ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HHIGLKPN_00002 4.09e-103 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HHIGLKPN_00003 3.18e-50 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
HHIGLKPN_00004 6.21e-41 axe - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
HHIGLKPN_00005 7.97e-222 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HHIGLKPN_00006 5.2e-125 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HHIGLKPN_00007 9.26e-317 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HHIGLKPN_00008 1e-220 - - - K - - - helix_turn_helix, arabinose operon control protein
HHIGLKPN_00009 3.97e-46 - - - L ko:K07497 - ko00000 hmm pf00665
HHIGLKPN_00010 6.33e-46 - - - L ko:K07497 - ko00000 hmm pf00665
HHIGLKPN_00011 1.13e-76 - - - L ko:K07497 - ko00000 hmm pf00665
HHIGLKPN_00012 2.28e-145 - - - L - - - Helix-turn-helix domain
HHIGLKPN_00013 1.92e-206 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HHIGLKPN_00014 1.43e-125 lemA - - S ko:K03744 - ko00000 LemA family
HHIGLKPN_00015 1.78e-244 ysdE - - P - - - Citrate transporter
HHIGLKPN_00016 1.8e-91 - - - S - - - Iron-sulphur cluster biosynthesis
HHIGLKPN_00017 2.48e-84 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
HHIGLKPN_00018 1.21e-299 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
HHIGLKPN_00019 9.69e-25 - - - - - - - -
HHIGLKPN_00020 4.03e-157 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
HHIGLKPN_00021 2.79e-206 - - - L - - - HNH nucleases
HHIGLKPN_00022 7.41e-176 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HHIGLKPN_00023 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HHIGLKPN_00024 1.71e-156 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HHIGLKPN_00025 6.81e-83 yeaO - - S - - - Protein of unknown function, DUF488
HHIGLKPN_00026 4.26e-160 terC - - P - - - Integral membrane protein TerC family
HHIGLKPN_00027 1.71e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
HHIGLKPN_00028 1.14e-166 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
HHIGLKPN_00029 1.14e-111 - - - - - - - -
HHIGLKPN_00030 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHIGLKPN_00031 3.27e-228 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HHIGLKPN_00032 4.17e-187 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHIGLKPN_00033 2.84e-184 - - - S - - - Protein of unknown function (DUF1002)
HHIGLKPN_00034 3.74e-204 epsV - - S - - - glycosyl transferase family 2
HHIGLKPN_00035 1.07e-163 - - - S - - - Alpha/beta hydrolase family
HHIGLKPN_00036 5.93e-149 - - - GM - - - NmrA-like family
HHIGLKPN_00037 6.35e-73 - - - - - - - -
HHIGLKPN_00038 8.37e-232 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHIGLKPN_00039 4.46e-156 - - - K - - - Bacterial regulatory proteins, tetR family
HHIGLKPN_00040 4.16e-173 - - - - - - - -
HHIGLKPN_00041 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HHIGLKPN_00042 3.68e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HHIGLKPN_00043 2.69e-295 - - - S - - - Cysteine-rich secretory protein family
HHIGLKPN_00044 7.25e-265 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HHIGLKPN_00045 1.75e-151 - - - - - - - -
HHIGLKPN_00046 2.2e-254 yibE - - S - - - overlaps another CDS with the same product name
HHIGLKPN_00047 5.49e-167 yibF - - S - - - overlaps another CDS with the same product name
HHIGLKPN_00048 4.03e-200 - - - I - - - alpha/beta hydrolase fold
HHIGLKPN_00049 3.6e-42 - - - - - - - -
HHIGLKPN_00050 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
HHIGLKPN_00051 8.67e-111 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
HHIGLKPN_00052 2.55e-111 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HHIGLKPN_00053 2.4e-189 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HHIGLKPN_00054 1.6e-113 usp5 - - T - - - universal stress protein
HHIGLKPN_00056 5.12e-197 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
HHIGLKPN_00057 2.12e-178 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HHIGLKPN_00058 3.54e-165 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHIGLKPN_00059 4.13e-187 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHIGLKPN_00060 3.79e-141 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HHIGLKPN_00061 8.26e-106 - - - - - - - -
HHIGLKPN_00062 0.0 - - - S - - - Calcineurin-like phosphoesterase
HHIGLKPN_00063 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HHIGLKPN_00064 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
HHIGLKPN_00067 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
HHIGLKPN_00068 1.35e-180 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HHIGLKPN_00069 6.51e-128 yitW - - S - - - Iron-sulfur cluster assembly protein
HHIGLKPN_00070 4.09e-292 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
HHIGLKPN_00071 1.42e-287 yttB - - EGP - - - Major Facilitator
HHIGLKPN_00072 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HHIGLKPN_00073 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HHIGLKPN_00074 4.38e-103 - - - - - - - -
HHIGLKPN_00075 1.29e-14 - - - - - - - -
HHIGLKPN_00076 9.97e-40 - - - - - - - -
HHIGLKPN_00077 7.43e-50 - - - S - - - Protein of unknown function (DUF2922)
HHIGLKPN_00078 8.28e-233 - - - S - - - SLAP domain
HHIGLKPN_00080 9.59e-11 - - - K - - - DNA-templated transcription, initiation
HHIGLKPN_00081 1.89e-34 - - - K - - - DNA-templated transcription, initiation
HHIGLKPN_00082 1.05e-124 - - - - - - - -
HHIGLKPN_00083 1.12e-285 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HHIGLKPN_00084 1.42e-268 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
HHIGLKPN_00085 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
HHIGLKPN_00086 4.01e-119 - - - K - - - Protein of unknown function (DUF4065)
HHIGLKPN_00087 1.56e-228 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HHIGLKPN_00088 4.31e-152 - - - - - - - -
HHIGLKPN_00089 8.29e-173 - - - - - - - -
HHIGLKPN_00090 1.84e-170 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HHIGLKPN_00091 1.41e-141 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HHIGLKPN_00092 4.62e-131 - - - G - - - Aldose 1-epimerase
HHIGLKPN_00093 1.06e-257 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HHIGLKPN_00094 3.19e-145 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HHIGLKPN_00095 0.0 XK27_08315 - - M - - - Sulfatase
HHIGLKPN_00096 0.0 - - - S - - - Fibronectin type III domain
HHIGLKPN_00097 6.28e-310 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HHIGLKPN_00098 1.85e-28 - - - - - - - -
HHIGLKPN_00100 0.0 pepC1 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
HHIGLKPN_00101 4e-152 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HHIGLKPN_00102 3.09e-267 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HHIGLKPN_00103 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
HHIGLKPN_00104 1.75e-95 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HHIGLKPN_00105 1.57e-97 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HHIGLKPN_00106 6.33e-148 - - - - - - - -
HHIGLKPN_00108 2.55e-148 - - - E - - - Belongs to the SOS response-associated peptidase family
HHIGLKPN_00109 2.35e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HHIGLKPN_00110 6.34e-118 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
HHIGLKPN_00111 4.07e-141 - - - S ko:K06872 - ko00000 TPM domain
HHIGLKPN_00112 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
HHIGLKPN_00113 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HHIGLKPN_00114 3.86e-189 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
HHIGLKPN_00115 2.1e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HHIGLKPN_00116 6.96e-207 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HHIGLKPN_00117 3.35e-51 veg - - S - - - Biofilm formation stimulator VEG
HHIGLKPN_00118 3.54e-191 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HHIGLKPN_00119 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HHIGLKPN_00120 6.32e-118 - - - S - - - SLAP domain
HHIGLKPN_00122 2.76e-214 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HHIGLKPN_00125 4.32e-279 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HHIGLKPN_00126 0.0 mdr - - EGP - - - Major Facilitator
HHIGLKPN_00127 3.25e-190 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HHIGLKPN_00128 1.04e-152 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HHIGLKPN_00129 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HHIGLKPN_00130 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HHIGLKPN_00131 4.49e-233 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
HHIGLKPN_00132 1.89e-118 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
HHIGLKPN_00133 3.47e-73 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
HHIGLKPN_00134 8.9e-66 - - - - - - - -
HHIGLKPN_00135 4.04e-267 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HHIGLKPN_00136 2.12e-110 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HHIGLKPN_00137 1.26e-87 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HHIGLKPN_00138 8.59e-85 - - - M - - - LPXTG-motif cell wall anchor domain protein
HHIGLKPN_00139 4.81e-21 - - - M - - - LPXTG-motif cell wall anchor domain protein
HHIGLKPN_00140 8.77e-42 - - - M - - - LPXTG-motif cell wall anchor domain protein
HHIGLKPN_00141 1.92e-28 - - - - - - - -
HHIGLKPN_00142 2.66e-48 - - - CO ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin
HHIGLKPN_00143 2.51e-152 - - - K - - - Rhodanese Homology Domain
HHIGLKPN_00144 7.66e-222 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HHIGLKPN_00145 1.2e-48 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
HHIGLKPN_00146 6.32e-35 - - - S - - - PD-(D/E)XK nuclease family transposase
HHIGLKPN_00147 4.56e-93 - - - S - - - Uncharacterised protein family (UPF0236)
HHIGLKPN_00148 4.39e-177 yxeH - - S - - - hydrolase
HHIGLKPN_00149 2.66e-48 - - - S - - - Enterocin A Immunity
HHIGLKPN_00150 4.62e-284 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
HHIGLKPN_00151 7.41e-65 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
HHIGLKPN_00153 2.11e-309 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HHIGLKPN_00154 4.31e-195 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HHIGLKPN_00155 9.06e-159 - - - M - - - ErfK YbiS YcfS YnhG
HHIGLKPN_00156 2.93e-119 - - - K - - - Virulence activator alpha C-term
HHIGLKPN_00157 1.03e-133 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
HHIGLKPN_00158 2.74e-145 - - - S - - - PD-(D/E)XK nuclease family transposase
HHIGLKPN_00159 5.02e-20 - - - S - - - PD-(D/E)XK nuclease family transposase
HHIGLKPN_00160 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HHIGLKPN_00161 5.16e-218 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
HHIGLKPN_00162 5.94e-118 - - - L - - - NUDIX domain
HHIGLKPN_00163 3.27e-53 - - - - - - - -
HHIGLKPN_00164 1.66e-42 - - - - - - - -
HHIGLKPN_00166 1.56e-231 - - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HHIGLKPN_00167 1.74e-142 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HHIGLKPN_00168 1.13e-182 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HHIGLKPN_00170 8.71e-149 - - - S - - - SLAP domain
HHIGLKPN_00172 1.31e-10 - - - - - - - -
HHIGLKPN_00173 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HHIGLKPN_00175 3.59e-17 - - - S - - - Adenine-specific methyltransferase EcoRI
HHIGLKPN_00177 5.15e-154 - - - S ko:K07507 - ko00000,ko02000 MgtC family
HHIGLKPN_00178 1.64e-304 - - - I - - - Protein of unknown function (DUF2974)
HHIGLKPN_00179 5.32e-35 - - - S - - - Transglycosylase associated protein
HHIGLKPN_00180 1.9e-15 - - - S - - - CsbD-like
HHIGLKPN_00181 1.39e-96 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
HHIGLKPN_00182 2.11e-249 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHIGLKPN_00183 2.99e-107 dar 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
HHIGLKPN_00184 5.19e-95 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HHIGLKPN_00185 1.96e-98 - - - K - - - LytTr DNA-binding domain
HHIGLKPN_00186 9.74e-98 - - - S - - - Protein of unknown function (DUF3021)
HHIGLKPN_00187 9e-189 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HHIGLKPN_00188 1.43e-117 - - - S ko:K01992 - ko00000,ko00002,ko02000 domain protein
HHIGLKPN_00189 1.57e-239 - - - S - - - Bacteriocin helveticin-J
HHIGLKPN_00190 5.42e-310 slpX - - S - - - SLAP domain
HHIGLKPN_00191 2.17e-43 - - - L - - - Integrase
HHIGLKPN_00192 2.28e-149 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
HHIGLKPN_00193 6.61e-266 - - - EGP - - - Major facilitator Superfamily
HHIGLKPN_00194 1.9e-11 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
HHIGLKPN_00195 1.85e-58 - - - - - - - -
HHIGLKPN_00196 7.16e-101 - - - S - - - Domain of unknown function (DUF5067)
HHIGLKPN_00197 4.45e-83 - - - - - - - -
HHIGLKPN_00198 4.1e-64 - - - - - - - -
HHIGLKPN_00199 1.02e-183 - - - F - - - Phosphorylase superfamily
HHIGLKPN_00200 6.33e-293 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HHIGLKPN_00201 4.43e-32 - - - K - - - helix_turn_helix, mercury resistance
HHIGLKPN_00202 3.49e-108 - - - K - - - helix_turn_helix, mercury resistance
HHIGLKPN_00203 1.34e-47 - - - F - - - nucleoside 2-deoxyribosyltransferase
HHIGLKPN_00204 6.29e-12 fabZ 3.5.1.108, 4.2.1.59 - IM ko:K16363 ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 FabA-like domain
HHIGLKPN_00205 8.45e-92 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HHIGLKPN_00206 3.62e-246 pbpX1 - - V - - - Beta-lactamase
HHIGLKPN_00207 0.0 - - - L - - - Helicase C-terminal domain protein
HHIGLKPN_00208 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
HHIGLKPN_00209 1.25e-204 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HHIGLKPN_00210 3.94e-117 - - - G - - - Phosphotransferase enzyme family
HHIGLKPN_00211 1.19e-85 - - - G - - - Phosphotransferase enzyme family
HHIGLKPN_00212 7.58e-244 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHIGLKPN_00213 3.62e-73 - - - - - - - -
HHIGLKPN_00214 0.0 nisT - - V ko:K06147,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC transporter
HHIGLKPN_00215 1.29e-196 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 haloacid dehalogenase-like hydrolase
HHIGLKPN_00216 0.0 fusA1 - - J - - - elongation factor G
HHIGLKPN_00217 8.57e-211 yvgN - - C - - - Aldo keto reductase
HHIGLKPN_00218 6.52e-270 - - - S - - - SLAP domain
HHIGLKPN_00219 6.05e-19 - - - S - - - Bacteriocin helveticin-J
HHIGLKPN_00220 1.4e-172 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HHIGLKPN_00221 1.05e-226 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HHIGLKPN_00222 1.17e-168 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HHIGLKPN_00223 4.47e-178 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HHIGLKPN_00224 2.4e-68 - - - - - - - -
HHIGLKPN_00225 4.97e-24 - - - - - - - -
HHIGLKPN_00226 3.93e-134 - - - E - - - GDSL-like Lipase/Acylhydrolase
HHIGLKPN_00227 2.43e-223 ydbI - - K - - - AI-2E family transporter
HHIGLKPN_00228 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
HHIGLKPN_00229 4.63e-78 - - - S - - - Domain of unknown function (DUF4430)
HHIGLKPN_00230 6.12e-112 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
HHIGLKPN_00231 3.65e-128 - - - S - - - Cob(I)alamin adenosyltransferase
HHIGLKPN_00232 5.71e-192 - - - S - - - Putative ABC-transporter type IV
HHIGLKPN_00233 3.64e-307 - - - S - - - LPXTG cell wall anchor motif
HHIGLKPN_00234 1.59e-73 - - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HHIGLKPN_00235 6.5e-63 vsr - - L ko:K07458 - ko00000,ko01000,ko03400 DNA mismatch endonuclease Vsr
HHIGLKPN_00236 6.65e-186 dcm 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
HHIGLKPN_00237 3.87e-261 - - - V - - - Z1 domain
HHIGLKPN_00238 3.46e-129 - - - L - - - NgoFVII restriction endonuclease
HHIGLKPN_00239 2.01e-134 - - - K - - - Bacterial regulatory proteins, tetR family
HHIGLKPN_00240 5.09e-28 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HHIGLKPN_00241 1.96e-192 - - - K ko:K09705 - ko00000 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HHIGLKPN_00242 6.16e-98 yngC - - S - - - SNARE associated Golgi protein
HHIGLKPN_00243 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
HHIGLKPN_00244 0.0 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HHIGLKPN_00245 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative DNA-binding domain
HHIGLKPN_00246 2.19e-124 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
HHIGLKPN_00247 7.67e-234 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
HHIGLKPN_00249 6.71e-78 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHIGLKPN_00250 3.55e-173 - - - K ko:K03492 - ko00000,ko03000 UTRA
HHIGLKPN_00251 3e-308 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
HHIGLKPN_00252 4.18e-197 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HHIGLKPN_00253 8.44e-81 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
HHIGLKPN_00254 1.96e-77 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
HHIGLKPN_00255 1.21e-115 - - - L - - - COG3547 Transposase and inactivated derivatives
HHIGLKPN_00256 3.43e-110 - - - K - - - Helix-turn-helix XRE-family like proteins
HHIGLKPN_00257 2.55e-61 - - - K - - - Helix-turn-helix XRE-family like proteins
HHIGLKPN_00259 6.15e-156 - - - - - - - -
HHIGLKPN_00261 6.83e-105 - - - S - - - Protein of unknown function (DUF3232)
HHIGLKPN_00262 0.0 - - - S - - - SLAP domain
HHIGLKPN_00263 3.02e-171 - - - K - - - Helix-turn-helix XRE-family like proteins
HHIGLKPN_00264 5.05e-115 - - - - - - - -
HHIGLKPN_00265 3.48e-26 - - - - - - - -
HHIGLKPN_00266 9.39e-85 - - - - - - - -
HHIGLKPN_00267 3.53e-32 - - - K - - - Helix-turn-helix XRE-family like proteins
HHIGLKPN_00268 1.05e-163 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HHIGLKPN_00269 9.55e-125 - - - K - - - Helix-turn-helix domain
HHIGLKPN_00270 9.32e-293 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HHIGLKPN_00271 3.03e-277 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HHIGLKPN_00272 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HHIGLKPN_00273 8.8e-142 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HHIGLKPN_00274 1.83e-106 - - - S - - - Protein of unknown function (DUF1694)
HHIGLKPN_00275 2.28e-307 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HHIGLKPN_00276 4.53e-55 - - - - - - - -
HHIGLKPN_00277 2.71e-103 uspA - - T - - - universal stress protein
HHIGLKPN_00278 1.38e-274 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HHIGLKPN_00279 8.85e-47 - - - S - - - Protein of unknown function (DUF2969)
HHIGLKPN_00280 1.31e-67 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
HHIGLKPN_00281 1.68e-227 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
HHIGLKPN_00282 1.21e-40 - - - S - - - Protein of unknown function (DUF1146)
HHIGLKPN_00283 1.14e-90 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HHIGLKPN_00284 1.74e-316 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HHIGLKPN_00285 6.45e-216 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HHIGLKPN_00286 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HHIGLKPN_00287 1.38e-121 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHIGLKPN_00288 5.39e-83 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HHIGLKPN_00289 4.83e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHIGLKPN_00290 4.82e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HHIGLKPN_00291 2.15e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HHIGLKPN_00292 7.56e-242 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HHIGLKPN_00293 3.44e-200 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HHIGLKPN_00294 7.36e-234 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HHIGLKPN_00295 4.94e-146 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HHIGLKPN_00296 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
HHIGLKPN_00299 6.05e-250 ampC - - V - - - Beta-lactamase
HHIGLKPN_00300 2.87e-52 - - - EGP - - - Major Facilitator
HHIGLKPN_00301 2.61e-193 - - - EGP - - - Major Facilitator
HHIGLKPN_00302 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
HHIGLKPN_00303 1.87e-203 - - - E - - - Amino acid permease
HHIGLKPN_00304 2.14e-121 - - - E - - - Amino acid permease
HHIGLKPN_00305 5.62e-28 - - - C - - - Pyridoxamine 5'-phosphate oxidase
HHIGLKPN_00306 6.06e-112 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HHIGLKPN_00307 5.6e-65 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HHIGLKPN_00308 2.66e-57 - - - S - - - Enterocin A Immunity
HHIGLKPN_00311 9.88e-39 - - - C - - - Pyridoxamine 5'-phosphate oxidase
HHIGLKPN_00312 2.08e-84 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHIGLKPN_00313 6.91e-84 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHIGLKPN_00314 1.64e-108 - - - L - - - Integrase
HHIGLKPN_00315 2.61e-195 - - - L - - - Phage integrase, N-terminal SAM-like domain
HHIGLKPN_00316 1.34e-200 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
HHIGLKPN_00317 1.87e-104 - - - M - - - Glycosyl transferases group 1
HHIGLKPN_00318 7.77e-34 - - - K - - - Helix-turn-helix domain
HHIGLKPN_00319 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHIGLKPN_00320 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHIGLKPN_00321 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HHIGLKPN_00322 7.84e-106 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HHIGLKPN_00325 3.72e-35 - - - - - - - -
HHIGLKPN_00327 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HHIGLKPN_00328 4.78e-249 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHIGLKPN_00329 5.97e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HHIGLKPN_00330 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HHIGLKPN_00331 1.46e-308 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HHIGLKPN_00332 5.19e-78 - - - J ko:K07571 - ko00000 S1 RNA binding domain
HHIGLKPN_00333 3.06e-77 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HHIGLKPN_00334 1.26e-46 yabO - - J - - - S4 domain protein
HHIGLKPN_00335 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HHIGLKPN_00336 1.55e-133 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HHIGLKPN_00337 3.42e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HHIGLKPN_00338 2.39e-164 - - - S - - - (CBS) domain
HHIGLKPN_00339 2.05e-120 - - - K - - - transcriptional regulator
HHIGLKPN_00340 3.26e-276 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HHIGLKPN_00341 6.61e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HHIGLKPN_00342 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HHIGLKPN_00343 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HHIGLKPN_00344 6.18e-52 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HHIGLKPN_00345 8.44e-199 yhaX - - S - - - Sucrose-6F-phosphate phosphohydrolase
HHIGLKPN_00346 2.37e-32 - - - E - - - amino acid
HHIGLKPN_00347 1.77e-244 - - - E - - - amino acid
HHIGLKPN_00348 2.62e-55 - - - E - - - amino acid
HHIGLKPN_00349 9e-294 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HHIGLKPN_00350 6.84e-149 - - - - - - - -
HHIGLKPN_00352 2.58e-155 - - - S - - - Protein of unknown function DUF262
HHIGLKPN_00353 1.6e-22 - - - L - - - helicase
HHIGLKPN_00354 4.98e-67 - - - L - - - Transposase and inactivated derivatives, IS30 family
HHIGLKPN_00356 9.47e-20 - - - - - - - -
HHIGLKPN_00357 2.98e-197 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
HHIGLKPN_00358 1.77e-87 - - - L - - - Transposase and inactivated derivatives, IS30 family
HHIGLKPN_00359 2.71e-192 - - - S - - - Protein of unknown function (DUF2974)
HHIGLKPN_00360 1.66e-137 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HHIGLKPN_00361 3.66e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HHIGLKPN_00362 9.06e-192 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HHIGLKPN_00363 8.97e-170 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HHIGLKPN_00364 7.36e-22 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
HHIGLKPN_00365 3.85e-105 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
HHIGLKPN_00366 6.26e-79 - - - EGP - - - Major facilitator superfamily
HHIGLKPN_00367 5.28e-118 - - - EGP - - - Major facilitator superfamily
HHIGLKPN_00368 1.47e-130 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HHIGLKPN_00369 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
HHIGLKPN_00370 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HHIGLKPN_00371 1.03e-103 - - - K - - - Transcriptional regulator, MarR family
HHIGLKPN_00372 1.75e-189 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HHIGLKPN_00373 6.43e-167 - - - F - - - glutamine amidotransferase
HHIGLKPN_00374 3.05e-190 - - - - - - - -
HHIGLKPN_00375 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
HHIGLKPN_00376 1.53e-266 pepA - - E - - - M42 glutamyl aminopeptidase
HHIGLKPN_00377 2.61e-40 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
HHIGLKPN_00378 1.09e-213 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
HHIGLKPN_00379 0.0 qacA - - EGP - - - Major Facilitator
HHIGLKPN_00380 4.47e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HHIGLKPN_00381 1.47e-301 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
HHIGLKPN_00382 9.81e-197 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
HHIGLKPN_00383 5.59e-39 - 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
HHIGLKPN_00384 1.01e-99 - 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HHIGLKPN_00385 1.1e-93 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
HHIGLKPN_00386 3.8e-60 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
HHIGLKPN_00387 5.6e-186 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
HHIGLKPN_00388 1.76e-109 - - - K - - - acetyltransferase
HHIGLKPN_00389 2.7e-190 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HHIGLKPN_00390 6.78e-208 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HHIGLKPN_00391 1.52e-119 - - - K - - - Bacterial regulatory proteins, tetR family
HHIGLKPN_00392 6.13e-315 qacA - - EGP - - - Major Facilitator
HHIGLKPN_00397 1.04e-124 - - - K - - - Acetyltransferase (GNAT) domain
HHIGLKPN_00398 6.69e-81 - - - - - - - -
HHIGLKPN_00399 2.87e-118 - - - L - - - helicase activity
HHIGLKPN_00401 1.16e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HHIGLKPN_00402 2.6e-145 - - - L - - - COG3547 Transposase and inactivated derivatives
HHIGLKPN_00403 4.85e-46 - - - KLT - - - serine threonine protein kinase
HHIGLKPN_00404 1.06e-111 - - - L - - - Resolvase, N terminal domain
HHIGLKPN_00405 1.01e-74 - - - - - - - -
HHIGLKPN_00406 0.0 - - - E - - - Amino acid permease
HHIGLKPN_00407 2.41e-235 ybcH - - D ko:K06889 - ko00000 Alpha beta
HHIGLKPN_00408 5.08e-304 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HHIGLKPN_00409 3.09e-26 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HHIGLKPN_00410 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HHIGLKPN_00411 1.16e-184 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HHIGLKPN_00412 5.85e-274 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HHIGLKPN_00413 3.42e-111 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HHIGLKPN_00414 3.08e-152 - - - - - - - -
HHIGLKPN_00415 6.89e-191 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HHIGLKPN_00416 1.69e-191 - - - S - - - hydrolase
HHIGLKPN_00417 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HHIGLKPN_00418 2.62e-218 ybbR - - S - - - YbbR-like protein
HHIGLKPN_00419 8.69e-194 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HHIGLKPN_00420 1.71e-266 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HHIGLKPN_00421 3.23e-180 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HHIGLKPN_00422 1.85e-174 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HHIGLKPN_00423 4.51e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HHIGLKPN_00424 1.71e-209 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HHIGLKPN_00425 7.47e-128 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HHIGLKPN_00426 1.87e-118 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
HHIGLKPN_00427 3.84e-233 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
HHIGLKPN_00428 2.33e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HHIGLKPN_00429 3.42e-202 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
HHIGLKPN_00430 1.46e-123 - - - - - - - -
HHIGLKPN_00431 6.64e-184 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HHIGLKPN_00432 6.01e-288 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HHIGLKPN_00433 1.65e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HHIGLKPN_00434 6.71e-241 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
HHIGLKPN_00436 1.73e-96 - - - - - - - -
HHIGLKPN_00437 1.87e-210 - - - - - - - -
HHIGLKPN_00438 0.0 ycaM - - E - - - amino acid
HHIGLKPN_00439 5.08e-170 supH - - S - - - haloacid dehalogenase-like hydrolase
HHIGLKPN_00440 0.0 - - - S - - - SH3-like domain
HHIGLKPN_00441 2.99e-127 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HHIGLKPN_00442 1.73e-116 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
HHIGLKPN_00443 8.58e-290 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HHIGLKPN_00444 4.12e-47 - - - - - - - -
HHIGLKPN_00445 2.02e-101 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
HHIGLKPN_00446 2.08e-84 - - - S - - - Cupredoxin-like domain
HHIGLKPN_00447 1.81e-64 - - - S - - - Cupredoxin-like domain
HHIGLKPN_00448 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HHIGLKPN_00449 8.26e-22 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
HHIGLKPN_00450 5.89e-48 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
HHIGLKPN_00451 4.61e-99 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
HHIGLKPN_00452 6.46e-27 - - - - - - - -
HHIGLKPN_00453 6.76e-269 - - - - - - - -
HHIGLKPN_00454 0.0 eriC - - P ko:K03281 - ko00000 chloride
HHIGLKPN_00455 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HHIGLKPN_00456 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HHIGLKPN_00457 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HHIGLKPN_00458 5.34e-189 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHIGLKPN_00459 1.31e-81 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HHIGLKPN_00460 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
HHIGLKPN_00461 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HHIGLKPN_00462 4.3e-256 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HHIGLKPN_00463 4.08e-47 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
HHIGLKPN_00464 2.09e-267 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HHIGLKPN_00465 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHIGLKPN_00466 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHIGLKPN_00467 1.93e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HHIGLKPN_00468 7.17e-110 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HHIGLKPN_00469 1.89e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HHIGLKPN_00470 4.36e-41 - - - S - - - SLAP domain
HHIGLKPN_00471 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HHIGLKPN_00472 7.8e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HHIGLKPN_00473 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HHIGLKPN_00474 4.01e-209 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
HHIGLKPN_00475 6.88e-223 degV1 - - S - - - DegV family
HHIGLKPN_00476 2.99e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HHIGLKPN_00477 5.02e-69 - - - L - - - An automated process has identified a potential problem with this gene model
HHIGLKPN_00478 1.26e-214 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HHIGLKPN_00479 2.38e-176 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
HHIGLKPN_00482 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
HHIGLKPN_00483 4.7e-35 - - - - - - - -
HHIGLKPN_00484 8.68e-44 - - - - - - - -
HHIGLKPN_00485 7.29e-46 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HHIGLKPN_00486 4.94e-49 - - - S - - - Enterocin A Immunity
HHIGLKPN_00487 1.05e-19 - - - S - - - Enterocin A Immunity
HHIGLKPN_00488 1.28e-267 - - - S ko:K06921 - ko00000 Archaea bacterial proteins of unknown function
HHIGLKPN_00489 3.86e-186 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HHIGLKPN_00490 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HHIGLKPN_00491 3.61e-267 - - - T - - - His Kinase A (phosphoacceptor) domain
HHIGLKPN_00492 2.9e-157 vanR - - K - - - response regulator
HHIGLKPN_00493 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
HHIGLKPN_00494 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
HHIGLKPN_00495 1.88e-178 - - - S - - - Protein of unknown function (DUF1129)
HHIGLKPN_00496 2.8e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HHIGLKPN_00497 1.83e-58 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
HHIGLKPN_00498 3.96e-197 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HHIGLKPN_00499 1.13e-174 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
HHIGLKPN_00500 3.14e-191 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HHIGLKPN_00501 9.37e-169 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HHIGLKPN_00502 2.12e-114 cvpA - - S - - - Colicin V production protein
HHIGLKPN_00503 3.16e-231 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HHIGLKPN_00504 2.14e-190 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HHIGLKPN_00505 1.82e-126 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
HHIGLKPN_00506 5.66e-124 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
HHIGLKPN_00507 4.79e-140 - - - K - - - WHG domain
HHIGLKPN_00508 4.74e-51 - - - - - - - -
HHIGLKPN_00509 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HHIGLKPN_00510 1.89e-151 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HHIGLKPN_00511 1.71e-225 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HHIGLKPN_00512 1.7e-123 - - - K - - - Bacterial regulatory proteins, tetR family
HHIGLKPN_00513 4.23e-145 - - - G - - - phosphoglycerate mutase
HHIGLKPN_00514 2.21e-177 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
HHIGLKPN_00515 2.06e-183 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HHIGLKPN_00516 1.35e-155 - - - - - - - -
HHIGLKPN_00517 3.84e-62 - - - C - - - Domain of unknown function (DUF4931)
HHIGLKPN_00518 1.17e-29 repA - - S - - - Replication initiator protein A
HHIGLKPN_00519 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HHIGLKPN_00520 2.12e-164 csrR - - K - - - response regulator
HHIGLKPN_00521 2.47e-125 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HHIGLKPN_00522 1.09e-273 ylbM - - S - - - Belongs to the UPF0348 family
HHIGLKPN_00523 3.58e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HHIGLKPN_00524 9.6e-143 yqeK - - H - - - Hydrolase, HD family
HHIGLKPN_00525 4.51e-156 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HHIGLKPN_00526 1.94e-269 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
HHIGLKPN_00527 1.51e-121 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
HHIGLKPN_00528 1.23e-75 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HHIGLKPN_00529 2.77e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HHIGLKPN_00530 4.65e-71 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HHIGLKPN_00531 2.51e-43 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
HHIGLKPN_00532 6.71e-197 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
HHIGLKPN_00533 2.61e-36 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
HHIGLKPN_00534 3.9e-247 - - - S - - - Domain of unknown function (DUF389)
HHIGLKPN_00535 1.51e-122 - - - - - - - -
HHIGLKPN_00536 4.51e-118 - - - - - - - -
HHIGLKPN_00537 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HHIGLKPN_00538 8.5e-212 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HHIGLKPN_00539 1.76e-314 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
HHIGLKPN_00540 5.46e-108 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HHIGLKPN_00541 1.03e-134 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HHIGLKPN_00542 1.77e-200 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HHIGLKPN_00543 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HHIGLKPN_00544 2.56e-19 - - - - - - - -
HHIGLKPN_00545 2.86e-39 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HHIGLKPN_00546 3.52e-252 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HHIGLKPN_00547 1.4e-159 cas4 3.1.12.1 - L ko:K07464 - ko00000,ko01000,ko02048 Domain of unknown function DUF83
HHIGLKPN_00548 3.18e-202 csd2 - - L ko:K19115,ko:K19118 - ko00000,ko02048 CRISPR-associated protein Cas7
HHIGLKPN_00549 0.0 csd1 - - M ko:K19117 - ko00000,ko02048 CRISPR-associated protein (Cas_Csd1)
HHIGLKPN_00550 1.24e-181 cas5 - - S ko:K19119 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas5)
HHIGLKPN_00551 0.0 - - - L ko:K07012 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
HHIGLKPN_00552 6.34e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HHIGLKPN_00553 3.29e-146 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HHIGLKPN_00554 5.47e-137 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HHIGLKPN_00555 4.67e-63 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HHIGLKPN_00556 1.63e-197 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HHIGLKPN_00557 1.24e-61 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HHIGLKPN_00558 9.07e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HHIGLKPN_00559 1.75e-156 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HHIGLKPN_00560 1.66e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HHIGLKPN_00561 1.45e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HHIGLKPN_00562 1.56e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HHIGLKPN_00563 2.1e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HHIGLKPN_00564 1.64e-43 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HHIGLKPN_00565 7.13e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HHIGLKPN_00566 1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HHIGLKPN_00567 2.28e-89 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HHIGLKPN_00568 5.05e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HHIGLKPN_00569 3.67e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HHIGLKPN_00570 2.63e-110 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HHIGLKPN_00571 2.22e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HHIGLKPN_00572 1.73e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HHIGLKPN_00573 5.1e-301 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HHIGLKPN_00574 2.61e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HHIGLKPN_00575 3.13e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HHIGLKPN_00576 1.89e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HHIGLKPN_00577 1.46e-73 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HHIGLKPN_00578 3.82e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HHIGLKPN_00579 3.62e-218 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHIGLKPN_00580 1.83e-79 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HHIGLKPN_00581 2.69e-195 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHIGLKPN_00582 3.56e-191 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHIGLKPN_00583 5.22e-179 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHIGLKPN_00584 1.23e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HHIGLKPN_00585 6.51e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HHIGLKPN_00586 5.83e-87 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HHIGLKPN_00587 2.17e-61 yhaH - - S - - - Protein of unknown function (DUF805)
HHIGLKPN_00588 1.17e-137 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
HHIGLKPN_00589 6.56e-145 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HHIGLKPN_00590 2.57e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
HHIGLKPN_00591 1.9e-161 - - - G - - - Belongs to the phosphoglycerate mutase family
HHIGLKPN_00592 5.3e-209 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
HHIGLKPN_00593 4.73e-31 - - - - - - - -
HHIGLKPN_00594 3.29e-162 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HHIGLKPN_00595 3.29e-234 - - - S - - - AAA domain
HHIGLKPN_00596 2.86e-132 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HHIGLKPN_00597 8.97e-144 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HHIGLKPN_00598 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
HHIGLKPN_00599 6.47e-14 - - - - - - - -
HHIGLKPN_00600 4.42e-187 - - - U ko:K05340 - ko00000,ko02000 sugar transport
HHIGLKPN_00601 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HHIGLKPN_00605 1.95e-272 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HHIGLKPN_00606 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HHIGLKPN_00607 2.79e-115 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HHIGLKPN_00608 1.02e-238 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HHIGLKPN_00609 3.03e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HHIGLKPN_00610 2.35e-211 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HHIGLKPN_00611 6.79e-79 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HHIGLKPN_00612 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HHIGLKPN_00613 2.2e-62 ylxQ - - J - - - ribosomal protein
HHIGLKPN_00614 9.2e-64 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
HHIGLKPN_00615 2.72e-263 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HHIGLKPN_00616 4.83e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HHIGLKPN_00617 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHIGLKPN_00618 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HHIGLKPN_00619 1.83e-253 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HHIGLKPN_00620 1.62e-189 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HHIGLKPN_00621 3.04e-176 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HHIGLKPN_00622 8.57e-122 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HHIGLKPN_00623 2.38e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HHIGLKPN_00624 4.33e-236 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HHIGLKPN_00625 1.56e-180 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HHIGLKPN_00626 1.82e-254 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
HHIGLKPN_00627 1.46e-145 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
HHIGLKPN_00628 9.19e-287 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HHIGLKPN_00629 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HHIGLKPN_00630 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HHIGLKPN_00631 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HHIGLKPN_00632 6.43e-41 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
HHIGLKPN_00633 5.3e-49 ynzC - - S - - - UPF0291 protein
HHIGLKPN_00634 1.99e-145 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HHIGLKPN_00635 3.17e-191 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HHIGLKPN_00636 2.31e-154 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
HHIGLKPN_00637 2.28e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HHIGLKPN_00638 2.41e-175 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HHIGLKPN_00639 1.41e-120 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HHIGLKPN_00640 5.58e-59 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HHIGLKPN_00641 3.29e-290 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HHIGLKPN_00642 1.17e-73 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HHIGLKPN_00643 5.8e-247 - - - L - - - Transposase and inactivated derivatives, IS30 family
HHIGLKPN_00644 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
HHIGLKPN_00645 3.87e-60 - - - - - - - -
HHIGLKPN_00646 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HHIGLKPN_00647 1.04e-221 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HHIGLKPN_00648 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HHIGLKPN_00649 1.56e-161 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HHIGLKPN_00650 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HHIGLKPN_00651 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HHIGLKPN_00652 5.59e-200 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHIGLKPN_00653 2.12e-225 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HHIGLKPN_00654 3.41e-231 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HHIGLKPN_00655 1.17e-246 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HHIGLKPN_00656 1.79e-46 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHIGLKPN_00657 1.57e-234 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HHIGLKPN_00658 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HHIGLKPN_00659 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
HHIGLKPN_00660 1.67e-74 yloU - - S - - - Asp23 family, cell envelope-related function
HHIGLKPN_00661 3.82e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HHIGLKPN_00662 4.85e-65 - - - - - - - -
HHIGLKPN_00663 4.3e-159 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HHIGLKPN_00664 4.86e-150 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HHIGLKPN_00665 6.49e-213 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HHIGLKPN_00666 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HHIGLKPN_00667 3.85e-188 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HHIGLKPN_00668 2.87e-311 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HHIGLKPN_00669 5.58e-221 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HHIGLKPN_00670 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HHIGLKPN_00671 5.6e-45 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HHIGLKPN_00672 6.69e-142 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HHIGLKPN_00673 1.73e-102 - - - S - - - ASCH
HHIGLKPN_00674 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HHIGLKPN_00675 8.09e-194 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HHIGLKPN_00676 1.45e-201 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HHIGLKPN_00677 4.4e-47 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHIGLKPN_00678 5.59e-251 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHIGLKPN_00679 1.83e-196 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HHIGLKPN_00680 5.2e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HHIGLKPN_00681 1.89e-90 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
HHIGLKPN_00682 1e-131 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HHIGLKPN_00683 1.64e-261 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HHIGLKPN_00684 5.95e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HHIGLKPN_00685 6.82e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HHIGLKPN_00686 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
HHIGLKPN_00687 4.64e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HHIGLKPN_00688 2.32e-166 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HHIGLKPN_00689 4.18e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
HHIGLKPN_00690 0.0 - - - S - - - Predicted membrane protein (DUF2207)
HHIGLKPN_00691 1.15e-267 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HHIGLKPN_00693 1.15e-142 ackA 2.7.2.1 - H ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHIGLKPN_00694 5.61e-224 yvdE - - K - - - helix_turn _helix lactose operon repressor
HHIGLKPN_00695 1.91e-190 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HHIGLKPN_00696 3e-289 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HHIGLKPN_00697 4.88e-195 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HHIGLKPN_00699 1.29e-169 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
HHIGLKPN_00700 1.38e-108 - - - M - - - NlpC/P60 family
HHIGLKPN_00701 1.57e-189 - - - EG - - - EamA-like transporter family
HHIGLKPN_00702 8.31e-141 - - - - - - - -
HHIGLKPN_00703 2.61e-101 - - - - - - - -
HHIGLKPN_00704 1.69e-234 - - - S - - - DUF218 domain
HHIGLKPN_00705 1.15e-170 yheS_2 - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
HHIGLKPN_00706 5.86e-39 yheS_2 - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
HHIGLKPN_00707 7.7e-110 - - - - - - - -
HHIGLKPN_00708 2.89e-75 - - - - - - - -
HHIGLKPN_00709 5.62e-310 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HHIGLKPN_00710 1.14e-312 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HHIGLKPN_00711 2.73e-232 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HHIGLKPN_00714 1.83e-258 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
HHIGLKPN_00715 2.64e-244 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
HHIGLKPN_00716 2.21e-61 - - - E - - - amino acid
HHIGLKPN_00717 7.6e-223 - - - E - - - amino acid
HHIGLKPN_00718 2.24e-176 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HHIGLKPN_00719 4.14e-311 yifK - - E ko:K03293 - ko00000 Amino acid permease
HHIGLKPN_00720 2.19e-300 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HHIGLKPN_00721 2.95e-163 - - - - - - - -
HHIGLKPN_00722 3.58e-155 sipS3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HHIGLKPN_00723 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 AAA domain (Cdc48 subfamily)
HHIGLKPN_00724 7.98e-200 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HHIGLKPN_00725 3.37e-274 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHIGLKPN_00726 8.84e-305 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HHIGLKPN_00727 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HHIGLKPN_00728 1.03e-133 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HHIGLKPN_00729 1.26e-246 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HHIGLKPN_00730 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HHIGLKPN_00731 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHIGLKPN_00732 1.56e-154 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHIGLKPN_00733 1.27e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHIGLKPN_00734 1.19e-170 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HHIGLKPN_00735 2.69e-276 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HHIGLKPN_00736 1.87e-102 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HHIGLKPN_00737 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HHIGLKPN_00738 3.72e-159 - - - C - - - Flavodoxin
HHIGLKPN_00739 9.65e-193 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
HHIGLKPN_00740 1.87e-68 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
HHIGLKPN_00741 1.74e-28 - - - - - - - -
HHIGLKPN_00742 4.58e-248 - - - S - - - Bacteriocin helveticin-J
HHIGLKPN_00743 1.05e-47 - - - M - - - Peptidase family M1 domain
HHIGLKPN_00744 2.69e-178 - - - M - - - Peptidase family M1 domain
HHIGLKPN_00745 2.61e-76 - - - M - - - Peptidase family M1 domain
HHIGLKPN_00746 2.38e-225 - - - S - - - SLAP domain
HHIGLKPN_00747 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HHIGLKPN_00748 0.0 - - - S - - - SLAP domain
HHIGLKPN_00749 3.06e-157 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHIGLKPN_00750 1.64e-72 ytpP - - CO - - - Thioredoxin
HHIGLKPN_00751 7.82e-161 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HHIGLKPN_00752 1.26e-269 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HHIGLKPN_00753 9.02e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HHIGLKPN_00754 6.86e-72 - - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
HHIGLKPN_00755 2.77e-103 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
HHIGLKPN_00756 6.03e-57 - - - - - - - -
HHIGLKPN_00757 2.68e-198 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HHIGLKPN_00758 2.13e-186 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
HHIGLKPN_00759 1.58e-301 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
HHIGLKPN_00760 4.69e-301 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HHIGLKPN_00761 1.51e-104 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
HHIGLKPN_00762 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
HHIGLKPN_00763 8.76e-73 yitW - - S - - - Iron-sulfur cluster assembly protein
HHIGLKPN_00764 4.25e-82 - - - S - - - Enterocin A Immunity
HHIGLKPN_00765 2.87e-170 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
HHIGLKPN_00766 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HHIGLKPN_00767 3.74e-205 - - - S - - - Phospholipase, patatin family
HHIGLKPN_00768 2.65e-18 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HHIGLKPN_00769 1.83e-109 - - - S - - - hydrolase
HHIGLKPN_00770 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HHIGLKPN_00771 5.32e-176 glvR - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
HHIGLKPN_00772 1.5e-94 - - - - - - - -
HHIGLKPN_00773 6.56e-112 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HHIGLKPN_00774 1.43e-52 - - - - - - - -
HHIGLKPN_00775 3.42e-19 - - - C - - - nitroreductase
HHIGLKPN_00776 1.31e-39 - - - C - - - nitroreductase
HHIGLKPN_00777 2.23e-313 yhdP - - S - - - Transporter associated domain
HHIGLKPN_00778 1.73e-132 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HHIGLKPN_00779 5.61e-272 - - - E ko:K03294 - ko00000 amino acid
HHIGLKPN_00780 4.29e-162 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HHIGLKPN_00781 6.71e-268 yfmL - - L - - - DEAD DEAH box helicase
HHIGLKPN_00782 6.64e-314 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHIGLKPN_00784 5.82e-35 - - - - - - - -
HHIGLKPN_00785 3.82e-277 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HHIGLKPN_00786 5.57e-114 gtcA1 - - S - - - Teichoic acid glycosylation protein
HHIGLKPN_00787 3.48e-103 ykuP - - C ko:K03839 - ko00000 Flavodoxin
HHIGLKPN_00788 9.98e-211 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
HHIGLKPN_00789 3.23e-198 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HHIGLKPN_00790 1.65e-212 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HHIGLKPN_00791 4.4e-288 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HHIGLKPN_00792 8.42e-204 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HHIGLKPN_00793 3.68e-295 XK27_05225 - - S - - - Tetratricopeptide repeat protein
HHIGLKPN_00794 1.17e-56 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HHIGLKPN_00795 1.82e-312 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HHIGLKPN_00796 6.32e-274 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HHIGLKPN_00797 2.57e-149 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HHIGLKPN_00798 3.4e-56 - - - M - - - Lysin motif
HHIGLKPN_00799 1.31e-149 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HHIGLKPN_00800 3.66e-165 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HHIGLKPN_00801 1.16e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HHIGLKPN_00802 1.22e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HHIGLKPN_00803 1.62e-80 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHIGLKPN_00804 1.73e-215 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
HHIGLKPN_00805 7.31e-215 yitL - - S ko:K00243 - ko00000 S1 domain
HHIGLKPN_00806 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HHIGLKPN_00807 6.65e-234 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HHIGLKPN_00808 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HHIGLKPN_00809 9.47e-43 - - - S - - - Protein of unknown function (DUF2929)
HHIGLKPN_00810 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HHIGLKPN_00811 3.62e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HHIGLKPN_00812 6.62e-48 - - - S - - - Lipopolysaccharide assembly protein A domain
HHIGLKPN_00813 7.14e-185 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HHIGLKPN_00814 7.11e-225 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HHIGLKPN_00815 0.0 oatA - - I - - - Acyltransferase
HHIGLKPN_00816 1.55e-308 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HHIGLKPN_00817 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HHIGLKPN_00818 3.23e-38 repA - - S - - - Replication initiator protein A
HHIGLKPN_00819 9.39e-184 - - - D - - - AAA domain
HHIGLKPN_00820 4.07e-39 - - - - - - - -
HHIGLKPN_00821 3.51e-24 - - - NU - - - Mycoplasma protein of unknown function, DUF285
HHIGLKPN_00822 1.64e-147 - - - S - - - Domain of unknown function (DUF4430)
HHIGLKPN_00823 9.08e-237 - - - U - - - FFAT motif binding
HHIGLKPN_00824 0.0 - - - S ko:K21449 - ko00000,ko02000 Domain of unknown function (DUF4430)
HHIGLKPN_00825 8e-199 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type cobalt transport system permease component CbiQ and related transporters
HHIGLKPN_00826 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HHIGLKPN_00827 1.23e-162 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF-type riboflavin transporter, S component
HHIGLKPN_00828 2.37e-28 - - - EGP - - - Major Facilitator Superfamily
HHIGLKPN_00830 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
HHIGLKPN_00831 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
HHIGLKPN_00832 4.26e-137 - - - V - - - Type I restriction
HHIGLKPN_00833 5.78e-32 - - - - - - - -
HHIGLKPN_00834 5.58e-251 - - - L - - - Psort location Cytoplasmic, score
HHIGLKPN_00835 3.73e-44 - - - - - - - -
HHIGLKPN_00836 0.0 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HHIGLKPN_00837 0.0 - - - L - - - MobA MobL family protein
HHIGLKPN_00838 3.99e-36 - - - - - - - -
HHIGLKPN_00839 8.5e-55 - - - - - - - -
HHIGLKPN_00840 7.7e-22 - - - S - - - zinc-ribbon domain
HHIGLKPN_00841 5.76e-54 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
HHIGLKPN_00842 9.04e-87 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
HHIGLKPN_00843 6.83e-84 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
HHIGLKPN_00844 2.75e-09 - - - - - - - -
HHIGLKPN_00845 1.95e-108 tdh 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
HHIGLKPN_00846 2.62e-104 tdh 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
HHIGLKPN_00847 1.48e-25 - - - - - - - -
HHIGLKPN_00848 1.4e-35 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HHIGLKPN_00849 5.59e-303 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HHIGLKPN_00850 5.97e-56 mleR2 - - K - - - LysR substrate binding domain
HHIGLKPN_00851 2.43e-18 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HHIGLKPN_00852 1.33e-88 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HHIGLKPN_00853 3.05e-307 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HHIGLKPN_00854 2.03e-73 - - - - - - - -
HHIGLKPN_00855 4.15e-48 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HHIGLKPN_00856 2.82e-152 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HHIGLKPN_00857 8.9e-51 - - - - - - - -
HHIGLKPN_00858 5.43e-133 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
HHIGLKPN_00859 4.86e-120 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HHIGLKPN_00860 0.0 - - - S - - - C4-dicarboxylate anaerobic carrier
HHIGLKPN_00861 8.08e-262 - - - - - - - -
HHIGLKPN_00862 8.49e-108 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
HHIGLKPN_00863 1.58e-33 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
HHIGLKPN_00864 6.52e-308 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HHIGLKPN_00865 3.35e-40 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HHIGLKPN_00866 7.11e-20 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HHIGLKPN_00867 1.3e-72 steT - - E ko:K03294 - ko00000 amino acid
HHIGLKPN_00868 2.77e-78 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
HHIGLKPN_00869 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HHIGLKPN_00870 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HHIGLKPN_00872 9.99e-40 cspA - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HHIGLKPN_00873 0.0 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
HHIGLKPN_00874 2.56e-220 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HHIGLKPN_00875 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHIGLKPN_00876 7.74e-312 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HHIGLKPN_00877 9.6e-73 - - - - - - - -
HHIGLKPN_00878 2.1e-153 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HHIGLKPN_00879 5.53e-147 ybbB - - S - - - Protein of unknown function (DUF1211)
HHIGLKPN_00880 2.65e-217 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
HHIGLKPN_00881 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHIGLKPN_00882 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HHIGLKPN_00883 2.94e-66 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHIGLKPN_00884 5.99e-266 camS - - S - - - sex pheromone
HHIGLKPN_00885 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HHIGLKPN_00886 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HHIGLKPN_00887 3.4e-145 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
HHIGLKPN_00889 1.1e-112 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HHIGLKPN_00890 4.89e-176 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
HHIGLKPN_00891 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HHIGLKPN_00892 8.61e-286 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HHIGLKPN_00893 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HHIGLKPN_00894 5.7e-68 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HHIGLKPN_00895 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
HHIGLKPN_00896 1.27e-313 ynbB - - P - - - aluminum resistance
HHIGLKPN_00897 1.15e-98 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
HHIGLKPN_00898 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HHIGLKPN_00899 1.79e-101 - - - C - - - Flavodoxin
HHIGLKPN_00900 6.65e-145 - - - I - - - Acid phosphatase homologues
HHIGLKPN_00901 1.46e-145 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HHIGLKPN_00902 3.74e-265 - - - V - - - Beta-lactamase
HHIGLKPN_00903 9.09e-193 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
HHIGLKPN_00904 8.22e-120 - - - S - - - ECF-type riboflavin transporter, S component
HHIGLKPN_00905 1.43e-294 - - - S - - - Putative peptidoglycan binding domain
HHIGLKPN_00906 1.21e-301 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
HHIGLKPN_00907 0.0 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HHIGLKPN_00908 9.66e-46 - - - - - - - -
HHIGLKPN_00909 6.11e-40 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
HHIGLKPN_00910 2.32e-79 - - - - - - - -
HHIGLKPN_00911 0.0 - - - P ko:K06148 - ko00000,ko02000 ABC transporter
HHIGLKPN_00912 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
HHIGLKPN_00913 1.18e-126 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
HHIGLKPN_00914 3.06e-77 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
HHIGLKPN_00916 5.1e-102 - - - - - - - -
HHIGLKPN_00917 8.78e-88 - - - - - - - -
HHIGLKPN_00918 5.12e-151 - - - S - - - Fic/DOC family
HHIGLKPN_00919 3.34e-132 - - - - - - - -
HHIGLKPN_00920 4.04e-265 - - - EGP - - - Major Facilitator Superfamily
HHIGLKPN_00921 1.29e-173 - - - - - - - -
HHIGLKPN_00922 9.66e-110 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
HHIGLKPN_00923 7.05e-204 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHIGLKPN_00924 3.93e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HHIGLKPN_00925 1.18e-174 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHIGLKPN_00926 1.4e-80 yodB - - K - - - Transcriptional regulator, HxlR family
HHIGLKPN_00927 9.05e-258 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HHIGLKPN_00928 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHIGLKPN_00929 2.25e-88 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HHIGLKPN_00930 1.79e-214 ldh3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
HHIGLKPN_00931 5.22e-36 - - - S - - - Phage derived protein Gp49-like (DUF891)
HHIGLKPN_00932 1.67e-51 - - - K - - - Helix-turn-helix domain
HHIGLKPN_00933 5.79e-217 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
HHIGLKPN_00934 0.0 - - - S - - - membrane
HHIGLKPN_00935 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HHIGLKPN_00936 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HHIGLKPN_00937 3.12e-129 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HHIGLKPN_00938 4.44e-151 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
HHIGLKPN_00939 2.45e-44 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
HHIGLKPN_00940 3.1e-92 yqhL - - P - - - Rhodanese-like protein
HHIGLKPN_00941 9.65e-220 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HHIGLKPN_00942 2.78e-37 ynbB - - P - - - aluminum resistance
HHIGLKPN_00943 1.45e-212 ynbB - - P - - - aluminum resistance
HHIGLKPN_00944 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HHIGLKPN_00945 8.93e-173 - - - - - - - -
HHIGLKPN_00946 1.59e-211 - - - - - - - -
HHIGLKPN_00947 6.91e-203 - - - - - - - -
HHIGLKPN_00948 1.29e-21 - - - - - - - -
HHIGLKPN_00949 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HHIGLKPN_00950 9.65e-152 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
HHIGLKPN_00951 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HHIGLKPN_00952 1.99e-122 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HHIGLKPN_00953 4.56e-215 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HHIGLKPN_00954 1.52e-195 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
HHIGLKPN_00955 3.5e-137 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHIGLKPN_00956 1.96e-128 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHIGLKPN_00957 3.75e-109 - 3.4.21.96 - S ko:K01361 - ko00000,ko01000,ko01002,ko03110 SLAP domain
HHIGLKPN_00958 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
HHIGLKPN_00959 1.71e-202 lysR5 - - K - - - LysR substrate binding domain
HHIGLKPN_00960 5.18e-28 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
HHIGLKPN_00961 6.65e-19 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
HHIGLKPN_00962 6.12e-114 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
HHIGLKPN_00963 7.7e-17 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HHIGLKPN_00964 5.91e-184 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HHIGLKPN_00965 1.23e-87 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
HHIGLKPN_00966 1.33e-66 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
HHIGLKPN_00967 7.45e-124 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HHIGLKPN_00968 3.04e-278 - - - S - - - Sterol carrier protein domain
HHIGLKPN_00969 5.55e-27 - - - - - - - -
HHIGLKPN_00970 5.72e-137 - - - K - - - LysR substrate binding domain
HHIGLKPN_00971 2.71e-98 - - - - - - - -
HHIGLKPN_00973 7.84e-195 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HHIGLKPN_00974 4.16e-151 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
HHIGLKPN_00975 5.73e-117 - - - S - - - Protein of unknown function (DUF1461)
HHIGLKPN_00976 1.24e-187 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HHIGLKPN_00977 3.11e-128 yutD - - S - - - Protein of unknown function (DUF1027)
HHIGLKPN_00978 0.0 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HHIGLKPN_00979 2.42e-74 - - - - - - - -
HHIGLKPN_00980 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HHIGLKPN_00981 6.84e-229 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HHIGLKPN_00982 9.67e-274 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HHIGLKPN_00983 3.09e-69 - - - - - - - -
HHIGLKPN_00984 3.11e-28 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HHIGLKPN_00985 4.28e-191 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
HHIGLKPN_00986 2.16e-148 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HHIGLKPN_00987 3.98e-188 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HHIGLKPN_00988 3.63e-91 yslB - - S - - - Protein of unknown function (DUF2507)
HHIGLKPN_00989 3.3e-64 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HHIGLKPN_00990 5.37e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HHIGLKPN_00991 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HHIGLKPN_00992 4.8e-66 yrzB - - S - - - Belongs to the UPF0473 family
HHIGLKPN_00993 2.69e-95 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HHIGLKPN_00994 5.32e-57 yrzL - - S - - - Belongs to the UPF0297 family
HHIGLKPN_00995 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HHIGLKPN_00996 2.67e-111 - - - - - - - -
HHIGLKPN_00997 4.66e-83 - - - - - - - -
HHIGLKPN_00998 5.24e-312 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HHIGLKPN_00999 1.56e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
HHIGLKPN_01000 9.26e-270 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHIGLKPN_01001 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HHIGLKPN_01002 1.42e-76 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HHIGLKPN_01003 4.17e-237 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HHIGLKPN_01004 1.47e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HHIGLKPN_01005 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HHIGLKPN_01006 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HHIGLKPN_01007 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HHIGLKPN_01008 9.06e-60 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HHIGLKPN_01009 9.71e-116 - - - - - - - -
HHIGLKPN_01010 7.04e-63 - - - - - - - -
HHIGLKPN_01011 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HHIGLKPN_01012 1.14e-290 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HHIGLKPN_01013 1.39e-230 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
HHIGLKPN_01014 1.26e-161 - - - S - - - membrane
HHIGLKPN_01015 4.34e-101 - - - K - - - LytTr DNA-binding domain
HHIGLKPN_01016 3.4e-150 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HHIGLKPN_01017 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
HHIGLKPN_01018 2.43e-17 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HHIGLKPN_01019 5.37e-274 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HHIGLKPN_01020 3.89e-46 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HHIGLKPN_01021 9.31e-142 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HHIGLKPN_01022 1.97e-136 bbsF_1 2.8.3.19 - C ko:K18702 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HHIGLKPN_01023 1.35e-140 bbsF_1 2.8.3.19 - C ko:K18702 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HHIGLKPN_01024 5.42e-12 - - - S - - - Toxin ToxN, type III toxin-antitoxin system
HHIGLKPN_01025 9.39e-167 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
HHIGLKPN_01026 3.42e-233 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HHIGLKPN_01027 4.97e-160 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HHIGLKPN_01028 2.16e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HHIGLKPN_01029 4.59e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
HHIGLKPN_01030 2.22e-168 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
HHIGLKPN_01031 9.09e-113 - - - S - - - ECF transporter, substrate-specific component
HHIGLKPN_01032 3.43e-182 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HHIGLKPN_01033 1.29e-197 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HHIGLKPN_01034 1.35e-78 yabA - - L - - - Involved in initiation control of chromosome replication
HHIGLKPN_01035 1.39e-197 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HHIGLKPN_01036 6.21e-68 yaaQ - - S - - - Cyclic-di-AMP receptor
HHIGLKPN_01037 8.42e-149 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HHIGLKPN_01038 5.61e-45 - - - S - - - Protein of unknown function (DUF2508)
HHIGLKPN_01039 5.33e-141 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HHIGLKPN_01040 6.03e-57 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HHIGLKPN_01041 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHIGLKPN_01042 9.21e-120 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HHIGLKPN_01043 5.5e-148 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HHIGLKPN_01044 3.75e-102 - 2.1.1.172 - J ko:K00564,ko:K10716 - ko00000,ko01000,ko02000,ko03009 Ion channel
HHIGLKPN_01045 2.67e-71 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HHIGLKPN_01046 1.77e-109 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HHIGLKPN_01047 3.89e-197 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
HHIGLKPN_01048 3.34e-13 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
HHIGLKPN_01049 1.43e-151 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HHIGLKPN_01050 2.31e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHIGLKPN_01051 2.49e-185 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHIGLKPN_01052 7.41e-198 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
HHIGLKPN_01053 4.05e-220 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HHIGLKPN_01054 4.5e-200 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HHIGLKPN_01055 3.02e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HHIGLKPN_01056 3.82e-90 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HHIGLKPN_01057 8.63e-131 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HHIGLKPN_01058 1.21e-33 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HHIGLKPN_01059 3.27e-225 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HHIGLKPN_01060 1.58e-140 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HHIGLKPN_01061 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HHIGLKPN_01062 1.4e-44 - - - - - - - -
HHIGLKPN_01063 4.27e-120 comX - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
HHIGLKPN_01064 1.76e-178 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHIGLKPN_01065 2.1e-99 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HHIGLKPN_01066 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HHIGLKPN_01067 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HHIGLKPN_01068 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HHIGLKPN_01069 1.56e-132 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
HHIGLKPN_01070 5.04e-71 - - - - - - - -
HHIGLKPN_01071 3.27e-168 - - - S - - - Phage Mu protein F like protein
HHIGLKPN_01072 3.62e-22 ytgB - - S - - - Transglycosylase associated protein
HHIGLKPN_01073 9.93e-160 tnp1216 - - L ko:K07498 - ko00000 DDE domain
HHIGLKPN_01074 2.25e-72 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HHIGLKPN_01075 2.84e-158 - - - L - - - Transposase DDE domain
HHIGLKPN_01078 2.08e-202 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HHIGLKPN_01079 2.71e-211 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
HHIGLKPN_01080 2.53e-204 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
HHIGLKPN_01081 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HHIGLKPN_01082 7.73e-256 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
HHIGLKPN_01083 3.85e-201 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
HHIGLKPN_01084 5.62e-187 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHIGLKPN_01085 0.0 - - - S - - - Zn-dependent metallo-hydrolase RNA specificity domain
HHIGLKPN_01086 1.17e-307 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHIGLKPN_01087 1.36e-214 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HHIGLKPN_01088 1.14e-207 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HHIGLKPN_01089 5.77e-127 yobS - - K - - - Bacterial regulatory proteins, tetR family
HHIGLKPN_01090 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
HHIGLKPN_01091 8.23e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HHIGLKPN_01092 1.27e-247 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HHIGLKPN_01093 2.09e-211 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HHIGLKPN_01094 2.64e-109 - - - S - - - Short repeat of unknown function (DUF308)
HHIGLKPN_01095 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HHIGLKPN_01096 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HHIGLKPN_01097 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HHIGLKPN_01098 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HHIGLKPN_01099 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HHIGLKPN_01100 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
HHIGLKPN_01101 1.82e-276 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
HHIGLKPN_01102 1.36e-266 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HHIGLKPN_01103 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HHIGLKPN_01104 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HHIGLKPN_01105 4.52e-140 vanZ - - V - - - VanZ like family
HHIGLKPN_01106 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HHIGLKPN_01107 0.0 yclK - - T - - - Histidine kinase
HHIGLKPN_01108 4.46e-167 - - - K - - - Transcriptional regulatory protein, C terminal
HHIGLKPN_01109 8.14e-80 - - - S - - - SdpI/YhfL protein family
HHIGLKPN_01110 3.23e-221 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HHIGLKPN_01111 4.03e-286 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HHIGLKPN_01112 5.04e-48 - - - M - - - Protein of unknown function (DUF3737)
HHIGLKPN_01113 1.38e-51 - - - M - - - Protein of unknown function (DUF3737)
HHIGLKPN_01115 3.19e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHIGLKPN_01116 2.95e-239 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HHIGLKPN_01117 5.97e-106 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
HHIGLKPN_01118 1.18e-55 - - - - - - - -
HHIGLKPN_01119 2.04e-95 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
HHIGLKPN_01120 6.15e-66 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
HHIGLKPN_01121 6.49e-223 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
HHIGLKPN_01122 1.33e-226 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
HHIGLKPN_01123 3.98e-171 yebC - - K - - - Transcriptional regulatory protein
HHIGLKPN_01124 5.73e-120 - - - S - - - VanZ like family
HHIGLKPN_01125 1.29e-257 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
HHIGLKPN_01126 1.65e-244 - - - S - - - SLAP domain
HHIGLKPN_01127 1.81e-224 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHIGLKPN_01128 7.09e-189 - - - GK - - - ROK family
HHIGLKPN_01129 5.78e-57 - - - - - - - -
HHIGLKPN_01130 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HHIGLKPN_01131 6.77e-87 - - - S - - - Domain of unknown function (DUF1934)
HHIGLKPN_01132 5.46e-95 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HHIGLKPN_01133 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HHIGLKPN_01134 8.98e-311 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HHIGLKPN_01135 9.13e-43 - - - S - - - Haloacid dehalogenase-like hydrolase
HHIGLKPN_01136 2.1e-63 - - - S - - - Haloacid dehalogenase-like hydrolase
HHIGLKPN_01137 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HHIGLKPN_01138 1.93e-203 msmR - - K - - - AraC-like ligand binding domain
HHIGLKPN_01139 5.72e-284 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
HHIGLKPN_01140 2.34e-127 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HHIGLKPN_01141 2.38e-143 - - - K - - - DNA-binding helix-turn-helix protein
HHIGLKPN_01142 1.73e-24 - - - K - - - Helix-turn-helix
HHIGLKPN_01143 5.15e-24 - - - K - - - Helix-turn-helix
HHIGLKPN_01144 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HHIGLKPN_01145 4.58e-84 - - - S - - - Domain of unknown function (DUF4411)
HHIGLKPN_01146 4.64e-108 - - - U ko:K05340 - ko00000,ko02000 sugar transport
HHIGLKPN_01147 4.89e-54 - - - U ko:K05340 - ko00000,ko02000 sugar transport
HHIGLKPN_01148 1.29e-63 - - - - - - - -
HHIGLKPN_01149 4.44e-104 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HHIGLKPN_01150 5.21e-62 - - - - - - - -
HHIGLKPN_01151 5.11e-106 - - - K - - - Acetyltransferase (GNAT) domain
HHIGLKPN_01152 1.7e-189 - - - S - - - Protein of unknown function (DUF2785)
HHIGLKPN_01153 9.76e-36 - - - S - - - MazG-like family
HHIGLKPN_01154 1.32e-74 - - - - - - - -
HHIGLKPN_01155 7.55e-58 - - - - ko:K07473 - ko00000,ko02048 -
HHIGLKPN_01156 1.78e-42 - - - S - - - Protein of unknown function (DUF3923)
HHIGLKPN_01157 1.23e-67 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
HHIGLKPN_01158 1.49e-173 yxaM - - EGP - - - Major facilitator Superfamily
HHIGLKPN_01159 8.78e-30 codA - - F - - - Cytidine and deoxycytidylate deaminase zinc-binding region
HHIGLKPN_01160 7.6e-31 cdd 2.4.2.4, 3.5.4.5 - F ko:K00758,ko:K01489 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 ko00000,ko00001,ko01000 cytidine deaminase activity
HHIGLKPN_01161 2.64e-119 - - - S - - - AAA domain
HHIGLKPN_01162 2.92e-192 - - - M - - - Phosphotransferase enzyme family
HHIGLKPN_01163 2.14e-185 - - - F - - - Phosphorylase superfamily
HHIGLKPN_01164 5.9e-183 - - - F - - - Phosphorylase superfamily
HHIGLKPN_01165 9.88e-152 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
HHIGLKPN_01166 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HHIGLKPN_01167 1.36e-78 - - - S - - - Bacterial PH domain
HHIGLKPN_01168 7.87e-37 - - - - - - - -
HHIGLKPN_01169 6.33e-87 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
HHIGLKPN_01170 3.02e-228 lipA - - I - - - Carboxylesterase family
HHIGLKPN_01171 1.16e-106 - 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
HHIGLKPN_01173 2.21e-08 - - - S - - - Protein of unknown function (DUF3923)
HHIGLKPN_01174 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
HHIGLKPN_01175 5.75e-124 - - - K - - - Acetyltransferase (GNAT) domain
HHIGLKPN_01176 3e-48 - - - K - - - helix_turn_helix, mercury resistance
HHIGLKPN_01177 7.31e-81 - - - K - - - helix_turn_helix, mercury resistance
HHIGLKPN_01179 7.56e-77 - - - S - - - YjbR
HHIGLKPN_01180 2.15e-113 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
HHIGLKPN_01181 3.92e-141 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HHIGLKPN_01182 1.17e-114 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HHIGLKPN_01183 9.37e-187 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
HHIGLKPN_01184 7.05e-157 - - - C - - - Zinc-binding dehydrogenase
HHIGLKPN_01185 1.47e-63 - - - S - - - Membrane
HHIGLKPN_01186 1.36e-114 - - - S - - - Membrane
HHIGLKPN_01187 2.03e-34 - - - I - - - carboxylic ester hydrolase activity
HHIGLKPN_01188 4.04e-81 - - - S - - - Alpha/beta hydrolase family
HHIGLKPN_01189 2.3e-42 bioY2 - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin synthase
HHIGLKPN_01190 1.11e-37 - - - S - - - HicB family
HHIGLKPN_01192 5.31e-78 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
HHIGLKPN_01193 2.73e-60 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
HHIGLKPN_01194 1.12e-90 - - - S - - - Nucleotidyl transferase AbiEii toxin, Type IV TA system
HHIGLKPN_01195 1.6e-251 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HHIGLKPN_01196 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HHIGLKPN_01197 4.02e-283 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HHIGLKPN_01198 6.96e-81 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
HHIGLKPN_01199 5.18e-272 - - - Q - - - Imidazolonepropionase and related amidohydrolases
HHIGLKPN_01200 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
HHIGLKPN_01201 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HHIGLKPN_01202 6.35e-277 - - - EGP ko:K08196,ko:K08369 - ko00000,ko02000 Major Facilitator
HHIGLKPN_01203 3.41e-78 ptsG 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HHIGLKPN_01204 4.72e-72 - - - - - - - -
HHIGLKPN_01205 4.7e-62 - - - - - - - -
HHIGLKPN_01206 1.19e-208 - 1.1.1.29 - CH ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHIGLKPN_01207 4.79e-168 - - - - - - - -
HHIGLKPN_01208 4.7e-111 - - - V - - - Beta-lactamase
HHIGLKPN_01209 8.65e-52 - - - K ko:K06977 - ko00000 acetyltransferase
HHIGLKPN_01210 3.44e-127 - - - - - - - -
HHIGLKPN_01211 8.26e-60 - - - - - - - -
HHIGLKPN_01212 2.06e-52 - - - - - - - -
HHIGLKPN_01213 2.36e-77 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
HHIGLKPN_01214 1.37e-249 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
HHIGLKPN_01215 4.22e-169 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
HHIGLKPN_01216 2.73e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
HHIGLKPN_01217 7.24e-22 - - - - - - - -
HHIGLKPN_01218 3.21e-27 - - - - - - - -
HHIGLKPN_01219 5.23e-31 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HHIGLKPN_01220 2.4e-146 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HHIGLKPN_01221 1.76e-160 - - - - - - - -
HHIGLKPN_01222 7e-304 - - - S - - - response to antibiotic
HHIGLKPN_01223 2.9e-172 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HHIGLKPN_01224 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HHIGLKPN_01225 1.39e-60 aspD 4.1.1.12 - E ko:K09758 ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230 ko00000,ko00001,ko01000 Aminotransferase class I and II
HHIGLKPN_01226 6.3e-110 - - - K - - - Domain of unknown function (DUF1836)
HHIGLKPN_01227 8.75e-198 yitS - - S - - - EDD domain protein, DegV family
HHIGLKPN_01230 2.22e-192 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HHIGLKPN_01231 5.88e-72 - - - - - - - -
HHIGLKPN_01232 6.12e-179 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HHIGLKPN_01233 3.19e-93 mgtC3 - - S ko:K07507 - ko00000,ko02000 MgtC family
HHIGLKPN_01234 1.36e-58 mgtC3 - - S ko:K07507 - ko00000,ko02000 MgtC family
HHIGLKPN_01235 3.87e-12 - - - C - - - FMN-dependent dehydrogenase
HHIGLKPN_01236 4.21e-208 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HHIGLKPN_01237 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HHIGLKPN_01238 8.43e-73 yheA - - S - - - Belongs to the UPF0342 family
HHIGLKPN_01239 2.37e-291 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
HHIGLKPN_01240 0.0 yhaN - - L - - - AAA domain
HHIGLKPN_01241 1.16e-241 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
HHIGLKPN_01242 4.1e-67 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
HHIGLKPN_01243 3.74e-115 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HHIGLKPN_01244 1.43e-221 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
HHIGLKPN_01245 1.55e-79 - - - - - - - -
HHIGLKPN_01246 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HHIGLKPN_01247 4.97e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HHIGLKPN_01248 7.41e-313 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HHIGLKPN_01249 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HHIGLKPN_01250 6.43e-283 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HHIGLKPN_01251 7.46e-279 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HHIGLKPN_01252 3.02e-46 - - - S - - - reductase
HHIGLKPN_01253 1.77e-95 - - - S - - - reductase
HHIGLKPN_01254 1.58e-110 yxeH - - S - - - hydrolase
HHIGLKPN_01255 9.08e-34 yxeH - - S - - - hydrolase
HHIGLKPN_01256 6.37e-14 yxeH - - S - - - hydrolase
HHIGLKPN_01257 1.17e-18 gyaR 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHIGLKPN_01258 1.89e-99 gyaR 1.1.1.26, 1.1.1.399, 1.1.1.95 - CH ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHIGLKPN_01259 1.42e-56 gyaR 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHIGLKPN_01260 1.37e-94 - - - S - - - Iron-sulphur cluster biosynthesis
HHIGLKPN_01262 1.05e-162 - - - F - - - NUDIX domain
HHIGLKPN_01263 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HHIGLKPN_01264 1.97e-140 pncA - - Q - - - Isochorismatase family
HHIGLKPN_01265 8.72e-66 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
HHIGLKPN_01266 1.08e-181 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
HHIGLKPN_01268 7.8e-149 - - - K ko:K03492 - ko00000,ko03000 UTRA domain
HHIGLKPN_01269 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HHIGLKPN_01270 1.08e-216 ydhF - - S - - - Aldo keto reductase
HHIGLKPN_01271 3.12e-222 iunH 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
HHIGLKPN_01272 9.99e-72 - - - - - - - -
HHIGLKPN_01273 2.56e-14 - - - - - - - -
HHIGLKPN_01274 8.69e-49 - - - C - - - FMN_bind
HHIGLKPN_01275 0.0 - - - I - - - Protein of unknown function (DUF2974)
HHIGLKPN_01276 4e-140 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
HHIGLKPN_01277 4.04e-265 pbpX1 - - V - - - Beta-lactamase
HHIGLKPN_01278 1.74e-252 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HHIGLKPN_01279 1.74e-271 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HHIGLKPN_01280 2.69e-182 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HHIGLKPN_01281 2.2e-223 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HHIGLKPN_01282 9.43e-280 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HHIGLKPN_01283 2.94e-108 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HHIGLKPN_01284 3.8e-316 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HHIGLKPN_01285 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HHIGLKPN_01286 2.34e-241 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HHIGLKPN_01287 0.0 potE - - E - - - Amino Acid
HHIGLKPN_01288 1.07e-134 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HHIGLKPN_01289 1.1e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HHIGLKPN_01290 5.53e-276 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HHIGLKPN_01291 5.52e-285 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HHIGLKPN_01292 3.27e-192 - - - - - - - -
HHIGLKPN_01293 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHIGLKPN_01294 1.48e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HHIGLKPN_01295 4.42e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HHIGLKPN_01296 2.46e-224 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HHIGLKPN_01297 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HHIGLKPN_01298 1.63e-128 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
HHIGLKPN_01299 7.89e-245 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HHIGLKPN_01300 6.77e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HHIGLKPN_01301 2.48e-124 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
HHIGLKPN_01302 1.72e-71 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
HHIGLKPN_01303 2.72e-263 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HHIGLKPN_01304 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HHIGLKPN_01305 5.41e-129 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HHIGLKPN_01306 9e-46 ykzG - - S - - - Belongs to the UPF0356 family
HHIGLKPN_01307 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHIGLKPN_01308 7.34e-35 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HHIGLKPN_01309 4.59e-135 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HHIGLKPN_01310 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HHIGLKPN_01311 1.24e-126 - - - S - - - repeat protein
HHIGLKPN_01312 3.18e-161 pgm - - G - - - Phosphoglycerate mutase family
HHIGLKPN_01313 1.56e-278 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HHIGLKPN_01314 4.07e-74 XK27_04120 - - S - - - Putative amino acid metabolism
HHIGLKPN_01315 1.33e-275 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HHIGLKPN_01316 3.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HHIGLKPN_01317 1.28e-56 - - - - - - - -
HHIGLKPN_01318 6.29e-135 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HHIGLKPN_01319 1.15e-43 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
HHIGLKPN_01320 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HHIGLKPN_01321 3.52e-150 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
HHIGLKPN_01322 8.08e-192 ylmH - - S - - - S4 domain protein
HHIGLKPN_01323 5.07e-62 yggT - - S ko:K02221 - ko00000,ko02044 YGGT family
HHIGLKPN_01324 1.26e-95 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HHIGLKPN_01325 1.93e-262 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HHIGLKPN_01326 8.51e-295 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HHIGLKPN_01327 1.4e-181 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HHIGLKPN_01328 4.23e-268 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HHIGLKPN_01329 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HHIGLKPN_01330 3.96e-227 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HHIGLKPN_01331 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HHIGLKPN_01332 2.2e-70 ftsL - - D - - - Cell division protein FtsL
HHIGLKPN_01333 3.29e-234 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HHIGLKPN_01334 3.81e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HHIGLKPN_01335 1.27e-22 - - - S - - - Transglycosylase associated protein
HHIGLKPN_01336 1.87e-134 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
HHIGLKPN_01337 1.8e-21 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
HHIGLKPN_01338 2.53e-31 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
HHIGLKPN_01339 5.77e-102 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HHIGLKPN_01340 2.4e-102 - - - K - - - Transcriptional regulator
HHIGLKPN_01341 3.02e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HHIGLKPN_01342 1.53e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHIGLKPN_01343 1.66e-215 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
HHIGLKPN_01344 8.92e-164 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HHIGLKPN_01345 8.97e-293 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HHIGLKPN_01346 5.23e-102 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HHIGLKPN_01347 1.64e-94 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
HHIGLKPN_01348 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
HHIGLKPN_01349 5.09e-202 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HHIGLKPN_01350 2.6e-183 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
HHIGLKPN_01351 8.96e-173 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HHIGLKPN_01352 2.25e-241 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HHIGLKPN_01353 1.15e-19 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HHIGLKPN_01354 1.05e-313 - - - S ko:K12941 - ko00000,ko01002 Peptidase dimerisation domain
HHIGLKPN_01355 9.98e-180 - - - S - - - Protein of unknown function (DUF3100)
HHIGLKPN_01356 4.07e-107 - - - S - - - An automated process has identified a potential problem with this gene model
HHIGLKPN_01357 4.32e-46 - - - - - - - -
HHIGLKPN_01358 1.4e-104 - - - S - - - Pyridoxamine 5'-phosphate oxidase
HHIGLKPN_01359 2.66e-219 yobV3 - - K - - - WYL domain
HHIGLKPN_01360 2.4e-89 - - - S - - - pyridoxamine 5-phosphate
HHIGLKPN_01361 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
HHIGLKPN_01362 6.85e-26 adh1 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HHIGLKPN_01363 8.38e-62 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
HHIGLKPN_01364 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
HHIGLKPN_01365 2.95e-43 - - - C - - - Heavy-metal-associated domain
HHIGLKPN_01366 3.92e-117 dpsB - - P - - - Belongs to the Dps family
HHIGLKPN_01367 1.39e-141 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
HHIGLKPN_01368 1.46e-73 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HHIGLKPN_01369 6.75e-40 - - - - - - - -
HHIGLKPN_01370 3.21e-23 - - - - - - - -
HHIGLKPN_01371 9e-226 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HHIGLKPN_01372 3.67e-310 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HHIGLKPN_01373 5.68e-117 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HHIGLKPN_01374 3.92e-217 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
HHIGLKPN_01375 1.14e-312 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HHIGLKPN_01376 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHIGLKPN_01377 8.1e-200 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
HHIGLKPN_01378 7.68e-173 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHIGLKPN_01379 1.3e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HHIGLKPN_01380 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
HHIGLKPN_01381 9.85e-49 yozE - - S - - - Belongs to the UPF0346 family
HHIGLKPN_01382 3.37e-190 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
HHIGLKPN_01383 4.24e-151 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
HHIGLKPN_01384 6.97e-153 cps3J - - M - - - Domain of unknown function (DUF4422)
HHIGLKPN_01385 1.12e-124 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
HHIGLKPN_01386 2.32e-186 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HHIGLKPN_01387 1.93e-156 ywqD - - D - - - Capsular exopolysaccharide family
HHIGLKPN_01388 2.43e-187 epsB - - M - - - biosynthesis protein
HHIGLKPN_01389 2.46e-248 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HHIGLKPN_01390 7.83e-284 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HHIGLKPN_01393 2.86e-198 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
HHIGLKPN_01394 5.51e-69 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HHIGLKPN_01395 2.41e-314 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
HHIGLKPN_01396 4.82e-55 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
HHIGLKPN_01397 7.07e-38 tnpR - - L - - - Resolvase, N terminal domain
HHIGLKPN_01398 9.3e-56 ymdB - - S - - - Macro domain protein
HHIGLKPN_01399 5.67e-197 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HHIGLKPN_01400 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHIGLKPN_01401 1.29e-280 malE - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHIGLKPN_01402 3.19e-263 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HHIGLKPN_01403 2.04e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HHIGLKPN_01404 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HHIGLKPN_01405 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HHIGLKPN_01406 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
HHIGLKPN_01407 4.29e-55 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHIGLKPN_01408 9.53e-286 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
HHIGLKPN_01409 4.13e-24 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
HHIGLKPN_01411 2.21e-46 - - - - - - - -
HHIGLKPN_01413 2.8e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HHIGLKPN_01414 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HHIGLKPN_01415 8.07e-314 yycH - - S - - - YycH protein
HHIGLKPN_01416 1.18e-188 yycI - - S - - - YycH protein
HHIGLKPN_01417 2.14e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
HHIGLKPN_01418 1.18e-274 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
HHIGLKPN_01419 2.23e-117 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HHIGLKPN_01420 3.99e-49 - - - K - - - Helix-turn-helix domain
HHIGLKPN_01441 1.19e-279 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
HHIGLKPN_01442 1.75e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HHIGLKPN_01443 4.59e-226 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HHIGLKPN_01444 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HHIGLKPN_01445 1.3e-40 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HHIGLKPN_01446 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HHIGLKPN_01447 4.52e-101 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HHIGLKPN_01448 1.26e-117 - - - - - - - -
HHIGLKPN_01451 4.97e-250 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HHIGLKPN_01452 2.3e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HHIGLKPN_01453 0.0 potE - - E - - - Amino Acid
HHIGLKPN_01454 3.43e-51 - - - - - - - -
HHIGLKPN_01455 1.06e-73 - - - - - - - -
HHIGLKPN_01456 3.97e-109 - - - - - - - -
HHIGLKPN_01457 3.39e-51 - - - - - - - -
HHIGLKPN_01458 6.76e-07 - - - - - - - -
HHIGLKPN_01459 2.48e-161 - - - S - - - L-ascorbic acid biosynthetic process
HHIGLKPN_01460 3.6e-92 - - - O - - - OsmC-like protein
HHIGLKPN_01461 7.52e-264 - - - EGP - - - Major Facilitator Superfamily
HHIGLKPN_01462 2.8e-147 sptS - - T - - - Histidine kinase
HHIGLKPN_01463 1.37e-62 sptS - - T - - - Histidine kinase
HHIGLKPN_01464 6.18e-105 dltr - - K - - - response regulator
HHIGLKPN_01465 9.52e-211 - - - S - - - SLAP domain
HHIGLKPN_01466 1.77e-72 - - - S - - - Bacteriocin helveticin-J
HHIGLKPN_01467 4.78e-307 srrA1 - - G ko:K02027,ko:K17244 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHIGLKPN_01468 2.85e-206 - - - C - - - Domain of unknown function (DUF4931)
HHIGLKPN_01469 8.52e-215 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHIGLKPN_01470 3.83e-163 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HHIGLKPN_01471 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HHIGLKPN_01472 3.01e-224 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
HHIGLKPN_01473 1.06e-170 gntR - - K - - - UbiC transcription regulator-associated domain protein
HHIGLKPN_01475 3.54e-156 - - - S - - - Protein of unknown function (DUF975)
HHIGLKPN_01476 2.81e-22 - - - - - - - -
HHIGLKPN_01477 6.79e-44 - - - - - - - -
HHIGLKPN_01478 6.93e-39 - - - - - - - -
HHIGLKPN_01479 4.44e-160 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HHIGLKPN_01480 5.67e-11 - - - - - - - -
HHIGLKPN_01482 7.96e-223 pbpX2 - - V - - - Beta-lactamase
HHIGLKPN_01483 2.58e-313 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HHIGLKPN_01484 2.46e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHIGLKPN_01485 5.79e-311 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
HHIGLKPN_01486 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHIGLKPN_01487 6.46e-27 - - - S - - - D-Ala-teichoic acid biosynthesis protein
HHIGLKPN_01488 2e-67 - - - - - - - -
HHIGLKPN_01489 8.61e-273 - - - S - - - Membrane
HHIGLKPN_01490 6.18e-33 ykuL - - S - - - IMP dehydrogenase activity
HHIGLKPN_01492 4.22e-236 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HHIGLKPN_01493 5.79e-311 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
HHIGLKPN_01494 6.86e-154 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HHIGLKPN_01495 3.13e-141 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HHIGLKPN_01496 1.95e-137 - - - - - - - -
HHIGLKPN_01497 1.78e-208 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HHIGLKPN_01498 1.36e-143 - - - S - - - Peptidase family M23
HHIGLKPN_01499 1.34e-196 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HHIGLKPN_01500 4.83e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HHIGLKPN_01501 5.12e-91 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
HHIGLKPN_01502 7.92e-221 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
HHIGLKPN_01503 4.18e-128 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HHIGLKPN_01504 4.06e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HHIGLKPN_01505 2.79e-175 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HHIGLKPN_01506 2.22e-229 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HHIGLKPN_01507 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HHIGLKPN_01508 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HHIGLKPN_01509 2.88e-251 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HHIGLKPN_01510 3.44e-160 - - - S - - - Peptidase family M23
HHIGLKPN_01511 4.56e-89 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HHIGLKPN_01512 7.43e-160 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HHIGLKPN_01513 3.45e-197 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HHIGLKPN_01514 6.01e-309 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HHIGLKPN_01515 7.06e-81 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
HHIGLKPN_01516 3.13e-160 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HHIGLKPN_01517 9.64e-187 - - - - - - - -
HHIGLKPN_01518 2.79e-188 - - - - - - - -
HHIGLKPN_01519 1.19e-177 - - - - - - - -
HHIGLKPN_01520 3.03e-13 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HHIGLKPN_01521 5.68e-146 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HHIGLKPN_01522 7.83e-38 - - - - - - - -
HHIGLKPN_01523 7.35e-134 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HHIGLKPN_01524 1.83e-180 - - - - - - - -
HHIGLKPN_01525 3.94e-225 - - - - - - - -
HHIGLKPN_01526 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
HHIGLKPN_01527 1.03e-237 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HHIGLKPN_01528 4.69e-261 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
HHIGLKPN_01529 3.03e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
HHIGLKPN_01530 1.53e-214 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
HHIGLKPN_01531 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HHIGLKPN_01532 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HHIGLKPN_01533 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HHIGLKPN_01534 3.49e-116 ypmB - - S - - - Protein conserved in bacteria
HHIGLKPN_01535 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HHIGLKPN_01536 1.39e-148 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
HHIGLKPN_01537 2.95e-146 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HHIGLKPN_01538 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
HHIGLKPN_01539 1.07e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HHIGLKPN_01540 1.13e-137 ypsA - - S - - - Belongs to the UPF0398 family
HHIGLKPN_01541 1.29e-91 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HHIGLKPN_01542 5.4e-274 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HHIGLKPN_01543 2.34e-254 cpdA - - S - - - Calcineurin-like phosphoesterase
HHIGLKPN_01544 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HHIGLKPN_01545 7.77e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HHIGLKPN_01546 6.46e-212 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HHIGLKPN_01547 1.44e-255 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HHIGLKPN_01548 0.0 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HHIGLKPN_01549 6.23e-244 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HHIGLKPN_01550 2.62e-239 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
HHIGLKPN_01551 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HHIGLKPN_01552 1.25e-241 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HHIGLKPN_01553 1.81e-29 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HHIGLKPN_01554 2.5e-59 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HHIGLKPN_01555 3.11e-141 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HHIGLKPN_01556 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HHIGLKPN_01557 6.04e-113 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
HHIGLKPN_01558 2.71e-53 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
HHIGLKPN_01559 9.7e-133 - - - E - - - GDSL-like Lipase/Acylhydrolase
HHIGLKPN_01560 7.88e-219 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HHIGLKPN_01561 5.59e-134 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HHIGLKPN_01562 7.39e-311 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHIGLKPN_01563 1.81e-88 - - - S - - - Peptidase propeptide and YPEB domain
HHIGLKPN_01564 1.82e-18 - - - S - - - Peptidase propeptide and YPEB domain
HHIGLKPN_01565 5.44e-88 yybA - - K - - - Transcriptional regulator
HHIGLKPN_01566 4.17e-111 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HHIGLKPN_01567 5.86e-106 - - - S - - - Peptidase propeptide and YPEB domain
HHIGLKPN_01568 7.59e-123 - - - F - - - Nucleoside 2-deoxyribosyltransferase
HHIGLKPN_01569 2.42e-238 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HHIGLKPN_01570 2.91e-229 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HHIGLKPN_01571 0.0 - - - V - - - ABC transporter transmembrane region
HHIGLKPN_01572 1.51e-154 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HHIGLKPN_01573 7.3e-248 - - - S - - - DUF218 domain
HHIGLKPN_01574 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HHIGLKPN_01575 1.89e-126 - - - S - - - ECF transporter, substrate-specific component
HHIGLKPN_01576 8.48e-204 - - - S - - - Aldo/keto reductase family
HHIGLKPN_01577 4.67e-173 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HHIGLKPN_01578 3.09e-128 - - - K - - - rpiR family
HHIGLKPN_01579 7.31e-184 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HHIGLKPN_01580 1.04e-91 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Beta-lactamase
HHIGLKPN_01581 4.46e-72 - - - S - - - Protein of unknown function (DUF3397)
HHIGLKPN_01582 1.09e-18 - - - S - - - Protein of unknown function (DUF4044)
HHIGLKPN_01583 8.04e-124 mreD - - - ko:K03571 - ko00000,ko03036 -
HHIGLKPN_01584 7.09e-190 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HHIGLKPN_01585 1.01e-226 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
HHIGLKPN_01586 3.32e-148 radC - - L ko:K03630 - ko00000 DNA repair protein
HHIGLKPN_01587 4.33e-162 - - - S - - - Haloacid dehalogenase-like hydrolase
HHIGLKPN_01588 8.83e-303 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HHIGLKPN_01589 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HHIGLKPN_01590 2.35e-126 - - - - ko:K19167 - ko00000,ko02048 -
HHIGLKPN_01591 1.13e-114 - - - S - - - Bacterial membrane protein, YfhO
HHIGLKPN_01592 6.81e-234 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
HHIGLKPN_01593 9.19e-312 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter
HHIGLKPN_01594 2.99e-242 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HHIGLKPN_01595 2.16e-213 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HHIGLKPN_01596 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HHIGLKPN_01597 1.52e-268 eriC - - P ko:K03281 - ko00000 chloride
HHIGLKPN_01598 1.08e-52 - - - O - - - Matrixin
HHIGLKPN_01599 2.92e-61 - - - S - - - Domain of unknown function (DUF4160)
HHIGLKPN_01600 2.15e-48 - - - S - - - Transglycosylase associated protein
HHIGLKPN_01601 7.24e-30 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HHIGLKPN_01602 2.49e-116 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HHIGLKPN_01603 5.82e-35 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HHIGLKPN_01604 1.1e-69 - - - - - - - -
HHIGLKPN_01605 5.51e-140 XK27_00160 - - S - - - Domain of unknown function (DUF5052)
HHIGLKPN_01606 2.77e-114 flaR - - F - - - topology modulation protein
HHIGLKPN_01607 3.71e-95 - - - - - - - -
HHIGLKPN_01608 5.71e-262 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
HHIGLKPN_01609 3.06e-205 - - - S - - - EDD domain protein, DegV family
HHIGLKPN_01610 6.77e-53 - - - - - - - -
HHIGLKPN_01611 0.0 FbpA - - K - - - Fibronectin-binding protein
HHIGLKPN_01612 2.72e-101 - - - - - - - -
HHIGLKPN_01613 2.96e-41 - - - - - - - -
HHIGLKPN_01614 1.94e-15 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHIGLKPN_01615 3.75e-98 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
HHIGLKPN_01616 6.65e-129 - - - - - - - -
HHIGLKPN_01617 0.0 - - - S - - - O-antigen ligase like membrane protein
HHIGLKPN_01618 5.24e-41 - - - - - - - -
HHIGLKPN_01619 3.81e-123 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase homologues.
HHIGLKPN_01620 1.49e-121 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
HHIGLKPN_01621 5.54e-36 - - - S ko:K06921 - ko00000 Archaea bacterial proteins of unknown function
HHIGLKPN_01622 1.59e-72 - - - S ko:K06921 - ko00000 Archaea bacterial proteins of unknown function
HHIGLKPN_01623 2.15e-137 - - - L - - - Resolvase, N terminal domain
HHIGLKPN_01624 0.0 - - - L - - - Probable transposase
HHIGLKPN_01625 3.43e-164 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
HHIGLKPN_01626 1.17e-168 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
HHIGLKPN_01627 6.64e-146 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HHIGLKPN_01628 1.21e-40 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HHIGLKPN_01630 6.04e-203 - - - V - - - ABC transporter transmembrane region
HHIGLKPN_01632 1.49e-312 - 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HHIGLKPN_01633 0.0 - - - L - - - Type III restriction enzyme, res subunit
HHIGLKPN_01634 5.99e-31 - - - L - - - DNA methylAse
HHIGLKPN_01635 7.15e-52 - - - - - - - -
HHIGLKPN_01636 1.53e-105 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HHIGLKPN_01637 4.53e-27 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HHIGLKPN_01638 2.29e-196 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HHIGLKPN_01639 5.12e-71 yitW - - S - - - Iron-sulfur cluster assembly protein
HHIGLKPN_01641 6.36e-16 - - - M - - - NlpC/P60 family
HHIGLKPN_01642 6.69e-28 - - - M - - - NlpC/P60 family
HHIGLKPN_01643 1.35e-82 - - - M - - - NlpC/P60 family
HHIGLKPN_01644 2.83e-146 - - - G - - - Peptidase_C39 like family
HHIGLKPN_01645 4.61e-36 - - - - - - - -
HHIGLKPN_01647 2.86e-40 - - - - - - - -
HHIGLKPN_01649 8.31e-274 - - - S - - - SLAP domain
HHIGLKPN_01650 4.14e-296 - - - S - - - Domain of unknown function (DUF3883)
HHIGLKPN_01651 4.44e-238 - - - S - - - Putative peptidoglycan binding domain
HHIGLKPN_01652 1.58e-33 - - - - - - - -
HHIGLKPN_01653 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HHIGLKPN_01654 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
HHIGLKPN_01656 2.79e-77 lysM - - M - - - LysM domain
HHIGLKPN_01657 8.23e-222 - - - - - - - -
HHIGLKPN_01658 4.85e-288 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HHIGLKPN_01659 5.06e-46 - - - L - - - PFAM transposase, IS4 family protein
HHIGLKPN_01660 3.46e-241 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HHIGLKPN_01661 3.9e-191 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HHIGLKPN_01662 5.87e-229 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HHIGLKPN_01663 9.21e-50 - - - - - - - -
HHIGLKPN_01664 2.93e-236 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HHIGLKPN_01665 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HHIGLKPN_01666 3.81e-123 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HHIGLKPN_01667 4.17e-172 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
HHIGLKPN_01668 1.01e-310 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
HHIGLKPN_01669 1.39e-151 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
HHIGLKPN_01670 3.21e-267 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
HHIGLKPN_01671 4.31e-286 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HHIGLKPN_01672 8.88e-248 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HHIGLKPN_01673 3e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HHIGLKPN_01674 3.69e-187 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
HHIGLKPN_01675 1.14e-170 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HHIGLKPN_01676 3.06e-300 ymfH - - S - - - Peptidase M16
HHIGLKPN_01677 2.34e-288 ymfF - - S - - - Peptidase M16 inactive domain protein
HHIGLKPN_01678 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HHIGLKPN_01679 4.46e-90 WQ51_03320 - - S - - - Protein of unknown function (DUF1149)
HHIGLKPN_01680 1.23e-135 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HHIGLKPN_01681 3.48e-269 XK27_05220 - - S - - - AI-2E family transporter
HHIGLKPN_01682 1.35e-85 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
HHIGLKPN_01683 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
HHIGLKPN_01684 1.75e-256 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HHIGLKPN_01685 6.52e-59 - - - S - - - SNARE associated Golgi protein
HHIGLKPN_01686 5.71e-38 - - - S - - - SNARE associated Golgi protein
HHIGLKPN_01687 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HHIGLKPN_01688 4.97e-218 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HHIGLKPN_01689 4.35e-198 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HHIGLKPN_01690 1.15e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HHIGLKPN_01691 8.48e-145 - - - S - - - CYTH
HHIGLKPN_01692 5.3e-144 yjbH - - Q - - - Thioredoxin
HHIGLKPN_01693 1.53e-203 coiA - - S ko:K06198 - ko00000 Competence protein
HHIGLKPN_01694 3.26e-172 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HHIGLKPN_01695 1.08e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HHIGLKPN_01696 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHIGLKPN_01697 1.29e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
HHIGLKPN_01698 5.25e-37 - - - - - - - -
HHIGLKPN_01699 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
HHIGLKPN_01700 4.17e-60 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
HHIGLKPN_01701 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HHIGLKPN_01702 1.2e-205 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
HHIGLKPN_01703 2.6e-96 - - - - - - - -
HHIGLKPN_01704 1.05e-112 - - - - - - - -
HHIGLKPN_01705 2.89e-185 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
HHIGLKPN_01706 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHIGLKPN_01707 2.06e-127 ybcH - - D ko:K06889 - ko00000 Alpha beta
HHIGLKPN_01711 3.44e-123 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HHIGLKPN_01712 1.54e-308 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HHIGLKPN_01713 1.36e-178 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HHIGLKPN_01714 6.05e-68 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HHIGLKPN_01715 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HHIGLKPN_01717 1.77e-282 - - - E - - - IrrE N-terminal-like domain
HHIGLKPN_01718 3.18e-37 - - - S - - - Domain of unknown function (DUF4411)
HHIGLKPN_01719 6.66e-271 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
HHIGLKPN_01720 5.45e-48 - - - - - - - -
HHIGLKPN_01721 3.1e-44 - - - - - - - -
HHIGLKPN_01722 3.38e-173 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HHIGLKPN_01723 4.39e-160 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
HHIGLKPN_01724 9.66e-161 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
HHIGLKPN_01725 2.7e-89 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
HHIGLKPN_01726 1.39e-121 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HHIGLKPN_01727 0.0 - - - - - - - -
HHIGLKPN_01728 7.07e-106 - - - - - - - -
HHIGLKPN_01729 5.83e-140 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HHIGLKPN_01730 9.99e-86 - - - S - - - ASCH domain
HHIGLKPN_01731 2.97e-71 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 lactoylglutathione lyase activity
HHIGLKPN_01732 2.46e-29 - - - S - - - Domain of unknown function (DUF4298)
HHIGLKPN_01733 1.16e-96 - - - L - - - Transposase DDE domain
HHIGLKPN_01734 1.06e-44 - - - L - - - DnaB-like helicase C terminal domain
HHIGLKPN_01735 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HHIGLKPN_01736 6.51e-106 - - - - - - - -
HHIGLKPN_01737 1.38e-33 - - - - - - - -
HHIGLKPN_01738 4.13e-148 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
HHIGLKPN_01739 9.35e-152 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
HHIGLKPN_01740 9.75e-174 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HHIGLKPN_01741 2.63e-207 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HHIGLKPN_01742 3.23e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
HHIGLKPN_01743 1.43e-54 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HHIGLKPN_01744 8.73e-120 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HHIGLKPN_01745 8.71e-46 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HHIGLKPN_01746 3.33e-10 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HHIGLKPN_01747 3.36e-61 - - - - - - - -
HHIGLKPN_01749 6.28e-124 - - - S - - - Cysteine-rich secretory protein family
HHIGLKPN_01750 8.46e-65 - - - - - - - -
HHIGLKPN_01751 2.65e-260 - - - G - - - Major Facilitator Superfamily
HHIGLKPN_01752 5.54e-69 - - - - - - - -
HHIGLKPN_01753 3.36e-105 - - - S - - - Threonine/Serine exporter, ThrE
HHIGLKPN_01754 1.14e-177 - - - S - - - Putative threonine/serine exporter
HHIGLKPN_01755 0.0 - - - S - - - ABC transporter
HHIGLKPN_01756 2.34e-74 - - - - - - - -
HHIGLKPN_01757 3.26e-128 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HHIGLKPN_01758 2.27e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HHIGLKPN_01759 2.18e-286 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HHIGLKPN_01760 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HHIGLKPN_01761 1.45e-54 - - - S - - - Fic/DOC family
HHIGLKPN_01762 2.59e-86 - - - L - - - Transposase
HHIGLKPN_01763 2.87e-53 - - - L - - - PFAM transposase, IS4 family protein
HHIGLKPN_01764 4.43e-105 - - - L - - - PFAM transposase, IS4 family protein
HHIGLKPN_01765 4.92e-124 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
HHIGLKPN_01766 1.81e-273 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HHIGLKPN_01767 6.74e-214 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HHIGLKPN_01768 2.04e-27 - - - - - - - -
HHIGLKPN_01769 1.31e-121 - - - - - - - -
HHIGLKPN_01770 2.51e-31 - - - S - - - Small integral membrane protein (DUF2273)
HHIGLKPN_01771 6.49e-110 asp1 - - S - - - Asp23 family, cell envelope-related function
HHIGLKPN_01772 3.42e-41 - - - S - - - Transglycosylase associated protein
HHIGLKPN_01773 1.14e-23 - - - - - - - -
HHIGLKPN_01774 3.46e-57 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HHIGLKPN_01776 2.37e-189 aspD 4.1.1.12 - E ko:K09758 ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230 ko00000,ko00001,ko01000 Aminotransferase
HHIGLKPN_01777 1.15e-310 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
HHIGLKPN_01778 3.11e-107 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HHIGLKPN_01779 5.82e-33 - - - S - - - response to antibiotic
HHIGLKPN_01780 1.35e-51 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HHIGLKPN_01781 8.79e-179 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HHIGLKPN_01782 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 DEAD/DEAH box helicase
HHIGLKPN_01783 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
HHIGLKPN_01784 4.51e-72 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HHIGLKPN_01785 1.58e-66 - 3.1.21.3 - L ko:K01154 - ko00000,ko01000,ko02048 PFAM restriction modification system DNA specificity domain
HHIGLKPN_01786 4.25e-198 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 PFAM DNA methylase
HHIGLKPN_01787 1.2e-266 - - - L - - - Belongs to the 'phage' integrase family
HHIGLKPN_01788 6.69e-39 - - - - - - - -
HHIGLKPN_01789 1.33e-208 - - - EP - - - Plasmid replication protein
HHIGLKPN_01791 1.11e-81 - - - D - - - COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HHIGLKPN_01792 1.27e-21 - - - - - - - -
HHIGLKPN_01794 0.0 cadA - - P - - - P-type ATPase
HHIGLKPN_01795 4.3e-258 napA - - P - - - Sodium/hydrogen exchanger family
HHIGLKPN_01796 9e-66 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
HHIGLKPN_01797 5.58e-63 yoeB - - S ko:K19158 - ko00000,ko01000,ko02048 YoeB-like toxin of bacterial type II toxin-antitoxin system
HHIGLKPN_01798 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
HHIGLKPN_01799 1.09e-106 - - - S - - - Putative adhesin
HHIGLKPN_01800 9.15e-200 mutR - - K - - - Helix-turn-helix XRE-family like proteins
HHIGLKPN_01801 1.77e-61 - - - - - - - -
HHIGLKPN_01802 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
HHIGLKPN_01803 1.28e-241 flp - - V - - - Beta-lactamase
HHIGLKPN_01804 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HHIGLKPN_01805 3.44e-58 - - - - - - - -
HHIGLKPN_01806 7.54e-174 - - - - - - - -
HHIGLKPN_01807 1.6e-114 - - - K - - - Acetyltransferase (GNAT) domain
HHIGLKPN_01808 3.57e-84 - - - S - - - Protein of unknown function (DUF3021)
HHIGLKPN_01809 7.65e-101 - - - K - - - LytTr DNA-binding domain
HHIGLKPN_01810 1.66e-56 - - - - - - - -
HHIGLKPN_01811 1.35e-161 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
HHIGLKPN_01812 1.44e-31 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HHIGLKPN_01813 8.01e-68 - - - - - - - -
HHIGLKPN_01814 3.37e-190 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
HHIGLKPN_01815 3.01e-292 - - - L ko:K07478 - ko00000 AAA C-terminal domain
HHIGLKPN_01816 7.55e-44 - - - - - - - -
HHIGLKPN_01817 4e-88 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
HHIGLKPN_01818 8.62e-109 kptA - - H ko:K07559 - ko00000,ko01000,ko03016 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HHIGLKPN_01819 8.81e-82 - - - S - - - Abi-like protein
HHIGLKPN_01821 1.35e-160 - - - S ko:K07045 - ko00000 Amidohydrolase
HHIGLKPN_01822 2.61e-133 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HHIGLKPN_01823 4.03e-105 - - - G - - - Antibiotic biosynthesis monooxygenase
HHIGLKPN_01824 4.34e-26 - - - G - - - Antibiotic biosynthesis monooxygenase
HHIGLKPN_01825 5.45e-37 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
HHIGLKPN_01826 1.03e-91 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
HHIGLKPN_01827 1.32e-144 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
HHIGLKPN_01828 2.95e-139 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
HHIGLKPN_01829 1.89e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HHIGLKPN_01830 2.08e-204 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HHIGLKPN_01831 6.18e-159 - - - L - - - Helix-turn-helix domain
HHIGLKPN_01832 6.96e-157 - - - L ko:K07497 - ko00000 hmm pf00665
HHIGLKPN_01834 1.36e-151 - - - L - - - Integrase
HHIGLKPN_01836 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HHIGLKPN_01837 4.35e-120 - - - K - - - Acetyltransferase (GNAT) family
HHIGLKPN_01838 4.54e-76 - - - S - - - Alpha beta hydrolase
HHIGLKPN_01839 1.97e-75 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
HHIGLKPN_01840 9.44e-184 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
HHIGLKPN_01841 3.4e-61 - 1.1.1.3 - T ko:K00003,ko:K07166 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 phosphoserine phosphatase activity
HHIGLKPN_01842 5.61e-108 - - - K - - - Bacterial regulatory proteins, tetR family
HHIGLKPN_01843 1.72e-140 - - - K ko:K09705 - ko00000 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HHIGLKPN_01844 1.63e-48 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HHIGLKPN_01845 2.32e-61 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HHIGLKPN_01846 1.57e-92 - - - K - - - COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HHIGLKPN_01847 5.36e-101 - - - K - - - COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HHIGLKPN_01848 2.62e-121 - - - K - - - acetyltransferase
HHIGLKPN_01849 9.82e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HHIGLKPN_01850 2.94e-24 - - - - - - - -
HHIGLKPN_01851 8.57e-43 - - - - - - - -
HHIGLKPN_01852 3.72e-22 snf - - KL - - - domain protein
HHIGLKPN_01853 2.89e-50 snf - - KL - - - domain protein
HHIGLKPN_01854 0.0 snf - - KL - - - domain protein
HHIGLKPN_01855 5.72e-120 snf - - KL - - - domain protein
HHIGLKPN_01856 1.02e-138 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HHIGLKPN_01857 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHIGLKPN_01858 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHIGLKPN_01859 4.25e-219 - - - K - - - Transcriptional regulator
HHIGLKPN_01860 3e-221 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
HHIGLKPN_01861 5.37e-143 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HHIGLKPN_01862 2.23e-73 - - - K - - - Helix-turn-helix domain
HHIGLKPN_01863 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
HHIGLKPN_01864 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
HHIGLKPN_01866 1.47e-21 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HHIGLKPN_01868 4.85e-20 - - - S - - - Phage derived protein Gp49-like (DUF891)
HHIGLKPN_01869 9.03e-55 - - - K - - - Helix-turn-helix XRE-family like proteins
HHIGLKPN_01870 1.06e-57 - - - - - - - -
HHIGLKPN_01871 7.75e-29 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
HHIGLKPN_01872 8.18e-81 - - - L - - - Probable transposase
HHIGLKPN_01873 1.12e-205 - - - L - - - Probable transposase
HHIGLKPN_01874 1.41e-18 - - - S - - - Fic/DOC family
HHIGLKPN_01875 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
HHIGLKPN_01876 2.93e-56 - - - S - - - MazG-like family
HHIGLKPN_01877 1.04e-105 - - - S - - - AAA domain
HHIGLKPN_01878 4.11e-82 - 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
HHIGLKPN_01879 6.7e-104 - - - S - - - F420-0:Gamma-glutamyl ligase
HHIGLKPN_01880 4.37e-153 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
HHIGLKPN_01881 2.97e-167 - - - F - - - Phosphorylase superfamily
HHIGLKPN_01882 8.73e-68 codA - - F - - - Cytidine and deoxycytidylate deaminase zinc-binding region
HHIGLKPN_01884 1.07e-104 - - - K - - - Acetyltransferase (GNAT) domain
HHIGLKPN_01885 4.74e-68 - - - - - - - -
HHIGLKPN_01886 7.23e-209 - - - - - - - -
HHIGLKPN_01887 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HHIGLKPN_01888 1.68e-163 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HHIGLKPN_01889 4.19e-198 - - - I - - - alpha/beta hydrolase fold
HHIGLKPN_01890 3.88e-140 - - - S - - - SNARE associated Golgi protein
HHIGLKPN_01891 2.29e-125 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HHIGLKPN_01892 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HHIGLKPN_01894 9.34e-246 - - - M - - - Glycosyl transferase family group 2
HHIGLKPN_01895 3.07e-50 - - - K - - - Helix-turn-helix XRE-family like proteins
HHIGLKPN_01896 1.15e-67 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
HHIGLKPN_01897 8.83e-57 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
HHIGLKPN_01898 2.97e-136 - - - L - - - Integrase
HHIGLKPN_01899 3.55e-67 - - - - - - - -
HHIGLKPN_01900 1.43e-106 - - - S - - - KAP family P-loop domain
HHIGLKPN_01901 3.43e-281 - - - KQ - - - helix_turn_helix, mercury resistance
HHIGLKPN_01902 8.13e-268 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HHIGLKPN_01903 5.33e-211 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HHIGLKPN_01904 1.93e-149 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HHIGLKPN_01905 3.08e-243 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HHIGLKPN_01907 0.0 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
HHIGLKPN_01909 1.28e-90 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HHIGLKPN_01910 1.61e-118 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
HHIGLKPN_01911 3.41e-131 - - - L - - - HTH-like domain
HHIGLKPN_01912 0.0 uvrA2 - - L - - - ABC transporter
HHIGLKPN_01913 5.89e-234 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HHIGLKPN_01914 2.13e-71 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
HHIGLKPN_01915 5.48e-82 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
HHIGLKPN_01916 5.94e-127 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
HHIGLKPN_01917 3.37e-291 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HHIGLKPN_01918 4.01e-79 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HHIGLKPN_01919 4.46e-81 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HHIGLKPN_01920 5.16e-155 - - - L - - - Transposase DDE domain
HHIGLKPN_01921 3.75e-165 - - - I - - - Acyl-transferase
HHIGLKPN_01922 2.1e-184 arbx - - M - - - Glycosyl transferase family 8
HHIGLKPN_01923 1.4e-234 - - - M - - - Glycosyl transferase family 8
HHIGLKPN_01924 1.06e-207 - - - M - - - Glycosyl transferase family 8
HHIGLKPN_01925 8.87e-212 arbZ - - I - - - Phosphate acyltransferases
HHIGLKPN_01926 2.49e-47 - - - S - - - Cytochrome b5
HHIGLKPN_01927 2.2e-141 - - - K - - - Transcriptional regulator, LysR family
HHIGLKPN_01928 1.93e-128 - - - K - - - LysR substrate binding domain
HHIGLKPN_01929 1.44e-52 - - - K - - - LysR substrate binding domain
HHIGLKPN_01931 4.12e-24 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HHIGLKPN_01932 3.16e-145 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HHIGLKPN_01933 1.94e-67 slpX - - S - - - SLAP domain
HHIGLKPN_01934 1.23e-270 slpX - - S - - - SLAP domain
HHIGLKPN_01935 7.06e-120 - - - - - - - -
HHIGLKPN_01938 2.88e-272 - - - - - - - -
HHIGLKPN_01939 8.97e-159 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
HHIGLKPN_01940 4.14e-81 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
HHIGLKPN_01941 1.26e-160 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HHIGLKPN_01942 1.54e-138 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HHIGLKPN_01943 1.9e-237 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HHIGLKPN_01944 8e-49 - - - - - - - -
HHIGLKPN_01945 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HHIGLKPN_01946 1.83e-197 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HHIGLKPN_01947 1.38e-170 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHIGLKPN_01948 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HHIGLKPN_01949 6.29e-190 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HHIGLKPN_01950 8.42e-74 yfhC - - C - - - nitroreductase
HHIGLKPN_01951 1.89e-99 - - - S - - - Domain of unknown function (DUF4767)
HHIGLKPN_01952 2.03e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HHIGLKPN_01953 6.8e-169 - - - S - - - Uncharacterised protein, DegV family COG1307
HHIGLKPN_01954 1.08e-127 - - - I - - - PAP2 superfamily
HHIGLKPN_01955 2.68e-40 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HHIGLKPN_01956 2.42e-156 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HHIGLKPN_01958 2.36e-74 - - - S - - - PFAM Uncharacterised protein family UPF0150
HHIGLKPN_01959 1.4e-312 yifK - - E ko:K03293 - ko00000 Amino acid permease
HHIGLKPN_01960 6.71e-242 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HHIGLKPN_01961 1.35e-123 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HHIGLKPN_01962 7.3e-22 ps301 - - K - - - sequence-specific DNA binding
HHIGLKPN_01963 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
HHIGLKPN_01964 3.21e-208 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HHIGLKPN_01965 1.46e-240 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HHIGLKPN_01966 2.82e-130 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HHIGLKPN_01967 3.27e-239 - - - S ko:K07133 - ko00000 cog cog1373
HHIGLKPN_01968 4.08e-47 - - - - - - - -
HHIGLKPN_01969 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HHIGLKPN_01970 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HHIGLKPN_01974 4.93e-214 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HHIGLKPN_01975 1.85e-83 - - - M - - - Rib/alpha-like repeat
HHIGLKPN_01976 5.49e-53 - - - - - - - -
HHIGLKPN_01977 2.11e-86 - - - - - - - -
HHIGLKPN_01978 0.0 pepC4 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HHIGLKPN_01979 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HHIGLKPN_01980 4.19e-197 - - - I - - - Alpha/beta hydrolase family
HHIGLKPN_01981 2.03e-250 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HHIGLKPN_01982 1.87e-58 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
HHIGLKPN_01983 2.18e-215 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
HHIGLKPN_01984 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
HHIGLKPN_01985 2.39e-115 - - - - - - - -
HHIGLKPN_01986 5.87e-99 M1-431 - - S - - - Protein of unknown function (DUF1706)
HHIGLKPN_01987 2.9e-63 ytwI - - S - - - Protein of unknown function (DUF441)
HHIGLKPN_01988 4.84e-23 - - - - - - - -
HHIGLKPN_01989 1.27e-168 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
HHIGLKPN_01990 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HHIGLKPN_01991 1.22e-121 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
HHIGLKPN_01992 1.64e-86 - - - S - - - Domain of unknown function DUF1828
HHIGLKPN_01993 3.15e-22 - - - - - - - -
HHIGLKPN_01994 2.78e-67 - - - - - - - -
HHIGLKPN_01995 1.67e-221 citR - - K - - - Putative sugar-binding domain
HHIGLKPN_01996 0.0 - - - S - - - Putative threonine/serine exporter
HHIGLKPN_01997 1.04e-125 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HHIGLKPN_01998 1.73e-122 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Beta-lactamase
HHIGLKPN_01999 8.85e-159 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HHIGLKPN_02000 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HHIGLKPN_02002 1.57e-150 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
HHIGLKPN_02003 6.91e-165 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
HHIGLKPN_02004 1.19e-195 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Quinolinate phosphoribosyl transferase, C-terminal domain
HHIGLKPN_02005 3.03e-277 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
HHIGLKPN_02006 2.76e-287 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
HHIGLKPN_02007 8.29e-63 repA - - S - - - Replication initiator protein A
HHIGLKPN_02008 3.53e-92 repA - - S - - - Replication initiator protein A
HHIGLKPN_02009 1.46e-84 - - - M - - - domain protein
HHIGLKPN_02010 3.49e-115 - - - M - - - YSIRK type signal peptide
HHIGLKPN_02011 9.08e-21 - - - M - - - domain protein
HHIGLKPN_02012 2.71e-180 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HHIGLKPN_02013 2.26e-15 - - - - - - - -
HHIGLKPN_02014 3.3e-196 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HHIGLKPN_02015 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HHIGLKPN_02016 1.64e-262 - - - M - - - Glycosyl transferases group 1
HHIGLKPN_02017 1.69e-172 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HHIGLKPN_02018 5.75e-209 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HHIGLKPN_02019 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
HHIGLKPN_02020 0.0 - - - E - - - Amino acid permease
HHIGLKPN_02021 3.25e-106 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HHIGLKPN_02022 2.04e-275 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HHIGLKPN_02023 5.42e-275 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
HHIGLKPN_02024 1.89e-276 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
HHIGLKPN_02025 1.9e-61 - - - - - - - -
HHIGLKPN_02026 7.53e-24 ybcH - - D ko:K06889 - ko00000 Alpha beta
HHIGLKPN_02027 7.72e-297 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHIGLKPN_02028 9.17e-172 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HHIGLKPN_02029 1.91e-151 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HHIGLKPN_02030 1.8e-202 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HHIGLKPN_02031 2.66e-57 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
HHIGLKPN_02034 1.41e-137 - - - S - - - Domain of unknown function (DUF4767)
HHIGLKPN_02035 9.13e-153 - - - S - - - Membrane
HHIGLKPN_02036 1.7e-55 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
HHIGLKPN_02037 6.76e-111 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HHIGLKPN_02038 1.02e-260 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HHIGLKPN_02039 4.19e-41 - - - M - - - Glycosyltransferase, group 1 family
HHIGLKPN_02040 1.1e-188 idhA 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHIGLKPN_02041 2e-99 - - - S ko:K07088 - ko00000 Membrane transport protein
HHIGLKPN_02042 1.63e-198 is18 - - L - - - Integrase core domain
HHIGLKPN_02043 1.44e-51 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
HHIGLKPN_02044 7.66e-97 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HHIGLKPN_02045 1.46e-170 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HHIGLKPN_02046 5.39e-292 - - - G - - - Antibiotic biosynthesis monooxygenase
HHIGLKPN_02047 3.24e-143 - - - G - - - Phosphoglycerate mutase family
HHIGLKPN_02048 3.94e-249 - - - D - - - nuclear chromosome segregation
HHIGLKPN_02049 1.25e-120 - - - M - - - LysM domain protein
HHIGLKPN_02050 5.26e-19 - - - - - - - -
HHIGLKPN_02051 5.1e-33 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
HHIGLKPN_02052 1.56e-121 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
HHIGLKPN_02053 4.63e-88 - - - - - - - -
HHIGLKPN_02054 1.52e-43 - - - - - - - -
HHIGLKPN_02055 4.09e-92 - - - S - - - Iron-sulphur cluster biosynthesis
HHIGLKPN_02056 8.08e-68 - - - K - - - Helix-turn-helix domain, rpiR family
HHIGLKPN_02057 9.96e-291 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HHIGLKPN_02058 1.96e-164 - - - K ko:K03710 - ko00000,ko03000 UTRA
HHIGLKPN_02060 1.63e-87 - - - C - - - FAD binding domain
HHIGLKPN_02061 5.84e-32 - - - C - - - FAD binding domain
HHIGLKPN_02062 5.65e-60 - - - C - - - FAD binding domain
HHIGLKPN_02063 2e-09 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
HHIGLKPN_02064 1.98e-179 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
HHIGLKPN_02065 4.75e-80 - - - - - - - -
HHIGLKPN_02066 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
HHIGLKPN_02067 0.0 - - - P - - - P-loop Domain of unknown function (DUF2791)
HHIGLKPN_02068 0.0 - - - S - - - TerB-C domain
HHIGLKPN_02069 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
HHIGLKPN_02070 7.52e-95 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
HHIGLKPN_02071 1.85e-48 - - - - - - - -
HHIGLKPN_02072 4.44e-170 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
HHIGLKPN_02073 6.43e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHIGLKPN_02074 3.7e-105 - - - S - - - LPXTG cell wall anchor motif
HHIGLKPN_02075 1.68e-117 - - - M - - - LPXTG-motif cell wall anchor domain protein
HHIGLKPN_02076 1.57e-94 - - - - - - - -
HHIGLKPN_02077 4.01e-134 - - - E - - - amino acid
HHIGLKPN_02078 7.04e-63 - - - - - - - -
HHIGLKPN_02079 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HHIGLKPN_02080 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HHIGLKPN_02081 8.91e-306 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HHIGLKPN_02082 3.09e-107 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HHIGLKPN_02083 4.77e-29 - - - K - - - Transcriptional regulator
HHIGLKPN_02084 2.22e-133 - - - K - - - Transcriptional regulator
HHIGLKPN_02085 2.76e-83 - - - S - - - Domain of unknown function (DUF956)
HHIGLKPN_02086 3.51e-222 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
HHIGLKPN_02087 5.16e-181 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
HHIGLKPN_02088 1.52e-238 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HHIGLKPN_02089 9.85e-78 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HHIGLKPN_02090 1.27e-214 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HHIGLKPN_02091 1.06e-49 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HHIGLKPN_02092 7.84e-109 scrA5 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HHIGLKPN_02093 4.58e-268 scrA5 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HHIGLKPN_02094 8.15e-164 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HHIGLKPN_02095 1.56e-125 - - - K - - - helix_turn_helix, arabinose operon control protein
HHIGLKPN_02096 3.7e-58 - - - K - - - helix_turn_helix, arabinose operon control protein
HHIGLKPN_02097 7.48e-59 metF 1.5.1.20 - C ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
HHIGLKPN_02098 6.26e-58 metF 1.5.1.20 - C ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
HHIGLKPN_02099 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HHIGLKPN_02100 2.49e-114 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HHIGLKPN_02101 5.51e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HHIGLKPN_02102 1.08e-155 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HHIGLKPN_02103 1.03e-210 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HHIGLKPN_02104 5.63e-120 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HHIGLKPN_02105 1.23e-85 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HHIGLKPN_02106 4.85e-100 - - - - - - - -
HHIGLKPN_02109 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HHIGLKPN_02110 2.31e-105 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HHIGLKPN_02111 7.28e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HHIGLKPN_02112 2.06e-157 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
HHIGLKPN_02113 6.31e-29 - - - - - - - -
HHIGLKPN_02114 1.14e-53 - - - S - - - Enterocin A Immunity
HHIGLKPN_02115 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHIGLKPN_02116 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HHIGLKPN_02117 6.36e-161 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
HHIGLKPN_02118 3.58e-161 gpm2 - - G - - - Phosphoglycerate mutase family
HHIGLKPN_02119 2.31e-59 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HHIGLKPN_02120 4.19e-175 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HHIGLKPN_02121 1.78e-79 - - - M - - - Glycosyltransferase like family 2
HHIGLKPN_02122 1.82e-83 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HHIGLKPN_02123 7.94e-220 yfdH - GT2 M ko:K12999,ko:K20534 - ko00000,ko01000,ko01003,ko01005,ko02000 Glycosyltransferase like family 2
HHIGLKPN_02124 8.41e-88 - - - S - - - GtrA-like protein
HHIGLKPN_02125 7.33e-272 - - - C - - - Glycerophosphoryl diester phosphodiesterase family
HHIGLKPN_02126 3.07e-32 - - - - - - - -
HHIGLKPN_02127 2.08e-167 - - - S - - - Adenine-specific methyltransferase EcoRI
HHIGLKPN_02128 4.22e-250 - - - V - - - Protein of unknown function DUF262
HHIGLKPN_02129 2.04e-50 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HHIGLKPN_02130 4.84e-34 - - - K - - - Probable zinc-ribbon domain
HHIGLKPN_02132 1.24e-219 - - - S ko:K07133 - ko00000 cog cog1373
HHIGLKPN_02133 5.85e-293 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HHIGLKPN_02134 3.03e-187 - - - S - - - haloacid dehalogenase-like hydrolase

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)