00488	6.58e-30	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
COEAHMKE_00489	4.7e-152	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
COEAHMKE_00491	4.88e-154	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
COEAHMKE_00492	3.18e-202	-	-	-	L	-	-	-	HNH nucleases
COEAHMKE_00493	1.38e-171	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
COEAHMKE_00494	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COEAHMKE_00495	8.48e-157	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
COEAHMKE_00496	2.78e-82	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
COEAHMKE_00497	4.26e-160	terC	-	-	P	-	-	-	Integral membrane protein TerC family
COEAHMKE_00498	6.98e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
COEAHMKE_00499	1.39e-167	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
COEAHMKE_00500	1.14e-111	-	-	-	-	-	-	-	-
COEAHMKE_00501	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COEAHMKE_00502	3.27e-228	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
COEAHMKE_00503	4.17e-187	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COEAHMKE_00504	2.84e-184	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
COEAHMKE_00505	3.74e-204	epsV	-	-	S	-	-	-	glycosyl transferase family 2
COEAHMKE_00506	1.77e-162	-	-	-	S	-	-	-	Alpha/beta hydrolase family
COEAHMKE_00507	5.93e-149	-	-	-	GM	-	-	-	NmrA-like family
COEAHMKE_00508	6.35e-73	-	-	-	-	-	-	-	-
COEAHMKE_00509	8.37e-232	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COEAHMKE_00510	1.89e-157	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
COEAHMKE_00511	4.16e-173	-	-	-	-	-	-	-	-
COEAHMKE_00512	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
COEAHMKE_00513	3.68e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
COEAHMKE_00514	2.69e-295	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
COEAHMKE_00515	7.25e-265	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
COEAHMKE_00516	6.11e-152	-	-	-	-	-	-	-	-
COEAHMKE_00517	3.81e-255	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
COEAHMKE_00518	1.35e-167	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
COEAHMKE_00519	4.03e-200	-	-	-	I	-	-	-	alpha/beta hydrolase fold
COEAHMKE_00520	3.6e-42	-	-	-	-	-	-	-	-
COEAHMKE_00522	1.75e-189	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
COEAHMKE_00523	6.43e-167	-	-	-	F	-	-	-	glutamine amidotransferase
COEAHMKE_00524	3.05e-190	-	-	-	-	-	-	-	-
COEAHMKE_00525	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
COEAHMKE_00526	2.17e-266	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
COEAHMKE_00527	2.61e-40	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
COEAHMKE_00528	8.93e-213	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
COEAHMKE_00529	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
COEAHMKE_00530	4.47e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
COEAHMKE_00531	1.47e-301	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
COEAHMKE_00532	1.19e-197	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
COEAHMKE_00533	5.59e-39	-	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
COEAHMKE_00534	1.34e-97	-	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
COEAHMKE_00535	1.1e-93	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
COEAHMKE_00536	3.8e-60	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
COEAHMKE_00537	5.37e-184	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
COEAHMKE_00538	1.76e-109	-	-	-	K	-	-	-	acetyltransferase
COEAHMKE_00539	2.7e-190	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
COEAHMKE_00540	3.37e-208	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
COEAHMKE_00541	1.85e-120	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
COEAHMKE_00542	1.44e-313	qacA	-	-	EGP	-	-	-	Major Facilitator
COEAHMKE_00547	1.04e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
COEAHMKE_00548	6.69e-81	-	-	-	-	-	-	-	-
COEAHMKE_00549	3.59e-119	-	-	-	L	-	-	-	helicase activity
COEAHMKE_00552	9.99e-40	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
COEAHMKE_00553	0.0	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
COEAHMKE_00554	2.56e-220	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
COEAHMKE_00555	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COEAHMKE_00556	6.64e-313	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
COEAHMKE_00557	1.98e-61	-	-	-	-	-	-	-	-
COEAHMKE_00558	2.1e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
COEAHMKE_00562	5.62e-28	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
COEAHMKE_00563	1.51e-121	-	-	-	E	-	-	-	Amino acid permease
COEAHMKE_00564	1.25e-201	-	-	-	E	-	-	-	Amino acid permease
COEAHMKE_00565	2.42e-123	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
COEAHMKE_00566	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
COEAHMKE_00567	3.65e-313	ynbB	-	-	P	-	-	-	aluminum resistance
COEAHMKE_00568	2.58e-101	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
COEAHMKE_00569	5.26e-224	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
COEAHMKE_00570	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
COEAHMKE_00571	1.53e-102	-	-	-	C	-	-	-	Flavodoxin
COEAHMKE_00572	2.32e-145	-	-	-	I	-	-	-	Acid phosphatase homologues
COEAHMKE_00573	1.46e-145	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
COEAHMKE_00574	5.31e-265	-	-	-	V	-	-	-	Beta-lactamase
COEAHMKE_00575	7.49e-196	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
COEAHMKE_00576	1.73e-121	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
COEAHMKE_00577	1.01e-294	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
COEAHMKE_00578	7.22e-282	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
COEAHMKE_00579	0.0	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
COEAHMKE_00580	9.66e-46	-	-	-	-	-	-	-	-
COEAHMKE_00581	4.31e-40	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
COEAHMKE_00582	1.45e-31	-	-	-	-	-	-	-	-
COEAHMKE_00583	0.0	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
COEAHMKE_00584	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
COEAHMKE_00585	1.76e-121	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
COEAHMKE_00586	3.06e-77	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
COEAHMKE_00587	2.89e-75	-	-	-	-	-	-	-	-
COEAHMKE_00588	3.29e-87	-	-	-	-	-	-	-	-
COEAHMKE_00589	3.53e-135	-	-	-	S	-	-	-	Fic/DOC family
COEAHMKE_00590	9.58e-132	-	-	-	-	-	-	-	-
COEAHMKE_00591	4.04e-265	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
COEAHMKE_00592	2.05e-116	-	-	-	-	-	-	-	-
COEAHMKE_00593	4.64e-256	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
COEAHMKE_00594	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
COEAHMKE_00595	6.82e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
COEAHMKE_00596	5.95e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
COEAHMKE_00597	1.64e-261	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
COEAHMKE_00598	1e-131	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COEAHMKE_00599	1.89e-90	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
COEAHMKE_00600	3.01e-84	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
COEAHMKE_00601	1.83e-196	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
COEAHMKE_00602	5.59e-251	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COEAHMKE_00603	4.4e-47	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COEAHMKE_00604	1.45e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
COEAHMKE_00605	8.09e-194	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
COEAHMKE_00606	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
COEAHMKE_00607	2.87e-101	-	-	-	S	-	-	-	ASCH
COEAHMKE_00608	6.69e-142	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
COEAHMKE_00609	5.6e-45	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
COEAHMKE_00610	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
COEAHMKE_00611	5.58e-221	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
COEAHMKE_00612	3.5e-312	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
COEAHMKE_00613	4.69e-189	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
COEAHMKE_00614	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
COEAHMKE_00615	2.64e-212	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
COEAHMKE_00616	4.86e-150	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
COEAHMKE_00617	6.36e-161	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
COEAHMKE_00618	8.06e-64	-	-	-	-	-	-	-	-
COEAHMKE_00619	3.82e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
COEAHMKE_00620	1.67e-74	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
COEAHMKE_00621	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
COEAHMKE_00622	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
COEAHMKE_00623	1.57e-234	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
COEAHMKE_00624	3.1e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
COEAHMKE_00625	1.17e-246	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
COEAHMKE_00626	1.39e-230	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
COEAHMKE_00627	6.07e-225	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COEAHMKE_00628	5.59e-200	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COEAHMKE_00629	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
COEAHMKE_00630	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
COEAHMKE_00631	1.56e-161	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
COEAHMKE_00632	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
COEAHMKE_00633	1.88e-217	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
COEAHMKE_00634	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
COEAHMKE_00635	3.87e-60	-	-	-	-	-	-	-	-
COEAHMKE_00636	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
COEAHMKE_00637	5.8e-247	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
COEAHMKE_00638	1.17e-73	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
COEAHMKE_00639	2.7e-289	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
COEAHMKE_00640	2.36e-60	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
COEAHMKE_00641	2.34e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
COEAHMKE_00642	2.41e-175	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
COEAHMKE_00643	2.28e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
COEAHMKE_00644	6.64e-154	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
COEAHMKE_00645	3.17e-191	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
COEAHMKE_00646	1.99e-145	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
COEAHMKE_00647	5.3e-49	ynzC	-	-	S	-	-	-	UPF0291 protein
COEAHMKE_00648	6.43e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
COEAHMKE_00649	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
COEAHMKE_00650	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
COEAHMKE_00651	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
COEAHMKE_00652	9.19e-287	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
COEAHMKE_00653	8.48e-145	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
COEAHMKE_00654	7.4e-254	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
COEAHMKE_00655	1.56e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
COEAHMKE_00656	4.33e-236	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
COEAHMKE_00657	2.38e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
COEAHMKE_00658	8.57e-122	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
COEAHMKE_00659	3.04e-176	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
COEAHMKE_00660	1.62e-189	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
COEAHMKE_00661	1.83e-253	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
COEAHMKE_00662	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
COEAHMKE_00663	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COEAHMKE_00664	4.83e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
COEAHMKE_00665	2.72e-263	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
COEAHMKE_00666	9.2e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
COEAHMKE_00667	2.2e-62	ylxQ	-	-	J	-	-	-	ribosomal protein
COEAHMKE_00668	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
COEAHMKE_00669	6.79e-79	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
COEAHMKE_00670	2.35e-211	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
COEAHMKE_00671	3.03e-230	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
COEAHMKE_00672	9.39e-85	-	-	-	-	-	-	-	-
COEAHMKE_00673	8.44e-21	-	-	-	K	-	-	-	Helix-turn-helix domain
COEAHMKE_00674	4.46e-165	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
COEAHMKE_00675	4.59e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
COEAHMKE_00676	1.13e-293	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
COEAHMKE_00677	2.6e-278	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
COEAHMKE_00678	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
COEAHMKE_00679	2.52e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
COEAHMKE_00680	3.04e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
COEAHMKE_00681	2.28e-307	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
COEAHMKE_00682	4.53e-55	-	-	-	-	-	-	-	-
COEAHMKE_00683	1.1e-102	uspA	-	-	T	-	-	-	universal stress protein
COEAHMKE_00684	5.62e-274	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
COEAHMKE_00685	3.61e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
COEAHMKE_00686	1.31e-67	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
COEAHMKE_00687	1.68e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
COEAHMKE_00688	1.21e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
COEAHMKE_00689	1.14e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
COEAHMKE_00690	3.04e-315	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
COEAHMKE_00691	2.25e-216	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
COEAHMKE_00692	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
COEAHMKE_00693	1.38e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COEAHMKE_00694	5.39e-83	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
COEAHMKE_00695	4.83e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COEAHMKE_00696	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
COEAHMKE_00697	2.15e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
COEAHMKE_00698	1.53e-241	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
COEAHMKE_00699	3.44e-200	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
COEAHMKE_00700	1.04e-233	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
COEAHMKE_00701	4.94e-146	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
COEAHMKE_00702	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
COEAHMKE_00705	6.05e-250	ampC	-	-	V	-	-	-	Beta-lactamase
COEAHMKE_00706	2.87e-52	-	-	-	EGP	-	-	-	Major Facilitator
COEAHMKE_00707	2.25e-194	-	-	-	EGP	-	-	-	Major Facilitator
COEAHMKE_00708	2.13e-186	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
COEAHMKE_00709	1.58e-301	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
COEAHMKE_00710	7.78e-300	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
COEAHMKE_00711	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
COEAHMKE_00712	8.76e-73	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
COEAHMKE_00713	4.25e-82	-	-	-	S	-	-	-	Enterocin A Immunity
COEAHMKE_00714	2.36e-169	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
COEAHMKE_00715	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
COEAHMKE_00716	1.52e-204	-	-	-	S	-	-	-	Phospholipase, patatin family
COEAHMKE_00717	2.65e-18	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
COEAHMKE_00718	1.57e-110	-	-	-	S	-	-	-	hydrolase
COEAHMKE_00719	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
COEAHMKE_00720	4.61e-133	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
COEAHMKE_00721	6.03e-35	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
COEAHMKE_00722	6.11e-94	-	-	-	-	-	-	-	-
COEAHMKE_00723	6.56e-112	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
COEAHMKE_00724	3.51e-53	-	-	-	-	-	-	-	-
COEAHMKE_00725	1.26e-11	-	-	-	C	-	-	-	nitroreductase
COEAHMKE_00726	1.31e-39	-	-	-	C	-	-	-	nitroreductase
COEAHMKE_00727	1.91e-314	yhdP	-	-	S	-	-	-	Transporter associated domain
COEAHMKE_00728	6.05e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
COEAHMKE_00729	1.18e-273	-	-	-	E	ko:K03294	-	ko00000	amino acid
COEAHMKE_00730	1.05e-162	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
COEAHMKE_00731	6.71e-268	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
COEAHMKE_00732	2.31e-314	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COEAHMKE_00734	5.82e-35	-	-	-	-	-	-	-	-
COEAHMKE_00735	3.82e-277	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
COEAHMKE_00736	5.57e-114	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
COEAHMKE_00737	3.48e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
COEAHMKE_00738	9.98e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
COEAHMKE_00739	7.94e-199	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
COEAHMKE_00740	3.48e-214	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
COEAHMKE_00741	1.03e-103	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
COEAHMKE_00742	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
COEAHMKE_00743	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
COEAHMKE_00744	1.47e-130	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
COEAHMKE_00745	1.5e-117	-	-	-	EGP	-	-	-	Major facilitator superfamily
COEAHMKE_00746	6.26e-79	-	-	-	EGP	-	-	-	Major facilitator superfamily
COEAHMKE_00747	1.17e-105	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
COEAHMKE_00748	3.1e-24	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
COEAHMKE_00749	7.79e-112	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
COEAHMKE_00750	1.23e-21	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
COEAHMKE_00751	2.71e-244	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
COEAHMKE_00752	1.27e-169	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
COEAHMKE_00753	9.06e-192	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
COEAHMKE_00754	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COEAHMKE_00755	4.08e-138	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COEAHMKE_00756	2.71e-192	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
COEAHMKE_00757	6.28e-157	-	-	-	K	-	-	-	sequence-specific DNA binding
COEAHMKE_00758	9.52e-211	-	-	-	S	-	-	-	SLAP domain
COEAHMKE_00759	1.77e-72	-	-	-	S	-	-	-	Bacteriocin helveticin-J
COEAHMKE_00760	2.37e-307	srrA1	-	-	G	ko:K02027,ko:K17244	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
COEAHMKE_00761	2.44e-207	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
COEAHMKE_00762	1.26e-212	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COEAHMKE_00763	3.83e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
COEAHMKE_00764	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
COEAHMKE_00765	3.01e-224	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
COEAHMKE_00766	1.06e-170	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
COEAHMKE_00768	1.7e-78	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
COEAHMKE_00769	1.47e-81	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
COEAHMKE_00770	4.18e-197	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
COEAHMKE_00771	3.29e-173	-	-	-	S	-	-	-	YSIRK type signal peptide
COEAHMKE_00772	3.86e-17	-	-	-	M	-	-	-	domain protein
COEAHMKE_00773	2.25e-133	-	-	-	M	-	-	-	domain protein
COEAHMKE_00774	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
COEAHMKE_00775	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
COEAHMKE_00776	4.08e-47	-	-	-	-	-	-	-	-
COEAHMKE_00777	3.27e-239	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
COEAHMKE_00778	2.82e-130	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COEAHMKE_00779	1.46e-240	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
COEAHMKE_00780	3.21e-208	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
COEAHMKE_00781	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
COEAHMKE_00782	7.3e-22	ps301	-	-	K	-	-	-	sequence-specific DNA binding
COEAHMKE_00783	1.35e-123	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
COEAHMKE_00784	5.52e-241	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
COEAHMKE_00785	1.8e-316	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
COEAHMKE_00786	2.36e-74	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0150
COEAHMKE_00788	6.38e-73	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
COEAHMKE_00789	1.64e-25	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
COEAHMKE_00790	2.68e-40	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
COEAHMKE_00791	1.08e-127	-	-	-	I	-	-	-	PAP2 superfamily
COEAHMKE_00792	6.8e-169	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
COEAHMKE_00793	2.03e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
COEAHMKE_00794	4.43e-98	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
COEAHMKE_00795	2.03e-111	yfhC	-	-	C	-	-	-	nitroreductase
COEAHMKE_00796	5.95e-14	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
COEAHMKE_00797	1.08e-102	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
COEAHMKE_00798	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
COEAHMKE_00799	9.74e-171	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COEAHMKE_00800	8.58e-290	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
COEAHMKE_00801	4.12e-47	-	-	-	-	-	-	-	-
COEAHMKE_00802	2.02e-101	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
COEAHMKE_00803	2.08e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
COEAHMKE_00804	1.81e-64	-	-	-	S	-	-	-	Cupredoxin-like domain
COEAHMKE_00805	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
COEAHMKE_00806	8.26e-22	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
COEAHMKE_00807	5.89e-48	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
COEAHMKE_00808	4.61e-99	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
COEAHMKE_00809	6.46e-27	-	-	-	-	-	-	-	-
COEAHMKE_00810	6.76e-269	-	-	-	-	-	-	-	-
COEAHMKE_00811	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
COEAHMKE_00812	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
COEAHMKE_00813	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
COEAHMKE_00814	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
COEAHMKE_00815	8.84e-188	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COEAHMKE_00816	1.31e-81	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
COEAHMKE_00817	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
COEAHMKE_00818	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
COEAHMKE_00819	4.3e-256	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
COEAHMKE_00820	4.08e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
COEAHMKE_00821	2.09e-267	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
COEAHMKE_00822	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COEAHMKE_00823	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COEAHMKE_00824	1.93e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
COEAHMKE_00825	7.17e-110	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
COEAHMKE_00826	1.89e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
COEAHMKE_00827	0.0	-	-	-	S	-	-	-	Fibronectin type III domain
COEAHMKE_00828	8.92e-310	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
COEAHMKE_00829	1.85e-28	-	-	-	-	-	-	-	-
COEAHMKE_00831	0.0	pepC1	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
COEAHMKE_00832	4e-152	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
COEAHMKE_00833	3.09e-267	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COEAHMKE_00834	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
COEAHMKE_00835	1.75e-95	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
COEAHMKE_00836	1.57e-97	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COEAHMKE_00837	6.33e-148	-	-	-	-	-	-	-	-
COEAHMKE_00839	2.55e-148	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
COEAHMKE_00840	2.35e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
COEAHMKE_00841	6.34e-118	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
COEAHMKE_00842	4.07e-141	-	-	-	S	ko:K06872	-	ko00000	TPM domain
COEAHMKE_00843	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
COEAHMKE_00844	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
COEAHMKE_00845	3.86e-189	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
COEAHMKE_00846	2.1e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
COEAHMKE_00847	6.96e-207	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
COEAHMKE_00848	3.35e-51	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
COEAHMKE_00849	3.54e-191	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
COEAHMKE_00850	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
COEAHMKE_00851	9.49e-136	-	-	-	S	-	-	-	SLAP domain
COEAHMKE_00853	9.66e-110	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
COEAHMKE_00854	7.05e-204	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COEAHMKE_00855	3.93e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
COEAHMKE_00856	2.04e-175	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COEAHMKE_00857	1.4e-80	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
COEAHMKE_00858	9.05e-258	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
COEAHMKE_00859	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COEAHMKE_00860	2.25e-88	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COEAHMKE_00861	1.79e-214	ldh3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
COEAHMKE_00862	5.22e-36	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
COEAHMKE_00863	1.67e-51	-	-	-	K	-	-	-	Helix-turn-helix domain
COEAHMKE_00864	5.79e-217	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
COEAHMKE_00865	0.0	-	-	-	S	-	-	-	membrane
COEAHMKE_00866	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
COEAHMKE_00867	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
COEAHMKE_00868	1.81e-128	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
COEAHMKE_00869	1.73e-148	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
COEAHMKE_00870	2.45e-44	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
COEAHMKE_00871	3.1e-92	yqhL	-	-	P	-	-	-	Rhodanese-like protein
COEAHMKE_00872	3.23e-218	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
COEAHMKE_00873	2.78e-37	ynbB	-	-	P	-	-	-	aluminum resistance
COEAHMKE_00874	5.31e-215	ynbB	-	-	P	-	-	-	aluminum resistance
COEAHMKE_00875	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
COEAHMKE_00876	8.93e-173	-	-	-	-	-	-	-	-
COEAHMKE_00877	9.18e-211	-	-	-	-	-	-	-	-
COEAHMKE_00878	6.91e-203	-	-	-	-	-	-	-	-
COEAHMKE_00879	2.56e-19	-	-	-	-	-	-	-	-
COEAHMKE_00880	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
COEAHMKE_00881	1.77e-200	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
COEAHMKE_00882	1.03e-134	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
COEAHMKE_00883	5.46e-108	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
COEAHMKE_00884	1.76e-314	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
COEAHMKE_00885	8.5e-212	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
COEAHMKE_00886	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
COEAHMKE_00887	4.51e-118	-	-	-	-	-	-	-	-
COEAHMKE_00888	1.51e-122	-	-	-	-	-	-	-	-
COEAHMKE_00889	3.9e-247	-	-	-	S	-	-	-	Domain of unknown function (DUF389)
COEAHMKE_00890	2.61e-36	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
COEAHMKE_00891	9.14e-174	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
COEAHMKE_00892	2.51e-43	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
COEAHMKE_00893	4.65e-71	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
COEAHMKE_00894	2.77e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
COEAHMKE_00895	1.23e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
COEAHMKE_00896	1.51e-121	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
COEAHMKE_00897	3.35e-270	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
COEAHMKE_00898	4.51e-156	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
COEAHMKE_00899	9.6e-143	yqeK	-	-	H	-	-	-	Hydrolase, HD family
COEAHMKE_00900	3.58e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
COEAHMKE_00901	1.09e-273	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
COEAHMKE_00902	2.47e-125	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
COEAHMKE_00903	2.12e-164	csrR	-	-	K	-	-	-	response regulator
COEAHMKE_00904	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
COEAHMKE_00905	7.64e-62	-	-	-	-	-	-	-	-
COEAHMKE_00906	7.72e-229	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
COEAHMKE_00907	1.34e-117	-	-	-	K	-	-	-	Protein of unknown function (DUF4065)
COEAHMKE_00908	1.5e-32	-	-	-	K	-	-	-	Protein of unknown function (DUF4065)
COEAHMKE_00909	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
COEAHMKE_00910	1.42e-268	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
COEAHMKE_00911	1.02e-279	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
COEAHMKE_00912	2.35e-79	-	-	-	-	-	-	-	-
COEAHMKE_00913	1.89e-34	-	-	-	K	-	-	-	DNA-templated transcription, initiation
COEAHMKE_00914	8.72e-12	-	-	-	K	-	-	-	DNA-templated transcription, initiation
COEAHMKE_00916	2.6e-242	-	-	-	S	-	-	-	SLAP domain
COEAHMKE_00917	2.13e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
COEAHMKE_00918	9.97e-40	-	-	-	-	-	-	-	-
COEAHMKE_00920	1.03e-113	-	-	-	-	-	-	-	-
COEAHMKE_00921	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
COEAHMKE_00922	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
COEAHMKE_00923	1.42e-287	yttB	-	-	EGP	-	-	-	Major Facilitator
COEAHMKE_00924	5.81e-292	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
COEAHMKE_00925	5.57e-129	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
COEAHMKE_00926	1.35e-180	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
COEAHMKE_00927	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
COEAHMKE_00928	1.54e-37	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
COEAHMKE_00929	1.94e-55	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
COEAHMKE_00930	2.26e-17	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
COEAHMKE_00931	4.81e-21	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
COEAHMKE_00932	4.43e-221	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
COEAHMKE_00933	1.69e-150	-	-	-	K	-	-	-	Rhodanese Homology Domain
COEAHMKE_00934	6.36e-71	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin
COEAHMKE_00935	6.68e-29	-	-	-	-	-	-	-	-
COEAHMKE_00936	2.74e-81	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
COEAHMKE_00937	2.49e-87	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
COEAHMKE_00938	3.81e-111	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
COEAHMKE_00939	3.28e-219	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
COEAHMKE_00940	3.47e-73	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
COEAHMKE_00941	1.89e-118	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
COEAHMKE_00942	4.49e-233	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
COEAHMKE_00943	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
COEAHMKE_00944	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
COEAHMKE_00945	1.8e-153	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
COEAHMKE_00946	3.79e-189	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
COEAHMKE_00947	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
COEAHMKE_00948	4.32e-279	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
COEAHMKE_00951	5.56e-214	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
COEAHMKE_00953	2.71e-128	-	-	-	-	-	-	-	-
COEAHMKE_00954	3.75e-98	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
COEAHMKE_00955	2.03e-13	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COEAHMKE_00956	5.04e-71	-	-	-	-	-	-	-	-
COEAHMKE_00957	1.82e-131	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
COEAHMKE_00958	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
COEAHMKE_00959	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
COEAHMKE_00960	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
COEAHMKE_00961	2.1e-99	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
COEAHMKE_00962	1.76e-178	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COEAHMKE_00963	2.12e-120	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
COEAHMKE_00964	1.4e-44	-	-	-	-	-	-	-	-
COEAHMKE_00965	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
COEAHMKE_00966	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
COEAHMKE_00967	1.21e-33	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
COEAHMKE_00968	8.63e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
COEAHMKE_00969	3.82e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
COEAHMKE_00970	3.02e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
COEAHMKE_00971	7.46e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
COEAHMKE_00972	4.05e-220	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
COEAHMKE_00973	9.02e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
COEAHMKE_00974	2.49e-185	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COEAHMKE_00975	2.31e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COEAHMKE_00976	1.43e-151	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
COEAHMKE_00977	3.34e-13	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
COEAHMKE_00978	3.89e-197	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
COEAHMKE_00979	1.77e-109	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
COEAHMKE_00980	2.67e-71	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
COEAHMKE_00981	2.28e-116	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
COEAHMKE_00982	4.71e-149	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
COEAHMKE_00983	9.21e-120	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
COEAHMKE_00984	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COEAHMKE_00985	6.03e-57	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
COEAHMKE_00986	5.33e-141	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
COEAHMKE_00987	5.61e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
COEAHMKE_00988	8.42e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
COEAHMKE_00989	6.21e-68	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
COEAHMKE_00990	3.42e-198	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
COEAHMKE_00991	1.35e-78	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
COEAHMKE_00992	2.6e-197	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
COEAHMKE_00993	4.01e-181	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
COEAHMKE_00994	1.11e-113	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
COEAHMKE_00995	2.22e-168	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
COEAHMKE_00996	1.6e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
COEAHMKE_00997	2.16e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
COEAHMKE_00998	1.66e-158	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
COEAHMKE_00999	1.39e-232	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
COEAHMKE_01000	9.39e-167	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
COEAHMKE_01001	3.87e-12	-	-	-	S	-	-	-	Toxin ToxN, type III toxin-antitoxin system
COEAHMKE_01002	1.35e-140	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
COEAHMKE_01003	1.97e-136	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
COEAHMKE_01004	1.52e-140	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
COEAHMKE_01005	3.89e-46	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
COEAHMKE_01006	5.37e-274	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
COEAHMKE_01007	2.43e-17	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
COEAHMKE_01008	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
COEAHMKE_01009	3.4e-150	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
COEAHMKE_01010	4.34e-101	-	-	-	K	-	-	-	LytTr DNA-binding domain
COEAHMKE_01011	1.26e-161	-	-	-	S	-	-	-	membrane
COEAHMKE_01012	1.39e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
COEAHMKE_01013	3.26e-290	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
COEAHMKE_01014	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
COEAHMKE_01015	7.04e-63	-	-	-	-	-	-	-	-
COEAHMKE_01016	9.71e-116	-	-	-	-	-	-	-	-
COEAHMKE_01017	9.06e-60	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
COEAHMKE_01018	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
COEAHMKE_01019	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
COEAHMKE_01020	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
COEAHMKE_01021	1.47e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
COEAHMKE_01022	4.17e-237	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
COEAHMKE_01023	1.42e-76	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
COEAHMKE_01024	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
COEAHMKE_01025	9.26e-270	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
COEAHMKE_01026	1.56e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
COEAHMKE_01027	5.24e-312	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
COEAHMKE_01028	4.66e-83	-	-	-	-	-	-	-	-
COEAHMKE_01029	1.1e-107	-	-	-	-	-	-	-	-
COEAHMKE_01030	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
COEAHMKE_01031	5.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
COEAHMKE_01032	2.69e-95	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
COEAHMKE_01033	1.18e-66	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
COEAHMKE_01034	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
COEAHMKE_01035	2.19e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
COEAHMKE_01036	5.38e-63	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
COEAHMKE_01037	3.63e-91	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
COEAHMKE_01038	3.98e-188	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
COEAHMKE_01039	2.16e-148	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
COEAHMKE_01040	1.05e-191	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
COEAHMKE_01041	3.11e-28	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
COEAHMKE_01042	5.94e-65	-	-	-	-	-	-	-	-
COEAHMKE_01045	2.71e-200	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
COEAHMKE_01046	5.75e-261	XK27_02480	-	-	EGP	-	-	-	Major facilitator Superfamily
COEAHMKE_01048	1.85e-22	-	-	-	-	-	-	-	-
COEAHMKE_01049	8.1e-104	-	-	-	GM	-	-	-	NAD(P)H-binding
COEAHMKE_01050	1.34e-153	-	-	-	C	-	-	-	Aldo keto reductase
COEAHMKE_01051	3.92e-172	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
COEAHMKE_01052	2.6e-44	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
COEAHMKE_01054	8.11e-56	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
COEAHMKE_01055	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
COEAHMKE_01056	2.72e-199	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
COEAHMKE_01057	3.54e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
COEAHMKE_01058	2.81e-22	-	-	-	-	-	-	-	-
COEAHMKE_01059	5.79e-65	-	-	-	-	-	-	-	-
COEAHMKE_01060	6.93e-39	-	-	-	-	-	-	-	-
COEAHMKE_01061	2.57e-159	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
COEAHMKE_01062	5.83e-12	-	-	-	-	-	-	-	-
COEAHMKE_01064	9.29e-222	pbpX2	-	-	V	-	-	-	Beta-lactamase
COEAHMKE_01065	2.09e-303	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
COEAHMKE_01066	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COEAHMKE_01067	9.88e-303	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
COEAHMKE_01068	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COEAHMKE_01069	2.63e-26	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
COEAHMKE_01070	2.34e-66	-	-	-	-	-	-	-	-
COEAHMKE_01071	8.61e-273	-	-	-	S	-	-	-	Membrane
COEAHMKE_01072	6.18e-33	ykuL	-	-	S	-	-	-	IMP dehydrogenase activity
COEAHMKE_01073	5.53e-147	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
COEAHMKE_01074	2.65e-217	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
COEAHMKE_01075	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COEAHMKE_01076	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
COEAHMKE_01077	2.94e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COEAHMKE_01078	5.99e-266	camS	-	-	S	-	-	-	sex pheromone
COEAHMKE_01079	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
COEAHMKE_01080	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
COEAHMKE_01081	3.4e-145	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
COEAHMKE_01083	1.34e-113	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
COEAHMKE_01084	4.89e-176	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
COEAHMKE_01085	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
COEAHMKE_01086	2.11e-286	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
COEAHMKE_01087	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
COEAHMKE_01088	6.77e-73	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
COEAHMKE_01089	1.34e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
COEAHMKE_01090	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COEAHMKE_01091	1.64e-262	-	-	-	M	-	-	-	Glycosyl transferases group 1
COEAHMKE_01092	1.69e-172	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
COEAHMKE_01093	2.16e-18	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
COEAHMKE_01094	7.99e-97	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
COEAHMKE_01095	5.43e-167	-	-	-	S	-	-	-	Phage Mu protein F like protein
COEAHMKE_01096	3.62e-22	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
COEAHMKE_01097	2.34e-158	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
COEAHMKE_01098	2.25e-72	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
COEAHMKE_01099	9.39e-157	-	-	-	L	-	-	-	Transposase DDE domain
COEAHMKE_01102	2.08e-202	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
COEAHMKE_01103	3.6e-216	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
COEAHMKE_01104	2.53e-204	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
COEAHMKE_01105	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
COEAHMKE_01106	7.73e-256	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
COEAHMKE_01107	9.47e-202	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
COEAHMKE_01108	5.62e-187	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COEAHMKE_01109	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
COEAHMKE_01110	1.17e-307	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
COEAHMKE_01111	1.36e-214	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
COEAHMKE_01112	1.97e-208	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
COEAHMKE_01113	5.77e-127	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
COEAHMKE_01114	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
COEAHMKE_01115	2.82e-12	-	-	-	-	-	-	-	-
COEAHMKE_01116	9.49e-302	-	-	-	S	-	-	-	Domain of unknown function (DUF3883)
COEAHMKE_01117	1.34e-277	-	-	-	S	-	-	-	SLAP domain
COEAHMKE_01119	2.86e-40	-	-	-	-	-	-	-	-
COEAHMKE_01121	4.61e-36	-	-	-	-	-	-	-	-
COEAHMKE_01122	4.03e-146	-	-	-	G	-	-	-	Peptidase_C39 like family
COEAHMKE_01123	1.04e-119	-	-	-	M	-	-	-	NlpC/P60 family
COEAHMKE_01124	3.07e-28	-	-	-	M	-	-	-	NlpC/P60 family
COEAHMKE_01125	1.66e-15	-	-	-	M	-	-	-	NlpC/P60 family
COEAHMKE_01127	5.12e-71	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
COEAHMKE_01128	2.29e-196	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
COEAHMKE_01129	1.63e-159	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
COEAHMKE_01130	6.37e-62	-	-	-	-	-	-	-	-
COEAHMKE_01131	1.76e-53	-	-	-	-	-	-	-	-
COEAHMKE_01132	2.2e-264	-	-	-	G	-	-	-	Major Facilitator Superfamily
COEAHMKE_01133	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
COEAHMKE_01134	2.16e-213	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
COEAHMKE_01135	2.99e-242	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
COEAHMKE_01136	6.47e-312	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
COEAHMKE_01137	1.23e-236	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
COEAHMKE_01138	3.07e-30	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
COEAHMKE_01139	8.07e-49	-	-	-	F	-	-	-	nucleoside 2-deoxyribosyltransferase
COEAHMKE_01140	3.28e-05	fabZ	3.5.1.108, 4.2.1.59	-	IM	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	FabA-like domain
COEAHMKE_01142	5.4e-188	ydiM	-	-	G	-	-	-	Major facilitator superfamily
COEAHMKE_01143	3.62e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
COEAHMKE_01144	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
COEAHMKE_01145	9.47e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
COEAHMKE_01146	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
COEAHMKE_01147	6.65e-234	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
COEAHMKE_01148	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
COEAHMKE_01149	1.26e-215	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
COEAHMKE_01150	1.48e-216	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
COEAHMKE_01151	1.62e-80	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COEAHMKE_01152	1.22e-167	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
COEAHMKE_01153	1.16e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
COEAHMKE_01154	3.66e-165	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
COEAHMKE_01155	1.31e-149	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
COEAHMKE_01156	5.93e-57	-	-	-	M	-	-	-	Lysin motif
COEAHMKE_01157	2.57e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
COEAHMKE_01158	6.32e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
COEAHMKE_01159	1.05e-311	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
COEAHMKE_01160	1.17e-56	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
COEAHMKE_01161	3.68e-295	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
COEAHMKE_01162	8.42e-204	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
COEAHMKE_01163	4.4e-288	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
COEAHMKE_01164	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
COEAHMKE_01165	3.84e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
COEAHMKE_01166	5.47e-137	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
COEAHMKE_01167	4.67e-63	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
COEAHMKE_01168	1.63e-197	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
COEAHMKE_01169	1.24e-61	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
COEAHMKE_01170	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
COEAHMKE_01171	1.75e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
COEAHMKE_01172	1.66e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
COEAHMKE_01173	1.45e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
COEAHMKE_01174	6.37e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
COEAHMKE_01175	2.1e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
COEAHMKE_01176	1.64e-43	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
COEAHMKE_01177	7.13e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
COEAHMKE_01178	1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COEAHMKE_01179	2.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
COEAHMKE_01180	5.05e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
COEAHMKE_01181	3.67e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
COEAHMKE_01182	2.63e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
COEAHMKE_01183	2.22e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
COEAHMKE_01184	1.73e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
COEAHMKE_01185	5.1e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
COEAHMKE_01186	2.61e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
COEAHMKE_01187	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
COEAHMKE_01188	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
COEAHMKE_01189	1.46e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
COEAHMKE_01190	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
COEAHMKE_01191	3.62e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COEAHMKE_01192	4.49e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
COEAHMKE_01193	2.69e-195	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COEAHMKE_01194	3.56e-191	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COEAHMKE_01195	5.22e-179	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COEAHMKE_01196	6.08e-183	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
COEAHMKE_01197	6.51e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
COEAHMKE_01198	1.18e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
COEAHMKE_01199	2.17e-61	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
COEAHMKE_01200	1.17e-137	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
COEAHMKE_01201	1.97e-85	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
COEAHMKE_01202	2.01e-18	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
COEAHMKE_01203	1.67e-113	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
COEAHMKE_01204	1.36e-173	-	-	-	M	-	-	-	Phosphotransferase enzyme family
COEAHMKE_01205	1.03e-116	-	-	-	S	-	-	-	AAA domain
COEAHMKE_01207	2.05e-121	-	-	-	S	-	-	-	F420-0:Gamma-glutamyl ligase
COEAHMKE_01208	2.08e-75	codA	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
COEAHMKE_01209	4.46e-127	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
COEAHMKE_01210	4.44e-104	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
COEAHMKE_01211	1.29e-63	-	-	-	-	-	-	-	-
COEAHMKE_01212	4.89e-54	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
COEAHMKE_01213	3.1e-106	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
COEAHMKE_01214	2.13e-139	-	-	-	S	-	-	-	Domain of unknown function (DUF4411)
COEAHMKE_01215	7.21e-282	-	-	-	E	-	-	-	IrrE N-terminal-like domain
COEAHMKE_01217	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
COEAHMKE_01218	7e-268	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
COEAHMKE_01219	2.66e-309	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
COEAHMKE_01220	2.22e-231	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
COEAHMKE_01221	5.63e-120	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
COEAHMKE_01222	3.59e-211	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
COEAHMKE_01223	1.08e-155	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
COEAHMKE_01224	5.51e-147	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
COEAHMKE_01225	1.45e-152	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
COEAHMKE_01226	1.79e-248	-	-	-	S	-	-	-	DUF218 domain
COEAHMKE_01227	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COEAHMKE_01228	1.55e-125	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
COEAHMKE_01229	2.08e-204	-	-	-	S	-	-	-	Aldo/keto reductase family
COEAHMKE_01230	3.84e-172	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
COEAHMKE_01231	2.18e-128	-	-	-	K	-	-	-	rpiR family
COEAHMKE_01232	8.5e-183	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
COEAHMKE_01233	1.76e-195	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Beta-lactamase
COEAHMKE_01235	4.39e-159	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
COEAHMKE_01236	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
COEAHMKE_01238	1.57e-150	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
COEAHMKE_01239	6.91e-165	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
COEAHMKE_01240	3.03e-187	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
COEAHMKE_01241	5.85e-293	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
COEAHMKE_01242	2.14e-220	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
COEAHMKE_01243	2.89e-22	-	-	-	-	-	-	-	-
COEAHMKE_01244	3.56e-93	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
COEAHMKE_01245	5.87e-99	M1-431	-	-	S	-	-	-	Protein of unknown function (DUF1706)
COEAHMKE_01246	2.39e-115	-	-	-	-	-	-	-	-
COEAHMKE_01247	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
COEAHMKE_01248	2.18e-215	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
COEAHMKE_01249	2.27e-59	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
COEAHMKE_01250	5.82e-250	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
COEAHMKE_01251	1.32e-113	-	-	-	I	-	-	-	Alpha/beta hydrolase family
COEAHMKE_01252	2.71e-66	-	-	-	I	-	-	-	Alpha/beta hydrolase family
COEAHMKE_01253	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
COEAHMKE_01254	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
COEAHMKE_01255	8.04e-64	-	-	-	-	-	-	-	-
COEAHMKE_01256	5.49e-53	-	-	-	-	-	-	-	-
COEAHMKE_01257	1.01e-83	-	-	-	M	-	-	-	Rib/alpha-like repeat
COEAHMKE_01258	1.21e-214	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
COEAHMKE_01262	3.69e-13	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
COEAHMKE_01263	5.34e-31	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
COEAHMKE_01265	4.95e-203	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
COEAHMKE_01266	1.07e-195	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
COEAHMKE_01267	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COEAHMKE_01268	3.75e-109	-	3.4.21.96	-	S	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	SLAP domain
COEAHMKE_01269	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
COEAHMKE_01270	1.71e-202	lysR5	-	-	K	-	-	-	LysR substrate binding domain
COEAHMKE_01271	1.32e-33	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
COEAHMKE_01272	3.75e-71	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
COEAHMKE_01273	6.12e-114	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
COEAHMKE_01274	7.7e-17	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
COEAHMKE_01275	5.91e-184	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
COEAHMKE_01276	3.04e-88	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
COEAHMKE_01277	1.33e-66	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
COEAHMKE_01278	7.45e-124	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
COEAHMKE_01279	1.29e-279	-	-	-	S	-	-	-	Sterol carrier protein domain
COEAHMKE_01280	5.55e-27	-	-	-	-	-	-	-	-
COEAHMKE_01281	5.72e-137	-	-	-	K	-	-	-	LysR substrate binding domain
COEAHMKE_01282	2.71e-98	-	-	-	-	-	-	-	-
COEAHMKE_01284	4.4e-150	-	3.6.3.44	-	V	ko:K02021,ko:K06147,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
COEAHMKE_01286	4.04e-170	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
COEAHMKE_01287	8.23e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
COEAHMKE_01288	1.54e-248	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
COEAHMKE_01289	2.97e-211	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
COEAHMKE_01290	1.26e-107	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
COEAHMKE_01291	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
COEAHMKE_01292	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
COEAHMKE_01293	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
COEAHMKE_01294	7.7e-80	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
COEAHMKE_01295	3.46e-241	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
COEAHMKE_01296	1.64e-202	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
COEAHMKE_01297	5.87e-229	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
COEAHMKE_01298	9.21e-50	-	-	-	-	-	-	-	-
COEAHMKE_01299	1.19e-235	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
COEAHMKE_01300	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COEAHMKE_01301	3.81e-123	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
COEAHMKE_01302	4.17e-172	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
COEAHMKE_01303	8.28e-310	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
COEAHMKE_01304	2.4e-152	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
COEAHMKE_01305	3.21e-267	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
COEAHMKE_01306	2.03e-284	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
COEAHMKE_01307	8.88e-248	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
COEAHMKE_01308	3e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COEAHMKE_01309	1.26e-184	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
COEAHMKE_01310	1.14e-170	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
COEAHMKE_01311	6.17e-300	ymfH	-	-	S	-	-	-	Peptidase M16
COEAHMKE_01312	1.93e-287	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
COEAHMKE_01313	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
COEAHMKE_01314	4.46e-90	WQ51_03320	-	-	S	-	-	-	Protein of unknown function (DUF1149)
COEAHMKE_01315	1.23e-135	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
COEAHMKE_01316	8.55e-270	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
COEAHMKE_01317	1.35e-85	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
COEAHMKE_01318	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
COEAHMKE_01319	1.75e-256	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
COEAHMKE_01320	6.52e-59	-	-	-	S	-	-	-	SNARE associated Golgi protein
COEAHMKE_01321	5.71e-38	-	-	-	S	-	-	-	SNARE associated Golgi protein
COEAHMKE_01322	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
COEAHMKE_01323	6.11e-38	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
COEAHMKE_01324	8.17e-158	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
COEAHMKE_01325	4.35e-198	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
COEAHMKE_01326	1.15e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
COEAHMKE_01327	8.48e-145	-	-	-	S	-	-	-	CYTH
COEAHMKE_01328	5.3e-144	yjbH	-	-	Q	-	-	-	Thioredoxin
COEAHMKE_01329	1.53e-203	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
COEAHMKE_01330	3.26e-172	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
COEAHMKE_01331	1.08e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
COEAHMKE_01332	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COEAHMKE_01333	1.29e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
COEAHMKE_01334	5.25e-37	-	-	-	-	-	-	-	-
COEAHMKE_01335	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
COEAHMKE_01336	4.17e-60	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
COEAHMKE_01337	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
COEAHMKE_01338	1.2e-205	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
COEAHMKE_01339	2.6e-96	-	-	-	-	-	-	-	-
COEAHMKE_01340	1.05e-112	-	-	-	-	-	-	-	-
COEAHMKE_01341	2.89e-185	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
COEAHMKE_01342	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COEAHMKE_01343	2.93e-127	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
COEAHMKE_01347	1.64e-108	-	-	-	L	-	-	-	Integrase
COEAHMKE_01348	7.18e-124	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
COEAHMKE_01349	1.12e-90	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
COEAHMKE_01350	2.73e-60	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
COEAHMKE_01351	5.31e-78	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
COEAHMKE_01353	1.11e-37	-	-	-	S	-	-	-	HicB family
COEAHMKE_01354	2.3e-42	bioY2	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin synthase
COEAHMKE_01355	4.04e-81	-	-	-	S	-	-	-	Alpha/beta hydrolase family
COEAHMKE_01356	5.82e-34	-	-	-	I	-	-	-	carboxylic ester hydrolase activity
COEAHMKE_01357	3.9e-114	-	-	-	S	-	-	-	Membrane
COEAHMKE_01358	4.21e-63	-	-	-	S	-	-	-	Membrane
COEAHMKE_01359	7.05e-157	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
COEAHMKE_01360	5e-185	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
COEAHMKE_01361	1.17e-114	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COEAHMKE_01362	2.26e-140	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
COEAHMKE_01363	2.15e-113	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
COEAHMKE_01364	7.56e-77	-	-	-	S	-	-	-	YjbR
COEAHMKE_01366	7.31e-81	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
COEAHMKE_01367	1.06e-48	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
COEAHMKE_01368	2.34e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
COEAHMKE_01369	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
COEAHMKE_01370	5.17e-08	-	-	-	S	-	-	-	Protein of unknown function (DUF3923)
COEAHMKE_01372	6.34e-136	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
COEAHMKE_01373	1.96e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
COEAHMKE_01374	9.74e-98	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
COEAHMKE_01375	5.66e-124	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
COEAHMKE_01376	1.82e-126	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
COEAHMKE_01377	1.06e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
COEAHMKE_01378	7.44e-230	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
COEAHMKE_01379	2.12e-114	cvpA	-	-	S	-	-	-	Colicin V production protein
COEAHMKE_01380	9.37e-169	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
COEAHMKE_01381	3.14e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
COEAHMKE_01382	2.77e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
COEAHMKE_01383	3.96e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
COEAHMKE_01384	1.83e-58	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
COEAHMKE_01385	2.8e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
COEAHMKE_01386	1.88e-178	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
COEAHMKE_01387	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
COEAHMKE_01388	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
COEAHMKE_01389	2.9e-157	vanR	-	-	K	-	-	-	response regulator
COEAHMKE_01390	2.54e-267	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
COEAHMKE_01391	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
COEAHMKE_01392	3.86e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
COEAHMKE_01393	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
COEAHMKE_01394	7.07e-38	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
COEAHMKE_01395	8.7e-44	ymdB	-	-	S	-	-	-	Macro domain protein
COEAHMKE_01396	1.52e-09	ymdB	-	-	S	-	-	-	Macro domain protein
COEAHMKE_01397	1.14e-196	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
COEAHMKE_01398	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COEAHMKE_01399	1.29e-280	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
COEAHMKE_01400	3.19e-263	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
COEAHMKE_01401	1.68e-149	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
COEAHMKE_01402	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
COEAHMKE_01403	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
COEAHMKE_01404	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
COEAHMKE_01405	4.29e-55	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COEAHMKE_01406	5.31e-115	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
COEAHMKE_01407	1.43e-221	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
COEAHMKE_01408	1.55e-79	-	-	-	-	-	-	-	-
COEAHMKE_01409	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
COEAHMKE_01410	4.97e-97	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
COEAHMKE_01411	1.74e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
COEAHMKE_01412	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
COEAHMKE_01413	3.72e-282	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
COEAHMKE_01414	4.5e-280	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
COEAHMKE_01415	3.02e-46	-	-	-	S	-	-	-	reductase
COEAHMKE_01416	1.77e-95	-	-	-	S	-	-	-	reductase
COEAHMKE_01417	1.58e-110	yxeH	-	-	S	-	-	-	hydrolase
COEAHMKE_01418	2.29e-34	yxeH	-	-	S	-	-	-	hydrolase
COEAHMKE_01419	6.37e-14	yxeH	-	-	S	-	-	-	hydrolase
COEAHMKE_01420	3.34e-16	gyaR	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COEAHMKE_01421	4.04e-101	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COEAHMKE_01422	4.95e-57	gyaR	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COEAHMKE_01423	3.25e-270	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
COEAHMKE_01424	2.07e-26	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
COEAHMKE_01425	6.16e-98	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
COEAHMKE_01426	3.32e-14	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
COEAHMKE_01427	2.65e-165	-	-	-	-	-	-	-	-
COEAHMKE_01428	3.43e-11	ohr	-	-	O	-	-	-	redox protein regulator of disulfide bond formation
COEAHMKE_01429	1.63e-216	-	1.1.1.29	-	CH	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COEAHMKE_01430	4.7e-62	-	-	-	-	-	-	-	-
COEAHMKE_01431	4.72e-72	-	-	-	-	-	-	-	-
COEAHMKE_01432	3.41e-78	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
COEAHMKE_01433	1.1e-277	-	-	-	EGP	ko:K08196,ko:K08369	-	ko00000,ko02000	Major Facilitator
COEAHMKE_01434	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
COEAHMKE_01435	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
COEAHMKE_01436	2.11e-271	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
COEAHMKE_01437	1.64e-79	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
COEAHMKE_01439	4.69e-282	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
COEAHMKE_01440	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
COEAHMKE_01441	4.6e-251	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
COEAHMKE_01444	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
COEAHMKE_01445	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
COEAHMKE_01446	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
COEAHMKE_01447	8.26e-106	-	-	-	-	-	-	-	-
COEAHMKE_01448	3.79e-141	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
COEAHMKE_01449	4.13e-187	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COEAHMKE_01450	3.54e-165	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COEAHMKE_01451	2.12e-178	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
COEAHMKE_01452	5.12e-197	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
COEAHMKE_01454	1.6e-113	usp5	-	-	T	-	-	-	universal stress protein
COEAHMKE_01455	8.38e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
COEAHMKE_01456	2.55e-111	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
COEAHMKE_01457	8.67e-111	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
COEAHMKE_01458	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
COEAHMKE_01459	1.39e-60	aspD	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	Aminotransferase class I and II
COEAHMKE_01460	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
COEAHMKE_01461	6.82e-171	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COEAHMKE_01462	7e-304	-	-	-	S	-	-	-	response to antibiotic
COEAHMKE_01463	2.84e-130	-	-	-	-	-	-	-	-
COEAHMKE_01464	2.4e-146	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
COEAHMKE_01465	2.95e-52	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
COEAHMKE_01466	7.16e-31	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
COEAHMKE_01467	1.86e-26	-	-	-	-	-	-	-	-
COEAHMKE_01468	7.24e-22	-	-	-	-	-	-	-	-
COEAHMKE_01469	3.19e-239	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
COEAHMKE_01470	1.04e-169	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
COEAHMKE_01471	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
COEAHMKE_01472	3.29e-52	-	-	-	-	-	-	-	-
COEAHMKE_01473	8.26e-60	-	-	-	-	-	-	-	-
COEAHMKE_01474	1.68e-121	-	-	-	-	-	-	-	-
COEAHMKE_01475	8.65e-52	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
COEAHMKE_01476	2.09e-188	-	-	-	V	-	-	-	Beta-lactamase
COEAHMKE_01477	1.66e-198	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
COEAHMKE_01479	1.66e-42	-	-	-	-	-	-	-	-
COEAHMKE_01480	3.27e-53	-	-	-	-	-	-	-	-
COEAHMKE_01481	5.94e-118	-	-	-	L	-	-	-	NUDIX domain
COEAHMKE_01482	5.16e-218	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
COEAHMKE_01483	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
COEAHMKE_01484	5.02e-20	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
COEAHMKE_01485	2.74e-145	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
COEAHMKE_01486	1.03e-133	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
COEAHMKE_01487	2.93e-119	-	-	-	K	-	-	-	Virulence activator alpha C-term
COEAHMKE_01488	9.06e-159	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
COEAHMKE_01489	4.31e-195	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
COEAHMKE_01490	7.38e-310	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
COEAHMKE_01492	7.41e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
COEAHMKE_01493	1.55e-282	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
COEAHMKE_01494	2.66e-48	-	-	-	S	-	-	-	Enterocin A Immunity
COEAHMKE_01495	4.39e-177	yxeH	-	-	S	-	-	-	hydrolase
COEAHMKE_01496	1.86e-117	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
COEAHMKE_01497	2.88e-113	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
COEAHMKE_01498	1.3e-240	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
COEAHMKE_01499	8.96e-173	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
COEAHMKE_01500	2.6e-183	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
COEAHMKE_01501	5.09e-202	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
COEAHMKE_01502	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
COEAHMKE_01503	1.64e-94	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
COEAHMKE_01504	5.23e-102	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
COEAHMKE_01505	8.97e-293	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
COEAHMKE_01506	1.8e-163	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
COEAHMKE_01507	1.66e-215	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
COEAHMKE_01508	1.53e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
COEAHMKE_01509	3.68e-230	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
COEAHMKE_01510	2.06e-103	-	-	-	K	-	-	-	Transcriptional regulator
COEAHMKE_01511	5.77e-102	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
COEAHMKE_01512	2.53e-31	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
COEAHMKE_01513	2.42e-168	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
COEAHMKE_01514	1.27e-22	-	-	-	S	-	-	-	Transglycosylase associated protein
COEAHMKE_01515	2.66e-57	-	-	-	S	-	-	-	Enterocin A Immunity
COEAHMKE_01516	2.38e-60	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
COEAHMKE_01517	8.58e-112	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
COEAHMKE_01518	1.88e-43	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
COEAHMKE_01519	5.08e-129	-	-	-	E	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COEAHMKE_01520	1.29e-141	potC3	-	-	E	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
COEAHMKE_01521	5.74e-170	potA11	3.6.3.30	-	P	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
COEAHMKE_01522	4.27e-189	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
COEAHMKE_01523	7.1e-312	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
COEAHMKE_01524	2e-90	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
COEAHMKE_01525	7.72e-297	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
COEAHMKE_01526	9.17e-172	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
COEAHMKE_01527	1.91e-151	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
COEAHMKE_01528	2.56e-202	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
COEAHMKE_01529	2.66e-57	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
COEAHMKE_01530	2.15e-48	-	-	-	S	-	-	-	Transglycosylase associated protein
COEAHMKE_01531	3.26e-29	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
COEAHMKE_01532	1.95e-115	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
COEAHMKE_01533	5.82e-35	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
COEAHMKE_01534	1.1e-69	-	-	-	-	-	-	-	-
COEAHMKE_01535	7.52e-140	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
COEAHMKE_01536	2.77e-114	flaR	-	-	F	-	-	-	topology modulation protein
COEAHMKE_01537	3.71e-95	-	-	-	-	-	-	-	-
COEAHMKE_01538	5.71e-262	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
COEAHMKE_01539	3.06e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
COEAHMKE_01540	5.69e-86	-	-	-	-	-	-	-	-
COEAHMKE_01541	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
COEAHMKE_01542	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
COEAHMKE_01543	1.44e-255	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
COEAHMKE_01544	6.46e-212	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
COEAHMKE_01545	7.77e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
COEAHMKE_01546	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
COEAHMKE_01547	1.72e-256	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
COEAHMKE_01548	5.4e-274	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
COEAHMKE_01549	1.29e-91	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
COEAHMKE_01550	1.13e-137	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
COEAHMKE_01551	1.07e-150	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
COEAHMKE_01552	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
COEAHMKE_01553	2.95e-146	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
COEAHMKE_01554	1.39e-148	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
COEAHMKE_01555	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
COEAHMKE_01556	3.49e-116	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
COEAHMKE_01557	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
COEAHMKE_01558	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
COEAHMKE_01559	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
COEAHMKE_01560	8.86e-214	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
COEAHMKE_01561	3.03e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
COEAHMKE_01562	4.69e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
COEAHMKE_01563	1.77e-238	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
COEAHMKE_01564	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
COEAHMKE_01565	3.94e-225	-	-	-	-	-	-	-	-
COEAHMKE_01566	1.83e-180	-	-	-	-	-	-	-	-
COEAHMKE_01567	7.35e-134	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
COEAHMKE_01568	7.83e-38	-	-	-	-	-	-	-	-
COEAHMKE_01569	1.4e-146	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
COEAHMKE_01570	3.03e-13	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
COEAHMKE_01571	1.19e-177	-	-	-	-	-	-	-	-
COEAHMKE_01572	2.79e-188	-	-	-	-	-	-	-	-
COEAHMKE_01573	5.57e-186	-	-	-	-	-	-	-	-
COEAHMKE_01574	3.13e-160	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
COEAHMKE_01575	7.06e-81	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
COEAHMKE_01576	6.01e-309	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
COEAHMKE_01577	3.45e-197	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
COEAHMKE_01578	7.43e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
COEAHMKE_01579	4.56e-89	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
COEAHMKE_01580	3.44e-160	-	-	-	S	-	-	-	Peptidase family M23
COEAHMKE_01581	2.88e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
COEAHMKE_01582	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
COEAHMKE_01583	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
COEAHMKE_01584	2.22e-229	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
COEAHMKE_01585	2.1e-151	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
COEAHMKE_01586	8.27e-191	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
COEAHMKE_01587	9.85e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
COEAHMKE_01588	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
COEAHMKE_01589	1.3e-201	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
COEAHMKE_01590	3.81e-173	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COEAHMKE_01591	8.1e-200	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
COEAHMKE_01592	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COEAHMKE_01593	3.98e-313	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
COEAHMKE_01594	3.92e-217	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
COEAHMKE_01595	5.68e-117	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
COEAHMKE_01596	3.67e-310	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
COEAHMKE_01597	9e-226	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
COEAHMKE_01598	1.11e-283	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
COEAHMKE_01599	4.32e-237	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
COEAHMKE_01600	3.44e-187	epsB	-	-	M	-	-	-	biosynthesis protein
COEAHMKE_01601	8.99e-162	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
COEAHMKE_01602	5.46e-185	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
COEAHMKE_01603	1.15e-155	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
COEAHMKE_01604	1.98e-133	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
COEAHMKE_01605	4.66e-57	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
COEAHMKE_01606	3.57e-84	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
COEAHMKE_01607	5.98e-77	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
COEAHMKE_01609	2.45e-47	-	-	-	S	-	-	-	Glycosyl transferase family 2
COEAHMKE_01610	3.35e-23	-	-	-	S	-	-	-	PFAM Glycosyl transferase family 2
COEAHMKE_01611	5.23e-174	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
COEAHMKE_01612	8.55e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
COEAHMKE_01613	1.03e-128	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
COEAHMKE_01614	9.65e-222	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
COEAHMKE_01615	2.96e-90	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
COEAHMKE_01616	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
COEAHMKE_01617	1.34e-196	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
COEAHMKE_01618	3.47e-85	-	-	-	S	-	-	-	Peptidase family M23
COEAHMKE_01619	4.9e-206	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
COEAHMKE_01620	1.95e-137	-	-	-	-	-	-	-	-
COEAHMKE_01621	3.13e-141	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
COEAHMKE_01622	1.53e-156	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
COEAHMKE_01623	2.35e-310	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
COEAHMKE_01624	1.21e-235	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
COEAHMKE_01625	6.18e-105	dltr	-	-	K	-	-	-	response regulator
COEAHMKE_01626	1.37e-62	sptS	-	-	T	-	-	-	Histidine kinase
COEAHMKE_01627	2.8e-147	sptS	-	-	T	-	-	-	Histidine kinase
COEAHMKE_01628	7.52e-264	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
COEAHMKE_01629	3.6e-92	-	-	-	O	-	-	-	OsmC-like protein
COEAHMKE_01630	2.48e-161	-	-	-	S	-	-	-	L-ascorbic acid biosynthetic process
COEAHMKE_01631	1.37e-138	-	-	-	-	-	-	-	-
COEAHMKE_01632	3.97e-109	-	-	-	-	-	-	-	-
COEAHMKE_01633	1.06e-73	-	-	-	-	-	-	-	-
COEAHMKE_01634	3.43e-51	-	-	-	-	-	-	-	-
COEAHMKE_01635	0.0	potE	-	-	E	-	-	-	Amino Acid
COEAHMKE_01636	2.3e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
COEAHMKE_01637	8.23e-249	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
COEAHMKE_01640	1.26e-117	-	-	-	-	-	-	-	-
COEAHMKE_01641	3.66e-310	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COEAHMKE_01642	9.13e-43	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
COEAHMKE_01643	2.55e-64	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
COEAHMKE_01644	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
COEAHMKE_01645	1.36e-203	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
COEAHMKE_01646	5.72e-284	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
COEAHMKE_01647	2.34e-127	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
COEAHMKE_01648	2.38e-143	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
COEAHMKE_01649	1.73e-24	-	-	-	K	-	-	-	Helix-turn-helix
COEAHMKE_01650	5.15e-24	-	-	-	K	-	-	-	Helix-turn-helix
COEAHMKE_01651	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
COEAHMKE_01652	1.22e-121	-	-	-	-	-	-	-	-
COEAHMKE_01653	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
COEAHMKE_01654	2.91e-229	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
COEAHMKE_01655	2.42e-238	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
COEAHMKE_01656	7.59e-123	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
COEAHMKE_01657	5.86e-106	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
COEAHMKE_01658	4.17e-111	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
COEAHMKE_01659	5.44e-88	yybA	-	-	K	-	-	-	Transcriptional regulator
COEAHMKE_01660	1.82e-18	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
COEAHMKE_01661	1.81e-88	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
COEAHMKE_01662	7.39e-311	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
COEAHMKE_01663	5.59e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COEAHMKE_01664	7.88e-219	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
COEAHMKE_01665	9.7e-133	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
COEAHMKE_01666	6.23e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
COEAHMKE_01667	4.53e-240	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
COEAHMKE_01668	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
COEAHMKE_01669	1.25e-241	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
COEAHMKE_01670	1.81e-29	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
COEAHMKE_01671	2.5e-59	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
COEAHMKE_01672	1.32e-184	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
COEAHMKE_01673	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
COEAHMKE_01674	9.54e-110	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
COEAHMKE_01675	2.71e-53	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
COEAHMKE_01676	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COEAHMKE_01677	1.39e-96	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
COEAHMKE_01678	2.11e-249	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COEAHMKE_01679	6.2e-54	dar	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
COEAHMKE_01680	2.99e-122	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
COEAHMKE_01681	2.4e-278	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
COEAHMKE_01682	4.24e-217	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
COEAHMKE_01683	1.54e-71	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
COEAHMKE_01686	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
COEAHMKE_01687	4.52e-140	vanZ	-	-	V	-	-	-	VanZ like family
COEAHMKE_01688	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COEAHMKE_01689	0.0	yclK	-	-	T	-	-	-	Histidine kinase
COEAHMKE_01690	4.46e-167	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
COEAHMKE_01691	8.14e-80	-	-	-	S	-	-	-	SdpI/YhfL protein family
COEAHMKE_01692	3.23e-221	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
COEAHMKE_01693	4.03e-286	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
COEAHMKE_01694	1.64e-40	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
COEAHMKE_01695	5.06e-46	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
COEAHMKE_01696	2.06e-289	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
COEAHMKE_01697	1.66e-221	-	-	-	-	-	-	-	-
COEAHMKE_01698	2.79e-77	lysM	-	-	M	-	-	-	LysM domain
COEAHMKE_01700	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
COEAHMKE_01701	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
COEAHMKE_01702	1.58e-33	-	-	-	-	-	-	-	-
COEAHMKE_01703	2.1e-236	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
COEAHMKE_01704	2.86e-39	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
COEAHMKE_01705	3.52e-252	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
COEAHMKE_01706	9.86e-160	cas4	3.1.12.1	-	L	ko:K07464	-	ko00000,ko01000,ko02048	Domain of unknown function DUF83
COEAHMKE_01707	5.5e-203	csd2	-	-	L	ko:K19115,ko:K19118	-	ko00000,ko02048	CRISPR-associated protein Cas7
COEAHMKE_01708	0.0	csd1	-	-	M	ko:K19117	-	ko00000,ko02048	CRISPR-associated protein (Cas_Csd1)
COEAHMKE_01709	1.11e-184	cas5	-	-	S	ko:K19119	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
COEAHMKE_01710	0.0	-	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
COEAHMKE_01711	1.4e-301	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
COEAHMKE_01712	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
COEAHMKE_01713	1.03e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
COEAHMKE_01714	1.26e-246	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
COEAHMKE_01715	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
COEAHMKE_01716	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COEAHMKE_01717	1.56e-154	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COEAHMKE_01718	1.27e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COEAHMKE_01719	1.19e-170	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
COEAHMKE_01720	6.62e-277	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
COEAHMKE_01721	3.23e-103	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
COEAHMKE_01722	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
COEAHMKE_01723	3.72e-159	-	-	-	C	-	-	-	Flavodoxin
COEAHMKE_01724	9.65e-193	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
COEAHMKE_01725	1.87e-68	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
COEAHMKE_01726	1.74e-28	-	-	-	-	-	-	-	-
COEAHMKE_01727	4.58e-248	-	-	-	S	-	-	-	Bacteriocin helveticin-J
COEAHMKE_01728	2.07e-47	-	-	-	M	-	-	-	Peptidase family M1 domain
COEAHMKE_01729	4.25e-176	-	-	-	M	-	-	-	Peptidase family M1 domain
COEAHMKE_01730	2.61e-76	-	-	-	M	-	-	-	Peptidase family M1 domain
COEAHMKE_01731	2.38e-225	-	-	-	S	-	-	-	SLAP domain
COEAHMKE_01732	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
COEAHMKE_01733	4.41e-282	-	-	-	S	-	-	-	SLAP domain
COEAHMKE_01734	1.24e-75	-	-	-	S	-	-	-	SLAP domain
COEAHMKE_01735	3.06e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COEAHMKE_01736	1.64e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
COEAHMKE_01737	7.82e-161	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
COEAHMKE_01738	1.26e-269	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
COEAHMKE_01739	9.02e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COEAHMKE_01740	6.86e-72	-	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
COEAHMKE_01741	2.77e-103	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
COEAHMKE_01742	6.03e-57	-	-	-	-	-	-	-	-
COEAHMKE_01743	2.68e-198	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
COEAHMKE_01744	1.44e-272	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
COEAHMKE_01745	9.45e-64	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
COEAHMKE_01746	1.16e-241	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
COEAHMKE_01747	0.0	yhaN	-	-	L	-	-	-	AAA domain
COEAHMKE_01748	2.37e-291	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
COEAHMKE_01749	8.43e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
COEAHMKE_01750	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
COEAHMKE_01751	4.21e-208	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
COEAHMKE_01752	3.87e-12	-	-	-	C	-	-	-	FMN-dependent dehydrogenase
COEAHMKE_01753	4.79e-173	mgtC3	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
COEAHMKE_01754	5.24e-180	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
COEAHMKE_01755	5.88e-72	-	-	-	-	-	-	-	-
COEAHMKE_01756	4.3e-190	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
COEAHMKE_01759	6.16e-198	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
COEAHMKE_01760	6.3e-110	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
COEAHMKE_01767	1.19e-279	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
COEAHMKE_01768	1.75e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
COEAHMKE_01769	4.59e-226	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COEAHMKE_01770	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COEAHMKE_01771	1.3e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
COEAHMKE_01772	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
COEAHMKE_01773	4.52e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
COEAHMKE_01774	2.62e-193	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
COEAHMKE_01775	4.16e-151	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
COEAHMKE_01776	5.73e-117	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
COEAHMKE_01777	1.24e-187	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
COEAHMKE_01778	2.55e-127	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
COEAHMKE_01779	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
COEAHMKE_01780	2.42e-74	-	-	-	-	-	-	-	-
COEAHMKE_01781	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
COEAHMKE_01782	6.84e-229	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
COEAHMKE_01783	2.37e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
COEAHMKE_01784	3.43e-68	-	-	-	-	-	-	-	-
COEAHMKE_01785	8.29e-173	-	-	-	-	-	-	-	-
COEAHMKE_01786	1.84e-170	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COEAHMKE_01787	1.41e-141	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
COEAHMKE_01788	4.62e-131	-	-	-	G	-	-	-	Aldose 1-epimerase
COEAHMKE_01789	1.06e-257	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
COEAHMKE_01790	3.19e-145	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
COEAHMKE_01791	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
COEAHMKE_01792	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
COEAHMKE_01793	2.21e-144	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
COEAHMKE_01794	2.86e-132	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
COEAHMKE_01795	3.29e-234	-	-	-	S	-	-	-	AAA domain
COEAHMKE_01796	3.29e-162	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COEAHMKE_01797	4.73e-31	-	-	-	-	-	-	-	-
COEAHMKE_01798	5.3e-209	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
COEAHMKE_01799	1.9e-161	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
COEAHMKE_01800	2e-44	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
COEAHMKE_01802	3.19e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COEAHMKE_01803	1.46e-239	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
COEAHMKE_01804	5.97e-106	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
COEAHMKE_01805	1.18e-55	-	-	-	-	-	-	-	-
COEAHMKE_01806	2.04e-95	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
COEAHMKE_01807	6.15e-66	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
COEAHMKE_01808	6.49e-223	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
COEAHMKE_01809	2.29e-227	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
COEAHMKE_01810	3.98e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
COEAHMKE_01811	5.73e-120	-	-	-	S	-	-	-	VanZ like family
COEAHMKE_01812	1.43e-141	-	-	-	K	-	-	-	WHG domain
COEAHMKE_01813	4.74e-51	-	-	-	-	-	-	-	-
COEAHMKE_01814	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
COEAHMKE_01815	4.83e-154	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
COEAHMKE_01816	2.26e-228	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
COEAHMKE_01817	5.69e-122	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
COEAHMKE_01818	4.23e-145	-	-	-	G	-	-	-	phosphoglycerate mutase
COEAHMKE_01819	5.44e-178	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
COEAHMKE_01820	2.06e-183	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
COEAHMKE_01821	1.35e-155	-	-	-	-	-	-	-	-
COEAHMKE_01822	3.84e-62	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
COEAHMKE_01823	2.97e-136	-	-	-	L	-	-	-	Integrase
COEAHMKE_01824	8.83e-57	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
COEAHMKE_01825	1.15e-67	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
COEAHMKE_01826	2.51e-89	-	-	-	-	-	-	-	-
COEAHMKE_01827	5.24e-159	-	-	-	S	-	-	-	MTH538 TIR-like domain (DUF1863)
COEAHMKE_01828	0.0	sthIR	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
COEAHMKE_01829	0.0	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
COEAHMKE_01830	6.71e-95	-	-	-	S	-	-	-	Protein of unknown function, DUF536
COEAHMKE_01831	1.28e-267	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
COEAHMKE_01832	9.12e-21	-	-	-	S	-	-	-	Enterocin A Immunity
COEAHMKE_01833	4.94e-49	-	-	-	S	-	-	-	Enterocin A Immunity
COEAHMKE_01834	8.68e-46	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
COEAHMKE_01835	8.68e-44	-	-	-	-	-	-	-	-
COEAHMKE_01836	4.7e-35	-	-	-	-	-	-	-	-
COEAHMKE_01837	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
COEAHMKE_01840	2.38e-176	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
COEAHMKE_01841	1.26e-214	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
COEAHMKE_01842	2.04e-27	-	-	-	-	-	-	-	-
COEAHMKE_01843	1.31e-121	-	-	-	-	-	-	-	-
COEAHMKE_01844	2.51e-31	-	-	-	S	-	-	-	Small integral membrane protein (DUF2273)
COEAHMKE_01845	6.49e-110	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
COEAHMKE_01846	3.42e-41	-	-	-	S	-	-	-	Transglycosylase associated protein
COEAHMKE_01847	1.14e-23	-	-	-	-	-	-	-	-
COEAHMKE_01848	3.46e-57	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
COEAHMKE_01849	2.14e-116	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
COEAHMKE_01850	5.84e-190	aspD	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	Aminotransferase
COEAHMKE_01851	1.9e-302	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
COEAHMKE_01852	8.48e-126	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
COEAHMKE_01853	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
COEAHMKE_01854	5.46e-95	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
COEAHMKE_01855	6.77e-87	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
COEAHMKE_01856	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
COEAHMKE_01857	5.78e-57	-	-	-	-	-	-	-	-
COEAHMKE_01858	7.09e-189	-	-	-	GK	-	-	-	ROK family
COEAHMKE_01859	1.04e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COEAHMKE_01860	2.06e-233	-	-	-	S	-	-	-	SLAP domain
COEAHMKE_01861	1e-305	-	-	-	-	-	-	-	-
COEAHMKE_01862	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
COEAHMKE_01863	1.28e-241	flp	-	-	V	-	-	-	Beta-lactamase
COEAHMKE_01864	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
COEAHMKE_01865	5.76e-54	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
COEAHMKE_01866	9.04e-87	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
COEAHMKE_01867	6.83e-84	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
COEAHMKE_01868	2.75e-09	-	-	-	-	-	-	-	-
COEAHMKE_01869	5.43e-111	tdh	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
COEAHMKE_01870	2.62e-104	tdh	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
COEAHMKE_01872	1.01e-20	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
COEAHMKE_01873	0.000256	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
COEAHMKE_01874	9.7e-304	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
COEAHMKE_01875	5.97e-56	mleR2	-	-	K	-	-	-	LysR substrate binding domain
COEAHMKE_01876	2.43e-18	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
COEAHMKE_01877	1.33e-88	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
COEAHMKE_01878	7.5e-308	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
COEAHMKE_01879	2.03e-73	-	-	-	-	-	-	-	-
COEAHMKE_01880	4.15e-48	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
COEAHMKE_01881	2.82e-152	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
COEAHMKE_01882	8.9e-51	-	-	-	-	-	-	-	-
COEAHMKE_01883	5.43e-133	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
COEAHMKE_01884	4.86e-120	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
COEAHMKE_01885	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
COEAHMKE_01886	4.77e-258	-	-	-	-	-	-	-	-
COEAHMKE_01887	2.1e-265	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
COEAHMKE_01888	1.3e-304	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
COEAHMKE_01889	5.93e-289	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
COEAHMKE_01890	1.47e-235	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
COEAHMKE_01891	2.46e-292	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
COEAHMKE_01892	4.54e-301	steT	-	-	E	ko:K03294	-	ko00000	amino acid
COEAHMKE_01893	2.77e-78	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
COEAHMKE_01894	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
COEAHMKE_01895	1.61e-92	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COEAHMKE_01896	1.71e-111	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COEAHMKE_01897	1.99e-271	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COEAHMKE_01898	9.88e-90	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
COEAHMKE_01899	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
COEAHMKE_01900	8.08e-205	-	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
COEAHMKE_01901	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
COEAHMKE_01902	3.09e-25	-	-	-	S	-	-	-	Protein of unknown function DUF262
COEAHMKE_01903	3.19e-62	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
COEAHMKE_01904	3.78e-56	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
COEAHMKE_01905	0.0	cadA	-	-	P	-	-	-	P-type ATPase
COEAHMKE_01906	1.75e-257	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
COEAHMKE_01907	9e-66	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
COEAHMKE_01908	5.58e-63	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
COEAHMKE_01909	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
COEAHMKE_01910	2.33e-101	-	-	-	S	-	-	-	Putative adhesin
COEAHMKE_01911	5.29e-199	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
COEAHMKE_01912	1.77e-61	-	-	-	-	-	-	-	-
COEAHMKE_01913	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
COEAHMKE_01914	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
COEAHMKE_01916	7.34e-22	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
COEAHMKE_01918	1.96e-19	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
COEAHMKE_01919	3.68e-54	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
COEAHMKE_01920	7.2e-56	-	-	-	-	-	-	-	-
COEAHMKE_01921	6.99e-70	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
COEAHMKE_01922	1.43e-308	-	-	-	L	-	-	-	Probable transposase
COEAHMKE_01923	1.41e-18	-	-	-	S	-	-	-	Fic/DOC family
COEAHMKE_01924	1.05e-228	lipA	-	-	I	-	-	-	Carboxylesterase family
COEAHMKE_01925	6.33e-87	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
COEAHMKE_01926	7.87e-37	-	-	-	-	-	-	-	-
COEAHMKE_01927	1.17e-79	-	-	-	S	-	-	-	Bacterial PH domain
COEAHMKE_01928	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
COEAHMKE_01929	9.88e-152	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
COEAHMKE_01930	5.9e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
COEAHMKE_01931	2.14e-185	-	-	-	F	-	-	-	Phosphorylase superfamily
COEAHMKE_01932	8.52e-125	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
COEAHMKE_01933	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
COEAHMKE_01934	1.54e-220	citR	-	-	K	-	-	-	Putative sugar-binding domain
COEAHMKE_01935	2.78e-67	-	-	-	-	-	-	-	-
COEAHMKE_01936	3.15e-22	-	-	-	-	-	-	-	-
COEAHMKE_01937	1.64e-86	-	-	-	S	-	-	-	Domain of unknown function DUF1828
COEAHMKE_01938	1.22e-121	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
COEAHMKE_01939	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
COEAHMKE_01940	1.27e-168	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
COEAHMKE_01941	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
COEAHMKE_01942	1.13e-125	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
COEAHMKE_01943	3.88e-140	-	-	-	S	-	-	-	SNARE associated Golgi protein
COEAHMKE_01944	4.19e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
COEAHMKE_01945	1.68e-163	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
COEAHMKE_01946	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
COEAHMKE_01947	1.27e-202	-	-	-	-	-	-	-	-
COEAHMKE_01948	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
COEAHMKE_01949	1.55e-308	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
COEAHMKE_01950	0.0	oatA	-	-	I	-	-	-	Acyltransferase
COEAHMKE_01951	6.09e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
COEAHMKE_01952	1.68e-183	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
COEAHMKE_01953	2.19e-40	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
COEAHMKE_01954	1.93e-149	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
COEAHMKE_01955	1.59e-212	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
COEAHMKE_01956	7.8e-266	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
COEAHMKE_01957	5.09e-283	-	-	-	KQ	-	-	-	helix_turn_helix, mercury resistance
COEAHMKE_01958	7.16e-139	-	-	-	S	-	-	-	KAP family P-loop domain
COEAHMKE_01959	4.14e-81	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
COEAHMKE_01960	7.68e-160	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
COEAHMKE_01961	6.78e-271	-	-	-	-	-	-	-	-
COEAHMKE_01964	7.06e-120	-	-	-	-	-	-	-	-
COEAHMKE_01965	0.0	slpX	-	-	S	-	-	-	SLAP domain
COEAHMKE_01966	3.16e-145	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
COEAHMKE_01967	4.12e-24	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
COEAHMKE_01969	2.25e-111	-	-	-	-	-	-	-	-
COEAHMKE_01970	4.88e-59	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
COEAHMKE_01971	8.29e-63	repA	-	-	S	-	-	-	Replication initiator protein A
COEAHMKE_01972	3.53e-92	repA	-	-	S	-	-	-	Replication initiator protein A
COEAHMKE_01973	1.46e-84	-	-	-	M	-	-	-	domain protein
COEAHMKE_01974	3.49e-115	-	-	-	M	-	-	-	YSIRK type signal peptide
COEAHMKE_01975	9.08e-21	-	-	-	M	-	-	-	domain protein
COEAHMKE_01976	2.71e-180	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
COEAHMKE_01977	2.26e-15	-	-	-	-	-	-	-	-
COEAHMKE_01978	1.29e-21	-	-	-	-	-	-	-	-
COEAHMKE_01979	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
COEAHMKE_01980	6.79e-152	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
COEAHMKE_01981	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
COEAHMKE_01982	1.99e-122	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
COEAHMKE_01983	3.7e-58	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
COEAHMKE_01984	1.05e-123	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
COEAHMKE_01985	2.53e-157	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
COEAHMKE_01986	9.72e-270	scrA5	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
COEAHMKE_01987	3.02e-17	scrA5	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
COEAHMKE_01988	2.35e-119	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
COEAHMKE_01989	9.85e-78	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
COEAHMKE_01990	3.73e-239	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
COEAHMKE_01991	5.16e-181	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
COEAHMKE_01992	3.51e-222	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
COEAHMKE_01993	2.76e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
COEAHMKE_01994	2.22e-133	-	-	-	K	-	-	-	Transcriptional regulator
COEAHMKE_01995	4.77e-29	-	-	-	K	-	-	-	Transcriptional regulator
COEAHMKE_01996	3.09e-107	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
COEAHMKE_01997	8.91e-306	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
COEAHMKE_01998	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
COEAHMKE_01999	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
COEAHMKE_02000	1.17e-61	-	-	-	-	-	-	-	-
COEAHMKE_02001	4.01e-134	-	-	-	E	-	-	-	amino acid
COEAHMKE_02002	1.57e-94	-	-	-	-	-	-	-	-
COEAHMKE_02003	9.74e-117	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
COEAHMKE_02004	7.46e-105	-	-	-	S	-	-	-	LPXTG cell wall anchor motif
COEAHMKE_02005	6.43e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COEAHMKE_02006	3.28e-175	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
COEAHMKE_02007	1.85e-48	-	-	-	-	-	-	-	-
COEAHMKE_02008	7.52e-95	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
COEAHMKE_02009	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
COEAHMKE_02010	0.0	-	-	-	S	-	-	-	TerB-C domain
COEAHMKE_02011	0.0	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
COEAHMKE_02012	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
COEAHMKE_02013	4.75e-80	-	-	-	-	-	-	-	-
COEAHMKE_02014	1.98e-179	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
COEAHMKE_02015	4.9e-11	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
COEAHMKE_02016	5.65e-60	-	-	-	C	-	-	-	FAD binding domain
COEAHMKE_02017	5.84e-32	-	-	-	C	-	-	-	FAD binding domain
COEAHMKE_02018	1.63e-87	-	-	-	C	-	-	-	FAD binding domain
COEAHMKE_02020	1.96e-164	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
COEAHMKE_02021	4.05e-290	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
COEAHMKE_02022	9.44e-77	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
COEAHMKE_02023	6.79e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
COEAHMKE_02024	1.52e-43	-	-	-	-	-	-	-	-
COEAHMKE_02025	4.63e-88	-	-	-	-	-	-	-	-
COEAHMKE_02026	1.56e-121	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
COEAHMKE_02027	5.1e-33	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
COEAHMKE_02028	5.26e-19	-	-	-	-	-	-	-	-
COEAHMKE_02029	3.08e-121	-	-	-	M	-	-	-	LysM domain protein
COEAHMKE_02030	6.81e-250	-	-	-	D	-	-	-	nuclear chromosome segregation
COEAHMKE_02031	2.67e-142	-	-	-	G	-	-	-	Phosphoglycerate mutase family
COEAHMKE_02032	4.43e-291	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
COEAHMKE_02033	1.46e-170	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
COEAHMKE_02034	4.98e-20	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
COEAHMKE_02035	2.38e-124	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
COEAHMKE_02036	4.19e-92	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
COEAHMKE_02037	2.04e-275	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
COEAHMKE_02038	1.09e-274	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
COEAHMKE_02039	5.43e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
COEAHMKE_02040	1.9e-61	-	-	-	-	-	-	-	-
COEAHMKE_02041	4.27e-22	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
COEAHMKE_02042	6.33e-231	-	-	-	L	-	-	-	Lactococcus lactis RepB C-terminus
COEAHMKE_02043	0.00083	-	-	-	-	-	-	-	-
COEAHMKE_02044	1.17e-148	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
COEAHMKE_02045	3.11e-67	-	-	-	S	-	-	-	YoeB-like toxin of bacterial type II toxin-antitoxin system
COEAHMKE_02046	8.84e-52	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
COEAHMKE_02047	1.72e-135	-	-	-	L	-	-	-	Integrase
COEAHMKE_02050	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
COEAHMKE_02051	0.0	-	-	-	E	-	-	-	Amino acid permease
COEAHMKE_02052	9.15e-73	-	-	-	-	-	-	-	-
COEAHMKE_02053	2.3e-128	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
COEAHMKE_02054	9.54e-74	-	-	-	-	-	-	-	-
COEAHMKE_02055	0.0	-	-	-	S	-	-	-	ABC transporter
COEAHMKE_02056	1.14e-177	-	-	-	S	-	-	-	Putative threonine/serine exporter
COEAHMKE_02057	1.43e-106	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
COEAHMKE_02058	2.72e-101	-	-	-	-	-	-	-	-
COEAHMKE_02059	9.24e-140	-	-	-	L	-	-	-	Integrase
COEAHMKE_02060	2.22e-59	-	-	-	T	ko:K07172	-	ko00000,ko02048	Antidote-toxin recognition MazE, bacterial antitoxin
COEAHMKE_02061	3.2e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
COEAHMKE_02062	3.3e-53	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
COEAHMKE_02063	7.66e-245	-	-	-	M	-	-	-	Glycosyl transferase family group 2
COEAHMKE_02065	1.52e-68	-	-	-	-	-	-	-	-
COEAHMKE_02066	1.02e-101	-	-	-	-	-	-	-	-
COEAHMKE_02069	4.82e-55	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
COEAHMKE_02070	2.41e-314	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
COEAHMKE_02071	5.51e-69	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
COEAHMKE_02072	1.73e-199	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
COEAHMKE_02075	1.32e-270	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
COEAHMKE_02076	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
COEAHMKE_02077	2.29e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
COEAHMKE_02078	1.02e-238	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
COEAHMKE_02079	3.96e-190	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
COEAHMKE_02080	2.06e-157	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
COEAHMKE_02081	7.28e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
COEAHMKE_02082	8.05e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
COEAHMKE_02083	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
COEAHMKE_02084	1.85e-58	-	-	-	-	-	-	-	-
COEAHMKE_02085	4.14e-100	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
COEAHMKE_02086	4.45e-83	-	-	-	-	-	-	-	-
COEAHMKE_02088	3.74e-154	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
COEAHMKE_02089	1.51e-185	-	-	-	F	-	-	-	Phosphorylase superfamily
COEAHMKE_02090	6.15e-68	codA	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
COEAHMKE_02092	2.51e-103	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
COEAHMKE_02093	1.23e-72	-	-	-	-	-	-	-	-
COEAHMKE_02094	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COEAHMKE_02095	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COEAHMKE_02096	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
COEAHMKE_02097	7.84e-106	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
COEAHMKE_02100	3.94e-37	-	-	-	-	-	-	-	-
COEAHMKE_02102	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
COEAHMKE_02103	4.78e-249	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COEAHMKE_02104	5.97e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
COEAHMKE_02105	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COEAHMKE_02106	2.52e-309	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
COEAHMKE_02107	5.19e-78	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
COEAHMKE_02108	3.06e-77	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
COEAHMKE_02109	1.26e-46	yabO	-	-	J	-	-	-	S4 domain protein
COEAHMKE_02110	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
COEAHMKE_02111	6.33e-133	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
COEAHMKE_02112	3.42e-233	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
COEAHMKE_02113	2.39e-164	-	-	-	S	-	-	-	(CBS) domain
COEAHMKE_02114	5.87e-120	-	-	-	K	-	-	-	transcriptional regulator
COEAHMKE_02115	3.26e-276	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
COEAHMKE_02116	6.61e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
COEAHMKE_02117	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
COEAHMKE_02118	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
COEAHMKE_02119	6.18e-52	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
COEAHMKE_02120	8.44e-199	yhaX	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
COEAHMKE_02121	2.37e-32	-	-	-	E	-	-	-	amino acid
COEAHMKE_02122	4.87e-238	-	-	-	E	-	-	-	amino acid
COEAHMKE_02123	2.62e-55	-	-	-	E	-	-	-	amino acid
COEAHMKE_02124	2.58e-293	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
COEAHMKE_02125	5.98e-208	-	-	-	-	-	-	-	-
COEAHMKE_02126	3.15e-182	-	-	-	D	-	-	-	ftsk spoiiie
COEAHMKE_02130	0.0	-	-	-	V	-	-	-	DNA restriction-modification system
COEAHMKE_02131	1.59e-139	-	-	-	-	-	-	-	-
COEAHMKE_02132	1.48e-26	-	-	-	-	-	-	-	-
COEAHMKE_02133	1.96e-23	-	-	-	-	-	-	-	-
COEAHMKE_02134	1.52e-74	-	-	-	-	-	-	-	-
COEAHMKE_02135	1.31e-10	-	-	-	-	-	-	-	-
COEAHMKE_02137	8.71e-149	-	-	-	S	-	-	-	SLAP domain
COEAHMKE_02138	2.49e-114	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
COEAHMKE_02139	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
COEAHMKE_02140	6.1e-213	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
COEAHMKE_02141	1.28e-37	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
COEAHMKE_02142	2.73e-285	-	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
COEAHMKE_02145	2.32e-166	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
COEAHMKE_02146	4.18e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
COEAHMKE_02147	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
COEAHMKE_02148	2.33e-267	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
COEAHMKE_02150	1.56e-188	idhA	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COEAHMKE_02151	2e-99	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
COEAHMKE_02152	2.07e-201	is18	-	-	L	-	-	-	Integrase core domain
COEAHMKE_02153	8.34e-51	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
COEAHMKE_02154	7.66e-97	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
COEAHMKE_02155	5.96e-36	-	-	-	S	-	-	-	Glycosyl transferase family 11
COEAHMKE_02156	5.73e-66	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
COEAHMKE_02159	2.11e-29	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
COEAHMKE_02160	1.97e-257	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
COEAHMKE_02161	1.98e-32	epsJ	-	-	M	-	-	-	Glycosyltransferase group 2 family protein
COEAHMKE_02162	2.84e-30	-	-	-	S	-	-	-	Fic/DOC family
COEAHMKE_02163	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
COEAHMKE_02164	3.09e-286	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
COEAHMKE_02165	3.63e-33	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
COEAHMKE_02166	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
COEAHMKE_02167	5.24e-41	-	-	-	-	-	-	-	-
COEAHMKE_02168	4.45e-122	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
COEAHMKE_02169	1.49e-121	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
COEAHMKE_02170	3.7e-38	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
COEAHMKE_02171	7.98e-73	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
COEAHMKE_02172	9.06e-90	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
COEAHMKE_02173	2.9e-275	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
COEAHMKE_02174	1.02e-196	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, C-terminal domain
COEAHMKE_02175	2.64e-66	-	-	-	-	-	-	-	-
COEAHMKE_02176	1.69e-09	-	-	-	-	-	-	-	-
COEAHMKE_02177	6.53e-77	mobC	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
COEAHMKE_02178	9.71e-261	-	-	-	D	-	-	-	Relaxase/Mobilisation nuclease domain
COEAHMKE_02179	6.92e-141	-	-	-	-	-	-	-	-
COEAHMKE_02180	3.52e-80	-	-	-	D	-	-	-	Fic/DOC family