ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MFFGAFPN_00001 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MFFGAFPN_00002 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MFFGAFPN_00003 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
MFFGAFPN_00004 3.2e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MFFGAFPN_00005 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
MFFGAFPN_00006 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MFFGAFPN_00007 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MFFGAFPN_00008 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
MFFGAFPN_00011 2.14e-232 yaaC - - S - - - YaaC-like Protein
MFFGAFPN_00012 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MFFGAFPN_00013 3.75e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MFFGAFPN_00014 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MFFGAFPN_00015 3.34e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MFFGAFPN_00016 9.79e-296 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MFFGAFPN_00018 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
MFFGAFPN_00019 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
MFFGAFPN_00020 2.57e-276 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
MFFGAFPN_00021 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
MFFGAFPN_00022 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MFFGAFPN_00023 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MFFGAFPN_00024 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MFFGAFPN_00025 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MFFGAFPN_00026 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
MFFGAFPN_00027 6.2e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
MFFGAFPN_00028 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
MFFGAFPN_00031 3.67e-41 csfB - - S - - - Inhibitor of sigma-G Gin
MFFGAFPN_00032 3.83e-132 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MFFGAFPN_00033 8.37e-259 yaaN - - P - - - Belongs to the TelA family
MFFGAFPN_00034 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
MFFGAFPN_00035 2.22e-144 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MFFGAFPN_00036 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
MFFGAFPN_00037 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
MFFGAFPN_00038 2.42e-236 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MFFGAFPN_00039 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
MFFGAFPN_00040 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
MFFGAFPN_00041 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
MFFGAFPN_00042 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
MFFGAFPN_00043 1.71e-206 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MFFGAFPN_00044 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
MFFGAFPN_00045 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MFFGAFPN_00046 6.89e-183 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
MFFGAFPN_00047 1.91e-283 yabE - - T - - - protein conserved in bacteria
MFFGAFPN_00048 1.43e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MFFGAFPN_00049 4.14e-198 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MFFGAFPN_00050 1.84e-197 yabG - - S ko:K06436 - ko00000 peptidase
MFFGAFPN_00051 5.32e-53 veg - - S - - - protein conserved in bacteria
MFFGAFPN_00052 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MFFGAFPN_00053 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MFFGAFPN_00054 1.64e-81 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
MFFGAFPN_00055 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MFFGAFPN_00056 1.05e-308 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MFFGAFPN_00057 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MFFGAFPN_00058 9.8e-135 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MFFGAFPN_00059 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MFFGAFPN_00060 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
MFFGAFPN_00061 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MFFGAFPN_00062 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
MFFGAFPN_00063 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MFFGAFPN_00064 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MFFGAFPN_00065 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MFFGAFPN_00066 1.91e-66 yabP - - S - - - Sporulation protein YabP
MFFGAFPN_00067 2.21e-139 yabQ - - S - - - spore cortex biosynthesis protein
MFFGAFPN_00068 1.2e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MFFGAFPN_00069 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
MFFGAFPN_00072 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
MFFGAFPN_00073 5.38e-166 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MFFGAFPN_00074 5.93e-237 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
MFFGAFPN_00075 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MFFGAFPN_00076 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
MFFGAFPN_00077 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MFFGAFPN_00078 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MFFGAFPN_00079 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MFFGAFPN_00080 3.17e-194 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
MFFGAFPN_00081 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MFFGAFPN_00082 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MFFGAFPN_00083 5.98e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
MFFGAFPN_00084 2.09e-212 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
MFFGAFPN_00085 3.32e-205 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MFFGAFPN_00086 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MFFGAFPN_00087 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MFFGAFPN_00088 1.81e-41 yazB - - K - - - transcriptional
MFFGAFPN_00089 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MFFGAFPN_00090 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MFFGAFPN_00091 1.95e-54 - - - S - - - COG NOG14552 non supervised orthologous group
MFFGAFPN_00101 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
MFFGAFPN_00102 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
MFFGAFPN_00103 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
MFFGAFPN_00104 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MFFGAFPN_00105 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
MFFGAFPN_00106 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MFFGAFPN_00107 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MFFGAFPN_00108 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
MFFGAFPN_00109 1.82e-162 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MFFGAFPN_00110 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MFFGAFPN_00111 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MFFGAFPN_00112 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
MFFGAFPN_00113 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MFFGAFPN_00114 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MFFGAFPN_00115 1.01e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MFFGAFPN_00116 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
MFFGAFPN_00117 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
MFFGAFPN_00118 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MFFGAFPN_00119 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MFFGAFPN_00120 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MFFGAFPN_00121 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MFFGAFPN_00122 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MFFGAFPN_00123 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MFFGAFPN_00124 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MFFGAFPN_00125 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFFGAFPN_00126 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFFGAFPN_00127 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
MFFGAFPN_00128 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MFFGAFPN_00129 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MFFGAFPN_00130 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MFFGAFPN_00131 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MFFGAFPN_00132 2.04e-227 ybaC - - S - - - Alpha/beta hydrolase family
MFFGAFPN_00133 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MFFGAFPN_00134 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MFFGAFPN_00135 7.98e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MFFGAFPN_00136 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MFFGAFPN_00137 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MFFGAFPN_00138 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MFFGAFPN_00139 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MFFGAFPN_00140 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MFFGAFPN_00141 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MFFGAFPN_00142 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MFFGAFPN_00143 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MFFGAFPN_00144 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MFFGAFPN_00145 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MFFGAFPN_00146 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MFFGAFPN_00147 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MFFGAFPN_00148 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MFFGAFPN_00149 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MFFGAFPN_00150 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MFFGAFPN_00151 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MFFGAFPN_00152 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MFFGAFPN_00153 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MFFGAFPN_00154 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MFFGAFPN_00155 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MFFGAFPN_00156 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
MFFGAFPN_00157 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MFFGAFPN_00158 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MFFGAFPN_00159 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MFFGAFPN_00160 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MFFGAFPN_00161 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFFGAFPN_00162 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MFFGAFPN_00163 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MFFGAFPN_00164 4.47e-196 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MFFGAFPN_00165 3.23e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MFFGAFPN_00166 6.15e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MFFGAFPN_00167 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MFFGAFPN_00168 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MFFGAFPN_00169 2.92e-184 ybaJ - - Q - - - Methyltransferase domain
MFFGAFPN_00170 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
MFFGAFPN_00171 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MFFGAFPN_00172 4.47e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MFFGAFPN_00173 1.04e-122 gerD - - - ko:K06294 - ko00000 -
MFFGAFPN_00174 2.42e-132 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
MFFGAFPN_00175 2.49e-180 pdaB - - G - - - Polysaccharide deacetylase
MFFGAFPN_00176 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
MFFGAFPN_00179 3.21e-38 - - - L - - - Phage integrase family
MFFGAFPN_00185 1.06e-69 - - - K - - - DNA binding
MFFGAFPN_00186 9.51e-157 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
MFFGAFPN_00187 2.65e-21 - - - - - - - -
MFFGAFPN_00190 1.86e-23 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
MFFGAFPN_00192 1.4e-54 - - - - - - - -
MFFGAFPN_00193 5.31e-48 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
MFFGAFPN_00194 2.75e-119 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
MFFGAFPN_00196 2.4e-76 - - - - - - - -
MFFGAFPN_00201 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
MFFGAFPN_00202 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
MFFGAFPN_00203 2.61e-316 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
MFFGAFPN_00205 5.36e-203 ybaS - - S - - - Na -dependent transporter
MFFGAFPN_00206 5.87e-177 ybbA - - S ko:K07017 - ko00000 Putative esterase
MFFGAFPN_00207 2.37e-226 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFFGAFPN_00208 2.88e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFFGAFPN_00209 1.26e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
MFFGAFPN_00210 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
MFFGAFPN_00211 8.14e-303 ybbC - - S - - - protein conserved in bacteria
MFFGAFPN_00212 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
MFFGAFPN_00213 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
MFFGAFPN_00214 2.09e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MFFGAFPN_00215 5.43e-194 ybbH - - K - - - transcriptional
MFFGAFPN_00216 1.64e-210 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MFFGAFPN_00217 3.13e-114 ybbJ - - J - - - acetyltransferase
MFFGAFPN_00218 4.19e-101 ybbK - - S - - - Protein of unknown function (DUF523)
MFFGAFPN_00224 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MFFGAFPN_00225 2.16e-149 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MFFGAFPN_00226 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MFFGAFPN_00227 3.41e-291 ybbR - - S - - - protein conserved in bacteria
MFFGAFPN_00228 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MFFGAFPN_00229 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MFFGAFPN_00230 7.64e-220 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MFFGAFPN_00231 1.07e-155 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
MFFGAFPN_00232 4.49e-130 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MFFGAFPN_00233 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MFFGAFPN_00234 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
MFFGAFPN_00235 1.34e-120 ybcF - - P - - - carbonic anhydrase
MFFGAFPN_00236 1.6e-63 - - - - - - - -
MFFGAFPN_00237 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
MFFGAFPN_00238 9.45e-67 - - - K - - - Helix-turn-helix domain
MFFGAFPN_00239 7.69e-257 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
MFFGAFPN_00240 7.97e-73 - - - - - - - -
MFFGAFPN_00241 5.45e-231 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MFFGAFPN_00242 1.39e-157 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
MFFGAFPN_00243 3.39e-220 - - - T - - - His Kinase A (phospho-acceptor) domain
MFFGAFPN_00245 1.96e-178 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
MFFGAFPN_00246 1.28e-193 ybdN - - - - - - -
MFFGAFPN_00247 1.33e-275 ybdO - - S - - - Domain of unknown function (DUF4885)
MFFGAFPN_00248 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MFFGAFPN_00249 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
MFFGAFPN_00250 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
MFFGAFPN_00251 3.71e-193 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
MFFGAFPN_00252 2.67e-314 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
MFFGAFPN_00253 4.54e-54 ybyB - - - - - - -
MFFGAFPN_00254 0.0 ybeC - - E - - - amino acid
MFFGAFPN_00255 2.44e-211 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
MFFGAFPN_00256 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
MFFGAFPN_00257 1.02e-46 - - - S - - - Protein of unknown function (DUF2651)
MFFGAFPN_00258 4.29e-202 ybfA - - K - - - FR47-like protein
MFFGAFPN_00259 3.53e-286 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
MFFGAFPN_00261 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
MFFGAFPN_00262 3.05e-207 ybfH - - EG - - - EamA-like transporter family
MFFGAFPN_00263 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
MFFGAFPN_00264 1.32e-270 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MFFGAFPN_00265 1.44e-229 mpr - - M - - - Belongs to the peptidase S1B family
MFFGAFPN_00267 2.02e-216 - - - S - - - Alpha/beta hydrolase family
MFFGAFPN_00268 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MFFGAFPN_00269 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
MFFGAFPN_00270 4.33e-190 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MFFGAFPN_00271 1.58e-59 ybfN - - - - - - -
MFFGAFPN_00272 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
MFFGAFPN_00273 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MFFGAFPN_00274 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MFFGAFPN_00275 9.29e-169 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MFFGAFPN_00276 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
MFFGAFPN_00278 3.08e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MFFGAFPN_00279 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MFFGAFPN_00280 9.76e-229 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
MFFGAFPN_00281 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
MFFGAFPN_00282 9.16e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
MFFGAFPN_00283 3.55e-294 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFFGAFPN_00284 1.72e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
MFFGAFPN_00285 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
MFFGAFPN_00286 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MFFGAFPN_00287 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MFFGAFPN_00288 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
MFFGAFPN_00289 7.68e-160 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
MFFGAFPN_00290 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
MFFGAFPN_00291 1.55e-225 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
MFFGAFPN_00292 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
MFFGAFPN_00293 3.2e-216 eamA1 - - EG - - - spore germination
MFFGAFPN_00294 2.24e-161 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFFGAFPN_00295 3.75e-215 ycbM - - T - - - Histidine kinase
MFFGAFPN_00296 1.66e-216 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFGAFPN_00297 2.87e-148 - - - S - - - ABC-2 family transporter protein
MFFGAFPN_00298 1.82e-75 ycbP - - S - - - Protein of unknown function (DUF2512)
MFFGAFPN_00299 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
MFFGAFPN_00300 5.44e-174 ycbR - - T - - - vWA found in TerF C terminus
MFFGAFPN_00301 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
MFFGAFPN_00302 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MFFGAFPN_00303 3.09e-159 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MFFGAFPN_00304 1.2e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MFFGAFPN_00305 1.28e-254 ycbU - - E - - - Selenocysteine lyase
MFFGAFPN_00306 2.87e-308 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
MFFGAFPN_00307 1.04e-128 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
MFFGAFPN_00308 3.97e-256 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MFFGAFPN_00309 1.63e-146 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
MFFGAFPN_00310 1.14e-73 - - - S - - - RDD family
MFFGAFPN_00311 2.49e-255 yccF - - K ko:K07039 - ko00000 SEC-C motif
MFFGAFPN_00312 4.16e-211 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MFFGAFPN_00313 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MFFGAFPN_00314 2.2e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MFFGAFPN_00315 5.64e-257 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MFFGAFPN_00316 9.67e-222 yccK - - C - - - Aldo keto reductase
MFFGAFPN_00317 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
MFFGAFPN_00318 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MFFGAFPN_00319 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MFFGAFPN_00320 2.65e-123 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
MFFGAFPN_00321 2.86e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
MFFGAFPN_00322 6.85e-180 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
MFFGAFPN_00323 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MFFGAFPN_00324 2.27e-220 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MFFGAFPN_00325 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MFFGAFPN_00326 1.88e-172 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MFFGAFPN_00327 1.91e-234 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MFFGAFPN_00328 2.17e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
MFFGAFPN_00329 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
MFFGAFPN_00330 5.8e-137 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
MFFGAFPN_00331 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
MFFGAFPN_00332 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
MFFGAFPN_00333 2.96e-245 yceH - - P - - - Belongs to the TelA family
MFFGAFPN_00334 2.7e-278 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
MFFGAFPN_00335 1.07e-263 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
MFFGAFPN_00336 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MFFGAFPN_00337 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
MFFGAFPN_00338 6.02e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MFFGAFPN_00339 1.16e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MFFGAFPN_00340 1.97e-276 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
MFFGAFPN_00341 0.0 ycgA - - S - - - Membrane
MFFGAFPN_00342 6.39e-104 ycgB - - - - - - -
MFFGAFPN_00343 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
MFFGAFPN_00344 2.93e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MFFGAFPN_00345 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MFFGAFPN_00346 0.0 mdr - - EGP - - - the major facilitator superfamily
MFFGAFPN_00347 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
MFFGAFPN_00348 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
MFFGAFPN_00349 1.99e-190 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
MFFGAFPN_00350 1.86e-316 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MFFGAFPN_00351 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
MFFGAFPN_00352 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MFFGAFPN_00353 2.44e-136 tmrB - - S - - - AAA domain
MFFGAFPN_00355 1.74e-135 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MFFGAFPN_00356 3.56e-184 - - - Q - - - ubiE/COQ5 methyltransferase family
MFFGAFPN_00357 3.97e-228 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
MFFGAFPN_00358 1.29e-230 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
MFFGAFPN_00359 7.76e-187 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
MFFGAFPN_00360 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
MFFGAFPN_00361 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
MFFGAFPN_00362 2.64e-316 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MFFGAFPN_00363 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
MFFGAFPN_00364 2.47e-191 ycgQ - - S ko:K08986 - ko00000 membrane
MFFGAFPN_00365 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
MFFGAFPN_00366 3.44e-202 ycgS - - I - - - alpha/beta hydrolase fold
MFFGAFPN_00367 8.53e-245 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MFFGAFPN_00368 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
MFFGAFPN_00369 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
MFFGAFPN_00370 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MFFGAFPN_00371 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MFFGAFPN_00372 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
MFFGAFPN_00373 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
MFFGAFPN_00374 1.08e-215 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
MFFGAFPN_00375 8.56e-140 - - - M - - - ErfK YbiS YcfS YnhG
MFFGAFPN_00376 3.76e-288 yciC - - S - - - GTPases (G3E family)
MFFGAFPN_00377 9.69e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MFFGAFPN_00378 7.26e-185 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MFFGAFPN_00380 2.24e-96 yckC - - S - - - membrane
MFFGAFPN_00381 1.01e-68 yckD - - S - - - Protein of unknown function (DUF2680)
MFFGAFPN_00382 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MFFGAFPN_00383 4.78e-91 nin - - S - - - Competence protein J (ComJ)
MFFGAFPN_00384 1e-93 nucA - - M - - - Deoxyribonuclease NucA/NucB
MFFGAFPN_00385 6.52e-269 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MFFGAFPN_00386 1.13e-126 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
MFFGAFPN_00387 5.63e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
MFFGAFPN_00388 2.47e-85 hxlR - - K - - - transcriptional
MFFGAFPN_00389 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFFGAFPN_00390 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFFGAFPN_00391 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
MFFGAFPN_00392 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
MFFGAFPN_00393 2.18e-288 - - - EGP - - - Major Facilitator Superfamily
MFFGAFPN_00394 1.94e-118 - - - S - - - YcxB-like protein
MFFGAFPN_00395 6.59e-205 ycxC - - EG - - - EamA-like transporter family
MFFGAFPN_00396 0.0 ycxD - - K - - - GntR family transcriptional regulator
MFFGAFPN_00397 4.76e-145 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
MFFGAFPN_00398 6.13e-148 yczE - - S ko:K07149 - ko00000 membrane
MFFGAFPN_00399 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MFFGAFPN_00400 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MFFGAFPN_00401 1.23e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MFFGAFPN_00402 8.83e-208 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
MFFGAFPN_00403 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MFFGAFPN_00404 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MFFGAFPN_00405 2.83e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
MFFGAFPN_00406 1.7e-106 yclD - - - - - - -
MFFGAFPN_00407 6.7e-203 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
MFFGAFPN_00408 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
MFFGAFPN_00409 0.0 yclG - - M - - - Pectate lyase superfamily protein
MFFGAFPN_00411 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
MFFGAFPN_00412 8.35e-297 gerKC - - S ko:K06297 - ko00000 spore germination
MFFGAFPN_00413 4.63e-254 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
MFFGAFPN_00414 2.79e-154 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MFFGAFPN_00415 9.52e-277 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
MFFGAFPN_00416 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFFGAFPN_00417 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MFFGAFPN_00418 7.15e-104 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MFFGAFPN_00420 1.58e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MFFGAFPN_00421 6.5e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MFFGAFPN_00422 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MFFGAFPN_00423 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFFGAFPN_00424 2.6e-208 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFFGAFPN_00425 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MFFGAFPN_00426 5.47e-211 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
MFFGAFPN_00427 0.0 ycnB - - EGP - - - the major facilitator superfamily
MFFGAFPN_00428 5.87e-198 ycnC - - K - - - Transcriptional regulator
MFFGAFPN_00429 3.52e-173 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
MFFGAFPN_00430 1.68e-60 ycnE - - S - - - Monooxygenase
MFFGAFPN_00431 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MFFGAFPN_00432 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MFFGAFPN_00433 9.76e-313 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MFFGAFPN_00434 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MFFGAFPN_00435 3.37e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
MFFGAFPN_00436 8.38e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFFGAFPN_00437 1.63e-133 ycnI - - S - - - protein conserved in bacteria
MFFGAFPN_00438 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
MFFGAFPN_00439 2.88e-136 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MFFGAFPN_00440 9.44e-75 - - - - - - - -
MFFGAFPN_00441 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
MFFGAFPN_00442 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MFFGAFPN_00443 5.13e-267 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
MFFGAFPN_00444 9.72e-255 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
MFFGAFPN_00446 1.25e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MFFGAFPN_00447 1.92e-140 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
MFFGAFPN_00448 9.34e-88 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
MFFGAFPN_00450 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MFFGAFPN_00451 4.46e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
MFFGAFPN_00452 2.78e-273 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
MFFGAFPN_00453 7e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
MFFGAFPN_00454 4.84e-171 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
MFFGAFPN_00455 5.72e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
MFFGAFPN_00456 1.55e-170 kipR - - K - - - Transcriptional regulator
MFFGAFPN_00457 9.86e-153 ycsK - - E - - - anatomical structure formation involved in morphogenesis
MFFGAFPN_00459 8.97e-65 yczJ - - S - - - biosynthesis
MFFGAFPN_00460 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
MFFGAFPN_00461 1.27e-221 ycsN - - S - - - Oxidoreductase
MFFGAFPN_00462 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
MFFGAFPN_00463 0.0 ydaB - - IQ - - - acyl-CoA ligase
MFFGAFPN_00464 1e-127 ydaC - - Q - - - Methyltransferase domain
MFFGAFPN_00465 6.21e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFFGAFPN_00466 2.75e-125 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
MFFGAFPN_00467 3.82e-133 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MFFGAFPN_00468 5.24e-101 ydaG - - S - - - general stress protein
MFFGAFPN_00469 2.65e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MFFGAFPN_00470 5.19e-60 ydzA - - EGP - - - Domain of unknown function (DUF3817)
MFFGAFPN_00471 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
MFFGAFPN_00472 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MFFGAFPN_00473 1.71e-264 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
MFFGAFPN_00474 6.34e-193 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
MFFGAFPN_00475 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
MFFGAFPN_00476 1.93e-304 ydaM - - M - - - Glycosyl transferase family group 2
MFFGAFPN_00477 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
MFFGAFPN_00478 0.0 ydaO - - E - - - amino acid
MFFGAFPN_00479 1.47e-100 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
MFFGAFPN_00480 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MFFGAFPN_00482 1.84e-34 - - - - - - - -
MFFGAFPN_00483 2.18e-90 sdpB - - S - - - Protein conserved in bacteria
MFFGAFPN_00485 2.14e-53 - - - - - - - -
MFFGAFPN_00486 7.87e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MFFGAFPN_00487 1.67e-42 ydaS - - S - - - membrane
MFFGAFPN_00488 1.85e-99 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
MFFGAFPN_00489 1.75e-189 ydbA - - P - - - EcsC protein family
MFFGAFPN_00490 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
MFFGAFPN_00491 7.58e-79 ydbB - - G - - - Cupin domain
MFFGAFPN_00492 2.58e-82 ydbC - - S - - - Domain of unknown function (DUF4937
MFFGAFPN_00493 3.71e-196 ydbD - - P ko:K07217 - ko00000 Catalase
MFFGAFPN_00494 2.47e-251 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MFFGAFPN_00495 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MFFGAFPN_00496 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
MFFGAFPN_00497 8.93e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MFFGAFPN_00498 3.25e-231 ydbI - - S - - - AI-2E family transporter
MFFGAFPN_00500 3.23e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFGAFPN_00501 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MFFGAFPN_00502 9.32e-70 ydbL - - - - - - -
MFFGAFPN_00503 1.76e-278 ydbM - - I - - - acyl-CoA dehydrogenase
MFFGAFPN_00504 1.49e-26 - - - S - - - Fur-regulated basic protein B
MFFGAFPN_00506 5.48e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MFFGAFPN_00507 4.19e-75 ydbP - - CO - - - Thioredoxin
MFFGAFPN_00508 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MFFGAFPN_00509 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MFFGAFPN_00510 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MFFGAFPN_00511 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
MFFGAFPN_00512 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
MFFGAFPN_00513 2.96e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
MFFGAFPN_00514 1.6e-77 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MFFGAFPN_00515 1.56e-232 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
MFFGAFPN_00516 1.7e-280 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MFFGAFPN_00517 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MFFGAFPN_00518 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
MFFGAFPN_00519 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
MFFGAFPN_00520 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
MFFGAFPN_00521 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MFFGAFPN_00522 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
MFFGAFPN_00523 1.62e-69 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
MFFGAFPN_00524 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MFFGAFPN_00525 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFFGAFPN_00526 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
MFFGAFPN_00530 1.32e-106 ydcG - - S - - - EVE domain
MFFGAFPN_00531 1.26e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MFFGAFPN_00532 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
MFFGAFPN_00533 3.74e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MFFGAFPN_00542 1.04e-11 - - - S - - - SMI1 / KNR4 family
MFFGAFPN_00543 9.99e-59 - - - - - - - -
MFFGAFPN_00544 2.68e-177 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MFFGAFPN_00545 1.8e-45 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
MFFGAFPN_00546 1.54e-55 - - - - - - - -
MFFGAFPN_00547 1.59e-243 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
MFFGAFPN_00548 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
MFFGAFPN_00549 1.48e-46 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
MFFGAFPN_00550 2.79e-181 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MFFGAFPN_00551 9.24e-211 - - - K - - - AraC-like ligand binding domain
MFFGAFPN_00552 2.27e-220 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MFFGAFPN_00553 3.21e-210 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
MFFGAFPN_00554 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MFFGAFPN_00555 3.8e-277 ydeG - - EGP - - - Major facilitator superfamily
MFFGAFPN_00556 1.86e-69 ydeH - - - - - - -
MFFGAFPN_00557 6.99e-136 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
MFFGAFPN_00558 1.37e-138 - - - - - - - -
MFFGAFPN_00559 7.7e-18 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
MFFGAFPN_00560 4.22e-111 - - - K - - - Transcriptional regulator C-terminal region
MFFGAFPN_00561 1.05e-193 ydeK - - EG - - - -transporter
MFFGAFPN_00562 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MFFGAFPN_00563 3.68e-97 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
MFFGAFPN_00564 2.88e-136 - - - S ko:K07002 - ko00000 Serine hydrolase
MFFGAFPN_00565 5.22e-75 - - - K - - - HxlR-like helix-turn-helix
MFFGAFPN_00566 1.96e-195 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MFFGAFPN_00567 5.03e-91 ydeP - - K - - - Transcriptional regulator
MFFGAFPN_00568 6.98e-142 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
MFFGAFPN_00569 1.61e-256 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
MFFGAFPN_00570 1.78e-134 ydeS - - K - - - Transcriptional regulator
MFFGAFPN_00571 2.11e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
MFFGAFPN_00572 1.06e-295 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MFFGAFPN_00573 3.28e-190 - - - J - - - GNAT acetyltransferase
MFFGAFPN_00574 9.76e-204 - - - EG - - - EamA-like transporter family
MFFGAFPN_00575 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MFFGAFPN_00576 4.04e-149 ydfE - - S - - - Flavin reductase like domain
MFFGAFPN_00577 5.24e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MFFGAFPN_00578 1.31e-102 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MFFGAFPN_00580 7.24e-247 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFFGAFPN_00581 3.82e-141 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFFGAFPN_00582 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
MFFGAFPN_00583 7.67e-223 - - - S - - - Alpha/beta hydrolase family
MFFGAFPN_00584 7.6e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MFFGAFPN_00585 2.13e-189 - - - K - - - Bacterial transcription activator, effector binding domain
MFFGAFPN_00586 6.35e-200 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MFFGAFPN_00587 3.86e-142 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
MFFGAFPN_00588 3.18e-237 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MFFGAFPN_00589 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
MFFGAFPN_00590 1.32e-74 ydfQ - - CO - - - Thioredoxin
MFFGAFPN_00591 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
MFFGAFPN_00592 5.33e-39 - - - - - - - -
MFFGAFPN_00594 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
MFFGAFPN_00595 1.81e-159 ydfS - - S - - - Protein of unknown function (DUF421)
MFFGAFPN_00596 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MFFGAFPN_00597 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
MFFGAFPN_00598 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
MFFGAFPN_00599 2.85e-126 ydgC - - K - - - Bacterial regulatory proteins, tetR family
MFFGAFPN_00600 5.76e-70 - - - S - - - DoxX-like family
MFFGAFPN_00601 1.97e-111 yycN - - K - - - Acetyltransferase
MFFGAFPN_00602 2.79e-40 - - - FG ko:K02503 - ko00000,ko04147 HIT domain
MFFGAFPN_00603 3.62e-168 idhA 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
MFFGAFPN_00604 1.16e-151 - - - K - - - helix_turn _helix lactose operon repressor
MFFGAFPN_00605 6.82e-240 xylT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MFFGAFPN_00606 9.13e-132 - - - G - - - Xylose isomerase-like TIM barrel
MFFGAFPN_00607 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
MFFGAFPN_00608 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
MFFGAFPN_00609 5.94e-118 - - - S - - - DinB family
MFFGAFPN_00610 2.06e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MFFGAFPN_00611 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
MFFGAFPN_00612 6.42e-147 ydgI - - C - - - nitroreductase
MFFGAFPN_00613 3.29e-90 - - - K - - - Winged helix DNA-binding domain
MFFGAFPN_00614 8.12e-265 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
MFFGAFPN_00615 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
MFFGAFPN_00616 7.15e-156 ydhC - - K - - - FCD
MFFGAFPN_00617 4.24e-308 ydhD - - M - - - Glycosyl hydrolase
MFFGAFPN_00618 6.49e-288 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MFFGAFPN_00619 1.05e-163 - - - - - - - -
MFFGAFPN_00620 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
MFFGAFPN_00621 3.33e-89 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
MFFGAFPN_00623 3.25e-109 - - - K - - - Acetyltransferase (GNAT) domain
MFFGAFPN_00624 1.1e-230 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MFFGAFPN_00625 8.08e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
MFFGAFPN_00626 1.8e-254 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
MFFGAFPN_00627 2.29e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MFFGAFPN_00628 4.13e-68 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MFFGAFPN_00629 2.27e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFFGAFPN_00630 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MFFGAFPN_00631 7.75e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
MFFGAFPN_00632 8.91e-217 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
MFFGAFPN_00633 6.2e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MFFGAFPN_00634 2.64e-268 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
MFFGAFPN_00635 4.02e-201 ydhU - - P ko:K07217 - ko00000 Catalase
MFFGAFPN_00638 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
MFFGAFPN_00641 1.9e-231 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MFFGAFPN_00642 7.42e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
MFFGAFPN_00643 1.76e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
MFFGAFPN_00644 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MFFGAFPN_00645 5.46e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MFFGAFPN_00646 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
MFFGAFPN_00647 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MFFGAFPN_00648 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MFFGAFPN_00649 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MFFGAFPN_00650 3.55e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MFFGAFPN_00651 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
MFFGAFPN_00652 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
MFFGAFPN_00653 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MFFGAFPN_00654 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MFFGAFPN_00655 2.57e-191 ydjC - - S - - - Abhydrolase domain containing 18
MFFGAFPN_00656 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
MFFGAFPN_00657 1.51e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
MFFGAFPN_00658 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
MFFGAFPN_00659 1.42e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
MFFGAFPN_00660 2.65e-146 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
MFFGAFPN_00661 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MFFGAFPN_00662 2.2e-174 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
MFFGAFPN_00663 3.61e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
MFFGAFPN_00664 3.77e-246 - - - S - - - Ion transport 2 domain protein
MFFGAFPN_00665 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MFFGAFPN_00666 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
MFFGAFPN_00667 1.79e-84 ydjM - - M - - - Lytic transglycolase
MFFGAFPN_00668 2.07e-210 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
MFFGAFPN_00670 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
MFFGAFPN_00671 2.95e-201 - - - I - - - Alpha/beta hydrolase family
MFFGAFPN_00672 3.78e-224 yeaA - - S - - - Protein of unknown function (DUF4003)
MFFGAFPN_00673 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
MFFGAFPN_00674 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
MFFGAFPN_00675 1.76e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MFFGAFPN_00676 1.54e-223 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
MFFGAFPN_00677 3.74e-284 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MFFGAFPN_00678 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
MFFGAFPN_00679 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MFFGAFPN_00680 1.96e-114 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MFFGAFPN_00681 2.32e-314 - - - S - - - Domain of unknown function (DUF4179)
MFFGAFPN_00682 1.98e-282 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MFFGAFPN_00683 5.85e-165 yebC - - M - - - Membrane
MFFGAFPN_00685 1.08e-119 yebE - - S - - - UPF0316 protein
MFFGAFPN_00686 3.13e-38 yebG - - S - - - NETI protein
MFFGAFPN_00687 3.78e-107 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MFFGAFPN_00688 9e-276 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MFFGAFPN_00689 2.81e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MFFGAFPN_00690 5.86e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MFFGAFPN_00691 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MFFGAFPN_00692 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MFFGAFPN_00693 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MFFGAFPN_00694 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MFFGAFPN_00695 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MFFGAFPN_00696 8.88e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MFFGAFPN_00697 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MFFGAFPN_00698 3.29e-297 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MFFGAFPN_00699 2.51e-94 - - - K - - - helix_turn_helix ASNC type
MFFGAFPN_00700 2.54e-286 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
MFFGAFPN_00701 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
MFFGAFPN_00702 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
MFFGAFPN_00703 9.58e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
MFFGAFPN_00704 7.62e-68 yerC - - S - - - protein conserved in bacteria
MFFGAFPN_00705 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
MFFGAFPN_00706 1.82e-160 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MFFGAFPN_00707 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MFFGAFPN_00708 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MFFGAFPN_00709 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
MFFGAFPN_00710 7.33e-252 yerI - - S - - - homoserine kinase type II (protein kinase fold)
MFFGAFPN_00711 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
MFFGAFPN_00712 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MFFGAFPN_00713 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MFFGAFPN_00714 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MFFGAFPN_00715 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MFFGAFPN_00716 1.26e-191 yerO - - K - - - Transcriptional regulator
MFFGAFPN_00717 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MFFGAFPN_00718 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MFFGAFPN_00719 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MFFGAFPN_00720 1.84e-61 - - - K - - - Putative DNA-binding domain
MFFGAFPN_00721 0.0 - - - L - - - AAA ATPase domain
MFFGAFPN_00722 5.71e-33 - - - L - - - UvrD/REP helicase N-terminal domain
MFFGAFPN_00723 9.07e-33 - - - - - - - -
MFFGAFPN_00726 1.17e-74 - - - S - - - Tetratricopeptide repeat
MFFGAFPN_00727 0.000149 - - - - - - - -
MFFGAFPN_00728 1.63e-52 - - - S - - - Immunity protein 22
MFFGAFPN_00729 1.29e-16 - - - S - - - Protein of unknown function, DUF600
MFFGAFPN_00730 7.88e-29 - - - S - - - Colicin immunity protein / pyocin immunity protein
MFFGAFPN_00731 1.42e-239 - - - S - - - Bacterial EndoU nuclease
MFFGAFPN_00733 1.4e-126 - - - L - - - endonuclease activity
MFFGAFPN_00734 1.1e-13 - - - S - - - Lysozyme inhibitor LprI
MFFGAFPN_00735 4.08e-270 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
MFFGAFPN_00737 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
MFFGAFPN_00739 3.46e-130 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
MFFGAFPN_00740 3.92e-104 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
MFFGAFPN_00741 1.01e-194 yesF - - GM - - - NAD(P)H-binding
MFFGAFPN_00742 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
MFFGAFPN_00743 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
MFFGAFPN_00744 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
MFFGAFPN_00745 2.7e-127 yesJ - - K - - - Acetyltransferase (GNAT) family
MFFGAFPN_00747 2.1e-131 yesL - - S - - - Protein of unknown function, DUF624
MFFGAFPN_00748 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFFGAFPN_00749 5.66e-257 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
MFFGAFPN_00750 4.82e-313 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MFFGAFPN_00751 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MFFGAFPN_00752 2.96e-209 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MFFGAFPN_00753 5.4e-252 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
MFFGAFPN_00754 0.0 yesS - - K - - - Transcriptional regulator
MFFGAFPN_00755 4.47e-165 - - - E - - - GDSL-like Lipase/Acylhydrolase
MFFGAFPN_00756 3.72e-165 yesU - - S - - - Domain of unknown function (DUF1961)
MFFGAFPN_00757 1.91e-143 - - - S - - - Protein of unknown function, DUF624
MFFGAFPN_00758 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
MFFGAFPN_00759 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
MFFGAFPN_00760 1.52e-158 - - - E - - - GDSL-like Lipase/Acylhydrolase
MFFGAFPN_00761 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
MFFGAFPN_00762 0.0 yetA - - - - - - -
MFFGAFPN_00763 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MFFGAFPN_00764 1.18e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
MFFGAFPN_00765 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MFFGAFPN_00766 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
MFFGAFPN_00767 3.66e-157 yetF - - S - - - membrane
MFFGAFPN_00768 4.5e-71 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
MFFGAFPN_00769 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFFGAFPN_00770 1.75e-44 - - - - - - - -
MFFGAFPN_00771 7.23e-184 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MFFGAFPN_00772 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
MFFGAFPN_00773 4.23e-134 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
MFFGAFPN_00774 2.1e-202 - - - EG - - - EamA-like transporter family
MFFGAFPN_00775 6.74e-117 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
MFFGAFPN_00776 1.12e-268 yetM - - CH - - - FAD binding domain
MFFGAFPN_00777 6.1e-255 yetN - - S - - - Protein of unknown function (DUF3900)
MFFGAFPN_00778 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
MFFGAFPN_00779 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
MFFGAFPN_00780 1.7e-187 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
MFFGAFPN_00781 4.79e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
MFFGAFPN_00782 1.62e-230 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
MFFGAFPN_00783 2.84e-285 yfnE - - S - - - Glycosyltransferase like family 2
MFFGAFPN_00784 3.19e-241 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
MFFGAFPN_00785 1.25e-267 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MFFGAFPN_00786 9.05e-169 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MFFGAFPN_00787 3.41e-312 yfnA - - E ko:K03294 - ko00000 amino acid
MFFGAFPN_00788 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MFFGAFPN_00789 5.14e-161 yfmS - - NT - - - chemotaxis protein
MFFGAFPN_00790 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MFFGAFPN_00791 1.79e-96 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
MFFGAFPN_00792 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
MFFGAFPN_00793 2.95e-264 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
MFFGAFPN_00794 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MFFGAFPN_00795 4.19e-263 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
MFFGAFPN_00796 1.17e-101 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
MFFGAFPN_00797 2e-240 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
MFFGAFPN_00798 3.46e-268 - - - G - - - Major Facilitator Superfamily
MFFGAFPN_00799 0.0 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
MFFGAFPN_00800 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MFFGAFPN_00801 2.1e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFFGAFPN_00802 4.72e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFFGAFPN_00803 1.94e-219 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MFFGAFPN_00804 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
MFFGAFPN_00805 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
MFFGAFPN_00806 2.45e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
MFFGAFPN_00807 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MFFGAFPN_00808 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MFFGAFPN_00809 1.88e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MFFGAFPN_00810 3.98e-230 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
MFFGAFPN_00811 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
MFFGAFPN_00812 4.01e-191 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MFFGAFPN_00813 9.28e-274 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MFFGAFPN_00814 2.54e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MFFGAFPN_00815 3.42e-157 yflK - - S - - - protein conserved in bacteria
MFFGAFPN_00816 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
MFFGAFPN_00817 6.9e-27 yflI - - - - - - -
MFFGAFPN_00818 2.1e-65 yflH - - S - - - Protein of unknown function (DUF3243)
MFFGAFPN_00819 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
MFFGAFPN_00820 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MFFGAFPN_00821 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
MFFGAFPN_00822 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
MFFGAFPN_00823 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
MFFGAFPN_00824 1.04e-247 yfkT - - E ko:K06309 - ko00000 Spore germination protein
MFFGAFPN_00826 7.62e-270 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
MFFGAFPN_00827 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
MFFGAFPN_00828 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MFFGAFPN_00829 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
MFFGAFPN_00830 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
MFFGAFPN_00831 6.16e-160 frp - - C - - - nitroreductase
MFFGAFPN_00832 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MFFGAFPN_00833 7.78e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
MFFGAFPN_00834 6.21e-266 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MFFGAFPN_00835 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
MFFGAFPN_00836 8.37e-108 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MFFGAFPN_00837 8.49e-66 yfkI - - S - - - gas vesicle protein
MFFGAFPN_00838 5.58e-183 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MFFGAFPN_00839 1.64e-12 - - - - - - - -
MFFGAFPN_00840 2.7e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MFFGAFPN_00841 5.44e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
MFFGAFPN_00842 5.24e-189 yfkD - - S - - - YfkD-like protein
MFFGAFPN_00843 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
MFFGAFPN_00844 1.76e-283 yfkA - - S - - - YfkB-like domain
MFFGAFPN_00845 3.26e-36 yfjT - - - - - - -
MFFGAFPN_00846 7.24e-198 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
MFFGAFPN_00847 6.85e-194 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MFFGAFPN_00848 4.51e-236 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
MFFGAFPN_00849 7.91e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MFFGAFPN_00850 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MFFGAFPN_00851 1.65e-241 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MFFGAFPN_00852 4.56e-37 yfjM - - S - - - Psort location Cytoplasmic, score
MFFGAFPN_00854 2.75e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MFFGAFPN_00855 1.86e-242 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MFFGAFPN_00856 4.89e-264 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MFFGAFPN_00857 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MFFGAFPN_00858 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
MFFGAFPN_00859 2.75e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
MFFGAFPN_00860 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
MFFGAFPN_00861 1.9e-109 - - - S - - - Family of unknown function (DUF5381)
MFFGAFPN_00862 3.83e-161 yfjC - - - - - - -
MFFGAFPN_00863 5.67e-240 yfjB - - - - - - -
MFFGAFPN_00864 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
MFFGAFPN_00865 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MFFGAFPN_00866 5.03e-180 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
MFFGAFPN_00867 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MFFGAFPN_00868 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
MFFGAFPN_00869 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
MFFGAFPN_00870 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MFFGAFPN_00871 3.34e-83 yfiD3 - - S - - - DoxX
MFFGAFPN_00872 5.98e-208 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
MFFGAFPN_00874 5.09e-274 baeS - - T - - - Histidine kinase
MFFGAFPN_00875 4.27e-146 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
MFFGAFPN_00876 8.83e-214 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFGAFPN_00877 2.53e-265 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MFFGAFPN_00878 8.09e-261 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
MFFGAFPN_00879 1.89e-128 padR - - K - - - transcriptional
MFFGAFPN_00880 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
MFFGAFPN_00881 5.17e-250 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MFFGAFPN_00882 9.81e-129 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
MFFGAFPN_00883 0.0 yfiU - - EGP - - - the major facilitator superfamily
MFFGAFPN_00884 2.11e-103 yfiV - - K - - - transcriptional
MFFGAFPN_00885 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MFFGAFPN_00886 1.56e-230 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MFFGAFPN_00887 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFFGAFPN_00888 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFFGAFPN_00889 7.61e-215 yfhB - - S - - - PhzF family
MFFGAFPN_00890 2.87e-138 yfhC - - C - - - nitroreductase
MFFGAFPN_00891 8.86e-35 yfhD - - S - - - YfhD-like protein
MFFGAFPN_00893 1.09e-219 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
MFFGAFPN_00894 1.55e-179 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
MFFGAFPN_00895 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
MFFGAFPN_00896 2.45e-268 yfhI - - EGP - - - -transporter
MFFGAFPN_00897 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
MFFGAFPN_00898 8.95e-60 yfhJ - - S - - - WVELL protein
MFFGAFPN_00899 1.91e-114 yfhK - - T - - - Bacterial SH3 domain homologues
MFFGAFPN_00900 5.4e-67 yfhL - - S - - - SdpI/YhfL protein family
MFFGAFPN_00901 1.13e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
MFFGAFPN_00902 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MFFGAFPN_00903 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MFFGAFPN_00904 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
MFFGAFPN_00905 5.31e-265 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
MFFGAFPN_00906 1.73e-48 yfhS - - - - - - -
MFFGAFPN_00907 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFFGAFPN_00908 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
MFFGAFPN_00909 2.01e-49 ygaB - - S - - - YgaB-like protein
MFFGAFPN_00910 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
MFFGAFPN_00911 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
MFFGAFPN_00912 1.87e-238 ygaE - - S - - - Membrane
MFFGAFPN_00913 3.26e-312 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
MFFGAFPN_00914 1.19e-112 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
MFFGAFPN_00915 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
MFFGAFPN_00916 5.46e-74 ygzB - - S - - - UPF0295 protein
MFFGAFPN_00917 2.36e-214 ygxA - - S - - - Nucleotidyltransferase-like
MFFGAFPN_00918 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
MFFGAFPN_00935 2.22e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
MFFGAFPN_00936 1.58e-36 - - - - - - - -
MFFGAFPN_00937 8.12e-172 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
MFFGAFPN_00938 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MFFGAFPN_00939 0.0 ygaK - - C - - - Berberine and berberine like
MFFGAFPN_00941 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MFFGAFPN_00942 7.1e-176 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MFFGAFPN_00943 1.15e-215 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
MFFGAFPN_00944 5.86e-190 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MFFGAFPN_00945 9.35e-276 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
MFFGAFPN_00947 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MFFGAFPN_00948 2.79e-102 ygaO - - - - - - -
MFFGAFPN_00949 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
MFFGAFPN_00951 1.92e-147 yhzB - - S - - - B3/4 domain
MFFGAFPN_00952 1.7e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MFFGAFPN_00953 1.32e-223 yhbB - - S - - - Putative amidase domain
MFFGAFPN_00954 6.53e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MFFGAFPN_00955 3.4e-143 yhbD - - K - - - Protein of unknown function (DUF4004)
MFFGAFPN_00956 6.56e-96 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
MFFGAFPN_00957 4.08e-110 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
MFFGAFPN_00958 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
MFFGAFPN_00959 4.92e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
MFFGAFPN_00960 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
MFFGAFPN_00961 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
MFFGAFPN_00962 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
MFFGAFPN_00963 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
MFFGAFPN_00964 3.95e-59 yhcC - - - - - - -
MFFGAFPN_00965 1.03e-69 - - - - - - - -
MFFGAFPN_00966 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
MFFGAFPN_00967 3.24e-156 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFGAFPN_00968 7.55e-212 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFGAFPN_00969 3.45e-212 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MFFGAFPN_00970 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
MFFGAFPN_00971 1.34e-195 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MFFGAFPN_00972 7.08e-251 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
MFFGAFPN_00973 1.51e-300 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MFFGAFPN_00974 1.13e-70 yhcM - - - - - - -
MFFGAFPN_00975 1.74e-107 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MFFGAFPN_00976 3.64e-223 yhcP - - - - - - -
MFFGAFPN_00977 1.68e-146 yhcQ - - M - - - Spore coat protein
MFFGAFPN_00978 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MFFGAFPN_00979 7.24e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
MFFGAFPN_00980 4.78e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MFFGAFPN_00981 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
MFFGAFPN_00982 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
MFFGAFPN_00983 6.14e-155 yhcW - - S ko:K07025 - ko00000 hydrolase
MFFGAFPN_00984 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MFFGAFPN_00985 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MFFGAFPN_00986 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MFFGAFPN_00987 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MFFGAFPN_00988 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MFFGAFPN_00989 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MFFGAFPN_00990 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
MFFGAFPN_00991 3.11e-271 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
MFFGAFPN_00992 1.28e-142 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFFGAFPN_00993 6.64e-116 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
MFFGAFPN_00994 1.65e-51 yhdB - - S - - - YhdB-like protein
MFFGAFPN_00995 8.44e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
MFFGAFPN_00996 7.61e-272 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MFFGAFPN_00997 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
MFFGAFPN_00998 1.44e-304 ygxB - - M - - - Conserved TM helix
MFFGAFPN_00999 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
MFFGAFPN_01000 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
MFFGAFPN_01001 1.45e-203 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MFFGAFPN_01002 2.85e-209 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
MFFGAFPN_01003 9.13e-262 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MFFGAFPN_01004 1.41e-208 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFFGAFPN_01005 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
MFFGAFPN_01006 5e-309 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MFFGAFPN_01007 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MFFGAFPN_01008 1.22e-97 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFFGAFPN_01009 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
MFFGAFPN_01010 6.13e-258 yhdL - - S - - - Sigma factor regulator N-terminal
MFFGAFPN_01011 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MFFGAFPN_01012 6.74e-244 yhdN - - C - - - Aldo keto reductase
MFFGAFPN_01013 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MFFGAFPN_01014 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MFFGAFPN_01015 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
MFFGAFPN_01016 1.4e-281 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MFFGAFPN_01017 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
MFFGAFPN_01018 2.69e-70 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MFFGAFPN_01019 1.43e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MFFGAFPN_01020 9.03e-173 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MFFGAFPN_01021 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
MFFGAFPN_01022 9.73e-239 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
MFFGAFPN_01023 8.39e-180 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MFFGAFPN_01024 2.23e-197 nodB1 - - G - - - deacetylase
MFFGAFPN_01025 9.07e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MFFGAFPN_01026 7.28e-303 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
MFFGAFPN_01027 1.29e-107 nhaX - - T - - - Belongs to the universal stress protein A family
MFFGAFPN_01028 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MFFGAFPN_01029 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MFFGAFPN_01030 3.31e-143 yheG - - GM - - - NAD(P)H-binding
MFFGAFPN_01031 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
MFFGAFPN_01032 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
MFFGAFPN_01033 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
MFFGAFPN_01034 9.67e-276 yheC - - HJ - - - YheC/D like ATP-grasp
MFFGAFPN_01035 1.69e-258 yheB - - S - - - Belongs to the UPF0754 family
MFFGAFPN_01036 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
MFFGAFPN_01037 2.15e-260 yhaZ - - L - - - DNA alkylation repair enzyme
MFFGAFPN_01038 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
MFFGAFPN_01039 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
MFFGAFPN_01040 2.63e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
MFFGAFPN_01041 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
MFFGAFPN_01043 7.3e-169 yhaR - - I - - - enoyl-CoA hydratase
MFFGAFPN_01044 9.36e-36 - - - S - - - YhzD-like protein
MFFGAFPN_01045 1.86e-213 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFGAFPN_01046 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
MFFGAFPN_01047 3.16e-299 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
MFFGAFPN_01048 0.0 yhaN - - L - - - AAA domain
MFFGAFPN_01049 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
MFFGAFPN_01050 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
MFFGAFPN_01051 1.81e-178 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MFFGAFPN_01052 1.4e-116 yhaK - - S - - - Putative zincin peptidase
MFFGAFPN_01053 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
MFFGAFPN_01054 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
MFFGAFPN_01055 1.74e-54 yhaH - - S - - - YtxH-like protein
MFFGAFPN_01056 9.66e-30 - - - - - - - -
MFFGAFPN_01057 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
MFFGAFPN_01058 8.76e-261 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MFFGAFPN_01059 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MFFGAFPN_01060 3.15e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
MFFGAFPN_01061 1.27e-271 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MFFGAFPN_01062 5.83e-161 ecsC - - S - - - EcsC protein family
MFFGAFPN_01063 7.63e-292 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MFFGAFPN_01064 5.44e-312 yhfA - - C - - - membrane
MFFGAFPN_01065 2.87e-44 - - - C - - - Rubrerythrin
MFFGAFPN_01066 6.25e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
MFFGAFPN_01067 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MFFGAFPN_01068 4.14e-256 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MFFGAFPN_01069 3.99e-230 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
MFFGAFPN_01070 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MFFGAFPN_01071 5.79e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
MFFGAFPN_01072 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
MFFGAFPN_01073 4.87e-234 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MFFGAFPN_01074 9.33e-178 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
MFFGAFPN_01075 7.68e-253 yhfE - - G - - - peptidase M42
MFFGAFPN_01076 2.54e-92 - - - S - - - ASCH
MFFGAFPN_01077 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MFFGAFPN_01078 1.2e-182 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MFFGAFPN_01079 1.66e-244 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MFFGAFPN_01080 7.43e-144 yhfK - - GM - - - NmrA-like family
MFFGAFPN_01081 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
MFFGAFPN_01082 2.78e-85 yhfM - - - - - - -
MFFGAFPN_01083 9.64e-308 yhfN - - O - - - Peptidase M48
MFFGAFPN_01084 1.7e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MFFGAFPN_01085 2.96e-100 - - - K - - - acetyltransferase
MFFGAFPN_01086 8.03e-231 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
MFFGAFPN_01087 2.77e-223 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MFFGAFPN_01088 3.93e-140 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
MFFGAFPN_01089 2.46e-249 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MFFGAFPN_01090 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
MFFGAFPN_01091 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
MFFGAFPN_01092 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
MFFGAFPN_01093 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
MFFGAFPN_01094 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFFGAFPN_01095 9.84e-45 yhzC - - S - - - IDEAL
MFFGAFPN_01096 6.29e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
MFFGAFPN_01097 4.74e-212 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MFFGAFPN_01098 1.68e-55 yhjA - - S - - - Excalibur calcium-binding domain
MFFGAFPN_01099 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MFFGAFPN_01100 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
MFFGAFPN_01101 4.13e-78 yhjD - - - - - - -
MFFGAFPN_01102 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
MFFGAFPN_01103 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MFFGAFPN_01104 0.0 yhjG - - CH - - - FAD binding domain
MFFGAFPN_01105 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
MFFGAFPN_01106 8.57e-271 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
MFFGAFPN_01107 6.61e-256 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
MFFGAFPN_01108 3.07e-204 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
MFFGAFPN_01109 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
MFFGAFPN_01110 2.52e-238 yhjM - - K - - - Transcriptional regulator
MFFGAFPN_01111 2.5e-259 yhjN - - S ko:K07120 - ko00000 membrane
MFFGAFPN_01112 1.04e-271 - - - EGP - - - Transmembrane secretion effector
MFFGAFPN_01113 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
MFFGAFPN_01114 1.19e-66 yhjQ - - C - - - COG1145 Ferredoxin
MFFGAFPN_01115 9.3e-102 yhjR - - S - - - Rubrerythrin
MFFGAFPN_01116 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
MFFGAFPN_01117 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MFFGAFPN_01118 6.64e-279 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MFFGAFPN_01119 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
MFFGAFPN_01120 6.4e-65 yisB - - V - - - COG1403 Restriction endonuclease
MFFGAFPN_01121 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
MFFGAFPN_01122 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
MFFGAFPN_01123 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
MFFGAFPN_01124 2.88e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
MFFGAFPN_01125 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
MFFGAFPN_01126 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
MFFGAFPN_01127 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
MFFGAFPN_01128 4.62e-223 cotH - - M ko:K06330 - ko00000 Spore Coat
MFFGAFPN_01129 2.66e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MFFGAFPN_01130 1.02e-74 yisL - - S - - - UPF0344 protein
MFFGAFPN_01131 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MFFGAFPN_01132 3.68e-132 yisN - - S - - - Protein of unknown function (DUF2777)
MFFGAFPN_01133 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MFFGAFPN_01134 1.07e-114 yizA - - S - - - Damage-inducible protein DinB
MFFGAFPN_01135 1.54e-189 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
MFFGAFPN_01136 1.01e-310 yisQ - - V - - - Mate efflux family protein
MFFGAFPN_01137 1.16e-206 yisR - - K - - - Transcriptional regulator
MFFGAFPN_01138 1.06e-234 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MFFGAFPN_01139 3.12e-250 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
MFFGAFPN_01140 9.94e-120 yisT - - S - - - DinB family
MFFGAFPN_01141 1.77e-88 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
MFFGAFPN_01142 9.36e-27 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
MFFGAFPN_01143 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MFFGAFPN_01144 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
MFFGAFPN_01145 6.44e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MFFGAFPN_01146 4.75e-144 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
MFFGAFPN_01147 1.87e-293 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
MFFGAFPN_01148 3.87e-184 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
MFFGAFPN_01149 1.34e-162 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
MFFGAFPN_01150 4.31e-180 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
MFFGAFPN_01151 6.77e-145 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MFFGAFPN_01152 3.97e-279 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
MFFGAFPN_01153 1.67e-290 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MFFGAFPN_01154 5.09e-203 yitH - - K - - - Acetyltransferase (GNAT) domain
MFFGAFPN_01155 1.93e-105 - - - S - - - Acetyltransferase (GNAT) domain
MFFGAFPN_01156 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MFFGAFPN_01157 1.06e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
MFFGAFPN_01158 1.94e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
MFFGAFPN_01159 4.16e-122 - - - - - - - -
MFFGAFPN_01160 1.42e-218 - - - - - - - -
MFFGAFPN_01161 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
MFFGAFPN_01162 1.2e-76 - - - K - - - Transcriptional regulator PadR-like family
MFFGAFPN_01163 5.24e-121 - - - - - - - -
MFFGAFPN_01164 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
MFFGAFPN_01165 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
MFFGAFPN_01166 3.56e-199 yitS - - S - - - protein conserved in bacteria
MFFGAFPN_01167 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MFFGAFPN_01168 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
MFFGAFPN_01169 4.11e-25 - - - S - - - Protein of unknown function (DUF3813)
MFFGAFPN_01170 1.92e-08 - - - - - - - -
MFFGAFPN_01171 8.78e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MFFGAFPN_01172 5.05e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MFFGAFPN_01173 4.63e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
MFFGAFPN_01174 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
MFFGAFPN_01175 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
MFFGAFPN_01176 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
MFFGAFPN_01177 3.52e-253 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MFFGAFPN_01178 1.43e-292 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MFFGAFPN_01179 1.81e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
MFFGAFPN_01180 1.14e-276 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
MFFGAFPN_01181 9.47e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MFFGAFPN_01182 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
MFFGAFPN_01183 1.74e-224 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MFFGAFPN_01184 2.51e-39 yjzC - - S - - - YjzC-like protein
MFFGAFPN_01185 1.53e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
MFFGAFPN_01186 4.88e-182 yjaU - - I - - - carboxylic ester hydrolase activity
MFFGAFPN_01187 4.28e-131 yjaV - - - - - - -
MFFGAFPN_01188 2.14e-233 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
MFFGAFPN_01189 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
MFFGAFPN_01190 2.67e-38 yjzB - - - - - - -
MFFGAFPN_01191 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MFFGAFPN_01192 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MFFGAFPN_01193 3.17e-191 yjaZ - - O - - - Zn-dependent protease
MFFGAFPN_01194 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MFFGAFPN_01195 3.43e-236 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MFFGAFPN_01196 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
MFFGAFPN_01197 6.73e-216 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFFGAFPN_01198 4.88e-207 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFFGAFPN_01199 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
MFFGAFPN_01200 2.06e-233 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
MFFGAFPN_01201 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MFFGAFPN_01202 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFFGAFPN_01203 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFFGAFPN_01204 1.12e-248 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MFFGAFPN_01205 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MFFGAFPN_01206 2.3e-247 yjbB - - EGP - - - Major Facilitator Superfamily
MFFGAFPN_01207 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFFGAFPN_01208 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MFFGAFPN_01209 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
MFFGAFPN_01210 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MFFGAFPN_01211 1.57e-275 coiA - - S ko:K06198 - ko00000 Competence protein
MFFGAFPN_01212 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MFFGAFPN_01213 2.68e-28 - - - - - - - -
MFFGAFPN_01214 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
MFFGAFPN_01215 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
MFFGAFPN_01216 8.41e-128 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MFFGAFPN_01217 4.94e-128 yjbK - - S - - - protein conserved in bacteria
MFFGAFPN_01218 3.1e-80 yjbL - - S - - - Belongs to the UPF0738 family
MFFGAFPN_01219 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
MFFGAFPN_01220 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MFFGAFPN_01221 1.49e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MFFGAFPN_01222 3.3e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MFFGAFPN_01223 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MFFGAFPN_01224 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MFFGAFPN_01225 2.32e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
MFFGAFPN_01226 5.4e-276 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
MFFGAFPN_01227 2.18e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
MFFGAFPN_01228 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MFFGAFPN_01229 6.18e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MFFGAFPN_01230 6.89e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MFFGAFPN_01231 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
MFFGAFPN_01232 3.11e-98 yjbX - - S - - - Spore coat protein
MFFGAFPN_01233 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
MFFGAFPN_01234 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
MFFGAFPN_01235 3.55e-110 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
MFFGAFPN_01236 2.34e-51 cotW - - - ko:K06341 - ko00000 -
MFFGAFPN_01237 1.44e-72 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
MFFGAFPN_01238 5.03e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
MFFGAFPN_01241 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
MFFGAFPN_01242 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MFFGAFPN_01243 6.31e-51 - - - - - - - -
MFFGAFPN_01244 2.22e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFFGAFPN_01245 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
MFFGAFPN_01246 2.6e-175 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
MFFGAFPN_01247 8.05e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MFFGAFPN_01248 1.84e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MFFGAFPN_01249 7.14e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
MFFGAFPN_01250 2.47e-272 yjcL - - S - - - Protein of unknown function (DUF819)
MFFGAFPN_01252 3.46e-23 - - - - - - - -
MFFGAFPN_01253 3.27e-41 - - - - - - - -
MFFGAFPN_01254 9.03e-305 - - - M - - - nucleic acid phosphodiester bond hydrolysis
MFFGAFPN_01258 1.34e-223 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MFFGAFPN_01259 1.27e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
MFFGAFPN_01260 2.31e-179 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MFFGAFPN_01261 0.000388 - - - - - - - -
MFFGAFPN_01262 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
MFFGAFPN_01263 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MFFGAFPN_01264 1.03e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MFFGAFPN_01265 3.93e-77 yjdF3 - - S - - - Protein of unknown function (DUF2992)
MFFGAFPN_01266 1.26e-117 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MFFGAFPN_01268 9.69e-104 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MFFGAFPN_01269 3.55e-39 - - - S - - - Domain of unknown function (DUF4177)
MFFGAFPN_01270 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
MFFGAFPN_01271 5.31e-224 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MFFGAFPN_01273 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
MFFGAFPN_01274 3.54e-105 - - - S - - - Protein of unknown function (DUF2690)
MFFGAFPN_01275 1.13e-29 yjfB - - S - - - Putative motility protein
MFFGAFPN_01276 7.02e-214 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
MFFGAFPN_01277 5.62e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
MFFGAFPN_01278 4.96e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
MFFGAFPN_01279 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
MFFGAFPN_01280 2.27e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
MFFGAFPN_01282 3.7e-147 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MFFGAFPN_01284 1.25e-281 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MFFGAFPN_01285 6.88e-277 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MFFGAFPN_01286 1.11e-41 - - - - - - - -
MFFGAFPN_01287 1.23e-188 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
MFFGAFPN_01288 1.82e-155 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
MFFGAFPN_01289 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MFFGAFPN_01290 3.12e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
MFFGAFPN_01291 2.36e-116 yjlB - - S - - - Cupin domain
MFFGAFPN_01292 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
MFFGAFPN_01293 3.56e-279 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MFFGAFPN_01294 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
MFFGAFPN_01295 1.51e-314 - - - G ko:K03292 - ko00000 symporter YjmB
MFFGAFPN_01296 4.2e-241 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
MFFGAFPN_01297 7.59e-245 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
MFFGAFPN_01298 4.58e-272 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
MFFGAFPN_01299 2.23e-195 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MFFGAFPN_01300 3.23e-288 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
MFFGAFPN_01301 9.87e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
MFFGAFPN_01302 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
MFFGAFPN_01303 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
MFFGAFPN_01304 2.64e-166 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
MFFGAFPN_01305 2.71e-103 yjoA - - S - - - DinB family
MFFGAFPN_01306 2.89e-312 VCP - - O - - - AAA domain (dynein-related subfamily)
MFFGAFPN_01307 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MFFGAFPN_01309 4.23e-54 - - - S - - - YCII-related domain
MFFGAFPN_01310 4.2e-215 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
MFFGAFPN_01311 7.52e-78 yjqA - - S - - - Bacterial PH domain
MFFGAFPN_01312 2.44e-142 yjqB - - S - - - Pfam:DUF867
MFFGAFPN_01313 1.85e-203 yjqC - - P ko:K07217 - ko00000 Catalase
MFFGAFPN_01314 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
MFFGAFPN_01315 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
MFFGAFPN_01317 3.73e-203 xkdB - - K - - - sequence-specific DNA binding
MFFGAFPN_01318 7.48e-153 xkdC - - L - - - Bacterial dnaA protein
MFFGAFPN_01322 5.95e-112 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MFFGAFPN_01323 1.18e-179 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
MFFGAFPN_01324 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
MFFGAFPN_01325 0.0 yqbA - - S - - - portal protein
MFFGAFPN_01326 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
MFFGAFPN_01327 3.91e-217 xkdG - - S - - - Phage capsid family
MFFGAFPN_01328 1.63e-82 yqbG - - S - - - Protein of unknown function (DUF3199)
MFFGAFPN_01329 1.44e-83 yqbH - - S - - - Domain of unknown function (DUF3599)
MFFGAFPN_01330 2.78e-113 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
MFFGAFPN_01331 4.77e-100 xkdJ - - - - - - -
MFFGAFPN_01332 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
MFFGAFPN_01333 6.01e-99 xkdM - - S - - - Phage tail tube protein
MFFGAFPN_01334 3.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
MFFGAFPN_01335 0.0 xkdO - - L - - - Transglycosylase SLT domain
MFFGAFPN_01336 2.1e-152 xkdP - - S - - - Lysin motif
MFFGAFPN_01337 5.22e-229 xkdQ - - G - - - NLP P60 protein
MFFGAFPN_01338 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
MFFGAFPN_01339 6.6e-91 xkdS - - S - - - Protein of unknown function (DUF2634)
MFFGAFPN_01340 2.17e-244 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MFFGAFPN_01341 3.92e-135 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
MFFGAFPN_01342 4.43e-56 - - - - - - - -
MFFGAFPN_01343 4.08e-221 - - - - - - - -
MFFGAFPN_01344 1.5e-58 xkdW - - S - - - XkdW protein
MFFGAFPN_01345 1.82e-30 xkdX - - - - - - -
MFFGAFPN_01346 6.89e-195 xepA - - - - - - -
MFFGAFPN_01347 7.71e-52 xhlA - - S - - - Haemolysin XhlA
MFFGAFPN_01348 1.11e-50 xhlB - - S - - - SPP1 phage holin
MFFGAFPN_01349 1.85e-208 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
MFFGAFPN_01351 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
MFFGAFPN_01352 1.97e-174 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
MFFGAFPN_01353 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
MFFGAFPN_01354 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
MFFGAFPN_01355 8.98e-310 steT - - E ko:K03294 - ko00000 amino acid
MFFGAFPN_01356 8.07e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MFFGAFPN_01357 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MFFGAFPN_01358 2.21e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MFFGAFPN_01360 6.72e-288 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFFGAFPN_01361 1.16e-178 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
MFFGAFPN_01362 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
MFFGAFPN_01363 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFFGAFPN_01364 3.02e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFFGAFPN_01365 1.64e-237 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MFFGAFPN_01366 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MFFGAFPN_01368 6.49e-223 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
MFFGAFPN_01369 1.89e-254 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
MFFGAFPN_01370 1.73e-217 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MFFGAFPN_01371 1.77e-238 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MFFGAFPN_01372 9.83e-262 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
MFFGAFPN_01373 2.53e-205 ykgA - - E - - - Amidinotransferase
MFFGAFPN_01374 3.82e-120 ykhA - - I - - - Acyl-CoA hydrolase
MFFGAFPN_01375 7.6e-289 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MFFGAFPN_01376 5.85e-13 - - - - - - - -
MFFGAFPN_01377 3.95e-167 ykjA - - S - - - Protein of unknown function (DUF421)
MFFGAFPN_01378 6.17e-126 ykkA - - S - - - Protein of unknown function (DUF664)
MFFGAFPN_01379 3.59e-128 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MFFGAFPN_01380 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
MFFGAFPN_01381 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
MFFGAFPN_01382 4.77e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MFFGAFPN_01383 7.43e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MFFGAFPN_01384 1.87e-288 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MFFGAFPN_01385 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
MFFGAFPN_01386 5.78e-97 ohrR - - K - - - COG1846 Transcriptional regulators
MFFGAFPN_01387 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
MFFGAFPN_01388 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
MFFGAFPN_01389 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MFFGAFPN_01390 1.49e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MFFGAFPN_01391 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MFFGAFPN_01392 3.12e-174 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MFFGAFPN_01393 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MFFGAFPN_01394 6.62e-126 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MFFGAFPN_01395 9.94e-142 ykoF - - S - - - YKOF-related Family
MFFGAFPN_01396 3.03e-159 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFFGAFPN_01397 2.46e-306 ykoH - - T - - - Histidine kinase
MFFGAFPN_01398 2.26e-144 ykoI - - S - - - Peptidase propeptide and YPEB domain
MFFGAFPN_01399 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
MFFGAFPN_01400 1.45e-08 - - - - - - - -
MFFGAFPN_01402 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
MFFGAFPN_01403 1.49e-70 tnrA - - K - - - transcriptional
MFFGAFPN_01404 1.63e-25 - - - - - - - -
MFFGAFPN_01405 3.04e-36 ykoL - - - - - - -
MFFGAFPN_01406 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
MFFGAFPN_01407 1.33e-278 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
MFFGAFPN_01408 1.44e-128 ykoP - - G - - - polysaccharide deacetylase
MFFGAFPN_01409 4.35e-198 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
MFFGAFPN_01410 0.0 ykoS - - - - - - -
MFFGAFPN_01411 5.72e-239 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
MFFGAFPN_01412 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
MFFGAFPN_01413 7.55e-206 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MFFGAFPN_01414 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
MFFGAFPN_01415 1.71e-143 ykoX - - S - - - membrane-associated protein
MFFGAFPN_01416 4.63e-227 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MFFGAFPN_01417 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFFGAFPN_01418 1.63e-212 rsgI - - S - - - Anti-sigma factor N-terminus
MFFGAFPN_01419 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
MFFGAFPN_01420 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
MFFGAFPN_01421 9.33e-198 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MFFGAFPN_01422 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
MFFGAFPN_01424 2.94e-27 ykzE - - - - - - -
MFFGAFPN_01425 6.46e-242 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
MFFGAFPN_01426 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFFGAFPN_01427 1.53e-112 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MFFGAFPN_01429 2.2e-251 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MFFGAFPN_01430 3.92e-290 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MFFGAFPN_01431 1.99e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MFFGAFPN_01432 2.67e-293 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MFFGAFPN_01433 2.29e-293 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MFFGAFPN_01434 4.17e-174 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MFFGAFPN_01435 1.06e-145 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MFFGAFPN_01436 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MFFGAFPN_01437 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
MFFGAFPN_01439 5.62e-93 eag - - - - - - -
MFFGAFPN_01440 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MFFGAFPN_01441 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
MFFGAFPN_01442 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
MFFGAFPN_01443 1.65e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
MFFGAFPN_01444 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
MFFGAFPN_01445 6.76e-227 ykvI - - S - - - membrane
MFFGAFPN_01446 2.61e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MFFGAFPN_01447 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
MFFGAFPN_01448 3.56e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MFFGAFPN_01449 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MFFGAFPN_01450 4.98e-78 - - - K - - - HxlR-like helix-turn-helix
MFFGAFPN_01451 2.11e-169 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MFFGAFPN_01452 2.69e-275 - - - M - - - Glycosyl transferases group 1
MFFGAFPN_01453 1.85e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
MFFGAFPN_01454 6.74e-106 - - - G - - - Glycosyl hydrolases family 18
MFFGAFPN_01455 3.9e-92 - - - G - - - Glycosyl hydrolases family 18
MFFGAFPN_01456 1.09e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
MFFGAFPN_01457 5.43e-35 ykvS - - S - - - protein conserved in bacteria
MFFGAFPN_01458 2.6e-39 - - - - - - - -
MFFGAFPN_01459 9.09e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
MFFGAFPN_01460 4.55e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MFFGAFPN_01461 2.76e-115 stoA - - CO - - - thiol-disulfide
MFFGAFPN_01462 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
MFFGAFPN_01463 3.99e-09 - - - - - - - -
MFFGAFPN_01464 1.25e-262 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
MFFGAFPN_01465 1.56e-228 ykvZ - - K - - - Transcriptional regulator
MFFGAFPN_01467 6.87e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
MFFGAFPN_01468 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MFFGAFPN_01469 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
MFFGAFPN_01470 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MFFGAFPN_01471 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
MFFGAFPN_01472 2.13e-257 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
MFFGAFPN_01473 2.93e-165 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFFGAFPN_01474 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MFFGAFPN_01475 5.48e-201 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MFFGAFPN_01476 1.54e-171 ykwD - - J - - - protein with SCP PR1 domains
MFFGAFPN_01477 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MFFGAFPN_01478 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFFGAFPN_01479 5.7e-281 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MFFGAFPN_01480 3e-22 - - - - - - - -
MFFGAFPN_01481 4.24e-217 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
MFFGAFPN_01482 3.71e-110 ykyB - - S - - - YkyB-like protein
MFFGAFPN_01483 6e-304 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MFFGAFPN_01484 5.84e-115 ykuD - - S - - - protein conserved in bacteria
MFFGAFPN_01485 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
MFFGAFPN_01486 1.5e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFFGAFPN_01487 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
MFFGAFPN_01488 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
MFFGAFPN_01489 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
MFFGAFPN_01490 7.83e-38 ykzF - - S - - - Antirepressor AbbA
MFFGAFPN_01491 5.15e-100 ykuL - - S - - - CBS domain
MFFGAFPN_01492 6.52e-216 ccpC - - K - - - Transcriptional regulator
MFFGAFPN_01493 6.35e-113 - - - C ko:K03839 - ko00000 Flavodoxin domain
MFFGAFPN_01494 3.51e-222 ykuO - - - - - - -
MFFGAFPN_01495 1.03e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
MFFGAFPN_01496 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MFFGAFPN_01497 1.33e-274 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MFFGAFPN_01498 4.9e-49 ykuS - - S - - - Belongs to the UPF0180 family
MFFGAFPN_01499 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
MFFGAFPN_01500 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
MFFGAFPN_01501 1.47e-104 ykuV - - CO - - - thiol-disulfide
MFFGAFPN_01502 4.71e-122 rok - - K - - - Repressor of ComK
MFFGAFPN_01503 5.72e-199 yknT - - - ko:K06437 - ko00000 -
MFFGAFPN_01504 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MFFGAFPN_01505 7.59e-245 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MFFGAFPN_01506 4.29e-313 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
MFFGAFPN_01507 4.89e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
MFFGAFPN_01508 3.83e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
MFFGAFPN_01509 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MFFGAFPN_01510 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MFFGAFPN_01511 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MFFGAFPN_01512 5.34e-150 yknW - - S - - - Yip1 domain
MFFGAFPN_01513 2.34e-233 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MFFGAFPN_01514 1.44e-158 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFGAFPN_01515 1.92e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
MFFGAFPN_01516 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
MFFGAFPN_01517 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
MFFGAFPN_01518 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MFFGAFPN_01519 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MFFGAFPN_01520 5.43e-52 ykoA - - - - - - -
MFFGAFPN_01521 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MFFGAFPN_01522 2.86e-215 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MFFGAFPN_01523 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
MFFGAFPN_01524 1.09e-18 - - - S - - - Uncharacterized protein YkpC
MFFGAFPN_01525 3.57e-233 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
MFFGAFPN_01526 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
MFFGAFPN_01527 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MFFGAFPN_01528 3.42e-198 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
MFFGAFPN_01529 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
MFFGAFPN_01530 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MFFGAFPN_01531 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MFFGAFPN_01532 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
MFFGAFPN_01533 4.79e-186 ykrA - - S - - - hydrolases of the HAD superfamily
MFFGAFPN_01534 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MFFGAFPN_01535 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MFFGAFPN_01536 2.59e-139 ykyA - - L - - - Putative cell-wall binding lipoprotein
MFFGAFPN_01537 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MFFGAFPN_01538 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MFFGAFPN_01539 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MFFGAFPN_01540 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MFFGAFPN_01541 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
MFFGAFPN_01542 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
MFFGAFPN_01543 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
MFFGAFPN_01544 5.28e-152 yktB - - S - - - Belongs to the UPF0637 family
MFFGAFPN_01545 4.48e-35 ykzI - - - - - - -
MFFGAFPN_01546 9.48e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
MFFGAFPN_01547 2.45e-99 ykzC - - S - - - Acetyltransferase (GNAT) family
MFFGAFPN_01548 4.98e-221 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MFFGAFPN_01549 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
MFFGAFPN_01550 0.0 ylaA - - - - - - -
MFFGAFPN_01551 1.44e-56 ylaB - - - - - - -
MFFGAFPN_01552 1.45e-114 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MFFGAFPN_01554 1.74e-57 ylaE - - - - - - -
MFFGAFPN_01555 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
MFFGAFPN_01556 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MFFGAFPN_01557 4.4e-63 ylaH - - S - - - YlaH-like protein
MFFGAFPN_01558 8.92e-44 ylaI - - S - - - protein conserved in bacteria
MFFGAFPN_01559 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MFFGAFPN_01560 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
MFFGAFPN_01561 1.09e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MFFGAFPN_01562 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
MFFGAFPN_01563 5.71e-58 ylaN - - S - - - Belongs to the UPF0358 family
MFFGAFPN_01564 2.87e-270 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MFFGAFPN_01565 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MFFGAFPN_01566 2e-212 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MFFGAFPN_01567 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MFFGAFPN_01568 6.83e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MFFGAFPN_01569 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MFFGAFPN_01570 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MFFGAFPN_01571 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MFFGAFPN_01572 2.98e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
MFFGAFPN_01573 1.61e-81 ylbA - - S - - - YugN-like family
MFFGAFPN_01574 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
MFFGAFPN_01575 8.87e-256 ylbC - - S - - - protein with SCP PR1 domains
MFFGAFPN_01576 3.24e-89 ylbD - - S - - - Putative coat protein
MFFGAFPN_01577 1.73e-48 ylbE - - S - - - YlbE-like protein
MFFGAFPN_01578 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
MFFGAFPN_01579 5.1e-51 ylbG - - S - - - UPF0298 protein
MFFGAFPN_01580 2.03e-124 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
MFFGAFPN_01581 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MFFGAFPN_01582 5.5e-282 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
MFFGAFPN_01583 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
MFFGAFPN_01584 1.58e-238 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MFFGAFPN_01585 5.94e-301 ylbM - - S - - - Belongs to the UPF0348 family
MFFGAFPN_01587 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
MFFGAFPN_01588 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MFFGAFPN_01589 4.72e-107 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MFFGAFPN_01590 1.55e-114 ylbP - - K - - - n-acetyltransferase
MFFGAFPN_01591 1.66e-216 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MFFGAFPN_01592 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MFFGAFPN_01593 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MFFGAFPN_01594 4.76e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MFFGAFPN_01595 3.42e-68 ftsL - - D - - - Essential cell division protein
MFFGAFPN_01596 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MFFGAFPN_01597 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
MFFGAFPN_01598 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MFFGAFPN_01599 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MFFGAFPN_01600 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MFFGAFPN_01601 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MFFGAFPN_01602 3.15e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MFFGAFPN_01603 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
MFFGAFPN_01604 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MFFGAFPN_01605 2.23e-142 ylxW - - S - - - protein conserved in bacteria
MFFGAFPN_01606 1.06e-132 ylxX - - S - - - protein conserved in bacteria
MFFGAFPN_01607 5.37e-76 sbp - - S - - - small basic protein
MFFGAFPN_01608 3.44e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MFFGAFPN_01609 1.61e-219 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MFFGAFPN_01610 0.0 - - - Q ko:K15662 ko01054,map01054 ko00000,ko00001,ko01008 Non-ribosomal peptide synthetase modules and related proteins
MFFGAFPN_01611 0.0 - - - Q - - - Non-ribosomal peptide synthetase modules and related proteins
MFFGAFPN_01612 1.36e-53 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MFFGAFPN_01613 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
MFFGAFPN_01614 1.06e-220 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MFFGAFPN_01615 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFFGAFPN_01616 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFFGAFPN_01617 1.1e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MFFGAFPN_01618 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
MFFGAFPN_01619 3.58e-51 ylmC - - S - - - sporulation protein
MFFGAFPN_01620 7.23e-201 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
MFFGAFPN_01621 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MFFGAFPN_01622 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MFFGAFPN_01623 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
MFFGAFPN_01624 1.49e-178 ylmH - - S - - - conserved protein, contains S4-like domain
MFFGAFPN_01625 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
MFFGAFPN_01626 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MFFGAFPN_01627 1.58e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
MFFGAFPN_01628 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MFFGAFPN_01629 1.01e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MFFGAFPN_01630 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MFFGAFPN_01631 3.05e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
MFFGAFPN_01632 4.21e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MFFGAFPN_01633 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MFFGAFPN_01634 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MFFGAFPN_01635 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
MFFGAFPN_01636 7.44e-183 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MFFGAFPN_01637 1.73e-220 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MFFGAFPN_01638 4.43e-162 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MFFGAFPN_01639 8.96e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MFFGAFPN_01641 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
MFFGAFPN_01642 6.01e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
MFFGAFPN_01643 2.15e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
MFFGAFPN_01644 3.76e-140 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
MFFGAFPN_01645 5.9e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
MFFGAFPN_01646 1.45e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
MFFGAFPN_01647 6.53e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
MFFGAFPN_01648 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
MFFGAFPN_01649 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
MFFGAFPN_01650 8.41e-202 yloC - - S - - - stress-induced protein
MFFGAFPN_01651 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
MFFGAFPN_01652 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MFFGAFPN_01653 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MFFGAFPN_01654 7.28e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MFFGAFPN_01655 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MFFGAFPN_01656 7.97e-108 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MFFGAFPN_01657 2.88e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MFFGAFPN_01658 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MFFGAFPN_01659 2.16e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MFFGAFPN_01660 3.54e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MFFGAFPN_01661 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MFFGAFPN_01662 3.92e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MFFGAFPN_01663 1.1e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MFFGAFPN_01664 2.83e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MFFGAFPN_01665 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MFFGAFPN_01666 3.65e-78 yloU - - S - - - protein conserved in bacteria
MFFGAFPN_01667 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
MFFGAFPN_01668 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
MFFGAFPN_01669 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
MFFGAFPN_01670 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MFFGAFPN_01671 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MFFGAFPN_01672 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MFFGAFPN_01673 1.31e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MFFGAFPN_01674 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MFFGAFPN_01675 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MFFGAFPN_01676 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MFFGAFPN_01677 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MFFGAFPN_01678 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MFFGAFPN_01679 1.67e-114 - - - - - - - -
MFFGAFPN_01680 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MFFGAFPN_01681 9.7e-309 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MFFGAFPN_01682 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MFFGAFPN_01683 9.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
MFFGAFPN_01684 9.77e-80 ylqD - - S - - - YlqD protein
MFFGAFPN_01685 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MFFGAFPN_01686 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MFFGAFPN_01687 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MFFGAFPN_01688 4.89e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MFFGAFPN_01689 2.89e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MFFGAFPN_01690 0.0 ylqG - - - - - - -
MFFGAFPN_01691 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
MFFGAFPN_01692 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MFFGAFPN_01693 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MFFGAFPN_01694 2.66e-217 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
MFFGAFPN_01695 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MFFGAFPN_01696 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MFFGAFPN_01697 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
MFFGAFPN_01698 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MFFGAFPN_01699 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MFFGAFPN_01700 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MFFGAFPN_01701 3.27e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MFFGAFPN_01702 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
MFFGAFPN_01703 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
MFFGAFPN_01704 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
MFFGAFPN_01705 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MFFGAFPN_01706 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
MFFGAFPN_01707 1.22e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MFFGAFPN_01708 7.27e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
MFFGAFPN_01709 9.18e-80 ylxF - - S - - - MgtE intracellular N domain
MFFGAFPN_01710 1.34e-313 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
MFFGAFPN_01711 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
MFFGAFPN_01712 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
MFFGAFPN_01713 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
MFFGAFPN_01714 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MFFGAFPN_01715 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MFFGAFPN_01716 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
MFFGAFPN_01717 1.12e-136 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
MFFGAFPN_01718 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
MFFGAFPN_01719 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
MFFGAFPN_01720 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
MFFGAFPN_01721 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MFFGAFPN_01722 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MFFGAFPN_01723 1.14e-255 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
MFFGAFPN_01724 2.21e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
MFFGAFPN_01725 1.43e-249 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MFFGAFPN_01726 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
MFFGAFPN_01727 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
MFFGAFPN_01728 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MFFGAFPN_01729 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MFFGAFPN_01730 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFFGAFPN_01731 6.62e-99 ylxL - - - - - - -
MFFGAFPN_01732 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MFFGAFPN_01733 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MFFGAFPN_01734 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MFFGAFPN_01735 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MFFGAFPN_01736 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MFFGAFPN_01737 1.36e-177 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MFFGAFPN_01738 1.33e-274 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MFFGAFPN_01739 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MFFGAFPN_01740 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MFFGAFPN_01741 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MFFGAFPN_01742 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MFFGAFPN_01743 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MFFGAFPN_01744 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
MFFGAFPN_01745 6.16e-63 ylxQ - - J - - - ribosomal protein
MFFGAFPN_01746 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MFFGAFPN_01747 7.83e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
MFFGAFPN_01748 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MFFGAFPN_01749 6.04e-220 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MFFGAFPN_01750 9.42e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MFFGAFPN_01751 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MFFGAFPN_01752 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MFFGAFPN_01753 3.71e-235 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
MFFGAFPN_01754 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
MFFGAFPN_01755 1.53e-56 ymxH - - S - - - YlmC YmxH family
MFFGAFPN_01756 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
MFFGAFPN_01757 9.94e-142 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MFFGAFPN_01758 1.66e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MFFGAFPN_01759 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MFFGAFPN_01760 1.57e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MFFGAFPN_01761 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MFFGAFPN_01762 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
MFFGAFPN_01763 2.36e-42 - - - S - - - YlzJ-like protein
MFFGAFPN_01764 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MFFGAFPN_01765 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
MFFGAFPN_01766 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MFFGAFPN_01767 7.78e-298 albE - - S - - - Peptidase M16
MFFGAFPN_01768 5.35e-306 ymfH - - S - - - zinc protease
MFFGAFPN_01769 5.2e-167 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MFFGAFPN_01770 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
MFFGAFPN_01771 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
MFFGAFPN_01772 3.05e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
MFFGAFPN_01773 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MFFGAFPN_01774 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
MFFGAFPN_01775 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MFFGAFPN_01776 4e-280 pbpX - - V - - - Beta-lactamase
MFFGAFPN_01777 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MFFGAFPN_01778 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
MFFGAFPN_01779 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
MFFGAFPN_01780 1.44e-253 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MFFGAFPN_01781 1.62e-275 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MFFGAFPN_01782 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MFFGAFPN_01783 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
MFFGAFPN_01784 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
MFFGAFPN_01785 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MFFGAFPN_01786 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MFFGAFPN_01787 3.04e-88 - - - S - - - Regulatory protein YrvL
MFFGAFPN_01789 3.24e-126 ymcC - - S - - - Membrane
MFFGAFPN_01790 1.2e-140 pksA - - K - - - Transcriptional regulator
MFFGAFPN_01791 4.02e-167 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
MFFGAFPN_01792 2.17e-207 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MFFGAFPN_01794 5.71e-237 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
MFFGAFPN_01795 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MFFGAFPN_01796 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
MFFGAFPN_01797 2.07e-301 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MFFGAFPN_01798 1.13e-312 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
MFFGAFPN_01799 1.38e-181 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
MFFGAFPN_01800 2.12e-174 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
MFFGAFPN_01801 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
MFFGAFPN_01802 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MFFGAFPN_01803 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
MFFGAFPN_01804 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
MFFGAFPN_01805 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
MFFGAFPN_01806 2.79e-294 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MFFGAFPN_01807 2.8e-81 ymzB - - - - - - -
MFFGAFPN_01808 5.38e-207 - - - S - - - Metallo-beta-lactamase superfamily
MFFGAFPN_01809 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
MFFGAFPN_01811 6.58e-162 ymaC - - S - - - Replication protein
MFFGAFPN_01812 6.98e-104 ymaD - - O - - - redox protein, regulator of disulfide bond formation
MFFGAFPN_01813 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
MFFGAFPN_01814 1.21e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MFFGAFPN_01816 5.41e-76 ymaF - - S - - - YmaF family
MFFGAFPN_01817 5.61e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MFFGAFPN_01818 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MFFGAFPN_01819 1.63e-31 - - - - - - - -
MFFGAFPN_01820 1.2e-30 ymzA - - - - - - -
MFFGAFPN_01821 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
MFFGAFPN_01822 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MFFGAFPN_01823 4.74e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MFFGAFPN_01824 2.24e-141 - - - - - - - -
MFFGAFPN_01825 9.94e-151 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MFFGAFPN_01826 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
MFFGAFPN_01827 4.47e-294 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MFFGAFPN_01828 1.37e-309 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MFFGAFPN_01829 2.85e-89 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
MFFGAFPN_01830 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MFFGAFPN_01831 4.61e-47 - - - L - - - Arm DNA-binding domain
MFFGAFPN_01832 9.44e-127 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 replicative DNA helicase
MFFGAFPN_01833 3.5e-30 - - - - - - - -
MFFGAFPN_01836 4.9e-66 - - - M - - - ArpU family transcriptional regulator
MFFGAFPN_01837 1.82e-31 - - - S - - - FRG
MFFGAFPN_01838 1.4e-86 - - - S - - - regulation of transcription, DNA-dependent
MFFGAFPN_01839 4.25e-25 - - - N - - - HicA toxin of bacterial toxin-antitoxin,
MFFGAFPN_01844 1.89e-63 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
MFFGAFPN_01845 6.85e-103 - - - L - - - phage terminase small subunit
MFFGAFPN_01846 1.04e-42 - - - S - - - Terminase
MFFGAFPN_01849 4.18e-14 - - - - - - - -
MFFGAFPN_01851 1.34e-81 - - - Q - - - Collagen triple helix repeat (20 copies)
MFFGAFPN_01852 9.6e-120 - - - M - - - Glycosyltransferase like family
MFFGAFPN_01853 1.17e-155 - - - H - - - Methionine biosynthesis protein MetW
MFFGAFPN_01854 6.07e-248 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
MFFGAFPN_01855 7.73e-275 - - - H - - - N-terminal domain of galactosyltransferase
MFFGAFPN_01857 2.9e-126 ynaD - - J - - - Acetyltransferase (GNAT) domain
MFFGAFPN_01859 2.82e-94 - - - S - - - CAAX protease self-immunity
MFFGAFPN_01860 2.38e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
MFFGAFPN_01861 3.39e-31 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
MFFGAFPN_01862 1.39e-145 - - - S - - - Domain of unknown function (DUF3885)
MFFGAFPN_01865 6.36e-103 - - - E - - - phosphoribosylanthranilate isomerase activity
MFFGAFPN_01866 9.04e-97 - - - S ko:K03824 - ko00000,ko01000 family acetyltransferase
MFFGAFPN_01867 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
MFFGAFPN_01868 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
MFFGAFPN_01869 5.85e-274 xylR - - GK - - - ROK family
MFFGAFPN_01870 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
MFFGAFPN_01871 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
MFFGAFPN_01872 2.06e-144 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
MFFGAFPN_01873 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MFFGAFPN_01874 2.93e-279 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MFFGAFPN_01875 2.24e-106 - - - S - - - Protein of unknown function (DUF2691)
MFFGAFPN_01876 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
MFFGAFPN_01877 7.54e-22 - - - - - - - -
MFFGAFPN_01880 2.75e-210 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MFFGAFPN_01882 5.34e-166 - - - S - - - Domain of unknown function, YrpD
MFFGAFPN_01885 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
MFFGAFPN_01886 8.92e-96 - - - - - - - -
MFFGAFPN_01887 1.81e-103 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
MFFGAFPN_01891 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
MFFGAFPN_01892 2.38e-251 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
MFFGAFPN_01893 9.64e-290 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
MFFGAFPN_01894 2.16e-197 yndG - - S - - - DoxX-like family
MFFGAFPN_01895 3.88e-146 - - - S - - - Domain of unknown function (DUF4166)
MFFGAFPN_01896 0.0 yndJ - - S - - - YndJ-like protein
MFFGAFPN_01898 6.58e-175 yndL - - S - - - Replication protein
MFFGAFPN_01899 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
MFFGAFPN_01900 2.89e-100 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MFFGAFPN_01901 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MFFGAFPN_01902 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MFFGAFPN_01903 2.29e-144 yneB - - L - - - resolvase
MFFGAFPN_01904 1.15e-43 ynzC - - S - - - UPF0291 protein
MFFGAFPN_01905 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MFFGAFPN_01906 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
MFFGAFPN_01907 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
MFFGAFPN_01908 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
MFFGAFPN_01909 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
MFFGAFPN_01910 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
MFFGAFPN_01911 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
MFFGAFPN_01912 1.82e-93 yneK - - S - - - Protein of unknown function (DUF2621)
MFFGAFPN_01913 3.34e-84 cotM - - O ko:K06335 - ko00000 Spore coat protein
MFFGAFPN_01914 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
MFFGAFPN_01915 3.27e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
MFFGAFPN_01916 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MFFGAFPN_01917 8.82e-119 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MFFGAFPN_01918 9.26e-10 - - - S - - - Fur-regulated basic protein B
MFFGAFPN_01920 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
MFFGAFPN_01921 1.4e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
MFFGAFPN_01922 1.63e-71 yneQ - - - - - - -
MFFGAFPN_01923 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
MFFGAFPN_01924 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MFFGAFPN_01925 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
MFFGAFPN_01926 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MFFGAFPN_01927 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MFFGAFPN_01928 1.82e-18 - - - - - - - -
MFFGAFPN_01929 8.74e-75 ynfC - - - - - - -
MFFGAFPN_01930 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
MFFGAFPN_01931 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
MFFGAFPN_01933 9.85e-317 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
MFFGAFPN_01934 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
MFFGAFPN_01935 9.97e-103 yngA - - S - - - membrane
MFFGAFPN_01936 2.25e-209 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MFFGAFPN_01937 2.01e-134 yngC - - S - - - membrane-associated protein
MFFGAFPN_01938 1.28e-296 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
MFFGAFPN_01939 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MFFGAFPN_01940 4.96e-174 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
MFFGAFPN_01941 6.73e-212 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
MFFGAFPN_01942 2.4e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
MFFGAFPN_01943 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
MFFGAFPN_01944 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MFFGAFPN_01945 7.28e-266 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
MFFGAFPN_01946 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
MFFGAFPN_01947 2.48e-83 yngL - - S - - - Protein of unknown function (DUF1360)
MFFGAFPN_01948 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
MFFGAFPN_01949 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFFGAFPN_01950 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFFGAFPN_01951 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFFGAFPN_01952 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFFGAFPN_01953 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
MFFGAFPN_01954 1.41e-242 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MFFGAFPN_01955 2.3e-311 yoeA - - V - - - MATE efflux family protein
MFFGAFPN_01956 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
MFFGAFPN_01958 3.26e-124 - - - L - - - Integrase
MFFGAFPN_01959 4.71e-47 yoeD - - G - - - Helix-turn-helix domain
MFFGAFPN_01960 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
MFFGAFPN_01961 3.57e-200 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
MFFGAFPN_01962 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MFFGAFPN_01963 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MFFGAFPN_01964 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
MFFGAFPN_01965 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
MFFGAFPN_01966 1.57e-260 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MFFGAFPN_01967 1.58e-184 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MFFGAFPN_01968 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MFFGAFPN_01969 3.77e-158 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MFFGAFPN_01970 9.05e-52 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
MFFGAFPN_01971 4.72e-169 yoxB - - - - - - -
MFFGAFPN_01972 2.05e-116 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MFFGAFPN_01973 1.7e-300 - - - S - - - Arylsulfotransferase (ASST)
MFFGAFPN_01974 2.75e-160 - 3.1.1.3 - I ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 Lipase (class 3)
MFFGAFPN_01975 1.84e-299 yoaB - - EGP - - - the major facilitator superfamily
MFFGAFPN_01976 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
MFFGAFPN_01977 3.36e-234 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFFGAFPN_01978 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MFFGAFPN_01979 7.24e-45 yoaF - - - - - - -
MFFGAFPN_01982 1.46e-19 - - - - - - - -
MFFGAFPN_01983 6.78e-61 - - - S - - - Protein of unknown function (DUF4025)
MFFGAFPN_01984 1.12e-289 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
MFFGAFPN_01985 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
MFFGAFPN_01986 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
MFFGAFPN_01987 4.22e-144 yoaK - - S - - - Membrane
MFFGAFPN_01988 8.29e-252 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
MFFGAFPN_01989 1.2e-169 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
MFFGAFPN_01992 3.54e-96 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
MFFGAFPN_01993 6.99e-181 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
MFFGAFPN_01995 3.86e-183 yoaP - - K - - - YoaP-like
MFFGAFPN_01996 3.01e-87 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
MFFGAFPN_01998 9.24e-114 - - - - - - - -
MFFGAFPN_01999 1.04e-217 yoaR - - V - - - vancomycin resistance protein
MFFGAFPN_02000 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
MFFGAFPN_02001 7.19e-41 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
MFFGAFPN_02002 1.63e-190 yoaT - - S - - - Protein of unknown function (DUF817)
MFFGAFPN_02003 7.78e-202 yoaU - - K - - - LysR substrate binding domain
MFFGAFPN_02004 1.24e-199 yoaV - - EG - - - EamA-like transporter family
MFFGAFPN_02005 1.61e-101 yoaW - - - - - - -
MFFGAFPN_02006 9.45e-145 lin0465 - - S - - - DJ-1/PfpI family
MFFGAFPN_02007 2.44e-213 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
MFFGAFPN_02010 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
MFFGAFPN_02011 1.07e-156 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
MFFGAFPN_02012 1e-47 - - - S - - - TM2 domain
MFFGAFPN_02013 7.63e-74 - - - K - - - Helix-turn-helix
MFFGAFPN_02016 7.44e-66 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
MFFGAFPN_02021 1.56e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
MFFGAFPN_02025 6.81e-66 - - - S - - - Tetratricopeptide repeat
MFFGAFPN_02026 2.51e-74 - - - J - - - tRNA cytidylyltransferase activity
MFFGAFPN_02034 8.49e-265 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MFFGAFPN_02036 5.26e-200 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MFFGAFPN_02037 2.36e-44 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MFFGAFPN_02039 6.35e-30 - - - - - - - -
MFFGAFPN_02041 5.21e-26 - - - - - - - -
MFFGAFPN_02042 8.94e-13 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MFFGAFPN_02043 3.93e-117 yokH - - G - - - SMI1 / KNR4 family
MFFGAFPN_02044 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
MFFGAFPN_02045 1.75e-69 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
MFFGAFPN_02046 1.18e-171 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
MFFGAFPN_02047 2.93e-180 - - - J - - - FR47-like protein
MFFGAFPN_02048 3.09e-127 yobS - - K - - - Transcriptional regulator
MFFGAFPN_02049 3.16e-168 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MFFGAFPN_02050 1.01e-110 - - - K - - - Bacterial transcription activator, effector binding domain
MFFGAFPN_02051 3.81e-225 yobV - - K - - - WYL domain
MFFGAFPN_02052 4.1e-118 yobW - - - - - - -
MFFGAFPN_02053 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
MFFGAFPN_02054 2.89e-151 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MFFGAFPN_02055 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
MFFGAFPN_02056 7.99e-180 - - - - - - - -
MFFGAFPN_02057 2.99e-119 yocC - - - - - - -
MFFGAFPN_02058 3.43e-234 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
MFFGAFPN_02059 3.28e-257 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
MFFGAFPN_02060 3.51e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFFGAFPN_02061 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFFGAFPN_02062 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
MFFGAFPN_02063 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
MFFGAFPN_02064 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MFFGAFPN_02065 1.42e-107 yocK - - T - - - general stress protein
MFFGAFPN_02066 1.23e-69 yocL - - - - - - -
MFFGAFPN_02067 5.79e-43 - - - - - - - -
MFFGAFPN_02068 1.1e-113 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MFFGAFPN_02069 2.94e-55 yozN - - - - - - -
MFFGAFPN_02070 1.83e-49 yocN - - - - - - -
MFFGAFPN_02071 2.17e-74 yozO - - S - - - Bacterial PH domain
MFFGAFPN_02072 1.91e-42 yozC - - - - - - -
MFFGAFPN_02073 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MFFGAFPN_02074 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
MFFGAFPN_02075 3.91e-211 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
MFFGAFPN_02076 3.57e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MFFGAFPN_02077 7.79e-213 yocS - - S ko:K03453 - ko00000 -transporter
MFFGAFPN_02078 4.29e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MFFGAFPN_02079 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MFFGAFPN_02080 0.0 yojO - - P - - - Von Willebrand factor
MFFGAFPN_02081 1.28e-205 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
MFFGAFPN_02082 6.01e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MFFGAFPN_02083 1.3e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MFFGAFPN_02084 1.13e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
MFFGAFPN_02085 4.31e-141 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MFFGAFPN_02087 5.9e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
MFFGAFPN_02088 1.01e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MFFGAFPN_02089 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
MFFGAFPN_02090 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
MFFGAFPN_02091 1.85e-58 - - - - - - - -
MFFGAFPN_02092 1.92e-206 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
MFFGAFPN_02093 7.43e-107 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
MFFGAFPN_02094 5.59e-14 - - - - - - - -
MFFGAFPN_02095 5.8e-252 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
MFFGAFPN_02096 1.46e-19 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
MFFGAFPN_02097 5.64e-84 iolK - - S - - - tautomerase
MFFGAFPN_02098 2.63e-73 yodB - - K - - - transcriptional
MFFGAFPN_02099 1.11e-139 yodC - - C - - - nitroreductase
MFFGAFPN_02100 8.86e-145 yahD - - S ko:K06999 - ko00000 Carboxylesterase
MFFGAFPN_02101 3.24e-221 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MFFGAFPN_02102 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
MFFGAFPN_02103 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MFFGAFPN_02104 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MFFGAFPN_02105 3.03e-166 yodH - - Q - - - Methyltransferase
MFFGAFPN_02106 4.86e-41 yodI - - - - - - -
MFFGAFPN_02107 7.71e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
MFFGAFPN_02108 3.4e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
MFFGAFPN_02109 2.08e-12 - - - - - - - -
MFFGAFPN_02110 1.17e-71 yodL - - S - - - YodL-like
MFFGAFPN_02111 1.64e-137 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MFFGAFPN_02112 1.49e-33 yozD - - S - - - YozD-like protein
MFFGAFPN_02114 1.29e-159 yodN - - - - - - -
MFFGAFPN_02115 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
MFFGAFPN_02116 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
MFFGAFPN_02117 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
MFFGAFPN_02118 1.84e-197 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
MFFGAFPN_02119 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
MFFGAFPN_02120 7.76e-152 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MFFGAFPN_02121 9.37e-159 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MFFGAFPN_02122 9.36e-317 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MFFGAFPN_02124 6.61e-183 yiiD - - K ko:K06323 - ko00000 acetyltransferase
MFFGAFPN_02125 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
MFFGAFPN_02126 8.72e-59 cgeC - - - ko:K06321 - ko00000 -
MFFGAFPN_02127 5.57e-86 cgeA - - - ko:K06319 - ko00000 -
MFFGAFPN_02128 1.2e-239 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
MFFGAFPN_02129 7.94e-271 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
MFFGAFPN_02130 1.17e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
MFFGAFPN_02131 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MFFGAFPN_02132 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MFFGAFPN_02133 4.14e-94 ypoP - - K - - - transcriptional
MFFGAFPN_02134 4.06e-289 mepA - - V - - - MATE efflux family protein
MFFGAFPN_02135 2.13e-40 ypmT - - S - - - Uncharacterized ympT
MFFGAFPN_02136 1.95e-128 ypmS - - S - - - protein conserved in bacteria
MFFGAFPN_02137 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
MFFGAFPN_02138 3.23e-139 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MFFGAFPN_02139 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
MFFGAFPN_02140 3.64e-310 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MFFGAFPN_02141 1.4e-236 yplP - - K - - - Transcriptional regulator
MFFGAFPN_02142 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
MFFGAFPN_02143 1.99e-144 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MFFGAFPN_02144 9.96e-124 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MFFGAFPN_02145 2.43e-201 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MFFGAFPN_02146 2.56e-120 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
MFFGAFPN_02147 3.47e-148 ypjP - - S - - - YpjP-like protein
MFFGAFPN_02148 9.79e-184 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
MFFGAFPN_02149 1.61e-97 yphP - - S - - - Belongs to the UPF0403 family
MFFGAFPN_02150 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
MFFGAFPN_02151 9.9e-205 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
MFFGAFPN_02152 3.3e-138 yagB - - S ko:K06950 - ko00000 phosphohydrolase
MFFGAFPN_02153 5.41e-115 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
MFFGAFPN_02154 1.28e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MFFGAFPN_02156 5.22e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MFFGAFPN_02157 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
MFFGAFPN_02158 1.17e-22 degR - - - - - - -
MFFGAFPN_02159 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
MFFGAFPN_02160 1.54e-37 ypeQ - - S - - - Zinc-finger
MFFGAFPN_02161 6.45e-173 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
MFFGAFPN_02162 3.27e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MFFGAFPN_02163 7.64e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
MFFGAFPN_02164 5.23e-05 - - - - ko:K06429 - ko00000 -
MFFGAFPN_02165 2.26e-213 ypcP - - L - - - 5'3' exonuclease
MFFGAFPN_02166 1.08e-11 - - - - - - - -
MFFGAFPN_02167 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
MFFGAFPN_02168 0.0 ypbR - - S - - - Dynamin family
MFFGAFPN_02169 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
MFFGAFPN_02170 2.07e-262 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
MFFGAFPN_02171 3.14e-294 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
MFFGAFPN_02172 2.34e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MFFGAFPN_02173 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MFFGAFPN_02174 5.8e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MFFGAFPN_02175 1.03e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
MFFGAFPN_02176 8.11e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
MFFGAFPN_02177 7.8e-238 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
MFFGAFPN_02178 2.08e-203 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MFFGAFPN_02179 7.67e-175 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFFGAFPN_02180 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
MFFGAFPN_02182 2.84e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MFFGAFPN_02183 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MFFGAFPN_02184 1.19e-128 ypsA - - S - - - Belongs to the UPF0398 family
MFFGAFPN_02185 1.98e-298 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
MFFGAFPN_02186 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MFFGAFPN_02187 5.3e-110 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
MFFGAFPN_02188 4.33e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MFFGAFPN_02189 8.72e-68 yppG - - S - - - YppG-like protein
MFFGAFPN_02190 9.21e-11 - - - S - - - YppF-like protein
MFFGAFPN_02191 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
MFFGAFPN_02194 5.3e-240 yppC - - S - - - Protein of unknown function (DUF2515)
MFFGAFPN_02195 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MFFGAFPN_02196 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MFFGAFPN_02197 1.43e-121 ypoC - - - - - - -
MFFGAFPN_02198 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MFFGAFPN_02199 1.9e-164 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
MFFGAFPN_02200 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
MFFGAFPN_02201 1.25e-284 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MFFGAFPN_02202 2.66e-102 ypmB - - S - - - protein conserved in bacteria
MFFGAFPN_02203 6.21e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
MFFGAFPN_02204 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MFFGAFPN_02205 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MFFGAFPN_02206 5.47e-200 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MFFGAFPN_02207 5.66e-193 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MFFGAFPN_02208 4.87e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MFFGAFPN_02209 7.46e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MFFGAFPN_02210 8.54e-268 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
MFFGAFPN_02211 1.89e-166 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
MFFGAFPN_02212 2.52e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
MFFGAFPN_02213 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MFFGAFPN_02214 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
MFFGAFPN_02215 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MFFGAFPN_02216 6.84e-183 ypjB - - S - - - sporulation protein
MFFGAFPN_02217 1.63e-125 ypjA - - S - - - membrane
MFFGAFPN_02218 3.31e-190 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
MFFGAFPN_02219 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
MFFGAFPN_02220 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
MFFGAFPN_02221 2.26e-99 ypiF - - S - - - Protein of unknown function (DUF2487)
MFFGAFPN_02222 7.45e-129 ypiB - - S - - - Belongs to the UPF0302 family
MFFGAFPN_02223 1.06e-298 ypiA - - S - - - COG0457 FOG TPR repeat
MFFGAFPN_02224 4.03e-301 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MFFGAFPN_02225 1.71e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
MFFGAFPN_02226 4.5e-259 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MFFGAFPN_02227 5.43e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MFFGAFPN_02228 3.12e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MFFGAFPN_02229 2.6e-149 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
MFFGAFPN_02230 3.59e-146 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
MFFGAFPN_02231 6.08e-230 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MFFGAFPN_02232 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MFFGAFPN_02233 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MFFGAFPN_02234 7.79e-261 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MFFGAFPN_02235 5.88e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MFFGAFPN_02236 2.13e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
MFFGAFPN_02237 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MFFGAFPN_02238 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MFFGAFPN_02239 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MFFGAFPN_02240 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MFFGAFPN_02241 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MFFGAFPN_02242 1.26e-130 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
MFFGAFPN_02243 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MFFGAFPN_02244 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MFFGAFPN_02245 8.71e-176 yphF - - - - - - -
MFFGAFPN_02246 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
MFFGAFPN_02247 7.69e-232 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MFFGAFPN_02248 5.72e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MFFGAFPN_02249 4.16e-38 ypzH - - - - - - -
MFFGAFPN_02250 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
MFFGAFPN_02251 2.73e-134 yphA - - - - - - -
MFFGAFPN_02252 1.13e-11 - - - S - - - YpzI-like protein
MFFGAFPN_02253 3.99e-236 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MFFGAFPN_02254 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MFFGAFPN_02255 5.8e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MFFGAFPN_02256 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
MFFGAFPN_02257 1.09e-142 ypfA - - M - - - Flagellar protein YcgR
MFFGAFPN_02258 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
MFFGAFPN_02259 1.99e-207 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
MFFGAFPN_02260 4.33e-154 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
MFFGAFPN_02261 6.04e-223 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
MFFGAFPN_02262 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MFFGAFPN_02263 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MFFGAFPN_02264 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
MFFGAFPN_02265 8.23e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
MFFGAFPN_02266 8.61e-143 ypbE - - M - - - Lysin motif
MFFGAFPN_02267 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
MFFGAFPN_02268 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
MFFGAFPN_02269 5.67e-258 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
MFFGAFPN_02270 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
MFFGAFPN_02271 6.2e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MFFGAFPN_02272 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFFGAFPN_02273 4.79e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MFFGAFPN_02274 1.49e-254 rsiX - - - - - - -
MFFGAFPN_02275 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MFFGAFPN_02276 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFFGAFPN_02277 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFFGAFPN_02278 1.34e-278 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MFFGAFPN_02279 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
MFFGAFPN_02280 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MFFGAFPN_02281 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MFFGAFPN_02282 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
MFFGAFPN_02283 1.78e-133 spmA - - S ko:K06373 - ko00000 Spore maturation protein
MFFGAFPN_02284 4.79e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MFFGAFPN_02285 6.13e-128 ypuI - - S - - - Protein of unknown function (DUF3907)
MFFGAFPN_02286 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MFFGAFPN_02287 4.5e-162 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MFFGAFPN_02288 5.92e-119 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
MFFGAFPN_02289 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFFGAFPN_02290 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MFFGAFPN_02291 1.27e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MFFGAFPN_02292 1.24e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
MFFGAFPN_02293 2.41e-259 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MFFGAFPN_02294 2.96e-72 ypuD - - - - - - -
MFFGAFPN_02295 1.18e-132 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MFFGAFPN_02296 7.41e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
MFFGAFPN_02297 1.01e-16 - - - S - - - SNARE associated Golgi protein
MFFGAFPN_02299 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MFFGAFPN_02300 6.29e-192 ypuA - - S - - - Secreted protein
MFFGAFPN_02301 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MFFGAFPN_02302 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
MFFGAFPN_02303 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
MFFGAFPN_02304 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
MFFGAFPN_02305 3.1e-244 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
MFFGAFPN_02306 5.52e-101 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
MFFGAFPN_02307 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
MFFGAFPN_02308 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
MFFGAFPN_02309 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFFGAFPN_02310 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MFFGAFPN_02311 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
MFFGAFPN_02312 3.37e-271 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MFFGAFPN_02313 5.66e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MFFGAFPN_02314 2.77e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
MFFGAFPN_02315 3.91e-214 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
MFFGAFPN_02316 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
MFFGAFPN_02317 2.64e-103 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
MFFGAFPN_02318 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MFFGAFPN_02319 3.73e-44 yqkK - - - - - - -
MFFGAFPN_02320 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
MFFGAFPN_02321 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
MFFGAFPN_02322 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
MFFGAFPN_02323 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
MFFGAFPN_02324 3.18e-77 ansR - - K - - - Transcriptional regulator
MFFGAFPN_02325 2.62e-283 yqxK - - L - - - DNA helicase
MFFGAFPN_02326 1.17e-119 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
MFFGAFPN_02327 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
MFFGAFPN_02328 2.65e-217 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
MFFGAFPN_02329 6.61e-26 yqkE - - S - - - Protein of unknown function (DUF3886)
MFFGAFPN_02330 1.88e-221 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MFFGAFPN_02331 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
MFFGAFPN_02332 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
MFFGAFPN_02333 9.67e-250 yqkA - - K - - - GrpB protein
MFFGAFPN_02334 5.51e-79 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
MFFGAFPN_02335 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
MFFGAFPN_02336 1.87e-65 yqiX - - S - - - YolD-like protein
MFFGAFPN_02337 4.03e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MFFGAFPN_02338 6.83e-288 yqjV - - G - - - Major Facilitator Superfamily
MFFGAFPN_02340 1.33e-95 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFFGAFPN_02341 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MFFGAFPN_02342 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
MFFGAFPN_02343 6.89e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MFFGAFPN_02344 1.33e-228 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MFFGAFPN_02345 1.13e-188 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MFFGAFPN_02346 0.0 rocB - - E - - - arginine degradation protein
MFFGAFPN_02347 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MFFGAFPN_02348 3.86e-188 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MFFGAFPN_02349 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MFFGAFPN_02350 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MFFGAFPN_02351 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MFFGAFPN_02352 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MFFGAFPN_02353 2.72e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MFFGAFPN_02354 1.77e-32 yqzJ - - - - - - -
MFFGAFPN_02355 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MFFGAFPN_02356 8.77e-184 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
MFFGAFPN_02357 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
MFFGAFPN_02358 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MFFGAFPN_02359 7.17e-99 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
MFFGAFPN_02361 2.41e-128 yqjB - - S - - - protein conserved in bacteria
MFFGAFPN_02362 9.33e-226 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
MFFGAFPN_02363 1.28e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MFFGAFPN_02364 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MFFGAFPN_02365 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MFFGAFPN_02366 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
MFFGAFPN_02367 1.21e-213 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MFFGAFPN_02368 6.23e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
MFFGAFPN_02369 3.03e-193 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
MFFGAFPN_02370 2.65e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MFFGAFPN_02371 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MFFGAFPN_02372 1.92e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MFFGAFPN_02373 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MFFGAFPN_02374 3.96e-254 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
MFFGAFPN_02375 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MFFGAFPN_02376 1.74e-198 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
MFFGAFPN_02377 0.0 bkdR - - KT - - - Transcriptional regulator
MFFGAFPN_02378 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
MFFGAFPN_02379 4.18e-207 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MFFGAFPN_02380 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
MFFGAFPN_02381 6.46e-265 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MFFGAFPN_02382 2.01e-267 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
MFFGAFPN_02383 5.67e-198 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
MFFGAFPN_02384 9.45e-280 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MFFGAFPN_02385 2.9e-169 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MFFGAFPN_02386 1.14e-138 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
MFFGAFPN_02387 4.74e-37 - - - - - - - -
MFFGAFPN_02388 2.78e-275 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MFFGAFPN_02390 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MFFGAFPN_02391 5.12e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
MFFGAFPN_02392 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MFFGAFPN_02393 1.53e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MFFGAFPN_02394 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
MFFGAFPN_02395 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MFFGAFPN_02396 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MFFGAFPN_02397 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MFFGAFPN_02398 4.13e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MFFGAFPN_02399 4.34e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MFFGAFPN_02400 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MFFGAFPN_02401 1.65e-88 yqhY - - S - - - protein conserved in bacteria
MFFGAFPN_02402 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MFFGAFPN_02403 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MFFGAFPN_02404 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
MFFGAFPN_02405 3.61e-147 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
MFFGAFPN_02406 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
MFFGAFPN_02407 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
MFFGAFPN_02408 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
MFFGAFPN_02409 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
MFFGAFPN_02410 6.93e-112 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
MFFGAFPN_02411 1.22e-218 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
MFFGAFPN_02412 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
MFFGAFPN_02413 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MFFGAFPN_02414 3.65e-250 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
MFFGAFPN_02415 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
MFFGAFPN_02416 1.14e-120 yqhR - - S - - - Conserved membrane protein YqhR
MFFGAFPN_02417 4.24e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
MFFGAFPN_02418 5.18e-81 yqhP - - - - - - -
MFFGAFPN_02419 5.75e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
MFFGAFPN_02420 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MFFGAFPN_02421 1.52e-202 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MFFGAFPN_02422 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
MFFGAFPN_02423 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MFFGAFPN_02424 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MFFGAFPN_02425 5.49e-261 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
MFFGAFPN_02426 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
MFFGAFPN_02427 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
MFFGAFPN_02428 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
MFFGAFPN_02429 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
MFFGAFPN_02430 9e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
MFFGAFPN_02431 7.4e-98 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
MFFGAFPN_02432 8e-156 yqxM - - - ko:K19433 - ko00000 -
MFFGAFPN_02433 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
MFFGAFPN_02434 3.33e-35 yqzE - - S - - - YqzE-like protein
MFFGAFPN_02435 3.24e-58 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
MFFGAFPN_02436 1.18e-45 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
MFFGAFPN_02437 3.45e-76 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
MFFGAFPN_02438 1.13e-92 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
MFFGAFPN_02439 4.39e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
MFFGAFPN_02440 8.73e-219 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
MFFGAFPN_02441 1.83e-256 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MFFGAFPN_02443 5.89e-231 yqxL - - P - - - Mg2 transporter protein
MFFGAFPN_02444 4.95e-306 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MFFGAFPN_02445 6.12e-193 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MFFGAFPN_02447 1.29e-83 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
MFFGAFPN_02448 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
MFFGAFPN_02449 7.54e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
MFFGAFPN_02450 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
MFFGAFPN_02451 7.34e-66 yqgV - - S - - - Thiamine-binding protein
MFFGAFPN_02452 2.3e-257 yqgU - - - - - - -
MFFGAFPN_02453 3.04e-283 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
MFFGAFPN_02454 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
MFFGAFPN_02455 3.28e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MFFGAFPN_02456 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
MFFGAFPN_02457 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
MFFGAFPN_02458 3.38e-14 yqgO - - - - - - -
MFFGAFPN_02459 1.88e-135 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MFFGAFPN_02460 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MFFGAFPN_02461 1.98e-257 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
MFFGAFPN_02463 3.42e-68 yqzD - - - - - - -
MFFGAFPN_02464 9e-93 yqzC - - S - - - YceG-like family
MFFGAFPN_02465 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MFFGAFPN_02466 9.78e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MFFGAFPN_02467 8.71e-201 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
MFFGAFPN_02468 7.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MFFGAFPN_02469 5.26e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MFFGAFPN_02470 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
MFFGAFPN_02471 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
MFFGAFPN_02472 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
MFFGAFPN_02473 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
MFFGAFPN_02474 2.74e-168 yqgB - - S - - - Protein of unknown function (DUF1189)
MFFGAFPN_02475 3.32e-62 yqfZ - - M ko:K06417 - ko00000 LysM domain
MFFGAFPN_02476 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MFFGAFPN_02477 2.04e-81 yqfX - - S - - - membrane
MFFGAFPN_02478 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
MFFGAFPN_02479 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
MFFGAFPN_02480 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MFFGAFPN_02481 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
MFFGAFPN_02482 2.98e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MFFGAFPN_02483 1.09e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MFFGAFPN_02484 4.45e-45 yqfQ - - S - - - YqfQ-like protein
MFFGAFPN_02485 8.66e-227 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MFFGAFPN_02486 6.25e-268 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MFFGAFPN_02487 2.41e-150 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MFFGAFPN_02488 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
MFFGAFPN_02489 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MFFGAFPN_02490 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MFFGAFPN_02491 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
MFFGAFPN_02492 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MFFGAFPN_02493 3.29e-144 ccpN - - K - - - CBS domain
MFFGAFPN_02494 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MFFGAFPN_02495 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MFFGAFPN_02496 1.24e-185 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MFFGAFPN_02497 5.29e-27 - - - S - - - YqzL-like protein
MFFGAFPN_02498 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MFFGAFPN_02499 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MFFGAFPN_02500 4.75e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
MFFGAFPN_02501 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MFFGAFPN_02502 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
MFFGAFPN_02504 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
MFFGAFPN_02505 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
MFFGAFPN_02506 2.07e-60 yqfC - - S - - - sporulation protein YqfC
MFFGAFPN_02507 4e-66 yqfB - - - - - - -
MFFGAFPN_02508 4.35e-192 yqfA - - S - - - UPF0365 protein
MFFGAFPN_02509 7.62e-290 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
MFFGAFPN_02510 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
MFFGAFPN_02511 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MFFGAFPN_02512 1.4e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
MFFGAFPN_02513 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
MFFGAFPN_02514 8.34e-180 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MFFGAFPN_02515 5.63e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
MFFGAFPN_02516 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MFFGAFPN_02517 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MFFGAFPN_02518 8.79e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MFFGAFPN_02519 9.53e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MFFGAFPN_02520 7.13e-277 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
MFFGAFPN_02521 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MFFGAFPN_02522 7.06e-70 yqxA - - S - - - Protein of unknown function (DUF3679)
MFFGAFPN_02523 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
MFFGAFPN_02524 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MFFGAFPN_02525 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MFFGAFPN_02526 4.06e-244 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MFFGAFPN_02527 2.36e-22 - - - S - - - YqzM-like protein
MFFGAFPN_02528 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MFFGAFPN_02529 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
MFFGAFPN_02530 3.85e-137 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
MFFGAFPN_02531 1.1e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MFFGAFPN_02532 9.8e-179 yqeM - - Q - - - Methyltransferase
MFFGAFPN_02533 6.61e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MFFGAFPN_02534 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
MFFGAFPN_02535 5.83e-140 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MFFGAFPN_02536 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
MFFGAFPN_02537 6.94e-200 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MFFGAFPN_02538 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MFFGAFPN_02539 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
MFFGAFPN_02541 9.11e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
MFFGAFPN_02542 7.68e-173 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
MFFGAFPN_02543 3.65e-132 yqeD - - S - - - SNARE associated Golgi protein
MFFGAFPN_02544 1.26e-215 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
MFFGAFPN_02545 9.38e-171 - - - - - - - -
MFFGAFPN_02546 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
MFFGAFPN_02547 1.1e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFFGAFPN_02548 0.0 - - - L ko:K06400 - ko00000 Recombinase
MFFGAFPN_02549 2.25e-220 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MFFGAFPN_02550 4.9e-146 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MFFGAFPN_02551 7.69e-160 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MFFGAFPN_02552 7.1e-252 - - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
MFFGAFPN_02553 1.29e-196 - - - E - - - TAP-like protein
MFFGAFPN_02554 2.84e-123 - - - K ko:K16137 - ko00000,ko03000 QacR-like protein, C-terminal region
MFFGAFPN_02555 2.91e-191 - - - K - - - Helix-turn-helix XRE-family like proteins
MFFGAFPN_02556 4.18e-283 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MFFGAFPN_02557 1.71e-33 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
MFFGAFPN_02558 2.83e-83 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFFGAFPN_02559 2.97e-70 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
MFFGAFPN_02560 4.88e-40 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
MFFGAFPN_02561 2.58e-80 - - - K - - - BetI-type transcriptional repressor, C-terminal
MFFGAFPN_02562 1.67e-177 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MFFGAFPN_02563 8.68e-120 - - - S - - - Tetratricopeptide repeat
MFFGAFPN_02566 1.3e-199 - - - S - - - Bacterial EndoU nuclease
MFFGAFPN_02567 5.46e-32 - - - S - - - SMI1-KNR4 cell-wall
MFFGAFPN_02568 2.55e-90 yokH - - G - - - SMI1 / KNR4 family
MFFGAFPN_02569 5.39e-70 - - - V - - - HNH endonuclease
MFFGAFPN_02570 4.06e-123 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
MFFGAFPN_02571 1.76e-33 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
MFFGAFPN_02572 8.88e-72 yqaS - - L - - - DNA packaging
MFFGAFPN_02573 0.000188 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MFFGAFPN_02574 2.54e-36 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
MFFGAFPN_02575 3.56e-08 - - - S - - - Bacillus cereus group antimicrobial protein
MFFGAFPN_02576 2.79e-29 yqaO - - S - - - Phage-like element PBSX protein XtrA
MFFGAFPN_02577 9.17e-205 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
MFFGAFPN_02578 4.53e-118 - - - K - - - Transcriptional regulator PadR-like family
MFFGAFPN_02579 7.18e-131 yqaC - - F - - - adenylate kinase activity
MFFGAFPN_02581 7.83e-123 xkdA - - E - - - IrrE N-terminal-like domain
MFFGAFPN_02582 7.88e-79 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFFGAFPN_02583 7.32e-306 yrkQ - - T - - - Histidine kinase
MFFGAFPN_02584 1.24e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
MFFGAFPN_02585 2.16e-282 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
MFFGAFPN_02586 6.33e-133 yrkN - - K - - - Acetyltransferase (GNAT) family
MFFGAFPN_02587 1.91e-124 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
MFFGAFPN_02588 3.13e-104 - - - S - - - Protein of unknown function with HXXEE motif
MFFGAFPN_02589 1.9e-149 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
MFFGAFPN_02590 3.2e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
MFFGAFPN_02591 2.07e-263 yrkH - - P - - - Rhodanese Homology Domain
MFFGAFPN_02592 1.88e-125 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
MFFGAFPN_02593 1.88e-106 yrkE - - O - - - DsrE/DsrF/DrsH-like family
MFFGAFPN_02594 4.38e-52 yrkD - - S - - - protein conserved in bacteria
MFFGAFPN_02595 4.45e-138 yrkC - - G - - - Cupin domain
MFFGAFPN_02596 1.39e-191 bltR - - K - - - helix_turn_helix, mercury resistance
MFFGAFPN_02597 6.23e-268 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
MFFGAFPN_02598 5.09e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
MFFGAFPN_02599 2.15e-299 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MFFGAFPN_02600 2.45e-23 - - - S - - - YrzO-like protein
MFFGAFPN_02601 8.49e-217 yrdR - - EG - - - EamA-like transporter family
MFFGAFPN_02602 2.42e-204 - - - K - - - Transcriptional regulator
MFFGAFPN_02603 3.02e-254 trkA - - P ko:K07222 - ko00000 Oxidoreductase
MFFGAFPN_02604 2.09e-213 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
MFFGAFPN_02605 1.75e-87 yodA - - S - - - tautomerase
MFFGAFPN_02606 1.77e-205 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
MFFGAFPN_02607 2.37e-290 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MFFGAFPN_02608 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
MFFGAFPN_02609 9.34e-176 azlC - - E - - - AzlC protein
MFFGAFPN_02610 4.13e-104 bkdR - - K - - - helix_turn_helix ASNC type
MFFGAFPN_02611 1.47e-59 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
MFFGAFPN_02612 1.32e-290 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MFFGAFPN_02613 2.11e-130 yrdC - - Q - - - Isochorismatase family
MFFGAFPN_02614 2.99e-71 - - - S - - - Protein of unknown function (DUF2568)
MFFGAFPN_02615 2.75e-116 yrdA - - S - - - DinB family
MFFGAFPN_02616 8.54e-212 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
MFFGAFPN_02617 4.42e-248 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MFFGAFPN_02619 3.41e-188 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MFFGAFPN_02620 1.61e-160 yrpD - - S - - - Domain of unknown function, YrpD
MFFGAFPN_02622 9.28e-170 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MFFGAFPN_02623 3.7e-123 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MFFGAFPN_02624 5.96e-240 yrpG - - C - - - Aldo/keto reductase family
MFFGAFPN_02625 2.63e-286 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
MFFGAFPN_02626 2.97e-210 yraN - - K - - - Transcriptional regulator
MFFGAFPN_02627 5.95e-263 yraM - - S - - - PrpF protein
MFFGAFPN_02628 3.31e-201 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MFFGAFPN_02629 4.11e-53 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFFGAFPN_02630 1.84e-195 - - - S - - - Alpha beta hydrolase
MFFGAFPN_02631 6.61e-80 - - - T - - - sh3 domain protein
MFFGAFPN_02632 1.05e-81 - - - T - - - sh3 domain protein
MFFGAFPN_02633 5.45e-86 - - - E - - - Glyoxalase-like domain
MFFGAFPN_02634 2e-48 yraG - - - ko:K06440 - ko00000 -
MFFGAFPN_02635 7.91e-83 yraF - - M - - - Spore coat protein
MFFGAFPN_02636 2.14e-282 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MFFGAFPN_02637 6.11e-36 yraE - - - ko:K06440 - ko00000 -
MFFGAFPN_02638 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
MFFGAFPN_02639 1.83e-67 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
MFFGAFPN_02640 1.76e-39 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
MFFGAFPN_02641 4.81e-253 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
MFFGAFPN_02642 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
MFFGAFPN_02643 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
MFFGAFPN_02644 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
MFFGAFPN_02645 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
MFFGAFPN_02646 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
MFFGAFPN_02647 4.41e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MFFGAFPN_02648 0.0 levR - - K - - - PTS system fructose IIA component
MFFGAFPN_02649 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
MFFGAFPN_02650 4.63e-136 yrhP - - E - - - LysE type translocator
MFFGAFPN_02651 1.98e-192 yrhO - - K - - - Archaeal transcriptional regulator TrmB
MFFGAFPN_02652 4.75e-112 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MFFGAFPN_02653 2.12e-192 rsiV - - S - - - Protein of unknown function (DUF3298)
MFFGAFPN_02654 0.0 oatA - - I - - - Acyltransferase family
MFFGAFPN_02655 2.67e-62 yrhK - - S - - - YrhK-like protein
MFFGAFPN_02656 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
MFFGAFPN_02657 1.12e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
MFFGAFPN_02658 3.68e-125 yrhH - - Q - - - methyltransferase
MFFGAFPN_02659 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
MFFGAFPN_02661 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
MFFGAFPN_02662 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
MFFGAFPN_02663 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
MFFGAFPN_02664 4.26e-103 yrhD - - S - - - Protein of unknown function (DUF1641)
MFFGAFPN_02665 6.93e-49 yrhC - - S - - - YrhC-like protein
MFFGAFPN_02666 8.55e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MFFGAFPN_02667 7.04e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
MFFGAFPN_02668 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MFFGAFPN_02669 8.44e-154 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
MFFGAFPN_02670 1.42e-35 yrzA - - S - - - Protein of unknown function (DUF2536)
MFFGAFPN_02671 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
MFFGAFPN_02672 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
MFFGAFPN_02673 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MFFGAFPN_02674 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MFFGAFPN_02675 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
MFFGAFPN_02676 7.67e-223 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
MFFGAFPN_02677 1.4e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
MFFGAFPN_02678 7.19e-240 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MFFGAFPN_02679 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
MFFGAFPN_02680 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MFFGAFPN_02681 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
MFFGAFPN_02682 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MFFGAFPN_02683 8.81e-242 yrrI - - S - - - AI-2E family transporter
MFFGAFPN_02684 1.89e-169 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MFFGAFPN_02685 1.28e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MFFGAFPN_02686 6.53e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFFGAFPN_02687 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFFGAFPN_02688 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
MFFGAFPN_02689 8.4e-42 yrzR - - - - - - -
MFFGAFPN_02690 6.85e-106 yrrD - - S - - - protein conserved in bacteria
MFFGAFPN_02691 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MFFGAFPN_02692 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
MFFGAFPN_02693 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MFFGAFPN_02694 1.09e-271 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MFFGAFPN_02695 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
MFFGAFPN_02696 8.5e-304 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MFFGAFPN_02697 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MFFGAFPN_02698 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MFFGAFPN_02699 2.11e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MFFGAFPN_02701 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
MFFGAFPN_02702 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MFFGAFPN_02703 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MFFGAFPN_02704 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MFFGAFPN_02705 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MFFGAFPN_02706 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
MFFGAFPN_02707 3.1e-112 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
MFFGAFPN_02708 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MFFGAFPN_02709 5.53e-65 yrzD - - S - - - Post-transcriptional regulator
MFFGAFPN_02710 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MFFGAFPN_02711 2.12e-145 yrbG - - S - - - membrane
MFFGAFPN_02712 1.07e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
MFFGAFPN_02713 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
MFFGAFPN_02714 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MFFGAFPN_02715 3.49e-247 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MFFGAFPN_02716 4.13e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
MFFGAFPN_02717 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MFFGAFPN_02718 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MFFGAFPN_02719 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
MFFGAFPN_02720 0.0 csbX - - EGP - - - the major facilitator superfamily
MFFGAFPN_02721 4.59e-247 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
MFFGAFPN_02722 1.57e-150 yrzF - - T - - - serine threonine protein kinase
MFFGAFPN_02724 4.41e-68 - - - S - - - Family of unknown function (DUF5412)
MFFGAFPN_02725 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
MFFGAFPN_02726 4.99e-164 yebC - - K - - - transcriptional regulatory protein
MFFGAFPN_02727 7.28e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MFFGAFPN_02728 2.43e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
MFFGAFPN_02729 7.94e-273 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MFFGAFPN_02730 4.34e-203 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
MFFGAFPN_02731 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
MFFGAFPN_02732 1.66e-290 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MFFGAFPN_02733 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
MFFGAFPN_02734 4.1e-208 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
MFFGAFPN_02735 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
MFFGAFPN_02736 7.94e-308 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MFFGAFPN_02737 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
MFFGAFPN_02738 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MFFGAFPN_02739 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
MFFGAFPN_02740 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MFFGAFPN_02741 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
MFFGAFPN_02742 1.83e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
MFFGAFPN_02743 2.91e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
MFFGAFPN_02744 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MFFGAFPN_02745 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
MFFGAFPN_02746 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MFFGAFPN_02747 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
MFFGAFPN_02748 8.35e-163 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
MFFGAFPN_02749 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
MFFGAFPN_02750 7.73e-214 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
MFFGAFPN_02751 1.28e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MFFGAFPN_02752 2.22e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MFFGAFPN_02753 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MFFGAFPN_02754 1.53e-35 - - - - - - - -
MFFGAFPN_02755 1.38e-251 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MFFGAFPN_02756 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
MFFGAFPN_02757 4.11e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
MFFGAFPN_02758 2.14e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
MFFGAFPN_02759 7.14e-184 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
MFFGAFPN_02760 7.63e-221 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MFFGAFPN_02761 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
MFFGAFPN_02762 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MFFGAFPN_02763 6.77e-116 ysxD - - - - - - -
MFFGAFPN_02764 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MFFGAFPN_02765 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MFFGAFPN_02766 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
MFFGAFPN_02767 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MFFGAFPN_02768 2.54e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MFFGAFPN_02769 3.19e-239 ysoA - - H - - - Tetratricopeptide repeat
MFFGAFPN_02770 4.23e-147 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MFFGAFPN_02771 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MFFGAFPN_02772 2.13e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MFFGAFPN_02773 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MFFGAFPN_02774 3.91e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MFFGAFPN_02775 7.17e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
MFFGAFPN_02776 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
MFFGAFPN_02777 4.54e-105 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
MFFGAFPN_02778 1.01e-184 ysnF - - S - - - protein conserved in bacteria
MFFGAFPN_02780 6.72e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
MFFGAFPN_02781 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MFFGAFPN_02782 3.53e-171 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MFFGAFPN_02783 1.62e-255 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
MFFGAFPN_02784 4.49e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MFFGAFPN_02785 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
MFFGAFPN_02786 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
MFFGAFPN_02787 2.65e-102 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
MFFGAFPN_02788 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
MFFGAFPN_02789 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
MFFGAFPN_02790 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
MFFGAFPN_02791 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
MFFGAFPN_02792 6.56e-274 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MFFGAFPN_02793 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MFFGAFPN_02794 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MFFGAFPN_02795 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
MFFGAFPN_02797 2.04e-226 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
MFFGAFPN_02798 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
MFFGAFPN_02799 8.95e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
MFFGAFPN_02800 1.21e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
MFFGAFPN_02801 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MFFGAFPN_02802 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
MFFGAFPN_02803 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MFFGAFPN_02804 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
MFFGAFPN_02805 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
MFFGAFPN_02806 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MFFGAFPN_02807 2.84e-213 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MFFGAFPN_02808 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MFFGAFPN_02809 3e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MFFGAFPN_02810 2.11e-169 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MFFGAFPN_02811 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
MFFGAFPN_02812 7.2e-260 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
MFFGAFPN_02813 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
MFFGAFPN_02814 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
MFFGAFPN_02815 5.13e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
MFFGAFPN_02817 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
MFFGAFPN_02818 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
MFFGAFPN_02819 4.28e-190 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
MFFGAFPN_02820 6.77e-219 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
MFFGAFPN_02821 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
MFFGAFPN_02822 2.24e-283 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MFFGAFPN_02823 7.07e-186 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
MFFGAFPN_02824 2.32e-168 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MFFGAFPN_02825 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
MFFGAFPN_02826 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
MFFGAFPN_02827 9.92e-242 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
MFFGAFPN_02828 8.77e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
MFFGAFPN_02829 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
MFFGAFPN_02830 5.19e-59 ysdA - - S - - - Membrane
MFFGAFPN_02831 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MFFGAFPN_02832 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MFFGAFPN_02833 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MFFGAFPN_02835 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MFFGAFPN_02836 2.08e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MFFGAFPN_02837 3.39e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
MFFGAFPN_02838 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFFGAFPN_02839 1.2e-190 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
MFFGAFPN_02840 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MFFGAFPN_02841 5.98e-206 ytxC - - S - - - YtxC-like family
MFFGAFPN_02842 2.3e-142 ytxB - - S - - - SNARE associated Golgi protein
MFFGAFPN_02843 1.22e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MFFGAFPN_02844 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
MFFGAFPN_02845 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MFFGAFPN_02846 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MFFGAFPN_02847 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MFFGAFPN_02848 9.85e-88 ytcD - - K - - - Transcriptional regulator
MFFGAFPN_02849 4.57e-254 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
MFFGAFPN_02850 4.54e-205 ytbE - - S - - - reductase
MFFGAFPN_02851 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MFFGAFPN_02852 5.63e-137 ytaF - - P - - - Probably functions as a manganese efflux pump
MFFGAFPN_02853 3.88e-200 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MFFGAFPN_02854 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MFFGAFPN_02855 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
MFFGAFPN_02856 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFFGAFPN_02857 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
MFFGAFPN_02858 6.53e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
MFFGAFPN_02859 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MFFGAFPN_02860 9.38e-95 ytwI - - S - - - membrane
MFFGAFPN_02861 7.83e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
MFFGAFPN_02862 4.68e-82 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
MFFGAFPN_02863 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MFFGAFPN_02864 1.62e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MFFGAFPN_02865 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MFFGAFPN_02866 2.17e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MFFGAFPN_02867 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
MFFGAFPN_02868 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MFFGAFPN_02869 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
MFFGAFPN_02870 5.98e-111 ytrI - - - - - - -
MFFGAFPN_02871 1.15e-39 - - - - - - - -
MFFGAFPN_02872 1.02e-229 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
MFFGAFPN_02873 2.15e-63 ytpI - - S - - - YtpI-like protein
MFFGAFPN_02874 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
MFFGAFPN_02875 2.24e-206 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
MFFGAFPN_02876 1.41e-304 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
MFFGAFPN_02877 4.66e-164 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
MFFGAFPN_02878 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MFFGAFPN_02879 2.14e-62 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
MFFGAFPN_02880 1.7e-234 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MFFGAFPN_02881 5.43e-182 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MFFGAFPN_02882 7.89e-154 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MFFGAFPN_02883 1.66e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MFFGAFPN_02884 6.27e-187 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MFFGAFPN_02885 9.11e-195 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MFFGAFPN_02886 8.39e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MFFGAFPN_02887 1.37e-220 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
MFFGAFPN_02888 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
MFFGAFPN_02889 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFFGAFPN_02891 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
MFFGAFPN_02892 3.03e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MFFGAFPN_02893 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
MFFGAFPN_02894 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MFFGAFPN_02895 1.08e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
MFFGAFPN_02896 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MFFGAFPN_02897 1.06e-94 ytfJ - - S - - - Sporulation protein YtfJ
MFFGAFPN_02898 8.34e-149 ytfI - - S - - - Protein of unknown function (DUF2953)
MFFGAFPN_02899 4.08e-112 yteJ - - S - - - RDD family
MFFGAFPN_02900 2.79e-229 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
MFFGAFPN_02901 4.85e-189 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MFFGAFPN_02902 0.0 ytcJ - - S - - - amidohydrolase
MFFGAFPN_02903 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MFFGAFPN_02904 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
MFFGAFPN_02905 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MFFGAFPN_02906 4.55e-265 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MFFGAFPN_02907 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MFFGAFPN_02908 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MFFGAFPN_02909 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MFFGAFPN_02910 1.2e-141 yttP - - K - - - Transcriptional regulator
MFFGAFPN_02911 3.24e-113 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MFFGAFPN_02912 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
MFFGAFPN_02913 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MFFGAFPN_02915 2.63e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MFFGAFPN_02916 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MFFGAFPN_02917 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MFFGAFPN_02918 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
MFFGAFPN_02919 2.65e-292 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
MFFGAFPN_02920 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
MFFGAFPN_02921 5.62e-186 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
MFFGAFPN_02922 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MFFGAFPN_02923 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MFFGAFPN_02924 6.39e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
MFFGAFPN_02925 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
MFFGAFPN_02926 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MFFGAFPN_02927 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MFFGAFPN_02928 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MFFGAFPN_02929 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MFFGAFPN_02930 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
MFFGAFPN_02931 3.17e-75 ytpP - - CO - - - Thioredoxin
MFFGAFPN_02932 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
MFFGAFPN_02933 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
MFFGAFPN_02934 6.75e-67 ytzB - - S - - - small secreted protein
MFFGAFPN_02935 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
MFFGAFPN_02936 5.09e-192 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MFFGAFPN_02937 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MFFGAFPN_02938 9.51e-61 ytzH - - S - - - YtzH-like protein
MFFGAFPN_02939 3.02e-192 ytmP - - M - - - Phosphotransferase
MFFGAFPN_02940 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MFFGAFPN_02941 9.05e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MFFGAFPN_02942 4.04e-211 ytlQ - - - - - - -
MFFGAFPN_02943 4.29e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MFFGAFPN_02944 8.59e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MFFGAFPN_02945 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
MFFGAFPN_02946 7.02e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
MFFGAFPN_02947 3.51e-255 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
MFFGAFPN_02948 5.66e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MFFGAFPN_02949 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
MFFGAFPN_02950 7.43e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MFFGAFPN_02951 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MFFGAFPN_02952 9.93e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
MFFGAFPN_02953 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
MFFGAFPN_02954 2.14e-36 yteV - - S - - - Sporulation protein Cse60
MFFGAFPN_02955 1.55e-149 yteU - - S - - - Integral membrane protein
MFFGAFPN_02956 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
MFFGAFPN_02957 4.78e-94 yteS - - G - - - transport
MFFGAFPN_02958 1.54e-274 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
MFFGAFPN_02959 2.27e-221 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
MFFGAFPN_02960 0.0 ytdP - - K - - - Transcriptional regulator
MFFGAFPN_02961 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
MFFGAFPN_02962 1.02e-191 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
MFFGAFPN_02963 8.64e-176 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
MFFGAFPN_02964 3.75e-287 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MFFGAFPN_02965 1.53e-242 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MFFGAFPN_02966 1.09e-158 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MFFGAFPN_02967 1.1e-276 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MFFGAFPN_02968 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MFFGAFPN_02969 5.28e-178 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MFFGAFPN_02970 9.68e-221 - - - S - - - Acetyl xylan esterase (AXE1)
MFFGAFPN_02971 2.17e-242 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MFFGAFPN_02972 2.12e-311 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MFFGAFPN_02973 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFFGAFPN_02974 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MFFGAFPN_02975 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
MFFGAFPN_02976 7.08e-68 ytwF - - P - - - Sulfurtransferase
MFFGAFPN_02977 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MFFGAFPN_02978 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
MFFGAFPN_02979 7.09e-179 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MFFGAFPN_02980 4.94e-268 yttB - - EGP - - - Major facilitator superfamily
MFFGAFPN_02981 1.64e-77 yttA - - S - - - Pfam Transposase IS66
MFFGAFPN_02982 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
MFFGAFPN_02983 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
MFFGAFPN_02984 2.15e-237 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
MFFGAFPN_02985 1.57e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFFGAFPN_02986 1.62e-295 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
MFFGAFPN_02987 1.02e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFGAFPN_02988 5.96e-180 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
MFFGAFPN_02989 1.72e-192 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MFFGAFPN_02990 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFGAFPN_02991 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
MFFGAFPN_02993 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
MFFGAFPN_02994 2.35e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
MFFGAFPN_02995 2.26e-135 ytqB - - J - - - Putative rRNA methylase
MFFGAFPN_02996 5.61e-275 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
MFFGAFPN_02997 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
MFFGAFPN_02998 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MFFGAFPN_02999 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MFFGAFPN_03000 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MFFGAFPN_03001 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MFFGAFPN_03002 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MFFGAFPN_03003 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
MFFGAFPN_03004 1.11e-189 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MFFGAFPN_03005 1.79e-238 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MFFGAFPN_03006 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MFFGAFPN_03007 1.09e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MFFGAFPN_03008 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
MFFGAFPN_03009 1.59e-81 ytkC - - S - - - Bacteriophage holin family
MFFGAFPN_03010 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MFFGAFPN_03012 6.79e-95 ytkA - - S - - - YtkA-like
MFFGAFPN_03013 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MFFGAFPN_03014 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
MFFGAFPN_03015 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MFFGAFPN_03016 4.32e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
MFFGAFPN_03017 4.02e-239 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MFFGAFPN_03018 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
MFFGAFPN_03019 1.95e-193 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MFFGAFPN_03020 6.39e-297 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MFFGAFPN_03021 1.5e-179 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MFFGAFPN_03022 1.13e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MFFGAFPN_03023 7.07e-273 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MFFGAFPN_03024 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MFFGAFPN_03025 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MFFGAFPN_03026 9.85e-197 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MFFGAFPN_03027 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MFFGAFPN_03028 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
MFFGAFPN_03029 3.53e-168 yteA - - T - - - COG1734 DnaK suppressor protein
MFFGAFPN_03030 1.91e-193 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
MFFGAFPN_03031 8.28e-310 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MFFGAFPN_03032 3.15e-230 ytcB - - M - - - NAD-dependent epimerase dehydratase
MFFGAFPN_03033 1.19e-296 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
MFFGAFPN_03035 2.82e-262 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
MFFGAFPN_03036 1.75e-276 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
MFFGAFPN_03037 2.13e-259 cotI - - S ko:K06331 - ko00000 Spore coat protein
MFFGAFPN_03038 3.28e-100 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
MFFGAFPN_03039 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MFFGAFPN_03040 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
MFFGAFPN_03041 6.16e-237 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
MFFGAFPN_03042 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MFFGAFPN_03043 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MFFGAFPN_03065 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
MFFGAFPN_03066 7.22e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
MFFGAFPN_03067 9.87e-122 - - - M - - - FR47-like protein
MFFGAFPN_03068 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
MFFGAFPN_03069 4.82e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
MFFGAFPN_03070 1.95e-109 yuaE - - S - - - DinB superfamily
MFFGAFPN_03071 2.02e-137 yuaD - - - - - - -
MFFGAFPN_03072 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
MFFGAFPN_03073 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MFFGAFPN_03074 2.9e-122 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
MFFGAFPN_03075 5.83e-118 yuaB - - - - - - -
MFFGAFPN_03076 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
MFFGAFPN_03077 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
MFFGAFPN_03078 3.31e-52 yubF - - S - - - yiaA/B two helix domain
MFFGAFPN_03079 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MFFGAFPN_03080 0.0 yubD - - P - - - Major Facilitator Superfamily
MFFGAFPN_03081 1.88e-111 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
MFFGAFPN_03083 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MFFGAFPN_03084 2.56e-254 yubA - - S - - - transporter activity
MFFGAFPN_03085 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
MFFGAFPN_03086 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
MFFGAFPN_03087 2.02e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
MFFGAFPN_03088 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MFFGAFPN_03089 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MFFGAFPN_03090 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
MFFGAFPN_03091 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MFFGAFPN_03092 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MFFGAFPN_03093 3.24e-295 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MFFGAFPN_03094 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MFFGAFPN_03095 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
MFFGAFPN_03096 1.44e-47 - - - - - - - -
MFFGAFPN_03097 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
MFFGAFPN_03098 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MFFGAFPN_03099 1.03e-299 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MFFGAFPN_03100 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
MFFGAFPN_03101 1.58e-50 - - - - - - - -
MFFGAFPN_03102 2.12e-70 mstX - - S - - - Membrane-integrating protein Mistic
MFFGAFPN_03103 2.06e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
MFFGAFPN_03104 1.72e-94 yugN - - S - - - YugN-like family
MFFGAFPN_03106 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MFFGAFPN_03107 9.22e-290 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
MFFGAFPN_03108 2.34e-286 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
MFFGAFPN_03109 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
MFFGAFPN_03110 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
MFFGAFPN_03111 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
MFFGAFPN_03112 6.74e-112 alaR - - K - - - Transcriptional regulator
MFFGAFPN_03113 4.03e-200 yugF - - I - - - Hydrolase
MFFGAFPN_03114 6.22e-52 yugE - - S - - - Domain of unknown function (DUF1871)
MFFGAFPN_03115 6.99e-288 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MFFGAFPN_03116 1.06e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFFGAFPN_03117 1.44e-90 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
MFFGAFPN_03118 8.49e-150 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
MFFGAFPN_03120 8.9e-242 yuxJ - - EGP - - - Major facilitator superfamily
MFFGAFPN_03121 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
MFFGAFPN_03122 3.31e-98 yuxK - - S - - - protein conserved in bacteria
MFFGAFPN_03123 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
MFFGAFPN_03124 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MFFGAFPN_03125 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
MFFGAFPN_03126 3.66e-253 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
MFFGAFPN_03127 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MFFGAFPN_03128 6.39e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MFFGAFPN_03129 1.71e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MFFGAFPN_03130 7.99e-309 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
MFFGAFPN_03131 1.73e-22 - - - - - - - -
MFFGAFPN_03132 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MFFGAFPN_03133 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MFFGAFPN_03134 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MFFGAFPN_03135 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MFFGAFPN_03136 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MFFGAFPN_03137 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MFFGAFPN_03138 5.97e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
MFFGAFPN_03139 7.81e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
MFFGAFPN_03140 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFFGAFPN_03141 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFFGAFPN_03142 1.84e-164 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFFGAFPN_03144 2.83e-209 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
MFFGAFPN_03145 6.29e-10 - - - S - - - DegQ (SacQ) family
MFFGAFPN_03146 8.73e-09 yuzC - - - - - - -
MFFGAFPN_03147 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
MFFGAFPN_03149 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MFFGAFPN_03150 3.27e-134 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
MFFGAFPN_03151 2.19e-87 - - - S - - - Protein of unknown function (DUF1694)
MFFGAFPN_03152 1.57e-50 yueH - - S - - - YueH-like protein
MFFGAFPN_03153 7.15e-43 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
MFFGAFPN_03154 1.35e-244 yueF - - S - - - transporter activity
MFFGAFPN_03155 7.71e-91 - - - S - - - Protein of unknown function (DUF2283)
MFFGAFPN_03156 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
MFFGAFPN_03157 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
MFFGAFPN_03158 2.9e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFFGAFPN_03159 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
MFFGAFPN_03160 0.0 yueB - - S - - - type VII secretion protein EsaA
MFFGAFPN_03161 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MFFGAFPN_03162 4.28e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
MFFGAFPN_03163 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
MFFGAFPN_03164 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
MFFGAFPN_03165 3.45e-291 yukF - - QT - - - Transcriptional regulator
MFFGAFPN_03166 2.83e-262 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
MFFGAFPN_03167 3.44e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
MFFGAFPN_03168 2.02e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
MFFGAFPN_03169 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFFGAFPN_03170 1.1e-228 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
MFFGAFPN_03171 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
MFFGAFPN_03172 1.73e-289 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
MFFGAFPN_03173 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MFFGAFPN_03174 1.04e-211 eSD - - S ko:K07017 - ko00000 Putative esterase
MFFGAFPN_03175 2.76e-156 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
MFFGAFPN_03176 6.84e-124 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
MFFGAFPN_03177 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
MFFGAFPN_03178 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MFFGAFPN_03179 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
MFFGAFPN_03180 2.69e-150 yuiC - - S - - - protein conserved in bacteria
MFFGAFPN_03181 1.97e-46 yuiB - - S - - - Putative membrane protein
MFFGAFPN_03182 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MFFGAFPN_03183 1.92e-239 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
MFFGAFPN_03185 4.51e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MFFGAFPN_03186 5.51e-147 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
MFFGAFPN_03187 1.39e-115 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFFGAFPN_03188 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
MFFGAFPN_03189 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MFFGAFPN_03190 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MFFGAFPN_03191 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
MFFGAFPN_03192 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MFFGAFPN_03193 1.29e-72 yuzD - - S - - - protein conserved in bacteria
MFFGAFPN_03194 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
MFFGAFPN_03195 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
MFFGAFPN_03196 8.58e-220 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MFFGAFPN_03197 2.4e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MFFGAFPN_03198 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MFFGAFPN_03199 4.63e-255 yutH - - S - - - Spore coat protein
MFFGAFPN_03200 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
MFFGAFPN_03201 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MFFGAFPN_03202 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
MFFGAFPN_03203 3.2e-63 yutD - - S - - - protein conserved in bacteria
MFFGAFPN_03204 9.45e-145 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MFFGAFPN_03205 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MFFGAFPN_03206 2.66e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
MFFGAFPN_03207 4.25e-172 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
MFFGAFPN_03208 5.67e-64 yunC - - S - - - Domain of unknown function (DUF1805)
MFFGAFPN_03209 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MFFGAFPN_03210 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
MFFGAFPN_03211 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
MFFGAFPN_03212 1.07e-79 yunG - - - - - - -
MFFGAFPN_03213 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MFFGAFPN_03214 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
MFFGAFPN_03215 3.29e-297 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
MFFGAFPN_03216 9.11e-283 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
MFFGAFPN_03217 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MFFGAFPN_03218 1.72e-71 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
MFFGAFPN_03219 8.45e-123 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MFFGAFPN_03220 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MFFGAFPN_03221 5.2e-189 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MFFGAFPN_03222 3.58e-142 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
MFFGAFPN_03223 3.56e-234 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MFFGAFPN_03225 1.21e-305 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MFFGAFPN_03226 2.79e-293 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MFFGAFPN_03227 7.63e-217 bsn - - L - - - Ribonuclease
MFFGAFPN_03228 9.87e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MFFGAFPN_03229 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
MFFGAFPN_03230 7.86e-208 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
MFFGAFPN_03231 1.94e-216 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
MFFGAFPN_03232 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MFFGAFPN_03233 2.87e-307 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
MFFGAFPN_03234 5.27e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MFFGAFPN_03235 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
MFFGAFPN_03236 1.85e-264 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
MFFGAFPN_03238 3.35e-56 - - - - - - - -
MFFGAFPN_03239 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
MFFGAFPN_03240 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
MFFGAFPN_03241 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MFFGAFPN_03242 7.43e-313 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
MFFGAFPN_03243 4.46e-182 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MFFGAFPN_03244 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MFFGAFPN_03245 8.33e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
MFFGAFPN_03246 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
MFFGAFPN_03247 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MFFGAFPN_03248 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
MFFGAFPN_03249 2e-73 yusE - - CO - - - Thioredoxin
MFFGAFPN_03250 7.62e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
MFFGAFPN_03251 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
MFFGAFPN_03252 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MFFGAFPN_03253 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
MFFGAFPN_03254 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
MFFGAFPN_03255 7.74e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
MFFGAFPN_03256 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
MFFGAFPN_03257 2.86e-14 - - - S - - - YuzL-like protein
MFFGAFPN_03258 5.98e-212 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
MFFGAFPN_03259 2.23e-54 - - - - - - - -
MFFGAFPN_03260 2.48e-69 yusN - - M - - - Coat F domain
MFFGAFPN_03261 3.83e-99 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
MFFGAFPN_03262 0.0 yusP - - P - - - Major facilitator superfamily
MFFGAFPN_03263 2.93e-85 yusQ - - S - - - Tautomerase enzyme
MFFGAFPN_03264 8.6e-139 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MFFGAFPN_03265 2.94e-204 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
MFFGAFPN_03266 3.66e-64 yusU - - S - - - Protein of unknown function (DUF2573)
MFFGAFPN_03267 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MFFGAFPN_03268 2.01e-87 - - - S - - - YusW-like protein
MFFGAFPN_03269 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
MFFGAFPN_03270 1.1e-196 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MFFGAFPN_03271 1.77e-103 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
MFFGAFPN_03272 5.09e-301 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFFGAFPN_03273 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFFGAFPN_03274 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFFGAFPN_03275 3.06e-204 yuxN - - K - - - Transcriptional regulator
MFFGAFPN_03276 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MFFGAFPN_03277 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
MFFGAFPN_03278 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
MFFGAFPN_03279 2.9e-253 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
MFFGAFPN_03280 3.48e-249 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
MFFGAFPN_03281 9.39e-141 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFFGAFPN_03282 3.34e-245 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFFGAFPN_03283 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
MFFGAFPN_03284 6.57e-178 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
MFFGAFPN_03285 4.22e-144 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MFFGAFPN_03286 1.51e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
MFFGAFPN_03287 1.86e-287 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MFFGAFPN_03288 9.2e-130 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
MFFGAFPN_03289 2.12e-308 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MFFGAFPN_03290 1.49e-233 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFFGAFPN_03291 1.21e-217 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MFFGAFPN_03292 5.21e-182 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MFFGAFPN_03293 3.79e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
MFFGAFPN_03294 0.0 yvrG - - T - - - Histidine kinase
MFFGAFPN_03295 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFFGAFPN_03296 5.07e-32 - - - - - - - -
MFFGAFPN_03297 4.06e-127 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
MFFGAFPN_03298 4.92e-26 - - - S - - - YvrJ protein family
MFFGAFPN_03299 3.22e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
MFFGAFPN_03300 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
MFFGAFPN_03301 3.36e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
MFFGAFPN_03302 4.64e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFGAFPN_03303 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
MFFGAFPN_03304 2.4e-190 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MFFGAFPN_03305 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFFGAFPN_03306 1.21e-236 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFFGAFPN_03307 7.69e-226 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFFGAFPN_03308 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
MFFGAFPN_03309 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
MFFGAFPN_03310 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
MFFGAFPN_03311 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
MFFGAFPN_03312 1.26e-214 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
MFFGAFPN_03313 6.57e-179 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
MFFGAFPN_03314 1.23e-153 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
MFFGAFPN_03315 6.19e-201 yvgN - - S - - - reductase
MFFGAFPN_03316 9.32e-112 yvgO - - - - - - -
MFFGAFPN_03317 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
MFFGAFPN_03318 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MFFGAFPN_03319 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MFFGAFPN_03320 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MFFGAFPN_03321 3.88e-140 yvgT - - S - - - membrane
MFFGAFPN_03322 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
MFFGAFPN_03323 3.45e-137 bdbD - - O - - - Thioredoxin
MFFGAFPN_03324 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
MFFGAFPN_03325 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MFFGAFPN_03326 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
MFFGAFPN_03327 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
MFFGAFPN_03328 2.42e-248 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
MFFGAFPN_03329 5.09e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MFFGAFPN_03330 0.0 - - - S - - - Fusaric acid resistance protein-like
MFFGAFPN_03331 8.22e-97 yvaD - - S - - - Family of unknown function (DUF5360)
MFFGAFPN_03332 2.04e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
MFFGAFPN_03333 8.55e-129 - - - K - - - Bacterial regulatory proteins, tetR family
MFFGAFPN_03334 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MFFGAFPN_03336 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MFFGAFPN_03337 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MFFGAFPN_03338 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
MFFGAFPN_03339 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
MFFGAFPN_03340 4.04e-194 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
MFFGAFPN_03341 3.44e-48 yvzC - - K - - - transcriptional
MFFGAFPN_03342 2.36e-91 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
MFFGAFPN_03343 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
MFFGAFPN_03344 3.85e-72 yvaP - - K - - - transcriptional
MFFGAFPN_03345 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MFFGAFPN_03346 2.26e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MFFGAFPN_03347 3.93e-219 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MFFGAFPN_03348 6.3e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MFFGAFPN_03349 1.04e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MFFGAFPN_03350 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
MFFGAFPN_03351 9.67e-137 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MFFGAFPN_03352 1.49e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MFFGAFPN_03353 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MFFGAFPN_03354 1.13e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MFFGAFPN_03355 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
MFFGAFPN_03356 7.95e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
MFFGAFPN_03357 4.91e-144 yvbH - - S - - - YvbH-like oligomerisation region
MFFGAFPN_03358 7.97e-157 yvbI - - M - - - Membrane
MFFGAFPN_03359 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MFFGAFPN_03360 6.87e-106 yvbK - - K - - - acetyltransferase
MFFGAFPN_03361 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MFFGAFPN_03362 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
MFFGAFPN_03363 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MFFGAFPN_03364 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MFFGAFPN_03365 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MFFGAFPN_03366 2.42e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MFFGAFPN_03367 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MFFGAFPN_03368 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
MFFGAFPN_03369 2.1e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MFFGAFPN_03370 4.9e-206 yvbU - - K - - - Transcriptional regulator
MFFGAFPN_03371 3.93e-198 yvbV - - EG - - - EamA-like transporter family
MFFGAFPN_03372 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MFFGAFPN_03373 3.35e-246 - - - S - - - Glycosyl hydrolase
MFFGAFPN_03374 2.4e-171 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MFFGAFPN_03375 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MFFGAFPN_03376 3.17e-175 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MFFGAFPN_03377 4.36e-136 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFFGAFPN_03378 6.02e-249 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFFGAFPN_03379 5.01e-171 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
MFFGAFPN_03380 2.13e-202 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
MFFGAFPN_03381 8.47e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
MFFGAFPN_03382 2.93e-263 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
MFFGAFPN_03383 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
MFFGAFPN_03384 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
MFFGAFPN_03385 1.1e-193 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
MFFGAFPN_03386 2.15e-300 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
MFFGAFPN_03387 8.35e-295 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
MFFGAFPN_03388 6.42e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MFFGAFPN_03389 3.96e-145 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
MFFGAFPN_03390 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MFFGAFPN_03391 9.59e-304 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MFFGAFPN_03392 5.69e-44 yvfG - - S - - - YvfG protein
MFFGAFPN_03393 6.2e-240 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
MFFGAFPN_03394 2.14e-278 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
MFFGAFPN_03395 4.44e-74 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
MFFGAFPN_03396 3.19e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MFFGAFPN_03397 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MFFGAFPN_03398 3.08e-242 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MFFGAFPN_03399 9.86e-262 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
MFFGAFPN_03400 4.97e-248 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
MFFGAFPN_03401 3.59e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
MFFGAFPN_03402 2.4e-276 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MFFGAFPN_03403 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
MFFGAFPN_03404 1.4e-284 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
MFFGAFPN_03405 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
MFFGAFPN_03406 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
MFFGAFPN_03407 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
MFFGAFPN_03408 1.45e-97 - - - K ko:K19417 - ko00000,ko03000 transcriptional
MFFGAFPN_03409 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
MFFGAFPN_03411 8.97e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
MFFGAFPN_03412 4.48e-96 - - - S - - - Protein of unknown function (DUF3237)
MFFGAFPN_03413 1.69e-160 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MFFGAFPN_03414 0.0 pbpE - - V - - - Beta-lactamase
MFFGAFPN_03415 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
MFFGAFPN_03416 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
MFFGAFPN_03417 0.0 ybeC - - E - - - amino acid
MFFGAFPN_03418 1.17e-137 yvdT_1 - - K - - - Transcriptional regulator
MFFGAFPN_03419 6.31e-68 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MFFGAFPN_03420 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
MFFGAFPN_03421 5.53e-122 yvdQ - - S - - - Protein of unknown function (DUF3231)
MFFGAFPN_03422 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
MFFGAFPN_03423 2.71e-233 - - - S - - - Patatin-like phospholipase
MFFGAFPN_03425 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MFFGAFPN_03426 1.01e-156 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MFFGAFPN_03427 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MFFGAFPN_03428 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
MFFGAFPN_03429 8e-197 malA - - S - - - Protein of unknown function (DUF1189)
MFFGAFPN_03430 6.84e-190 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
MFFGAFPN_03431 8.65e-311 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
MFFGAFPN_03432 5.95e-302 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
MFFGAFPN_03433 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
MFFGAFPN_03434 1.54e-221 yvdE - - K - - - Transcriptional regulator
MFFGAFPN_03435 5.37e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
MFFGAFPN_03436 4.54e-70 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
MFFGAFPN_03437 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
MFFGAFPN_03438 3.73e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
MFFGAFPN_03439 1.15e-234 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFFGAFPN_03440 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
MFFGAFPN_03441 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFGAFPN_03442 2.78e-251 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
MFFGAFPN_03443 3.16e-170 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFFGAFPN_03444 1.13e-44 - - - - - - - -
MFFGAFPN_03445 5.64e-183 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
MFFGAFPN_03446 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
MFFGAFPN_03447 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MFFGAFPN_03448 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MFFGAFPN_03449 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MFFGAFPN_03450 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MFFGAFPN_03451 1.18e-225 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MFFGAFPN_03452 1.89e-185 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
MFFGAFPN_03453 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
MFFGAFPN_03454 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MFFGAFPN_03456 0.0 - - - - - - - -
MFFGAFPN_03457 3.26e-95 - - - - - - - -
MFFGAFPN_03458 1.45e-143 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
MFFGAFPN_03459 2.29e-175 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MFFGAFPN_03460 6.55e-167 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MFFGAFPN_03461 6.92e-148 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MFFGAFPN_03462 4.96e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
MFFGAFPN_03463 4.66e-295 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MFFGAFPN_03464 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MFFGAFPN_03465 4e-280 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MFFGAFPN_03466 6.12e-179 yvpB - - NU - - - protein conserved in bacteria
MFFGAFPN_03467 1.1e-153 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
MFFGAFPN_03468 1.52e-120 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
MFFGAFPN_03469 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MFFGAFPN_03470 1.24e-209 yvoD - - P - - - COG0370 Fe2 transport system protein B
MFFGAFPN_03471 3.18e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MFFGAFPN_03472 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MFFGAFPN_03473 2.93e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MFFGAFPN_03474 3.66e-167 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MFFGAFPN_03475 3.02e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
MFFGAFPN_03476 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
MFFGAFPN_03477 9.4e-110 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
MFFGAFPN_03478 9.32e-293 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MFFGAFPN_03479 2.49e-177 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
MFFGAFPN_03480 1.03e-112 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
MFFGAFPN_03481 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
MFFGAFPN_03482 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
MFFGAFPN_03483 6.11e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MFFGAFPN_03484 2.36e-220 yvlB - - S - - - Putative adhesin
MFFGAFPN_03485 3.3e-64 yvlA - - - - - - -
MFFGAFPN_03486 2.25e-45 yvkN - - - - - - -
MFFGAFPN_03487 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MFFGAFPN_03488 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MFFGAFPN_03489 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MFFGAFPN_03490 2.54e-42 csbA - - S - - - protein conserved in bacteria
MFFGAFPN_03491 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
MFFGAFPN_03492 9.63e-130 yvkB - - K - - - Transcriptional regulator
MFFGAFPN_03493 8.67e-295 yvkA - - P - - - -transporter
MFFGAFPN_03494 6.4e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFFGAFPN_03495 1.38e-73 swrA - - S - - - Swarming motility protein
MFFGAFPN_03496 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MFFGAFPN_03497 1.1e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MFFGAFPN_03498 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
MFFGAFPN_03499 3.78e-74 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
MFFGAFPN_03500 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MFFGAFPN_03501 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MFFGAFPN_03502 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MFFGAFPN_03503 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MFFGAFPN_03504 9.14e-88 - - - - - - - -
MFFGAFPN_03505 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
MFFGAFPN_03506 5.15e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
MFFGAFPN_03507 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MFFGAFPN_03508 1.1e-76 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
MFFGAFPN_03509 1.01e-106 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MFFGAFPN_03510 2.58e-41 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MFFGAFPN_03511 3.38e-94 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MFFGAFPN_03512 6.92e-92 yviE - - - - - - -
MFFGAFPN_03513 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
MFFGAFPN_03514 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
MFFGAFPN_03515 7.06e-102 yvyG - - NOU - - - FlgN protein
MFFGAFPN_03516 4.32e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
MFFGAFPN_03517 1.06e-95 yvyF - - S - - - flagellar protein
MFFGAFPN_03518 1.78e-159 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
MFFGAFPN_03519 1.04e-60 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
MFFGAFPN_03520 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MFFGAFPN_03521 2.15e-199 degV - - S - - - protein conserved in bacteria
MFFGAFPN_03522 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFFGAFPN_03523 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MFFGAFPN_03524 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
MFFGAFPN_03525 5.04e-225 yvhJ - - K - - - Transcriptional regulator
MFFGAFPN_03526 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MFFGAFPN_03527 5.87e-297 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
MFFGAFPN_03528 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
MFFGAFPN_03529 5.79e-147 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
MFFGAFPN_03530 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
MFFGAFPN_03531 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MFFGAFPN_03532 1.39e-279 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
MFFGAFPN_03533 2.58e-316 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MFFGAFPN_03534 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MFFGAFPN_03535 1.78e-108 - - - M - - - Glycosyltransferase like family 2
MFFGAFPN_03536 2.14e-263 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MFFGAFPN_03537 0.0 lytB - - D - - - Stage II sporulation protein
MFFGAFPN_03538 9.07e-16 - - - - - - - -
MFFGAFPN_03539 1.16e-211 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MFFGAFPN_03540 9e-276 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MFFGAFPN_03541 1.48e-103 - - - M - - - Glycosyltransferase like family 2
MFFGAFPN_03542 1.37e-117 - - - M - - - Glycosyl transferases group 1
MFFGAFPN_03544 3.9e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MFFGAFPN_03545 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MFFGAFPN_03546 1.67e-168 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
MFFGAFPN_03547 1.09e-101 - - - - - - - -
MFFGAFPN_03548 3.8e-68 - - - - - - - -
MFFGAFPN_03549 5.36e-249 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MFFGAFPN_03550 4.14e-106 - - - M - - - Glycosyltransferase like family 2
MFFGAFPN_03551 6.53e-180 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MFFGAFPN_03552 1.32e-73 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
MFFGAFPN_03553 6.82e-111 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MFFGAFPN_03554 1.09e-116 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MFFGAFPN_03555 2.07e-134 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
MFFGAFPN_03556 5.68e-186 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
MFFGAFPN_03557 6.69e-110 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - M ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MFFGAFPN_03558 1.42e-235 tarL 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MFFGAFPN_03559 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MFFGAFPN_03560 4.72e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MFFGAFPN_03561 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
MFFGAFPN_03562 1.38e-253 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
MFFGAFPN_03563 1.04e-271 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
MFFGAFPN_03564 9.1e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MFFGAFPN_03565 1.48e-222 ywtF_2 - - K - - - Transcriptional regulator
MFFGAFPN_03566 7.24e-205 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MFFGAFPN_03567 1.86e-302 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MFFGAFPN_03568 4.62e-29 ywtC - - - - - - -
MFFGAFPN_03569 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MFFGAFPN_03570 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
MFFGAFPN_03571 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
MFFGAFPN_03572 1.09e-226 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
MFFGAFPN_03573 1.85e-206 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MFFGAFPN_03574 3.79e-83 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MFFGAFPN_03575 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MFFGAFPN_03576 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MFFGAFPN_03577 9.04e-204 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
MFFGAFPN_03578 1.14e-118 batE - - T - - - Sh3 type 3 domain protein
MFFGAFPN_03579 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
MFFGAFPN_03580 8.76e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
MFFGAFPN_03581 1.06e-186 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
MFFGAFPN_03582 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MFFGAFPN_03583 3.36e-218 alsR - - K - - - LysR substrate binding domain
MFFGAFPN_03584 1.13e-279 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MFFGAFPN_03585 5.05e-161 ywrJ - - - - - - -
MFFGAFPN_03586 1.95e-175 cotB - - - ko:K06325 - ko00000 -
MFFGAFPN_03587 2.64e-268 cotH - - M ko:K06330 - ko00000 Spore Coat
MFFGAFPN_03588 2.17e-16 - - - - - - - -
MFFGAFPN_03589 1.77e-142 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MFFGAFPN_03590 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
MFFGAFPN_03591 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
MFFGAFPN_03592 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
MFFGAFPN_03593 4.53e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
MFFGAFPN_03594 2.89e-112 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
MFFGAFPN_03596 6.11e-129 ywqN - - S - - - NAD(P)H-dependent
MFFGAFPN_03597 3.33e-209 - - - K - - - Transcriptional regulator
MFFGAFPN_03598 8.38e-148 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MFFGAFPN_03600 4.15e-100 ywqJ - - S - - - Pre-toxin TG
MFFGAFPN_03601 1.3e-23 - - - - - - - -
MFFGAFPN_03602 1.77e-26 - - - - - - - -
MFFGAFPN_03603 1.41e-262 ywqJ - - S - - - Pre-toxin TG
MFFGAFPN_03604 2.47e-50 ywqI - - S - - - Family of unknown function (DUF5344)
MFFGAFPN_03606 9.88e-195 ywqG - - S - - - Domain of unknown function (DUF1963)
MFFGAFPN_03607 6.62e-313 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MFFGAFPN_03608 1.75e-180 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
MFFGAFPN_03609 7.15e-151 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
MFFGAFPN_03610 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
MFFGAFPN_03611 3.6e-25 - - - - - - - -
MFFGAFPN_03612 0.0 ywqB - - S - - - SWIM zinc finger
MFFGAFPN_03613 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
MFFGAFPN_03614 2.06e-199 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MFFGAFPN_03615 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MFFGAFPN_03616 8.53e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
MFFGAFPN_03617 3.04e-87 ywpG - - - - - - -
MFFGAFPN_03618 2.53e-88 ywpF - - S - - - YwpF-like protein
MFFGAFPN_03619 2.21e-66 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
MFFGAFPN_03620 1.16e-195 ywpD - - T - - - Histidine kinase
MFFGAFPN_03621 1.61e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MFFGAFPN_03622 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MFFGAFPN_03623 4.47e-256 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
MFFGAFPN_03624 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
MFFGAFPN_03625 1.02e-171 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
MFFGAFPN_03626 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
MFFGAFPN_03627 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
MFFGAFPN_03628 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
MFFGAFPN_03629 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MFFGAFPN_03630 1.02e-312 ywoF - - P - - - Right handed beta helix region
MFFGAFPN_03631 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
MFFGAFPN_03632 1.27e-305 ywoD - - EGP - - - Major facilitator superfamily
MFFGAFPN_03633 3.5e-132 yjgF - - Q - - - Isochorismatase family
MFFGAFPN_03634 5.89e-100 - - - - - - - -
MFFGAFPN_03635 6.5e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
MFFGAFPN_03636 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
MFFGAFPN_03637 1.21e-134 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
MFFGAFPN_03638 8.15e-92 ywnJ - - S - - - VanZ like family
MFFGAFPN_03639 1.07e-160 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
MFFGAFPN_03640 5.19e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
MFFGAFPN_03641 1.01e-17 ywnC - - S - - - Family of unknown function (DUF5362)
MFFGAFPN_03642 1.43e-91 ywnF - - S - - - Family of unknown function (DUF5392)
MFFGAFPN_03643 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MFFGAFPN_03644 1.97e-183 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
MFFGAFPN_03645 1.24e-77 ywnC - - S - - - Family of unknown function (DUF5362)
MFFGAFPN_03646 6.88e-144 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
MFFGAFPN_03647 4.58e-85 ywnA - - K - - - Transcriptional regulator
MFFGAFPN_03648 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MFFGAFPN_03649 1.85e-82 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
MFFGAFPN_03650 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
MFFGAFPN_03652 1.11e-21 csbD - - K - - - CsbD-like
MFFGAFPN_03653 7.7e-110 ywmF - - S - - - Peptidase M50
MFFGAFPN_03655 6.22e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MFFGAFPN_03656 1.08e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MFFGAFPN_03657 1.5e-185 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MFFGAFPN_03659 1.19e-154 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MFFGAFPN_03660 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MFFGAFPN_03661 5.9e-235 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
MFFGAFPN_03662 1e-305 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MFFGAFPN_03663 1.97e-173 ywmB - - S - - - TATA-box binding
MFFGAFPN_03664 4.54e-45 ywzB - - S - - - membrane
MFFGAFPN_03665 6.12e-115 ywmA - - - - - - -
MFFGAFPN_03666 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MFFGAFPN_03667 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MFFGAFPN_03668 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MFFGAFPN_03669 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MFFGAFPN_03670 7.94e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MFFGAFPN_03671 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MFFGAFPN_03672 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MFFGAFPN_03673 3.51e-166 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MFFGAFPN_03674 6.39e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
MFFGAFPN_03675 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MFFGAFPN_03676 2.52e-302 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MFFGAFPN_03677 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
MFFGAFPN_03678 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
MFFGAFPN_03679 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MFFGAFPN_03680 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
MFFGAFPN_03681 1.22e-249 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MFFGAFPN_03682 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
MFFGAFPN_03683 1.14e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
MFFGAFPN_03684 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
MFFGAFPN_03686 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MFFGAFPN_03687 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MFFGAFPN_03688 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFFGAFPN_03689 6.01e-117 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MFFGAFPN_03690 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
MFFGAFPN_03691 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
MFFGAFPN_03692 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MFFGAFPN_03693 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
MFFGAFPN_03694 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MFFGAFPN_03695 3.51e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
MFFGAFPN_03696 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MFFGAFPN_03697 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MFFGAFPN_03698 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
MFFGAFPN_03699 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
MFFGAFPN_03700 6.41e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
MFFGAFPN_03701 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MFFGAFPN_03702 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MFFGAFPN_03703 4.06e-267 acdA - - I - - - acyl-CoA dehydrogenase
MFFGAFPN_03704 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
MFFGAFPN_03705 3.34e-287 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MFFGAFPN_03706 2.82e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MFFGAFPN_03707 1.32e-57 ywjC - - - - - - -
MFFGAFPN_03708 4.52e-123 ywjB - - H - - - RibD C-terminal domain
MFFGAFPN_03709 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
MFFGAFPN_03710 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MFFGAFPN_03711 3.42e-158 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
MFFGAFPN_03712 5.59e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
MFFGAFPN_03713 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
MFFGAFPN_03714 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MFFGAFPN_03715 3.53e-110 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
MFFGAFPN_03716 1.06e-178 ywiC - - S - - - YwiC-like protein
MFFGAFPN_03717 5.65e-169 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
MFFGAFPN_03718 1.2e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
MFFGAFPN_03719 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MFFGAFPN_03720 4.64e-96 ywiB - - S - - - protein conserved in bacteria
MFFGAFPN_03721 3.71e-12 - - - S - - - Bacteriocin subtilosin A
MFFGAFPN_03722 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
MFFGAFPN_03724 1.75e-168 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MFFGAFPN_03725 3.66e-292 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
MFFGAFPN_03726 2.42e-276 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
MFFGAFPN_03727 3.14e-313 - - - L - - - Peptidase, M16
MFFGAFPN_03729 0.0 ywhL - - CO - - - amine dehydrogenase activity
MFFGAFPN_03730 6.28e-280 ywhK - - CO - - - amine dehydrogenase activity
MFFGAFPN_03731 5.77e-100 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MFFGAFPN_03735 1.3e-10 - - - - - - - -
MFFGAFPN_03738 1.4e-74 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MFFGAFPN_03740 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
MFFGAFPN_03741 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MFFGAFPN_03742 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MFFGAFPN_03743 7.83e-123 ywhD - - S - - - YwhD family
MFFGAFPN_03744 3.29e-154 ywhC - - S - - - Peptidase family M50
MFFGAFPN_03745 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
MFFGAFPN_03746 1.45e-93 ywhA - - K - - - Transcriptional regulator
MFFGAFPN_03747 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MFFGAFPN_03749 2.62e-301 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
MFFGAFPN_03750 3.15e-103 yffB - - K - - - Transcriptional regulator
MFFGAFPN_03751 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
MFFGAFPN_03752 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
MFFGAFPN_03753 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
MFFGAFPN_03754 4.63e-146 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
MFFGAFPN_03755 6.4e-204 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
MFFGAFPN_03756 6.16e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MFFGAFPN_03757 5.53e-211 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
MFFGAFPN_03758 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
MFFGAFPN_03759 1.4e-186 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
MFFGAFPN_03760 2.77e-175 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
MFFGAFPN_03761 1.05e-295 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
MFFGAFPN_03762 3.91e-268 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
MFFGAFPN_03763 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MFFGAFPN_03764 3.14e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFFGAFPN_03765 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MFFGAFPN_03766 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MFFGAFPN_03767 5.41e-275 ywfA - - EGP - - - -transporter
MFFGAFPN_03768 8.84e-317 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MFFGAFPN_03769 0.0 rocB - - E - - - arginine degradation protein
MFFGAFPN_03770 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
MFFGAFPN_03771 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MFFGAFPN_03772 3.7e-101 - - - - - - - -
MFFGAFPN_03773 3.73e-113 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
MFFGAFPN_03774 1.41e-205 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MFFGAFPN_03775 3.7e-233 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MFFGAFPN_03776 7.45e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MFFGAFPN_03777 1.35e-238 spsG - - M - - - Spore Coat
MFFGAFPN_03778 1.55e-167 spsF - - M ko:K07257 - ko00000 Spore Coat
MFFGAFPN_03779 1.95e-271 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
MFFGAFPN_03780 1.41e-208 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
MFFGAFPN_03781 3.73e-284 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
MFFGAFPN_03782 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
MFFGAFPN_03783 6.64e-186 spsA - - M - - - Spore Coat
MFFGAFPN_03784 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MFFGAFPN_03785 1.59e-78 ywdK - - S - - - small membrane protein
MFFGAFPN_03786 1.78e-301 ywdJ - - F - - - Xanthine uracil
MFFGAFPN_03787 9.23e-65 ywdI - - S - - - Family of unknown function (DUF5327)
MFFGAFPN_03788 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MFFGAFPN_03789 2.32e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MFFGAFPN_03790 6.65e-192 ywdF - - S - - - Glycosyltransferase like family 2
MFFGAFPN_03792 3.56e-145 ywdD - - - - - - -
MFFGAFPN_03793 1.6e-75 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
MFFGAFPN_03794 2.21e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MFFGAFPN_03795 6.19e-39 ywdA - - - - - - -
MFFGAFPN_03796 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MFFGAFPN_03797 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MFFGAFPN_03798 4.82e-179 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
MFFGAFPN_03799 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
MFFGAFPN_03801 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MFFGAFPN_03802 3.44e-238 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MFFGAFPN_03803 2.69e-177 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
MFFGAFPN_03804 1.26e-268 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MFFGAFPN_03805 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
MFFGAFPN_03806 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
MFFGAFPN_03807 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
MFFGAFPN_03808 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MFFGAFPN_03809 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MFFGAFPN_03810 5.11e-49 ydaS - - S - - - membrane
MFFGAFPN_03811 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MFFGAFPN_03812 1.12e-290 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MFFGAFPN_03813 2.25e-75 gtcA - - S - - - GtrA-like protein
MFFGAFPN_03814 3.42e-158 ywcC - - K - - - transcriptional regulator
MFFGAFPN_03816 2.49e-63 ywcB - - S - - - Protein of unknown function, DUF485
MFFGAFPN_03817 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MFFGAFPN_03818 1.88e-143 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
MFFGAFPN_03819 4.4e-308 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
MFFGAFPN_03820 2.42e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
MFFGAFPN_03821 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
MFFGAFPN_03822 1.49e-147 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MFFGAFPN_03823 1.32e-184 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MFFGAFPN_03824 2.7e-203 ywbI - - K - - - Transcriptional regulator
MFFGAFPN_03825 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MFFGAFPN_03826 2.44e-143 ywbG - - M - - - effector of murein hydrolase
MFFGAFPN_03827 7.46e-278 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
MFFGAFPN_03828 6.33e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
MFFGAFPN_03829 5.68e-280 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
MFFGAFPN_03830 4.01e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
MFFGAFPN_03831 1.75e-312 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFFGAFPN_03832 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MFFGAFPN_03833 9.33e-309 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MFFGAFPN_03834 2.91e-192 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
MFFGAFPN_03835 3.11e-215 gspA - - M - - - General stress
MFFGAFPN_03836 1.81e-160 ywaF - - S - - - Integral membrane protein
MFFGAFPN_03837 7.22e-114 ywaE - - K - - - Transcriptional regulator
MFFGAFPN_03838 1.23e-294 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MFFGAFPN_03839 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
MFFGAFPN_03840 1.6e-54 - - - K - - - Helix-turn-helix XRE-family like proteins
MFFGAFPN_03841 1.45e-45 - - - K - - - Helix-turn-helix domain
MFFGAFPN_03842 5.58e-64 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MFFGAFPN_03843 1.3e-163 - - - EGP - - - Permeases of the major facilitator superfamily
MFFGAFPN_03844 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
MFFGAFPN_03845 5.7e-210 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
MFFGAFPN_03846 1.27e-20 - - - S - - - D-Ala-teichoic acid biosynthesis protein
MFFGAFPN_03847 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFFGAFPN_03848 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
MFFGAFPN_03849 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFFGAFPN_03850 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MFFGAFPN_03851 4.83e-177 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MFFGAFPN_03852 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MFFGAFPN_03853 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MFFGAFPN_03854 8.33e-68 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MFFGAFPN_03855 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFFGAFPN_03856 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
MFFGAFPN_03857 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
MFFGAFPN_03858 8.94e-28 yxzF - - - - - - -
MFFGAFPN_03859 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MFFGAFPN_03860 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MFFGAFPN_03861 1.95e-271 yxlH - - EGP - - - Major Facilitator Superfamily
MFFGAFPN_03862 3.96e-179 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MFFGAFPN_03863 2.35e-210 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFGAFPN_03864 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
MFFGAFPN_03865 2.92e-42 - - - - - - - -
MFFGAFPN_03866 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
MFFGAFPN_03867 9.06e-125 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MFFGAFPN_03868 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
MFFGAFPN_03869 3.73e-202 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MFFGAFPN_03870 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
MFFGAFPN_03871 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
MFFGAFPN_03872 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
MFFGAFPN_03873 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
MFFGAFPN_03874 2.67e-308 cimH - - C - - - COG3493 Na citrate symporter
MFFGAFPN_03875 0.0 - - - O - - - Peptidase family M48
MFFGAFPN_03877 1.58e-200 yxkH - - G - - - Polysaccharide deacetylase
MFFGAFPN_03878 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MFFGAFPN_03879 1.36e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
MFFGAFPN_03880 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MFFGAFPN_03881 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MFFGAFPN_03882 1.58e-181 - - - - - - - -
MFFGAFPN_03883 4.26e-249 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MFFGAFPN_03884 3.81e-100 - - - S - - - Protein of unknown function (DUF1453)
MFFGAFPN_03885 8.12e-253 - - - T - - - Signal transduction histidine kinase
MFFGAFPN_03886 4.65e-149 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
MFFGAFPN_03887 3.16e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MFFGAFPN_03890 1.43e-111 yxjI - - S - - - LURP-one-related
MFFGAFPN_03891 7.42e-278 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
MFFGAFPN_03892 4.45e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
MFFGAFPN_03893 1.37e-174 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MFFGAFPN_03894 4.86e-150 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MFFGAFPN_03895 6.6e-168 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MFFGAFPN_03896 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
MFFGAFPN_03897 3.2e-181 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
MFFGAFPN_03898 2.98e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MFFGAFPN_03899 2.43e-132 - - - T - - - Domain of unknown function (DUF4163)
MFFGAFPN_03900 1.88e-62 yxiS - - - - - - -
MFFGAFPN_03901 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MFFGAFPN_03902 2.33e-283 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
MFFGAFPN_03903 5.08e-183 bglS - - M - - - licheninase activity
MFFGAFPN_03904 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
MFFGAFPN_03905 7.23e-141 - - - - - - - -
MFFGAFPN_03906 7.67e-292 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
MFFGAFPN_03907 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MFFGAFPN_03908 1.13e-270 - - - E - - - GDSL-like Lipase/Acylhydrolase
MFFGAFPN_03909 4.92e-70 - - - K - - - Transcriptional regulator PadR-like family
MFFGAFPN_03910 8.02e-80 - - - S - - - Protein of unknown function (DUF2812)
MFFGAFPN_03913 5.77e-58 yxiJ - - S - - - YxiJ-like protein
MFFGAFPN_03914 4.36e-46 yxiI - - S - - - Protein of unknown function (DUF2716)
MFFGAFPN_03915 4.83e-26 - - - - - - - -
MFFGAFPN_03919 0.0 wapA - - M - - - COG3209 Rhs family protein
MFFGAFPN_03920 4.18e-210 yxxF - - EG - - - EamA-like transporter family
MFFGAFPN_03921 5.52e-160 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFFGAFPN_03922 9.17e-157 - 1.14.11.45 - E ko:K20418 - ko00000,ko01000 2OG-Fe dioxygenase
MFFGAFPN_03923 2e-93 yxiE - - T - - - Belongs to the universal stress protein A family
MFFGAFPN_03924 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MFFGAFPN_03925 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MFFGAFPN_03926 1.11e-63 - - - - - - - -
MFFGAFPN_03927 9.25e-103 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
MFFGAFPN_03928 0.0 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
MFFGAFPN_03929 1.33e-52 yxiC - - S - - - Family of unknown function (DUF5344)
MFFGAFPN_03930 1.26e-35 - - - S - - - Domain of unknown function (DUF5082)
MFFGAFPN_03931 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
MFFGAFPN_03932 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MFFGAFPN_03933 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
MFFGAFPN_03934 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MFFGAFPN_03935 3.18e-299 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
MFFGAFPN_03936 4.85e-231 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MFFGAFPN_03937 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MFFGAFPN_03938 3.3e-298 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
MFFGAFPN_03939 1.57e-262 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MFFGAFPN_03940 4.8e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MFFGAFPN_03941 2.02e-220 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MFFGAFPN_03942 2.51e-195 - - - S - - - Domain of Unknown Function (DUF1206)
MFFGAFPN_03943 7.08e-252 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
MFFGAFPN_03944 0.0 yxeQ - - S - - - MmgE/PrpD family
MFFGAFPN_03945 2.37e-271 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
MFFGAFPN_03946 3.94e-170 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MFFGAFPN_03947 1.81e-149 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MFFGAFPN_03948 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MFFGAFPN_03949 2.99e-119 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFFGAFPN_03950 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MFFGAFPN_03951 6.41e-236 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
MFFGAFPN_03952 3.29e-193 yxeH - - S - - - hydrolases of the HAD superfamily
MFFGAFPN_03955 7.32e-42 yxeE - - - - - - -
MFFGAFPN_03956 7.57e-28 yxeD - - - - - - -
MFFGAFPN_03957 9.65e-91 - - - - - - - -
MFFGAFPN_03958 2.03e-224 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFFGAFPN_03959 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
MFFGAFPN_03960 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MFFGAFPN_03961 9.39e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MFFGAFPN_03962 9.03e-230 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFFGAFPN_03963 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFFGAFPN_03964 5.71e-204 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MFFGAFPN_03965 5.63e-194 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MFFGAFPN_03966 1.87e-213 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
MFFGAFPN_03967 4.44e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MFFGAFPN_03968 6.64e-295 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
MFFGAFPN_03969 7.09e-222 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MFFGAFPN_03970 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MFFGAFPN_03971 1.23e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MFFGAFPN_03972 1.64e-198 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MFFGAFPN_03973 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MFFGAFPN_03974 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MFFGAFPN_03975 2.04e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
MFFGAFPN_03977 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
MFFGAFPN_03978 5.91e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MFFGAFPN_03979 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
MFFGAFPN_03981 4.15e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MFFGAFPN_03982 2.96e-265 yxbF - - K - - - Bacterial regulatory proteins, tetR family
MFFGAFPN_03983 3.42e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MFFGAFPN_03984 3.14e-109 yxbD 3.2.2.20 - K ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Acetyltransferase (GNAT) domain
MFFGAFPN_03985 1.16e-239 - - - S - - - A domain family that is part of the cupin metalloenzyme superfamily.
MFFGAFPN_03986 1.83e-175 yxbB - - Q - - - Met-10+ like-protein
MFFGAFPN_03987 1.49e-58 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
MFFGAFPN_03988 8.99e-114 yxnB - - - - - - -
MFFGAFPN_03989 0.0 - 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MFFGAFPN_03990 1.8e-271 yxaM - - U - - - MFS_1 like family
MFFGAFPN_03991 2.63e-137 yxaL - - S - - - PQQ-like domain
MFFGAFPN_03992 2.38e-84 - - - S - - - Family of unknown function (DUF5391)
MFFGAFPN_03993 4.03e-99 yxaI - - S - - - membrane protein domain
MFFGAFPN_03994 8.83e-285 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
MFFGAFPN_03995 3.65e-251 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
MFFGAFPN_03996 3.91e-130 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
MFFGAFPN_03997 1.23e-254 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MFFGAFPN_03998 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MFFGAFPN_03999 3.23e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
MFFGAFPN_04000 1.27e-152 yxaC - - M - - - effector of murein hydrolase
MFFGAFPN_04001 7.3e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
MFFGAFPN_04002 4.71e-263 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MFFGAFPN_04003 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
MFFGAFPN_04004 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MFFGAFPN_04005 2.05e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
MFFGAFPN_04006 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MFFGAFPN_04007 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
MFFGAFPN_04008 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
MFFGAFPN_04009 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MFFGAFPN_04010 6.03e-21 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MFFGAFPN_04011 1.13e-158 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
MFFGAFPN_04012 4.13e-24 - - - - - - - -
MFFGAFPN_04013 2.72e-152 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MFFGAFPN_04014 8.4e-143 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFFGAFPN_04015 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
MFFGAFPN_04016 2.37e-94 - - - J - - - COG0617 tRNA nucleotidyltransferase poly(A) polymerase
MFFGAFPN_04017 2.66e-262 - - - S - - - Protein of unknown function DUF262
MFFGAFPN_04018 0.0 - - - L - - - DEAD-like helicases superfamily
MFFGAFPN_04019 2.99e-127 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
MFFGAFPN_04020 6.08e-147 - - - L - - - Recombinase
MFFGAFPN_04021 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MFFGAFPN_04023 2.24e-87 - - - - - - - -
MFFGAFPN_04024 2.12e-296 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MFFGAFPN_04026 5.5e-42 yycQ - - S - - - Protein of unknown function (DUF2651)
MFFGAFPN_04027 2.53e-265 yycP - - - - - - -
MFFGAFPN_04028 5.61e-168 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MFFGAFPN_04029 5.04e-109 yycN - - K - - - Acetyltransferase
MFFGAFPN_04030 1.75e-238 - - - S - - - aspartate phosphatase
MFFGAFPN_04032 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
MFFGAFPN_04033 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MFFGAFPN_04034 6.41e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
MFFGAFPN_04035 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MFFGAFPN_04036 1.5e-213 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MFFGAFPN_04037 6.75e-122 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
MFFGAFPN_04038 1.15e-98 - - - S - - - Peptidase propeptide and YPEB domain
MFFGAFPN_04039 2.2e-42 - - - S - - - Peptidase propeptide and YPEB domain
MFFGAFPN_04040 1.56e-277 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFFGAFPN_04041 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MFFGAFPN_04042 2.83e-199 yycI - - S - - - protein conserved in bacteria
MFFGAFPN_04043 0.0 yycH - - S - - - protein conserved in bacteria
MFFGAFPN_04044 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFFGAFPN_04045 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFFGAFPN_04050 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MFFGAFPN_04051 3.29e-99 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFFGAFPN_04052 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MFFGAFPN_04053 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
MFFGAFPN_04055 1.89e-22 yycC - - K - - - YycC-like protein
MFFGAFPN_04056 1.71e-282 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
MFFGAFPN_04057 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MFFGAFPN_04058 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MFFGAFPN_04059 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MFFGAFPN_04060 1.5e-204 yybS - - S - - - membrane
MFFGAFPN_04062 5.18e-104 cotF - - M ko:K06329 - ko00000 Spore coat protein
MFFGAFPN_04063 3.87e-89 yybR - - K - - - Transcriptional regulator
MFFGAFPN_04064 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
MFFGAFPN_04065 2.73e-91 - - - - - - - -
MFFGAFPN_04067 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MFFGAFPN_04068 2.17e-142 - - - K - - - TipAS antibiotic-recognition domain
MFFGAFPN_04069 6.85e-182 - - - - - - - -
MFFGAFPN_04070 1.23e-87 - - - S - - - SnoaL-like domain
MFFGAFPN_04071 3.28e-161 yybG - - S - - - Pentapeptide repeat-containing protein
MFFGAFPN_04072 2.9e-275 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MFFGAFPN_04073 1.07e-209 yybE - - K - - - Transcriptional regulator
MFFGAFPN_04074 5.1e-102 yjcF - - S - - - Acetyltransferase (GNAT) domain
MFFGAFPN_04075 3.49e-97 yybC - - - - - - -
MFFGAFPN_04076 3.44e-161 - - - S - - - Metallo-beta-lactamase superfamily
MFFGAFPN_04077 4.54e-100 yybA - - K - - - transcriptional
MFFGAFPN_04078 2.94e-90 yjcF - - S - - - Acetyltransferase (GNAT) domain
MFFGAFPN_04079 8.63e-125 yyaS - - S ko:K07149 - ko00000 Membrane
MFFGAFPN_04080 4.7e-120 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
MFFGAFPN_04081 2.13e-85 - - - S - - - YjbR
MFFGAFPN_04082 7.09e-136 yyaP - - H - - - RibD C-terminal domain
MFFGAFPN_04083 5.69e-314 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
MFFGAFPN_04084 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
MFFGAFPN_04085 3.89e-211 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
MFFGAFPN_04086 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
MFFGAFPN_04087 1.33e-129 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
MFFGAFPN_04088 7.2e-90 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFFGAFPN_04089 8e-226 ccpB - - K - - - Transcriptional regulator
MFFGAFPN_04090 1.91e-183 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MFFGAFPN_04091 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MFFGAFPN_04092 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MFFGAFPN_04093 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MFFGAFPN_04094 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MFFGAFPN_04095 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MFFGAFPN_04096 7.41e-45 yyzM - - S - - - protein conserved in bacteria
MFFGAFPN_04097 5.34e-227 yyaD - - S - - - Membrane
MFFGAFPN_04098 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
MFFGAFPN_04099 5.62e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MFFGAFPN_04100 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
MFFGAFPN_04101 4.59e-98 - - - S - - - Bacterial PH domain
MFFGAFPN_04102 2.58e-192 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MFFGAFPN_04103 4.13e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MFFGAFPN_04104 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MFFGAFPN_04105 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MFFGAFPN_04106 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
MFFGAFPN_04107 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MFFGAFPN_04108 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)