ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
LOFAKCML_00001 3.61e-154 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LOFAKCML_00002 5.75e-40 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LOFAKCML_00003 8.71e-157 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
LOFAKCML_00004 9.23e-81 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LOFAKCML_00005 3.64e-115 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LOFAKCML_00006 3.42e-73 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LOFAKCML_00007 1.78e-107 - 3.4.21.96 - S ko:K01361 - ko00000,ko01000,ko01002,ko03110 SLAP domain
LOFAKCML_00008 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
LOFAKCML_00009 9.46e-200 lysR5 - - K - - - LysR substrate binding domain
LOFAKCML_00010 7.37e-260 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
LOFAKCML_00011 7.26e-242 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LOFAKCML_00012 6.59e-210 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
LOFAKCML_00013 4.31e-123 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
LOFAKCML_00014 1.68e-275 - - - S - - - Sterol carrier protein domain
LOFAKCML_00015 6.5e-26 - - - - - - - -
LOFAKCML_00016 5.96e-135 - - - K - - - LysR substrate binding domain
LOFAKCML_00017 2.13e-77 - - - - - - - -
LOFAKCML_00018 1.55e-18 - - - - - - - -
LOFAKCML_00019 6.4e-131 - - - G - - - Antibiotic biosynthesis monooxygenase
LOFAKCML_00020 2.22e-157 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LOFAKCML_00021 2.15e-72 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LOFAKCML_00022 1.51e-306 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
LOFAKCML_00023 1.53e-156 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
LOFAKCML_00024 3.33e-30 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
LOFAKCML_00025 5.13e-05 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LOFAKCML_00026 1.59e-80 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LOFAKCML_00027 1.11e-50 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LOFAKCML_00028 3.94e-137 - - - - - - - -
LOFAKCML_00029 6.96e-206 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LOFAKCML_00030 2.53e-70 - - - S - - - Peptidase family M23
LOFAKCML_00031 3.16e-195 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LOFAKCML_00032 4.83e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
LOFAKCML_00033 1.21e-89 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
LOFAKCML_00034 2.03e-223 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
LOFAKCML_00035 1.99e-126 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LOFAKCML_00036 2.86e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LOFAKCML_00037 2.68e-173 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
LOFAKCML_00038 5.4e-227 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
LOFAKCML_00039 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
LOFAKCML_00040 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LOFAKCML_00041 7.08e-252 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LOFAKCML_00042 1.4e-159 - - - S - - - Peptidase family M23
LOFAKCML_00043 6.48e-89 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
LOFAKCML_00044 2.49e-158 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
LOFAKCML_00045 4.9e-197 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LOFAKCML_00046 4.94e-308 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
LOFAKCML_00047 7.06e-81 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
LOFAKCML_00048 1.81e-159 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LOFAKCML_00049 8.47e-181 - - - - - - - -
LOFAKCML_00050 1.36e-179 - - - - - - - -
LOFAKCML_00051 3.13e-173 - - - - - - - -
LOFAKCML_00052 0.0 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
LOFAKCML_00053 7.83e-38 - - - - - - - -
LOFAKCML_00054 2.67e-136 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LOFAKCML_00055 9.13e-182 - - - - - - - -
LOFAKCML_00056 3.38e-226 - - - - - - - -
LOFAKCML_00057 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
LOFAKCML_00058 2.7e-233 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LOFAKCML_00059 9.08e-259 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
LOFAKCML_00060 1.18e-227 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
LOFAKCML_00061 5.73e-210 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
LOFAKCML_00062 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
LOFAKCML_00063 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
LOFAKCML_00064 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
LOFAKCML_00065 6.04e-117 ypmB - - S - - - Protein conserved in bacteria
LOFAKCML_00066 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
LOFAKCML_00067 1.39e-148 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
LOFAKCML_00068 4.9e-145 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LOFAKCML_00069 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
LOFAKCML_00070 3.06e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LOFAKCML_00071 1.54e-135 ypsA - - S - - - Belongs to the UPF0398 family
LOFAKCML_00072 1.51e-90 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LOFAKCML_00073 2.79e-276 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
LOFAKCML_00074 1.07e-294 cpdA - - S - - - Calcineurin-like phosphoesterase
LOFAKCML_00075 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
LOFAKCML_00076 2.6e-101 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LOFAKCML_00077 2.52e-209 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LOFAKCML_00078 8.34e-255 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LOFAKCML_00079 0.0 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
LOFAKCML_00080 0.0 FbpA - - K - - - Fibronectin-binding protein
LOFAKCML_00081 2.32e-85 - - - - - - - -
LOFAKCML_00082 1.07e-205 - - - S - - - EDD domain protein, DegV family
LOFAKCML_00083 3.3e-261 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
LOFAKCML_00084 3.71e-95 - - - - - - - -
LOFAKCML_00085 2.73e-32 flaR - - F - - - topology modulation protein
LOFAKCML_00086 1.92e-140 XK27_00160 - - S - - - Domain of unknown function (DUF5052)
LOFAKCML_00087 8.5e-35 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
LOFAKCML_00088 1.73e-19 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
LOFAKCML_00089 1.13e-71 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
LOFAKCML_00090 2.15e-48 - - - S - - - Transglycosylase associated protein
LOFAKCML_00091 9.13e-59 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
LOFAKCML_00092 2.84e-33 - - - - - - - -
LOFAKCML_00093 1.14e-123 - - - - - - - -
LOFAKCML_00094 1.35e-135 - - - S - - - SLAP domain
LOFAKCML_00095 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LOFAKCML_00096 8.69e-192 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
LOFAKCML_00097 2.02e-52 veg - - S - - - Biofilm formation stimulator VEG
LOFAKCML_00098 9.89e-207 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LOFAKCML_00099 8.57e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LOFAKCML_00100 5.48e-189 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
LOFAKCML_00101 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LOFAKCML_00102 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
LOFAKCML_00103 2.26e-138 - - - S ko:K06872 - ko00000 TPM domain
LOFAKCML_00104 5.22e-117 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
LOFAKCML_00105 2.86e-245 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LOFAKCML_00106 1.79e-148 - - - E - - - Belongs to the SOS response-associated peptidase family
LOFAKCML_00108 8.62e-146 - - - - - - - -
LOFAKCML_00109 5.69e-100 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LOFAKCML_00110 2.05e-94 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LOFAKCML_00111 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
LOFAKCML_00112 2.66e-221 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LOFAKCML_00113 3.02e-253 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LOFAKCML_00114 1.07e-237 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOFAKCML_00115 6.08e-188 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOFAKCML_00116 1.21e-264 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LOFAKCML_00117 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LOFAKCML_00118 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LOFAKCML_00119 7.92e-151 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
LOFAKCML_00120 0.0 pepC1 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
LOFAKCML_00122 3.32e-37 - - - - - - - -
LOFAKCML_00123 6.27e-24 - - - - - - - -
LOFAKCML_00124 1.04e-308 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LOFAKCML_00125 0.0 - - - S - - - Fibronectin type III domain
LOFAKCML_00126 0.0 XK27_08315 - - M - - - Sulfatase
LOFAKCML_00127 2.52e-142 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LOFAKCML_00128 8.94e-252 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LOFAKCML_00129 3.8e-130 - - - G - - - Aldose 1-epimerase
LOFAKCML_00130 2.01e-141 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LOFAKCML_00131 4.51e-171 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LOFAKCML_00132 1.6e-170 - - - - - - - -
LOFAKCML_00133 4.67e-163 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
LOFAKCML_00134 2.23e-150 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
LOFAKCML_00135 3.51e-292 - - - L - - - COG3547 Transposase and inactivated derivatives
LOFAKCML_00136 2.34e-49 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
LOFAKCML_00137 8.96e-122 - - - - - - - -
LOFAKCML_00138 8.14e-61 - - - - - - - -
LOFAKCML_00139 3.51e-99 - - - - - - - -
LOFAKCML_00140 3.62e-126 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
LOFAKCML_00142 9.02e-33 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
LOFAKCML_00143 4.53e-295 B4168_4126 - - L ko:K07493 - ko00000 Transposase
LOFAKCML_00144 4.62e-251 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
LOFAKCML_00145 4.56e-120 - - - - - - - -
LOFAKCML_00146 3.9e-79 - - - S ko:K09707 - ko00000 ACT domain
LOFAKCML_00147 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LOFAKCML_00148 1.79e-213 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
LOFAKCML_00149 1.24e-314 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
LOFAKCML_00150 5.46e-108 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LOFAKCML_00151 1.03e-134 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LOFAKCML_00152 3.73e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LOFAKCML_00153 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LOFAKCML_00154 2.56e-19 - - - - - - - -
LOFAKCML_00155 2.86e-39 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LOFAKCML_00156 3.52e-252 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LOFAKCML_00157 5.94e-161 cas4 3.1.12.1 - L ko:K07464 - ko00000,ko01000,ko02048 Domain of unknown function DUF83
LOFAKCML_00158 5.5e-203 csd2 - - L ko:K19115,ko:K19118 - ko00000,ko02048 CRISPR-associated protein Cas7
LOFAKCML_00159 0.0 csd1 - - M ko:K19117 - ko00000,ko02048 CRISPR-associated protein (Cas_Csd1)
LOFAKCML_00160 1.11e-184 cas5 - - S ko:K19119 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas5)
LOFAKCML_00161 0.0 - - - L ko:K07012 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
LOFAKCML_00162 1.86e-306 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
LOFAKCML_00163 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
LOFAKCML_00164 1.03e-133 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LOFAKCML_00165 9.33e-248 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
LOFAKCML_00166 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LOFAKCML_00167 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LOFAKCML_00168 2.51e-160 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LOFAKCML_00169 4.44e-51 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LOFAKCML_00170 1.19e-170 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
LOFAKCML_00171 1.1e-275 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LOFAKCML_00172 3.23e-103 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LOFAKCML_00173 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
LOFAKCML_00174 3.72e-159 - - - C - - - Flavodoxin
LOFAKCML_00175 3.15e-46 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
LOFAKCML_00176 6.91e-129 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
LOFAKCML_00177 1.11e-31 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
LOFAKCML_00178 3.05e-21 - - - - - - - -
LOFAKCML_00179 4.58e-248 - - - S - - - Bacteriocin helveticin-J
LOFAKCML_00180 0.0 - - - M - - - Peptidase family M1 domain
LOFAKCML_00181 9.67e-225 - - - S - - - SLAP domain
LOFAKCML_00182 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
LOFAKCML_00183 1.16e-205 - - - L - - - An automated process has identified a potential problem with this gene model
LOFAKCML_00194 3.47e-183 - - - S - - - Peptidase_C39 like family
LOFAKCML_00196 7.86e-33 - - - - - - - -
LOFAKCML_00197 6.43e-142 - - - L - - - Probable transposase
LOFAKCML_00199 1.97e-71 - 3.2.1.4 GH5,GH9 M ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 domain protein
LOFAKCML_00200 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LOFAKCML_00201 1.82e-144 - - - S - - - repeat protein
LOFAKCML_00202 4.34e-159 pgm - - G - - - Phosphoglycerate mutase family
LOFAKCML_00203 1.34e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LOFAKCML_00204 2.01e-74 XK27_04120 - - S - - - Putative amino acid metabolism
LOFAKCML_00205 1.28e-273 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
LOFAKCML_00206 1.69e-162 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LOFAKCML_00207 2.13e-55 - - - - - - - -
LOFAKCML_00208 3.64e-134 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
LOFAKCML_00209 1.15e-43 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
LOFAKCML_00210 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LOFAKCML_00211 1.44e-164 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
LOFAKCML_00212 1.1e-189 ylmH - - S - - - S4 domain protein
LOFAKCML_00213 5.07e-62 yggT - - S ko:K02221 - ko00000,ko02044 YGGT family
LOFAKCML_00214 1.04e-94 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LOFAKCML_00215 5.53e-262 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LOFAKCML_00216 4.95e-305 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LOFAKCML_00217 2.83e-181 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LOFAKCML_00218 2.44e-267 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LOFAKCML_00219 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LOFAKCML_00220 5.4e-225 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LOFAKCML_00221 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LOFAKCML_00222 2.2e-70 ftsL - - D - - - Cell division protein FtsL
LOFAKCML_00223 3.29e-232 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LOFAKCML_00224 8.99e-99 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
LOFAKCML_00225 6.2e-53 - - - L - - - PFAM transposase, IS4 family protein
LOFAKCML_00226 8.66e-70 - - - S - - - Protein of unknown function (DUF3397)
LOFAKCML_00227 1.09e-18 - - - S - - - Protein of unknown function (DUF4044)
LOFAKCML_00228 1.97e-124 mreD - - - ko:K03571 - ko00000,ko03036 -
LOFAKCML_00229 8.27e-189 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
LOFAKCML_00230 8.26e-226 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
LOFAKCML_00231 3.32e-148 radC - - L ko:K03630 - ko00000 DNA repair protein
LOFAKCML_00232 4.33e-162 - - - S - - - Haloacid dehalogenase-like hydrolase
LOFAKCML_00233 1.25e-302 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
LOFAKCML_00234 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LOFAKCML_00235 1.19e-130 - - - - ko:K19167 - ko00000,ko02048 -
LOFAKCML_00236 2.38e-115 - - - S - - - Bacterial membrane protein, YfhO
LOFAKCML_00237 1.21e-106 - - - S - - - Bacterial membrane protein, YfhO
LOFAKCML_00238 4.99e-71 - - - S - - - Bacterial membrane protein, YfhO
LOFAKCML_00239 1.47e-215 yfdH - GT2 M ko:K12999,ko:K20534 - ko00000,ko01000,ko01003,ko01005,ko02000 Glycosyltransferase like family 2
LOFAKCML_00240 1.2e-87 - - - S - - - GtrA-like protein
LOFAKCML_00241 2.75e-267 - - - C - - - Glycerophosphoryl diester phosphodiesterase family
LOFAKCML_00242 1.32e-11 - - - - - - - -
LOFAKCML_00243 4.48e-60 - - - S - - - Uncharacterised protein family (UPF0236)
LOFAKCML_00244 1.43e-68 - - - L - - - An automated process has identified a potential problem with this gene model
LOFAKCML_00245 2.66e-57 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
LOFAKCML_00246 1.42e-57 - - - - - - - -
LOFAKCML_00247 1.27e-99 - - - K - - - LytTr DNA-binding domain
LOFAKCML_00248 3.06e-85 - - - S - - - Protein of unknown function (DUF3021)
LOFAKCML_00249 2.76e-115 - - - K - - - Acetyltransferase (GNAT) domain
LOFAKCML_00250 2.36e-188 - - - - - - - -
LOFAKCML_00251 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LOFAKCML_00252 6.09e-240 flp - - V - - - Beta-lactamase
LOFAKCML_00253 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
LOFAKCML_00254 1.59e-74 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
LOFAKCML_00255 6.8e-130 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
LOFAKCML_00256 2.75e-09 - - - - - - - -
LOFAKCML_00257 9.25e-123 tdh 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
LOFAKCML_00258 1.53e-162 - - - S - - - KR domain
LOFAKCML_00259 2.17e-138 - - - C - - - nitroreductase
LOFAKCML_00260 7.47e-82 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
LOFAKCML_00261 3.8e-91 - - - GK - - - ROK family
LOFAKCML_00263 4.59e-79 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
LOFAKCML_00264 7.31e-75 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
LOFAKCML_00265 7.23e-22 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
LOFAKCML_00266 6.12e-118 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
LOFAKCML_00267 3.72e-308 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LOFAKCML_00268 3.2e-72 - - - - - - - -
LOFAKCML_00269 8.26e-82 - - - S - - - SLAP domain
LOFAKCML_00270 2.18e-236 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
LOFAKCML_00271 8.9e-51 - - - - - - - -
LOFAKCML_00272 5.43e-133 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
LOFAKCML_00273 4.99e-10 - - - - - - - -
LOFAKCML_00274 5.45e-121 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
LOFAKCML_00275 2.85e-58 - - - S - - - C4-dicarboxylate anaerobic carrier
LOFAKCML_00276 1.74e-36 - - - S - - - C4-dicarboxylate anaerobic carrier
LOFAKCML_00277 9.58e-64 - - - S - - - C4-dicarboxylate anaerobic carrier
LOFAKCML_00278 1.96e-42 - - - S - - - C4-dicarboxylate anaerobic carrier
LOFAKCML_00279 7.87e-257 - - - - - - - -
LOFAKCML_00280 3.47e-264 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
LOFAKCML_00281 3.9e-306 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
LOFAKCML_00282 5.94e-42 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LOFAKCML_00283 3.24e-101 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LOFAKCML_00284 2.03e-80 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
LOFAKCML_00285 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
LOFAKCML_00286 6.71e-35 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LOFAKCML_00287 2.33e-63 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LOFAKCML_00288 3.01e-72 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LOFAKCML_00289 0.0 XK27_11280 - - S - - - Psort location CytoplasmicMembrane, score
LOFAKCML_00290 3.86e-27 - - - K - - - DNA-binding transcription factor activity
LOFAKCML_00291 2.19e-77 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
LOFAKCML_00292 1.24e-277 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LOFAKCML_00294 4.34e-281 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LOFAKCML_00295 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LOFAKCML_00296 4.28e-312 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
LOFAKCML_00297 1.43e-96 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LOFAKCML_00298 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LOFAKCML_00299 4.44e-79 - - - - - - - -
LOFAKCML_00300 7.07e-222 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
LOFAKCML_00301 1.52e-114 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LOFAKCML_00303 3.91e-26 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LOFAKCML_00305 3.71e-34 - - - - ko:K14201 ko05150,map05150 ko00000,ko00001 -
LOFAKCML_00306 1.42e-123 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
LOFAKCML_00307 1.38e-309 - - - S - - - Putative threonine/serine exporter
LOFAKCML_00308 2.82e-214 citR - - K - - - Putative sugar-binding domain
LOFAKCML_00309 2.48e-69 - - - - - - - -
LOFAKCML_00310 2.72e-85 - - - S - - - Domain of unknown function DUF1828
LOFAKCML_00311 1.8e-123 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
LOFAKCML_00312 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LOFAKCML_00313 4.46e-190 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
LOFAKCML_00314 1.01e-24 - - - - - - - -
LOFAKCML_00315 1.45e-92 ytwI - - S - - - Protein of unknown function (DUF441)
LOFAKCML_00316 2.15e-280 B4168_4126 - - L ko:K07493 - ko00000 Transposase
LOFAKCML_00317 2.91e-99 M1-431 - - S - - - Protein of unknown function (DUF1706)
LOFAKCML_00318 3.55e-149 - - - - - - - -
LOFAKCML_00319 2.08e-11 - - - - - - - -
LOFAKCML_00320 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
LOFAKCML_00321 5.13e-214 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
LOFAKCML_00322 2.27e-59 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
LOFAKCML_00323 2.65e-246 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
LOFAKCML_00324 4.19e-197 - - - I - - - Alpha/beta hydrolase family
LOFAKCML_00325 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
LOFAKCML_00326 0.0 pepC4 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
LOFAKCML_00327 1.62e-63 - - - - - - - -
LOFAKCML_00328 2.2e-68 - - - - - - - -
LOFAKCML_00332 4.69e-71 - - - S - - - Protein of unknown function (DUF1275)
LOFAKCML_00333 6.39e-73 - - - K - - - Helix-turn-helix domain
LOFAKCML_00334 5.37e-143 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LOFAKCML_00335 3.5e-220 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
LOFAKCML_00336 1.42e-217 - - - K - - - Transcriptional regulator
LOFAKCML_00337 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LOFAKCML_00338 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LOFAKCML_00339 8.01e-134 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LOFAKCML_00340 0.0 snf - - KL - - - domain protein
LOFAKCML_00341 3.06e-51 - - - - - - - -
LOFAKCML_00342 9.82e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
LOFAKCML_00343 1.07e-120 - - - K - - - acetyltransferase
LOFAKCML_00344 1.66e-210 - - - K - - - COG COG0846 NAD-dependent protein deacetylases, SIR2 family
LOFAKCML_00345 5.4e-121 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LOFAKCML_00346 2.85e-133 - - - K ko:K09705 - ko00000 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LOFAKCML_00347 2.02e-09 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
LOFAKCML_00348 5.21e-41 - 1.1.1.3 - T ko:K00003,ko:K07166 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 phosphoserine phosphatase activity
LOFAKCML_00349 5.69e-185 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
LOFAKCML_00350 3.33e-49 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
LOFAKCML_00351 1.71e-26 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
LOFAKCML_00352 3.5e-77 - - - S - - - Alpha beta hydrolase
LOFAKCML_00353 4.35e-120 - - - K - - - Acetyltransferase (GNAT) family
LOFAKCML_00354 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
LOFAKCML_00356 3.89e-151 - - - L - - - Integrase
LOFAKCML_00358 2.83e-115 dpnM 2.1.1.72 - H ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 Site-specific DNA-methyltransferase (adenine-specific)
LOFAKCML_00359 1.67e-250 - - - L ko:K07497 - ko00000 hmm pf00665
LOFAKCML_00360 4.41e-78 - - - L - - - Helix-turn-helix domain
LOFAKCML_00361 7.24e-205 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
LOFAKCML_00362 1.39e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LOFAKCML_00363 1.97e-121 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
LOFAKCML_00364 1.55e-143 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
LOFAKCML_00365 2.44e-90 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
LOFAKCML_00366 2.03e-34 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
LOFAKCML_00367 2.54e-63 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
LOFAKCML_00368 1.57e-68 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 N-formylglutamate amidohydrolase
LOFAKCML_00369 3.16e-125 - 3.6.1.67 - F ko:K19965 ko00790,map00790 ko00000,ko00001,ko00002,ko01000 NUDIX domain
LOFAKCML_00370 5.84e-255 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
LOFAKCML_00371 9.34e-317 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
LOFAKCML_00372 1.24e-259 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
LOFAKCML_00373 8.76e-75 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LOFAKCML_00374 4.52e-160 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
LOFAKCML_00375 1.68e-229 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
LOFAKCML_00376 4.79e-274 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
LOFAKCML_00377 2.07e-65 - - - - - - - -
LOFAKCML_00378 3.11e-28 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LOFAKCML_00379 1.05e-191 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
LOFAKCML_00380 3.59e-147 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LOFAKCML_00381 3.98e-188 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
LOFAKCML_00382 3.63e-91 yslB - - S - - - Protein of unknown function (DUF2507)
LOFAKCML_00383 5.38e-63 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LOFAKCML_00384 2.19e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LOFAKCML_00385 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LOFAKCML_00386 1.18e-66 yrzB - - S - - - Belongs to the UPF0473 family
LOFAKCML_00387 2.69e-95 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LOFAKCML_00388 5.32e-57 yrzL - - S - - - Belongs to the UPF0297 family
LOFAKCML_00389 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LOFAKCML_00390 3.15e-67 - - - - - - - -
LOFAKCML_00391 1.05e-82 - - - - - - - -
LOFAKCML_00392 5.24e-312 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LOFAKCML_00393 1.56e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
LOFAKCML_00394 9.26e-270 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LOFAKCML_00395 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LOFAKCML_00396 1.42e-76 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
LOFAKCML_00397 4.17e-237 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LOFAKCML_00398 1.47e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LOFAKCML_00399 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LOFAKCML_00400 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LOFAKCML_00401 5.78e-63 - - - - - - - -
LOFAKCML_00402 4.31e-194 levD - - G ko:K02771 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
LOFAKCML_00403 3.44e-184 levC - - M ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
LOFAKCML_00404 2.98e-120 levB 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
LOFAKCML_00405 1.21e-89 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
LOFAKCML_00406 5.56e-135 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein domain
LOFAKCML_00407 3.91e-253 degS 2.7.13.3 - F ko:K07683,ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
LOFAKCML_00408 4.17e-136 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
LOFAKCML_00409 2.68e-238 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
LOFAKCML_00410 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LOFAKCML_00411 9.06e-60 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LOFAKCML_00412 1.08e-139 - - - L - - - Belongs to the 'phage' integrase family
LOFAKCML_00413 5.04e-71 - - - - - - - -
LOFAKCML_00414 1.28e-131 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
LOFAKCML_00415 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LOFAKCML_00416 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LOFAKCML_00417 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LOFAKCML_00418 7.88e-97 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LOFAKCML_00419 1.76e-178 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LOFAKCML_00420 4.1e-118 comX - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
LOFAKCML_00421 2.41e-45 - - - - - - - -
LOFAKCML_00422 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
LOFAKCML_00423 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LOFAKCML_00424 8.53e-34 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LOFAKCML_00425 5e-130 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
LOFAKCML_00426 3.82e-90 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LOFAKCML_00427 3.02e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LOFAKCML_00428 1.1e-200 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
LOFAKCML_00429 1.65e-219 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
LOFAKCML_00430 1.82e-198 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
LOFAKCML_00431 1.38e-182 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LOFAKCML_00432 3.28e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LOFAKCML_00433 1.43e-151 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
LOFAKCML_00434 5.28e-33 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
LOFAKCML_00435 2.66e-29 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
LOFAKCML_00436 4.39e-151 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
LOFAKCML_00437 6.16e-110 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LOFAKCML_00438 2.28e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LOFAKCML_00439 2.3e-36 - 2.1.1.172 - J ko:K00564,ko:K10716 - ko00000,ko01000,ko02000,ko03009 Ion channel
LOFAKCML_00440 1.36e-121 - 2.1.1.172 - J ko:K00564,ko:K10716 - ko00000,ko01000,ko02000,ko03009 Ion channel
LOFAKCML_00441 1.02e-143 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
LOFAKCML_00442 1.53e-118 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LOFAKCML_00443 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LOFAKCML_00444 3.64e-58 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LOFAKCML_00445 5.33e-141 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LOFAKCML_00446 1.13e-44 - - - S - - - Protein of unknown function (DUF2508)
LOFAKCML_00447 4.67e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LOFAKCML_00448 6.21e-68 yaaQ - - S - - - Cyclic-di-AMP receptor
LOFAKCML_00449 1.9e-195 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LOFAKCML_00450 2.32e-79 yabA - - L - - - Involved in initiation control of chromosome replication
LOFAKCML_00451 8.76e-197 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LOFAKCML_00452 6.78e-164 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
LOFAKCML_00453 1.51e-111 - - - S - - - ECF transporter, substrate-specific component
LOFAKCML_00454 1.33e-170 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
LOFAKCML_00455 6.27e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
LOFAKCML_00456 4.95e-246 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LOFAKCML_00457 1.09e-161 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LOFAKCML_00458 3.83e-230 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
LOFAKCML_00459 5.83e-161 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
LOFAKCML_00460 3.73e-22 - - - S - - - Toxin ToxN, type III toxin-antitoxin system
LOFAKCML_00461 3.04e-180 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
LOFAKCML_00462 5.12e-302 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
LOFAKCML_00463 5.44e-116 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LOFAKCML_00464 0.0 qacA - - EGP - - - Major Facilitator
LOFAKCML_00465 2.3e-275 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
LOFAKCML_00466 7.25e-265 pepA - - E - - - M42 glutamyl aminopeptidase
LOFAKCML_00467 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
LOFAKCML_00468 3.97e-40 - - - - - - - -
LOFAKCML_00469 1.87e-116 - - - - - - - -
LOFAKCML_00470 7.51e-166 - - - F - - - glutamine amidotransferase
LOFAKCML_00471 1.23e-189 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LOFAKCML_00472 1.47e-103 - - - K - - - Transcriptional regulator, MarR family
LOFAKCML_00473 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LOFAKCML_00474 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
LOFAKCML_00475 1.47e-130 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
LOFAKCML_00476 2.1e-219 - - - EGP - - - Major facilitator superfamily
LOFAKCML_00477 4.85e-145 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
LOFAKCML_00478 2.61e-110 - - - L ko:K07491 - ko00000 Transposase IS200 like
LOFAKCML_00479 8.33e-282 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
LOFAKCML_00480 2.3e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LOFAKCML_00481 1.5e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LOFAKCML_00482 3.14e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LOFAKCML_00483 8.23e-138 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LOFAKCML_00484 3.68e-190 - - - S - - - Protein of unknown function (DUF2974)
LOFAKCML_00485 1.17e-146 - - - S - - - SLAP domain
LOFAKCML_00486 3.92e-306 srrA1 - - G ko:K02027,ko:K17244 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LOFAKCML_00487 5.13e-209 - - - C - - - Domain of unknown function (DUF4931)
LOFAKCML_00488 4.52e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LOFAKCML_00489 3.83e-163 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LOFAKCML_00490 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
LOFAKCML_00491 2.03e-222 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
LOFAKCML_00492 7.43e-171 gntR - - K - - - UbiC transcription regulator-associated domain protein
LOFAKCML_00493 5.69e-195 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
LOFAKCML_00494 1.38e-225 degV1 - - S - - - DegV family
LOFAKCML_00495 6.65e-208 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
LOFAKCML_00496 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
LOFAKCML_00497 3.87e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
LOFAKCML_00498 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
LOFAKCML_00499 4.36e-41 - - - S - - - SLAP domain
LOFAKCML_00500 1.89e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LOFAKCML_00501 1.76e-110 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LOFAKCML_00502 1.93e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
LOFAKCML_00503 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LOFAKCML_00504 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LOFAKCML_00505 2.09e-267 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LOFAKCML_00506 4.08e-47 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
LOFAKCML_00507 5.01e-255 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LOFAKCML_00508 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LOFAKCML_00509 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
LOFAKCML_00510 1.31e-81 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LOFAKCML_00511 2.17e-188 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LOFAKCML_00512 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LOFAKCML_00513 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LOFAKCML_00514 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LOFAKCML_00515 0.0 eriC - - P ko:K03281 - ko00000 chloride
LOFAKCML_00516 1.25e-264 - - - - - - - -
LOFAKCML_00517 6.46e-27 - - - - - - - -
LOFAKCML_00518 8.89e-217 - - - L - - - Bifunctional protein
LOFAKCML_00519 9.03e-297 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
LOFAKCML_00520 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
LOFAKCML_00521 2.57e-64 - - - S - - - Cupredoxin-like domain
LOFAKCML_00522 4.19e-84 - - - S - - - Cupredoxin-like domain
LOFAKCML_00523 2.02e-101 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
LOFAKCML_00524 1.18e-46 - - - - - - - -
LOFAKCML_00525 6.04e-290 pbuG - - S ko:K06901 - ko00000,ko02000 permease
LOFAKCML_00526 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LOFAKCML_00527 1.18e-184 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
LOFAKCML_00528 1.05e-112 - - - - - - - -
LOFAKCML_00529 2.6e-96 - - - - - - - -
LOFAKCML_00530 4.02e-204 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
LOFAKCML_00531 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LOFAKCML_00532 4.88e-59 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
LOFAKCML_00533 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
LOFAKCML_00534 3.55e-39 - - - - - - - -
LOFAKCML_00535 1.29e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
LOFAKCML_00536 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LOFAKCML_00537 1.08e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LOFAKCML_00538 2.5e-176 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LOFAKCML_00539 1.08e-203 coiA - - S ko:K06198 - ko00000 Competence protein
LOFAKCML_00540 5.3e-144 yjbH - - Q - - - Thioredoxin
LOFAKCML_00541 6.91e-139 - - - S - - - CYTH
LOFAKCML_00542 1.63e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
LOFAKCML_00543 2.52e-197 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LOFAKCML_00544 7.9e-215 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LOFAKCML_00545 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
LOFAKCML_00546 2.05e-88 - - - S - - - SNARE associated Golgi protein
LOFAKCML_00547 4.12e-255 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
LOFAKCML_00548 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
LOFAKCML_00549 3.3e-86 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
LOFAKCML_00550 8.55e-270 XK27_05220 - - S - - - AI-2E family transporter
LOFAKCML_00551 2.12e-136 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LOFAKCML_00552 4.46e-90 WQ51_03320 - - S - - - Protein of unknown function (DUF1149)
LOFAKCML_00553 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LOFAKCML_00554 4.05e-289 ymfF - - S - - - Peptidase M16 inactive domain protein
LOFAKCML_00555 1.85e-301 ymfH - - S - - - Peptidase M16
LOFAKCML_00556 1.55e-168 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
LOFAKCML_00557 1.33e-186 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
LOFAKCML_00558 3e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LOFAKCML_00559 8.51e-246 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LOFAKCML_00560 1.66e-283 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
LOFAKCML_00561 3.59e-264 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
LOFAKCML_00562 1.14e-150 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
LOFAKCML_00563 5e-311 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
LOFAKCML_00564 1.63e-169 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
LOFAKCML_00565 6.59e-124 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LOFAKCML_00566 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LOFAKCML_00567 3.57e-237 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LOFAKCML_00568 5.54e-51 - - - - - - - -
LOFAKCML_00569 2.39e-228 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LOFAKCML_00570 7.49e-199 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LOFAKCML_00571 3.46e-241 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
LOFAKCML_00572 2.66e-09 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LOFAKCML_00573 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LOFAKCML_00574 8.53e-208 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LOFAKCML_00575 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
LOFAKCML_00576 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LOFAKCML_00577 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LOFAKCML_00578 7.57e-109 - - - S - - - Short repeat of unknown function (DUF308)
LOFAKCML_00579 1.6e-287 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LOFAKCML_00580 0.0 - - - E - - - amino acid
LOFAKCML_00581 6.65e-196 yhaX - - S - - - Sucrose-6F-phosphate phosphohydrolase
LOFAKCML_00582 5.28e-53 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
LOFAKCML_00583 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LOFAKCML_00584 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LOFAKCML_00585 1.33e-79 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LOFAKCML_00586 7.68e-275 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LOFAKCML_00587 5.52e-120 - - - K - - - transcriptional regulator
LOFAKCML_00588 8.34e-165 - - - S - - - (CBS) domain
LOFAKCML_00589 3.42e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LOFAKCML_00590 1.89e-134 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LOFAKCML_00591 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LOFAKCML_00592 1.26e-46 yabO - - J - - - S4 domain protein
LOFAKCML_00593 6.18e-77 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
LOFAKCML_00594 3.8e-80 - - - J ko:K07571 - ko00000 S1 RNA binding domain
LOFAKCML_00595 1.34e-304 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LOFAKCML_00596 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LOFAKCML_00597 5.97e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LOFAKCML_00598 5.82e-250 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LOFAKCML_00599 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
LOFAKCML_00602 7.84e-106 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
LOFAKCML_00603 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LOFAKCML_00604 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LOFAKCML_00605 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LOFAKCML_00606 1.09e-66 - - - M - - - Lysin motif
LOFAKCML_00607 1.81e-149 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
LOFAKCML_00608 8.97e-274 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
LOFAKCML_00609 3.67e-312 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
LOFAKCML_00610 1.17e-56 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LOFAKCML_00611 5.61e-292 XK27_05225 - - S - - - Tetratricopeptide repeat protein
LOFAKCML_00612 7.21e-205 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LOFAKCML_00613 1.26e-287 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LOFAKCML_00614 5.77e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
LOFAKCML_00615 6.79e-190 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
LOFAKCML_00616 9.85e-49 yozE - - S - - - Belongs to the UPF0346 family
LOFAKCML_00617 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
LOFAKCML_00618 1.84e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LOFAKCML_00619 3.02e-171 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LOFAKCML_00620 5.47e-198 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
LOFAKCML_00621 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LOFAKCML_00622 1.42e-315 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LOFAKCML_00623 3.92e-217 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
LOFAKCML_00624 1.15e-116 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LOFAKCML_00625 3.41e-299 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LOFAKCML_00626 7.1e-223 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
LOFAKCML_00627 5e-32 - - - - - - - -
LOFAKCML_00628 1.35e-39 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
LOFAKCML_00629 4.34e-71 - - - L - - - Transposase and inactivated derivatives
LOFAKCML_00630 6.6e-28 - - - L ko:K07484 - ko00000 Transposase IS66 family
LOFAKCML_00631 3.16e-36 - - - L - - - Transposase and inactivated derivatives
LOFAKCML_00632 5.91e-37 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LOFAKCML_00633 5.97e-13 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LOFAKCML_00634 1.06e-194 - - - L - - - Phage integrase, N-terminal SAM-like domain
LOFAKCML_00635 4.86e-84 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LOFAKCML_00636 2.08e-84 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LOFAKCML_00637 4.62e-37 - - - C - - - Pyridoxamine 5'-phosphate oxidase
LOFAKCML_00638 1.66e-59 - - - C - - - Pyridoxamine 5'-phosphate oxidase
LOFAKCML_00639 0.0 - - - E - - - Amino acid permease
LOFAKCML_00640 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
LOFAKCML_00641 6.31e-314 ynbB - - P - - - aluminum resistance
LOFAKCML_00642 8.62e-75 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
LOFAKCML_00643 1.43e-47 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
LOFAKCML_00644 1.59e-86 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
LOFAKCML_00645 2.13e-186 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
LOFAKCML_00646 4.53e-301 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
LOFAKCML_00647 6.39e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LOFAKCML_00648 1.07e-104 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
LOFAKCML_00649 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
LOFAKCML_00650 1.51e-73 yitW - - S - - - Iron-sulfur cluster assembly protein
LOFAKCML_00651 5.69e-74 - - - S - - - Enterocin A Immunity
LOFAKCML_00652 1.86e-172 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
LOFAKCML_00653 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
LOFAKCML_00654 1.59e-206 - - - S - - - Phospholipase, patatin family
LOFAKCML_00655 2.65e-18 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
LOFAKCML_00656 2.23e-110 - - - S - - - hydrolase
LOFAKCML_00657 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
LOFAKCML_00658 3.43e-184 glvR - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
LOFAKCML_00659 1.06e-94 - - - - - - - -
LOFAKCML_00660 9.32e-112 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LOFAKCML_00661 2.89e-52 - - - - - - - -
LOFAKCML_00662 2.85e-23 - - - C - - - nitroreductase
LOFAKCML_00663 1.57e-35 - - - C - - - nitroreductase
LOFAKCML_00664 1.29e-312 yhdP - - S - - - Transporter associated domain
LOFAKCML_00665 2.46e-132 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
LOFAKCML_00666 2.75e-287 - - - E ko:K03294 - ko00000 amino acid
LOFAKCML_00667 6.35e-164 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
LOFAKCML_00668 5.51e-267 yfmL - - L - - - DEAD DEAH box helicase
LOFAKCML_00669 1.5e-310 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LOFAKCML_00671 5.82e-35 - - - - - - - -
LOFAKCML_00672 3.14e-276 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LOFAKCML_00673 5.01e-118 gtcA1 - - S - - - Teichoic acid glycosylation protein
LOFAKCML_00674 5.77e-102 ykuP - - C ko:K03839 - ko00000 Flavodoxin
LOFAKCML_00675 4.23e-212 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
LOFAKCML_00676 3.93e-199 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
LOFAKCML_00677 1.72e-214 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LOFAKCML_00678 5.86e-275 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
LOFAKCML_00679 1.27e-273 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
LOFAKCML_00680 7.39e-274 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
LOFAKCML_00681 1.62e-62 - - - - - - - -
LOFAKCML_00682 2.57e-25 ybcH - - D ko:K06889 - ko00000 Alpha beta
LOFAKCML_00683 0.0 ycaM - - E - - - amino acid
LOFAKCML_00684 1.22e-122 - - - - - - - -
LOFAKCML_00685 1.73e-96 - - - - - - - -
LOFAKCML_00687 2.73e-240 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
LOFAKCML_00688 1.16e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LOFAKCML_00689 6.01e-288 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
LOFAKCML_00690 2.71e-183 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LOFAKCML_00691 3.58e-124 - - - - - - - -
LOFAKCML_00692 1.15e-200 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
LOFAKCML_00693 7.79e-173 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LOFAKCML_00694 5.23e-231 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
LOFAKCML_00695 2.18e-117 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
LOFAKCML_00696 7.47e-128 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LOFAKCML_00697 1.71e-209 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
LOFAKCML_00698 9.1e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LOFAKCML_00699 5.95e-176 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LOFAKCML_00700 3.09e-178 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LOFAKCML_00701 3.71e-261 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LOFAKCML_00702 5.87e-192 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LOFAKCML_00703 1.02e-215 ybbR - - S - - - YbbR-like protein
LOFAKCML_00704 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LOFAKCML_00705 5.9e-192 - - - S - - - hydrolase
LOFAKCML_00706 1.56e-187 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
LOFAKCML_00707 3.74e-153 - - - - - - - -
LOFAKCML_00708 2.06e-112 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LOFAKCML_00709 3.38e-273 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
LOFAKCML_00710 2.01e-185 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
LOFAKCML_00711 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LOFAKCML_00712 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LOFAKCML_00713 8.42e-236 ybcH - - D ko:K06889 - ko00000 Alpha beta
LOFAKCML_00714 8.45e-92 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
LOFAKCML_00715 2.55e-246 pbpX1 - - V - - - Beta-lactamase
LOFAKCML_00716 0.0 - - - L - - - Helicase C-terminal domain protein
LOFAKCML_00717 1.01e-260 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
LOFAKCML_00718 1.14e-42 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
LOFAKCML_00719 1.25e-204 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
LOFAKCML_00720 1.53e-212 - - - G - - - Phosphotransferase enzyme family
LOFAKCML_00721 6.49e-245 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LOFAKCML_00722 5.85e-38 - - - - - - - -
LOFAKCML_00723 2.03e-184 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 haloacid dehalogenase-like hydrolase
LOFAKCML_00724 0.0 fusA1 - - J - - - elongation factor G
LOFAKCML_00725 6.34e-172 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LOFAKCML_00726 1.78e-218 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
LOFAKCML_00727 2.25e-166 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LOFAKCML_00728 8.52e-167 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LOFAKCML_00729 2.58e-52 - - - - - - - -
LOFAKCML_00730 4.97e-24 - - - - - - - -
LOFAKCML_00731 1.6e-133 - - - E - - - GDSL-like Lipase/Acylhydrolase
LOFAKCML_00732 4.21e-224 ydbI - - K - - - AI-2E family transporter
LOFAKCML_00733 3.33e-102 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
LOFAKCML_00734 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
LOFAKCML_00735 8.77e-100 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
LOFAKCML_00736 4.63e-78 - - - S - - - Domain of unknown function (DUF4430)
LOFAKCML_00737 6.12e-112 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
LOFAKCML_00738 3.65e-128 - - - S - - - Cob(I)alamin adenosyltransferase
LOFAKCML_00739 5.71e-192 - - - S - - - Putative ABC-transporter type IV
LOFAKCML_00740 6.3e-308 - - - S - - - LPXTG cell wall anchor motif
LOFAKCML_00741 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LOFAKCML_00742 0.0 - - - V - - - Restriction endonuclease
LOFAKCML_00743 4.77e-125 - - - K - - - Bacterial regulatory proteins, tetR family
LOFAKCML_00744 6.43e-183 - - - K ko:K09705 - ko00000 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LOFAKCML_00745 1.52e-238 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
LOFAKCML_00746 1.22e-179 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
LOFAKCML_00747 3.37e-220 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
LOFAKCML_00748 9.25e-82 - - - S - - - Domain of unknown function (DUF956)
LOFAKCML_00749 3.67e-57 - - - K - - - Transcriptional regulator
LOFAKCML_00750 7.14e-75 - - - K - - - Transcriptional regulator
LOFAKCML_00751 1.95e-74 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
LOFAKCML_00752 1.22e-15 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
LOFAKCML_00753 1.11e-299 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
LOFAKCML_00754 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
LOFAKCML_00755 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LOFAKCML_00756 1.8e-28 - - - - - - - -
LOFAKCML_00757 1.15e-127 - - - E - - - amino acid
LOFAKCML_00758 3.3e-55 - - - - - - - -
LOFAKCML_00759 7.38e-111 - - - M - - - LPXTG-motif cell wall anchor domain protein
LOFAKCML_00760 2.86e-41 - - - S - - - LPXTG cell wall anchor motif
LOFAKCML_00761 2.62e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LOFAKCML_00762 1.75e-137 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
LOFAKCML_00763 1.85e-48 - - - - - - - -
LOFAKCML_00764 1.77e-93 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
LOFAKCML_00765 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
LOFAKCML_00766 5.22e-314 - - - S - - - TerB-C domain
LOFAKCML_00767 6.6e-316 - - - P - - - P-loop Domain of unknown function (DUF2791)
LOFAKCML_00768 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
LOFAKCML_00769 4.75e-80 - - - - - - - -
LOFAKCML_00770 4.66e-178 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
LOFAKCML_00771 4.49e-50 - - - S - - - PD-(D/E)XK nuclease family transposase
LOFAKCML_00774 1.18e-165 - - - K ko:K03710 - ko00000,ko03000 UTRA
LOFAKCML_00775 2.85e-290 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
LOFAKCML_00776 9.56e-317 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LOFAKCML_00777 3.96e-126 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LOFAKCML_00778 4.53e-139 - - - S - - - SNARE associated Golgi protein
LOFAKCML_00779 4.02e-196 - - - I - - - alpha/beta hydrolase fold
LOFAKCML_00780 9.35e-161 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
LOFAKCML_00781 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LOFAKCML_00782 1.2e-207 - - - - - - - -
LOFAKCML_00783 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
LOFAKCML_00784 3.9e-125 yobS - - K - - - Bacterial regulatory proteins, tetR family
LOFAKCML_00785 8.59e-203 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
LOFAKCML_00786 1.36e-214 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
LOFAKCML_00787 7.08e-309 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
LOFAKCML_00788 0.0 - - - S - - - Zn-dependent metallo-hydrolase RNA specificity domain
LOFAKCML_00789 6.84e-188 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LOFAKCML_00790 1.15e-202 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
LOFAKCML_00791 6.35e-255 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
LOFAKCML_00792 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LOFAKCML_00793 5.95e-203 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
LOFAKCML_00794 1.79e-216 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
LOFAKCML_00795 2.96e-202 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LOFAKCML_00796 3.25e-137 yviA - - S - - - Protein of unknown function (DUF421)
LOFAKCML_00797 1.56e-36 - - - S - - - Protein of unknown function (DUF3290)
LOFAKCML_00798 1.91e-180 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
LOFAKCML_00799 1.11e-180 - - - - - - - -
LOFAKCML_00800 9.13e-75 - - - S - - - PAS domain
LOFAKCML_00801 2.25e-71 - - - S - - - PAS domain
LOFAKCML_00802 6.38e-232 - - - S - - - AAA domain
LOFAKCML_00803 1.98e-163 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LOFAKCML_00804 4.73e-31 - - - - - - - -
LOFAKCML_00805 5.3e-209 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
LOFAKCML_00806 6.64e-162 - - - G - - - Belongs to the phosphoglycerate mutase family
LOFAKCML_00807 3.13e-173 - - - S ko:K07090 - ko00000 membrane transporter protein
LOFAKCML_00808 1.63e-81 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LOFAKCML_00809 1.22e-139 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
LOFAKCML_00810 3.32e-93 yhaH - - S - - - Protein of unknown function (DUF805)
LOFAKCML_00811 1.01e-87 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
LOFAKCML_00812 1.87e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LOFAKCML_00813 3.02e-183 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LOFAKCML_00814 5.22e-179 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LOFAKCML_00815 1.45e-190 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LOFAKCML_00816 2.69e-195 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LOFAKCML_00817 3.16e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
LOFAKCML_00818 1.8e-218 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LOFAKCML_00819 3.82e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LOFAKCML_00820 1.46e-73 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LOFAKCML_00821 1.89e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
LOFAKCML_00822 3.13e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LOFAKCML_00823 2.61e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LOFAKCML_00824 7.24e-301 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LOFAKCML_00825 1.73e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
LOFAKCML_00826 2.22e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
LOFAKCML_00827 2.63e-110 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LOFAKCML_00828 1.05e-72 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LOFAKCML_00829 5.05e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LOFAKCML_00830 2.28e-89 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LOFAKCML_00831 1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LOFAKCML_00832 2.9e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LOFAKCML_00833 6.92e-45 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LOFAKCML_00834 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LOFAKCML_00835 4.48e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LOFAKCML_00836 1.45e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
LOFAKCML_00837 1.66e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LOFAKCML_00838 3.03e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LOFAKCML_00839 9.07e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LOFAKCML_00840 2.94e-60 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LOFAKCML_00841 1.91e-196 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LOFAKCML_00842 3.16e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LOFAKCML_00843 2.23e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
LOFAKCML_00844 3.29e-146 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LOFAKCML_00845 6.34e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
LOFAKCML_00846 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LOFAKCML_00847 1.39e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LOFAKCML_00848 7.28e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LOFAKCML_00849 1.56e-156 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
LOFAKCML_00850 2.47e-11 - - - V - - - Beta-lactamase
LOFAKCML_00851 1.95e-131 - - - V - - - Beta-lactamase
LOFAKCML_00852 1.61e-136 - - - K ko:K06977 - ko00000 acetyltransferase
LOFAKCML_00853 1.91e-124 - - - - - - - -
LOFAKCML_00854 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
LOFAKCML_00855 1.79e-170 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
LOFAKCML_00856 1.11e-239 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
LOFAKCML_00857 2.08e-21 - - - - - - - -
LOFAKCML_00858 1.76e-160 - - - - - - - -
LOFAKCML_00859 9.94e-304 - - - S - - - response to antibiotic
LOFAKCML_00860 4.31e-25 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
LOFAKCML_00861 8.45e-160 gpm2 - - G - - - Phosphoglycerate mutase family
LOFAKCML_00862 1.23e-158 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
LOFAKCML_00863 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LOFAKCML_00864 8.97e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
LOFAKCML_00865 1.51e-139 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
LOFAKCML_00866 5.9e-190 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
LOFAKCML_00867 1.42e-102 yjcF - - S - - - Acetyltransferase (GNAT) domain
LOFAKCML_00868 2.29e-131 - - - E - - - GDSL-like Lipase/Acylhydrolase
LOFAKCML_00869 7.88e-219 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
LOFAKCML_00870 2.28e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LOFAKCML_00871 7.58e-304 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
LOFAKCML_00872 1.95e-118 - - - S - - - Peptidase propeptide and YPEB domain
LOFAKCML_00873 9.4e-89 yybA - - K - - - Transcriptional regulator
LOFAKCML_00874 1.46e-111 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LOFAKCML_00875 7.94e-104 - - - S - - - Peptidase propeptide and YPEB domain
LOFAKCML_00876 1.08e-122 - - - F - - - Nucleoside 2-deoxyribosyltransferase
LOFAKCML_00877 1.34e-235 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LOFAKCML_00878 2.91e-229 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
LOFAKCML_00879 0.0 - - - V - - - ABC transporter transmembrane region
LOFAKCML_00880 2.6e-194 - - - S - - - reductase
LOFAKCML_00881 2.01e-178 yxeH - - S - - - hydrolase
LOFAKCML_00882 2.84e-21 gyaR 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LOFAKCML_00883 6.35e-173 gyaR 1.1.1.26, 1.1.1.399, 1.1.1.95 - CH ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LOFAKCML_00884 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
LOFAKCML_00885 3.4e-33 yngC - - S - - - SNARE associated Golgi protein
LOFAKCML_00886 2.12e-80 yngC - - S - - - SNARE associated Golgi protein
LOFAKCML_00887 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LOFAKCML_00888 1.55e-308 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LOFAKCML_00889 0.0 oatA - - I - - - Acyltransferase
LOFAKCML_00890 3.02e-226 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LOFAKCML_00891 1.13e-181 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LOFAKCML_00892 7.74e-47 - - - S - - - Lipopolysaccharide assembly protein A domain
LOFAKCML_00893 3.62e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
LOFAKCML_00894 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LOFAKCML_00895 2.72e-42 - - - S - - - Protein of unknown function (DUF2929)
LOFAKCML_00896 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
LOFAKCML_00897 6.65e-234 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LOFAKCML_00898 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
LOFAKCML_00899 2.98e-214 yitL - - S ko:K00243 - ko00000 S1 domain
LOFAKCML_00900 1.48e-216 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
LOFAKCML_00901 5.23e-77 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LOFAKCML_00902 3e-168 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LOFAKCML_00903 6.71e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LOFAKCML_00904 1.82e-165 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LOFAKCML_00905 1.53e-148 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LOFAKCML_00906 0.0 - - - E - - - Amino acid permease
LOFAKCML_00908 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LOFAKCML_00909 9.51e-119 - - - S - - - VanZ like family
LOFAKCML_00910 2.3e-170 yebC - - K - - - Transcriptional regulatory protein
LOFAKCML_00911 1.33e-226 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
LOFAKCML_00912 3.08e-221 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
LOFAKCML_00913 2.93e-64 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
LOFAKCML_00914 5.84e-95 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
LOFAKCML_00915 1.18e-55 - - - - - - - -
LOFAKCML_00916 9.9e-105 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
LOFAKCML_00917 4.89e-238 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
LOFAKCML_00918 1.77e-280 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LOFAKCML_00920 2.64e-50 - - - M - - - Protein of unknown function (DUF3737)
LOFAKCML_00921 1.64e-40 - - - M - - - Protein of unknown function (DUF3737)
LOFAKCML_00922 9.5e-285 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
LOFAKCML_00923 9.25e-221 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LOFAKCML_00924 5.73e-80 - - - S - - - SdpI/YhfL protein family
LOFAKCML_00925 4.46e-167 - - - K - - - Transcriptional regulatory protein, C terminal
LOFAKCML_00926 0.0 yclK - - T - - - Histidine kinase
LOFAKCML_00927 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LOFAKCML_00928 5.28e-139 vanZ - - V - - - VanZ like family
LOFAKCML_00929 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
LOFAKCML_00930 1.89e-19 - - - EGP - - - Major Facilitator
LOFAKCML_00931 3.42e-219 - - - EGP - - - Major Facilitator
LOFAKCML_00932 2.36e-247 ampC - - V - - - Beta-lactamase
LOFAKCML_00935 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
LOFAKCML_00936 4.94e-146 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
LOFAKCML_00937 7.36e-234 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LOFAKCML_00938 8.44e-201 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LOFAKCML_00939 3.08e-241 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LOFAKCML_00940 1.84e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LOFAKCML_00941 4.82e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
LOFAKCML_00942 4.83e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LOFAKCML_00943 4.97e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LOFAKCML_00944 1.54e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LOFAKCML_00945 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LOFAKCML_00946 8.2e-219 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LOFAKCML_00947 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LOFAKCML_00948 2.02e-92 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
LOFAKCML_00949 4.22e-41 - - - S - - - Protein of unknown function (DUF1146)
LOFAKCML_00950 7.96e-226 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
LOFAKCML_00951 4.39e-66 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
LOFAKCML_00952 8.85e-47 - - - S - - - Protein of unknown function (DUF2969)
LOFAKCML_00953 5.87e-276 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
LOFAKCML_00954 7.77e-103 uspA - - T - - - universal stress protein
LOFAKCML_00955 4.53e-55 - - - - - - - -
LOFAKCML_00956 1.61e-307 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
LOFAKCML_00957 1.76e-104 - - - S - - - Protein of unknown function (DUF1694)
LOFAKCML_00958 2.95e-140 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LOFAKCML_00959 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LOFAKCML_00960 8.68e-277 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
LOFAKCML_00961 6.56e-293 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LOFAKCML_00962 1.05e-42 - - - K - - - Helix-turn-helix domain
LOFAKCML_00963 7.73e-107 - - - K - - - Helix-turn-helix domain
LOFAKCML_00964 5.21e-164 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LOFAKCML_00965 2.95e-21 - - - K - - - Helix-turn-helix domain
LOFAKCML_00966 9.39e-85 - - - - - - - -
LOFAKCML_00967 7.78e-85 - - - S - - - Psort location Cytoplasmic, score
LOFAKCML_00969 1.81e-78 B4168_4126 - - L ko:K07493 - ko00000 Transposase
LOFAKCML_00970 2.27e-275 - - - - - - - -
LOFAKCML_00971 1.77e-156 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LOFAKCML_00972 1.64e-72 ytpP - - CO - - - Thioredoxin
LOFAKCML_00973 7.82e-161 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LOFAKCML_00974 2.26e-269 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LOFAKCML_00975 9.02e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LOFAKCML_00976 6.86e-72 - - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
LOFAKCML_00977 3.94e-103 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
LOFAKCML_00978 3.49e-56 - - - - - - - -
LOFAKCML_00979 5.64e-200 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LOFAKCML_00980 1.69e-97 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
LOFAKCML_00981 1.16e-241 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
LOFAKCML_00982 0.0 yhaN - - L - - - AAA domain
LOFAKCML_00983 3.37e-291 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
LOFAKCML_00984 2.07e-73 yheA - - S - - - Belongs to the UPF0342 family
LOFAKCML_00985 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LOFAKCML_00986 7.82e-204 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LOFAKCML_00987 3.87e-12 - - - C - - - FMN-dependent dehydrogenase
LOFAKCML_00988 2.42e-148 mgtC3 - - S ko:K07507 - ko00000,ko02000 MgtC family
LOFAKCML_00989 6.12e-179 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LOFAKCML_00990 5.23e-158 ptcC - - U ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LOFAKCML_00991 1.06e-116 ptcC - - U ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LOFAKCML_00992 7.21e-112 yecA - - K - - - Helix-turn-helix domain, rpiR family
LOFAKCML_00993 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LOFAKCML_00994 8.14e-73 - - - - - - - -
LOFAKCML_00995 1.23e-189 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
LOFAKCML_00996 3.33e-63 - - - C - - - Domain of unknown function (DUF4931)
LOFAKCML_00997 6.42e-154 - - - - - - - -
LOFAKCML_00998 6.89e-182 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
LOFAKCML_00999 1.14e-179 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
LOFAKCML_01000 2.86e-143 - - - G - - - phosphoglycerate mutase
LOFAKCML_01001 1.15e-121 - - - K - - - Bacterial regulatory proteins, tetR family
LOFAKCML_01002 3.36e-230 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
LOFAKCML_01003 3.81e-151 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LOFAKCML_01004 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LOFAKCML_01005 1.03e-49 - - - - - - - -
LOFAKCML_01006 1.18e-140 - - - K - - - WHG domain
LOFAKCML_01007 1.14e-123 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
LOFAKCML_01008 4.28e-125 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
LOFAKCML_01009 4.51e-192 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
LOFAKCML_01010 6.37e-231 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LOFAKCML_01011 7.09e-113 cvpA - - S - - - Colicin V production protein
LOFAKCML_01012 5.42e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
LOFAKCML_01013 3.14e-191 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LOFAKCML_01014 2.77e-175 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
LOFAKCML_01015 2.29e-196 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LOFAKCML_01016 1.83e-58 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
LOFAKCML_01017 1.97e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LOFAKCML_01018 2.2e-177 - - - S - - - Protein of unknown function (DUF1129)
LOFAKCML_01019 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
LOFAKCML_01020 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
LOFAKCML_01021 4.82e-156 vanR - - K - - - response regulator
LOFAKCML_01022 2.54e-267 - - - T - - - His Kinase A (phosphoacceptor) domain
LOFAKCML_01023 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LOFAKCML_01024 3.86e-186 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
LOFAKCML_01026 4.02e-283 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LOFAKCML_01027 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
LOFAKCML_01028 4.42e-249 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
LOFAKCML_01029 2.59e-314 - - - S - - - SLAP domain
LOFAKCML_01030 6e-184 lacR - - K - - - helix_turn_helix, arabinose operon control protein
LOFAKCML_01031 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
LOFAKCML_01032 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
LOFAKCML_01033 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
LOFAKCML_01034 1.27e-37 - - - T - - - Region found in RelA / SpoT proteins
LOFAKCML_01035 1.34e-38 - - - T - - - Region found in RelA / SpoT proteins
LOFAKCML_01036 3.01e-51 dltr - - K - - - response regulator
LOFAKCML_01037 1.59e-125 sptS - - T - - - Histidine kinase
LOFAKCML_01038 2.78e-71 sptS - - T - - - Histidine kinase
LOFAKCML_01039 1.85e-264 - - - EGP - - - Major Facilitator Superfamily
LOFAKCML_01040 5.12e-92 - - - O - - - OsmC-like protein
LOFAKCML_01041 1.23e-161 - - - S - - - L-ascorbic acid biosynthetic process
LOFAKCML_01042 9.19e-135 - - - - - - - -
LOFAKCML_01043 8.17e-233 - - - - - - - -
LOFAKCML_01044 0.0 potE - - E - - - Amino Acid
LOFAKCML_01045 2.3e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LOFAKCML_01046 2.87e-249 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
LOFAKCML_01049 6.38e-53 - - - - - - - -
LOFAKCML_01050 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LOFAKCML_01051 8.07e-42 - - - - - - - -
LOFAKCML_01052 1.03e-40 - - - S - - - Pyridoxamine 5'-phosphate oxidase
LOFAKCML_01053 1.08e-87 yobV3 - - K - - - WYL domain
LOFAKCML_01054 1.98e-60 yobV3 - - K - - - WYL domain
LOFAKCML_01055 2.4e-89 - - - S - - - pyridoxamine 5-phosphate
LOFAKCML_01056 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
LOFAKCML_01057 1.68e-178 - - - K - - - Transcriptional regulator
LOFAKCML_01058 3.7e-99 - - - S - - - NADPH-dependent FMN reductase
LOFAKCML_01059 1.39e-41 adh1 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
LOFAKCML_01060 7.49e-67 adh1 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
LOFAKCML_01061 8.38e-62 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
LOFAKCML_01062 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
LOFAKCML_01063 2.95e-43 - - - C - - - Heavy-metal-associated domain
LOFAKCML_01064 4.77e-118 dpsB - - P - - - Belongs to the Dps family
LOFAKCML_01065 1.39e-141 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
LOFAKCML_01066 6.94e-117 - - - K - - - Acetyltransferase (GNAT) family
LOFAKCML_01067 3.83e-196 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
LOFAKCML_01068 9.35e-36 - - - L ko:K07478 - ko00000 AAA C-terminal domain
LOFAKCML_01069 1.37e-229 - - - L ko:K07478 - ko00000 AAA C-terminal domain
LOFAKCML_01070 3.51e-54 - - - - - - - -
LOFAKCML_01071 0.0 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
LOFAKCML_01072 1.98e-64 - - - - - - - -
LOFAKCML_01073 3.82e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
LOFAKCML_01074 1.67e-74 yloU - - S - - - Asp23 family, cell envelope-related function
LOFAKCML_01075 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
LOFAKCML_01076 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LOFAKCML_01077 4.31e-232 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LOFAKCML_01078 8.89e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LOFAKCML_01079 2.11e-249 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LOFAKCML_01080 3.41e-231 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LOFAKCML_01081 7.39e-226 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LOFAKCML_01082 1.56e-190 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LOFAKCML_01083 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LOFAKCML_01084 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LOFAKCML_01085 1.56e-161 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LOFAKCML_01086 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
LOFAKCML_01087 3.45e-234 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LOFAKCML_01088 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LOFAKCML_01089 1.63e-65 - - - - - - - -
LOFAKCML_01090 1.98e-208 - - - S - - - Domain of unknown function (DUF389)
LOFAKCML_01091 3.29e-52 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
LOFAKCML_01092 7.28e-242 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
LOFAKCML_01093 2.8e-72 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LOFAKCML_01094 4.77e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
LOFAKCML_01095 1.23e-75 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LOFAKCML_01096 1.51e-121 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
LOFAKCML_01097 4.77e-270 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
LOFAKCML_01098 2.14e-154 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LOFAKCML_01099 1.12e-141 yqeK - - H - - - Hydrolase, HD family
LOFAKCML_01100 2.08e-77 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LOFAKCML_01101 2.57e-272 ylbM - - S - - - Belongs to the UPF0348 family
LOFAKCML_01102 8.27e-124 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
LOFAKCML_01103 2.03e-162 csrR - - K - - - response regulator
LOFAKCML_01104 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LOFAKCML_01105 9.66e-110 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
LOFAKCML_01106 1.17e-202 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LOFAKCML_01107 9.28e-58 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
LOFAKCML_01108 3.67e-178 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LOFAKCML_01109 1.4e-80 yodB - - K - - - Transcriptional regulator, HxlR family
LOFAKCML_01110 1.06e-256 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LOFAKCML_01111 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LOFAKCML_01112 2.74e-89 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LOFAKCML_01113 9.25e-217 ldh3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
LOFAKCML_01114 1.18e-51 - - - K - - - Helix-turn-helix domain
LOFAKCML_01115 6.43e-270 - - - S - - - SLAP domain
LOFAKCML_01116 3.64e-224 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LOFAKCML_01117 4.99e-189 - - - GK - - - ROK family
LOFAKCML_01118 5.78e-57 - - - - - - - -
LOFAKCML_01119 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
LOFAKCML_01120 3.92e-86 - - - S - - - Domain of unknown function (DUF1934)
LOFAKCML_01121 4.53e-98 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LOFAKCML_01122 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LOFAKCML_01123 5.19e-310 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LOFAKCML_01124 1.57e-97 - - - S - - - Haloacid dehalogenase-like hydrolase
LOFAKCML_01125 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LOFAKCML_01126 1.16e-204 msmR - - K - - - AraC-like ligand binding domain
LOFAKCML_01127 8.87e-287 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
LOFAKCML_01128 2.18e-132 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LOFAKCML_01129 1.4e-108 - - - K - - - DNA-binding helix-turn-helix protein
LOFAKCML_01130 5.26e-63 - - - K - - - Helix-turn-helix
LOFAKCML_01131 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
LOFAKCML_01133 2.72e-314 yifK - - E ko:K03293 - ko00000 Amino acid permease
LOFAKCML_01134 1.3e-239 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LOFAKCML_01135 1.92e-123 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LOFAKCML_01136 2.08e-21 ps301 - - K - - - sequence-specific DNA binding
LOFAKCML_01137 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
LOFAKCML_01138 3.21e-208 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LOFAKCML_01139 1.46e-240 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LOFAKCML_01140 6.62e-129 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LOFAKCML_01141 4.08e-47 - - - - - - - -
LOFAKCML_01142 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LOFAKCML_01143 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
LOFAKCML_01144 2.34e-105 - - - M - - - domain protein
LOFAKCML_01146 7.82e-211 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LOFAKCML_01147 7.17e-43 - - - M - - - Rib/alpha-like repeat
LOFAKCML_01148 1.71e-17 - - - S - - - Protein of unknown function (DUF1211)
LOFAKCML_01149 2.8e-35 - - - - - - - -
LOFAKCML_01150 2.36e-112 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
LOFAKCML_01151 2.25e-241 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LOFAKCML_01152 2.2e-173 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
LOFAKCML_01153 2.6e-183 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
LOFAKCML_01154 1.2e-200 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LOFAKCML_01155 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
LOFAKCML_01156 6.93e-96 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
LOFAKCML_01157 5.23e-102 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LOFAKCML_01158 1.27e-292 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LOFAKCML_01159 1.09e-164 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
LOFAKCML_01160 3.34e-215 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
LOFAKCML_01161 1.53e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LOFAKCML_01162 1.28e-230 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LOFAKCML_01163 4.15e-103 - - - K - - - Transcriptional regulator
LOFAKCML_01164 5.77e-102 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LOFAKCML_01165 1.22e-236 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
LOFAKCML_01166 4.53e-41 - - - S - - - Transglycosylase associated protein
LOFAKCML_01167 2.07e-74 - - - L - - - Resolvase, N terminal domain
LOFAKCML_01168 8.07e-51 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
LOFAKCML_01169 1.04e-93 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
LOFAKCML_01170 1.5e-69 - - - L - - - Transposase and inactivated derivatives, IS30 family
LOFAKCML_01171 1.64e-105 - - - L - - - Transposase and inactivated derivatives, IS30 family
LOFAKCML_01172 6.09e-106 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
LOFAKCML_01173 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
LOFAKCML_01174 5.12e-101 - - - C - - - Flavodoxin
LOFAKCML_01175 9.85e-147 - - - I - - - Acid phosphatase homologues
LOFAKCML_01176 8.48e-145 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
LOFAKCML_01177 2.52e-263 - - - V - - - Beta-lactamase
LOFAKCML_01178 3.04e-191 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
LOFAKCML_01179 3.35e-119 - - - S - - - ECF-type riboflavin transporter, S component
LOFAKCML_01180 1.18e-293 - - - S - - - Putative peptidoglycan binding domain
LOFAKCML_01181 2.37e-74 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
LOFAKCML_01182 1.58e-202 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
LOFAKCML_01183 0.0 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
LOFAKCML_01184 9.66e-46 - - - - - - - -
LOFAKCML_01185 5.03e-20 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
LOFAKCML_01186 4.35e-31 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
LOFAKCML_01187 1.63e-79 - - - - - - - -
LOFAKCML_01188 0.0 - - - P ko:K06148 - ko00000,ko02000 ABC transporter
LOFAKCML_01189 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
LOFAKCML_01190 1.94e-125 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
LOFAKCML_01191 3.06e-77 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
LOFAKCML_01192 1.24e-139 ytlR - - I - - - Diacylglycerol kinase catalytic domain
LOFAKCML_01193 2.23e-35 ytlR - - I - - - Diacylglycerol kinase catalytic domain
LOFAKCML_01194 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LOFAKCML_01195 9e-46 ykzG - - S - - - Belongs to the UPF0356 family
LOFAKCML_01196 1.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LOFAKCML_01197 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
LOFAKCML_01198 3.86e-263 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LOFAKCML_01199 1.72e-71 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
LOFAKCML_01200 5e-124 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
LOFAKCML_01201 6.77e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LOFAKCML_01202 3.91e-245 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
LOFAKCML_01203 9.86e-130 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
LOFAKCML_01204 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
LOFAKCML_01205 2.75e-221 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
LOFAKCML_01206 4.42e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
LOFAKCML_01207 1.48e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LOFAKCML_01208 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LOFAKCML_01209 1.98e-193 - - - - - - - -
LOFAKCML_01210 6.72e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LOFAKCML_01211 2.28e-278 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LOFAKCML_01212 5.7e-299 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LOFAKCML_01213 1.31e-135 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
LOFAKCML_01214 0.0 potE - - E - - - Amino Acid
LOFAKCML_01215 1.16e-241 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LOFAKCML_01216 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LOFAKCML_01217 9.49e-317 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LOFAKCML_01218 2.94e-108 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LOFAKCML_01219 2.32e-280 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LOFAKCML_01220 3.65e-222 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LOFAKCML_01221 3.67e-180 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LOFAKCML_01222 3.01e-272 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LOFAKCML_01223 1.43e-251 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LOFAKCML_01224 1.06e-260 pbpX1 - - V - - - Beta-lactamase
LOFAKCML_01225 2.04e-134 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
LOFAKCML_01226 0.0 - - - I - - - Protein of unknown function (DUF2974)
LOFAKCML_01227 2.91e-47 - - - C - - - FMN_bind
LOFAKCML_01228 2.6e-107 - - - - - - - -
LOFAKCML_01229 2.57e-221 iunH 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
LOFAKCML_01230 7.61e-217 ydhF - - S - - - Aldo keto reductase
LOFAKCML_01231 1.13e-243 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LOFAKCML_01232 1.37e-63 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LOFAKCML_01233 7.6e-159 - - - K ko:K03492 - ko00000,ko03000 UTRA
LOFAKCML_01234 1.17e-110 yfhC - - C - - - nitroreductase
LOFAKCML_01235 1.68e-52 - - - S - - - Domain of unknown function (DUF4767)
LOFAKCML_01236 1.23e-311 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LOFAKCML_01237 2.27e-167 - - - S - - - Uncharacterised protein, DegV family COG1307
LOFAKCML_01238 1.26e-126 - - - I - - - PAP2 superfamily
LOFAKCML_01239 2.94e-117 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LOFAKCML_01240 5.43e-48 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LOFAKCML_01242 1.12e-213 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LOFAKCML_01245 2.5e-278 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LOFAKCML_01246 0.0 mdr - - EGP - - - Major Facilitator
LOFAKCML_01247 4.22e-186 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LOFAKCML_01248 2.45e-151 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
LOFAKCML_01249 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
LOFAKCML_01250 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
LOFAKCML_01251 1.44e-229 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
LOFAKCML_01252 2.96e-30 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
LOFAKCML_01253 2.74e-81 - - - M - - - LPXTG-motif cell wall anchor domain protein
LOFAKCML_01254 6.68e-29 - - - - - - - -
LOFAKCML_01255 1.04e-76 - - - CO ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin
LOFAKCML_01256 8.05e-149 - - - K - - - Rhodanese Homology Domain
LOFAKCML_01257 4.43e-221 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LOFAKCML_01258 4.81e-21 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
LOFAKCML_01259 2.26e-17 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
LOFAKCML_01260 1.94e-55 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
LOFAKCML_01261 1.54e-37 - - - S - - - PD-(D/E)XK nuclease family transposase
LOFAKCML_01262 1.77e-61 - - - - - - - -
LOFAKCML_01263 6.17e-198 mutR - - K - - - Helix-turn-helix XRE-family like proteins
LOFAKCML_01264 7e-103 - - - S - - - Putative adhesin
LOFAKCML_01265 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
LOFAKCML_01266 1.37e-63 yoeB - - S ko:K19158 - ko00000,ko01000,ko02048 YoeB-like toxin of bacterial type II toxin-antitoxin system
LOFAKCML_01267 9e-66 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
LOFAKCML_01268 1.06e-258 napA - - P - - - Sodium/hydrogen exchanger family
LOFAKCML_01269 0.0 cadA - - P - - - P-type ATPase
LOFAKCML_01270 1.69e-107 ykuL - - S - - - (CBS) domain
LOFAKCML_01271 3.66e-274 - - - S - - - Membrane
LOFAKCML_01272 2.34e-66 - - - - - - - -
LOFAKCML_01273 3.2e-27 - - - S - - - D-Ala-teichoic acid biosynthesis protein
LOFAKCML_01274 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LOFAKCML_01275 2.08e-304 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
LOFAKCML_01276 1e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LOFAKCML_01277 1.05e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LOFAKCML_01278 2.66e-221 pbpX2 - - V - - - Beta-lactamase
LOFAKCML_01279 6.79e-105 - - - S - - - Threonine/Serine exporter, ThrE
LOFAKCML_01280 1.14e-177 - - - S - - - Putative threonine/serine exporter
LOFAKCML_01281 0.0 - - - S - - - ABC transporter
LOFAKCML_01282 2.34e-74 - - - - - - - -
LOFAKCML_01283 1.89e-127 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LOFAKCML_01284 7.04e-16 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
LOFAKCML_01285 6.96e-283 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LOFAKCML_01286 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
LOFAKCML_01287 1.34e-34 - - - S - - - Fic/DOC family
LOFAKCML_01288 1.12e-63 - - - S - - - Fic/DOC family
LOFAKCML_01289 2.19e-56 - - - S - - - Enterocin A Immunity
LOFAKCML_01290 6.67e-53 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
LOFAKCML_01291 7.52e-61 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
LOFAKCML_01292 7.01e-89 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
LOFAKCML_01293 3.14e-296 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LOFAKCML_01294 9.17e-172 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
LOFAKCML_01295 9.45e-152 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LOFAKCML_01296 2.98e-201 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LOFAKCML_01297 3.04e-154 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LOFAKCML_01298 1.79e-248 - - - S - - - DUF218 domain
LOFAKCML_01299 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LOFAKCML_01300 1.33e-126 - - - S - - - ECF transporter, substrate-specific component
LOFAKCML_01301 2.08e-203 - - - S - - - Aldo/keto reductase family
LOFAKCML_01302 7.74e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LOFAKCML_01303 3.09e-128 - - - K - - - rpiR family
LOFAKCML_01304 4.81e-100 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
LOFAKCML_01305 3.88e-50 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
LOFAKCML_01306 5.12e-233 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Beta-lactamase
LOFAKCML_01307 1.01e-161 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LOFAKCML_01308 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LOFAKCML_01309 6.34e-201 - - - - - - - -
LOFAKCML_01310 1.63e-204 - - - - - - - -
LOFAKCML_01311 9.11e-139 - - - - - - - -
LOFAKCML_01312 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
LOFAKCML_01313 7.4e-89 ynbB - - P - - - aluminum resistance
LOFAKCML_01314 1.58e-109 ynbB - - P - - - aluminum resistance
LOFAKCML_01315 1.89e-60 ynbB - - P - - - aluminum resistance
LOFAKCML_01316 6.8e-220 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LOFAKCML_01317 1.73e-89 yqhL - - P - - - Rhodanese-like protein
LOFAKCML_01318 2.45e-44 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
LOFAKCML_01319 8.58e-149 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
LOFAKCML_01320 1.27e-128 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LOFAKCML_01321 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LOFAKCML_01322 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LOFAKCML_01323 0.0 - - - S - - - membrane
LOFAKCML_01324 5.79e-217 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
LOFAKCML_01325 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 AAA domain (Cdc48 subfamily)
LOFAKCML_01326 2.75e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LOFAKCML_01327 6.21e-270 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LOFAKCML_01328 1.48e-159 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LOFAKCML_01329 1.38e-73 - - - M ko:K02004 - ko00000,ko00002,ko02000 Membrane
LOFAKCML_01330 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
LOFAKCML_01331 3.96e-49 - - - - - - - -
LOFAKCML_01332 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
LOFAKCML_01333 6.7e-200 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
LOFAKCML_01334 1.75e-156 - - - S - - - Protein of unknown function (DUF975)
LOFAKCML_01335 2.66e-64 - - - - - - - -
LOFAKCML_01336 6.93e-39 - - - - - - - -
LOFAKCML_01337 7.99e-37 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LOFAKCML_01338 1.37e-56 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LOFAKCML_01339 1.87e-11 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LOFAKCML_01341 1.26e-258 - - - G - - - Major Facilitator Superfamily
LOFAKCML_01342 5.86e-59 - - - - - - - -
LOFAKCML_01343 3.22e-33 - - - S - - - Domain of unknown function (DUF4160)
LOFAKCML_01344 4.75e-67 - - - O - - - Matrixin
LOFAKCML_01345 1.29e-297 eriC - - P ko:K03281 - ko00000 chloride
LOFAKCML_01346 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
LOFAKCML_01347 1.77e-212 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LOFAKCML_01348 1.92e-238 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LOFAKCML_01349 9.19e-312 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter
LOFAKCML_01350 6.81e-234 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
LOFAKCML_01351 3.88e-107 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
LOFAKCML_01352 2.04e-233 eriC - - P ko:K03281 - ko00000 chloride
LOFAKCML_01353 1.38e-48 - - - GK - - - ROK family
LOFAKCML_01354 3.27e-227 - - - L - - - COG3547 Transposase and inactivated derivatives
LOFAKCML_01355 1.84e-135 - - - K - - - Helix-turn-helix domain
LOFAKCML_01356 1.21e-124 - - - S - - - Bacteriocin helveticin-J
LOFAKCML_01357 4.65e-100 - - - S - - - SLAP domain
LOFAKCML_01358 6.55e-221 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
LOFAKCML_01359 1.74e-123 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
LOFAKCML_01360 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LOFAKCML_01361 3.63e-220 - - - K - - - helix_turn_helix, arabinose operon control protein
LOFAKCML_01362 3.17e-205 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
LOFAKCML_01363 2.37e-124 lemA - - S ko:K03744 - ko00000 LemA family
LOFAKCML_01364 1.07e-245 ysdE - - P - - - Citrate transporter
LOFAKCML_01365 1.36e-91 - - - S - - - Iron-sulphur cluster biosynthesis
LOFAKCML_01366 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
LOFAKCML_01367 7.64e-62 - - - - - - - -
LOFAKCML_01368 4.46e-228 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
LOFAKCML_01369 5.82e-157 - - - K - - - Protein of unknown function (DUF4065)
LOFAKCML_01370 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
LOFAKCML_01371 9.83e-260 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
LOFAKCML_01372 1.82e-260 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LOFAKCML_01373 2.94e-50 - - - - - - - -
LOFAKCML_01375 2.99e-239 - - - S - - - SLAP domain
LOFAKCML_01376 2.49e-48 - - - S - - - Protein of unknown function (DUF2922)
LOFAKCML_01377 7.02e-40 - - - - - - - -
LOFAKCML_01378 8.86e-09 - - - - - - - -
LOFAKCML_01380 1.63e-112 - - - - - - - -
LOFAKCML_01381 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
LOFAKCML_01382 5.61e-101 - - - KLT - - - serine threonine protein kinase
LOFAKCML_01383 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
LOFAKCML_01384 0.0 - - - L - - - Probable transposase
LOFAKCML_01385 1.25e-136 - - - L - - - Resolvase, N terminal domain
LOFAKCML_01386 1.14e-96 - - - S - - - Protein of unknown function (DUF3021)
LOFAKCML_01387 4.61e-97 - - - K - - - LytTr DNA-binding domain
LOFAKCML_01388 6.34e-136 - 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
LOFAKCML_01390 5.17e-08 - - - S - - - Protein of unknown function (DUF3923)
LOFAKCML_01391 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
LOFAKCML_01392 5.75e-124 - - - K - - - Acetyltransferase (GNAT) domain
LOFAKCML_01393 2.17e-112 - - - K - - - helix_turn_helix, mercury resistance
LOFAKCML_01396 1.31e-67 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
LOFAKCML_01397 2.73e-60 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
LOFAKCML_01398 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
LOFAKCML_01399 1.17e-73 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LOFAKCML_01400 4.67e-290 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LOFAKCML_01401 2.36e-60 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
LOFAKCML_01402 1.64e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LOFAKCML_01403 4e-174 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
LOFAKCML_01404 1.32e-73 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LOFAKCML_01405 3.84e-153 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
LOFAKCML_01406 5.3e-189 - - - E - - - GDSL-like Lipase/Acylhydrolase family
LOFAKCML_01407 1.99e-145 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LOFAKCML_01408 1.85e-49 ynzC - - S - - - UPF0291 protein
LOFAKCML_01409 6.43e-41 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
LOFAKCML_01410 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LOFAKCML_01411 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LOFAKCML_01412 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
LOFAKCML_01413 9.59e-289 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
LOFAKCML_01414 1.46e-145 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
LOFAKCML_01415 4.99e-252 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
LOFAKCML_01416 1.1e-180 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
LOFAKCML_01417 2.15e-236 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LOFAKCML_01418 2.38e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
LOFAKCML_01419 8.57e-122 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LOFAKCML_01420 4.49e-178 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LOFAKCML_01421 1.62e-189 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
LOFAKCML_01422 7.42e-253 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
LOFAKCML_01423 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LOFAKCML_01424 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LOFAKCML_01425 8.01e-107 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
LOFAKCML_01426 6.69e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
LOFAKCML_01427 9.2e-64 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
LOFAKCML_01428 5.4e-63 ylxQ - - J - - - ribosomal protein
LOFAKCML_01429 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LOFAKCML_01430 4.6e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LOFAKCML_01431 5.53e-210 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LOFAKCML_01432 6.52e-226 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
LOFAKCML_01433 1.19e-237 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LOFAKCML_01434 2.79e-115 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LOFAKCML_01435 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
LOFAKCML_01436 3.62e-268 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LOFAKCML_01437 1.13e-30 - - - - - - - -
LOFAKCML_01438 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LOFAKCML_01439 1.31e-149 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
LOFAKCML_01440 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
LOFAKCML_01441 8.09e-122 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LOFAKCML_01442 2.58e-14 - - - - - - - -
LOFAKCML_01443 5.88e-47 - - - - - - - -
LOFAKCML_01444 6.14e-44 - - - L - - - NUDIX domain
LOFAKCML_01445 9.99e-216 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
LOFAKCML_01446 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
LOFAKCML_01447 1.88e-18 - - - S - - - PD-(D/E)XK nuclease family transposase
LOFAKCML_01448 1.46e-140 - - - S - - - PD-(D/E)XK nuclease family transposase
LOFAKCML_01449 8.58e-139 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
LOFAKCML_01450 1.9e-42 padR - - K - - - Virulence activator alpha C-term
LOFAKCML_01451 1.52e-65 padR - - K - - - Virulence activator alpha C-term
LOFAKCML_01452 9.06e-159 - - - M - - - ErfK YbiS YcfS YnhG
LOFAKCML_01453 1.75e-194 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LOFAKCML_01454 1.86e-303 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LOFAKCML_01456 7.41e-65 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
LOFAKCML_01457 7.5e-159 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
LOFAKCML_01458 2.66e-48 - - - S - - - Enterocin A Immunity
LOFAKCML_01459 4.39e-177 yxeH - - S - - - hydrolase
LOFAKCML_01460 2.43e-81 - - - S - - - Uncharacterised protein family (UPF0236)
LOFAKCML_01461 1.41e-239 - - - S - - - Cysteine-rich secretory protein family
LOFAKCML_01462 1.3e-282 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LOFAKCML_01464 3.04e-237 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LOFAKCML_01465 4.02e-186 epsB - - M - - - biosynthesis protein
LOFAKCML_01466 4.62e-160 ywqD - - D - - - Capsular exopolysaccharide family
LOFAKCML_01467 9.83e-188 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
LOFAKCML_01468 9.2e-156 epsE2 - - M - - - Bacterial sugar transferase
LOFAKCML_01469 8.19e-107 - - - M - - - Oligosaccharide biosynthesis protein Alg14 like
LOFAKCML_01470 3.73e-102 - - - S - - - Glycosyltransferase family 28 C-terminal domain
LOFAKCML_01471 9.96e-130 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
LOFAKCML_01472 3.87e-09 - - - M - - - Glycosyltransferase, group 1 family protein
LOFAKCML_01474 9.84e-75 - - - S - - - glycosyl transferase family 2
LOFAKCML_01476 2.99e-25 - - - S - - - Glycosyltransferase like family 2
LOFAKCML_01477 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LOFAKCML_01478 8.93e-163 treR - - K ko:K03486 - ko00000,ko03000 UTRA
LOFAKCML_01479 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
LOFAKCML_01480 0.0 - - - - - - - -
LOFAKCML_01481 2.03e-105 - - - - - - - -
LOFAKCML_01482 4.27e-142 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LOFAKCML_01483 3.21e-87 - - - S - - - ASCH domain
LOFAKCML_01484 6.24e-180 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
LOFAKCML_01485 3.85e-197 - - - L - - - helicase
LOFAKCML_01486 6.98e-217 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
LOFAKCML_01487 1.48e-125 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
LOFAKCML_01488 6.23e-244 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LOFAKCML_01489 4.53e-240 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
LOFAKCML_01490 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
LOFAKCML_01491 1.25e-241 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LOFAKCML_01492 1.81e-29 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
LOFAKCML_01493 1.92e-35 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
LOFAKCML_01494 2.47e-182 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
LOFAKCML_01495 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
LOFAKCML_01496 2.83e-111 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
LOFAKCML_01497 2.71e-53 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
LOFAKCML_01498 7.93e-167 - - - - - - - -
LOFAKCML_01499 5.97e-84 - 1.1.1.29 - CH ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LOFAKCML_01500 2.06e-97 - 1.1.1.29 - CH ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LOFAKCML_01501 3.86e-61 - - - - - - - -
LOFAKCML_01502 4.72e-72 - - - - - - - -
LOFAKCML_01503 1.15e-21 ptsG 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
LOFAKCML_01504 3.17e-28 ptsG 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
LOFAKCML_01505 1.1e-277 - - - EGP ko:K08196,ko:K08369 - ko00000,ko02000 Major Facilitator
LOFAKCML_01506 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LOFAKCML_01507 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
LOFAKCML_01508 9.52e-37 - - - Q - - - Imidazolonepropionase and related amidohydrolases
LOFAKCML_01509 1.87e-226 - - - Q - - - Imidazolonepropionase and related amidohydrolases
LOFAKCML_01510 3.6e-45 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
LOFAKCML_01511 0.0 - - - L - - - Transposase
LOFAKCML_01512 2.44e-25 - - - - - - - -
LOFAKCML_01513 2.02e-29 - - - L ko:K07484 - ko00000 IS66 Orf2 like protein
LOFAKCML_01514 2.9e-69 - - - S - - - SLAP domain
LOFAKCML_01515 1.38e-121 - - - S - - - SLAP domain
LOFAKCML_01517 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LOFAKCML_01518 2.77e-30 - - - - - - - -
LOFAKCML_01519 5.7e-44 - - - - - - - -
LOFAKCML_01520 4.13e-148 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
LOFAKCML_01521 9.35e-152 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
LOFAKCML_01522 9.75e-174 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LOFAKCML_01523 1.52e-206 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
LOFAKCML_01524 3.77e-68 yitW - - S - - - Iron-sulfur cluster assembly protein
LOFAKCML_01525 1.29e-123 - - - S - - - Cysteine-rich secretory protein family
LOFAKCML_01526 5.02e-20 - - - - - - - -
LOFAKCML_01527 6.77e-85 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
LOFAKCML_01528 1.12e-155 terC - - P - - - Integral membrane protein TerC family
LOFAKCML_01529 3.25e-81 yeaO - - S - - - Protein of unknown function, DUF488
LOFAKCML_01530 2.08e-157 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
LOFAKCML_01531 1.15e-38 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LOFAKCML_01532 3.52e-174 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LOFAKCML_01533 7.5e-201 - - - L - - - HNH nucleases
LOFAKCML_01534 2.94e-155 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
LOFAKCML_01536 5.75e-153 - - - G - - - Glycosyl hydrolases family 8
LOFAKCML_01537 2.34e-30 - - - G - - - Glycosyl hydrolases family 8
LOFAKCML_01538 2.32e-283 ydaM - - M - - - Glycosyl transferase family group 2
LOFAKCML_01539 1.39e-150 - - - - - - - -
LOFAKCML_01540 9.69e-25 - - - - - - - -
LOFAKCML_01541 1.64e-142 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
LOFAKCML_01542 5.6e-45 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LOFAKCML_01543 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LOFAKCML_01544 1.6e-220 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LOFAKCML_01545 2.87e-311 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LOFAKCML_01546 3.17e-187 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
LOFAKCML_01547 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
LOFAKCML_01548 9.22e-213 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LOFAKCML_01549 1.63e-148 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
LOFAKCML_01550 1.06e-159 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
LOFAKCML_01551 3.57e-61 - - - E - - - Zn peptidase
LOFAKCML_01552 6.83e-68 - - - K - - - Helix-turn-helix XRE-family like proteins
LOFAKCML_01554 2.58e-45 - - - - - - - -
LOFAKCML_01556 2.8e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
LOFAKCML_01557 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LOFAKCML_01558 8.07e-314 yycH - - S - - - YycH protein
LOFAKCML_01559 3.54e-190 yycI - - S - - - YycH protein
LOFAKCML_01560 8.73e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
LOFAKCML_01561 1.18e-274 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
LOFAKCML_01562 2.23e-117 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LOFAKCML_01563 3.64e-237 - - - S - - - Putative peptidoglycan binding domain
LOFAKCML_01564 1.58e-33 - - - - - - - -
LOFAKCML_01565 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
LOFAKCML_01566 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
LOFAKCML_01568 2.79e-77 lysM - - M - - - LysM domain
LOFAKCML_01569 8.23e-222 - - - - - - - -
LOFAKCML_01570 2.06e-289 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
LOFAKCML_01571 1.17e-29 repA - - S - - - Replication initiator protein A
LOFAKCML_01572 4.63e-50 - - - I - - - Carboxylesterase family
LOFAKCML_01573 4.9e-98 - - - I - - - Carboxylesterase family
LOFAKCML_01574 3.75e-133 - - - GM - - - NmrA-like family
LOFAKCML_01575 1.14e-41 - - - S ko:K18918 - ko00000,ko02048,ko03000 RelB antitoxin
LOFAKCML_01576 2.15e-144 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LOFAKCML_01577 1.32e-156 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LOFAKCML_01578 6.2e-212 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LOFAKCML_01579 1.68e-121 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LOFAKCML_01580 3.16e-231 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
LOFAKCML_01581 1.93e-302 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LOFAKCML_01582 1.3e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LOFAKCML_01583 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
LOFAKCML_01584 7.82e-11 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LOFAKCML_01585 4.69e-77 - - - - - - - -
LOFAKCML_01587 3.23e-40 - - - U ko:K05340 - ko00000,ko02000 sugar transport
LOFAKCML_01588 2.93e-124 - - - U ko:K05340 - ko00000,ko02000 sugar transport
LOFAKCML_01589 1.06e-62 - - - - - - - -
LOFAKCML_01590 4.3e-98 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
LOFAKCML_01591 2.11e-58 - - - - - - - -
LOFAKCML_01592 5.11e-106 - - - K - - - Acetyltransferase (GNAT) domain
LOFAKCML_01593 4.18e-190 - - - S - - - Protein of unknown function (DUF2785)
LOFAKCML_01594 9.76e-36 - - - S - - - MazG-like family
LOFAKCML_01595 1.32e-74 - - - - - - - -
LOFAKCML_01596 3.16e-61 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
LOFAKCML_01597 2.6e-15 - - - S - - - F420-0:Gamma-glutamyl ligase
LOFAKCML_01598 8.18e-99 - - - S - - - F420-0:Gamma-glutamyl ligase
LOFAKCML_01599 3.96e-65 - - - S - - - HicB family
LOFAKCML_01601 4.83e-101 - - - S - - - AAA domain
LOFAKCML_01602 2.18e-84 - - - F - - - NUDIX domain
LOFAKCML_01603 2.31e-180 - - - F - - - Phosphorylase superfamily
LOFAKCML_01604 4.05e-63 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
LOFAKCML_01605 6.08e-61 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
LOFAKCML_01606 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LOFAKCML_01607 1.66e-79 - - - S - - - Bacterial PH domain
LOFAKCML_01608 7.87e-37 - - - - - - - -
LOFAKCML_01609 1.55e-87 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
LOFAKCML_01610 7.13e-227 lipA - - I - - - Carboxylesterase family
LOFAKCML_01612 5.24e-264 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
LOFAKCML_01613 0.0 - - - S - - - Predicted membrane protein (DUF2207)
LOFAKCML_01614 4.18e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
LOFAKCML_01615 1.01e-161 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
LOFAKCML_01616 1.28e-253 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LOFAKCML_01617 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
LOFAKCML_01618 6.82e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
LOFAKCML_01619 5.95e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
LOFAKCML_01620 1.64e-261 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
LOFAKCML_01621 6.05e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LOFAKCML_01622 6.6e-91 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
LOFAKCML_01623 5.2e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LOFAKCML_01624 1.06e-195 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LOFAKCML_01625 5.59e-251 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LOFAKCML_01626 6.25e-47 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LOFAKCML_01627 3.57e-202 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LOFAKCML_01628 4.01e-194 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
LOFAKCML_01629 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
LOFAKCML_01630 2.46e-102 - - - S - - - ASCH
LOFAKCML_01631 4.54e-59 - - - - - - - -
LOFAKCML_01632 2.02e-107 - - - S - - - Domain of unknown function (DUF5067)
LOFAKCML_01633 4.45e-83 - - - - - - - -
LOFAKCML_01634 4.79e-63 - - - - - - - -
LOFAKCML_01635 3.56e-184 - - - F - - - Phosphorylase superfamily
LOFAKCML_01636 7.29e-106 - - - S - - - AAA domain
LOFAKCML_01637 4.11e-82 - 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
LOFAKCML_01638 2.87e-105 - - - S - - - F420-0:Gamma-glutamyl ligase
LOFAKCML_01639 4.37e-153 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
LOFAKCML_01640 6.26e-169 - - - F - - - Phosphorylase superfamily
LOFAKCML_01641 9.45e-99 codA - - F - - - Cytidine and deoxycytidylate deaminase zinc-binding region
LOFAKCML_01643 1.07e-104 - - - K - - - Acetyltransferase (GNAT) domain
LOFAKCML_01644 4.74e-68 - - - - - - - -
LOFAKCML_01652 1.14e-277 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
LOFAKCML_01653 1.28e-256 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
LOFAKCML_01654 2.25e-222 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LOFAKCML_01655 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LOFAKCML_01656 1.3e-40 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
LOFAKCML_01657 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LOFAKCML_01658 1.3e-100 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LOFAKCML_01660 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
LOFAKCML_01661 5.25e-166 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
LOFAKCML_01662 5.23e-151 - - - G - - - Antibiotic biosynthesis monooxygenase
LOFAKCML_01663 1.25e-128 - - - G - - - Histidine phosphatase superfamily (branch 1)
LOFAKCML_01664 2.77e-144 - - - G - - - Phosphoglycerate mutase family
LOFAKCML_01665 4.59e-248 - - - D - - - nuclear chromosome segregation
LOFAKCML_01666 8.58e-126 - - - M - - - LysM domain protein
LOFAKCML_01667 5.26e-19 - - - - - - - -
LOFAKCML_01668 3.85e-200 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
LOFAKCML_01669 4.63e-88 - - - - - - - -
LOFAKCML_01670 1.78e-42 - - - - - - - -
LOFAKCML_01671 3.36e-91 - - - S - - - Iron-sulphur cluster biosynthesis
LOFAKCML_01672 6.76e-168 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
LOFAKCML_01673 5.46e-145 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LOFAKCML_01674 1.21e-40 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
LOFAKCML_01676 2.03e-310 - 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LOFAKCML_01677 2.96e-94 - - - S - - - EamA-like transporter family
LOFAKCML_01678 1.57e-31 - - - I - - - bis(5'-adenosyl)-triphosphatase activity
LOFAKCML_01679 6.81e-85 - 3.6.1.17 - FG ko:K01518 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 bis(5'-adenosyl)-triphosphatase activity
LOFAKCML_01680 8.77e-46 csd2 - - E - - - PFAM aminotransferase class V
LOFAKCML_01681 1.02e-30 csd2 - - E - - - PFAM aminotransferase class V
LOFAKCML_01682 8.74e-259 - - - L - - - Belongs to the 'phage' integrase family
LOFAKCML_01683 2.6e-37 - - - - - - - -
LOFAKCML_01685 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
LOFAKCML_01686 4.32e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LOFAKCML_01687 2.15e-101 - - - K - - - LytTr DNA-binding domain
LOFAKCML_01688 4.89e-159 - - - S - - - membrane
LOFAKCML_01689 1.39e-230 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
LOFAKCML_01690 1.33e-289 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
LOFAKCML_01691 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LOFAKCML_01692 5.17e-30 - - - - - - - -
LOFAKCML_01693 1.06e-37 - - - S - - - Enterocin A Immunity
LOFAKCML_01694 1.73e-30 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
LOFAKCML_01695 6.17e-156 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
LOFAKCML_01696 3.01e-153 - - - S - - - PAS domain
LOFAKCML_01697 8.28e-176 nirC - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
LOFAKCML_01698 3.31e-262 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
LOFAKCML_01699 1.97e-140 pncA - - Q - - - Isochorismatase family
LOFAKCML_01700 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LOFAKCML_01701 2.58e-163 - - - F - - - NUDIX domain
LOFAKCML_01702 5.6e-94 - - - S - - - Iron-sulphur cluster biosynthesis
LOFAKCML_01703 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LOFAKCML_01704 0.0 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
LOFAKCML_01705 1.04e-20 - - - V - - - Abi-like protein
LOFAKCML_01706 7.82e-10 - - - V - - - Abi-like protein
LOFAKCML_01707 1.89e-128 - - - - - - - -
LOFAKCML_01708 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
LOFAKCML_01709 1.61e-175 - - - U ko:K05340 - ko00000,ko02000 sugar transport
LOFAKCML_01710 1.32e-34 - - - - - - - -
LOFAKCML_01711 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
LOFAKCML_01712 3.57e-80 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
LOFAKCML_01713 1.57e-82 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
LOFAKCML_01714 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
LOFAKCML_01715 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 DEAD/DEAH box helicase
LOFAKCML_01716 5.32e-295 tcaA - - S ko:K21463 - ko00000 response to antibiotic
LOFAKCML_01717 6.31e-29 - - - - - - - -
LOFAKCML_01718 1.1e-148 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
LOFAKCML_01719 1.68e-55 - - - S - - - Enterocin A Immunity
LOFAKCML_01720 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LOFAKCML_01721 1.39e-96 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
LOFAKCML_01722 2.11e-249 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LOFAKCML_01723 2.99e-107 dar 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
LOFAKCML_01724 5.19e-95 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LOFAKCML_01725 1.3e-244 - - - S - - - SLAP domain
LOFAKCML_01726 1.21e-179 - - - S - - - Bacteriocin helveticin-J
LOFAKCML_01727 3.8e-21 - - - S - - - Bacteriocin helveticin-J
LOFAKCML_01728 2.51e-203 - - - - - - - -
LOFAKCML_01729 1.25e-97 - - - K - - - Acetyltransferase (GNAT) domain
LOFAKCML_01730 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
LOFAKCML_01731 1.52e-119 - - - K - - - Bacterial regulatory proteins, tetR family
LOFAKCML_01732 3.95e-311 qacA - - EGP - - - Major Facilitator
LOFAKCML_01737 6.02e-124 - - - K - - - Acetyltransferase (GNAT) domain
LOFAKCML_01739 6.5e-38 cspA - - K ko:K03704 - ko00000,ko03000 Cold shock protein
LOFAKCML_01740 5.05e-312 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
LOFAKCML_01741 3.68e-230 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
LOFAKCML_01742 1.43e-117 ydhK - - M - - - Protein of unknown function (DUF1541)
LOFAKCML_01743 1.01e-51 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
LOFAKCML_01744 1.15e-47 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
LOFAKCML_01745 5.42e-19 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
LOFAKCML_01747 7.52e-83 - - - L - - - Transposase and inactivated derivatives IS30 family
LOFAKCML_01748 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LOFAKCML_01749 2.12e-309 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
LOFAKCML_01750 1.26e-68 - - - - - - - -
LOFAKCML_01751 7.31e-154 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
LOFAKCML_01752 5.08e-143 ybbB - - S - - - Protein of unknown function (DUF1211)
LOFAKCML_01753 2.65e-217 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
LOFAKCML_01754 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LOFAKCML_01755 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LOFAKCML_01756 2.94e-66 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LOFAKCML_01757 2e-264 camS - - S - - - sex pheromone
LOFAKCML_01758 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LOFAKCML_01759 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
LOFAKCML_01760 3.23e-140 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
LOFAKCML_01762 3.84e-113 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
LOFAKCML_01763 4.89e-176 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
LOFAKCML_01764 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
LOFAKCML_01765 8.98e-288 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LOFAKCML_01766 3.55e-53 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
LOFAKCML_01767 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
LOFAKCML_01768 9.45e-72 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
LOFAKCML_01769 1.34e-195 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LOFAKCML_01770 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LOFAKCML_01771 5.87e-256 - - - M - - - Glycosyl transferases group 1
LOFAKCML_01772 8.02e-171 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LOFAKCML_01773 2.16e-192 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
LOFAKCML_01774 5.67e-149 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
LOFAKCML_01775 7.12e-111 - - - S - - - Protein of unknown function (DUF1461)
LOFAKCML_01776 1.24e-187 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LOFAKCML_01777 5.15e-127 yutD - - S - - - Protein of unknown function (DUF1027)
LOFAKCML_01778 0.0 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LOFAKCML_01779 2.42e-74 - - - - - - - -
LOFAKCML_01780 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
LOFAKCML_01781 3.03e-187 - - - S - - - haloacid dehalogenase-like hydrolase
LOFAKCML_01782 1.13e-290 pbuG - - S ko:K06901 - ko00000,ko02000 permease
LOFAKCML_01783 4.42e-256 - - - S ko:K07133 - ko00000 cog cog1373
LOFAKCML_01784 1.09e-169 - - - K - - - helix_turn_helix, mercury resistance
LOFAKCML_01785 1e-289 pbuG - - S ko:K06901 - ko00000,ko02000 permease
LOFAKCML_01786 8.36e-154 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
LOFAKCML_01787 1e-119 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
LOFAKCML_01788 9.21e-161 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
LOFAKCML_01789 3.03e-10 - - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C-like protein
LOFAKCML_01790 2.01e-209 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LOFAKCML_01791 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
LOFAKCML_01792 0.0 - - - E - - - Amino acid permease
LOFAKCML_01794 1.51e-57 - - - - - - - -
LOFAKCML_01795 4.1e-67 - - - - - - - -
LOFAKCML_01796 3.71e-199 yitS - - S - - - EDD domain protein, DegV family
LOFAKCML_01797 2.57e-109 - - - K - - - Domain of unknown function (DUF1836)
LOFAKCML_01798 1.62e-57 - - - EGP - - - Major Facilitator Superfamily
LOFAKCML_01799 1.73e-44 - - - EGP - - - Major facilitator Superfamily
LOFAKCML_01800 2.32e-39 - - - S - - - GyrI-like small molecule binding domain
LOFAKCML_01801 2.62e-69 - - - S - - - GyrI-like small molecule binding domain
LOFAKCML_01802 1.06e-48 - - - - - - - -
LOFAKCML_01803 9.01e-137 - - - - - - - -
LOFAKCML_01804 1.18e-147 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
LOFAKCML_01805 1e-198 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
LOFAKCML_01806 2.52e-166 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
LOFAKCML_01807 1.17e-118 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
LOFAKCML_01808 7.69e-123 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase homologues.
LOFAKCML_01809 3.32e-53 - - - - - - - -
LOFAKCML_01810 0.0 - - - S - - - O-antigen ligase like membrane protein
LOFAKCML_01811 0.0 - - - S - - - SH3-like domain
LOFAKCML_01812 4.53e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LOFAKCML_01813 8.23e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
LOFAKCML_01814 1.27e-247 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
LOFAKCML_01815 2.09e-211 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
LOFAKCML_01816 1.76e-102 - - - - - - - -
LOFAKCML_01819 2.08e-68 - - - S - - - Psort location Cytoplasmic, score
LOFAKCML_01820 1.99e-172 mrr2 - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
LOFAKCML_01821 3.56e-280 - - - S - - - SLAP domain
LOFAKCML_01822 1.95e-45 - - - S - - - Enterocin A Immunity
LOFAKCML_01823 8.68e-46 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
LOFAKCML_01824 8.68e-44 - - - - - - - -
LOFAKCML_01825 3.26e-21 - - - - - - - -
LOFAKCML_01826 7.77e-36 - - - - - - - -
LOFAKCML_01827 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
LOFAKCML_01828 1.89e-83 - - - S - - - CAAX protease self-immunity
LOFAKCML_01829 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
LOFAKCML_01830 3.34e-286 yttB - - EGP - - - Major Facilitator
LOFAKCML_01831 8.61e-294 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
LOFAKCML_01832 5.57e-129 yitW - - S - - - Iron-sulfur cluster assembly protein
LOFAKCML_01833 1.35e-180 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LOFAKCML_01834 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
LOFAKCML_01836 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
LOFAKCML_01837 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LOFAKCML_01838 0.0 - - - S - - - Calcineurin-like phosphoesterase
LOFAKCML_01839 1.67e-105 - - - - - - - -
LOFAKCML_01840 4.43e-140 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
LOFAKCML_01841 4.13e-187 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LOFAKCML_01842 2.04e-164 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LOFAKCML_01843 2.82e-178 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LOFAKCML_01844 4.39e-198 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
LOFAKCML_01846 3.78e-112 usp5 - - T - - - universal stress protein
LOFAKCML_01847 8.38e-190 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
LOFAKCML_01848 4.74e-105 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LOFAKCML_01849 8.67e-111 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
LOFAKCML_01850 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
LOFAKCML_01851 3.08e-43 - - - - - - - -
LOFAKCML_01852 1.2e-201 - - - I - - - alpha/beta hydrolase fold
LOFAKCML_01853 1.35e-167 yibF - - S - - - overlaps another CDS with the same product name
LOFAKCML_01854 3.81e-255 yibE - - S - - - overlaps another CDS with the same product name
LOFAKCML_01855 6.11e-152 - - - - - - - -
LOFAKCML_01856 1.46e-264 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
LOFAKCML_01857 2.12e-292 - - - S - - - Cysteine-rich secretory protein family
LOFAKCML_01858 5.22e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LOFAKCML_01859 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
LOFAKCML_01860 3.27e-170 - - - - - - - -
LOFAKCML_01861 2.58e-155 - - - K - - - Bacterial regulatory proteins, tetR family
LOFAKCML_01862 6.88e-231 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LOFAKCML_01863 1.49e-71 - - - - - - - -
LOFAKCML_01864 3.43e-148 - - - GM - - - NmrA-like family
LOFAKCML_01865 2.62e-164 - - - S - - - Alpha/beta hydrolase family
LOFAKCML_01866 1.07e-203 epsV - - S - - - glycosyl transferase family 2
LOFAKCML_01867 1.56e-181 - - - S - - - Protein of unknown function (DUF1002)
LOFAKCML_01868 2.82e-185 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LOFAKCML_01869 1.09e-226 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LOFAKCML_01870 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LOFAKCML_01871 1.14e-111 - - - - - - - -
LOFAKCML_01872 1.98e-167 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
LOFAKCML_01873 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
LOFAKCML_01874 2.54e-214 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
LOFAKCML_01875 1.4e-179 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
LOFAKCML_01878 4.56e-166 - - - I - - - Acyl-transferase
LOFAKCML_01879 8.55e-184 arbx - - M - - - Glycosyl transferase family 8
LOFAKCML_01880 5.08e-237 - - - M - - - Glycosyl transferase family 8
LOFAKCML_01881 1.29e-208 - - - M - - - Glycosyl transferase family 8
LOFAKCML_01882 3.77e-213 arbZ - - I - - - Phosphate acyltransferases
LOFAKCML_01883 2.8e-123 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
LOFAKCML_01884 6.56e-40 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
LOFAKCML_01887 2.37e-271 - - - - - - - -
LOFAKCML_01888 1.49e-157 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
LOFAKCML_01889 4.14e-81 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
LOFAKCML_01890 2.89e-75 - - - - - - - -
LOFAKCML_01891 3.29e-87 - - - - - - - -
LOFAKCML_01892 3.53e-135 - - - S - - - Fic/DOC family
LOFAKCML_01893 7.88e-131 - - - - - - - -
LOFAKCML_01894 4.04e-265 - - - EGP - - - Major Facilitator Superfamily
LOFAKCML_01895 2.41e-263 - - - C - - - FAD binding domain
LOFAKCML_01896 1.51e-104 - - - K - - - LysR substrate binding domain
LOFAKCML_01897 2.79e-21 - - - V - - - Abi-like protein
LOFAKCML_01898 8.68e-41 - - - V - - - Abi-like protein
LOFAKCML_01900 8.26e-23 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
LOFAKCML_01901 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
LOFAKCML_01902 2.5e-121 - - - - - - - -
LOFAKCML_01903 1.05e-63 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
LOFAKCML_01904 7.38e-113 - - - S - - - Replication initiation factor
LOFAKCML_01905 1.24e-43 - - - - - - - -
LOFAKCML_01907 1.04e-153 - - - S ko:K07507 - ko00000,ko02000 MgtC family
LOFAKCML_01908 3.87e-303 - - - I - - - Protein of unknown function (DUF2974)
LOFAKCML_01909 5.32e-35 - - - S - - - Transglycosylase associated protein
LOFAKCML_01910 0.000255 - - - S - - - CsbD-like
LOFAKCML_01911 1.22e-37 bbsF_1 2.8.3.19 - C ko:K18702 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
LOFAKCML_01912 1.77e-200 bbsF_1 2.8.3.19 - C ko:K18702 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
LOFAKCML_01913 3.29e-132 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
LOFAKCML_01914 3.72e-27 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
LOFAKCML_01915 6.43e-82 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
LOFAKCML_01916 1.77e-09 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
LOFAKCML_01917 9.82e-55 - - - M - - - domain protein
LOFAKCML_01918 1.17e-06 - - - - - - - -
LOFAKCML_01919 1.43e-45 - 2.1.1.113 - L ko:K00590 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
LOFAKCML_01920 1.9e-11 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
LOFAKCML_01921 6.32e-264 - - - EGP - - - Major facilitator Superfamily
LOFAKCML_01922 3.23e-149 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
LOFAKCML_01923 0.0 - - - S - - - Uncharacterised protein family (UPF0236)
LOFAKCML_01924 5.67e-197 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LOFAKCML_01925 4.32e-315 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LOFAKCML_01926 9.11e-281 malE - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LOFAKCML_01927 1.41e-266 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LOFAKCML_01928 2.04e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
LOFAKCML_01929 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
LOFAKCML_01930 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
LOFAKCML_01931 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
LOFAKCML_01932 7.31e-161 ackA 2.7.2.1 - H ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LOFAKCML_01933 7.43e-229 yvdE - - K - - - helix_turn _helix lactose operon repressor
LOFAKCML_01934 4.51e-189 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
LOFAKCML_01935 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LOFAKCML_01936 4.68e-193 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LOFAKCML_01938 8.76e-80 - - - L - - - RelB antitoxin
LOFAKCML_01940 3.71e-169 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
LOFAKCML_01941 2.89e-51 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
LOFAKCML_01942 4.34e-239 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
LOFAKCML_01943 6.89e-97 - - - M - - - NlpC/P60 family
LOFAKCML_01944 7.78e-190 - - - EG - - - EamA-like transporter family
LOFAKCML_01945 2.01e-197 - - - EG - - - EamA-like transporter family
LOFAKCML_01946 9.7e-140 - - - - - - - -
LOFAKCML_01947 2.61e-100 - - - - - - - -
LOFAKCML_01948 1.84e-74 - - - S - - - DUF218 domain
LOFAKCML_01949 7.46e-125 - - - S - - - DUF218 domain
LOFAKCML_01950 3.09e-168 yheS_2 - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
LOFAKCML_01951 5.86e-39 yheS_2 - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
LOFAKCML_01952 2.58e-108 - - - - - - - -
LOFAKCML_01953 6.82e-74 - - - - - - - -
LOFAKCML_01954 2.19e-307 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LOFAKCML_01955 1.38e-313 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LOFAKCML_01956 9.51e-233 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LOFAKCML_01959 7.45e-258 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
LOFAKCML_01960 3.6e-242 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
LOFAKCML_01961 5.5e-301 - - - E - - - amino acid
LOFAKCML_01962 6.39e-177 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
LOFAKCML_01963 1.24e-312 yifK - - E ko:K03293 - ko00000 Amino acid permease
LOFAKCML_01964 4.16e-299 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
LOFAKCML_01965 3.65e-156 - - - - - - - -
LOFAKCML_01966 3.3e-151 sipS3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LOFAKCML_01967 5.62e-94 - - - M - - - Glycosyl transferase family 2
LOFAKCML_01968 1.91e-13 - - - M - - - Glycosyl transferases group 1
LOFAKCML_01969 5.84e-80 - - - M - - - Glycosyltransferase like family 2
LOFAKCML_01970 2.03e-100 - - - - - - - -
LOFAKCML_01971 3.39e-116 - - - - - - - -
LOFAKCML_01972 1.14e-23 - - - - - - - -
LOFAKCML_01973 3.42e-41 - - - S - - - Transglycosylase associated protein
LOFAKCML_01974 5.96e-106 asp1 - - S - - - Asp23 family, cell envelope-related function
LOFAKCML_01975 1.83e-33 - - - S - - - Small integral membrane protein (DUF2273)
LOFAKCML_01976 5.13e-119 - - - - - - - -
LOFAKCML_01977 3.69e-30 - - - K - - - DeoR C terminal sensor domain
LOFAKCML_01978 3.42e-12 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
LOFAKCML_01979 1.52e-54 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
LOFAKCML_01980 1.96e-225 - - - L - - - Belongs to the 'phage' integrase family
LOFAKCML_01981 2.94e-65 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain protein
LOFAKCML_01982 1.57e-275 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
LOFAKCML_01983 2.99e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
LOFAKCML_01984 1.59e-94 - - - L - - - Transposase and inactivated derivatives, IS30 family
LOFAKCML_01985 6.57e-97 - - - L - - - Transposase and inactivated derivatives, IS30 family
LOFAKCML_01989 1.44e-52 - - - K - - - LysR substrate binding domain
LOFAKCML_01990 5.52e-128 - - - K - - - LysR substrate binding domain
LOFAKCML_01991 1.09e-141 - - - K - - - Transcriptional regulator, LysR family
LOFAKCML_01992 2.02e-306 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
LOFAKCML_01994 3.3e-20 - - - - - - - -
LOFAKCML_01995 2.65e-75 - - - - - - - -
LOFAKCML_01996 1.31e-10 - - - - - - - -

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)