ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MNLEDHHB_00001 4.13e-56 - - - - - - - -
MNLEDHHB_00002 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MNLEDHHB_00003 1.99e-94 yecA - - K - - - Helix-turn-helix domain, rpiR family
MNLEDHHB_00004 2.68e-225 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MNLEDHHB_00005 3.46e-181 - - - GK - - - ROK family
MNLEDHHB_00006 1.8e-53 - - - L ko:K07497 - ko00000 hmm pf00665
MNLEDHHB_00007 1.23e-138 - - - L ko:K07497 - ko00000 hmm pf00665
MNLEDHHB_00008 4.4e-143 - - - L - - - Helix-turn-helix domain
MNLEDHHB_00009 3.69e-180 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MNLEDHHB_00010 4.06e-150 mgtC3 - - S ko:K07507 - ko00000,ko02000 MgtC family
MNLEDHHB_00011 1.89e-11 - - - C - - - FMN-dependent dehydrogenase
MNLEDHHB_00012 3.51e-30 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 beta-glucosidase activity
MNLEDHHB_00013 2.73e-204 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MNLEDHHB_00014 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MNLEDHHB_00015 2.07e-73 yheA - - S - - - Belongs to the UPF0342 family
MNLEDHHB_00016 3.37e-291 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
MNLEDHHB_00017 0.0 yhaN - - L - - - AAA domain
MNLEDHHB_00018 1.16e-241 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
MNLEDHHB_00019 3.03e-50 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
MNLEDHHB_00020 5.64e-200 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MNLEDHHB_00021 3.49e-56 - - - - - - - -
MNLEDHHB_00022 3.94e-103 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
MNLEDHHB_00023 6.86e-72 - - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
MNLEDHHB_00024 1.5e-173 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MNLEDHHB_00025 5.32e-268 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MNLEDHHB_00026 7.82e-161 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MNLEDHHB_00027 1.64e-72 ytpP - - CO - - - Thioredoxin
MNLEDHHB_00028 3.06e-157 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MNLEDHHB_00029 0.0 - - - S - - - SLAP domain
MNLEDHHB_00030 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MNLEDHHB_00031 1.13e-223 - - - S - - - SLAP domain
MNLEDHHB_00032 2.61e-76 - - - M - - - Peptidase family M1 domain
MNLEDHHB_00033 2.69e-178 - - - M - - - Peptidase family M1 domain
MNLEDHHB_00034 1.05e-47 - - - M - - - Peptidase family M1 domain
MNLEDHHB_00035 4.58e-248 - - - S - - - Bacteriocin helveticin-J
MNLEDHHB_00036 1.74e-28 - - - - - - - -
MNLEDHHB_00037 1.87e-68 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
MNLEDHHB_00038 9.65e-193 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
MNLEDHHB_00039 1.52e-158 - - - C - - - Flavodoxin
MNLEDHHB_00040 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
MNLEDHHB_00041 3.23e-103 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MNLEDHHB_00042 2.58e-274 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MNLEDHHB_00043 1.19e-170 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MNLEDHHB_00044 1.27e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MNLEDHHB_00045 1.56e-154 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MNLEDHHB_00046 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MNLEDHHB_00047 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MNLEDHHB_00048 1.26e-246 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MNLEDHHB_00049 1.78e-134 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MNLEDHHB_00050 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MNLEDHHB_00051 3.6e-304 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MNLEDHHB_00052 0.0 - - - L ko:K07012 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
MNLEDHHB_00053 2.61e-183 cas5 - - S ko:K19119 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas5)
MNLEDHHB_00054 0.0 csd1 - - M ko:K19117 - ko00000,ko02048 CRISPR-associated protein (Cas_Csd1)
MNLEDHHB_00055 1.3e-201 csd2 - - L ko:K19115,ko:K19118 - ko00000,ko02048 CRISPR-associated protein Cas7
MNLEDHHB_00056 2.83e-159 cas4 3.1.12.1 - L ko:K07464 - ko00000,ko01000,ko02048 Domain of unknown function DUF83
MNLEDHHB_00057 2.89e-251 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MNLEDHHB_00058 2.86e-39 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MNLEDHHB_00059 2.56e-19 - - - - - - - -
MNLEDHHB_00060 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MNLEDHHB_00061 2.52e-200 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MNLEDHHB_00062 9.85e-133 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MNLEDHHB_00063 5.46e-108 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MNLEDHHB_00064 6.19e-315 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
MNLEDHHB_00065 1.79e-213 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MNLEDHHB_00066 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MNLEDHHB_00068 1.39e-114 ydhF - - S - - - Aldo keto reductase
MNLEDHHB_00069 1e-24 ydhF - - S - - - Aldo keto reductase
MNLEDHHB_00070 5.89e-57 - - - - - - - -
MNLEDHHB_00071 1.11e-308 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Adenine deaminase C-terminal domain
MNLEDHHB_00072 2.47e-188 - - - P ko:K02055 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
MNLEDHHB_00073 3.67e-173 potA11 3.6.3.30 - P ko:K02010,ko:K02052 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MNLEDHHB_00074 3e-147 potC3 - - E ko:K02053 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MNLEDHHB_00075 2.17e-130 - - - E ko:K02054 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MNLEDHHB_00076 4.81e-60 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
MNLEDHHB_00077 1.15e-38 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
MNLEDHHB_00078 8.04e-72 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MNLEDHHB_00079 4.77e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MNLEDHHB_00080 1.02e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MNLEDHHB_00081 1.51e-121 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
MNLEDHHB_00082 4.77e-270 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
MNLEDHHB_00083 2.14e-154 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MNLEDHHB_00084 1.12e-141 yqeK - - H - - - Hydrolase, HD family
MNLEDHHB_00085 2.08e-77 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MNLEDHHB_00086 4.26e-271 ylbM - - S - - - Belongs to the UPF0348 family
MNLEDHHB_00087 8.27e-124 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
MNLEDHHB_00088 7.09e-163 csrR - - K - - - response regulator
MNLEDHHB_00089 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MNLEDHHB_00090 9.66e-110 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
MNLEDHHB_00091 4.08e-203 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MNLEDHHB_00092 9.28e-58 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MNLEDHHB_00093 3.01e-177 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MNLEDHHB_00094 1.4e-80 yodB - - K - - - Transcriptional regulator, HxlR family
MNLEDHHB_00095 1.75e-255 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MNLEDHHB_00096 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MNLEDHHB_00097 2.74e-89 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MNLEDHHB_00098 9.25e-217 ldh3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
MNLEDHHB_00099 1.96e-29 - - - S - - - Phage derived protein Gp49-like (DUF891)
MNLEDHHB_00100 1.18e-51 - - - K - - - Helix-turn-helix domain
MNLEDHHB_00101 3.22e-114 - - - K - - - Acetyltransferase (GNAT) domain
MNLEDHHB_00102 3.06e-85 - - - S - - - Protein of unknown function (DUF3021)
MNLEDHHB_00103 1.27e-99 - - - K - - - LytTr DNA-binding domain
MNLEDHHB_00104 1.42e-57 - - - - - - - -
MNLEDHHB_00105 1.06e-132 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
MNLEDHHB_00106 1.44e-31 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
MNLEDHHB_00107 1.54e-65 - - - - - - - -
MNLEDHHB_00108 3.37e-190 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
MNLEDHHB_00109 8.26e-290 - - - L ko:K07478 - ko00000 AAA C-terminal domain
MNLEDHHB_00110 7.55e-44 - - - - - - - -
MNLEDHHB_00111 4.04e-85 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
MNLEDHHB_00113 2.09e-79 kptA - - H ko:K07559 - ko00000,ko01000,ko03016 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
MNLEDHHB_00114 7.32e-49 - - - S - - - Abi-like protein
MNLEDHHB_00115 2.01e-14 - - - S - - - Abi-like protein
MNLEDHHB_00117 1.64e-93 - - - S ko:K07045 - ko00000 Amidohydrolase
MNLEDHHB_00118 2.3e-85 - - - S ko:K07045 - ko00000 Amidohydrolase
MNLEDHHB_00119 5.25e-27 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MNLEDHHB_00120 3.21e-73 - - - G - - - Antibiotic biosynthesis monooxygenase
MNLEDHHB_00121 4.17e-29 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
MNLEDHHB_00122 1.47e-91 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
MNLEDHHB_00123 3.8e-144 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
MNLEDHHB_00124 2.95e-139 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
MNLEDHHB_00125 2.39e-174 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MNLEDHHB_00126 1.71e-203 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MNLEDHHB_00127 6.63e-56 - - - S - - - Alpha beta hydrolase
MNLEDHHB_00128 3.61e-80 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
MNLEDHHB_00129 1.6e-74 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
MNLEDHHB_00130 5.69e-185 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
MNLEDHHB_00131 5.21e-41 - 1.1.1.3 - T ko:K00003,ko:K07166 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 phosphoserine phosphatase activity
MNLEDHHB_00132 6.66e-41 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
MNLEDHHB_00133 8.09e-44 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
MNLEDHHB_00134 3.49e-59 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
MNLEDHHB_00136 4.09e-43 - - - S - - - TraX protein
MNLEDHHB_00137 2.94e-74 - - - K - - - Bacterial regulatory proteins, tetR family
MNLEDHHB_00138 5.15e-23 - - - K - - - Bacterial regulatory proteins, tetR family
MNLEDHHB_00139 1.56e-198 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MNLEDHHB_00140 2.2e-139 - - - K - - - COG COG0846 NAD-dependent protein deacetylases, SIR2 family
MNLEDHHB_00141 2.65e-18 - - - K - - - COG COG0846 NAD-dependent protein deacetylases, SIR2 family
MNLEDHHB_00142 6.18e-120 - - - K - - - acetyltransferase
MNLEDHHB_00143 9.82e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MNLEDHHB_00144 1.64e-53 - - - - - - - -
MNLEDHHB_00145 2.05e-79 snf - - KL - - - domain protein
MNLEDHHB_00146 4.79e-252 snf - - KL - - - domain protein
MNLEDHHB_00147 2.8e-136 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MNLEDHHB_00148 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MNLEDHHB_00149 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MNLEDHHB_00150 1.42e-217 - - - K - - - Transcriptional regulator
MNLEDHHB_00151 3e-221 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
MNLEDHHB_00152 5.37e-143 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MNLEDHHB_00153 6.39e-73 - - - K - - - Helix-turn-helix domain
MNLEDHHB_00154 4.69e-71 - - - S - - - Protein of unknown function (DUF1275)
MNLEDHHB_00155 4.34e-48 - - - S - - - Transglycosylase associated protein
MNLEDHHB_00156 1.13e-71 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MNLEDHHB_00157 1.73e-19 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MNLEDHHB_00158 1.11e-35 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MNLEDHHB_00159 1.92e-140 XK27_00160 - - S - - - Domain of unknown function (DUF5052)
MNLEDHHB_00160 4.4e-67 flaR - - F - - - topology modulation protein
MNLEDHHB_00161 3.71e-95 - - - - - - - -
MNLEDHHB_00162 5.71e-262 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
MNLEDHHB_00163 3.43e-51 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MNLEDHHB_00164 8.96e-122 - - - - - - - -
MNLEDHHB_00170 1.22e-139 - - - K - - - Helix-turn-helix XRE-family like proteins
MNLEDHHB_00171 1.03e-223 - - - S - - - Uncharacterised protein family (UPF0236)
MNLEDHHB_00172 3.23e-36 - - - - - - - -
MNLEDHHB_00173 2.49e-189 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MNLEDHHB_00174 5.33e-119 - - - - - - - -
MNLEDHHB_00175 1.3e-41 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
MNLEDHHB_00177 8.45e-92 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
MNLEDHHB_00178 2.55e-246 pbpX1 - - V - - - Beta-lactamase
MNLEDHHB_00179 0.0 - - - L - - - Helicase C-terminal domain protein
MNLEDHHB_00180 2.49e-261 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
MNLEDHHB_00181 2.12e-43 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
MNLEDHHB_00182 1.25e-204 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MNLEDHHB_00183 3.77e-213 - - - G - - - Phosphotransferase enzyme family
MNLEDHHB_00184 6.49e-245 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MNLEDHHB_00185 5.85e-38 - - - - - - - -
MNLEDHHB_00186 4.99e-185 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 haloacid dehalogenase-like hydrolase
MNLEDHHB_00187 0.0 fusA1 - - J - - - elongation factor G
MNLEDHHB_00188 1.35e-204 yvgN - - C - - - Aldo keto reductase
MNLEDHHB_00190 5.5e-48 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MNLEDHHB_00191 1.49e-51 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MNLEDHHB_00192 1.1e-172 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MNLEDHHB_00193 6.21e-219 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MNLEDHHB_00194 3.05e-164 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MNLEDHHB_00195 4.93e-166 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MNLEDHHB_00196 3.14e-53 - - - - - - - -
MNLEDHHB_00197 4.97e-24 - - - - - - - -
MNLEDHHB_00198 1.08e-131 - - - E - - - GDSL-like Lipase/Acylhydrolase
MNLEDHHB_00199 3.31e-221 ydbI - - K - - - AI-2E family transporter
MNLEDHHB_00200 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
MNLEDHHB_00201 4.63e-78 - - - S - - - Domain of unknown function (DUF4430)
MNLEDHHB_00202 6.12e-112 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
MNLEDHHB_00203 8.95e-129 - - - S - - - Cob(I)alamin adenosyltransferase
MNLEDHHB_00204 2.5e-186 - - - S - - - Putative ABC-transporter type IV
MNLEDHHB_00205 1.73e-305 - - - S - - - LPXTG cell wall anchor motif
MNLEDHHB_00206 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MNLEDHHB_00207 0.0 - - - V - - - Restriction endonuclease
MNLEDHHB_00208 1.79e-63 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MNLEDHHB_00209 9.62e-58 - - - K - - - COG COG0846 NAD-dependent protein deacetylases, SIR2 family
MNLEDHHB_00210 3.8e-70 - - - K ko:K09705 - ko00000 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MNLEDHHB_00211 6.76e-168 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MNLEDHHB_00212 8.08e-147 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MNLEDHHB_00213 1.21e-40 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
MNLEDHHB_00216 2.58e-313 - 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MNLEDHHB_00217 4.38e-196 - - - L - - - Belongs to the 'phage' integrase family
MNLEDHHB_00219 1.33e-55 - - - O - - - RNA helicase
MNLEDHHB_00220 7.07e-18 - - - EP - - - Plasmid replication protein
MNLEDHHB_00223 2.45e-205 - - - D - - - COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MNLEDHHB_00226 4.8e-212 - - - EGP - - - Major facilitator Superfamily
MNLEDHHB_00227 1.96e-168 moeB 2.7.7.80, 2.8.1.11 - H ko:K21029,ko:K21147 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
MNLEDHHB_00228 4.28e-52 - - - S - - - ThiS family
MNLEDHHB_00230 1.76e-81 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MNLEDHHB_00231 3.87e-83 - - - V - - - Beta-lactamase
MNLEDHHB_00232 2.98e-63 - - - S - - - Protein of unknown function DUF262
MNLEDHHB_00233 1.32e-11 - - - - - - - -
MNLEDHHB_00234 4.03e-09 - - - - - - - -
MNLEDHHB_00235 4.48e-60 - - - S - - - Uncharacterised protein family (UPF0236)
MNLEDHHB_00236 3.46e-89 - - - L - - - An automated process has identified a potential problem with this gene model
MNLEDHHB_00237 7.38e-253 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MNLEDHHB_00238 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
MNLEDHHB_00239 6.82e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MNLEDHHB_00240 5.95e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MNLEDHHB_00241 1.64e-261 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MNLEDHHB_00242 1e-131 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MNLEDHHB_00243 1.1e-89 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
MNLEDHHB_00244 5.2e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MNLEDHHB_00245 1.06e-195 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MNLEDHHB_00246 5.59e-251 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MNLEDHHB_00247 6.25e-47 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MNLEDHHB_00248 2.06e-201 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MNLEDHHB_00249 4.01e-194 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
MNLEDHHB_00250 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MNLEDHHB_00251 2.46e-102 - - - S - - - ASCH
MNLEDHHB_00252 1.64e-142 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MNLEDHHB_00253 5.6e-45 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MNLEDHHB_00254 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MNLEDHHB_00255 1.6e-220 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MNLEDHHB_00256 2.87e-311 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MNLEDHHB_00257 3.17e-187 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MNLEDHHB_00258 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MNLEDHHB_00259 9.22e-213 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MNLEDHHB_00260 1.63e-148 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MNLEDHHB_00261 1.06e-159 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MNLEDHHB_00262 1.98e-64 - - - - - - - -
MNLEDHHB_00263 3.82e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MNLEDHHB_00264 1.67e-74 yloU - - S - - - Asp23 family, cell envelope-related function
MNLEDHHB_00265 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
MNLEDHHB_00266 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MNLEDHHB_00267 4.31e-232 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MNLEDHHB_00268 8.89e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MNLEDHHB_00269 2.11e-249 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MNLEDHHB_00270 3.41e-231 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MNLEDHHB_00271 7.39e-226 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MNLEDHHB_00272 6.36e-190 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MNLEDHHB_00273 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MNLEDHHB_00274 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MNLEDHHB_00275 1.56e-161 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MNLEDHHB_00276 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MNLEDHHB_00277 3.13e-230 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MNLEDHHB_00278 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MNLEDHHB_00279 1.63e-65 - - - - - - - -
MNLEDHHB_00280 3.86e-27 - - - K - - - DNA-binding transcription factor activity
MNLEDHHB_00281 3.07e-41 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
MNLEDHHB_00282 2.72e-42 - - - S - - - Protein of unknown function (DUF2929)
MNLEDHHB_00283 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MNLEDHHB_00284 3.62e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MNLEDHHB_00285 7.74e-47 - - - S - - - Lipopolysaccharide assembly protein A domain
MNLEDHHB_00286 1.13e-181 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MNLEDHHB_00287 3.02e-226 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MNLEDHHB_00288 0.0 oatA - - I - - - Acyltransferase
MNLEDHHB_00289 1.55e-308 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MNLEDHHB_00290 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MNLEDHHB_00291 1.82e-34 yngC - - S - - - SNARE associated Golgi protein
MNLEDHHB_00292 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
MNLEDHHB_00293 6.35e-173 gyaR 1.1.1.26, 1.1.1.399, 1.1.1.95 - CH ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MNLEDHHB_00294 2.84e-21 gyaR 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MNLEDHHB_00295 2.01e-178 yxeH - - S - - - hydrolase
MNLEDHHB_00296 5.47e-196 - - - S - - - reductase
MNLEDHHB_00297 1.24e-277 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MNLEDHHB_00298 4.34e-281 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MNLEDHHB_00299 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MNLEDHHB_00300 4.28e-312 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MNLEDHHB_00301 1.43e-96 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MNLEDHHB_00302 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MNLEDHHB_00303 4.44e-79 - - - - - - - -
MNLEDHHB_00304 7.07e-222 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
MNLEDHHB_00305 1.52e-114 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MNLEDHHB_00307 5.32e-26 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MNLEDHHB_00309 2.95e-33 - - - - ko:K14201 ko05150,map05150 ko00000,ko00001 -
MNLEDHHB_00310 1.42e-123 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
MNLEDHHB_00311 1.38e-309 - - - S - - - Putative threonine/serine exporter
MNLEDHHB_00312 2.82e-214 citR - - K - - - Putative sugar-binding domain
MNLEDHHB_00313 7.12e-69 - - - - - - - -
MNLEDHHB_00314 1.11e-84 - - - S - - - Domain of unknown function DUF1828
MNLEDHHB_00315 1.8e-123 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
MNLEDHHB_00316 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MNLEDHHB_00317 4.46e-190 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
MNLEDHHB_00318 1.01e-24 - - - - - - - -
MNLEDHHB_00319 4.16e-92 ytwI - - S - - - Protein of unknown function (DUF441)
MNLEDHHB_00320 1.23e-259 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MNLEDHHB_00321 6.49e-18 - - - S - - - SLAP domain
MNLEDHHB_00322 4.48e-109 - - - S - - - SLAP domain
MNLEDHHB_00323 1.2e-45 - - - L - - - An automated process has identified a potential problem with this gene model
MNLEDHHB_00324 1.21e-89 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MNLEDHHB_00325 2.86e-118 levB 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MNLEDHHB_00326 2.02e-33 levC - - M ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MNLEDHHB_00327 2.58e-139 levC - - M ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MNLEDHHB_00328 4.31e-194 levD - - G ko:K02771 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MNLEDHHB_00329 5.78e-63 - - - - - - - -
MNLEDHHB_00330 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MNLEDHHB_00331 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MNLEDHHB_00332 1.47e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MNLEDHHB_00333 4.87e-236 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MNLEDHHB_00334 1.42e-76 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MNLEDHHB_00335 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MNLEDHHB_00336 1.13e-270 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MNLEDHHB_00337 1.1e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
MNLEDHHB_00338 3.03e-311 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MNLEDHHB_00339 1.05e-82 - - - - - - - -
MNLEDHHB_00340 3.56e-102 - - - - - - - -
MNLEDHHB_00341 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MNLEDHHB_00342 5.32e-57 yrzL - - S - - - Belongs to the UPF0297 family
MNLEDHHB_00343 2.69e-95 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MNLEDHHB_00344 1.67e-66 yrzB - - S - - - Belongs to the UPF0473 family
MNLEDHHB_00345 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MNLEDHHB_00346 2.19e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MNLEDHHB_00347 5.38e-63 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MNLEDHHB_00348 3.63e-91 yslB - - S - - - Protein of unknown function (DUF2507)
MNLEDHHB_00349 3.27e-187 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MNLEDHHB_00350 2.16e-148 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MNLEDHHB_00351 1.05e-191 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
MNLEDHHB_00352 1.09e-28 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MNLEDHHB_00353 2.07e-65 - - - - - - - -
MNLEDHHB_00354 1.67e-274 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MNLEDHHB_00355 1.68e-229 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MNLEDHHB_00356 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MNLEDHHB_00357 2.42e-74 - - - - - - - -
MNLEDHHB_00358 0.0 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MNLEDHHB_00359 5.15e-127 yutD - - S - - - Protein of unknown function (DUF1027)
MNLEDHHB_00360 1.24e-187 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MNLEDHHB_00361 1.44e-110 - - - S - - - Protein of unknown function (DUF1461)
MNLEDHHB_00362 5.67e-149 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
MNLEDHHB_00363 2.16e-192 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MNLEDHHB_00364 2.03e-11 - - - S - - - Uncharacterised protein family (UPF0236)
MNLEDHHB_00365 7.69e-114 - - - S - - - Bacterial membrane protein, YfhO
MNLEDHHB_00366 3.99e-32 - - - - ko:K19167 - ko00000,ko02048 -
MNLEDHHB_00367 1.46e-81 - - - - ko:K19167 - ko00000,ko02048 -
MNLEDHHB_00368 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MNLEDHHB_00369 1.25e-302 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MNLEDHHB_00370 1.76e-161 - - - S - - - Haloacid dehalogenase-like hydrolase
MNLEDHHB_00371 3.32e-148 radC - - L ko:K03630 - ko00000 DNA repair protein
MNLEDHHB_00372 8.26e-226 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
MNLEDHHB_00373 8.27e-189 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MNLEDHHB_00374 1.97e-124 mreD - - - ko:K03571 - ko00000,ko03036 -
MNLEDHHB_00375 1.09e-18 - - - S - - - Protein of unknown function (DUF4044)
MNLEDHHB_00376 8.66e-70 - - - S - - - Protein of unknown function (DUF3397)
MNLEDHHB_00377 8.25e-79 - - - L - - - PFAM transposase, IS4 family protein
MNLEDHHB_00378 6.2e-53 - - - L - - - PFAM transposase, IS4 family protein
MNLEDHHB_00379 4.52e-62 - - - L - - - PFAM transposase, IS4 family protein
MNLEDHHB_00380 1.55e-99 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MNLEDHHB_00381 6.63e-232 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MNLEDHHB_00382 2.2e-70 ftsL - - D - - - Cell division protein FtsL
MNLEDHHB_00383 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MNLEDHHB_00384 5.4e-225 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MNLEDHHB_00385 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MNLEDHHB_00386 2.44e-267 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MNLEDHHB_00387 2.83e-181 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MNLEDHHB_00388 4.95e-305 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MNLEDHHB_00389 5.53e-262 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MNLEDHHB_00390 1.04e-94 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MNLEDHHB_00391 5.07e-62 yggT - - S ko:K02221 - ko00000,ko02044 YGGT family
MNLEDHHB_00392 9.06e-189 ylmH - - S - - - S4 domain protein
MNLEDHHB_00393 2.38e-163 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
MNLEDHHB_00394 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MNLEDHHB_00395 1.15e-43 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
MNLEDHHB_00396 3.64e-134 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MNLEDHHB_00397 2.13e-55 - - - - - - - -
MNLEDHHB_00398 2.8e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MNLEDHHB_00399 2.57e-273 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MNLEDHHB_00400 2.01e-74 XK27_04120 - - S - - - Putative amino acid metabolism
MNLEDHHB_00401 3.28e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MNLEDHHB_00402 4.34e-159 pgm - - G - - - Phosphoglycerate mutase family
MNLEDHHB_00403 1.82e-144 - - - S - - - repeat protein
MNLEDHHB_00404 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MNLEDHHB_00405 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MNLEDHHB_00406 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MNLEDHHB_00407 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MNLEDHHB_00408 7.84e-106 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MNLEDHHB_00412 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MNLEDHHB_00413 5.82e-250 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MNLEDHHB_00414 5.97e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MNLEDHHB_00415 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MNLEDHHB_00416 2.32e-305 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MNLEDHHB_00417 3.8e-80 - - - J ko:K07571 - ko00000 S1 RNA binding domain
MNLEDHHB_00418 6.18e-77 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MNLEDHHB_00419 1.26e-46 yabO - - J - - - S4 domain protein
MNLEDHHB_00420 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MNLEDHHB_00421 2.68e-134 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MNLEDHHB_00422 3.42e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MNLEDHHB_00423 8.34e-165 - - - S - - - (CBS) domain
MNLEDHHB_00424 5.52e-120 - - - K - - - transcriptional regulator
MNLEDHHB_00425 8.96e-274 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MNLEDHHB_00426 1.33e-79 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MNLEDHHB_00427 8.26e-317 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MNLEDHHB_00428 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MNLEDHHB_00429 5.28e-53 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MNLEDHHB_00430 6.65e-196 yhaX - - S - - - Sucrose-6F-phosphate phosphohydrolase
MNLEDHHB_00431 0.0 - - - E - - - amino acid
MNLEDHHB_00432 1.6e-287 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MNLEDHHB_00433 3.04e-180 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MNLEDHHB_00434 5.7e-194 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
MNLEDHHB_00435 3.02e-86 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
MNLEDHHB_00436 5.44e-116 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MNLEDHHB_00438 0.0 qacA - - EGP - - - Major Facilitator
MNLEDHHB_00439 2.3e-275 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
MNLEDHHB_00440 3.16e-150 pepA - - E - - - M42 glutamyl aminopeptidase
MNLEDHHB_00441 3.26e-101 pepA - - E - - - M42 glutamyl aminopeptidase
MNLEDHHB_00442 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
MNLEDHHB_00443 1.99e-41 - - - - - - - -
MNLEDHHB_00444 1.87e-116 - - - - - - - -
MNLEDHHB_00445 2.62e-166 - - - F - - - glutamine amidotransferase
MNLEDHHB_00446 1.23e-189 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MNLEDHHB_00447 1.25e-104 - - - K - - - Transcriptional regulator, MarR family
MNLEDHHB_00448 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MNLEDHHB_00449 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
MNLEDHHB_00450 1.79e-131 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MNLEDHHB_00451 2.1e-219 - - - EGP - - - Major facilitator superfamily
MNLEDHHB_00452 4.85e-145 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
MNLEDHHB_00453 1.46e-285 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
MNLEDHHB_00454 8.97e-170 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MNLEDHHB_00455 9.06e-192 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MNLEDHHB_00456 3.66e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MNLEDHHB_00457 1.66e-137 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MNLEDHHB_00458 3.99e-190 - - - S - - - Protein of unknown function (DUF2974)
MNLEDHHB_00459 2.36e-146 - - - S - - - SLAP domain
MNLEDHHB_00460 3.92e-306 srrA1 - - G ko:K02027,ko:K17244 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MNLEDHHB_00461 5.13e-209 - - - C - - - Domain of unknown function (DUF4931)
MNLEDHHB_00463 4.52e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MNLEDHHB_00464 3.83e-163 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MNLEDHHB_00465 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MNLEDHHB_00466 2.03e-222 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
MNLEDHHB_00467 7.43e-171 gntR - - K - - - UbiC transcription regulator-associated domain protein
MNLEDHHB_00468 5.69e-195 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MNLEDHHB_00469 2.57e-25 ybcH - - D ko:K06889 - ko00000 Alpha beta
MNLEDHHB_00470 1.62e-62 - - - - - - - -
MNLEDHHB_00471 4.46e-275 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
MNLEDHHB_00472 1.27e-273 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
MNLEDHHB_00473 2.38e-274 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MNLEDHHB_00474 1.72e-214 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MNLEDHHB_00475 3.93e-199 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MNLEDHHB_00476 4.23e-212 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
MNLEDHHB_00477 5.77e-102 ykuP - - C ko:K03839 - ko00000 Flavodoxin
MNLEDHHB_00478 5.01e-118 gtcA1 - - S - - - Teichoic acid glycosylation protein
MNLEDHHB_00479 3.14e-276 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MNLEDHHB_00480 5.82e-35 - - - - - - - -
MNLEDHHB_00482 1.5e-310 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MNLEDHHB_00483 5.51e-267 yfmL - - L - - - DEAD DEAH box helicase
MNLEDHHB_00484 6.35e-164 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MNLEDHHB_00485 2.75e-287 - - - E ko:K03294 - ko00000 amino acid
MNLEDHHB_00486 2.46e-132 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MNLEDHHB_00487 1.29e-312 yhdP - - S - - - Transporter associated domain
MNLEDHHB_00488 1.57e-35 - - - C - - - nitroreductase
MNLEDHHB_00489 2.85e-23 - - - C - - - nitroreductase
MNLEDHHB_00490 2.89e-52 - - - - - - - -
MNLEDHHB_00491 9.32e-112 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MNLEDHHB_00492 1.06e-94 - - - - - - - -
MNLEDHHB_00493 3.43e-184 glvR - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
MNLEDHHB_00494 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MNLEDHHB_00495 2.23e-110 - - - S - - - hydrolase
MNLEDHHB_00496 7.38e-20 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MNLEDHHB_00497 1.59e-206 - - - S - - - Phospholipase, patatin family
MNLEDHHB_00498 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MNLEDHHB_00499 1.86e-172 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MNLEDHHB_00500 5.69e-74 - - - S - - - Enterocin A Immunity
MNLEDHHB_00501 1.51e-73 yitW - - S - - - Iron-sulfur cluster assembly protein
MNLEDHHB_00502 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
MNLEDHHB_00503 1.07e-104 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
MNLEDHHB_00504 6.39e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MNLEDHHB_00505 4.53e-301 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
MNLEDHHB_00506 2.13e-186 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
MNLEDHHB_00507 1.6e-170 - - - - - - - -
MNLEDHHB_00508 1.57e-171 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MNLEDHHB_00509 5.75e-141 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MNLEDHHB_00510 8.95e-129 - - - G - - - Aldose 1-epimerase
MNLEDHHB_00511 8.94e-252 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MNLEDHHB_00512 6.93e-140 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MNLEDHHB_00513 0.0 XK27_08315 - - M - - - Sulfatase
MNLEDHHB_00514 0.0 - - - S - - - Fibronectin type III domain
MNLEDHHB_00515 3.63e-309 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MNLEDHHB_00516 3.27e-71 - - - - - - - -
MNLEDHHB_00518 0.0 pepC1 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
MNLEDHHB_00519 2.6e-148 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MNLEDHHB_00520 6.97e-264 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MNLEDHHB_00521 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
MNLEDHHB_00522 1.58e-82 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MNLEDHHB_00523 9.44e-99 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MNLEDHHB_00524 6.33e-148 - - - - - - - -
MNLEDHHB_00526 1.79e-148 - - - E - - - Belongs to the SOS response-associated peptidase family
MNLEDHHB_00527 2.86e-245 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MNLEDHHB_00528 5.22e-117 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
MNLEDHHB_00529 2.26e-138 - - - S ko:K06872 - ko00000 TPM domain
MNLEDHHB_00530 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
MNLEDHHB_00531 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MNLEDHHB_00532 1.91e-189 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
MNLEDHHB_00533 5.17e-129 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MNLEDHHB_00534 1.15e-205 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MNLEDHHB_00535 3.8e-51 veg - - S - - - Biofilm formation stimulator VEG
MNLEDHHB_00536 8.69e-192 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MNLEDHHB_00537 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MNLEDHHB_00538 7.63e-100 - - - S - - - SLAP domain
MNLEDHHB_00539 7.64e-62 - - - - - - - -
MNLEDHHB_00540 1.49e-226 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MNLEDHHB_00541 8.25e-169 - - - K - - - Protein of unknown function (DUF4065)
MNLEDHHB_00542 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
MNLEDHHB_00543 1.77e-262 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
MNLEDHHB_00544 1.71e-265 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MNLEDHHB_00545 2.94e-50 - - - - - - - -
MNLEDHHB_00547 7.36e-240 - - - S - - - SLAP domain
MNLEDHHB_00548 4.3e-49 - - - S - - - Protein of unknown function (DUF2922)
MNLEDHHB_00549 7.02e-40 - - - - - - - -
MNLEDHHB_00550 8.86e-09 - - - - - - - -
MNLEDHHB_00552 1.63e-112 - - - - - - - -
MNLEDHHB_00553 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MNLEDHHB_00554 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MNLEDHHB_00555 9.99e-288 yttB - - EGP - - - Major Facilitator
MNLEDHHB_00556 8.61e-294 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
MNLEDHHB_00557 5.57e-129 yitW - - S - - - Iron-sulfur cluster assembly protein
MNLEDHHB_00558 1.35e-180 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MNLEDHHB_00559 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
MNLEDHHB_00561 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
MNLEDHHB_00562 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MNLEDHHB_00563 0.0 - - - S - - - Calcineurin-like phosphoesterase
MNLEDHHB_00564 4.98e-107 - - - - - - - -
MNLEDHHB_00565 4.43e-140 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MNLEDHHB_00566 4.13e-187 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MNLEDHHB_00567 2.04e-164 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MNLEDHHB_00568 1.63e-177 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MNLEDHHB_00569 4.39e-198 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
MNLEDHHB_00571 3.78e-112 usp5 - - T - - - universal stress protein
MNLEDHHB_00572 3.98e-188 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MNLEDHHB_00573 3.1e-112 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MNLEDHHB_00574 8.67e-111 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
MNLEDHHB_00575 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
MNLEDHHB_00576 3.08e-43 - - - - - - - -
MNLEDHHB_00577 5.96e-202 - - - I - - - alpha/beta hydrolase fold
MNLEDHHB_00578 1.35e-167 yibF - - S - - - overlaps another CDS with the same product name
MNLEDHHB_00579 3.81e-255 yibE - - S - - - overlaps another CDS with the same product name
MNLEDHHB_00580 6.11e-152 - - - - - - - -
MNLEDHHB_00581 1.46e-264 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MNLEDHHB_00582 2.12e-292 - - - S - - - Cysteine-rich secretory protein family
MNLEDHHB_00583 5.22e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MNLEDHHB_00584 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MNLEDHHB_00585 3.27e-170 - - - - - - - -
MNLEDHHB_00586 2.58e-155 - - - K - - - Bacterial regulatory proteins, tetR family
MNLEDHHB_00587 1.97e-230 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MNLEDHHB_00588 8.64e-71 - - - - - - - -
MNLEDHHB_00589 3.43e-148 - - - GM - - - NmrA-like family
MNLEDHHB_00590 2.62e-164 - - - S - - - Alpha/beta hydrolase family
MNLEDHHB_00591 1.07e-203 epsV - - S - - - glycosyl transferase family 2
MNLEDHHB_00592 4.69e-183 - - - S - - - Protein of unknown function (DUF1002)
MNLEDHHB_00593 8.08e-185 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MNLEDHHB_00594 1.09e-226 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MNLEDHHB_00595 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MNLEDHHB_00596 1.14e-111 - - - - - - - -
MNLEDHHB_00597 1.39e-167 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
MNLEDHHB_00598 1.48e-49 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
MNLEDHHB_00599 1.87e-158 terC - - P - - - Integral membrane protein TerC family
MNLEDHHB_00600 2.78e-82 yeaO - - S - - - Protein of unknown function, DUF488
MNLEDHHB_00601 1.47e-157 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MNLEDHHB_00602 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MNLEDHHB_00603 4.11e-173 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MNLEDHHB_00604 3.72e-201 - - - L - - - HNH nucleases
MNLEDHHB_00605 2.94e-155 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
MNLEDHHB_00606 4.37e-191 - - - G - - - Glycosyl hydrolases family 8
MNLEDHHB_00607 2.09e-286 ydaM - - M - - - Glycosyl transferase family group 2
MNLEDHHB_00608 3.56e-180 - - - - - - - -
MNLEDHHB_00609 9.69e-25 - - - - - - - -
MNLEDHHB_00610 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MNLEDHHB_00611 3.98e-234 eriC - - P ko:K03281 - ko00000 chloride
MNLEDHHB_00612 3.04e-50 - - - GK - - - ROK family
MNLEDHHB_00613 7.27e-52 - - - I - - - Carboxylesterase family
MNLEDHHB_00614 4.9e-98 - - - I - - - Carboxylesterase family
MNLEDHHB_00615 7.57e-133 - - - GM - - - NmrA-like family
MNLEDHHB_00616 1.14e-41 - - - S ko:K18918 - ko00000,ko02048,ko03000 RelB antitoxin
MNLEDHHB_00617 2.15e-144 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MNLEDHHB_00618 1.32e-156 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MNLEDHHB_00619 1.7e-209 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MNLEDHHB_00620 5.63e-120 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MNLEDHHB_00621 1.1e-231 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MNLEDHHB_00622 5.76e-304 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MNLEDHHB_00623 1.3e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MNLEDHHB_00624 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MNLEDHHB_00625 6.03e-42 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MNLEDHHB_00626 3.46e-10 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MNLEDHHB_00627 4.69e-77 - - - - - - - -
MNLEDHHB_00629 1.07e-177 - - - U ko:K05340 - ko00000,ko02000 sugar transport
MNLEDHHB_00630 1.06e-62 - - - - - - - -
MNLEDHHB_00631 2.21e-100 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MNLEDHHB_00632 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MNLEDHHB_00633 1.66e-79 - - - S - - - Bacterial PH domain
MNLEDHHB_00634 7.87e-37 - - - - - - - -
MNLEDHHB_00635 1.55e-87 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
MNLEDHHB_00636 1.44e-226 lipA - - I - - - Carboxylesterase family
MNLEDHHB_00638 1.83e-264 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MNLEDHHB_00639 0.0 - - - S - - - Predicted membrane protein (DUF2207)
MNLEDHHB_00640 4.18e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
MNLEDHHB_00641 1.01e-161 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MNLEDHHB_00642 7.18e-193 supH - - S - - - haloacid dehalogenase-like hydrolase
MNLEDHHB_00643 0.0 ycaM - - E - - - amino acid
MNLEDHHB_00644 1.22e-122 - - - - - - - -
MNLEDHHB_00645 1.73e-96 - - - - - - - -
MNLEDHHB_00647 6.71e-241 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
MNLEDHHB_00648 1.16e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MNLEDHHB_00649 6.01e-288 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MNLEDHHB_00650 2.71e-183 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MNLEDHHB_00651 3.58e-124 - - - - - - - -
MNLEDHHB_00652 1.15e-200 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
MNLEDHHB_00653 7.79e-173 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MNLEDHHB_00654 5.23e-231 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
MNLEDHHB_00655 1.87e-118 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
MNLEDHHB_00656 7.47e-128 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MNLEDHHB_00657 1.71e-209 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
MNLEDHHB_00658 9.1e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MNLEDHHB_00659 5.95e-176 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MNLEDHHB_00660 3.09e-178 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MNLEDHHB_00661 1.29e-261 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MNLEDHHB_00662 1.44e-192 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MNLEDHHB_00663 2.51e-216 ybbR - - S - - - YbbR-like protein
MNLEDHHB_00664 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MNLEDHHB_00665 5.9e-192 - - - S - - - hydrolase
MNLEDHHB_00666 8.04e-190 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MNLEDHHB_00667 3.74e-153 - - - - - - - -
MNLEDHHB_00668 2.06e-112 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MNLEDHHB_00669 3.38e-273 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MNLEDHHB_00670 2.01e-185 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MNLEDHHB_00671 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MNLEDHHB_00672 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MNLEDHHB_00673 8.42e-236 ybcH - - D ko:K06889 - ko00000 Alpha beta
MNLEDHHB_00674 1.38e-225 degV1 - - S - - - DegV family
MNLEDHHB_00675 6.65e-208 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
MNLEDHHB_00676 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MNLEDHHB_00677 3.87e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MNLEDHHB_00678 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MNLEDHHB_00679 1.78e-42 - - - S - - - SLAP domain
MNLEDHHB_00680 1.89e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MNLEDHHB_00681 9.77e-108 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MNLEDHHB_00682 1.93e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MNLEDHHB_00683 1.02e-79 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MNLEDHHB_00684 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MNLEDHHB_00685 2.09e-267 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MNLEDHHB_00686 4.08e-47 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
MNLEDHHB_00687 4.11e-254 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MNLEDHHB_00688 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MNLEDHHB_00689 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
MNLEDHHB_00690 1.31e-81 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MNLEDHHB_00691 5.11e-187 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MNLEDHHB_00692 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MNLEDHHB_00693 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MNLEDHHB_00694 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MNLEDHHB_00695 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MNLEDHHB_00696 0.0 eriC - - P ko:K03281 - ko00000 chloride
MNLEDHHB_00697 8.82e-265 - - - - - - - -
MNLEDHHB_00698 6.46e-27 - - - - - - - -
MNLEDHHB_00699 2.58e-89 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
MNLEDHHB_00700 2.11e-93 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
MNLEDHHB_00701 1.52e-238 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MNLEDHHB_00702 2.99e-180 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
MNLEDHHB_00703 3.37e-220 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
MNLEDHHB_00704 9.25e-82 - - - S - - - Domain of unknown function (DUF956)
MNLEDHHB_00705 2.49e-47 - - - K - - - Transcriptional regulator
MNLEDHHB_00706 5.02e-60 - - - K - - - Transcriptional regulator
MNLEDHHB_00707 2.2e-109 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
MNLEDHHB_00708 6.69e-301 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MNLEDHHB_00709 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MNLEDHHB_00710 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MNLEDHHB_00711 1.66e-61 - - - - - - - -
MNLEDHHB_00712 5.03e-128 - - - E - - - amino acid
MNLEDHHB_00713 3.3e-55 - - - - - - - -
MNLEDHHB_00714 8.11e-108 - - - M - - - LPXTG-motif cell wall anchor domain protein
MNLEDHHB_00715 2.86e-41 - - - S - - - LPXTG cell wall anchor motif
MNLEDHHB_00716 2.15e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MNLEDHHB_00717 1.75e-137 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MNLEDHHB_00718 1.85e-48 - - - - - - - -
MNLEDHHB_00719 1.77e-93 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
MNLEDHHB_00720 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
MNLEDHHB_00721 0.0 - - - S - - - TerB-C domain
MNLEDHHB_00722 0.0 - - - P - - - P-loop Domain of unknown function (DUF2791)
MNLEDHHB_00723 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
MNLEDHHB_00724 4.75e-80 - - - - - - - -
MNLEDHHB_00725 1.62e-178 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
MNLEDHHB_00726 4.49e-50 - - - S - - - PD-(D/E)XK nuclease family transposase
MNLEDHHB_00729 1.18e-165 - - - K ko:K03710 - ko00000,ko03000 UTRA
MNLEDHHB_00730 2.85e-290 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MNLEDHHB_00731 2.2e-180 - - - S - - - Peptidase_C39 like family
MNLEDHHB_00732 7.46e-125 - - - S - - - DUF218 domain
MNLEDHHB_00733 1.84e-74 - - - S - - - DUF218 domain
MNLEDHHB_00734 6.41e-101 - - - - - - - -
MNLEDHHB_00735 2.38e-140 - - - - - - - -
MNLEDHHB_00736 2.01e-197 - - - EG - - - EamA-like transporter family
MNLEDHHB_00737 1.83e-188 - - - EG - - - EamA-like transporter family
MNLEDHHB_00738 1.19e-97 - - - M - - - NlpC/P60 family
MNLEDHHB_00739 0.0 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
MNLEDHHB_00740 5.27e-169 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
MNLEDHHB_00742 8.76e-80 - - - L - - - RelB antitoxin
MNLEDHHB_00744 8.09e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MNLEDHHB_00745 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MNLEDHHB_00746 1.57e-189 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MNLEDHHB_00747 1.68e-225 yvdE - - K - - - helix_turn _helix lactose operon repressor
MNLEDHHB_00748 7.31e-161 ackA 2.7.2.1 - H ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MNLEDHHB_00749 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
MNLEDHHB_00750 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MNLEDHHB_00751 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MNLEDHHB_00752 2.04e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
MNLEDHHB_00753 1.41e-266 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MNLEDHHB_00754 9.11e-281 malE - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MNLEDHHB_00755 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MNLEDHHB_00756 1.39e-197 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MNLEDHHB_00757 9.3e-56 ymdB - - S - - - Macro domain protein
MNLEDHHB_00758 2.85e-37 tnpR - - L - - - Resolvase, N terminal domain
MNLEDHHB_00759 7.6e-121 - - - - - - - -
MNLEDHHB_00760 1.83e-33 - - - S - - - Small integral membrane protein (DUF2273)
MNLEDHHB_00761 5.96e-106 asp1 - - S - - - Asp23 family, cell envelope-related function
MNLEDHHB_00762 3.42e-41 - - - S - - - Transglycosylase associated protein
MNLEDHHB_00763 1.14e-23 - - - - - - - -
MNLEDHHB_00764 2.91e-99 M1-431 - - S - - - Protein of unknown function (DUF1706)
MNLEDHHB_00765 3.55e-149 - - - - - - - -
MNLEDHHB_00766 2.08e-11 - - - - - - - -
MNLEDHHB_00767 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
MNLEDHHB_00768 2.18e-215 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
MNLEDHHB_00769 2.27e-59 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
MNLEDHHB_00770 2.65e-246 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MNLEDHHB_00771 2.95e-197 - - - I - - - Alpha/beta hydrolase family
MNLEDHHB_00772 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MNLEDHHB_00773 0.0 pepC4 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MNLEDHHB_00774 1.62e-63 - - - - - - - -
MNLEDHHB_00775 1.95e-70 - - - - - - - -
MNLEDHHB_00776 8.82e-80 - - - M - - - Rib/alpha-like repeat
MNLEDHHB_00777 7.82e-211 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MNLEDHHB_00779 4.67e-105 - - - M - - - domain protein
MNLEDHHB_00780 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MNLEDHHB_00781 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MNLEDHHB_00782 5.03e-38 - - - - - - - -
MNLEDHHB_00783 4.88e-131 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MNLEDHHB_00784 1.46e-240 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MNLEDHHB_00785 3.21e-208 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MNLEDHHB_00786 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
MNLEDHHB_00787 2.08e-21 ps301 - - K - - - sequence-specific DNA binding
MNLEDHHB_00788 3.86e-186 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MNLEDHHB_00789 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MNLEDHHB_00790 2.54e-267 - - - T - - - His Kinase A (phosphoacceptor) domain
MNLEDHHB_00791 1.18e-156 vanR - - K - - - response regulator
MNLEDHHB_00792 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
MNLEDHHB_00793 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
MNLEDHHB_00794 2.2e-177 - - - S - - - Protein of unknown function (DUF1129)
MNLEDHHB_00795 4.85e-257 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MNLEDHHB_00796 1.83e-58 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
MNLEDHHB_00797 3.96e-197 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MNLEDHHB_00798 2.77e-175 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
MNLEDHHB_00799 3.14e-191 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MNLEDHHB_00800 9.37e-169 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
MNLEDHHB_00801 2.12e-114 cvpA - - S - - - Colicin V production protein
MNLEDHHB_00802 2.31e-229 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MNLEDHHB_00803 4.51e-192 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MNLEDHHB_00804 1.05e-125 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MNLEDHHB_00805 4.65e-123 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MNLEDHHB_00806 6.8e-140 - - - K - - - WHG domain
MNLEDHHB_00807 4.74e-51 - - - - - - - -
MNLEDHHB_00808 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MNLEDHHB_00809 3.81e-151 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MNLEDHHB_00810 1.12e-228 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MNLEDHHB_00811 1.7e-123 - - - K - - - Bacterial regulatory proteins, tetR family
MNLEDHHB_00812 9.98e-144 - - - G - - - phosphoglycerate mutase
MNLEDHHB_00813 1.14e-179 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
MNLEDHHB_00814 6.89e-182 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
MNLEDHHB_00815 3.18e-154 - - - - - - - -
MNLEDHHB_00816 4.46e-100 - - - C - - - Domain of unknown function (DUF4931)
MNLEDHHB_00817 6.34e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MNLEDHHB_00818 3.29e-146 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MNLEDHHB_00819 2.23e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MNLEDHHB_00820 3.16e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MNLEDHHB_00821 1.91e-196 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MNLEDHHB_00822 2.94e-60 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MNLEDHHB_00823 9.07e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MNLEDHHB_00824 3.03e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MNLEDHHB_00825 1.66e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MNLEDHHB_00826 1.45e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MNLEDHHB_00827 4.48e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MNLEDHHB_00828 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MNLEDHHB_00829 6.92e-45 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MNLEDHHB_00830 2.9e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MNLEDHHB_00831 1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MNLEDHHB_00832 2.28e-89 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MNLEDHHB_00833 5.05e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MNLEDHHB_00834 7.4e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MNLEDHHB_00835 2.63e-110 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MNLEDHHB_00836 2.22e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MNLEDHHB_00837 1.73e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MNLEDHHB_00838 7.24e-301 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MNLEDHHB_00839 2.61e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MNLEDHHB_00840 1.28e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MNLEDHHB_00841 1.89e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MNLEDHHB_00842 1.46e-73 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MNLEDHHB_00843 3.82e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MNLEDHHB_00844 1.8e-218 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MNLEDHHB_00845 3.16e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MNLEDHHB_00846 2.37e-179 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MNLEDHHB_00847 1.45e-190 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MNLEDHHB_00848 5.22e-179 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MNLEDHHB_00849 3.02e-183 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MNLEDHHB_00850 1.87e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MNLEDHHB_00851 1.01e-87 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MNLEDHHB_00852 3.32e-93 yhaH - - S - - - Protein of unknown function (DUF805)
MNLEDHHB_00853 1.22e-139 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
MNLEDHHB_00854 3.42e-65 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MNLEDHHB_00855 6.31e-173 - - - S ko:K07090 - ko00000 membrane transporter protein
MNLEDHHB_00856 8.07e-163 - - - G - - - Belongs to the phosphoglycerate mutase family
MNLEDHHB_00857 1.3e-209 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
MNLEDHHB_00858 4.73e-31 - - - - - - - -
MNLEDHHB_00859 1.98e-163 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MNLEDHHB_00860 1.91e-233 - - - S - - - AAA domain
MNLEDHHB_00861 0.0 - - - I - - - Protein of unknown function (DUF2974)
MNLEDHHB_00862 2.48e-135 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
MNLEDHHB_00863 6.16e-260 pbpX1 - - V - - - Beta-lactamase
MNLEDHHB_00864 1.43e-251 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MNLEDHHB_00865 3.01e-272 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MNLEDHHB_00866 3.67e-180 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MNLEDHHB_00867 3.65e-222 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MNLEDHHB_00868 1.15e-280 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MNLEDHHB_00869 2.94e-108 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MNLEDHHB_00870 9.49e-317 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MNLEDHHB_00871 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MNLEDHHB_00872 1.16e-241 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MNLEDHHB_00873 0.0 potE - - E - - - Amino Acid
MNLEDHHB_00874 1.31e-135 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MNLEDHHB_00875 5.7e-299 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MNLEDHHB_00876 4.59e-278 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MNLEDHHB_00877 6.72e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MNLEDHHB_00878 3.27e-192 - - - - - - - -
MNLEDHHB_00879 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MNLEDHHB_00880 1.48e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MNLEDHHB_00881 1.29e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MNLEDHHB_00882 4.72e-219 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MNLEDHHB_00883 1.82e-198 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
MNLEDHHB_00884 1.38e-182 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MNLEDHHB_00885 3.28e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MNLEDHHB_00886 1.43e-151 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
MNLEDHHB_00887 5.28e-33 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
MNLEDHHB_00888 2.66e-29 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
MNLEDHHB_00889 4.39e-151 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
MNLEDHHB_00890 6.16e-110 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MNLEDHHB_00891 2.28e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MNLEDHHB_00892 2.3e-36 - 2.1.1.172 - J ko:K00564,ko:K10716 - ko00000,ko01000,ko02000,ko03009 Ion channel
MNLEDHHB_00893 7.09e-104 - 2.1.1.172 - J ko:K00564,ko:K10716 - ko00000,ko01000,ko02000,ko03009 Ion channel
MNLEDHHB_00894 3.57e-144 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MNLEDHHB_00895 1.53e-118 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MNLEDHHB_00896 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MNLEDHHB_00897 3.64e-58 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MNLEDHHB_00898 5.33e-141 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MNLEDHHB_00899 1.13e-44 - - - S - - - Protein of unknown function (DUF2508)
MNLEDHHB_00900 8.08e-147 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MNLEDHHB_00901 6.21e-68 yaaQ - - S - - - Cyclic-di-AMP receptor
MNLEDHHB_00902 7.72e-195 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MNLEDHHB_00903 2.32e-79 yabA - - L - - - Involved in initiation control of chromosome replication
MNLEDHHB_00904 7.51e-198 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MNLEDHHB_00905 6.78e-164 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
MNLEDHHB_00906 1.51e-111 - - - S - - - ECF transporter, substrate-specific component
MNLEDHHB_00907 1.33e-170 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
MNLEDHHB_00908 6.27e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
MNLEDHHB_00909 6.02e-247 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MNLEDHHB_00910 2.57e-160 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MNLEDHHB_00911 1.63e-231 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MNLEDHHB_00912 5.83e-161 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
MNLEDHHB_00913 1.93e-309 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
MNLEDHHB_00914 1.53e-156 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MNLEDHHB_00915 3.33e-30 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MNLEDHHB_00916 5.13e-05 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MNLEDHHB_00917 2.04e-83 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MNLEDHHB_00918 1.11e-50 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MNLEDHHB_00919 1.32e-135 - - - - - - - -
MNLEDHHB_00920 6.96e-206 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MNLEDHHB_00921 1.3e-144 - - - S - - - Peptidase family M23
MNLEDHHB_00922 3.16e-195 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MNLEDHHB_00923 4.83e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MNLEDHHB_00924 1.21e-89 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
MNLEDHHB_00925 5.82e-223 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
MNLEDHHB_00926 1.99e-126 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MNLEDHHB_00927 4.24e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MNLEDHHB_00928 2.68e-173 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MNLEDHHB_00929 5.4e-227 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MNLEDHHB_00930 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MNLEDHHB_00931 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MNLEDHHB_00932 7.08e-252 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MNLEDHHB_00933 1.4e-159 - - - S - - - Peptidase family M23
MNLEDHHB_00934 6.48e-89 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MNLEDHHB_00935 2.49e-158 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MNLEDHHB_00936 2.83e-196 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MNLEDHHB_00937 4.94e-308 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MNLEDHHB_00938 7.06e-81 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
MNLEDHHB_00939 3.13e-160 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MNLEDHHB_00940 8.47e-181 - - - - - - - -
MNLEDHHB_00941 1.36e-179 - - - - - - - -
MNLEDHHB_00942 8.02e-157 - - - - - - - -
MNLEDHHB_00943 0.0 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MNLEDHHB_00944 7.83e-38 - - - - - - - -
MNLEDHHB_00945 3.12e-135 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MNLEDHHB_00946 9.13e-182 - - - - - - - -
MNLEDHHB_00947 3.38e-226 - - - - - - - -
MNLEDHHB_00948 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
MNLEDHHB_00949 2.7e-233 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MNLEDHHB_00950 1.1e-259 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
MNLEDHHB_00951 1.18e-227 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
MNLEDHHB_00952 5.73e-210 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
MNLEDHHB_00953 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MNLEDHHB_00954 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MNLEDHHB_00955 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MNLEDHHB_00956 8.24e-115 ypmB - - S - - - Protein conserved in bacteria
MNLEDHHB_00957 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
MNLEDHHB_00958 1.98e-148 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
MNLEDHHB_00959 5.96e-146 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MNLEDHHB_00960 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
MNLEDHHB_00961 3.06e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MNLEDHHB_00962 1.54e-135 ypsA - - S - - - Belongs to the UPF0398 family
MNLEDHHB_00963 1.51e-90 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MNLEDHHB_00964 1.14e-275 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MNLEDHHB_00965 1.07e-294 cpdA - - S - - - Calcineurin-like phosphoesterase
MNLEDHHB_00966 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
MNLEDHHB_00967 4.5e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MNLEDHHB_00968 2.94e-208 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MNLEDHHB_00969 4.82e-254 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MNLEDHHB_00970 0.0 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MNLEDHHB_00971 0.0 FbpA - - K - - - Fibronectin-binding protein
MNLEDHHB_00972 2.32e-85 - - - - - - - -
MNLEDHHB_00973 1.07e-205 - - - S - - - EDD domain protein, DegV family
MNLEDHHB_00974 4.84e-172 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MNLEDHHB_00975 2.13e-256 - - - M - - - Glycosyl transferases group 1
MNLEDHHB_00976 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MNLEDHHB_00977 1.34e-195 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MNLEDHHB_00978 4.9e-71 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MNLEDHHB_00979 4.03e-256 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MNLEDHHB_00980 9e-106 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MNLEDHHB_00981 3.55e-53 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MNLEDHHB_00982 8.98e-288 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MNLEDHHB_00983 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MNLEDHHB_00984 4.89e-176 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
MNLEDHHB_00985 1.34e-113 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MNLEDHHB_00987 3.23e-140 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
MNLEDHHB_00988 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MNLEDHHB_00989 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MNLEDHHB_00990 2.33e-263 camS - - S - - - sex pheromone
MNLEDHHB_00991 2.94e-66 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MNLEDHHB_00992 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MNLEDHHB_00993 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MNLEDHHB_00994 2.65e-217 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
MNLEDHHB_00995 8.78e-144 ybbB - - S - - - Protein of unknown function (DUF1211)
MNLEDHHB_00996 6.09e-106 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
MNLEDHHB_00997 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MNLEDHHB_00998 1.03e-100 - - - C - - - Flavodoxin
MNLEDHHB_00999 4.68e-145 - - - I - - - Acid phosphatase homologues
MNLEDHHB_01000 2.08e-145 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
MNLEDHHB_01001 4.36e-264 - - - V - - - Beta-lactamase
MNLEDHHB_01002 3.17e-193 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
MNLEDHHB_01003 4.96e-121 - - - S - - - ECF-type riboflavin transporter, S component
MNLEDHHB_01004 1.18e-293 - - - S - - - Putative peptidoglycan binding domain
MNLEDHHB_01005 2.19e-149 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
MNLEDHHB_01006 1.12e-25 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 drug transmembrane transporter activity
MNLEDHHB_01007 0.0 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MNLEDHHB_01008 9.66e-46 - - - - - - - -
MNLEDHHB_01009 5.03e-20 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
MNLEDHHB_01010 7.71e-29 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
MNLEDHHB_01011 1.91e-78 - - - - - - - -
MNLEDHHB_01012 0.0 - - - P ko:K06148 - ko00000,ko02000 ABC transporter
MNLEDHHB_01013 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MNLEDHHB_01014 3.21e-117 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
MNLEDHHB_01015 3.06e-77 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
MNLEDHHB_01016 6.92e-55 - - - - - - - -
MNLEDHHB_01017 8.08e-88 - - - - - - - -
MNLEDHHB_01018 5.8e-137 - - - S - - - Fic/DOC family
MNLEDHHB_01019 4.75e-132 - - - - - - - -
MNLEDHHB_01020 4.04e-265 - - - EGP - - - Major Facilitator Superfamily
MNLEDHHB_01021 5.26e-173 - - - - - - - -
MNLEDHHB_01022 5.28e-244 - - - S - - - SLAP domain
MNLEDHHB_01023 1.21e-179 - - - S - - - Bacteriocin helveticin-J
MNLEDHHB_01024 3.8e-21 - - - S - - - Bacteriocin helveticin-J
MNLEDHHB_01025 5.44e-58 - - - - - - - -
MNLEDHHB_01026 4.81e-116 - - - - - - - -
MNLEDHHB_01027 7.54e-99 - - - K - - - Acetyltransferase (GNAT) domain
MNLEDHHB_01028 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
MNLEDHHB_01029 1.52e-119 - - - K - - - Bacterial regulatory proteins, tetR family
MNLEDHHB_01030 7.16e-314 qacA - - EGP - - - Major Facilitator
MNLEDHHB_01035 6.02e-124 - - - K - - - Acetyltransferase (GNAT) domain
MNLEDHHB_01037 6.5e-38 cspA - - K ko:K03704 - ko00000,ko03000 Cold shock protein
MNLEDHHB_01038 3.03e-290 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
MNLEDHHB_01039 1.09e-80 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
MNLEDHHB_01040 1.43e-117 ydhK - - M - - - Protein of unknown function (DUF1541)
MNLEDHHB_01041 1.01e-51 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
MNLEDHHB_01042 1.15e-47 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
MNLEDHHB_01043 5.42e-19 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
MNLEDHHB_01045 5.16e-211 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MNLEDHHB_01046 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MNLEDHHB_01047 3.51e-308 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MNLEDHHB_01048 1.26e-68 - - - - - - - -
MNLEDHHB_01049 8.53e-153 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
MNLEDHHB_01050 9.65e-105 - - - S - - - Threonine/Serine exporter, ThrE
MNLEDHHB_01051 6.57e-177 - - - S - - - Putative threonine/serine exporter
MNLEDHHB_01052 0.0 - - - S - - - ABC transporter
MNLEDHHB_01053 2.34e-74 - - - - - - - -
MNLEDHHB_01054 3.26e-128 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MNLEDHHB_01055 3.37e-152 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MNLEDHHB_01056 4.9e-283 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MNLEDHHB_01057 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MNLEDHHB_01058 1.9e-34 - - - S - - - Fic/DOC family
MNLEDHHB_01059 6.85e-65 - - - S - - - Fic/DOC family
MNLEDHHB_01060 4.43e-56 - - - S - - - Enterocin A Immunity
MNLEDHHB_01061 1.22e-53 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MNLEDHHB_01062 3.17e-25 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MNLEDHHB_01063 1.62e-59 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MNLEDHHB_01064 7.01e-89 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MNLEDHHB_01065 1.34e-297 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MNLEDHHB_01066 2.16e-170 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MNLEDHHB_01067 1.63e-152 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MNLEDHHB_01068 6.02e-201 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MNLEDHHB_01069 1.25e-17 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
MNLEDHHB_01070 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
MNLEDHHB_01071 2.54e-214 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MNLEDHHB_01072 1.15e-178 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
MNLEDHHB_01075 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MNLEDHHB_01076 6.09e-240 flp - - V - - - Beta-lactamase
MNLEDHHB_01077 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
MNLEDHHB_01078 1.59e-74 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
MNLEDHHB_01079 2.8e-114 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
MNLEDHHB_01080 2.75e-09 - - - - - - - -
MNLEDHHB_01081 1.31e-122 tdh 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
MNLEDHHB_01082 1.53e-162 - - - S - - - KR domain
MNLEDHHB_01083 1.25e-137 - - - C - - - nitroreductase
MNLEDHHB_01084 1.86e-82 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
MNLEDHHB_01085 1.89e-91 - - - GK - - - ROK family
MNLEDHHB_01087 9.24e-79 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MNLEDHHB_01088 7.31e-75 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
MNLEDHHB_01089 7.23e-22 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
MNLEDHHB_01090 6.12e-118 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MNLEDHHB_01091 2.62e-308 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MNLEDHHB_01092 3.23e-45 - - - - - - - -
MNLEDHHB_01093 8.26e-82 - - - S - - - SLAP domain
MNLEDHHB_01094 3.1e-236 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MNLEDHHB_01095 8.9e-51 - - - - - - - -
MNLEDHHB_01096 1.1e-132 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
MNLEDHHB_01099 1.37e-25 - - - - - - - -
MNLEDHHB_01102 3.36e-82 - - - L - - - Reverse transcriptase (RNA-dependent DNA polymerase)
MNLEDHHB_01103 4.24e-90 - - - L - - - Reverse transcriptase (RNA-dependent DNA polymerase)
MNLEDHHB_01106 3.9e-122 - - - L - - - reverse transcriptase
MNLEDHHB_01107 1.76e-233 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MNLEDHHB_01108 1.93e-149 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MNLEDHHB_01109 1.26e-209 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MNLEDHHB_01110 3.87e-266 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MNLEDHHB_01111 1.91e-280 - - - KQ - - - helix_turn_helix, mercury resistance
MNLEDHHB_01114 1.94e-268 - - - K - - - IrrE N-terminal-like domain
MNLEDHHB_01115 6.02e-162 - - - - - - - -
MNLEDHHB_01116 4.23e-49 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
MNLEDHHB_01118 2.33e-238 - - - S - - - Cysteine-rich secretory protein family
MNLEDHHB_01119 1.36e-284 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MNLEDHHB_01121 5.9e-239 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MNLEDHHB_01122 2.43e-187 epsB - - M - - - biosynthesis protein
MNLEDHHB_01123 1.17e-157 ywqD - - D - - - Capsular exopolysaccharide family
MNLEDHHB_01124 8.08e-187 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
MNLEDHHB_01125 8.83e-154 epsE2 - - M - - - Bacterial sugar transferase
MNLEDHHB_01126 5.79e-214 - - - M - - - Glycosyltransferase
MNLEDHHB_01127 1.65e-106 - - - M - - - Oligosaccharide biosynthesis protein Alg14 like
MNLEDHHB_01128 4.19e-101 - - - S - - - Glycosyltransferase family 28 C-terminal domain
MNLEDHHB_01129 5.42e-177 - - - M - - - Glycosyltransferase like family 2
MNLEDHHB_01130 9.34e-132 - - - S - - - Bacterial transferase hexapeptide (six repeats)
MNLEDHHB_01131 6.98e-196 cps3F - - - - - - -
MNLEDHHB_01132 1.02e-145 - - - M - - - Glycosyltransferase like family 2
MNLEDHHB_01133 6.6e-292 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MNLEDHHB_01134 8.74e-194 licD - - M ko:K07271 - ko00000,ko01000 LicD family
MNLEDHHB_01135 1.25e-262 - - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MNLEDHHB_01136 1.45e-29 tagD 2.7.7.15, 2.7.7.39 - IM ko:K00968,ko:K00980 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 ko00000,ko00001,ko00002,ko01000 Glycerol-3-phosphate cytidylyltransferase
MNLEDHHB_01137 3.36e-33 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
MNLEDHHB_01138 8.41e-11 - - - M - - - Domain of unknown function (DUF4422)
MNLEDHHB_01141 8.23e-249 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
MNLEDHHB_01142 2.3e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MNLEDHHB_01143 8.46e-265 potE - - E - - - Amino Acid
MNLEDHHB_01144 9.48e-232 - - - - - - - -
MNLEDHHB_01145 9.19e-135 - - - - - - - -
MNLEDHHB_01146 9.68e-159 - - - S - - - L-ascorbic acid biosynthetic process
MNLEDHHB_01147 3.6e-92 - - - O - - - OsmC-like protein
MNLEDHHB_01148 2.62e-264 - - - EGP - - - Major Facilitator Superfamily
MNLEDHHB_01149 1.11e-70 sptS - - T - - - Histidine kinase
MNLEDHHB_01150 5.66e-122 sptS - - T - - - Histidine kinase
MNLEDHHB_01151 3.23e-65 - - - T - - - Region found in RelA / SpoT proteins
MNLEDHHB_01152 7.78e-38 - - - T - - - Region found in RelA / SpoT proteins
MNLEDHHB_01153 1.01e-311 - - - S - - - SLAP domain
MNLEDHHB_01154 1.08e-249 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MNLEDHHB_01155 1.76e-185 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MNLEDHHB_01156 3.3e-282 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MNLEDHHB_01158 1.92e-123 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MNLEDHHB_01159 1.3e-239 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MNLEDHHB_01160 7.77e-314 yifK - - E ko:K03293 - ko00000 Amino acid permease
MNLEDHHB_01162 5.43e-48 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MNLEDHHB_01163 2.94e-117 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MNLEDHHB_01164 1.26e-126 - - - I - - - PAP2 superfamily
MNLEDHHB_01165 1.53e-165 - - - S - - - Uncharacterised protein, DegV family COG1307
MNLEDHHB_01166 1.23e-311 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MNLEDHHB_01167 2.3e-99 - - - S - - - Domain of unknown function (DUF4767)
MNLEDHHB_01168 3.93e-109 yfhC - - C - - - nitroreductase
MNLEDHHB_01169 3.61e-157 - - - K ko:K03492 - ko00000,ko03000 UTRA
MNLEDHHB_01170 1.57e-276 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MNLEDHHB_01171 4.15e-88 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MNLEDHHB_01172 7.67e-90 - - - S - - - Domain of unknown function (DUF3284)
MNLEDHHB_01173 6.67e-40 - - - K - - - Protein of unknown function (DUF4065)
MNLEDHHB_01174 6.29e-307 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MNLEDHHB_01175 1.46e-71 - - - - - - - -
MNLEDHHB_01176 2.23e-117 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MNLEDHHB_01177 1.18e-274 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
MNLEDHHB_01178 8.73e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
MNLEDHHB_01179 3.54e-190 yycI - - S - - - YycH protein
MNLEDHHB_01180 8.07e-314 yycH - - S - - - YycH protein
MNLEDHHB_01181 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MNLEDHHB_01182 2.8e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MNLEDHHB_01184 3.67e-45 - - - - - - - -
MNLEDHHB_01186 6.83e-68 - - - K - - - Helix-turn-helix XRE-family like proteins
MNLEDHHB_01187 3.57e-61 - - - E - - - Zn peptidase
MNLEDHHB_01188 4.56e-166 - - - I - - - Acyl-transferase
MNLEDHHB_01189 8.55e-184 arbx - - M - - - Glycosyl transferase family 8
MNLEDHHB_01190 2.94e-236 - - - M - - - Glycosyl transferase family 8
MNLEDHHB_01191 1.29e-208 - - - M - - - Glycosyl transferase family 8
MNLEDHHB_01192 3.77e-213 arbZ - - I - - - Phosphate acyltransferases
MNLEDHHB_01193 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
MNLEDHHB_01194 1.17e-73 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MNLEDHHB_01195 4.67e-290 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MNLEDHHB_01196 2.36e-60 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MNLEDHHB_01197 1.64e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MNLEDHHB_01198 1.39e-174 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MNLEDHHB_01199 1.32e-73 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MNLEDHHB_01200 3.16e-152 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
MNLEDHHB_01201 5.3e-189 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MNLEDHHB_01202 1.99e-145 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MNLEDHHB_01203 1.85e-49 ynzC - - S - - - UPF0291 protein
MNLEDHHB_01204 6.43e-41 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
MNLEDHHB_01205 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MNLEDHHB_01206 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MNLEDHHB_01207 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MNLEDHHB_01208 9.59e-289 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MNLEDHHB_01209 1.46e-145 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
MNLEDHHB_01210 4.99e-252 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
MNLEDHHB_01211 1.1e-180 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MNLEDHHB_01212 2.15e-236 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MNLEDHHB_01213 2.38e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MNLEDHHB_01214 8.57e-122 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MNLEDHHB_01215 2.23e-178 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MNLEDHHB_01216 1.62e-189 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MNLEDHHB_01217 9.05e-254 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MNLEDHHB_01218 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MNLEDHHB_01219 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MNLEDHHB_01220 8.01e-107 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MNLEDHHB_01221 6.69e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MNLEDHHB_01222 9.2e-64 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
MNLEDHHB_01223 5.4e-63 ylxQ - - J - - - ribosomal protein
MNLEDHHB_01224 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MNLEDHHB_01225 4.6e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MNLEDHHB_01226 6.73e-211 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MNLEDHHB_01227 6.52e-226 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MNLEDHHB_01228 1.19e-237 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MNLEDHHB_01229 1.14e-114 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MNLEDHHB_01230 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MNLEDHHB_01231 3.62e-268 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MNLEDHHB_01232 1.13e-30 - - - - - - - -
MNLEDHHB_01233 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MNLEDHHB_01234 1.31e-149 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
MNLEDHHB_01235 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MNLEDHHB_01236 8.09e-122 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MNLEDHHB_01237 1.26e-154 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MNLEDHHB_01238 6.95e-37 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MNLEDHHB_01239 3.84e-189 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
MNLEDHHB_01240 2.15e-75 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MNLEDHHB_01241 2.22e-116 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MNLEDHHB_01242 3.42e-73 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MNLEDHHB_01243 1.78e-107 - 3.4.21.96 - S ko:K01361 - ko00000,ko01000,ko01002,ko03110 SLAP domain
MNLEDHHB_01244 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
MNLEDHHB_01245 9.46e-200 lysR5 - - K - - - LysR substrate binding domain
MNLEDHHB_01246 8.99e-261 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
MNLEDHHB_01247 7.26e-242 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MNLEDHHB_01248 5.65e-211 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
MNLEDHHB_01249 7.45e-124 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MNLEDHHB_01250 3.04e-154 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MNLEDHHB_01251 1.79e-248 - - - S - - - DUF218 domain
MNLEDHHB_01252 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MNLEDHHB_01253 1.33e-126 - - - S - - - ECF transporter, substrate-specific component
MNLEDHHB_01254 2.08e-203 - - - S - - - Aldo/keto reductase family
MNLEDHHB_01255 1.34e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MNLEDHHB_01256 3.68e-33 - - - K - - - rpiR family
MNLEDHHB_01257 9.71e-67 - - - K - - - rpiR family
MNLEDHHB_01258 3.29e-180 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
MNLEDHHB_01259 5.12e-233 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Beta-lactamase
MNLEDHHB_01260 2.49e-162 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MNLEDHHB_01261 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MNLEDHHB_01263 2.61e-12 - - - - - - - -
MNLEDHHB_01264 4.67e-15 - - - S - - - SLAP domain
MNLEDHHB_01265 0.0 - - - S - - - SLAP domain
MNLEDHHB_01267 4.93e-41 - - - - - - - -
MNLEDHHB_01269 4.61e-36 - - - - - - - -
MNLEDHHB_01270 2.09e-148 - - - G - - - Peptidase_C39 like family
MNLEDHHB_01271 5.96e-11 - - - G - - - Peptidase_C39 like family
MNLEDHHB_01272 2.24e-151 - - - M - - - NlpC/P60 family
MNLEDHHB_01273 1.43e-49 - - - M - - - NlpC/P60 family
MNLEDHHB_01274 4.25e-24 - - - M - - - NlpC/P60 family
MNLEDHHB_01275 5.68e-116 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
MNLEDHHB_01276 0.0 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
MNLEDHHB_01277 5.12e-71 yitW - - S - - - Iron-sulfur cluster assembly protein
MNLEDHHB_01278 2.99e-194 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MNLEDHHB_01279 3.17e-157 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
MNLEDHHB_01280 7.73e-63 - - - - - - - -
MNLEDHHB_01281 1.31e-63 - - - - - - - -
MNLEDHHB_01282 2.45e-151 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MNLEDHHB_01283 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MNLEDHHB_01284 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MNLEDHHB_01285 3.72e-20 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
MNLEDHHB_01286 2.77e-195 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
MNLEDHHB_01287 2.96e-30 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
MNLEDHHB_01288 2.74e-81 - - - M - - - LPXTG-motif cell wall anchor domain protein
MNLEDHHB_01289 6.68e-29 - - - - - - - -
MNLEDHHB_01290 3.43e-76 - - - CO ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin
MNLEDHHB_01291 8.05e-149 - - - K - - - Rhodanese Homology Domain
MNLEDHHB_01292 4.43e-221 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MNLEDHHB_01293 4.81e-21 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
MNLEDHHB_01294 2.26e-17 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
MNLEDHHB_01295 1.94e-55 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
MNLEDHHB_01296 1.54e-37 - - - S - - - PD-(D/E)XK nuclease family transposase
MNLEDHHB_01297 4.56e-93 - - - S - - - Uncharacterised protein family (UPF0236)
MNLEDHHB_01298 4.39e-177 yxeH - - S - - - hydrolase
MNLEDHHB_01299 4.59e-49 - - - S - - - Enterocin A Immunity
MNLEDHHB_01300 1.16e-204 msmR - - K - - - AraC-like ligand binding domain
MNLEDHHB_01301 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MNLEDHHB_01302 1.57e-97 - - - S - - - Haloacid dehalogenase-like hydrolase
MNLEDHHB_01303 5.19e-310 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MNLEDHHB_01304 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MNLEDHHB_01305 4.53e-98 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MNLEDHHB_01306 3.22e-85 - - - S - - - Domain of unknown function (DUF1934)
MNLEDHHB_01307 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MNLEDHHB_01308 5.78e-57 - - - - - - - -
MNLEDHHB_01309 4.1e-188 - - - GK - - - ROK family
MNLEDHHB_01310 2.11e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MNLEDHHB_01311 7.43e-245 - - - S - - - SLAP domain
MNLEDHHB_01312 4.47e-161 - - - - - - - -
MNLEDHHB_01313 1.24e-139 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MNLEDHHB_01314 2.23e-35 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MNLEDHHB_01315 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MNLEDHHB_01316 9e-46 ykzG - - S - - - Belongs to the UPF0356 family
MNLEDHHB_01317 1.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MNLEDHHB_01318 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MNLEDHHB_01319 3.86e-263 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MNLEDHHB_01320 1.72e-71 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
MNLEDHHB_01321 5e-124 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
MNLEDHHB_01322 6.77e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MNLEDHHB_01323 3.21e-244 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MNLEDHHB_01324 2.7e-127 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
MNLEDHHB_01325 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MNLEDHHB_01326 1.17e-222 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MNLEDHHB_01327 4.42e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MNLEDHHB_01328 1.92e-44 - - - S - - - Pyridoxamine 5'-phosphate oxidase
MNLEDHHB_01329 5.36e-219 yobV3 - - K - - - WYL domain
MNLEDHHB_01330 1.14e-87 - - - S - - - pyridoxamine 5-phosphate
MNLEDHHB_01331 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
MNLEDHHB_01332 1.23e-180 - - - K - - - Transcriptional regulator
MNLEDHHB_01333 4.14e-98 - - - S - - - NADPH-dependent FMN reductase
MNLEDHHB_01334 3.01e-139 adh1 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MNLEDHHB_01335 1.99e-54 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
MNLEDHHB_01336 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
MNLEDHHB_01337 2.95e-43 - - - C - - - Heavy-metal-associated domain
MNLEDHHB_01338 4.77e-118 dpsB - - P - - - Belongs to the Dps family
MNLEDHHB_01339 1.39e-141 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
MNLEDHHB_01340 2.67e-71 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MNLEDHHB_01341 1.56e-39 - - - - - - - -
MNLEDHHB_01342 0.0 - - - S - - - Protein of unknown function DUF262
MNLEDHHB_01343 1.6e-22 - - - L - - - helicase
MNLEDHHB_01344 3.02e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MNLEDHHB_01345 3.82e-90 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MNLEDHHB_01346 1.43e-129 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MNLEDHHB_01347 8.53e-34 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MNLEDHHB_01348 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MNLEDHHB_01349 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MNLEDHHB_01350 2.41e-45 - - - - - - - -
MNLEDHHB_01351 4.1e-118 comX - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
MNLEDHHB_01352 1.24e-178 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MNLEDHHB_01353 2.1e-99 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MNLEDHHB_01354 9.02e-252 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MNLEDHHB_01355 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MNLEDHHB_01356 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MNLEDHHB_01357 1.56e-132 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
MNLEDHHB_01358 2.91e-67 - - - - - - - -
MNLEDHHB_01359 2.48e-18 - - - - - - - -
MNLEDHHB_01360 5.45e-121 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MNLEDHHB_01361 2.85e-58 - - - S - - - C4-dicarboxylate anaerobic carrier
MNLEDHHB_01362 1.74e-36 - - - S - - - C4-dicarboxylate anaerobic carrier
MNLEDHHB_01363 9.58e-64 - - - S - - - C4-dicarboxylate anaerobic carrier
MNLEDHHB_01364 1.96e-42 - - - S - - - C4-dicarboxylate anaerobic carrier
MNLEDHHB_01365 4.77e-258 - - - - - - - -
MNLEDHHB_01366 4.23e-265 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
MNLEDHHB_01367 3.9e-306 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MNLEDHHB_01368 5.94e-42 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MNLEDHHB_01369 3.24e-101 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MNLEDHHB_01370 2.77e-78 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
MNLEDHHB_01371 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MNLEDHHB_01372 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MNLEDHHB_01373 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
MNLEDHHB_01374 0.0 - - - L - - - Probable transposase
MNLEDHHB_01375 1.25e-136 - - - L - - - Resolvase, N terminal domain
MNLEDHHB_01376 9.74e-98 - - - S - - - Protein of unknown function (DUF3021)
MNLEDHHB_01377 6.55e-97 - - - K - - - LytTr DNA-binding domain
MNLEDHHB_01378 6.34e-136 - 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
MNLEDHHB_01380 5.17e-08 - - - S - - - Protein of unknown function (DUF3923)
MNLEDHHB_01381 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
MNLEDHHB_01382 5.75e-124 - - - K - - - Acetyltransferase (GNAT) domain
MNLEDHHB_01383 1.86e-49 - - - K - - - helix_turn_helix, mercury resistance
MNLEDHHB_01384 1.22e-44 - - - K - - - helix_turn_helix, mercury resistance
MNLEDHHB_01387 7.52e-80 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
MNLEDHHB_01388 2.73e-60 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
MNLEDHHB_01389 1.84e-135 - - - K - - - Helix-turn-helix domain
MNLEDHHB_01390 3.44e-124 - - - S - - - Bacteriocin helveticin-J
MNLEDHHB_01391 4.65e-100 - - - S - - - SLAP domain
MNLEDHHB_01392 6.55e-221 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MNLEDHHB_01393 3.5e-123 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MNLEDHHB_01394 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MNLEDHHB_01395 1.17e-219 - - - K - - - helix_turn_helix, arabinose operon control protein
MNLEDHHB_01396 3.7e-204 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MNLEDHHB_01397 2.37e-124 lemA - - S ko:K03744 - ko00000 LemA family
MNLEDHHB_01398 1.07e-245 ysdE - - P - - - Citrate transporter
MNLEDHHB_01399 1.36e-91 - - - S - - - Iron-sulphur cluster biosynthesis
MNLEDHHB_01400 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
MNLEDHHB_01401 0.0 - - - S - - - SH3-like domain
MNLEDHHB_01402 4.53e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MNLEDHHB_01403 8.23e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MNLEDHHB_01404 1.27e-247 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MNLEDHHB_01405 2.09e-211 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MNLEDHHB_01406 1.26e-107 - - - S - - - Short repeat of unknown function (DUF308)
MNLEDHHB_01407 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MNLEDHHB_01408 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MNLEDHHB_01409 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MNLEDHHB_01410 1.1e-62 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MNLEDHHB_01411 2.29e-114 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MNLEDHHB_01412 9.83e-42 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MNLEDHHB_01413 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MNLEDHHB_01414 2.66e-09 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MNLEDHHB_01415 2e-240 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MNLEDHHB_01416 7.49e-199 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MNLEDHHB_01417 2.39e-228 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MNLEDHHB_01418 5.54e-51 - - - - - - - -
MNLEDHHB_01419 3.57e-237 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MNLEDHHB_01420 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MNLEDHHB_01421 6.59e-124 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MNLEDHHB_01422 1.99e-170 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
MNLEDHHB_01423 2.89e-310 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
MNLEDHHB_01424 1.14e-150 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
MNLEDHHB_01425 3.59e-264 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
MNLEDHHB_01426 5.81e-284 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MNLEDHHB_01427 8.51e-246 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MNLEDHHB_01428 3e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MNLEDHHB_01429 1.33e-186 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
MNLEDHHB_01430 1.55e-168 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MNLEDHHB_01431 1.85e-301 ymfH - - S - - - Peptidase M16
MNLEDHHB_01432 4.05e-289 ymfF - - S - - - Peptidase M16 inactive domain protein
MNLEDHHB_01433 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MNLEDHHB_01434 4.46e-90 WQ51_03320 - - S - - - Protein of unknown function (DUF1149)
MNLEDHHB_01435 8.64e-136 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MNLEDHHB_01436 8.55e-270 XK27_05220 - - S - - - AI-2E family transporter
MNLEDHHB_01437 3.3e-86 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MNLEDHHB_01438 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
MNLEDHHB_01439 4.12e-255 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
MNLEDHHB_01440 2.05e-88 - - - S - - - SNARE associated Golgi protein
MNLEDHHB_01441 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
MNLEDHHB_01442 6.77e-216 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MNLEDHHB_01443 2.52e-197 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MNLEDHHB_01444 1.63e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MNLEDHHB_01445 6.91e-139 - - - S - - - CYTH
MNLEDHHB_01446 5.3e-144 yjbH - - Q - - - Thioredoxin
MNLEDHHB_01447 1.08e-203 coiA - - S ko:K06198 - ko00000 Competence protein
MNLEDHHB_01448 2.5e-176 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MNLEDHHB_01449 1.08e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MNLEDHHB_01450 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MNLEDHHB_01451 1.29e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
MNLEDHHB_01452 3.55e-39 - - - - - - - -
MNLEDHHB_01453 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
MNLEDHHB_01454 4.17e-60 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
MNLEDHHB_01455 3.53e-275 - - - S - - - SLAP domain
MNLEDHHB_01457 1.5e-169 mrr2 - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
MNLEDHHB_01460 9.07e-73 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
MNLEDHHB_01461 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
MNLEDHHB_01462 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 DEAD/DEAH box helicase
MNLEDHHB_01463 1.31e-295 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MNLEDHHB_01464 8.36e-154 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MNLEDHHB_01465 1e-119 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MNLEDHHB_01466 9.21e-161 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
MNLEDHHB_01467 4.32e-21 - - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 PFAM Lanthionine synthetase
MNLEDHHB_01468 8e-81 - - - S - - - Lantibiotic dehydratase, C terminus
MNLEDHHB_01470 6.02e-114 - - - L - - - Transposase DDE domain
MNLEDHHB_01471 7.07e-113 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
MNLEDHHB_01472 7.45e-120 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
MNLEDHHB_01473 6.1e-64 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MNLEDHHB_01475 1.86e-303 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MNLEDHHB_01476 1.75e-194 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MNLEDHHB_01477 9.06e-159 - - - M - - - ErfK YbiS YcfS YnhG
MNLEDHHB_01478 8.77e-65 padR - - K - - - Virulence activator alpha C-term
MNLEDHHB_01479 1.9e-42 padR - - K - - - Virulence activator alpha C-term
MNLEDHHB_01480 5.8e-137 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
MNLEDHHB_01481 1.46e-140 - - - S - - - PD-(D/E)XK nuclease family transposase
MNLEDHHB_01482 1.88e-18 - - - S - - - PD-(D/E)XK nuclease family transposase
MNLEDHHB_01483 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MNLEDHHB_01484 9.99e-216 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
MNLEDHHB_01485 1.11e-113 - - - L - - - NUDIX domain
MNLEDHHB_01486 5.88e-47 - - - - - - - -
MNLEDHHB_01487 2.58e-14 - - - - - - - -
MNLEDHHB_01488 2.65e-165 - - - - - - - -
MNLEDHHB_01489 6.82e-101 - 1.1.1.29 - CH ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MNLEDHHB_01490 2.01e-104 - 1.1.1.29 - CH ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MNLEDHHB_01491 3.86e-61 - - - - - - - -
MNLEDHHB_01492 4.72e-72 - - - - - - - -
MNLEDHHB_01493 1.07e-80 ptsG 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MNLEDHHB_01494 1.1e-277 - - - EGP ko:K08196,ko:K08369 - ko00000,ko02000 Major Facilitator
MNLEDHHB_01495 9.34e-173 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MNLEDHHB_01496 7.28e-269 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MNLEDHHB_01497 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
MNLEDHHB_01498 2.11e-271 - - - Q - - - Imidazolonepropionase and related amidohydrolases
MNLEDHHB_01499 4.43e-71 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
MNLEDHHB_01512 1.14e-277 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
MNLEDHHB_01513 1.28e-256 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MNLEDHHB_01514 1.85e-221 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MNLEDHHB_01515 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MNLEDHHB_01516 1.3e-40 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MNLEDHHB_01517 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MNLEDHHB_01518 1.3e-100 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MNLEDHHB_01519 6.23e-244 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MNLEDHHB_01520 4.35e-238 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
MNLEDHHB_01521 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
MNLEDHHB_01522 1.25e-241 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MNLEDHHB_01523 1.81e-29 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MNLEDHHB_01524 2.5e-59 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MNLEDHHB_01525 3.11e-141 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MNLEDHHB_01526 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MNLEDHHB_01527 1.16e-114 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
MNLEDHHB_01528 2.26e-89 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
MNLEDHHB_01529 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MNLEDHHB_01530 0.0 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
MNLEDHHB_01531 1.04e-20 - - - V - - - Abi-like protein
MNLEDHHB_01532 7.82e-10 - - - V - - - Abi-like protein
MNLEDHHB_01533 2.36e-22 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
MNLEDHHB_01535 8.68e-41 - - - V - - - Abi-like protein
MNLEDHHB_01536 2.01e-21 - - - V - - - Abi-like protein
MNLEDHHB_01537 1.56e-201 - - - - - - - -
MNLEDHHB_01538 1.03e-207 - - - - - - - -
MNLEDHHB_01539 9.11e-139 - - - - - - - -
MNLEDHHB_01540 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MNLEDHHB_01541 7.4e-89 ynbB - - P - - - aluminum resistance
MNLEDHHB_01542 1.58e-109 ynbB - - P - - - aluminum resistance
MNLEDHHB_01543 4.76e-61 ynbB - - P - - - aluminum resistance
MNLEDHHB_01544 3.23e-218 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MNLEDHHB_01545 1.73e-89 yqhL - - P - - - Rhodanese-like protein
MNLEDHHB_01546 2.45e-44 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
MNLEDHHB_01547 1.73e-148 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
MNLEDHHB_01548 1.27e-128 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MNLEDHHB_01549 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MNLEDHHB_01550 1.57e-172 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MNLEDHHB_01551 1.64e-105 - - - L - - - Transposase and inactivated derivatives, IS30 family
MNLEDHHB_01552 2.63e-70 - - - L - - - Transposase and inactivated derivatives, IS30 family
MNLEDHHB_01553 5.55e-226 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
MNLEDHHB_01554 1.77e-55 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Quinolinate phosphoribosyl transferase, C-terminal domain
MNLEDHHB_01555 3.11e-129 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Quinolinate phosphoribosyl transferase, C-terminal domain
MNLEDHHB_01556 1.82e-198 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
MNLEDHHB_01557 5.55e-181 - - - L ko:K07485 - ko00000 Transposase
MNLEDHHB_01558 4.85e-73 - - - L - - - Resolvase, N terminal domain
MNLEDHHB_01559 3.62e-22 - - - S - - - Transglycosylase associated protein
MNLEDHHB_01560 0.0 - - - L - - - Transposase
MNLEDHHB_01561 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MNLEDHHB_01562 1.01e-168 treR - - K ko:K03486 - ko00000,ko03000 UTRA
MNLEDHHB_01563 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MNLEDHHB_01564 0.0 - - - - - - - -
MNLEDHHB_01565 1.43e-105 - - - - - - - -
MNLEDHHB_01566 2.03e-140 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MNLEDHHB_01567 1.37e-83 - - - S - - - ASCH domain
MNLEDHHB_01568 4.93e-70 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 lactoylglutathione lyase activity
MNLEDHHB_01569 1.5e-52 - - - - - - - -
MNLEDHHB_01570 4.47e-81 - - - K ko:K06977 - ko00000 acetyltransferase
MNLEDHHB_01571 1.91e-124 - - - - - - - -
MNLEDHHB_01572 3.49e-48 - - - - - - - -
MNLEDHHB_01573 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
MNLEDHHB_01574 6.25e-171 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
MNLEDHHB_01575 2.25e-239 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
MNLEDHHB_01576 3.47e-20 - - - - - - - -
MNLEDHHB_01577 6.15e-161 - - - - - - - -
MNLEDHHB_01578 9.94e-304 - - - S - - - response to antibiotic
MNLEDHHB_01579 3.24e-25 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MNLEDHHB_01580 4.36e-162 gpm2 - - G - - - Phosphoglycerate mutase family
MNLEDHHB_01581 6.11e-159 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
MNLEDHHB_01582 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MNLEDHHB_01583 8.97e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MNLEDHHB_01584 1.51e-139 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
MNLEDHHB_01585 3.56e-191 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MNLEDHHB_01586 1.42e-102 yjcF - - S - - - Acetyltransferase (GNAT) domain
MNLEDHHB_01587 2.29e-131 - - - E - - - GDSL-like Lipase/Acylhydrolase
MNLEDHHB_01588 7.88e-219 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MNLEDHHB_01589 2.28e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MNLEDHHB_01590 7.58e-304 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MNLEDHHB_01591 1.95e-118 - - - S - - - Peptidase propeptide and YPEB domain
MNLEDHHB_01592 9.4e-89 yybA - - K - - - Transcriptional regulator
MNLEDHHB_01593 3.57e-112 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MNLEDHHB_01594 4.91e-101 - - - S - - - Peptidase propeptide and YPEB domain
MNLEDHHB_01595 2.65e-123 - - - F - - - Nucleoside 2-deoxyribosyltransferase
MNLEDHHB_01596 1.1e-234 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MNLEDHHB_01597 2.91e-229 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MNLEDHHB_01598 0.0 - - - V - - - ABC transporter transmembrane region
MNLEDHHB_01599 5.09e-160 - - - S - - - PAS domain
MNLEDHHB_01600 3.9e-181 - - - - - - - -
MNLEDHHB_01601 1.91e-180 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
MNLEDHHB_01602 7.72e-84 - - - S - - - Protein of unknown function (DUF3290)
MNLEDHHB_01603 1.54e-135 yviA - - S - - - Protein of unknown function (DUF421)
MNLEDHHB_01604 2.96e-202 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MNLEDHHB_01605 1.79e-216 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
MNLEDHHB_01606 5.95e-203 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
MNLEDHHB_01607 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MNLEDHHB_01608 1.56e-255 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
MNLEDHHB_01609 1.15e-202 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
MNLEDHHB_01610 6.84e-188 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MNLEDHHB_01611 0.0 - - - S - - - Zn-dependent metallo-hydrolase RNA specificity domain
MNLEDHHB_01612 3.36e-307 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MNLEDHHB_01613 1.36e-214 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MNLEDHHB_01614 8.59e-203 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
MNLEDHHB_01615 3.9e-125 yobS - - K - - - Bacterial regulatory proteins, tetR family
MNLEDHHB_01616 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
MNLEDHHB_01617 1.2e-207 - - - - - - - -
MNLEDHHB_01618 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MNLEDHHB_01619 1.59e-141 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
MNLEDHHB_01620 8.73e-21 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
MNLEDHHB_01621 4.02e-196 - - - I - - - alpha/beta hydrolase fold
MNLEDHHB_01622 6.7e-141 - - - S - - - SNARE associated Golgi protein
MNLEDHHB_01623 3.96e-126 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MNLEDHHB_01624 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MNLEDHHB_01625 9.02e-56 - - - - - - - -
MNLEDHHB_01626 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MNLEDHHB_01627 1.33e-289 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MNLEDHHB_01628 5.65e-230 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
MNLEDHHB_01629 4.89e-159 - - - S - - - membrane
MNLEDHHB_01630 2.15e-101 - - - K - - - LytTr DNA-binding domain
MNLEDHHB_01631 8.71e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MNLEDHHB_01632 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
MNLEDHHB_01633 1.32e-288 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MNLEDHHB_01634 4.76e-221 - - - - - - - -
MNLEDHHB_01635 3.97e-77 lysM - - M - - - LysM domain
MNLEDHHB_01637 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
MNLEDHHB_01638 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
MNLEDHHB_01639 1.58e-33 - - - - - - - -
MNLEDHHB_01640 1.27e-237 - - - S - - - Putative peptidoglycan binding domain
MNLEDHHB_01641 5.4e-27 - - - C - - - Domain of unknown function (DUF4931)
MNLEDHHB_01642 1.86e-137 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MNLEDHHB_01643 2.41e-31 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MNLEDHHB_01645 1.53e-102 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
MNLEDHHB_01646 1.78e-218 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
MNLEDHHB_01647 9.44e-169 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MNLEDHHB_01648 1.5e-150 - - - G - - - Antibiotic biosynthesis monooxygenase
MNLEDHHB_01649 1.25e-128 - - - G - - - Histidine phosphatase superfamily (branch 1)
MNLEDHHB_01650 2.77e-144 - - - G - - - Phosphoglycerate mutase family
MNLEDHHB_01651 1.13e-248 - - - D - - - nuclear chromosome segregation
MNLEDHHB_01652 8.58e-126 - - - M - - - LysM domain protein
MNLEDHHB_01653 5.26e-19 - - - - - - - -
MNLEDHHB_01654 2.76e-19 - - - S - - - Enterocin A Immunity
MNLEDHHB_01655 1.73e-30 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MNLEDHHB_01656 7.56e-157 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MNLEDHHB_01657 3.01e-153 - - - S - - - PAS domain
MNLEDHHB_01658 9.27e-173 nirC - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
MNLEDHHB_01659 2.32e-202 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
MNLEDHHB_01660 2.71e-52 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
MNLEDHHB_01661 1.97e-140 pncA - - Q - - - Isochorismatase family
MNLEDHHB_01662 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MNLEDHHB_01663 2.58e-163 - - - F - - - NUDIX domain
MNLEDHHB_01664 1.37e-94 - - - S - - - Iron-sulphur cluster biosynthesis
MNLEDHHB_01665 2.4e-126 - - - S - - - Uncharacterised protein family (UPF0236)
MNLEDHHB_01666 3.66e-292 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MNLEDHHB_01667 1.09e-169 - - - K - - - helix_turn_helix, mercury resistance
MNLEDHHB_01668 1.09e-256 - - - S ko:K07133 - ko00000 cog cog1373
MNLEDHHB_01669 1.13e-290 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MNLEDHHB_01670 3.03e-187 - - - S - - - haloacid dehalogenase-like hydrolase
MNLEDHHB_01671 1.48e-200 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
MNLEDHHB_01672 9.83e-164 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
MNLEDHHB_01673 1.59e-290 - - - S ko:K06921 - ko00000 Archaea bacterial proteins of unknown function
MNLEDHHB_01674 1.17e-118 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
MNLEDHHB_01675 5.41e-123 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase homologues.
MNLEDHHB_01676 7.93e-36 - - - - - - - -
MNLEDHHB_01677 0.0 - - - S - - - O-antigen ligase like membrane protein
MNLEDHHB_01678 1.26e-138 - - - L - - - Belongs to the 'phage' integrase family
MNLEDHHB_01679 9.06e-60 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MNLEDHHB_01680 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MNLEDHHB_01681 2.68e-238 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MNLEDHHB_01682 4.17e-136 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
MNLEDHHB_01683 3.2e-252 degS 2.7.13.3 - F ko:K07683,ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
MNLEDHHB_01684 9.57e-136 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein domain
MNLEDHHB_01685 2.91e-47 - - - C - - - FMN_bind
MNLEDHHB_01686 2.6e-107 - - - - - - - -
MNLEDHHB_01687 1.04e-220 iunH 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
MNLEDHHB_01688 7.61e-217 ydhF - - S - - - Aldo keto reductase
MNLEDHHB_01689 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MNLEDHHB_01690 3.24e-157 - - - K ko:K03492 - ko00000,ko03000 UTRA domain
MNLEDHHB_01691 9.69e-72 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MNLEDHHB_01692 4.27e-77 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
MNLEDHHB_01693 1.92e-12 - - - - - - - -
MNLEDHHB_01694 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MNLEDHHB_01695 6.05e-56 - - - U ko:K05340 - ko00000,ko02000 sugar transport
MNLEDHHB_01696 6.24e-11 - - - - - - - -
MNLEDHHB_01697 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
MNLEDHHB_01698 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MNLEDHHB_01699 2.37e-184 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
MNLEDHHB_01700 1.05e-112 - - - - - - - -
MNLEDHHB_01701 2.6e-96 - - - - - - - -
MNLEDHHB_01702 4.02e-204 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
MNLEDHHB_01703 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MNLEDHHB_01704 9.87e-88 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
MNLEDHHB_01705 1.88e-58 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
MNLEDHHB_01706 3.5e-74 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
MNLEDHHB_01707 3.65e-313 ynbB - - P - - - aluminum resistance
MNLEDHHB_01708 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
MNLEDHHB_01709 0.0 - - - E - - - Amino acid permease
MNLEDHHB_01710 1.42e-60 - - - C - - - Pyridoxamine 5'-phosphate oxidase
MNLEDHHB_01711 2.82e-38 - - - C - - - Pyridoxamine 5'-phosphate oxidase
MNLEDHHB_01712 2.08e-84 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MNLEDHHB_01713 8.4e-85 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MNLEDHHB_01714 4.15e-192 - - - L - - - Phage integrase, N-terminal SAM-like domain
MNLEDHHB_01715 1.71e-75 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MNLEDHHB_01716 5.22e-156 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
MNLEDHHB_01717 2.03e-155 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
MNLEDHHB_01718 1.23e-174 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MNLEDHHB_01719 1.61e-294 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
MNLEDHHB_01720 1.98e-70 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
MNLEDHHB_01721 2.21e-62 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MNLEDHHB_01722 1.92e-254 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MNLEDHHB_01723 1.32e-133 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MNLEDHHB_01724 5.3e-152 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
MNLEDHHB_01725 2.54e-42 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MNLEDHHB_01726 3.06e-162 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MNLEDHHB_01727 3.93e-94 - - - K - - - Transcriptional regulator, MarR family
MNLEDHHB_01728 7.31e-52 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MNLEDHHB_01729 8.66e-82 - - - L ko:K07484 - ko00000 Transposase IS66 family
MNLEDHHB_01730 2.05e-173 - - - L - - - Transposase and inactivated derivatives
MNLEDHHB_01731 5.15e-26 - - - S - - - Transposase C of IS166 homeodomain
MNLEDHHB_01732 1.35e-39 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
MNLEDHHB_01733 5e-32 - - - - - - - -
MNLEDHHB_01734 3.24e-219 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MNLEDHHB_01735 3.41e-299 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MNLEDHHB_01736 1.15e-116 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MNLEDHHB_01737 3.92e-217 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
MNLEDHHB_01738 1.42e-315 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MNLEDHHB_01739 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MNLEDHHB_01740 5.47e-198 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
MNLEDHHB_01741 3.02e-171 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MNLEDHHB_01742 1.84e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MNLEDHHB_01743 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
MNLEDHHB_01744 9.85e-49 yozE - - S - - - Belongs to the UPF0346 family
MNLEDHHB_01745 6.79e-190 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
MNLEDHHB_01746 5.77e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
MNLEDHHB_01747 1.26e-287 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MNLEDHHB_01748 7.21e-205 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MNLEDHHB_01749 5.61e-292 XK27_05225 - - S - - - Tetratricopeptide repeat protein
MNLEDHHB_01750 1.17e-56 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MNLEDHHB_01751 3.67e-312 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MNLEDHHB_01752 8.97e-274 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MNLEDHHB_01753 5.18e-149 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MNLEDHHB_01754 1.03e-57 - - - M - - - Lysin motif
MNLEDHHB_01755 7.28e-147 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MNLEDHHB_01756 3.14e-166 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MNLEDHHB_01757 6.71e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MNLEDHHB_01758 3e-168 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MNLEDHHB_01759 1.56e-78 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MNLEDHHB_01760 1.48e-216 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
MNLEDHHB_01761 1.42e-212 yitL - - S ko:K00243 - ko00000 S1 domain
MNLEDHHB_01762 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MNLEDHHB_01763 1.34e-233 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MNLEDHHB_01764 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MNLEDHHB_01765 1.21e-284 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
MNLEDHHB_01766 2.18e-132 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MNLEDHHB_01767 4.8e-143 - - - K - - - DNA-binding helix-turn-helix protein
MNLEDHHB_01768 5.26e-63 - - - K - - - Helix-turn-helix
MNLEDHHB_01769 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MNLEDHHB_01770 1.38e-146 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
MNLEDHHB_01771 9.01e-137 - - - - - - - -
MNLEDHHB_01772 5.05e-47 - - - - - - - -
MNLEDHHB_01773 2.29e-114 - - - S - - - GyrI-like small molecule binding domain
MNLEDHHB_01774 4.08e-43 - - - EGP - - - Major facilitator Superfamily
MNLEDHHB_01775 2.7e-56 - - - EGP - - - Major Facilitator Superfamily
MNLEDHHB_01776 2.57e-109 - - - K - - - Domain of unknown function (DUF1836)
MNLEDHHB_01777 3.71e-199 yitS - - S - - - EDD domain protein, DegV family
MNLEDHHB_01778 1.01e-67 - - - - - - - -
MNLEDHHB_01779 8.74e-57 - - - - - - - -
MNLEDHHB_01780 2.99e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
MNLEDHHB_01781 1.59e-94 - - - L - - - Transposase and inactivated derivatives, IS30 family
MNLEDHHB_01782 6.57e-97 - - - L - - - Transposase and inactivated derivatives, IS30 family
MNLEDHHB_01783 0.000255 - - - S - - - CsbD-like
MNLEDHHB_01784 5.32e-35 - - - S - - - Transglycosylase associated protein
MNLEDHHB_01785 4.71e-304 - - - I - - - Protein of unknown function (DUF2974)
MNLEDHHB_01786 2.55e-154 - - - S ko:K07507 - ko00000,ko02000 MgtC family
MNLEDHHB_01788 1.88e-34 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
MNLEDHHB_01789 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MNLEDHHB_01790 2.57e-64 - - - S - - - Cupredoxin-like domain
MNLEDHHB_01791 2e-82 - - - S - - - Cupredoxin-like domain
MNLEDHHB_01792 8.25e-101 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
MNLEDHHB_01793 4.82e-46 - - - - - - - -
MNLEDHHB_01794 2.46e-289 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MNLEDHHB_01796 1.37e-214 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MNLEDHHB_01799 5.04e-278 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MNLEDHHB_01800 0.0 mdr - - EGP - - - Major Facilitator
MNLEDHHB_01801 6.98e-185 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MNLEDHHB_01802 5.79e-217 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
MNLEDHHB_01803 0.0 - - - S - - - membrane
MNLEDHHB_01804 2.15e-72 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MNLEDHHB_01805 2.22e-157 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MNLEDHHB_01806 6.4e-131 - - - G - - - Antibiotic biosynthesis monooxygenase
MNLEDHHB_01807 1.55e-18 - - - - - - - -
MNLEDHHB_01808 2.13e-77 - - - - - - - -
MNLEDHHB_01809 6.68e-136 - - - K - - - LysR substrate binding domain
MNLEDHHB_01810 6.5e-26 - - - - - - - -
MNLEDHHB_01811 2.29e-273 - - - S - - - Sterol carrier protein domain
MNLEDHHB_01812 2.32e-71 - - - - - - - -
MNLEDHHB_01813 1.07e-104 - - - K - - - Acetyltransferase (GNAT) domain
MNLEDHHB_01815 9.45e-99 codA - - F - - - Cytidine and deoxycytidylate deaminase zinc-binding region
MNLEDHHB_01816 1.51e-185 - - - F - - - Phosphorylase superfamily
MNLEDHHB_01817 3.74e-154 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
MNLEDHHB_01818 4.45e-83 - - - - - - - -
MNLEDHHB_01819 2.93e-71 - - - S - - - Domain of unknown function (DUF5067)
MNLEDHHB_01820 5.31e-58 - - - - - - - -
MNLEDHHB_01821 2.57e-71 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
MNLEDHHB_01822 2.04e-56 - - - S - - - Enterocin A Immunity
MNLEDHHB_01823 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MNLEDHHB_01824 1.39e-96 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
MNLEDHHB_01825 2.56e-250 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MNLEDHHB_01826 5.98e-63 - - - S - - - CAAX protease self-immunity
MNLEDHHB_01827 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
MNLEDHHB_01828 7.77e-36 - - - - - - - -
MNLEDHHB_01829 1.13e-21 - - - - - - - -
MNLEDHHB_01830 8.68e-44 - - - - - - - -
MNLEDHHB_01831 1.95e-45 - - - S - - - Enterocin A Immunity
MNLEDHHB_01832 0.0 - - - E - - - Amino acid permease
MNLEDHHB_01834 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MNLEDHHB_01835 9.51e-119 - - - S - - - VanZ like family
MNLEDHHB_01836 2.3e-170 yebC - - K - - - Transcriptional regulatory protein
MNLEDHHB_01837 1.33e-226 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
MNLEDHHB_01838 1.86e-222 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
MNLEDHHB_01839 2.93e-64 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
MNLEDHHB_01840 2.04e-95 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
MNLEDHHB_01841 1.18e-55 - - - - - - - -
MNLEDHHB_01842 9.9e-105 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
MNLEDHHB_01843 4.89e-238 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
MNLEDHHB_01844 3.05e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MNLEDHHB_01846 2.64e-50 - - - M - - - Protein of unknown function (DUF3737)
MNLEDHHB_01847 9.31e-40 - - - M - - - Protein of unknown function (DUF3737)
MNLEDHHB_01848 1.35e-284 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MNLEDHHB_01849 5.98e-217 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MNLEDHHB_01850 8.14e-80 - - - S - - - SdpI/YhfL protein family
MNLEDHHB_01851 4.46e-167 - - - K - - - Transcriptional regulatory protein, C terminal
MNLEDHHB_01852 0.0 yclK - - T - - - Histidine kinase
MNLEDHHB_01853 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MNLEDHHB_01854 1.3e-139 vanZ - - V - - - VanZ like family
MNLEDHHB_01855 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MNLEDHHB_01856 1.89e-19 - - - EGP - - - Major Facilitator
MNLEDHHB_01857 3.42e-219 - - - EGP - - - Major Facilitator
MNLEDHHB_01858 2.36e-247 ampC - - V - - - Beta-lactamase
MNLEDHHB_01861 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
MNLEDHHB_01862 4.94e-146 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MNLEDHHB_01863 7.36e-234 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MNLEDHHB_01864 8.44e-201 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MNLEDHHB_01865 3.08e-241 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MNLEDHHB_01866 1.84e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MNLEDHHB_01867 4.82e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MNLEDHHB_01868 4.83e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MNLEDHHB_01869 4.97e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MNLEDHHB_01870 1.27e-117 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MNLEDHHB_01871 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MNLEDHHB_01872 8.2e-219 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MNLEDHHB_01873 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MNLEDHHB_01874 4.95e-93 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MNLEDHHB_01875 4.22e-41 - - - S - - - Protein of unknown function (DUF1146)
MNLEDHHB_01876 7.96e-226 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
MNLEDHHB_01877 4.39e-66 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MNLEDHHB_01878 8.85e-47 - - - S - - - Protein of unknown function (DUF2969)
MNLEDHHB_01879 5.87e-276 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MNLEDHHB_01880 9.45e-104 uspA - - T - - - universal stress protein
MNLEDHHB_01881 4.53e-55 - - - - - - - -
MNLEDHHB_01882 6.14e-105 - - - S - - - Protein of unknown function (DUF1694)
MNLEDHHB_01883 2.95e-140 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MNLEDHHB_01884 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MNLEDHHB_01885 1.23e-276 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MNLEDHHB_01886 7.99e-294 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MNLEDHHB_01887 1.71e-176 - - - K - - - Helix-turn-helix domain
MNLEDHHB_01888 5.21e-164 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MNLEDHHB_01889 2.95e-21 - - - K - - - Helix-turn-helix domain
MNLEDHHB_01890 1.89e-74 - - - - - - - -
MNLEDHHB_01891 9.54e-208 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MNLEDHHB_01892 1.2e-41 yebC - - M - - - Membrane
MNLEDHHB_01893 8.57e-13 - - - - - - - -
MNLEDHHB_01894 2.81e-37 - - - - - - - -
MNLEDHHB_01895 3.95e-41 - - - S - - - HicB family
MNLEDHHB_01896 9.53e-23 - - - S - - - HicA toxin of bacterial toxin-antitoxin,
MNLEDHHB_01899 1.76e-109 - - - S - - - COG NOG38524 non supervised orthologous group
MNLEDHHB_01900 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MNLEDHHB_01901 2.81e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MNLEDHHB_01902 7.28e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MNLEDHHB_01903 1.56e-156 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
MNLEDHHB_01904 1.36e-267 - - - C - - - Glycerophosphoryl diester phosphodiesterase family
MNLEDHHB_01905 1.2e-87 - - - S - - - GtrA-like protein
MNLEDHHB_01906 3.62e-216 yfdH - GT2 M ko:K12999,ko:K20534 - ko00000,ko01000,ko01003,ko01005,ko02000 Glycosyltransferase like family 2
MNLEDHHB_01907 4.34e-36 - - - S - - - Bacterial membrane protein, YfhO
MNLEDHHB_01908 8.78e-21 - - - S - - - Bacterial membrane protein, YfhO
MNLEDHHB_01909 1.51e-65 - - - S - - - Bacterial membrane protein, YfhO
MNLEDHHB_01910 1.9e-11 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
MNLEDHHB_01911 2.09e-64 - - - EGP - - - Major facilitator Superfamily
MNLEDHHB_01912 9.67e-153 - - - EGP - - - Major facilitator Superfamily
MNLEDHHB_01913 1.48e-131 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
MNLEDHHB_01915 2.88e-119 - - - - - - - -
MNLEDHHB_01918 2.37e-271 - - - - - - - -
MNLEDHHB_01919 1.49e-157 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
MNLEDHHB_01920 3.41e-80 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
MNLEDHHB_01921 3.99e-42 repA - - S - - - Replication initiator protein A
MNLEDHHB_01923 1.31e-10 - - - - - - - -
MNLEDHHB_01924 3.06e-74 - - - - - - - -
MNLEDHHB_01925 9.47e-20 - - - - - - - -
MNLEDHHB_01927 1.38e-115 - - - - - - - -
MNLEDHHB_01928 5.83e-100 - - - - - - - -
MNLEDHHB_01929 1.84e-197 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
MNLEDHHB_01930 4.63e-88 - - - - - - - -
MNLEDHHB_01931 1.78e-42 - - - - - - - -
MNLEDHHB_01932 3.36e-91 - - - S - - - Iron-sulphur cluster biosynthesis
MNLEDHHB_01933 1.44e-166 yheS_2 - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
MNLEDHHB_01934 5.86e-39 yheS_2 - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
MNLEDHHB_01935 2.58e-108 - - - - - - - -
MNLEDHHB_01936 6.82e-74 - - - - - - - -
MNLEDHHB_01937 2.19e-307 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MNLEDHHB_01938 1.38e-313 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MNLEDHHB_01939 4.71e-233 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MNLEDHHB_01941 7.45e-258 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
MNLEDHHB_01942 3.6e-242 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
MNLEDHHB_01943 1.35e-301 - - - E - - - amino acid
MNLEDHHB_01944 6.39e-177 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
MNLEDHHB_01945 1.24e-312 yifK - - E ko:K03293 - ko00000 Amino acid permease
MNLEDHHB_01946 2.93e-299 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MNLEDHHB_01947 3.65e-156 - - - - - - - -
MNLEDHHB_01948 9.86e-153 sipS3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MNLEDHHB_01949 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 AAA domain (Cdc48 subfamily)
MNLEDHHB_01950 2.75e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MNLEDHHB_01951 6.21e-270 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MNLEDHHB_01952 1.48e-159 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MNLEDHHB_01953 1.38e-73 - - - M ko:K02004 - ko00000,ko00002,ko02000 Membrane
MNLEDHHB_01954 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MNLEDHHB_01955 3.96e-49 - - - - - - - -
MNLEDHHB_01956 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MNLEDHHB_01957 6.7e-200 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MNLEDHHB_01958 1.75e-156 - - - S - - - Protein of unknown function (DUF975)
MNLEDHHB_01959 2.66e-64 - - - - - - - -
MNLEDHHB_01960 6.93e-39 - - - - - - - -
MNLEDHHB_01961 7.99e-37 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MNLEDHHB_01962 1.37e-56 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MNLEDHHB_01963 1.87e-11 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MNLEDHHB_01965 2.66e-221 pbpX2 - - V - - - Beta-lactamase
MNLEDHHB_01966 1.05e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MNLEDHHB_01967 1e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MNLEDHHB_01968 2.95e-304 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
MNLEDHHB_01969 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MNLEDHHB_01970 3.2e-27 - - - S - - - D-Ala-teichoic acid biosynthesis protein
MNLEDHHB_01971 2.34e-66 - - - - - - - -
MNLEDHHB_01972 3.66e-274 - - - S - - - Membrane
MNLEDHHB_01973 1.69e-107 ykuL - - S - - - (CBS) domain
MNLEDHHB_01974 0.0 cadA - - P - - - P-type ATPase
MNLEDHHB_01975 1.5e-258 napA - - P - - - Sodium/hydrogen exchanger family
MNLEDHHB_01976 9e-66 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
MNLEDHHB_01977 1.37e-63 yoeB - - S ko:K19158 - ko00000,ko01000,ko02048 YoeB-like toxin of bacterial type II toxin-antitoxin system
MNLEDHHB_01978 1.03e-101 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
MNLEDHHB_01979 9.71e-224 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
MNLEDHHB_01980 7e-103 - - - S - - - Putative adhesin
MNLEDHHB_01981 6.17e-198 mutR - - K - - - Helix-turn-helix XRE-family like proteins
MNLEDHHB_01982 1.77e-61 - - - - - - - -
MNLEDHHB_01983 2.14e-104 - - - K - - - LysR substrate binding domain
MNLEDHHB_01984 3.57e-160 - - - C - - - FAD binding domain
MNLEDHHB_01985 7.46e-72 - - - C - - - FAD binding domain
MNLEDHHB_01986 1.09e-141 - - - K - - - Transcriptional regulator, LysR family
MNLEDHHB_01987 5.52e-128 - - - K - - - LysR substrate binding domain
MNLEDHHB_01988 2.89e-52 - - - K - - - LysR substrate binding domain
MNLEDHHB_01992 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative DNA-binding domain
MNLEDHHB_01993 3e-308 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
MNLEDHHB_01994 6.05e-128 - - - - - - - -
MNLEDHHB_01995 3.15e-99 - - - - - - - -
MNLEDHHB_01996 1.43e-262 - - - G - - - Major Facilitator Superfamily
MNLEDHHB_01997 4.67e-163 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
MNLEDHHB_01998 2.23e-150 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
MNLEDHHB_01999 8.04e-228 - - - L - - - COG3547 Transposase and inactivated derivatives

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)